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Articles 51121 - 51150 of 1791766
Full-Text Articles in Entire DC Network
Basic Effectiveness Of Group Mindfulness-Based Cognitive Therapy (Gmbct) In The University Setting, John Robert C. Rilveria, Nisseth Clarize S. Carido, April Veronica G. Lansangan, Alaya Gabrielle N. Villaflor, Anna Cristina A. Tuazon, Divine Love A. Salvador, Violeta V. Bautista
Basic Effectiveness Of Group Mindfulness-Based Cognitive Therapy (Gmbct) In The University Setting, John Robert C. Rilveria, Nisseth Clarize S. Carido, April Veronica G. Lansangan, Alaya Gabrielle N. Villaflor, Anna Cristina A. Tuazon, Divine Love A. Salvador, Violeta V. Bautista
Asia-Pacific Social Science Review
The COVID-19 pandemic has reshaped daily life and amplified mental health challenges worldwide, with university students identified as a particularly vulnerable group. To address this need, the present study evaluated the effectiveness of group mindfulness-based cognitive therapy (GMBCT) as an evidence-based intervention for students receiving psychosocial services during the pandemic. Using a pretest–posttest design, data from 34 students randomly assigned to either GMBCT or individual treatment-as-usual (TAU) provided by a university-based clinic were analyzed. To evaluate treatment effects, an analysis of covariance (ANCOVA) was conducted to compare post-treatment outcomes between the two groups while controlling for pre-treatment scores, treatment length, …
Exploring Societal Development: The Impact Of Social Innovation And Social Entrepreneurship - A Critical Review, Sneh Prabha, Satyaki Sarkar, Supriyo Roy
Exploring Societal Development: The Impact Of Social Innovation And Social Entrepreneurship - A Critical Review, Sneh Prabha, Satyaki Sarkar, Supriyo Roy
Asia-Pacific Social Science Review
In recent years, the emergence of social innovations and social entrepreneurship has dramatically influenced societal development. This paper explores the impact of synergizing social innovations and social entrepreneurship on various aspects of society, from economic policy to community resilience and societal development. Through a multidisciplinary lens, the research seeks an extensive review of social innovation and provides new solutions to entrenched social issues, whereas social entrepreneurship transforms these innovations into scalable initiatives that create meaningful change in society. While keeping traditional factors in mind, we explore the role of technology in developing new ways of working, the importance of collaboration …
Transient Neuromonitoring Changes And Delayed Vertebrobasilar Infarction Following Anterior Cervical Discectomy And Fusion: Illustrative Case, Jacob M. Chaisson, Jack A. Leoni, Ellery A. Hayden, Gabriel C. Tender, Amit K. Bhandutia
Transient Neuromonitoring Changes And Delayed Vertebrobasilar Infarction Following Anterior Cervical Discectomy And Fusion: Illustrative Case, Jacob M. Chaisson, Jack A. Leoni, Ellery A. Hayden, Gabriel C. Tender, Amit K. Bhandutia
School of Medicine Faculty Publications
BACKGROUND: Anterior cervical discectomy and fusion (ACDF) is a common spinal procedure with a well-established safety profile. While direct vertebral artery injury is rare and typically recognized intraoperatively, delayed posterior circulation stroke is an even less common but major complication. In patients with risk factors for vascular disease, vascular stress from surgical manipulation may predispose them to thromboembolic events that are not immediately apparent. Transient intraoperative neuromonitoring (IONM) changes may represent early, underrecognized indicators of such vascular compromise. OBSERVATIONS: The authors present the case of a 61-year-old male who underwent elective three-level ACDF for degenerative cervical myelopathy. During cage placement, …
Investigating Community Attachment, Quality Of Life, And Community Citizenship Behavior Toward Rural Tourism Development In Thailand, Supaporn Prasongthan, Pimonphat Rodtook, Jariya Supun, Rabhas Silpsrikul
Investigating Community Attachment, Quality Of Life, And Community Citizenship Behavior Toward Rural Tourism Development In Thailand, Supaporn Prasongthan, Pimonphat Rodtook, Jariya Supun, Rabhas Silpsrikul
