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Dnp Final Report: Hypertension Education In The Primary Care Setting, Michelle L. Sanders

DNP Final Reports

Background: Hypertension is a significant concern at the global, national, and local levels. If left untreated or improperly managed, it can result in severe health issues. Many patients in primary care settings have difficulty controlling their hypertension, which can lead to significant complications.

Practice question: What strategies can be implemented to help patients in primary care manage their hypertension more effectively?

PICOT: For patients age 18+ in a rural primary care clinic (P), how does the use of an education pamphlet (I) compared to no pamphlet use (C) affect patient management of hypertension(O) in three months? (T)

Body of …

Microbial Communities Of Selected Regions Of The Deep Springs Lake Aquifer System, Rania Zaki, Emma Bourne, Andrew Storino, Jay Nadeau

Physics Faculty Publications and Presentations

Deep Springs Lake is a small, isolated, highly alkaline soda lake in Inyo County of Eastern California, USA. It is a seasonally filled salt lake or playa, and is part of a closed aquifer system. Such closed systems are globally rare, occurring only in arid zones where annual evaporation is greater than annual rainfall. Deep Springs Lake’s hydrology and geology have been well studied, and it is home to a unique toad species, but its microbiome remains unexplored. Here we perform 16S, 18S, and ITS amplicon sequencing of the lake water, dried salt crust at the edges the lake, and …

Beyond The Standard: A Sociolectal And Probabilistic Turn In Philippine English Phonology, Teri An Joy G. Magpale

Journal of English and Applied Linguistics

This article advocates for probabilistic approaches as a key framework for understanding Philippine English (PhE) phonology, arguing that they reveal socially conditioned variation that traditional descriptive models overlook. Tracing five decades of research, it critiques early standardization efforts and studies centered on scripted speech and elite norms, and highlights the sociolectal turn initiated by Tayao (2004). The discussion foregrounds recent methods that combine instrumental phonetics with constraint-based frameworks, including Optimality Theory (OT) and Maximum Entropy grammar (MaxEnt), to model gradient variation across acrolectal, mesolectal, and basilectal speakers. By synthesizing findings on segmental features, phonotactic patterns, and speech rhythm, the article …

The Relationship Between K-12 Public School Funding, Per Pupil Expenditures, And Student Achievement, Regina R. Frazier-Bagley

Walden Dissertations and Doctoral Studies

Public school district leaders are challenged with funding K-12 education that creates the desired student academic performance. Grounded in student-based budgeting theory, this quantitative ex post facto study aimed to investigate the relationship between K–12 public school funding, per-pupil expenditures, student achievement, and graduation rates in Georgia. The study included secondary data from 51 North Georgia public school districts for the 2018–2019 school year. Multiple regression analysis was completed to examine the relationship between the independent variables—state funding, per-pupil expenditures, and academic achievement in math, science, and language arts—and the dependent variable: graduation rates. The results of the analysis were …

Reducing The Use Of Erythropoiesis-Stimulating Agents In Hemodialysis Patients, Myriamme Neree

Walden Dissertations and Doctoral Studies

This Doctor of Nursing Practice project was a quality improvement (QI) initiative. Nephrologists were inconsistent in ordering iron studies and sometimes delayed the initiation of erythropoiesis-stimulating agents (ESAs) on admission to the inpatient site. These delays often led to suboptimal outcomes. The practice-focused question guiding the project asked whether a nurse-driven iron protocol would improve adherence to anemia management guidelines. The project’s purpose was to evaluate the impact of the evidence-based nurse-driven protocol. I used descriptive and inferential statistics for data analysis. Findings demonstrated a statistically significant improvement in the timely completion of iron studies and in intravenous (IV) iron …

Recruitment, Retention, And Retirement Plan Structure: Evidence From Teachers, Noah Burke, Brock Wilson

ISER Reports

In 2006, the State of Alaska closed its defined benefit retirement plan and required all newly hired public education employees—mostly teachers—to join a defined contribution plan. This paper examines whether that change in pension structure affected recruitment or retention in Alaska’s public education workforce.

