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Impact Of Structured Internal Medicine Pharmacotherapy Education In Improving Pharmacist Readiness In Transitioning To An Academic Medical Center, Jude Pierre, Erika Dittmar, Heidi Clarke, Radhan B. Gopalani, Stephanie Palma Dec 2025

Impact Of Structured Internal Medicine Pharmacotherapy Education In Improving Pharmacist Readiness In Transitioning To An Academic Medical Center, Jude Pierre, Erika Dittmar, Heidi Clarke, Radhan B. Gopalani, Stephanie Palma

Nursing & Health Sciences Research Journal

Introduction: Baptist Hospital of Miami (BHM) is transitioning to an academic medical center by starting medical residency training in July 2025. As healthcare systems expand, pharmacists must ensure safe medication dispensing and provide real-time clinical decision support. To support this transition, a structured internal medicine pharmacotherapy curriculum was developed to refresh clinical knowledge and enhance confidence among experienced clinical pharmacists.

Methods: A single-site, Institutional Review Board-exempt, quality improvement project was conducted at BHM. Inclusion criteria included Clinical Pharmacists 2s (primarily decentralized pharmacists with ≥ 1 year of pharmacy experience at BHM) who completed a structured pharmacotherapy curriculum from January 2025 …


Mental Health In Adult Oncology Patients, Jenna Pope Dec 2025

Mental Health In Adult Oncology Patients, Jenna Pope

Capstones

Adults with cancer suffer from mental challenges that frequently go under diagnosed and under treated (Fernando et al., 2023). This can lead to lower quality of life, resulting in reduced adherence to treatment, more frequent hospital stays, increased healthcare costs, and increased mortality rates (Matthews et al., 2025). There are currently no policies on mental health screening for adult oncology patients at every outpatient appointment. By consistently utilizing standardized screening tools such as the PHQ-9 and GAD-7 during all oncology appointments, this can close the gap in policy to address mental health needs of these individuals. It is vital to …


Barriers To Mental Health Access Among Immigrant Populations In The U.S., Cecilia Menzinger Dec 2025

Barriers To Mental Health Access Among Immigrant Populations In The U.S., Cecilia Menzinger

Capstones

No abstract provided.


A Retrospective Analysis Of Relapse Rates And Medication Compliance In Bipolar I And Bipolar Ii Disorders: A Comparative Study, Nasir Mehmood, Qudsia Tariq Dec 2025

A Retrospective Analysis Of Relapse Rates And Medication Compliance In Bipolar I And Bipolar Ii Disorders: A Comparative Study, Nasir Mehmood, Qudsia Tariq

Pakistan Journal of Neurological Sciences (PJNS)

Background and objective:

Bipolar disorder is a chronic, serious mental health condition characterized by mood episodes, and medication non-compliance is a significant predictor of relapse. The objective of this study was to investigate the relapse rates and medication compliance in patients with bipolar I and II disorders.

Methods:

This retrospective observational study was conducted at Karwan-e-Hayat Institute for Mental Health Care, Karachi, Pakistan. Medical records of 377 patients diagnosed with bipolar I or bipolar II disorder between July 2019 and June 2022 were retrieved from the Hospital Management System (HMS). Diagnosis was confirmed using DSM-IV criteria. Medication compliance was assessed …


Title Page Only: Nuts, Seeds, And Specific Cardiometabolic Diseases: The Adventist Health Study 2, Montry Se-Lin Suprono Dec 2025

Title Page Only: Nuts, Seeds, And Specific Cardiometabolic Diseases: The Adventist Health Study 2, Montry Se-Lin Suprono

Loma Linda University Electronic Theses, Dissertations & Projects

No abstract provided.


The Effects Of Graded Amounts Of Nicotinic Acid On Cow Health, Colostrum Yield And Quality Of Prepartum Multiparous Jersey Cows And Growth In Their Subsequent Calves, Lydia Joy Valentine Dec 2025

The Effects Of Graded Amounts Of Nicotinic Acid On Cow Health, Colostrum Yield And Quality Of Prepartum Multiparous Jersey Cows And Growth In Their Subsequent Calves, Lydia Joy Valentine

Master's Theses and Capstones

This study evaluated the impact of graded amounts of nicotinic acid (NA) with a negative DCAD diet on cow health, colostrum composition and calf growth performance of Jersey cattle. We hypothesized that NA supplementation would increase IgG concentration of colostrum, increase calf intestinal absorption and growth and improve cow metabolic health. Thirty multiparous Jersey cows were blocked by calving date and assigned to either 0, 8 or 16 g/d of NA supplementation on top of the -40 mEq/kg DCAD dry cow diet. Blood samples were collected weekly for ketone analysis. Urine was collected three times weekly for pH, creatinine and …