Asia-Pacific Social Science Review
In rural tourism destinations, residents serve as representatives of the area, and their involvement in tourism and discretionary behavior contributes to the destination’s success. The objectives of this study were to explore the community citizenship behavior (CCB) model and to examine the relationship among residents’ attachment, quality of life (QOL), and five dimensions of CCB, including involving, keeping interpersonal harmony, protecting, helping, and recommending behavior, across two stages of rural tourism destinations in Thailand. A multivariate quantitative research method was employed. A total of 1,052 samples were retrieved from residents living in 10 selective rural tourism destinations, with 526 respondents …
The Economics Of Homelessness: A Quantitative Study On Homeless Willingness To Pay For Affordable Housing In Thailand, Peera Tangtammaruk, Nattapon Siwareepan, Jennifer Chavanovanich, Nartsupon Dumchuen, Thanee Chaiwat, Mattana Wongsirikajorn
The Economics Of Homelessness: A Quantitative Study On Homeless Willingness To Pay For Affordable Housing In Thailand, Peera Tangtammaruk, Nattapon Siwareepan, Jennifer Chavanovanich, Nartsupon Dumchuen, Thanee Chaiwat, Mattana Wongsirikajorn
Asia-Pacific Social Science Review
This study investigates the willingness to pay (WTP) for housing among homeless individuals in Thailand, using the contingent valuation method (CVM) and a structured choice experiment model. Data were collected through face-to-face interviews with 90 homeless individuals from Bangkok, Chiang Mai, and Khon Kaen. The study aims to understand the economic value that homeless individuals are willing to pay for various types of homelessness-related housing, as well as the factors influencing their WTP. The findings reveal that while most homeless individuals express a preference for affordable rental housing, their financial capacity remains limited due to low and unstable incomes. The …
Future-Ready Physicians: Exploring Medical Students’ Readiness, Attitudes, And Perceptions Of Healthcare Artificial Intelligence In Saudi Arabia, Hassan Abdulaziz Moria, Amirah Alatawi, Sharifah Alzahrani, Hyder Mirghani, Hisham Al Shadfan
Future-Ready Physicians: Exploring Medical Students’ Readiness, Attitudes, And Perceptions Of Healthcare Artificial Intelligence In Saudi Arabia, Hassan Abdulaziz Moria, Amirah Alatawi, Sharifah Alzahrani, Hyder Mirghani, Hisham Al Shadfan
Makara Journal of Health Research
Background: While the integration of artificial intelligence (AI) in healthcare has advanced globally, there is limited research on the preparedness of medical students in the Tabuk region of Saudi Arabia, particularly regarding their specific educational needs and cultural context. This study assessed medical students’ knowledge, attitudes, readiness, and confidence toward AI integration at the University of Tabuk, providing the first comprehensive analysis of AI readiness in this underrepresented northern region of Saudi Arabia.
Methods: A cross-sectional study was conducted among 261 medical students and interns across all academic years (1–6) at the Faculty of Medicine, University of Tabuk, …
Evaluating The Impact Of System, Information, And Service Quality On User Outcomes In Malaysian Public Hospitals: A Structural Equation Modeling Approach, Muhd Siv Azhar Merican Abdullah, Azimatun Noor Aizuddin, Mohd Rizal Abdul Manaf
Evaluating The Impact Of System, Information, And Service Quality On User Outcomes In Malaysian Public Hospitals: A Structural Equation Modeling Approach, Muhd Siv Azhar Merican Abdullah, Azimatun Noor Aizuddin, Mohd Rizal Abdul Manaf
Makara Journal of Health Research
Background: Increasing use of hospital information systems (HIS) underscores the need to evaluate their impact on User Satisfaction and Perceived Net Benefits. This study investigated the connections among outsourced System Quality, Information Quality, Service Quality, Perceived Usefulness, User Satisfaction, and Perceived Net Benefits in the context of Malaysian public hospitals.
