Digital Commons Network^™

From Crisis To Courtroom: The Unstoppable Journey Of Jarrett Brown, January 30, 2026, Tisa Mason Ed.D.

Heart of a Tiger Columns

No abstract provided.

Perancangan Microblog Instagram Sebagai Media Promosi Untuk Meningkatkan Brand Awareness Nawspaper.Co, Nawang Cahyani, Dhara Alim Cendekia

Journal of Language, Literature, and Arts

Nawspaper.co is an Indonesian sticker shop brand that adopts K-pop as its main theme and targets a specific market segment, namely K-pop fans and journaling hobbyists. As a newly established brand in an industry dominated by numerous competitors, Nawspaper.co faces intense competition, particularly in terms of visual presentation on social media platforms. Therefore, an effective promotional strategy is required to increase brand recognition among the target audience and potential consumers. Microblog design was selected as the primary promotional medium due to its high potential for engagement and wide dissemination on social media. This design project applies the Design Thinking method …

The Correlation Between The Frequency Of Using Grammarly And The Accuracy Of Students’ Thesis Writing, Tri Herawati, Suharyadi Suharyadi, Harits Masduqi

Journal of Language, Literature, and Arts

Grammar-checking tools have gained popularity as a means of addressing writing difficulties and improving students’ writing quality, particularly grammatical accuracy. Therefore, it is important to examine the relationship between the frequency of Grammarly use and the accuracy of students’ thesis writing to understand the potential benefits and limitations of Grammarly as a writing tool in academic contexts. This study aimed to investigate whether a correlation exists between these two variables. A quantitative approach with correlational research design was employed. The participants were 63 English Language Education students from Universitas Negeri Malang who were enrolled in the 2017, 2018, and 2019 …

Two Lysosomal Genes Atp13a2 And Gba1 Interact To Drive Neurodegeneration, Mingxue Gu, Jinghan Zhao, Mingxi Deng, Guang Lin, Xueyang Pan, Wenwen Lin, Mengqi Ma, Jinyong Kim, Seul Kee Byeon, Akhilesh Pandey, Lara M Lange, Chad A Shaw, Jonggeol Kim, Joanne Trinh, Christine Klein, Oguz Kanca, Joshua M Shulman, Hugo J Bellen

Duncan NRI Faculty and Staff Publications

Background: Parkinson’s disease (PD) is a genetically complex disorder in which combinations of heterozygous risk variants may contribute to pathogenesis. Many PD risk loci encode lysosomal genes, such as GBA1, a common and potent risk factor, conferring at least a 5-fold increase. However, the mechanisms of GBA1 penetrance remain poorly understood.

Methods: Using Drosophila melanogaster, we performed a genetic interaction screen of lysosomal storage disorder (LSD) genes to identify dominant modifiers of Gba1b (fly homolog of GBA1). Age-dependent locomotor assessments, electroretinograms (ERG), transmission electron microscopy (TEM) analyses and quantification of dopaminergic (DA) neurons were used to assess …

A Heterogeneous Population Code At The First Synapse Of Vision, Tessa Herzog, Takeshi Yoshimatsu, Jose Moya-Diaz, Ben James, Leon Lagnado, Tom Baden

2020-Current year OA Pubs

Vision begins when photoreceptors convert fluctuations in light intensity into temporal patterns of glutamate release that drive the retinal network. The input-output relation at this first stage has not been studied in vivo so it is not known how it operates across a photoreceptor population. Using glutamate imaging in zebrafish, we find that individual type 1 cones (PR1; ancestral red cones), which dominate daylight vision in non-avian vertebrates, encode visual stimuli with high reliability and time-precision but routinely vary in sensitivity to luminance, contrast and frequency across the population. Variations in input-output relations are generated by feedback from the horizontal …

Rapid Diagnosis Of Staphylococcus Aureus Using The Lamp Method, Hadeel Abdul-Amir, Thair Al-Kelabi

AUIQ Conference Proceedings

Methicillin-resistant Staphylococcus aureus (MRSA), a genetically distinct strain of S. aureus, poses a significant health problem in humans and animals. MRSA is responsible for various difficult-to-treat illnesses in humans and animals. The loop-mediated isothermal amplification (LAMP) experiment was performed using four unique primers developed for six distinct mecA and femA gene sequences. The LAMP test was completed in 45 minutes at 62.5°C and visualized by gel electrophoresis. Moreover, the LAMP test has better sensitivity than conventional PCR, detecting genomic DNA at 64.8 pg/μL, which is hundreds of times more sensitive than conventional PCR.  The LAMP test is an …

