Digital Commons Network^™

The Placenta & Covid-19: Histological Changes & Clinical Implications, Melissa F. Paul, Allyson J. Zadlo Sensor

All Electronic Theses and Dissertations

Introduction: The COVID-19 pandemic presented the medical community with complex and novel challenges, not the least of which is how to optimize prenatal and postnatal care for pregnant individuals who have been infected. At present, seven years have elapsed, and despite definitive research demonstrating adverse outcomes associated with placental changes, no professional consensus has been reached.
Methods: This integrative review includes studies involving pregnant individuals with confirmed SARS-CoV-2 infection, who recovered during the same pregnancy, and their infants. An examination of the data available reveals a triad of placental pathologies (chronic histiocytic intervillositis, perivillous fibrin deposition, and trophoblast necrosis) that …

Supporting Sustainable Art Education: How School Structures Influence Creativity, Michelle Schutz

All Electronic Theses and Dissertations

This study examines how structural conditions within schools influence sustainable teaching practices in visual arts education. Specifically, it explores how class schedules, preparation time, and administrative support shape teachers’ ability to implement creativity-centered instruction aligned with the demands of artistic learning. Drawing on a qualitative synthesis of existing research on instructional time, organizational structures, and educational leadership, this study identifies key patterns in how school systems support or constrain meaningful visual arts instruction. Findings indicate that structural factors, rather than individual teacher characteristics, play a central role in shaping instructional quality and sustainability. Limited instructional time, fragmented scheduling models, insufficient …

Ai Literacy Frameworks In Secondary Cte: Supporting The Next Generation Of The Workforce, Reagan Kaylee Montross

All Electronic Theses and Dissertations

The purpose of this literature review is to understand how generative AI (GenAI) is impacting the future employment of high school students at the forefront of the most significant technological, cultural, and educational shift of this generation. It examines five AI literacy frameworks relating to secondary education. These frameworks each emphasize the importance of educating students in AI literacy and provide educators with a structure for integrating AI skills. Among the frameworks reviewed, those published by the United States Department of Labor and the OECD place greater emphasis on applied practices, while the AI4K12 and KAT frameworks emphasize how AI …

How Gender Differences Influence The Presentation, Diagnosis, And Lived Experience Of Females With Autism Spectrum Disorder, Casey A. Vanyo

All Electronic Theses and Dissertations

Autism spectrum disorder (ASD) is a neurodevelopmental condition with a highly variable presentation influenced by gender. Historically, autism research has focused primarily on males, contributing to the under recognition and misdiagnosis of girls, women, and gender-diverse individuals. Women engage in camouflaging behaviors to align with social expectations, which can mask autistic traits and contribute to higher levels of anxiety, depression, and emotional exhaustion. This thesis examines how gender shapes the presentation, diagnosis, and lived experiences of autistic females. It explores differences in diagnostic practices, mental health outcomes, and access to support. Findings suggest that current frameworks often fail to capture …

Statins For Primary Prevention Of Variceal Bleeding In Cirrhosis: A Scoping Review, Jason Brumitt

Faculty Publications - College of Physical Therapy

Background/Objectives: Variceal bleeding (VB) is a major complication of cirrhosis, marking a progression from a compensated to a decompensated stage of the disease. Previous research has suggested that HMG-CoA reductase inhibitors, commonly called statins, may have therapeutic benefits for those living with cirrhosis, though their exact benefits and role have yet to be elucidated. This scoping review evaluates the potential role of statins in the primary prevention of variceal bleeding in patients with cirrhosis, and if there exists a difference between hydrophilic and lipophilic statins for this indication. Methods: Publications from the last 10 years with primary or secondary outcomes …

Validity Of The Promis Ability To Participate In Social Roles And Activities Measure In Older Adult Health Assessment, Theresa Raudsepp

Faculty Publications - College of Physical Therapy

Objective: The International Classification of Function is often used in older adult clinical assessments. Well recognized is the high value, and difficulty, of assessing participation in social roles. The PROMIS Ability to Participate in Social Roles (APSR) measure may augment assessments enhancing our understanding of older adults’ participation in social roles. The purpose of this study was to examine whether the APSR diverges with other clinical measures suggesting it is measuring a separate construct adding new information to the clinical assessment.

