Digital Commons Network^™

Frequency Of Genetic Variants At The Mc1r Locus In A Student Population, Emmalea K. Dowdy, Grace C. Stubblefield, David K. Peyton

2022 Celebration of Student Scholarship - Poster Presentations

The Melanocortin-1 Receptor gene (MC1R) encodes a protein that is associated with pigmentation in vertebrate animals. An extraordinary number of variations in this gene have arisen over time due to the importance of pigmentation in camouflage, photosensitivity, vitamin D production, and other evolutionary factors. Variations in the MC1R gene sequence became important to survival as humans migrated out of Africa and into cooler climates with less sun exposure, where lighter skin pigmentation (and therefore more vitamin D production) was key to survival. These genetic variations (alleles) continue to exist in modern humans. Recent research into the MC1R gene variations shows …

Research, Testing, And Validation Of Small Satellite Designs: Cubesats, Cansats, Pocketqubes, And Femtosatellites, Jason A. Combs, Jose L. Garcia

2022 Celebration of Student Scholarship - Poster Presentations

The focus of this project, through research and testing, was to prepare various elements of small satellite experiential education curriculum. Rather than be constrained to the expensive and long-term timelines of a larger satellites, students can assemble, test, and operate various classes of small satellites in a valuable learning experience that will prepare them to work on larger projects. The true benefit of a PocketQube, CanSat, or femtosatellite is that they can be built with less money, less experience, and less long-term commitment while providing a scaled version of the real-life satellite development process that will engage and inspire students. …

Novel Gain-Of-Function Mutations In The Telomerase Rna Of Saccharomyces Cerevisiae, Keenan Conley, Madison Frazier, Melissa Mefford

2022 Celebration of Student Scholarship - Poster Presentations

Yeast are eukaryotic organisms that contain liner chromosomes. At the ends of these chromosomes, there are special regions known as telomeres. Telomeres are composed of non-coding nucleotides that serve to protect the vital coding DNA found throughout the rest of the chromosome. During the process of DNA replication, however, telomeres become progressively shorter which can lead to cellular senescence. To solve this issue, yeast express the enzyme telomerase. Telomerase is composed of a telomerase reverse transcriptase protein (TERT) and telomerase RNA (TLC1) in yeast. When telomeres become too short, telomerase extends telomeres by adding to the 3’ overhang. Telomeres shorten …

Technology In Workplace Communication By Generation, Hannah Meadows, Christy Trent

2022 Celebration of Student Scholarship - Poster Presentations

The purpose of this research study was to determine the generational differences in the use of communication technology in the workplace. Most employees feel a deeper sense of connection to those in their own generational group. This survey looks at ideologies across four generations, Baby Boomers, Generation X, Millennials, and Generation Z, to help give employers some insight into why employees feel this way and encourage better communication in the workforce.

Fungi In A Warmer World: Fungal Diversity In The Tropical Miocene Climate Optimum Of The Clarkia Region Of Idaho, Usa, J. Fairchild, L. Lennex-Stone, T. Horsfall, L. Tarlton, S. Jones, A. Caldwell, O. Vanderespt, L. Smallwood, A. Patel, J. O'Keefe, I. Romero, N. Nunnez Otano, M. Pound

2022 Celebration of Student Scholarship - Poster Presentations

A knowledge gap associated with how fungal communities change in response to climate was identified in the 2018 State of the World Fungi report (Willis, 2018). While it is virtually impossible to test in the present, fungal assemblage changes can be studied in sediments from a warmer-than-present period such as the Miocene Climate Optimum (MCO) (Romero et al. 2021; O’Keefe 2017). The Fungi in a Warmer World project aims to generate and analyze a global-scale data set of fungal biodiversity, ecology, and associated flora from MCO sediments. This dataset will be used to model past fungal assemblage changes across the …

Morphometrics Of The Rare Earwigfly Merope Tuber, Nicholas Finch, Sean O'Keefe

2022 Celebration of Student Scholarship - Poster Presentations

Merope tuber Newman (Mecoptera: Meropeidae) is a rare North American species of earwigfly, which is closely related to common scorpionflies. “Earwigfly” refers to three different species: the Western Australian Austromerope poulton, the South American Austromerope brasiliensis, and finally, the Eastern North American Merope tuber. This last species was the focus of our study. Johnson’s 1995 study was based on 160 earwigflies, where he measured the female abdomen length, male and female forewing length, and male basistylus and dististylus length. In their 2014 study, based on 82 earwigflies, Skvarla, Hartshorn, and Dowling measured head width, pronotum width, forewing length, abdomen length, …