Defective Viral Genomes: Emerging Therapeutic Tools For Animal Viral Infections, Saad Hashem Ghmeiss, Ali Abdul-Jassim Alwan

AUIQ Conference Proceedings

Defective Viral Genomes (DVGs), which are viral genomes that are defective in some way, are naturally occurring byproducts of viral replication in numerous RNA viruses, notably Orthomyxoviridae (Influenza virus), Filoviridae (Ebola and dengue), and Paramyxoviridae (Respiratory Syncytial). They have three well-defined functions: interference with regular virus replication, immunostimulation, and virus persistence. DVGs are defective viral genomes that can hijack the replication cycle of wild-type viruses, leading to partial or complete suppression of viral populations. A variety of new DVGs are created through infection of the host by one of these viruses. The researchers devised a strategy for identifying those most …

Spontaneous Simultaneous Bilateral Intraparenchymal Hemorrhage In A Child With Sickle Cell Disease, Adelaide Valluzzi, Julian S. Rechberger, Elena Millesi, Corrado Iaccarino, Lucio Lucchesi, Giovanni Palazzi, Francesca Cavalleri, Giacomo Pavesi

Journal of Pediatric Neurology

No abstract provided.

Novel Variants In Jam3 Gene- A Rare Cause Of Early Onset Cns Hemorrhage - First Case Report From India With Review Of Literature, Ashka Prajapati, Manaswini Manaswini, Parth Shah, Nidhi Shah

Journal of Pediatric Neurology

This study provides a systematic review of optic neuritis and neuroretinitis associated with cat scratch disease (CSD) caused by Bartonella henselae. CSD, commonly transmitted through cat scratches or bites, can lead to visual complications, particularly in children, who are more frequently exposed to cats. A comprehensive literature search identified 10 relevant studies from an initial pool of 521 articles. Typical CSD manifests with regional lymphadenopathy, but severe complications like hepatosplenomegaly and encephalitis can occur, especially in younger patients. Atypical presentations, such as neuroretinitis, often begin as optic neuritis with papillary edema, progressing to a macular star pattern. Pediatric patients may …

Acute Non-Traumatic Tetraplegia Secondary To Thiamine Metabolism Dysfunction Syndrome-2: Case Report, Lisandra Coneglian De Farias Rigoldi, Mara Lucia Schmidt Ferreira Santos, Andressa Taine Szczypkovski, Mônica Alexandra De Conto, Suelen Dos Santos Henrique, Bruno Augusto Teles, Daniel Almeida Do Valle

Journal of Pediatric Neurology

Introduction: Acute non-traumatic tetraplegia is an infrequent presentation in the pediatric emergency department, with thiamine metabolism dysfunction syndrome (TMDS) representing an even rarer cause. This article aims to report a case of acute and transient non-traumatic tetraplegia secondary to TMDS. Case Report: A previously healthy 1-year-and-3-month-old girl, with expected neurodevelopment was admitted with an acute onset of flaccid paraplegia, progressing to spastic tetraplegia. Initial laboratory tests were unremarkable. Cranial magnetic resonance imaging revealed changes in the basal ganglia, manifested as bilateral and symmetrical oval hypodensities with increased areas of permeation cavitation. Proton spectroscopy showed no clear lactate peak, indicative of …

Optic Neuritis And Neuroretinitis In Cat-Scratch Disease: An Updated Systematic Review, Sara Urdiales-Sánchez, José-Ramiro González-Montaña, Pilar Alonso-Alonso, Javier Urdiales-Urdiales

Journal of Pediatric Neurology

This study provides a systematic review of optic neuritis and neuroretinitis associated with cat scratch disease (CSD) caused by Bartonella henselae. CSD, commonly transmitted through cat scratches or bites, can lead to visual complications, particularly in children, who are more frequently exposed to cats. A comprehensive literature search identified 10 relevant studies from an initial pool of 521 articles. Typical CSD manifests with regional lymphadenopathy, but severe complications like hepatosplenomegaly and encephalitis can occur, especially in younger patients. Atypical presentations, such as neuroretinitis, often begin as optic neuritis with papillary edema, progressing to a macular star pattern. Pediatric patients may …

Interview With Priscilla Hodgkins

Creative Nonfiction Magazine

No abstract provided.