Methods: Data were collected from 1,376 healthcare personnel across six public hospitals and analyzed using structural equation modeling through analysis of moment structures grounded in the DeLone and McLean Information Systems Success Model.
Results: System and Service Qualities significantly influenced User Satisfaction and Perceived Usefulness, while Information Quality impacted …
A Cross-Sectional Study On Patient Safety Attitudes And Their Determinants Among Medical Staff In Malaysian Public Specialist Hospitals, Sharifah Balqis Sayed Abdul Hamid, Aniza Ismail, Saperi Sulong
A Cross-Sectional Study On Patient Safety Attitudes And Their Determinants Among Medical Staff In Malaysian Public Specialist Hospitals, Sharifah Balqis Sayed Abdul Hamid, Aniza Ismail, Saperi Sulong
Makara Journal of Health Research
Introduction: This study aimed to assess the baseline level and mean scores of patient safety attitude domains among doctors and nurses in Malaysian public hospitals and to identify determinants associated with these attitudes across six domains: teamwork, safety climate, working conditions, job satisfaction, stress recognition, and perception of management.
Methods: A cross-sectional study was conducted using the Safety Attitudes Questionnaire (SAQ) among 142 doctors and 231 nurses from three public tertiary hospitals. Participants were selected through proportionate stratified random sampling. Data were analyzed using descriptive, bivariate, and multivariate methods.
Results: The study achieved an 81% response rate. …
Exploring The Prevalence And Determinants Of Self-Medication During Pregnancy Among Women From South Punjab, Pakistan, Madiha Madiha, Sehar Jabbar, Imran Masood
Exploring The Prevalence And Determinants Of Self-Medication During Pregnancy Among Women From South Punjab, Pakistan, Madiha Madiha, Sehar Jabbar, Imran Masood
Makara Journal of Health Research
Background: For developing countries with high neonatal and maternal mortality rates, any practice that may threaten the maternal-fetal health must be gauged. This study evaluated the prevalence and contributing factors of self-medication during pregnancy among women opting for antenatal or postnatal care in South Punjab, Pakistan.
Methods: A cross-sectional study design was used. Data was collected from 424 women, selected through multi-stage sampling, who visited health care facilities located in six randomly selected cities of South Punjab. Outcomes reported by descriptive and inferential statistics (p < 0.05). Binary logistic regression analysis was performed to determine the association of self-medication with different factors.
Results: Most of the women were involved in self-medication practice (38.9%) …
The Relationship Between Religious Attitude And Breastfeeding Attitude: A Cross-Sectional Study From Türkiye, Melike Yavaş Çelik, Cuma Tunçkaşık
The Relationship Between Religious Attitude And Breastfeeding Attitude: A Cross-Sectional Study From Türkiye, Melike Yavaş Çelik, Cuma Tunçkaşık
Makara Journal of Health Research
Background: This study aimed to evaluate the relationship between religious attitudes and breastfeeding attitudes and the effect of this relationship on breastfeeding practices.
Methods: This study was conducted with 203 mothers with babies aged 0–24 months. Simple random sampling was used in sample selection. The Religious Attitude Scale and Breastfeeding Attitudes of the Evaluation Scale were used in data collection.
