Digital Commons Network^™

Debunking The Efficacy Of Standard Contract Boilerplate: Part Iv, David Spratt

Scholarly Articles in Law Reviews & Journals

We have belabored the archaic and prohibited use of "said" as a synonym for "the." But this paragraph needs more work. First, the phrase "irrespective of the fact that" is wordy and could be replaced with the plain language alternative of "even though." Second, "one or more of the parties now is, or may become, a resident of a different state" also could be streamlined. The phrase is easy enough to understand but cut to the chase. Replacing this phrase with "either party now or later resides in a different state" does the trick.

Reflections On Law Student Mental Health By A Dean Of Students After 25 Years, David Jaffe

Scholarly Articles in Law Reviews & Journals

Your faculty need to be educated about how to refer students, how to speak with students who pop into their office. Your Dean, writ-large nationally, Deans need to have the willingness, and again, the bravado, the willingness to go to the faculty and say, "You need to be part of this movement." Whatever that may mean. I would love to see every faculty member taking 30 seconds at the beginning of every class for students to breathe. Thirty seconds of breathing. If you've never done it, do it at home today, deep breaths, and see what it feels like. I …

"It's Okay To Not Be Okay": The 2021 Survey Of Law Student Well-Being, David Jaffe, Katherine M. Bender, Jerome Organ

Scholarly Articles in Law Reviews & Journals

The Survey of Law Student Well-Being, implemented in Spring 2014 [hereinafter "2014 SLSWB"], was the first multi-law school study in over twenty years to assess alcohol and drug use among law students, and it was the first multi-law school study ever to address prescription drug use, mental health, and help-seeking attitudes. The article summarizing the results of the 2014 SLSWB has been downloaded over 12,000 times.

With a desire to learn what has changed since 2014 given the increased emphasis on law student and lawyer well-being among law schools and legal professionals, the authors sought and received grant funding from …

An Experimental Study To Develop An Environmental Friendly Mud Additive Of Drilling Fluid Using Aloe Vera, Monuara Bagum, Jalal M Ahammad, Tahir Husain, M. Enamul Hossain

Faculty Journal Articles

Efficient and optimistic drilling operation depends on a number of parameters and drilling fluid (DF) additives is one of them. Traditional DF mud contains toxic chemical compound that causes environmental issue, cost optimization and reservoir formation damages. Present demands of DF and future challenges have urged researchers to develop eco-friendly drilling fluid additives with minimum impact on the environment. Aloe Vera does not contain any serious toxic compound compared to others DF additives; thus it is used in various cosmetic products. The present investigation leads toward the development of a drilling mud additive using Aloe Vera. The SEM-EDX method is …

A Rodent Animal Model For Forelimb To Lower Jaw Reorganization In Primary Somatosensory Cortex (Si) Barrel Field, Violeta Pellicer Morata

Theses and Dissertations (ETD)

The goal of this study is to examine mechanisms underlying cortical reorganization in rat primary somatosensory (SI) cortex that follows forelimb deafferentation. The majority of human patients suffering from limb loss or brachial plexus avulsion injury, as well as patients that receive brachial plexus anesthesia, report phantom limb sensations/pain which are often associated with cortical reorganization. Patients with upper-limb deafferentation report sensations of the missing hand during tactile stimulation of the face, and this phenomenon has been termed hand-to-face remapping. We sought to develop a rodent model of deafferentation; our model system is the rat SI cortex barrel field present …

Targeting Protein Degradation To Uncover Novel Oncoprotein Drivers Of Acute Leukemia, Fatemeh Keramatnia

Theses and Dissertations (ETD)

Acute Lymphoblastic Leukemia (ALL), the most common childhood cancer and the second most common acute leukemia in adults, arises from clonal expansion of undifferentiated lymphoid precursor cells in bone marrow. Despite the extensive knowledge on its cytogenetic and molecular biology, ALL treatment remains highly challenging especially after relapse. Conventional chemotherapy has shown significant improvement in overall survival rates of pediatric patients up to 90%, however, treatment failure due to ALL relapse occurs in 15-20% of the cases. On the other hand, adults and elderly patients with ALL are considered difficult to treat populations with the 5-year overall survival of 30–40%. …