Cover To Cover: Reviews Of New Books, Larry Bielawski, Ronald Dahl, David Hayes, Lea Simonds

Creative Nonfiction Magazine

No abstract provided.

Musselshell, Robert Coker Johnson

Creative Nonfiction Magazine

No abstract provided.

Pilot Study: Role Of Social Support And Stress On Anxiety In First-Year College Students, Erin N. Smith, Deven L. Dancy, Lauren E. Nee, Kali Rebuck, Stephanie J. Shirk

Journal of Applied Disciplines

Research indicates worsening mental health, especially anxiety, in college populations; yet few studies have investigated anxiety and related factors in this population. This study examined the impacts and interrelations among anxiety, stress, and social support in first year, first semester college students. In a sample of 119 students, the following models of the impact of social support in the stress-anxiety relation were tested: 1) a direct impact of social support, 2) a moderating effect of social support, and 3) an indirect impact of social support. Results indicated that the indirect model of the influence of social support best fit the …

Comorbidity Of Cerebral Palsy And Bipolar Disorder In Two Adolescents: Case Series, Ayda Beril Nas Ünver, Merve Onat, Esra Çöp

Journal of Pediatric Neurology

Cerebral palsy (CP) is a common condition in children that affects movement and posture due to non-progressive disruptions during cerebral development. Patients with CP are at a higher risk of developing mental health disorders due to social and physical factors. 28%–57% of children diagnosed with CP exhibit psychiatric diagnoses or symptoms. The symptoms of intellectual disability and related behavioral disorders that are often associated with cerebral palsy can be easily confused with the symptoms of a mood disorder. Therefore, there is a possibility of a delay in the diagnostic procedure and the commencement of treatment, which could potentially endanger the …

Psychological Factors And Family Communication In Children And Adolescents With Elimination Disorders, Mehdi Ebrahimi, Hossein Mousavi Nasab, Mehrdad Hosseinpour, Noshirvan Khezri Moghadam

Journal of Pediatric Neurology

Background: Elimination disorders, such as urinary (enuresis) and fecal incontinence (encopresis), involve inappropriate voiding beyond the expected age due to developmental, psychological, or physiological factors. These conditions impact children’s emotional well-being, self-esteem, social functioning, and family relationships. However, few studies have compared psychological functioning and family communication in affected children. This study examines general health, behavioral problems, and mother-child relationships in children with elimination disorders versus healthy peers. Methods: Seventy-two children participated: 25 with urinary incontinence, 24 with fecal incontinence, and 23 healthy controls. Participants were recruited from hospitals in Isfahan. Data were collected using standardized questionnaires: the General Health …

Adolescent-Onset Leigh Syndrome Associated With Homozygous Ndufv1 C.640g>A (P.E214k) In Low-German Mennonites Of Southwestern Ontario, Prashanth Rajasekar, Chitra Prasad, Victoria Mok Siu, Charles Anthony Rupar, Asuri Narayan Prasad

Journal of Pediatric Neurology

Objective: Leigh syndrome, formerly known as infantile subacute necrotizing encephalomyelopathy, is a progressive neurometabolic disorder characterized by midbrain and brainstem lesions leading to rapid neurodegeneration. Pathological variants in over 80 nuclear encoded genes, predominantly affecting respiratory chain and energy metabolism proteins, have been implicated in Leigh syndrome. This paper aims to provide an overview of current understanding of Leigh syndrome, emphasizing clinical, pathological, and molecular genetic aspects, with a specific focus on a novel finding of adolescent onset Leigh syndrome associated with variant c.640G>A identified among Low German-speaking Mennonite families in Southwestern Ontario. Methods: We present a case series …

An Album Quilt, John Mcphee

Creative Nonfiction Magazine

No abstract provided.

Original Friend, Donald Morrill

Creative Nonfiction Magazine

No abstract provided.

Transit, K.E. Ellingson

Creative Nonfiction Magazine

No abstract provided.