Results: A significant relationship was found between religious attitudes and breastfeeding attitudes. Additionally, mothers' negative breastfeeding attitudes and positive breastfeeding attitudes were found to be close to each other. The time it took for mothers to start breastfeeding their …
Current Insight Into Ldlr And Pcsk9 Genetic Variants: Investigating Genetic Keys To Cholesterol In A Cohort Of Stroke Patients From Yogyakarta, Indonesia, Loury Priskila, Lenggana Relung Atmadi, Arya Taksya Bagaskara, Andreas Mercyan Anggitama
Current Insight Into Ldlr And Pcsk9 Genetic Variants: Investigating Genetic Keys To Cholesterol In A Cohort Of Stroke Patients From Yogyakarta, Indonesia, Loury Priskila, Lenggana Relung Atmadi, Arya Taksya Bagaskara, Andreas Mercyan Anggitama
Makara Journal of Health Research
Background: Stroke is the second leading cause of mortality worldwide. In Yogyakarta, Indonesia, the incidence of stroke (14%) is higher than the national average. We therefore investigated the roles of LDLR rs688 (C/T) and PCSK9 rs562565 (A/G) polymorphisms in familial hypercholesterolemia as predictors of first-time ischemic stroke.
Methods: In this case-control study, 119 first-time ischemic stroke patients were divided into dyslipidemia (N = 71) and non-dyslipidemia groups (N = 48). The DNA of the nucleotide polymorphisms LDLR rs688 (C/T) and PCSK9 rs562556 (A/G) was extracted and analyzed using the PCR-RFLP method, and statistical analyses were performed to evaluate …
Knowledge, Attitudes, And Practices Concerning Water, Sanitation, And Hygiene And Related Diseases Among University Students In Malaysia, Renee Ng Jeffrey, Aida Soraya Shamsuddin, Farah Diyana Ariffin, Aziemah Zulkifli
Knowledge, Attitudes, And Practices Concerning Water, Sanitation, And Hygiene And Related Diseases Among University Students In Malaysia, Renee Ng Jeffrey, Aida Soraya Shamsuddin, Farah Diyana Ariffin, Aziemah Zulkifli
Makara Journal of Health Research
Background: Water, sanitation, and hygiene (WASH) practices are fundamental components of public health, being crucial in preventing disease transmission and promoting healthy living environments. In this context, university students play an essential role as future professionals and community advocates in fostering proper hygiene behaviors and preventing disease outbreaks. Understanding knowledge, attitudes, and practices (KAP) in regard to WASH among individuals, particularly university students, is crucial for promoting proper hygiene behaviors. This study aimed to assess the KAP in regard to WASH and related diseases among undergraduate students from the Faculty of Health Sciences, Universiti Kebangsaan Malaysia (UKM).
Methods: …
Climate Change Anxiety Related To Women’S Health Among Health Sciences Students, Derya Kaya Şenol, Semiha Aydın Özkan, Durdu Cennet Omuş
Climate Change Anxiety Related To Women’S Health Among Health Sciences Students, Derya Kaya Şenol, Semiha Aydın Özkan, Durdu Cennet Omuş
Makara Journal of Health Research
Background: Climate change impacts are unequally distributed globally, with children, women, pregnant women, the elderly, marginalized populations, and refugees bearing a disproportionate burden. This study aims to determine the levels of related anxiety among female students and to examine the relationship between the anxiety and their perceptions, knowledge levels, and health behaviors related to women’s health.
Methods: The study has a descriptive cross-sectional design. The study population included women students enrolled in the fall semester of the 2023–2024 academic year at the Faculty of Health Sciences of a university between October and December 2023. Personal Information Form and …
Moving Toward Healthy Ageing: The Role Of Physical Activity In Cognitive Function And Self-Esteem Among Older Adults In Türkiye, Canan Birimoglu Okuyan, Müjde Kerkez
Moving Toward Healthy Ageing: The Role Of Physical Activity In Cognitive Function And Self-Esteem Among Older Adults In Türkiye, Canan Birimoglu Okuyan, Müjde Kerkez
Makara Journal of Health Research
Background: This study aimed to evaluate the relationship between religious attitudes and breastfeeding attitudes and the effect of this relationship on breastfeeding practices.
Methods: A cross-sectional study was conducted with 251 older adults. Data were collected using the International Physical Activity Questionnaire, the Standardized Mini-Mental State Examination, and the Rosenberg Self-Esteem Scale. Spearman’s correlation and chi-square tests were employed for statistical analysis.