Encouraging Increased Ppe Compliance: A Quality Improvement Project, Christen Ballard, Hannah Carpenter, Skyler Harper, Angela Marcum, Suzi White

2022 Celebration of Student Scholarship - Poster Presentations

Personal protective equipment (PPE) is used to minimize infection transmission from patient to healthcare worker, or vice versa. During a clinical rotation in a large urban teaching hospital, it was noted that a number of nurses failed to adhere to proper PPE policies. A literature review focusing on thirty-two studies found that average nurse compliance to proper PPE is 34%. This review included an overall discussion of factors affecting compliance, as well as a more in-depth review of the effect of education on PPE compliance, how comfort and proper fitting affects compliance, and the general effectiveness of PPE when used …

“The Never Ending Story:” Circularizing Ch. Viii In Saccharomyces Cerevisiae, Chisom Iloegbunam, Melissa Mefford

2022 Celebration of Student Scholarship - Poster Presentations

Chromosomes are molecules of DNA that hold large quantities of genetic material in an organism. Generally, in nature, eukaryotic chromosomes are linear while prokaryotic chromosomes are circular. Since they are linear, eukaryotic chromosomes possess telomeres, or repetitive nucleotide sequences, on their ends. This significant difference in structure requires different additions to the basic replication process. In prokaryotes, replication starts at a single point on the chromosome and continues until the whole chromosome has been copied. In eukaryotes, replication happens in fragments with multiple starting points. Because of this more complicated replication process, the free 3’ ends of our DNA cannot …

College Students’ Knowledge And Use Of Herbal Supplements: Informed Decision, Health Risk, Or Marketing Ploy?, Jillian Wallshield, Wilson Gonzalez-Espada

2022 Celebration of Student Scholarship - Poster Presentations

The purpose of this study is to better understand the extent to which college students from Eastern Kentucky use Herbal Supplements (HS). The research questions for this study were:

• How do the participants find out about HS?

• How helpful do participants perceive the HS they take to be?

• What misconceptions do participants have regarding HS?

• Does a positive or negative attitude towards science change the usage rate of HS?

A New Colorimetric Assay Of Apurinic/Apyrimidinic (Abasic) Sites Of Deoxyribonucleic Acid (Dna) Using Bicinchoninic Acid [, Isaiah O. Stephens, Elizabeth M. Thomas

2022 Celebration of Student Scholarship - Poster Presentations

Apurinic/apyrimidinic (AP or abasic) sites are DNA lesions that result from the loss of a nucleobase by hydrolysis of the N-glycosyl bond. It is estimated that AP sites are the most frequent lesions in cells with about 10,000-50,000 times per day per cell under typical aerobic conditions [2]. The formation of AP sites is caused by environmental and cancer therapeutic genotoxins such as alkylating agents, oxidizing agents, ionizing radiation, and ultraviolet radiation.

Drone Mapping On Eagle Lake Dam, Nathan Sparks, Timothy Hare

2022 Celebration of Student Scholarship - Poster Presentations

The Eagle Lake Dam is an iconic part of Morehead State’s campus. It can be seen from much of campus and serves as one of the best views around. It is also the single most important structure on campus. A significant percentage of the campus would be damaged or impaired, as well as many people would be endangered if the dam failed. Hence, I am starting a multi-person and multi-year initiative to monitor Eagle Lake Dam using UAV and remote sensing technology. I hope to have teams make annual 3D models of Eagle Lake Dam over the next several years …

Beetle Diversity Within Ecosystems; Insight Of The Order Coleoptera In The Eastern Kentucky Region, Blake Branham, Hannah Pyles, Charles Lydeard, Sean O'Keefe

2022 Celebration of Student Scholarship - Poster Presentations

Having a multitude of definitions, biodiversity can most commonly be seen as the variety and diversity of life within an ecosystem. Its relevance is crucial for species survival and resource availability; a lack of biodiversity sets an ecosystem up for failure, reducing its productivity, species richness, and increasing organismal vulnerability. Measuring biodiversity is crucial for the understanding of an ecosystem’s health, giving scientists knowledge of its stability, productivity, and persistence. This collected information can be implemented in various ways outside the scientific field as well, such as with policy decisions and legal regulations. Biodiversity is most commonly analyzed through quantitative …