Sik2 Inhibitor Grn-300 Enhances Sensitivity To Paclitaxel Treatment In Triple-Negative Breast Cancer, Marc A. Pina Dec 2025

Sik2 Inhibitor Grn-300 Enhances Sensitivity To Paclitaxel Treatment In Triple-Negative Breast Cancer, Marc A. Pina

Dissertations and Theses (Open Access)

Breast cancer is one of the most frequently diagnosed cancers worldwide, with approximately 15% classified as Triple-Negative Breast Cancer (TNBC). TNBC lacks expression of estrogen (ER) and progesterone (PR), and does not overexpress HER-2, leaving patients without effective targeted therapies. As a result, treatment primarily relies on chemotherapy, most commonly paclitaxel, a taxane that stabilize microtubules, disrupts chromosome separation and induces apoptosis. However, TNBCs are an aggressive cancer subtype, and patients often will develop resistance after a few rounds of chemotherapy. This study addresses a critical unmet need for more effective TNBC therapies by targeting Salt-Inducible Kinase 2 (SIK2), which …


Structure And Function Studies On Trna Splicing Endonuclease, Justin G. Underwood Dec 2025

Structure And Function Studies On Trna Splicing Endonuclease, Justin G. Underwood

Dissertations and Theses (Open Access)

A subset of eukaryotic pre-tRNAs have introns that must be spliced out to become mature molecules capable of functioning in translation. This essential processing step is performed by tRNA splicing endonuclease (TSEN), a highly conserved heterotetramer with two catalytic and two structural subunits. In addition to this conserved function, archaeal TSEN also processes pre-rRNA and yeast TSEN cleaves some mRNAs that encode mitochondrial proteins to initiate mRNA degradation. Interestingly, single amino acid mutations in TSEN cause the human Mendelian disease pontocerebellar hypoplasia (PCH) by an unknown mechanism. Recently, several groups have determined the structure of human TSEN, revealing similarities and …


Host-Intrinsic Factors Determine Anti-Tumor Efficacy Of Exercise In Pancreatic Ductal Adenocarcinoma, Sumedha Pareek Dec 2025

Host-Intrinsic Factors Determine Anti-Tumor Efficacy Of Exercise In Pancreatic Ductal Adenocarcinoma, Sumedha Pareek

Dissertations and Theses (Open Access)

Pancreatic Ductal Adenocarcinoma (PDAC) is the third leading cause of cancer-related deaths with a low 5-year relative survival rate of approximately 13.3% for all stages combined. We have previously shown that exercise can improve quality of life and enhance functional capacity among patients with PDAC. Exercise induces a variety of changes in the tumor microenvironment with beneficial effects in several tumor types. However, our understanding of the clinical effects of exercise and the mechanisms that mediate anti-tumor effects are limited in pancreatic cancer.

In this project, using C57BL/6 mice from Taconic Biosciences (Tac) and Jackson Laboratories (Jax), we established a …


A Randomized Controlled Trial Combining House Screening And Insecticide-Treated Nets Reduces Malaria Transmission In Northwestern Ethiopia, Aklilu K. Belay, Abebe Asale, Catherine L. Sole, Abdullahi A. Yusuf, Baldwyn Torto, Zewdu Abro, Menale Kassie, Clifford M. Mutero, David P. Tchouassi Dec 2025

A Randomized Controlled Trial Combining House Screening And Insecticide-Treated Nets Reduces Malaria Transmission In Northwestern Ethiopia, Aklilu K. Belay, Abebe Asale, Catherine L. Sole, Abdullahi A. Yusuf, Baldwyn Torto, Zewdu Abro, Menale Kassie, Clifford M. Mutero, David P. Tchouassi

All Peer-Reviewed Publications

House screening (HS) of doors, eaves, and windows using wire-mesh has demonstrated potential in the integrated vector management of malaria. However, limited epidemiological data are available to guide its implementation across different ecological settings. In a 16-month randomized controlled trial (follow-up period) conducted across three agroecological areas (dry mountain, plateau highland, and semi-arid) in Jabi Tehnan district, northwestern Ethiopia, treatment houses were equipped with HS combined with insecticide-treated nets (ITNs), while control houses received ITNs only. The intervention led to a significant 2.3-fold reduction in indoor malaria vector density, the primary entomologic outcome, largely influenced by An. gambiae s.l. mosquitoes. …


