Digital Commons Network^™

Whose Body Is Deserving: Discourse, Power, And Ideologies Concerning Non-Normative Bodies On Instagram, Misty Thomas

English Language and Literature ETDs

This dissertation uses FCDA to investigate the construction and control of the boundaries of normativity as they relate to the body. Data in the form of comments was collected from three different Instagram accounts run by individuals with non-normative bodies. From the data, I argue that not only are non-normative bodies controlled through the coded language of health, but through racialized dehumanization. Even alleged demonstrations of support are problematized through what is being supported. The Instagram comments left on the accounts of non-normative bodies demonstrates that these bodies are suppressed as a way to maintain normative ideologies.

Intake Patterns Of Specific Alcoholic Beverages By Prostate Cancer Status, Hui Yi Lin, Tung-Sung Tseng, Xinnan Wang, Zhide Fang, Arnold H. Zea, Liang Wang, Julio Pow-Sang, Catherine M. Tangen, Phyllis J. Goodman, Alicja Wolk, Niclas Håkansson, Manolis Kogevinas, Javier Llorca, Hermann Brenner, Ben Schöttker, Jose Esteban Castelao, Manuela Gago-Dominguez, Marija Gamulin, Davor Lessel, Frank Claessens, Steven Joniau, Jong Y. Park

School of Public Health Faculty Publications

Background: Previous studies have shown that different alcoholic beverage types impact prostate cancer (PCa) clinical outcomes differently. However, intake patterns of specific alcoholic beverages for PCa status are understudied. The study’s objective is to evaluate intake patterns of total alcohol and the three types of beverage (beer, wine, and spirits) by the PCa risk and aggressiveness status. Method: This is a cross-sectional study using 10,029 men (4676 non-PCa men and 5353 PCa patients) with European ancestry from the PCa consortium. Associations between PCa status and alcohol intake patterns (infrequent, light/moderate, and heavy) were tested using multinomial logistic regressions. Results: Intake …

Convection Enhanced Delivery Of The Oncolytic Adenovirus Delta24-Rgd In Patients With Recurrent Gbm: A Phase I Clinical Trial Including Correlative Studies, Erik H P Van Putten, Anne Kleijn, Victor W Van Beusechem, David Noske, Cor H J Lamers, Anna L De Goede, Sander Idema, Daphna Hoefnagel, Jenneke J Kloezeman, Juan Fueyo, Frederick F Lang, Charlotte E Teunissen, René M Vernhout, Cathy Bakker, Winald Gerritsen, David T Curiel, Arnold Vulto, Martine L M Lamfers, Clemens M F Dirven

Faculty, Staff and Student Publications

Purpose: Testing safety of Delta24-RGD (DNX-2401), an oncolytic adenovirus, locally delivered by convection enhanced delivery (CED) in tumor and surrounding brain of patients with recurrent glioblastoma.

Patients and methods: Dose-escalation phase I study with 3+3 cohorts, dosing 107 to 1 × 1011 viral particles (vp) in 20 patients. Besides clinical parameters, adverse events, and radiologic findings, blood, cerebrospinal fluid (CSF), brain interstitial fluid, and excreta were sampled over time and analyzed for presence of immune response, viral replication, distribution, and shedding.

Results: Of 20 enrolled patients, 19 received the oncolytic adenovirus Delta24-RGD, which was found to be safe and feasible. …

Hereditary Alpha-Tryptasemia Modifies Clinical Phenotypes Among Individuals With Congenital Hypermobility Disorders, Maribel Vazquez, Jack Chovanec, Jiwon Kim, Thomas Dimaggio, Joshua D Milner, Clair A Francomano, Christina A Gurnett, Marco Ritelli, Marina Colombi, Jonathan J Lyons

Open Access Publications

Hereditary alpha-tryptasemia (HαT) is an autosomal dominant (AD) genetic trait characterized by elevated basal serum tryptase ≥8 ng/mL, caused by increased α-tryptase-encoding

Exploring The Relationship Between Attention-Deficit/Hyperactivity Disorder And Creativity, Anna Shea Hall, Anna Shea Hall

Honors College Theses

Attention-Deficit/Hyperactivity Disorder (ADHD) is an important topic to study because of its prevalence, impact, and a multitude of unknown interactions of the disorder with creativity. Creativity is a cognitive process defined by lessened cognitive control and lower inhibitions in the prefrontal cortex (Chrysikou, 2018), which are characteristics of ADHD (APA, 2017; Brunkhorst-Kanaan et al., 2021; Kirov & Brand, 2014; Laugesen et al., 2017; Moen et al., 2014; Staikova et al., 2013) This study explored how ADHD is connected with three sub-variables of creativity: divergent thinking, uniqueness of generated ideas, and flow of ideas. Connections were explored via a survey of …

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.