Classroom Management In Kentucky, Sarah Miller, Kim Nettleton

2022 Celebration of Student Scholarship - Poster Presentations

Classroom management is a skill many incoming teachers struggle to balance while teaching. Good classroom management aids in establishing a learning environment that encourages both social and academic learning. The case studies recorded examine the classroom management methods of a select group of educators. These subjects described their methods of classroom management, whether self-made or research-based, through a series of interview questions. The interview questions establish an understanding of current practice of classroom management regarding rules, procedures, positive relationships, and classroom arrangement. In evaluating different variations of classroom management, the effectiveness, and advantages and disadvantages of different classroom management methods …

Love And Education In Plato's Symposium, Brooke Boggs, Timothy L. Simpson

2022 Celebration of Student Scholarship - Poster Presentations

This paper seeks to illuminate the significance of Socrates' entrance into a series of speeches by exploring the connection between love and learning in Plato's Symposium. We begin by presenting historical and social contexts relevant to the dialogue and its author. We then turn to the dialogue, outlining the fundamental components of each speech and, moreover, analyzing each speech with the aim of eliciting educational implications which are later highlighted and expanded on by Socrates. We examine these pedagogical connotations through a thorough investigation of each speech, keeping a keen eye on Socrates. We approach our examination of Socrates’ speech …

Telehealth As A Preventative And Quality Control Measure For Hospital Readmissions And Comprehensive Health Factors: A Quality Improvement Project, Miracle Thacker, Randa Thompson, Madison Whitenack, Elizabeth Williams, Kaitlyn Workman, Suzi White

2022 Celebration of Student Scholarship - Poster Presentations

Exploring Telehealth as a tool for reducing hospital readmission rates and improving client long-term health. Findings are to be shared with staff nurses to improve client outcomes.

A Meta-Analysis Of Quantitative Collecting Techniques For Spiders, Eliana Eldridge, Joshua Hicks, Sean O'Keefe

2022 Celebration of Student Scholarship - Poster Presentations

Quantitative sampling of organisms is often used to provide information in ecological studies, monitor populations, and aid in biodiversity projects. Many studies involve the quantitative sampling of spiders. In this meta-analysis study, 207 peer-reviewed journal articles formed the basis of an initial data set for a quantitative analysis of spider collection techniques. Data collected included country of study, mode of study, trapping techniques used, spider diversity, and number of specimens collected. Our meta-analysis gathered research articles that included 33 different countries of study. Trapping techniques greatly vary depending on the habitat in which spiders dwell. These were divided into aerial, …

A Preliminary Survey On The Biodiversity Of Wasps In Eastern Kentucky, Lorien Molstad, Zoe Baker, Julia Fitzpatrick, Bethany Lucio, Sean O'Keefe

2022 Celebration of Student Scholarship - Poster Presentations

Biodiversity is the measure of variability of interactions between living organisms within an area. Biodiversity contributes significantly to the production of different life sustaining resources and supports a diversity of ecological life. A greater biodiverse area can help maintain environmental balance and maintain ecological diversity and health. There are multiple economic, cultural, and scientific reasons as to why biodiversity is important. When assessing biodiversity, mammals and birds are commonly used as surrogates. The problem with mammals and birds is that there are relatively few species and relatively few individuals in an area, so quantitative assessment can be difficult. However, insects …

Photography Practicum: Learning The Basics Of Managing A Fine Art Photography Darkroom, Brooklin Routt, Allison Jones, Frazier Pack, Robyn Moore

2022 Celebration of Student Scholarship - Poster Presentations

The photography practicum provides Art and Design student researchers with the practical experience of managing a fine art photography studio. Students learn how to operate, manage, and maintain industry-standard fine art archival inkjet printers as well as a fourteen-station traditional black and white darkroom. This project provides essential expertise and knowledge that students, as lab monitors, both share with other students and incorporate into their own fine art practice and professional activities. Student researchers learn how to mix, store, and dispose of photographic chemistry, provide daily assistance to undergraduate and graduate photography students, and generate ideas for improvements to the …

Survey Of Spiders Within Eastern Kentucky, Mercy Hailu, Bailey Bullock, Joshua Hicks, Eliana Eldridge, Sean O'Keefe