Immunomodulatory Roles Of The Lysosomal Sialidase Neuraminidase 1, Leigh Ellen Fremuth

Theses and Dissertations (ETD)

Background Sialic acids are key sugar moieties located at the non-reducing terminals of glycan chains on glycoproteins and glycolipids. By virtue of their location, they influence the functions and biochemical properties of the macromolecules they are bound to. Removal of sialic acids in mammalian cells is carried out by four sialidases, which are differentially expressed and localized in distinct subcellular compartments. Neuraminidase 1 (NEU1), the most abundant and ubiquitous of the four sialidases, functions primarily in the acidic environment of the lysosomes, but can hydrolyze substrates at the plasma membrane, at least in certain cell types. The enzyme initiates the …

The Relationship Of Child Health And Parenting Stress To Child Neurocognitive Development, Nancy Alise Farrell

Theses and Dissertations (ETD)

Problem. Although the United States rates high in economic resources, the neurocognitive development (NCD) of children falls behind many other developed nations. Levels of parenting stress may be linked to sociodemographic factors such as the high incidence of poverty in children or health disparities in children, which in turn may affect NCD in children. Using the data from an observational, longitudinal cohort study of a diverse population could provide information related to parenting stress, child health, and related factors to guide and support interventions with families and policies to improve child NCD. Aims. The overall aim of this study was …

Exposure To Per- And Polyfluoroalkyl Substances And Markers Of Liver Injury: A Systematic Review And Meta-Analysis, Elizabeth Costello, Sarah Rock, Nikos Stratakis, Sandrah P Eckel, Douglas I Walker, Damaskini Valvi, Dora Cserbik, Todd Jenkins, Stavra A Xanthakos, Rohit Kohli, Stephanie Sisley, Vasilis Vasiliou, Michele A La Merrill, Hugo Rosen, David V Conti, Rob Mcconnell, Leda Chatzi

Faculty, Staff and Students Publications

BACKGROUND: Experimental evidence indicates that exposure to certain pollutants is associated with liver damage. Per- and polyfluoroalkyl substances (PFAS) are persistent synthetic chemicals widely used in industry and consumer products and bioaccumulate in food webs and human tissues, such as the liver.

OBJECTIVE: The objective of this study was to conduct a systematic review of the literature and meta-analysis evaluating PFAS exposure and evidence of liver injury from rodent and epidemiological studies.

METHODS: PubMed and Embase were searched for all studies from earliest available indexing year through 1 December 2021 using keywords corresponding to PFAS exposure and liver injury. For …

Enhancing Discovery Of Genetic Variants For Posttraumatic Stress Disorder Through Integration Of Quantitative Phenotypes And Trauma Exposure Information, Adam X. Maihofer, Andrew C. Heath, Et Al.

2020-Current year OA Pubs

BACKGROUND: Posttraumatic stress disorder (PTSD) is heritable and a potential consequence of exposure to traumatic stress. Evidence suggests that a quantitative approach to PTSD phenotype measurement and incorporation of lifetime trauma exposure (LTE) information could enhance the discovery power of PTSD genome-wide association studies (GWASs).

METHODS: A GWAS on PTSD symptoms was performed in 51 cohorts followed by a fixed-effects meta-analysis (N = 182,199 European ancestry participants). A GWAS of LTE burden was performed in the UK Biobank cohort (N = 132,988). Genetic correlations were evaluated with linkage disequilibrium score regression. Multivariate analysis was performed using Multi-Trait Analysis of GWAS. …

The Need For A Gender Neutrality Policy In One State's 4-H Program, Nancy Ann Moores

Dissertations

Policies recognizing gender-neutrality and non-binary identities are needed in youth development programs to create a truly inclusive program and a sense of belonging for all youth. This study explored if and how written statewide policies regarding gender- neutrality can most effectively serve members, agents, and volunteers of the 4-H Youth Development Program in the state under study. The context of this study was the 4-H program in one state (agents and administrators as participants) and 4-H programs around the United States (administrators as participants).Preliminary qualitative and quantitative data from my research study indicated that agents in the state under study …