Using Overcoming Obstacles Curriculum To Improve Social Emotional Skills In Elementary Students, Tessa Lynne Large

Dissertations, Theses, and Projects

Social emotional learning (SEL) skills are important for children for success in schools as they have been shown to improve academics, and success in life. Children can struggle with SEL skills for a variety of reasons. SEL programs in schools are designed to help improve skills such as self-awareness, self-management, social awareness, relationship skills, and responsible decision making. The purpose of this study was to investigate the use of a SEL curriculum, Overcoming Obstacles, to improve SEL skills in three 1^st grade students. These students were identified as needing extra support with following schoolwide expectations. This intervention was implemented …

Osteoprogenitor Cells From Non-Regenerative Bone Show Greater Resistance To Cellular Stress Than Those From Regenerative Bone, Joshua Broussard, Sylvia Culpepper, Tyrel Long, Alexander J. Trostle, Robert J. Tower, Mimi C. Sammarco, Jennifer Simkin

School of Medicine Faculty Publications

INTRODUCTION: Bone regeneration following injury depends on osteoprogenitor cells derived predominantly from the periosteum. Incomplete regeneration has been attributed to both cell-extrinsic factors (e.g., environment, inflammation, mechanical instability) and cell-intrinsic factors (e.g., impaired proliferation or differentiation of stem cells). In the digit amputation mouse model, amputation through the third phalanx (P3) supports complete regeneration, while amputation through the second phalanx (P2) results in callus formation and scarring. Periosteal cells are known to be the major contributing cell source for repair and regeneration. Yet the healing outcomes of P2 and P3 amputations are significantly different. This study tests whether P2 and …

Endocrine Disrupting Chemicals And Adrenal Gland​, Gülay Şi̇mşek Bağir, Melek Eda Ertörer

Turkish Journal of Medical Sciences

Endocrine disrupting chemicals (EDCs) are exogenous compounds that have hormone-like effects inside the body. Endocrine disruptors can affect adrenal glands in humans and animals. Adrenocortical dysfunction related to chemical exposure has been reported in the literature.The human adrenal gland is crucial for the synthesis of steroid hormones (glucocorticoids, mineralocorticoids, and androgens) and amino acid-derived hormones (epinephrine and norepinephrine). All steps in the adrenocortical steroidogenesis pathway are potential targets for chemical inhibition, including the adrenocorticotropic hormone receptor, steroidogenic acute regulatory protein, mitochondrial cytochrome P450 (CYP) enzymes (CYP11A1, CYP17, CYP21, CYP11B1, and CYP11B2), and 3-hydroxysteroid dehydrogenase D4,5 isomerase. EDCs either inhibit the …

Endocrine-Disrupting Chemicals In Metabolic Bone Diseases, Including Osteoporosis, Betül Gündüz, Eli̇f Kiliç Kan, Ayşegül Atmaca

Turkish Journal of Medical Sciences

Endocrine disruptors are chemical substances widely utilized across various industrial sectors. Due to their structural similarity to natural ligands, they bind to receptors and influence the endocrine system via agonist–antagonist mechanisms. Exposure occurs through the consumption of contaminated food and water, inhalation of polluted air and dust, and dermal contact. Owing to their dynamic remodeling capacity, bones represent potential targets for endocrine-disrupting chemicals. These chemicals can disrupt bone formation, skeletal development, hormonal regulation, and calcium metabolism. Sensitivity to endocrine-disrupting chemicals is greatest during the prenatal and early postnatal periods. This review summarizes the effects of endocrine-disrupting chemicals on bone tissue.

Biotechnology In The Fy 2026 Ndaa: Strategic Implications — And Recommendations — For Joint Force Readiness, James Giordano

Strategic Insights

This commentary analyzes how biotechnology provisions in the FY 2026 National Defense Authorization Act (NDAA) reflect emerging opportunities and challenges for U.S. national security. It explains that key investments in bioindustrial capacity, synthetic biology, bioinformatics, and related research signal a strategic shift toward integrating biological technologies into defense planning. While these advancements can strengthen biodefense, medical readiness, and operational resilience, they also raise policy, ethical, and governance questions about prioritization, oversight, and risk management. Dr. Giordano offers practical recommendations, including the need for enhanced workforce education, robust interdisciplinary coordination, and international collaboration to ensure responsible innovation. Aligning biotechnology investment with …