The (Re)New(Ed) Corporation: Foundation For A Stakeholder Regulatory Agenda, Gregory E. Louis Dec 2025

The (Re)New(Ed) Corporation: Foundation For A Stakeholder Regulatory Agenda, Gregory E. Louis

UC Law Business Journal

Amidst an emerging bipartisan consensus on greater corporate social accountability, America First has joined longstanding solicitude about the racial wealth gap. This Article offers yet another take on corporate purpose. As a project of recovering legal memory like Adrian Vermeule’s common good constitutionalism, it examines scholarship on the history of corporate purpose toward answering whether stakeholder capitalism should inform corporate regulation and, if so, how. It concludes from this history that the Anglo-American legal tradition clearly justifies regulators to hold business corporations accountable to the common good. But it also finds in this history a requirement that stakeholder capitalism be …


Cultural Roots Of Eating: A Comparative Analysis Of Organic Discourse And Marketing Practices In China And The United States, Zubing (Jane) Guo Dec 2025

Cultural Roots Of Eating: A Comparative Analysis Of Organic Discourse And Marketing Practices In China And The United States, Zubing (Jane) Guo

Honors Theses

This thesis examines how cultural frameworks influence the development of the organic food market and shape individual attitudes towards the label “organic” in the U.S. and China. While the popularity of organic food has increased in recent years, cognitive and behavioral reactions toward the label “organic” have differed across societies. In the U.S., healthy eating discourse aligns closely with the individualistic culture and atomistic cognitive style, highlighting the importance of salient elements such as specific nutrients or chemical use. In contrast, Chinese healthy eating discourse is based on balance and harmony, which is directly related to traditional Chinese culture of …


A Systems Approach To Shedding Sunlight On A.I. Black Boxes, Ran Xi Dec 2025

A Systems Approach To Shedding Sunlight On A.I. Black Boxes, Ran Xi

Hofstra Law Review

A substantial body of literature has emerged around concerns that machine learning and artificial intelligence systems are opaque, or "black boxes. " The black box nature ofA.I.-powered services and applications has resulted in alarming risks in social life, including insecurity, mistrust, lack of accountability, and exacerbated bias and discrimination. Despite the call to open the black boxes, corresponding legal and regulatory measures tend to run aground due to their infeasibility, inefficacy, and ambiguity. This Article offers a unique perspective on the A.I black box problem. Using systems theory as a heuristic tool, this Article views A.I. as a law-related system …


Nutrient Utilization Efficiency And Antioxidant Profile Of Bc2 Abaca (Musa Textilis Née) Hybrids, Roberto Barba Jr, Antonio Lalusin Dec 2025

Nutrient Utilization Efficiency And Antioxidant Profile Of Bc2 Abaca (Musa Textilis Née) Hybrids, Roberto Barba Jr, Antonio Lalusin

The Philippine Agricultural Scientist

Abaca (Musa textilis Née) is an important fiber crop widely recognized for its superior tensile strength, yet its productivity remains constrained by nutrient inefficiency, poor cropping management, and climatic stresses under manual production systems. Efficient nutrient utilization and an understanding of antioxidant compositions are practically relevant to the productivity of the abaca fiber crop. However, despite the crop’s economic importance, limited studies have examined nutrient uptake dynamics and internal utilization efficiency related to fiber synthesis. This study aimed to demonstrate the nutrient utilization efficiency and antioxidant profiles of BC₂ abaca hybrids in relation to fiber yield and quality. Fiber …


Investigating The Cardiovascular And Autonomic Responses To Energy Drink Consumption: The Role Of Energy And Calorie Content, Sophia Schmidt Dec 2025

Investigating The Cardiovascular And Autonomic Responses To Energy Drink Consumption: The Role Of Energy And Calorie Content, Sophia Schmidt

Honors Theses

Energy drinks (EDs) are among the most consumed functional beverages, often marketed to enhance focus, alertness, and physical performance. Despite their popularity, the combined cardiovascular and autonomic effects of caffeine and sugar during exercise remain poorly understood. The purpose of this study was to examine the acute cardiovascular, metabolic, and autonomic responses to sugar-sweetened (ED-S), non-nutritive sweetened (ED-NNS), and placebo beverages during submaximal cycling in healthy young males.