Understanding The Relationship Between Black Chicago Youth And Chicago Drill Music Culture, Dan'iel Tamirra Kendricks

Dissertations

Chicago is most noted as a beautiful, Midwestern city, set to the backdrop of Lake Michigan, with skyscrapers and the bustling energy of the downtown Magnificent Mile. The “Tale of Two Cities,” Chicago is a city full of hope, opportunity, and potential for some, but a city plagued with poverty, violence, disinvestment, and hopelessness for others. There has been a significant increase in the awareness of the violence happening across Chicago. The emergence of social media has provided a direct and unfiltered view of the reality of violence the city has faced on an ongoing basis. Crimes such as shootings, …

Origin Of "Shyster" Revisited: Issue Of The Identity Of Cornelius W. Terhune, Gerald Leonard Cohen

Arts, Languages and Philosophy Faculty Research & Creative Works

No abstract provided.

"Insanity Is Smashing Up Against My Soul": The Fifth Circuit And Competency To Be Executed Cases After Panetti V. Quarterman, Michael L. Perlin, Talia Roitberg Harmon

Articles & Chapters

One of the open secrets of death penalty law and policy is the astonishingly high percentage of individuals on death row with serious mental disabilities. This is well known to lawyers who represent this cohort (and presumably, equally well known to the district attorneys who nevertheless prosecute them and the judges who try and sentence them), but is not generally discussed in the press nor, certainly, in political discourse. In the aggregate, this is far beneath society’s radar.

It is now over 14 years since the US Supreme Court decided a case that clarified the underlying issues. In Panetti v. …

The Exclusion Of Public Legal Education From Mandatory And Aspirational State Pro Bono Service Requirements, Amy Wallace

Articles & Chapters

Pro bono service is embedded in legal education and practice. Every year, lawyers and law students across the United States engage in countless hours of pro bono service. There are over 1.3 million lawyers in the country and more than one hundred thousand law students enrolled in law school. Lawyers perform an average of thirty-seven hours of pro bono work each year. They reference several factors that motivate them to perform this work but the desire to help people in need ranks highest. Professional duty is also listed as an important factor for lawyers choosing to perform pro bono work. …

A Judicially Manageable Test To Restore Accountability, David Schoenbrod

Articles & Chapters

No abstract provided.

Prosecutorial Nonenforcement And Residual Criminalization, Justin Murray

Articles & Chapters

In recent years a small but influential group of locally elected prosecutors committed to criminal justice reform have openly refused to enforce various criminal laws—laws prohibiting marijuana possession, sentence enhancements, laws authorizing the death penalty, and much more—because they see those laws as unjust and incompatible with core reform objectives. Condemned by many on the political right for allegedly usurping the legislature’s lawmaking role and praised by many on the left for bypassing dysfunctional state legislatures in favor of local solutions, these prosecutorial nonenforcement policies are commonly said to have the same effect as nullifying, or even repealing, the laws …

Microplastics In The Atmosphere Of Ahvaz City, Iran, Sajjad Abbasi, Neamatollah Jaafarzadeh, Amir Zahedi, Maryam Ravanbakhsh, Somayeh Abbaszadeh, Andrew Turner

School of Geography, Earth and Environmental Sciences

Airborne particulate matter (PM) with an aerodynamic size cutoff of 10 µm (PM10) has been collected using a high volume air sampler at two locations (urban and residential) in the city of Ahvaz, Iran, for sixteen 24-hour periods over four months (late summer to early winter). Microplastics (MPs) in the PM were isolated after sample digestion and were subsequently characterised by established techniques. All MPs sampled (n = 322) were of a fibrous nature, with polyethylene terephthalate, nylon and polypropylene being the dominant polymers and consistent with textiles and fabrics as the principal source. Despite a distinct seasonality (temperature and …

Infection With The Hepatitis C Virus Causes Viral Genotype-Specific Differences In Cholesterol Metabolism And Hepatic Steatosis, David A. Sheridan, Isaac Thom Shawa, E. Louise Thomas, Daniel J. Felmlee, Simon H. Bridge, Dermot Neely, Jeremy F. Cobbold, Elaine Holmes, Margaret F. Bassendine, Simon D. Taylor-Robinson