2022 Celebration of Student Scholarship - Poster Presentations

Biodiversity is known to be the variation of living organisms compromising several levels, beginning from genes, then species, communities, then finally ecosystems. Biodiversity is crucial in maintaining ecological balance, boosting ecosystem productivity, and determining the quality of ecosystem services such as pest management in agriculture. Being aware of biodiversity's importance can also help with the prevention of continuous threats to biodiversity and be best prepared to manage conservation challenges. Typically, mammals, birds, and plants are used to assess biodiversity. However, spiders may be effective in indicating environmental change because they are taxonomically quite diverse, species fill a variety of ecological …

Creating The First Genetically Engineered Eukaryote With Circular Chromosomes, Duncan Mcginnis, Melissa Mefford

2022 Celebration of Student Scholarship - Poster Presentations

Prokaryotes and eukaryotes differ in their chromosome structure; prokaryotes have a single circular chromosome, while eukaryotes have multiple circular chromosomes. Linear chromosomes are more complex than circular ones and create problems for eukaryotes. Many of these issues are solved by telomeres—long, repetitive sequences of DNA found on the ends of most eukaryotic chromosomes. They protect the ends from harm and limit how many times a cell can divide. Two of our greatest medical challenges, cancer and aging, are closely related to telomeres; most cancers upregulate telomerase, and aging human cells display shorter telomeres. To investigate the evolution and function of …

Fungi In A Warmer World: Middle Miocene Fungal Assemblages And Diversity From Alum Bluff, Florida, Savannah Jones, Taylor Horsfall, Laikin Tarlton, Abigayle Caldwell, Liberty Smallwood, Jolene Fairchild, Libby Lennex-Stone, Alyssa Patel, Olivia Vanderespt, Ingrid Romero, Jennifer O'Keefe, Noelia Nunez Otano, Sophie Warny, Matthew Pound

2022 Celebration of Student Scholarship - Poster Presentations

Fungi play a key role in the terrestrial carbon cycle, soil formation, and overall plant growth as terrestrial decomposers (1, 2). Thus, the study of fungi, especially in the fossil record, is critical to understanding how fungal assemblages will react to future warming events. Fossil fungi provide a large-scale, long-term dataset unavailable from modern records, allowing for the generation of viable paleoclimate reconstructions and predictions (3, 4). Despite their importance and advantages in forming ecological and climatological interpretations, deep-time fungi have been underutilized (3). The Fungi in a Warmer World (FiaWW) project aims to deliver the first global view of …

Risky Behaviors In Central Appalachia/Eastern Kentucky: Teen Pregnancy And Sexually Transmitted Infections, Allison Hyden, Lisa Shannon

2022 Celebration of Student Scholarship - Poster Presentations

According to the Robert Wood Johnson Foundation (2017), Central Appalachia had a teen birth rate 63% higher than the national rate. In the Big Sandy Region of Kentucky, the teen pregnancy rates per 1,000 females ages 15-19 were Floyd at 55.9, Johnson at 30.3, Magoffin at 57.3, Martin at 50.7, and Pike at 38.2. These were more than double the national rate (16.9) (Centers for Disease Control, 2021). Sexually transmitted infection (STI) rates within the area were also high. Chlamydia increased 200%, and syphilis increased 300% between 2011 and 2017; many of these cases were in young adults (Meehan, 2018). …

The Craft Academy Robotics Project, Daniel Brooks, Josh Day, Brianna Kayatin, Logan Lee, Shawn Nelson, Brady Sammons, Paul Zigo, Rachel Rodgers

2022 Celebration of Student Scholarship - Poster Presentations

To begin, the team’s research project consisted of a robot that could compete on a 12-foot by 12-foot playing field alongside 3 other robots. The robot had to fit within an 18in-by-18in limit, it could be made of a variety of materials and motors specified in the game manual to help it achieve the most amount of points possible. There are many ways to earn points in Freight Frenzy divided into 3 sections, Autonomous, Tele-Operation or “Op” for short, and End-Game: In the Autonomous section, the match starts with a 30-second Autonomous Period where Robots are operated only via pre-programmed …

Fungi In A Warmer World - Fungal Diversity From The Peak Warming Of The Miocene Climate Optimum As Recorded In The Latah Formation, Clarkia, Idaho, Usa, J. Fairchild, I. C. Romero, N. B. Nunez Otano, S. Warny, M. J. Pound, J. M. K. O'Keefe