Nine male participants (age 22.2 ± 2.4 yrs; BMI 26.2 ± 2.9 kg/m²) completed three experimental visits in a randomized, repeated-measures design. Each visit involved ingestion of one drink (ED-S, ED-NNS, or …


A Story Of Life Through Death: An Osteobiography Of Two Individuals From The Late Saxon Period, Isabella Ragazzi Dec 2025

A Story Of Life Through Death: An Osteobiography Of Two Individuals From The Late Saxon Period, Isabella Ragazzi

Honors Theses

The Anglo-Saxons were the most influential inhabitants of the British Isles in the years AD 450-1066, reigning during a time marked by much warfare, pestilence, and famine. Their impact on British history is still seen through archival materials as well as the archeological and bioarchaeological records. A recent development in the field of bioarchaeology is the osteobiography, which places skeletal analysis in context of the overall culture to create the most complete interpretation of the individual and their life history. Involving both traditional bioarchaeological evaluation and isotopic analysis, this method was applied to two Anglo-Saxon skulls donated to the University …


Medicaid Reimbursement For Community Violence Intervention And Prevention (Cvi): A Multi-State Policy Implementation Case Study, Sheetal Ranjan, C. Clare Strange, Katheryne Pugliese Dec 2025

Medicaid Reimbursement For Community Violence Intervention And Prevention (Cvi): A Multi-State Policy Implementation Case Study, Sheetal Ranjan, C. Clare Strange, Katheryne Pugliese

Department of Justice Studies Faculty Scholarship and Creative Works

Background: Violence has fluctuated in the United States in recent years. Additionally, policing practices have been challenged, especially in neighborhoods of color. Community Violence Intervention (CVI) programs have emerged as an effective policy to address violence through neighborhood-centered resources, trauma-informed care, and credible messengers, without full reliance on law enforcement officials. However, inconsistent funding challenges the feasibility and sustainability of these programs. In 2021 several states introduced policies to allocate Medicaid reimbursement for CVI services offering a promising solution to a more sustainable stream of funding. Methods: This study uses rigorous qualitative analysis to evaluate the implementation of Medicaid reimbursement …


Sustainability Policy Proposals For The Township Of Montclair, Nj, Fanny Lauby, Josemy Barrera Cabal, Aaron Chauhan, Chase Geer, Carlos Jimenez, Catherine Khitiri, Jonathan Lockette, Andrew Mapes, Coral Mejía, Jack Nacht, Gabriella O’Keefe, Refia Oral, Sanjeev Rao, Jacob Roby, Julnide Saint Juste, Fiona Slatina Dec 2025

Sustainability Policy Proposals For The Township Of Montclair, Nj, Fanny Lauby, Josemy Barrera Cabal, Aaron Chauhan, Chase Geer, Carlos Jimenez, Catherine Khitiri, Jonathan Lockette, Andrew Mapes, Coral Mejía, Jack Nacht, Gabriella O’Keefe, Refia Oral, Sanjeev Rao, Jacob Roby, Julnide Saint Juste, Fiona Slatina

Department of Political Science and Law Faculty Scholarship and Creative Works

This white paper was written as a course requirement for POLS 324 Advanced Public Policy Analysis at Montclair State University in fall 2025. In the course, students analyze public policy and examine current issues. Public policy analysis can be defined as the development and evaluation of policy solutions to public problems. The course's learning objectives include “critically evaluate the goals and assumptions of different policy proposals,” “create a policy proposal for a public problem,” and “evaluate the proposals developed by their peers.” For the fall 2025 iteration of the course, I invited two offices in the township of Montclair to …


Empowerment Through Creating An Adaptive Sports And Recreation Program For Persons With Disabilities, Sarah Kadri, Angela Labrie Blackwell Dec 2025

Empowerment Through Creating An Adaptive Sports And Recreation Program For Persons With Disabilities, Sarah Kadri, Angela Labrie Blackwell

Fall 2025 OTD Capstone Symposium

Adaptive sports and recreation (ASR) refers to recreational and competitive physical activities modified to be inclusive and accessible for persons with disabilities (PWD), adjusting equipment, rules, instruction, and environmental setup to support participation across a wide range of physical, cognitive, and sensory abilities. PWD often report feeling disempowered due to social stigma, inaccessible environments, and limited opportunities to make meaningful choices about leisure and community life. A lack of diverse and consistent ASR opportunities within communities collectively hinders participation and negatively impacts overall well-being. Utilizing the Person Environment Occupation Performance (PEOP) theoretical framework, this capstone project developed a 10-week swimming …