Results: Physical activity levels were positively correlated with both cognitive function (r = 0.546, p < 0.001) and self-esteem (r = 0.168, p < 0.05). No significant association was observed between cognitive function and self-esteem. Physical inactivity, cognitive decline, and low self-esteem were more prevalent among women, participants with lower educational attainment, those with chronic diseases, and individuals engaged in polypharmacy.
Conclusions: The findings emphasize the importance of integrating physical activity promotion into national healthy ageing policies, particularly in Mediterranean contexts such …
The Relationship Between Individual Innovativeness Traits And Medical Artificial Intelligence Readiness Levels Among Nursing Students In Türkiye, Özlem Öztürk, Tülay Sağkal Midilli
The Relationship Between Individual Innovativeness Traits And Medical Artificial Intelligence Readiness Levels Among Nursing Students In Türkiye, Özlem Öztürk, Tülay Sağkal Midilli
Makara Journal of Health Research
Background: This study examined the relationship between nursing students’ individual innovativeness traits and their readiness for medical artificial intelligence, and the influencing factors.
Methods: This study was a descriptive, correlational study. The study was conducted with 606 nursing students enrolled at the Faculty of Health Science, Manisa Celal Bayar University. Data were collected using the Descriptive Information Form, the Individual Innovativeness Scale (IIS), and the Medical Artificial Intelligence Readiness Scale (MAIRS).
Results: The mean IIS score was 64.23 ± 8.47, indicating that most students fell into the skeptical or interrogator categories. The mean MAIRS score was 75.77 …
Understanding Parental Perceptions Of Truancy In Connecticut Youth: Identifying Risks And Prevention Strategies, Samantha Villa
Understanding Parental Perceptions Of Truancy In Connecticut Youth: Identifying Risks And Prevention Strategies, Samantha Villa
Honors Theses
This research investigates Connecticut parents' perspectives on effective strategies for addressing truancy. By examining stakeholder attitudes and beliefs, the study aimed to understand the relationship between perceptions of responsibility for truancy prevention and support for punitive versus non-punitive intervention approaches. In light of the COVID-19 pandemic's impact on truancy rates, current legislation and interventions have proven inadequate. This study assessed Connecticut adults' recommendations for truancy policy reforms and explored the potential for community-based interventions to enhance family engagement and reduce reliance on court involvement and punitive sanctions. IBM SPSS was used to analyze an existing dataset from the Tow Youth …
Effects Of Proactive Interference On Adults With Adhd: A Sex-Based Study, Julia Switzer
Effects Of Proactive Interference On Adults With Adhd: A Sex-Based Study, Julia Switzer
Honors Theses
ADHD is a widespread phenomenon that affects individuals in a variety of ways. Many individuals exhibit strong proactive interference, in which past memories interfere with the memorization and recall of new information. One of the ways symptoms differ is through the biological sex of individuals, although differences in proactive interference have not been studied in relation to sex. This study hypothesized that women with ADHD are better at resisting proactive interference than males with ADHD. The study involved a digital activity in which a series of colored shapes was shown to participants, who identified whether the previously displayed shapes or …
Race, Fear Of Falls, Built Environment And Physical Activity In Older Adults With Cancer, Kristen Fessele
Race, Fear Of Falls, Built Environment And Physical Activity In Older Adults With Cancer, Kristen Fessele
General Submissions: Community and Population-based Materials
Motivation for older adults with cancer (OAC) to engage in physical activity (PA) during and after cancer treatment may be limited by many factors. OAC may be affected by persistent symptoms limiting PA capability such as fatigue, pain and dyspnea, or lack safe home or neighborhood spaces to engage in activity. Fear of falling (FOF) is a major concern among OAC and may decrease PA and life-space mobility. To understand how OAC perceptions of cancer treatment, FOF and their local built environment (BE) influence PA behaviors, we partnered with ResearchMatch.org to recruit a sample of 19 people with a history …