Targeting Pancreatic Cancer With Rapamycin-Loaded Gold Nanoparticles Conjugated To Egf Peptide: Studies On Cytotoxicity And Uptake Mechanisms Aided By Proteomic Analysis, Adeolu Oluremi

Theses and Dissertations

Pancreatic cancer remains one of the most lethal malignancies, with a five-year survival rate below 5%. While rapamycin (Rap) has demonstrated therapeutic potential, its clinical utility is hampered by systemic toxicity. To address this limitation, this study developed a targeted nanocarrier system using gold nanospheres (AuNPs) functionalized with the Epidermal Growth Factor Receptor (EGFR) peptide GE11 for the specific delivery of Rap to pancreatic cancer cells. It is to note that pancreatic cancer overexpresses EGFR. The AuNP–GE11–Rap conjugates were successfully synthesized and characterized using physico-chemical techniques, which confirmed peptide conjugation and drug loading. In vitro studies using PANC-1 cells demonstrated …

Effects Of Pamam Dendrimer Size On Antimicrobial Activity For Acne Treatment, Elise M. Inae

Honors Theses

This study investigated the antimicrobial activity of G1, G2, and G3-Hex-NH2 polyamidoamine (PAMAM) dendrimers with an emphasis on how dendrimer size influenced their efficacy against C. acnes and S. epidermidis. Dendrimers are nano-sized, radially symmetric polymers composed of highly branched units that extend out from a central core. Dendrimers are known to exhibit antimicrobial activity against Gram-negative bacteria by disrupting the lipid bilayer and causing membrane damage. This study explored their effect on a different group of microorganisms–Gram-positive skin flora. Kirby-Bauer disk diffusion tests were performed to evaluate minimum inhibitory concentrations for each dendrimer solution. All generations of PAMAM dendrimers …

Urinothorax And Empyema: Presentation Of An Unusual Complication Of A Rare Condition, Nolan Fox, Nicholas Fox, Shourjo Chakravorty, Neeraj Sinha

Division of Pulmonary, Allergy, and Critical Care Medicine Faculty Papers

A 68-year-old male with a history of metastatic bladder cancer and urinary obstruction presented with intractable hiccups and chest pain is presented in this case. He was found to have a unilateral pleural effusion in addition to ipsilateral renal metastasis abutting the diaphragm. Imaging revealed empyema. Thoracentesis revealed positive cultures and a lack of malignant cells on cytology. Comorbid urinary obstruction and urinary tract infection suggested the rare diagnosis of an infected urinothorax. Thoracentesis also revealed pleural fluid creatinine greater than serum creatinine, meeting the most specific diagnostic criteria for urinothorax and establishing the diagnosis. Treatment aimed at evacuating the …

Student Voices On Trauma And Resilience: A Critical Phenomenological Study Of Gun Violence And College Student Experiences, Lucia Helena Garcia

Dissertations

This study posits that gun violence in the United States is a public health crisis and that colleges and universities must actively collaborate to develop and implement solutions to address and prevent this crisis, which affects communities and students. Gun violence can and does lead to disruptions in educational access, travel and safety, as well as have longstanding impacts on mental health. While extensive research exists that is focused on the impact of community and gun violence exposure on K-12 students, the impact of community violence and gun violence exposure on emerging adults in university settings is limited and remains …

Teaching And Learning With Feeling: A Qualitative Case Study Of Teacher Candidates’ Experiences With Socio-Emotional Learning, Anna Melinda Press

Dissertations

Research on socio-emotional learning (SEL) has demonstrated its many benefits for students, justifying its prevalence in pre-kindergarten to grade 12 schools across the U.S. Despite evidence of the centrality of a teacher’s role in effective SEL implementation, less research has been conducted on teacher training in SEL – particularly for teacher candidates (TCs). The purpose of this qualitative case study was to examine TCs’ experiences with SEL, and the impact of those experiences on their development as providers of SEL. Purposive sampling was used to recruit TCs in either the second or third year of one specific undergraduate, field-based teacher …

Documents From The December 17th, 2025, Meeting Of The University Of Montana Staff Senate., University Of Montana--Missoula. Staff Senate

University of Montana Staff Senate Meeting Minutes

Agenda and meeting minutes from the December 17th, 2025 meeting of the University of Montana Staff Senate
Highlights include new Secretary nomination, Heart of the Grizzly Logo, and Goals for the New Year.