2022 Celebration of Student Scholarship - Poster Presentations

Microfungi are a vital part of ecosystems as they help with key processes, such as carbon and nutrient cycling, especially through the actions of mycorrhizal and saprotrophic members (Nuñez Otaño et al., 2015, 2021; Willis et al., 2018). Microfungi can also be good indicators of plant biodiversity in an area because many fungal taxa are host-specific (Rutten et al., 2021; Francioli et al., 2021; Hu et al., 2021; Wijayawardene et al., 2022 ). Despite being crucial components in ecosystems, they are often overlooked. In the fossil record, microfungi have a high preserva􀆟on rate and they are often preserved close to …

"Familles, Je Vous Hais!": The Family In The French Interwar Novel, Chandler Abshire

Yale Graduate School of Arts and Sciences Dissertations

Under the Third Republic, social and political theorists responded to national crises by advocating for a strengthening of the traditional patriarchal family. After the French defeat in the Franco-Prussian war of 1870-1, officials put faith in the family as a panacea for the various demographic and moral ills that led to the defeat. The interwar period again saw the return of such calls, but authors of the interwar period carry out clear critiques of the patriarchal family as a source not of moral and reproductive strength, but rather of prejudice and stagnation. The interwar period is often overlooked by scholars …

Human Engineered Pulsatile Conduits Using Engineered Heart Tissue Of Defined Composition And Fiber Orientation, Christopher William Anderson

Yale Graduate School of Arts and Sciences Dissertations

Tissue engineering and regenerative medicine are relatively new fields that aim to combine principals of chemistry, physics and biology to recreate tissues of the body within lab settings. By utilizing these concepts, novel tissues can be created from entirely biologic material for use as therapeutic replacement tissues. The advent of stem cell technology has been an incredible enabling factor for tissue engineering as a field, especially that of human induced pluripotent stem cells (hiPSCs). hiPSCs are a class of stem cell that may be readily produced using non-invasively derived patient samples that are subsequently transfected with what are commonly known …

Essays On Marginal Treatment Effects, Vitor Augusto Possebom

Yale Graduate School of Arts and Sciences Dissertations

In this dissertation, I discuss identification problems with two sources of endogeneity. In both chapters, one source of endogeneity is self-selection into treatment. To address this problem, I use the Marginal Treatment Effect framework developed by Heckman and Vytlacil (2009). In the first chapter, I partially identify the marginal treatment effect (MTE) function when the treatment variable is misclassified. To do so, I explore three sets of restrictions on the relationship between the instrument, the misclassified treatment and the correctly measured treatment, allowing for dependence between the instrument and the misclassification decision. If the signs of the derivatives of the …

Essays On Development Microeconomics In Ghana, Nathan Earl Barker

Yale Graduate School of Arts and Sciences Dissertations

Developing countries are urbanizing, transitioning out of agriculture, and expanding social protection programs. In order to understand the economic consequences of these phenomena, it is important to understand the way that individual and household behavior adjusts in response to these changes. This dissertation examines this interplay; I study how cultural institutions and structural transformation interact, and evaluate the effects of a specific form of social protection: cognitive behavioral therapy. In Chapter 1, I examine the ways in which a specific set of cultural institutions, land inheritance rules, interact with economic opportunities outside of agriculture. In particular, I examine the effects …

The Impacts Of Team-Based Care On Primary Care Quality: Evaluating Evidence From The State Innovation Model (Sim) Program In Connecticut, Emily Boudreau

Yale Graduate School of Arts and Sciences Dissertations

In 2013, CMMI awarded Connecticut a $45 million State Innovation Model (SIM) grant to support healthcare payment and delivery model reforms aimed at improving health system performance, increasing quality of care, and decreasing costs. In the five years that followed, the Office of Healthcare Strategy led care delivery changes across the state with an emphasis on bolstering the role of primary care. In particular, many of these efforts centered on furthering team-based, patient-centered models, such as the patient-centered medical home (PCMH). In this dissertation, I use physician, patient, clinical outcome, and organizational data from the SIM project to explore the …

Functional Profiling Of Human Commensal Metabolites In Colorectal Cancer And Pain Sensation, Yiyun Cao

Yale Graduate School of Arts and Sciences Dissertations

The gastrointestinal tract contains the largest number and greatest diversity of microbes which are referred to collectively as the gut microbiota. Alterations in microbiota dysbiosis are associated with diverse disease states, including colorectal cancer (CRC), inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). However, the causative mechanisms mediated by the gut microbiota are still to be illustrated. Particularly, the gut commensals encode ~150 times more genes than the human genome and thousands of metabolites that mostly lack functional annotations or structural identification. Therefore, the functional profiling of human commensal metabolites is promising to reveal the molecular mechanisms of the …