Cytospin-A Regulates Colorectal Cancer Cell Division And Migration By Modulating Stability Of Microtubules And Actin Filaments, Fan Fan, Jason Roszik, Ling Xia, Susmita Ghosh, Rui Wang, Xiangcang Ye, David Hawke, Lee M Ellis, Rajat Bhattacharya

Faculty, Staff and Student Publications

Simple Summary

In this study, we report the effects of depleting cytospin-A (CYTSA), also known as the sperm antigen with calponin homology and coiled-coil domain (SPECC1L) protein, on the proliferation and migration of colorectal cancer (CRC) cells. Mutations in this protein have been previously linked to different developmental disorders. In our studies, depletion of CYTSA in various CRC cells led to significant decreases in proliferation, increases in cell death, and increased formation of multinucleated cells. Knocking down CYTSA also led to severe inhibition of CRC cell migration and invasion. These effects could be related to a significant decrease in the …

Convection Enhanced Delivery Of The Oncolytic Adenovirus Delta24-Rgd In Patients With Recurrent Gbm: A Phase I Clinical Trial Including Correlative Studies, Erik H P Van Putten, David T Curiel, Et Al

Open Access Publications

PURPOSE: Testing safety of Delta24-RGD (DNX-2401), an oncolytic adenovirus, locally delivered by convection enhanced delivery (CED) in tumor and surrounding brain of patients with recurrent glioblastoma.

PATIENTS AND METHODS: Dose-escalation phase I study with 3+3 cohorts, dosing 107 to 1 × 1011 viral particles (vp) in 20 patients. Besides clinical parameters, adverse events, and radiologic findings, blood, cerebrospinal fluid (CSF), brain interstitial fluid, and excreta were sampled over time and analyzed for presence of immune response, viral replication, distribution, and shedding.

RESULTS: Of 20 enrolled patients, 19 received the oncolytic adenovirus Delta24-RGD, which was found to be safe and feasible. …

April 14, 2022, James Madison University

The Breeze, 2020-

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

Kenyon Collegian - April 14, 2022

The Kenyon Collegian

No abstract provided.

Acceptance And Commitment Therapy For Obsessive Compulsive Disorder In A Brazilian Context: Treatment Of Three Cases, Luana D. Laurito, Carla Pereira Loureiro, Livi Faro, Rafaela Venâncio Dias, Bianca Torres, Maria Eduarda Moreira-De-Oliveira, Samara Dos Santos-Ribeiro, Gabriela B. De Menezes, Leonardo F. Fontenelle, Carter H. Davis, Michael P. Twohig

Psychology Faculty Publications

Previous research indicates that a combination of Acceptance and Commitment Therapy (ACT) and Exposure and Response Prevention (ERP) is an effective treatment for obsessive-compulsive disorder (OCD). However, there are no studies to date of ACT for OCD in Latin American populations. Because socio-cultural context influences OCD symptomatology, it is worth adapting and testing ACT for OCD in such cultures. Three patients seeking treatment for OCD at a public health center in Rio De Janeiro, Brazil were treated with 16 sessions of ACT and ERP. All participants showed decreased OCD scores from baseline to post-treatment that remained lower at follow-up, suggesting …

School Of Nursing News, Georgia Southern University

Nursing: News & Publications (2013-2023)

• Nursing Students Awarded Scholarships

Biophilic Design In Higher Education: Exploring Nature-Based Design Inclusion In Classrooms, Danielle Burton

Honors College Theses

This study investigated how biophilic design (nature-based design) optimizes one's well-being within a classroom learning environment. It is necessary to understand how a student’s performance in higher education depends on the environment. Research supports that when students have access to daylight, feel a sense of belonging and well-being in their classrooms they are able to perform at higher levels. Using a semi-experimental method, a classroom was assessed. Classes using this classroom were surveyed at the beginning of class and at the end of the same class time. The concurrent mixed method sequential design included both quantitative and qualitative data and …

The George-Anne, Georgia Southern University

The George-Anne

• GS DRAG SHOW
• Campus Life
• Reflector Rewind
• Drunk driver crashes into Georgia Southern Pond
• First Friday: Downtown art Festival
• DRAG SHOW
• Caribbean Airways Carnival Fashion Show
• T-Pain Concert: Here's Everything You Need To Know

Physician's Attitudes On Pulmonary Rehabilitation Following Covid-19: A Brief Perspective From A Developing Country, Ivan Cherrez-Ojeda, Emanuel Vanegas, Miguel Felix, María José Farfán Bajaña, Azza Sarfraz, Zouina Sarfraz, Genesis Camacho, Alanna Barrios-Ruiz, Jack Michel