Hydrodynamic Contrast Recanalization-Facilitated Rotational Atherectomy To Treat A Heavily Calcified Coronary Chronic Total Occlusion, Som P Singh, Mustafa Al Qaysi, Angelo Nascimbene, Mauro Carlino, Salman A Arain

Faculty, Staff and Student Publications

BACKGROUND: Percutaneous coronary intervention (PCI) for heavily calcified chronic total occlusion (CTO) remains among the most challenging procedures in interventional cardiology. Hydrodynamic contrast recanalization (HDR) is a novel crossing technique for CTO that uses intraplaque contrast microinjections in the proximal CTO to facilitate the passage of polymer jacketed wires. The use of HDR combined with rotational atherectomy (RA) during CTO PCI in heavily calcified arteries has not been described.

CASE SUMMARY: A 72-year-old man with refractory angina was referred for revascularization of a chronically occluded ramus intermedius. The presence of heavy calcium and flush occlusion of the left main artery …

Clinical Outcomes Of Patients With Unsuccessful Mechanical Thrombectomy Versus Best Medical Management Of Medium Vessel Occlusion Stroke In The Middle Cerebral Artery Territory, Tobias D Faizy, Vivek Yedavalli, Hamza Adel Salim, Dhairya A Lakhani, Basel Musmar, Nimer Adeeb, Muhammed Amir Essibayi, Motaz Daraghma, Kareem El Naamani, Nils Henninger, Sri Hari Sundararajan, Anna Luisa Kuhn, Jane Khalife, Sherief Ghozy, Luca Scarcia, Leonard Ll Yeo, Benjamin Yq Tan, Robert W Regenhardt, Jeremy Josef Heit, Nicole M Cancelliere, Aymeric Rouchaud, Jens Fiehler, Sunil A Sheth, Ajit S Puri, Christian Dyzmann, Marco Colasurdo, Leonardo Renieri, João Pedro Filipe, Pablo Harker, Răzvan Alexandru Radu, Mohamad Abdalkader, Piers Klein, Thomas R Marotta, Julian Spears, Takahiro Ota, Ashkan Mowla, Pascal Jabbour, Arundhati Biswas, Frédéric Clarençon, James E Siegler, Thanh N Nguyen, Ricardo Varela, Amanda Baker, David Altschul, Nestor Gonzalez, Markus A Möhlenbruch, Vincent Costalat, Benjamin Gory, Christian Paul Stracke, Constantin Hecker, Gaultier Marnat, Hamza Shaikh, Christoph J Griessenauer, David S Liebeskind, Alessandro Pedicelli, Andrea Maria Alexandre, Illario Tancredi, Erwah Kalsoum, Max Wintermark, Boris Lubicz, Aman B Patel, Vitor Mendes Pereira, Adam A Dmytriw, Adrien Guenego, Mad-Mt Investigators

Faculty, Staff and Student Publications

Background: Current randomized controlled trials are investigating the efficacy and safety of mechanical thrombectomy (MT) in patients with medium vessel occlusion (MeVO) stroke. Whether best medical management (MM) is more efficient than unsuccessful vessel recanalization during MT remains unknown.

Methods: This was a retrospective cohort study using data from 37 academic centers across North America, Asia, and Europe between September 2017 and July 2021. Only patients with occlusion of the distal branches (M2 and M3) of the middle cerebral artery territory were included. Unsuccessful MT was defined as a modified Thrombolysis in Cerebral Infarction score of 0-2a. Propensity score matching …

Differences In Lactation Curve Parameters And Milk Yield Responses Between Artificially Induced And Naturally Calved Cows Milked In An Automatic Milking System, Marcos Busanello

Turkish Journal of Veterinary & Animal Sciences

Despite advances in artificial induction of lactation (AIL) protocols, they do not perfectly mimic the hormonal patterns of natural pregnancy. Recent studies show improved milk yield (MY) responses; however, comparisons of lactation curve parameters between AIL and naturally calved (NC) cows often do not extend beyond 305 days in milk (DIM). Thus, this study aimed to compare MY responses and lactation curve parameters between AIL and NC cows milked in an automated milking system (AMS). Data from 38 Holstein cows (19 AIL and 19 NC) were analyzed, focusing on the 305 DIM period. Wood’s lactation curve model was used to …

Cover And Contents

Turkish Journal of Veterinary & Animal Sciences

No abstract provided.