Embodied Overcrowding And Sensory Tensions: A Carceral Autoethnography Of Philippine Jails, Dwayne Antojado Dec 2025

Embodied Overcrowding And Sensory Tensions: A Carceral Autoethnography Of Philippine Jails, Dwayne Antojado

Ateneo School of Government Publications

In this paper, I undertake a sensorially oriented autoethnography of two Philippine jails, illuminating the visceral textures of carceral life that conventional sociological or criminological discourses often overlook. Drawing inspiration from Jewkes and Young's (2021) examination of Kyoto Prison, I foreground the overlapping realms of sight, sound, smell, and touch, arguing that incarceration is inherently a profoundly embodied phenomenon. By weaving personal reflections, field observations, and broader scholarly insights, I reveal how overcrowded dormitories, suffocating heat, and lingering bodily odours converge to redefine detainees' spatial, temporal, and psychosocial realities in ways rarely captured by quantitative metrics. While mindful of Nelken's …


Title Page And Front Matter Dec 2025

Title Page And Front Matter

Michigan Journal of Public Health

No abstract provided.


Aged 539 Graduate Internship Report- Liberty High School, Brittany N. Johnson Dec 2025

Aged 539 Graduate Internship Report- Liberty High School, Brittany N. Johnson

Agricultural Education: Graduate Internship Reports

This document documents the AGED 539 Internship in Agricultural Education and examines the Liberty High School–Brentwood FFA and Agriculture Department’s alignment with the three-component model of agricultural education: classroom instruction, FFA leadership development, and Supervised Agricultural Experience (SAE). Grounded in experiential learning theory, the report reflects on program strengths, challenges, and growth across all twelve California Career Technical Education (CTE) Quality Criteria, supported by narrative reflection and evidence. The internship project focused on developing a formal FFA Program of Activities (POA) to improve chapter organization, goal-setting, and long-term sustainability. Overall, the project highlights intentional program planning and leadership development as …


The Lived Experiences Of School Counselors, Job Burnout, And The Blurred Lines Of The Profession, Cecilia Angelica Gomez Dec 2025

The Lived Experiences Of School Counselors, Job Burnout, And The Blurred Lines Of The Profession, Cecilia Angelica Gomez

Theses and Dissertations

This phenomenological qualitative study explores the lived experiences of school counselors during and after the COVID-19 pandemic, focusing on job burnout, role ambiguity, and the blurred lines of the profession. Through semi-structured interviews with practicing school counselors, the study identifies common themes including role overload, manifestations of burnout, coping and resilience strategies, and the impact of administrative support. Findings highlight the systemic factors contributing to counselor stress and the importance of self-care, peer collaboration, and role clarity for counselor well-being and student outcomes.


Resisting Facts Kills Jr, Maya Lakshmi Srinivasan, Special Collections, Fleet Library Dec 2025

Resisting Facts Kills Jr, Maya Lakshmi Srinivasan, Special Collections, Fleet Library

12th Baker & Whitehill Student Artists' Book Contest 2026

Entry for the 12th Baker & Whitehill Student Artists' Book Contest. Opening reception and award ceremony Wednesday, February 25, 2026 at 6:30pm, Fleet Library, 1st Floor Main Reading Room. Juror: Gabrielle Reed.


Preparing For “Disease X”: Lessons From Tax And Non-Tax Policy Responses To The Covid-19 Pandemic In Singapore And Australia, Vincent Ooi Dec 2025

Preparing For “Disease X”: Lessons From Tax And Non-Tax Policy Responses To The Covid-19 Pandemic In Singapore And Australia, Vincent Ooi

Research Collection Yong Pung How School Of Law

During the Covid-19 pandemic, a lack of pre-pandemic planning resulted in sub-optimal policy outcomes. Crucial lessons can be drawn from the experience of Singapore and Australia in the pandemic in implementing various tax and non-tax economic measures; lessons that can help in preparing for the next pandemic (“Disease X”). This article analyses and critically evaluates three main categories of economic measures: direct payments, tax measures and non-tax “other” measures. It finds that direct payment measures such as jobs support had a very significant impact on preserving jobs and supporting the economy. However, eligibility conditions have to be carefully designed for …


Happy Kids, Popular Kids? Life And School Satisfaction As Predictors Of Popularity In Early Adolescents, Chloe Mcbreen Dec 2025

Happy Kids, Popular Kids? Life And School Satisfaction As Predictors Of Popularity In Early Adolescents, Chloe Mcbreen