Peninsula Medical School

Lipids play essential roles in the hepatitis C virus (HCV) life cycle and patients with chronic HCV infection display disordered lipid metabolism which resolves following successful anti-viral therapy. It has been proposed that HCV genotype 3 (HCV-G3) infection is an independent risk factor for hepatocellular carcinoma and evidence suggests lipogenic proteins are involved in hepatocarcinogenesis. We aimed to characterise variation in host lipid metabolism between participants chronically infected with HCV genotype 1 (HCV-G1) and HCV-G3 to identify likely genotype-specific differences in lipid metabolism. We combined several lipidomic approaches: analysis was performed between participants infected with HCV-G1 and HCV-G3, both in …

‘It’S Not Just Music, It Helps You From Inside’: Mixing Methods To Understand The Impact Of Music On Young People In Contact With The Criminal Justice System, L Caulfield, A Jolly, E Simpson, Y Devi-Mcgleish

School of Health Professions

In response to some of the criticisms of previous research into the arts in criminal justice, this article presents findings from research with a music programme run by a Youth Offending team (YOT). Data were collected on the attendance of 42 participants at YOT appointments – matched against a comparison group – and measures of change over time in musical development, attitudes and behaviour and well-being. Participants who completed the music programme were statistically more likely to attend YOT appointments than a comparison group. There were statistically significant improvements in participants’ self-reported well-being and musical ability over the course of …

Visual Perspective Taking Without Visual Perspective Taking, S Samuel

School of Psychology

What happens when an observer takes an agent's visual perspective of a scene? We conducted a series of experiments designed to measure what proportion of adults take a stimulus-centered rather than agent-centered approach to a visual perspective taking task. Adults were presented with images of an agent looking at a number (69). From the perspective of the viewer, the number appeared upside down. We then asked participants what number the agent saw. An agent-centered approach, that is, one that takes into account the other's visual experience, should produce the correct answer "69". Even an egocentric error (i.e., the participant's own …

The Father Of Faith Rationally Reconstructed, Levi Durham

Faith and Philosophy: Journal of the Society of Christian Philosophers

No abstract provided.

Sucroferric Oxyhydroxide For Hyperphosphatemia: A Review Of Real-World Evidence, Daniel W Coyne, Stuart M Sprague, Marc Vervloet, Rosa Ramos, Kamyar Kalantar-Zadeh

2020-Current year OA Pubs

Hyperphosphatemia is a common complication in dialysis-dependent patients with chronic kidney disease. Most dialysis-dependent patients need oral phosphate binder therapy to control serum phosphorus concentrations. Most phosphate binders have a high daily pill burden, which may reduce treatment adherence and impair phosphorus control. Sucroferric oxyhydroxide is a potent iron-based phosphate binder approved for use in dialysis-dependent patients in 2013. A randomized controlled trial of sucroferric oxyhydroxide demonstrated its efficacy for reduction of serum phosphorus with a lower pill burden than sevelamer carbonate. Clinical trials carefully select patients, monitor adherence, and routinely titrate medications to a protocol-defined goal. Consequently, trials may …

Association Between Self-Reported Body Mass Index And Active Life Expectancy In A Large Community-Dwelling Sample Of Older U.S. Adults, Haomiao Jia, Erica I. Lubetkin

Publications and Research

Background: Obesity may have a protective effect (greater survival) in older adults, a finding known as the "obesity paradox." This study examined the association between self-reported body mass index (BMI) and active life expectancy (ALE) among older U.S. adults.

Methods: Using the Medicare Health Outcomes Survey Cohort 15 (2012 baseline, 2014 follow-up), we estimated life expectancy and ALE by participants' baseline BMI and age using multi-state models. A participant was classified as in an active state if this person reported having no difficulty for any of these six activities of daily living (ADLs).