Methods: A sample of convenience of older adults (n = 89) was recruited and administered clinical assessments that include …

Evaluation And Enhancement Of Suspected Opioid Overdose Definitions In Emergency Medical Services Data Using Machine Learning With Natural Language Processing, Peter Rock, Svetla Slavova, Sharon L. Walsh, Julia Martin, Daniel R. Harris

Institute for Biomedical Informatics Faculty Publications

Background: Fatal and non-fatal drug overdoses have evolved into a critical public health crisis, with over a 50% increase in the rate of fatal drug overdose since 2019. Emergency Medical Services (EMS) data has advantages over traditional emergency department data, including timeliness and captured non-transport encounters. However, there is no consensus EMS definition for suspected opioid overdose (SOO), and currently implemented knowledge-based (KB) definition may miss ambiguous cases. Machine learning with natural language processing (ML-NLP) has the potential to enhance SOO identification.

Methods: Secondary data originated from an oversampled dataset of 2,327 weighted encounters from Kentucky State EMS data (2018–2022). …

Evaluation Of The Healthy Eating And Recovery Together (Heart) Digital Health Intervention To Support Head And Neck Cancer Caregivers And Survivors, Katherine R. Sterba, Jessica L. Burris, Rong Duan, Benjamin A. Toll, Kent Armeson, Christina Sithideth, Bhishamjit Chera, Kenneth Ruggiero, Evan M. Graboyes

Psychology Faculty Publications

Background: Head and neck cancer (HNC) survivors and their caregivers face significant challenges at the end of treatment and interventions are critically needed to support their needs. The Healthy Eating and Recovery Together (HEART) intervention includes a needs assessment and tailored care plan for dyads and an application (App) for caregivers. The objectives of this trial were to evaluate the feasibility, acceptability, and short-term effects of HEART on unmet needs and depression in HNC survivors and caregivers.

Methods: In a single arm clinical trial, HNC caregivers and survivors (n=23 dyads) completed baseline surveys followed by an in-person or virtual HEART …

Ai Washing And The Federal Government: How Government Agencies Can Address Risks Posed By The Growing Prevalence Of Artificial Intelligence In The Corporate Sphere, Sheheryar A. Khan

Student Works

No abstract provided.

Generative Imaging For Computational Pathology, Md Jillur Rahman Saurav

Computer Science and Engineering Dissertations

Hematoxylin and eosin (H&E) staining remains central to cancer diagnosis, providing morphological information essential for pathological assessment. Immunohistochemistry (IHC) and newer multiplexed imaging technologies complement H&E by revealing molecular information critical for accurate tumor subtyping and treatment decisions. In practice, however, H&E and IHC are obtained from different consecutive sections that are not spatially aligned, comprehensive multiplexed panels are expensive and tissue-consumptive, and not all stains are available at every clinical site, limiting comprehensive molecular profiling and the full diagnostic potential of these technologies in clinical practice. This dissertation addresses these gaps through three complementary generative deep learning studies in …

Should The Illiberal Arts Be Servile In A Classical Christian Education, Nadine B. Kong Mrs.

Master of Arts in Classical Studies

The purpose of this thesis is to research the role and position of the illiberal arts in a classical Christian education (CCE).  The current climate of growth for CCE makes it a fitting moment to consider what bearing the illiberal arts should have on paideia formation.  To answer this question, the historical context of CCE and the illiberal arts is presented.  This leads to a complex issue around the various imprecise terms and historical attitudes surrounding the illiberal arts.  Some synonymous terms have demeaning connotations: ‘servile arts’ or ‘illiberal arts,’ and others less negative, such as ‘common arts’ or ‘mechanical …

Multimodality Proposal, Academic Affairs

Executive Actions

No abstract provided.