Artificial Intelligence: A Double-Edged Sword In Support And Subversion Of The Biological Weapons Convention; Part Two: Implications And Recommendations, Diane Dieuliis, Elise Annett, James Giordano
Artificial Intelligence: A Double-Edged Sword In Support And Subversion Of The Biological Weapons Convention; Part Two: Implications And Recommendations, Diane Dieuliis, Elise Annett, James Giordano
Strategic Insights
This commentary is Pt. 2 of the "Artificial Intelligence: A Double-Edged Sword in Support and Subversion of the Biological Weapons Convention" series. This piece analyzes how artificial intelligence (AI) interacts with the Biological Weapons Convention (BWC) in both supportive and potentially adversarial ways. The authors explain that AI can strengthen biodefense by improving detection, biosurveillance, and compliance monitoring of biological threats. For example, AI can integrate large datasets to identify anomalies in genomic sequences or global research activity that indicate misuse. However, the same capabilities can be exploited to develop, conceal, and disseminate biological agents, automate laboratory processes that lower …
Achieving More Accurate And Interpretable Fraud Detection With Double Machine Learning, Jeremy Andrew Berry
Achieving More Accurate And Interpretable Fraud Detection With Double Machine Learning, Jeremy Andrew Berry
Theses and Dissertations
Fraud detection remains a critical challenge across industries such as insurance, healthcare, finance, and government. Global losses from fraud and financial crime are estimated in the trillions annually, including billions in healthcare and insurance fraud alone. While effective for prediction, traditional machine learning methods often lack causal interpretability and struggle to adapt to evolving fraud tactics. This dissertation investigates the application of Double Machine Learning (DML), an emerging causal inference technique, to enhance both the accuracy and interpretability of fraud analytics. The research compares DML against established causal inference approaches, leveraging a meta-learning framework to evaluate model performance on accuracy, …
Cv: Jung Kim (Literacy), Jung Kim
Cv: Jung Kim (Literacy), Jung Kim
Education Department Faculty Curricula Vitae
No abstract provided.
Replacement And Reputation, Navin Kartik, Elliot Lipnowski, Harry Pei
Replacement And Reputation, Navin Kartik, Elliot Lipnowski, Harry Pei
Cowles Foundation Discussion Papers
Does electoral replacement ensure that officeholders eventually act in voters’ interests? We study a reputational model of accountability. Voters observe incumbents’ performance and decide whether to replace them. Politicians may be “good” types who always exert effort or opportunists who may shirk. We find that good long-run outcomes are always attainable, though the mechanism and its robustness depend on economic conditions. In environments conducive to incentive provision, some equilibria feature sustained effort, yet others exhibit some long-run shirking. In the complementary case, opportunists are never fully disciplined, but selection dominates: every equilibrium eventually settles on a good politician, yielding permanent …
Violence Between Residents In Nursing Homes Is An Enduring Problem. The Agencies, Nursing Homes, And Residents Are Playing Hot Potato With The Responsibility, Cindy Marchionda, Rafael Escalara Montoto
Violence Between Residents In Nursing Homes Is An Enduring Problem. The Agencies, Nursing Homes, And Residents Are Playing Hot Potato With The Responsibility, Cindy Marchionda, Rafael Escalara Montoto
Capstones
Resident-to-resident aggression in nursing homes is a persistent issue, far more common than the general public realizes. While many of these violent situations can be managed, some tragically escalate to fatal outcomes, leaving families mourning the loss of their loved ones at the hands of a facility that was meant to provide safety and care during their final years. Experts agree that this issue is largely driven by chronic understaffing and insufficient training for employees on how to manage patients with dementia and aggression issues.