Antimicrobial Sensitivity Of Bacterial Isolates And Molecular Detection Of Staphylococcus Aureus And Staphylococcus Pseudintermedius Isolated From Urinary Tract Infections Of Canines, Mankaran Kaur, Gursimran Filia, Ashok Kumar

Turkish Journal of Veterinary & Animal Sciences

Urinary tract infections (UTIs) are commonly encountered in canine clinical cases and can result in significant health complications if not properly treated. This study isolated and identified bacterial pathogens from dogs with clinical signs of UTI. Antimicrobial susceptibility profiling was performed on the bacterial isolates and further molecular detection of Staphylococcus aureus and Staphylococcus pseudintermedius was also performed. A total of 104 urine samples were collected via cystocentesis and catheterization. Bacterial identification was conducted using standard bacteriological procedures, and antimicrobial susceptibility was assessed using the disc diffusion method with 21 different antimicrobial discs. Polymerase chain reaction (PCR) was used for …

Evaluation Of Blood-To-Fluid Gradient Of Glucose And Lactate As Biomarkers In The Early Diagnosis Of Septic Peritonitis In Dogs, Silpa Sn, Sujata Turkar, Neetu Saini, Sushma Chhabra, Kuldip Gupta, Gursimran Filia

Turkish Journal of Veterinary & Animal Sciences

Septic peritonitis is a serious, life-threatening condition with a high mortality rate. Accurate diagnosis is crucial for the survival of the affected animal. The present study analyzed the use of a blood-to-fluid gradient of glucose and lactate as a biomarker in the diagnosis of septic peritonitis. Thirteen dogs with septic peritonitis and nine dogs with aseptic peritonitis were included in this study. Blood-to-fluid glucose gradient was significantly high, and blood-to-fluid lactate gradient was significantly low in septic peritonitis compared with the aseptic peritonitis. A blood-to-fluid glucose gradient of ≥12 mg/dL showed 100% sensitivity and 55.6% specificity, whereas a blood-to-fluid lactate …

Determination Of The Cecal Microbiota Profile Of Anadolu-T Broiler Breeder Chickens Using 16s Metagenomic Sequencing, Kürşat Teti̇k, İsmai̇l Özkan, Serpi̇l Kahya Demi̇rbi̇lek

Turkish Journal of Veterinary & Animal Sciences

The gut microbiota has significant effects on the performance, health status, and immune systems of chickens. The complex microbial community structure begins to form after chicks hatch with the intake of feed, water, and air into the digestive system. Disrupting the balance of this system can lead to the proliferation of pathogenic microorganisms. Until recently, studies on microbiota relied on traditional microbiological techniques that cultured only a small fraction of the microbial diversity. However, significant advancements in DNA sequencing and bioinformatics have enabled the identification of diverse bacterial populations in environmental samples. In this study, a total of 2000 broiler …

Parameter Optimization For Runs Of Homozygosity (Roh) Detection In The Pig Genome, Timofey Romanets, Anna Korobeynikova, Lyubov Getmantseva, Maria Kolosova, Elena Romanets, Ilona Bakoeva, Varvara Shevtsova, Anatoly Kolosov, Alexander Maksimov, Siroj Bakoev

Turkish Journal of Veterinary & Animal Sciences

The present study analyses the influence of various parameters on the accuracy and reliability of ROH identification procedures, as well as their relationship with inbreeding and genetic diversity in Duroc pig populations. The genotyping data of 70 Duroc pigs obtained using PorcineSNP80v1 chips were used, and the effects of LD pruning and ROH calling parameters were evaluated. It was found that the use of strict basic filters during the execution of the --homozyg command reduces the likelihood of false positives and contributes to the more accurate identification of ROH. The results show that LD pruning reduces the detection of random …