Litigating The "Forever Chemical" Problem Through The Endangered Species Act, Charlotte A. Ramirez

Emory Law Journal

Per- and polyfluoroalkyl substances (PFAS), a class of man-made, resiliently bonded chemicals, cause harm to both humans and animals. These “forever chemicals” can compromise immunity, increase cancer risks, and cause reproductive harm. Addressing the harms caused by PFAS variants is crucial to protect public health, environmental health, and biological diversity. However, the United States’ current regulatory scheme takes a disjointed approach to PFAS regulation. This is complicated by the frequent development of new PFAS variants, whose effects and environmental presence are largely unknown and understudied. While even the protections provided for humans under the current regulatory scheme fall short of …

Techno-Optimism In Innovation Law And Policy, Peter Lee

Emory Law Journal

This Article examines an underappreciated bias that has long pervaded U.S. legal culture: an exceedingly enthusiastic view of technology and technological progress. It adopts the term “techno-optimism” to describe an asymmetrically positive view of innovation that extols its benefits, minimizes its harms, and elides much of its complexity. The recent rise of more skeptical attitudes toward technology only casts into sharper relief the techno-optimism that has subtly dominated policy debates for decades. As a case study of techno-optimism, this Article scrutinizes patent law, particularly its constitutionally defined objective of promoting technological progress. In so doing, it offers the first extended …

Addiction To Constitutionally Protected Activity: Speech, Press, And Religion, Eugene Volokh

Emory Law Journal

Recent statutes and lawsuits have sought to restrict social media or video game design practices that supposedly cause some users to become “addicted.” Are such restrictions consistent with the First Amendment?

This Article begins by asking what would happen if the same arguments were applied to religious practices (whether or not the arguments’ supporters would seek to so apply them). Say some religious practice was viewed as causing emotional or financial harm—e.g., by leading some adherents to feel guilty about their sexuality, to distance themselves from family members, or to give substantial portions of their assets to the religious organization. …

Mindfulness Practice And Increases In Gray Matter Density, Gray Matter Volume, And Cortical Thickness: A Scoping Review, Jason Brumitt

Faculty Publications - College of Physical Therapy

Background/Objectives: Mindfulness-based interventions (MBIs) have been linked to psychological and cognitive benefits, yet evidence for their impact on brain structure remains sparse. Neuroimaging suggests MBIs may alter gray matter volume (GMV), density (GMD), and cortical thickness (CT). The purpose of this scoping review was to investigate structural neuroplasticity following MBIs. Methods: Following PRISMA-ScR guidelines, databases were searched for studies published between 2010 and 2023 that used structural MRI to assess structural brain changes in subjects after receiving MBIs. Nine studies met inclusion criteria, including five randomized controlled trials. Results: Mindfulness interventions ranged from 10 h of training to long-term practice …

The Effect Of Gratitude On The Mental Health Of Healthcare Workers As Measured By Burnout And Depression, Jason Brumitt

Faculty Publications - College of Physical Therapy

Burnout and depression have been considered long-standing issues among healthcare workers worldwide. Current interventions for managing poor mental health include exercise, medical treatments, mindfulness, and workplace changes. The practice of gratitude has shown significant improvements in mental health in the general population, and it has been proposed as a potential intervention for healthcare workers. This scoping review aimed to assess the effect of gratitude on the mental health of healthcare workers as measured by burnout and depression. The Cumulative Index to Nursing and Allied Health Literature and Medical Literature Analysis and Retrieval System Online databases were searched using medical subject …

The Nevada Plan: Redefining The Bar In The Silver State, Grace Michaelson

Nevada Law Journal Forum

Nevada is rewriting the rules of entry into its legal profession. In 2024, the Nevada Supreme Court approved plans for a new state bar exam that will take effect in 2027. The new format, known as the Nevada Plan, significantly departs from Nevada’s traditional bar exam and fundamentally alters the licensure process for those aspiring to practice law in the Silver State. This Note will explore the proposed changes and their implications through three main sections. Part I provides essential context for understanding the current moment in bar exam reform. It begins by examining the traditional role of bar exams …

Communication Studies Minor, Communication And Journalism

Program Revisions/Additions

No abstract provided.

287(G) Or Not 287(G)? That Is The Question: Nevada’S Role In Regulating Local-Federal Cooperation On Immigration Enforcement, Zachary Sweetin, Elizabeth Swenson

Nevada Law Journal Forum

This White Paper aims to examine the authority of local agencies and institutions in Nevada to enter into cooperative 287(g) agreements with ICE without state approval. Part I provides an overview of the history and structure of 287(g) agreements, including the recent adoption of this cooperative model by four Nevada jurisdictions. This Paper will also explore sections of Nevada Re- vised Statutes that may affect the legality of 287(g) agreements, focusing in Part II on Nevada’s modified Dillon’s Rule and in Part III on Nevada Revised Statutes (NRS) 228.206. Using pending American Civil Liberties Union of Nevada (ACLU) litigation against …