Suicidal Intentions Among Divorced Women In Wasit Province, Khitam Abbas Fadhel, Hassan Aii Ai-Sayed
Suicidal Intentions Among Divorced Women In Wasit Province, Khitam Abbas Fadhel, Hassan Aii Ai-Sayed
Alustath Journal for Human and Social Sciences
The current research aims to: Identifying Suicidal Intentions Among Divorced Women Marriage is viewed as a social institution that includes a set of norms regulating the relationship between spouses. The strength of this structure relies on solid foundations such as proper selection and compatibility in social aspects. Marriage imposes on spouses a set of mutual obligations and rights ensuring the continuity of marital life and enabling the family to fulfill its basic functions Despite the psychological, health and social significance marriage, offers to individuals and society, the phenomenon of divorce has been increasingly prevalent in recent times across various communities …
Integrating The Five As Framework To Enhance Person-Centered Care For Adults Living With Obesity, Alexandra Charles
Integrating The Five As Framework To Enhance Person-Centered Care For Adults Living With Obesity, Alexandra Charles
Electronic Theses and Dissertations
Obesity has adverse effects on physical health, emotional well-being, and mental functioning. To effectively address this highly prevalent and multifaceted condition, the use of a structured, evidence-informed framework is essential to support providers in delivering consistent, person-centered care for individuals living with obesity. The Five As is a powerful yet not commonly implemented framework in many primary care practices. The Five As framework (Ask, Assess, Advise, Agree, Assist) offers a structured model to guide clinicians in delivering consistent, supportive, and transformative care for individuals with obesity.
The goal of the project was to implement a timely and cost-effective protocol/tool that …
Low-Dimensional Signatures Of Neuronal Activity Associated With Long-Term Operant Conditioning In Aplysia, Sara Vanaki, Nicholas O Gonzalez, Curtis L Neveu, Yuto Momohara, Behnaam Aazhang, John H Byrne
Low-Dimensional Signatures Of Neuronal Activity Associated With Long-Term Operant Conditioning In Aplysia, Sara Vanaki, Nicholas O Gonzalez, Curtis L Neveu, Yuto Momohara, Behnaam Aazhang, John H Byrne
Faculty, Staff and Student Publications
Operant conditioning is a form of learning in which a behavior is reinforced by reward. Operant conditioning has multiple temporal domains, ranging from short-term, lasting a few minutes, to long-term, persisting for at least 24 h. The extent to which short- and long-term operant conditioning memories rely on shared or separate neural mechanisms is poorly understood. Voltage-sensitive dye (VSD) imaging has been used previously to record the activity of a large number of neurons simultaneously in the buccal ganglion to measure changes in neuronal activity during short-term operant conditioning. We examined neuronal activity using VSD 24 h after operant conditioning …
Working Paper No. 104, An Gorta Mór: The ‘Great Hunger’ And Irish Immigrant Labor In 19th Century America, Amanda Bergeson
Working Paper No. 104, An Gorta Mór: The ‘Great Hunger’ And Irish Immigrant Labor In 19th Century America, Amanda Bergeson
Working Papers in Economics
This inquiry seeks to establish that portions of the population of Ireland -- responding to what has been referred to in their Celtic language as An Gorta Mór, or in the English language as the ‘Great Hunger -- took to emigrating en masse and therewith contributed bigly to the expansion of America’s labor supply. Bolsterd by Irish immigrants, this expanding mid-nineteenth century labor force provided for an abundance of workers needed for a broadly based industrialization, that would also lead to large-scale urbanization as well as a host of changes in this nation’s social fabric. Of note is that …
Examining Religiosity, Suicidality, And Internalized Homonegativity Among Ethnoracially Diverse Sexual Minority Students, Danica Christy