Results: Small differences in life expectancy were …

Gen-Z, Gender, & Governmental Grievances: A Post-Transition Political Philosophy For The Newest Generation Of Women In A ‘Failed’ State., Olivia Harvey

Independent Study Project (ISP) Collection

Over a decade since the Jasmine Revolution in Tunisia, a new generation has come into adulthood, grappling with anxieties about their future in the midst of continuous national instability. This paper aims to bridge their sentiments of disillusionment and disengagement towards politics together with general conceptions of life by ‘Generation-Z’ women (between the ages of 18 and 30). The findings follow conceptions of history, freedoms, rights and personal life, particularly as they are affected by gender in Tunisian society. Specifically, this study is interested in how these aspects have changed from before to after the political changes of the past …

“Somos Un Pueblo Fumigado”: Un Análisis De La Lucha Contra La Fumigación Y Sistema De Agronegocios En La Provincia De Buenos Aires, Samuel Brooks

Independent Study Project (ISP) Collection

Esta investigación estudia el movimiento contra el sistema de monocultivo de soja transgénica, la fumigación con “agrotóxicos,” y los grandes agronegocios en la provincia de Buenos Aires. Con la información de tres entrevistas y una visita a un encuentro de habitantes de pueblos fumigados, examino los diferentes “marcos” que el movimiento tiene para describir las formas en que ellos expresan el problema actual, las soluciones que proponen, sus métodos para motivar a la gente, y la perspectiva del movimiento en general. También, incorporo perspectivas académicas para profundizar el análisis de las diferentes áreas de discurso en el movimiento y definir …

Duelos Incompletos: La Situación Actual Del Acceso A Servicios De Salud Mental Para Los Sobrevivientes Del Conflicto Armado En Ayacucho, Olivia Frison De Angelis

Independent Study Project (ISP) Collection

La salud mental es un asunto relativamente nuevo en el Perú. En la ciudad andina de Ayacucho en la provincia de Huamanga, el gobierno solamente empezó a financiar proyectos de salud mental accesibles a las comunidades campesinas en los últimos seis años, desde 2016. Considerando que la región de Ayacucho ha sufrido el número más alto de muertes y desaparecidos durante el conflicto armado interno de 1980 hasta 2000, es atroz que estas medidas han empezado tan tarde. Entretanto, mientras que las conversaciones avanzan sobre cómo seguir haciendo reparaciones de salud mental a los sobrevivientes del conflicto, ellos siguen con …

La Política Cultural Del Aborto: Las Percepciones Y El Manejo Del Aborto En Arica, Chile, Eva Strelitz-Block

Independent Study Project (ISP) Collection

Chile has a long history of restricting access to legal abortion. Until 2017, when the government passed the law N° 21.030 decriminalizing abortion on three grounds, abortion was completely illegal. However, despite this movement towards decriminalization, legal abortion access is still very limited and highly restricted. In this criminalized, highly stigmatized environment, self-managed abortion has emerged as a way to transform the landscape of abortion. This qualitative, exploratory study seeks to explore perceptions of abortion and practices of abortion management both within and outside of the official healthcare system among women and people with the capacity to become pregnant and …

Conservation And Variation In Agricultural Landscapes: A Survey Of Insect Populations Across Naranjilla Cultivation Methods In The Eastern Andean Cloud Forest, Ian Zakelj

Independent Study Project (ISP) Collection

This study compared insect biodiversity among five sites in agricultural landscapes and natural forest in the El Placer community in the valley of the Rio Pastaza in the eastern Andean cloud forest. The area is of vital importance to conservation, as it falls in the ecological corridor between the Sangay and Llanganates national parks. The primary crop produced by the residents of El Placer is naranjilla, and it is cultivated in a variety of manners, mostly with intensive chemical use. The goal of the study was to find out which types of practices were the least harmful to the insect …

Water: The Gift And The Curse: A Climate Change Preparedness Study On An Increased Rainfall Scenarios In The Yunguilla Cloud Forest, Ecuador, Emilia Dick Fiora Del Fabro

Independent Study Project (ISP) Collection

The purpose of this project was to try and better understand the risks posed to the Yunguilla community in an increased rainfall climate change scenario. While climate modeling is not exact, many models do predict increased rain and storm intensity in this area (“Explainer…”, 2018). This project studies erosion risk, and the potential damage to crops through a series of experiments and mapping.

The first experiment used three hydration percentages 50, 75 and 100, to water two crop types, Fragaria and Caspium, and monitored plant health to see the water's effect. The hydraulic stress testing did not model an increased …