Exploring Relational Farming Futures For Responsible Innovation In Precision Agriculture Through Q-Method And Speculative Design, Bhavna Joshi, Maaz Gardezi, Edward Prutzer, Awais Hameed Khan, Asim Zia, Benjamin E. K. Ryan, Ali Dadkhah, Donna M. Rizzo, John T. Mcmaine, David Clay

Biosystems and Agricultural Engineering Faculty Publications

This article draws on concepts of speculative design and responsible innovation to examine the possible impacts of data-driven precision agriculture on farmers and farm work. We use an innovative mixed-method approach to research design. Using artistic depiction of futures of precision agriculture in design workshop and in-depth semistructured interviews conducted with the farmers in Vermont and South Dakota, we explain how farmers perceive different futures of precision agriculture. Specifically, in our design workshop, we combined visual arts and social science methods, namely Q-method, to explore existing and new relationships between humans, technologies, and environment in the design, deployment, and use …

The Influence Of Adverse Childhood Experiences On Female Violent Offending: A Scoping Systematic Review, Alexis M. Wolgemuth

Theses, Dissertations and Capstones

Female-perpetrated violence has exhibited concerning data trends in recent years. Prior scholarship indicates that past victimization and trauma in childhood, known as adverse childhood experiences (ACEs), are highly prevalent among women offenders. However, the research concerning ACEs and violent females is scattered. This thesis provides a scoping literature review using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) updated 2020 guidelines. A systematic database search was conducted using Academic Search Complete, SAGE Journals, Springer Nature Link, and HeinOnline to identify relevant peer-reviewed journal articles. Inclusion and exclusion criteria are established, focusing on studies published after January 2015. These …

Improving Data Collection And Analysis For Development Of An Ai Powered Video Based Autism Screening Tool, Angelica Sanyal, Ziteng Wang

CURE Proceedings

No abstract provided.

Temporal Evolution Of Brain Inflammation In The Bilateral Common Carotid Artery Stenosis Model Of Chronic Cerebral Hypoperfusion, Makayla F. Cox, Jill M. Roberts, Ryan K. Shahidehpour, David L. Dornbos Iii, Adam D. Bachstetter

Neuroscience Faculty Publications

Chronic cerebral hypoperfusion is a major contributor to vascular cognitive impairment and dementia, primarily through its disruption of white matter integrity and promotion of neuroinflammatory cascades. The bilateral common carotid artery stenosis (BCAS) model has emerged as the predominant experimental approach for studying the effects of chronic cerebral hypoperfusion, particularly in aging-relevant contexts. This review synthesizes current knowledge of inflammatory responses in the BCAS model, with an emphasis on their temporal progression and functional consequences. We begin by outlining the clinical burden of hypoperfusion, the rationale for BCAS, and the hemodynamic phases it produces. We then examine early neurovascular unit …

Dim Light At Night Impacts Circadian Rhythms And Alzheimer’S Disease-Like Neuroinf Lammation And Neuropathology In Humanized App Saa Knock-In Mice, Marilyn J. Duncan, Margaret R. Hawkins, Leke Bytyqi, Haleigh R. Whitlock, Savannah M. Shepard, Makayla F. Cox, Esther G. Drinkard, Teresa Macheda, Kelly N. Roberts, Katharina Kohler, Mary-Claire Schmidt, Carrie E. Johnson, Sridhar Sunderam, Bruce F. O'Hara, Michael Paul Murphy, Adam D. Bachstetter

Neuroscience Faculty Publications

Artificial light at night (light pollution) is widespread but understudied in the context of Alzheimer’s disease (AD). Sleep and circadian disruption have been linked to amyloid-β (Aβ) accumulation and neuroinflammation, but whether dim light at night (dLAN) modifies these processes remains unclear. We tested whether chronic dLAN exposure (8 lux during the dark phase, 8 weeks) alters circadian rhythms, amyloid pathology, and neuroinflammation in 12–13 month-old humanized APP knock-in (KI) mice. hAPP^SAA KI mice, which develop plaques, were compared with hAPP^WT KI controls carrying only a humanized APP sequence. dLAN reduced circadian rhythm amplitude and stability while increasing …