Examining Religiosity, Suicidality, And Internalized Homonegativity Among Ethnoracially Diverse Sexual Minority Students, Danica Christy
UNLV Theses, Dissertations, Professional Papers, and Capstones
Sexual minority (SM) individuals are at an elevated risk for suicidality, particularly those who hold multiple marginalized identities, including religious and racial minority statuses. While religiosity is generally protective against psychological distress and suicide for heterosexual individuals, its impact on SM individuals is more complex. It may function as both a risk and a protective factor. The current mixed methods study explored the relationships between religiosity, internalized homonegativity (IH), and suicidality among an ethno-racially diverse sample of college students (n = 246). Quantitative analyses revealed that SM participants (n = 123) reported significantly higher rates of suicidality than their heterosexual …
Targeting Kinesin Family Member 20a Sensitizes Stem-Like Triple-Negative Breast Cancer Cells To Standard Chemotherapy, Yayoi Adachi, Weilong Chen, Cheng Zhang, Tao Wang, Nina Gildor, Rachel Shi, Haoyong Fu, Masashi Takeda, Qian Liang, Fangzhou Zhao, Hongyi Liu, Jun Fang, Jin Zhou, Hongwei Yao, Lianxin Hu, Shina Li, Lei Guo, Lin Xu, Ling Xie, Xian Chen, Chengheng Liao, Qing Zhang
Targeting Kinesin Family Member 20a Sensitizes Stem-Like Triple-Negative Breast Cancer Cells To Standard Chemotherapy, Yayoi Adachi, Weilong Chen, Cheng Zhang, Tao Wang, Nina Gildor, Rachel Shi, Haoyong Fu, Masashi Takeda, Qian Liang, Fangzhou Zhao, Hongyi Liu, Jun Fang, Jin Zhou, Hongwei Yao, Lianxin Hu, Shina Li, Lei Guo, Lin Xu, Ling Xie, Xian Chen, Chengheng Liao, Qing Zhang
Faculty, Staff and Student Publications
Triple-negative breast cancer (TNBC), being both aggressive and highly lethal, poses a major clinical challenge in terms of treatment. Its heterogeneity and lack of hormone receptors or HER2 expression further restrict the availability of targeted therapy. Breast cancer stem cells (BCSCs), known to fuel TNBC malignancy, are now being exploited as a vulnerability for TNBC treatment. Here, we dissected the transcriptome of BCSCs and identified kinesin family member 20A (KIF20A) as a key regulator of BCSC survival and TNBC tumorigenesis. Genetic depletion or pharmacological inhibition of KIF20A impairs BCSC viability and tumor initiation and development in vitro and in vivo. …
Itpr1 Autoantibody-Associated Autoimmunity As A Cause Of Newly Emerging Cognitive Decline Mimicking Alzheimer's Disease: Case Report And Brief Review Of The Literature, Nicolas Kunath, Hermod Arne Bollandsås Ramfjord, Elisabeth Volden Kvisvik, Marton Konyves-Kolonics, Gøril Rolfseng Grøntvedt, Irina I Serysheva, Lars Komorowski, Brigitte Wildemann, Sven Jarius
Itpr1 Autoantibody-Associated Autoimmunity As A Cause Of Newly Emerging Cognitive Decline Mimicking Alzheimer's Disease: Case Report And Brief Review Of The Literature, Nicolas Kunath, Hermod Arne Bollandsås Ramfjord, Elisabeth Volden Kvisvik, Marton Konyves-Kolonics, Gøril Rolfseng Grøntvedt, Irina I Serysheva, Lars Komorowski, Brigitte Wildemann, Sven Jarius
Faculty, Staff and Student Publications
Background: Since its first description in 2014, anti-inositol 1,4,5-trisphosphate receptor type 1 (ITPR1, also termed IP3R1) autoimmunity has been recognized as causing a clinically heterogeneous spectrum of symptoms. While first described in patients with autoimmune cerebellar ataxia, this facultative paraneoplastic disease has been associated also with peripheral neuropathy, dysautonomia, sleep disorders, neuropsychiatric/psychotic symptoms, and cognitive decline.
Methods: Retrospective case study.
Results: We report the case of a 58-year-old patient who was admitted with acute confusion, rapidly progressive cognitive decline, and hallucinations. A history of mild cognitive impairment over several years and low cerebrospinal fluid (CSF) amyloid beta-42 and elevated CSF …