Determination Of Serum Cortisol Levels As A Stress Marker In Hospitalized Dogs, Emre Tüfekçi̇, Gencay Eki̇nci̇, İlknur Karaca Bekdi̇k, Ali̇ Cesur Onmaz, Öznur Aslan, Vehbi̇ Güneş, İhsan Keleş, Mehmet Çi̇ti̇l

Turkish Journal of Veterinary & Animal Sciences

In veterinary medicine, various diseases and surgical procedures may require the isolation and hospitalization of dogs, allowing for more effective individual patient monitoring and increasing the chance of successful treatment by preventing unnecessary drug use. However, this process can be stressful. Our study aimed to determine the changes in cortisol levels, one of the primary stress hormones responsible for stress responses, in individually hospitalized dogs. In addition, epinephrine (EPN) levels, another stress marker, as well as hematological and some biochemical values were measured and vital signs were recorded. The dogs included in the study were divided into 3 groups: healthy, …

The Influence Of Endocrine Disrupters On Gut Microbiota, Kader Ugur

Turkish Journal of Medical Sciences

Endocrine disruptors (EDs) are closely associated with the second brain, the microbiota-derived enteric nervous system, commonly referred to as the gut microbiota. The microbiota plays a crucial role in human health and the development of diseases. In today’s industrialized world, the presence of EDs in air, water, and soil leads to primary human exposure through dermal contact and ingestion. The impact of these EDs on the microbiota remains unclear. EDs that disrupt the balance of the gut microbiota may contribute to a range of disorders, including metabolic (obesity, diabetes mellitus), cardiovascular (vascular stenosis, cerebrovascular disease), reproductive (infertility, ovarian and testicular …

Endocrine-Disrupting Chemicals And Thyroid Cancer, Özge Baş Aksu, Mustafa Şahi̇n

Turkish Journal of Medical Sciences

Environmental endocrine-disrupting chemicals (EDCs) have emerged as a critical global health concern because of their role in various diseases, including thyroid cancer. Defined as exogenous substances that disrupt endocrine system functions, EDCs can affect multiple generations through mechanisms such as hormone receptor modulation, altered hormone synthesis, and epigenetic modifications.The increasing global incidence of thyroid cancer has heightened interest in environmental factors, with EDC exposure recognized as a significant contributor. Compounds such as heavy metals, persistent organic pollutants, per- and polyfluoroalkyl substances, and bisphenol A play crucial roles in disrupting thyroid homeostasis. Emerging evidence underscores the synergistic effects of multiple EDC …

Effects Of Endocrine Disruptors On The Neurological System, Kadi̇rcan Karatoprak, Soner Cander

Turkish Journal of Medical Sciences

Background/aim: There is increasing interest in endocrine disrupting chemicals because of the potential effects on neurological health. These chemicals are widely found in various consumer products and industrial processes, and can lead to serious disorders of the endocrine system by disrupting hormone synthesis, expression, and function. The aim of this review was to examine epidemiological and experimental findings by investigating the link between exposure to endocrine disrupting chemicals and adverse neurological outcomes.

Materials and methods: In the preparation of this review, a PubMed literature search was conducted using the words “endocrine disruptors,” “neuroendocrine effects,” “neurobehavioral effects,” and “neurodevelopmental effects” and …

Endocrine Disruptors And Pregnancy, Betül Yi̇ği̇t Yalçin, Gamze Bi̇li̇k Oyman, Ayşe Kubat Üzüm

Turkish Journal of Medical Sciences

Sensitivity to endocrine disruptors is higher in early life. In pregnant women, endocrine disruptor chemicals can be passed to the baby through the placenta or through breast milk during lactation, leading to long-term and permanent adverse effects. These endocrine disruptors may cause adverse effects in women such as infertility, implantation defects, premature birth, spontaneous abortions, gestational hypertension, gestational diabetes. Exposure to endocrine disruptors in the intrauterine period may result in adverse effects on the reproductive system, metabolic changes, low birth weight, retardation in mental and physical development and also may be associated with congenital malformations. It is of great importance …