A Descriptive Study Of Culturally Responsive Practices In Positive Behavioral Interventions And Supports (Pbis) In West Virginia Elementary Schools, Janna Rae Coleman

Theses, Dissertations and Capstones

This descriptive mixed-methods study examined elementary teachers’ implementation and perceived effectiveness of culturally responsive practices within existing Positive Behavioral Interventions and Supports (PBIS) systems in a West Virginia school district. Guided by Leverson et al.’s (2021) Culturally Responsive PBIS (CRPBIS) framework, the study explored five components of culturally responsive practice: identity, voice, supportive environment, situational appropriateness, and data for equity. Both quantitative and qualitative data were collected from 86 elementary teachers using the researcher-developed Culturally Responsive Practices in Existing PBIS Survey. Findings indicated that teachers reported frequent implementation and perceived effectiveness across all five components, with the supportive environment receiving …

Endocranial Morphological Affinities Of The Early Holocene Individuals From Lagoa Santa And Implications For The Peopling Of The Americas, María Clara López-Sosa, Hugo Reyes-Centeno, Lumila Paula Menéndez, Rodrigo Elias Oliveira, Claudio Campi De Castro, André Strauss

Anthropology Faculty Publications

The ectocranial morphology of early Holocene humans from Lagoa Santa, Brazil has been described as exhibiting a ‘Paleoamerican’ form with affinities to African and Australasian individuals, in contrast to past and present Native Americans, who predominantly exhibit ‘Amerindian’ form. While this interpretation remains disputed, its led to the ‘Two Main Biological Components Model’, which proposes separate dispersals from Asia into the Americas. This study aims to assess whether the endocranial morphology of Lagoa Santa individuals similarly reflects these affinities. For this study, the overall endocranial morphology, as well as the temporal bones of the crania of twenty individuals from Lagoa …

Walking The Line How Social Forces Shape Diabetic Foot Outcomes In The Texas Rio Grande Valley, Amanda L. Killeen, Stephanie N. Campbell, Naomie Jean, Juan Lopez-Alvarenga, Xuan Wang, Cyaandi Dove, Caroline E. Fife

School of Podiatric Medicine Publications

• Diabetes in the Rio Grande Valley is widespread and severe. Nearly 1 in 3 adults is affected, with foot ulcers and amputations occurring at rates far above state and national averages.
• Social drivers of health (SDOH) strongly influence outcomes. Poverty, uninsurance, limited education, transportation barriers, and distance from specialty centers delay care and increase amputation risk.
• Living conditions amplify risk. Colonias, unincorporated settlements often lacking clean water, sewer systems, or reliable electricity, make diabetes management and preventive foot care especially challenging.
• Data-driven identification of high-risk populations is critical. Zip code–level SDOH data, integrated into electronic medical records, can serve as …

Carrots, Not Sticks: A Contingency Management Model For Rural Methamphetamine Recovery, Ella House

Scripps Senior Theses

Rates of methamphetamine use disorder (MUD) have risen sharply across the United States, with rural Appalachia experiencing the steepest mortality increases. Contingency management (CM) is among the most effective treatments for stimulant use, yet implementation is constrained by cost, logistics, and clinician shortages. Utilizing digital CM platforms and peer recovery support specialists, who are central to addiction support in rural regions, may reduce these barriers. This thesis proposes a 16-week, three-arm randomized controlled trial (N ≈ 300) comparing: (1) Digital Abstinence CM Only (remote saliva toxicology and monetary vouchers for stimulant-negative tests); (2) Digital + Peer-Goal CM (digital abstinence-based CM …

Who We Are Together: Identity Negotiation In Different-Orientation Relationships, Justin Tackett

Theses, Dissertations and Capstones

viii Abstract This qualitative study explored how partners in different-orientation (dif-orientation) relationships experienced and navigated identity across the five frames of the Communication Theory of Identity (CTI): personal, enacted, relational, communal, and material. Dif-orientation relationships, romantic partnerships where individuals identify with different sexual orientations, represent a form of intercultural communication involving partners from distinct sexual orientation communities who must negotiate different cultural frameworks regarding sexuality, relationships, and identity expression. Despite growing recognition of diverse relationship configurations, little research currently examines how partners in these relationships manage identity gaps, or misalignments between different frames of identity, and what communication strategies they …