Theses/Capstones/Creative Projects

Sociometric popularity measures how well-liked a person is among peers. Life satisfaction has been positively related to self-perception and social functioning, whereas school satisfaction has been linked to stronger peer ties. This study examined how life and school satisfaction affected change in popularity over the course of a school year and how self-perception moderates said relationship. Participants included 182 fifth- and sixth-graders in Montreal, who completed 13 surveys over the school year. Popularity was measured via peer nominations at T1 and T13. Satisfaction variables and self-perception were measured via self-reports at T2 and T13, respectively. A hierarchical regression indicated that …


Protocol For Visual-Acoustic Intervention With Service Delivery In-Person And Via Telepractice (Visit) Non-Inferiority Trial For Residual Speech Sound Disorder, Tara Mcallister, Jonathan L. Preston, Elaine R. Hitchcock, Nina R. Benway, Jennifer Hill Dec 2025

Protocol For Visual-Acoustic Intervention With Service Delivery In-Person And Via Telepractice (Visit) Non-Inferiority Trial For Residual Speech Sound Disorder, Tara Mcallister, Jonathan L. Preston, Elaine R. Hitchcock, Nina R. Benway, Jennifer Hill

Department of Communication Sciences and Disorders Faculty Scholarship and Creative Works

Background: Residual speech sound disorder (RSSD) is a high-prevalence condition that negatively impacts social and academic participation. Telepractice service delivery has the potential to expand access to technology-enhanced intervention methods that can help remediate RSSD, but it is not known whether remote service delivery is associated with a reduction in the efficacy of these methods. This project will systematically measure the outcomes of visual-acoustic biofeedback intervention when delivered in-person or online. Methods/design: This project, Visual-acoustic Intervention with Service delivery In-person and via Telepractice (VISIT), aims to treat 76 children in a parallel randomized controlled clinical trial in which children with …


Road Surface And Subsurface Monitoring Using Machine Learning, Koduah Amoako Dec 2025

Road Surface And Subsurface Monitoring Using Machine Learning, Koduah Amoako

Theses and Dissertations

This thesis presents a comprehensive, non-invasive framework for real-time monitoring of road surface and subgrade conditions using acoustic sensing and machine learning. Traditional Tire-Road Coefficient of Friction (TRCF) estimation techniques often rely on intrusive sensors, offline data analysis, or laboratory measurements, making them impractical for real-time applications. The present research introduces an alternative approach that utilizes the acoustic emissions generated by tire-road interaction to infer both surface friction and subsurface integrity dynamically.Measurement microphones were mounted beneath a test vehicle to record tire-road noise signatures across different pavement textures and vehicle speeds. The collected acoustic signals were processed using Fast Fourier …


Resistance Through Policy: Documenting Lgbtq+ Advocacy In Public Education, Rhys Mitchell Fryar Dec 2025

Resistance Through Policy: Documenting Lgbtq+ Advocacy In Public Education, Rhys Mitchell Fryar

Theses and Dissertations

This research examines how educational policies related to LGBTQ+ students are constructed, interpreted, and implemented across federal, state, and district-levels. It asks whether institutional intent reflects authentic commitment to equity or functions as symbolic compliance in politically contested environments. Using Portland Public Schools (PPS) as a case study, the analysis situates the district within Oregon’s affirming policy landscape and the Trump administration’s restrictive federal mandates. PPS has adopted policies, such as Administrative Directive 4.30.061 AD (2023b) and the Gender Identity Support Guide (2023a), to support queer and gender-expansive students; however, it faces a federal investigation (U.S. Department of Education, 2025b, …


Cross Cancer Toxicogenomic Modeling Of Arsenic Exposure Identifies A Four Gene Signature For Lung Cancer Risk, Joshua Kennedy Dec 2025

Cross Cancer Toxicogenomic Modeling Of Arsenic Exposure Identifies A Four Gene Signature For Lung Cancer Risk, Joshua Kennedy

Theses and Dissertations

Arsenic is a naturally occurring carcinogenic element linked to DNA damage via reactive oxidation and epigenetic alteration that is ubiquitous throughout nature and has been associated with oncogenesis in the lungs, bladder, skin, and liver. Lung Cancer is both the most diagnosed cancer worldwide and the deadliest, comprising approximately 12.4% of all cancers globally and contributing to more human cancer death than any other condition, with roughly 90% of cases arising due to tobacco smoking, which exposes the user to arsenic trioxide and synergistic carcinogenicity when exposure includes both smoking and consumption of arsenic-contaminated drinking water. A novel set of …