Opsoclonus In Children: Diagnosis, Etiology And Ophthalmologic Assessment Of Patients At A Tertiary Children’S Hospital, Melissa Yuan, Jacqueline Jeon-Chapman, Tais Estrela, Ryan Gise

Journal of Pediatric Neurology

Introduction: Opsoclonus is often associated with serious neurologic and paraneoplastic pathology. Pediatric ophthalmologists play an important role in its diagnosis. Methods: Retrospective chart review of patients seen for suspicion of opsoclonus. Results: 259 patients were identified for whom opsoclonus was suspected, of which 83 (32%) were found to be true opsoclonus. The ophthalmology consultation changed the course of workup in 44 of the 117 patients that received ophthalmologic evaluation (38%). 16 (9%) were found to have primary ophthalmic diagnoses. Of the 83 children with opsoclonus, 36 (43%) had paraneoplastic opsoclonus-myoclonus-ataxia syndrome (OMAS), 32 (39%) had non-paraneoplastic OMAS, 1 (1.2%) had …

A June Journal, David Gessner

Creative Nonfiction Magazine

No abstract provided.

I Thought I Heard Buddy Bolden Say, Brenda Marie Osbey

Creative Nonfiction Magazine

No abstract provided.

Primary Amoebic Meningoencephalitis (Pam) With Progression To Brain Death Following Naegleria Fowleri Infection In A Teenage Female, Samantha Brener, Stephen Schaffner, Ingrid Y. Camelo, Hasan Samra, Renuka Mehta

Journal of Pediatric Neurology

Background: Naegleria fowleri is a high-temperature freshwater-living amoeba causing PAM by invading nasal epithelium. N. fowleri lives ubiquitously in high-temperature freshwater, but only around 400 cases of PAM have been published worldwide. The mortality rate is 98%. No treatment is 100% effective. Case Presentation: A previously healthy 17-year-old female presented to an urgent care center with fever, headache, sore throat, ear pain, and dizziness. She had swum in freshwater 5 days prior. Her symptoms progressed to altered mental status, photo- and phonophobia, and neck stiffness. Within 4 days, she developed increased intracranial pressure (ICP) and eventually brain death. Two unsuccessful …

Examining Neural Correlates Of Sexual Preferences Between Persian Homo- And Heterosexual Males Using Psychological Assessments And Functional Magnetic Resonance Imaging In Specifying Cognitive Map: A Limited And Cross-Sectional Study, Abdollah Khorshidi

Journal of Pediatric Neurology

Although the brain is an important part of a person’s sexual life, little is known about the correlations between sexual response and brain activation. This study examines brain response through clinical testing to reveal a number of brain structures whose activation are relevant to sexual arousal besides psychological testing according to the common traditional values and standards of Iranian society. Based on initial self-report, 25 homosexual and 25 heterosexual males participated in this test to elucidate the identity and sexual trends via Minnesota Multiphasic Personality Inventory (MMPI-2). Also, an fMRI technique — by presenting distinct homo- and heterosexual sex erotic …

Comprehensive Clinical And Neuroimaging Review Of Posterior Fossa Hemorrhage In Preterm And Term Newborns, Mandy Hsu, Zahra Zhu, Sirajul Islam, Ryan J. Chang, Nouran Hammad, Kalyan C. Bonda, Ermal Aliu, Chintan Gandhi, Gayatra Mainali, Krishnamoorthy Thamburaj, Sunil Naik

Journal of Pediatric Neurology

Posterior fossa hemorrhage (PFH) is a highly morbid condition in preterm and term infants. In this article, we aim to first describe a case of posterior fossa hemorrhage (PFH) and using this example, provide a comprehensive narrative review of the pathophysiology, risk factors, diagnosis, and management of PFH. Management may differ depending on the etiology and based on careful consideration of the risks and benefits of surgical versus conservative management.

Aging In Europe: Implications And Possibilities, Jason L. Powell, Rebecca Steel

Fast Capitalism

No abstract provided.

Setting, Speaking, And Framing In The News Discourse Of Elected Executions: A Play In Three Acts, C. Lee Harrington, Heather Reece, Glenn W. Muschert

Fast Capitalism

No abstract provided.

“No, They’Re Not Digital Natives And They’Re Not Addicted”: An Essay Critiquing Contestable Labels, Nicola F. Johnson

Fast Capitalism

No abstract provided.