Department of Paediatrics and Child Health

Despite the uncertainty about the follow up of COVID-19 survivors, there is a growing body of evidence supporting specific interventions including pulmonary rehabilitation, which may lead to a reduced hospital stay and improved overall respiratory function. The aim of this short report was to assess the attitudes toward pulmonary rehabilitation following COVID-19 among Ecuadorian physicians. A cross-sectional study was conducted, in which a 5-question survey was used to assess the level of agreement to specific statements with a 5-point Likert scale. Out of the 282 participants, 48.2% (n=136) were male, with a mean of 12.6 (SD=11.3) years of experience. More …

Diagnostics & Therapeutic Sciences, Georgia Southern University

Clinical Sciences: News & Publications (2018-2023)

• Faculty Show Support

Control Of Orthodontic Tooth Movement By Nitric Oxide Releasing Nanoparticles In Sprague-Dawley Rats, Derrick Crawford, Tommy C. Lau, Megan C. Frost, Nan E. Hatch

Michigan Tech Publications, Part 1

Orthodontic treatment commonly requires the need to prevent movement of some teeth while maximizing movement of other teeth. This study aimed to investigate the influence of locally injected nitric oxide (NO) releasing nanoparticles on orthodontic tooth movement in rats. Materials and Methods: Experimental tooth movement was achieved with nickel-titanium alloy springs ligated between the maxillary first molar and ipsilateral incisor. 2.2 mg/kg of silica nanoparticles containing S-nitrosothiol groups were injected into the mucosa just mesial to 1st molar teeth immediately prior to orthodontic appliance activation. NO release from nanoparticles was measured in vitro by chemiluminescence. Tooth movement was measured using …

A Photography-Based, Social Media Walking Intervention Targeting Autonomous Motivations For Physical Activity: Semistructured Interviews With Older Women, Michael C Robertson, Maria Chang Swartz, Ursela Christopherson, Jason R Bentley, Karen M Basen-Engquist, Debbe Thompson, Elena Volpi, Elizabeth J Lyons

Faculty, Staff and Students Publications

BACKGROUND: Older adult women are at risk for negative health outcomes that engaging in sustained physical activity can help prevent. However, promoting long-term maintenance of physical activity in this population has proven to be a challenge. Increasing autonomous motivations (ie, intrinsic, integrated, and identified regulations) for physical activity may facilitate enduring behavior change. Digitally delivered games for health that take a celebratory technology approach, that is, using technology to create new ways to experience valued behaviors and express valued beliefs, may be a useful way to target autonomous motivations for physical activity. Formative research with the target population is needed …

Burden Of Type 2 Diabetes And Associated Cardiometabolic Traits And Their Heritability Estimates In Endogamous Ethnic Groups Of India: Findings From The Indigenius Consortium, Vettriselvi Venkatesan, Rector Arya, Juan Carlos Lopez Alvarenga, Krishna K. Sharma, Roy G. Resendez, Juliet A. Ezeilo, Marcio Almeida, Srinivas Mummidi, John Blangero, Ravindranath Duggirala

School of Medicine Publications

To assess the burden of type 2 diabetes (T2D) and its genetic profile in endogamous populations of India given the paucity of data, we aimed to determine the prevalence of T2D and estimate its heritability using family-based cohorts from three distinct Endogamous Ethnic Groups (EEGs) representing Northern (Rajasthan [Agarwals: AG]) and Southern (Tamil Nadu [Chettiars: CH] and Andhra Pradesh [Reddys: RE]) states of India. For comparison, family-based data collected previously from another North Indian Punjabi Sikh (SI) EEG was used. In addition, we examined various T2D-related cardiometabolic traits and determined their heritabilities. These studies were conducted as part of the …

Cs1 Car-T Targeting The Distal Domain Of Cs1 (Slamf7) Shows Efficacy In High Tumor Burden Myeloma Model Despite Fratricide Of Cd8+Cs1 Expressing Car-T Cells, Julie O'Neal, Julie K Ritchey, Matthew L Cooper, Jessica Niswonger, L Sofía González, Emily Street, Michael P Rettig, Susan W Gladney, Leah Gehrs, Ramzi Abboud, Julie L Prior, Gabriel J Haas, Reyka G Jayasinghe, Li Ding, Armin Ghobadi, Ravi Vij, John F Dipersio

2020-Current year OA Pubs

Despite improvement in treatment options for myeloma patients, including targeted immunotherapies, multiple myeloma remains a mostly incurable malignancy. High CS1 (SLAMF7) expression on myeloma cells and limited expression on normal cells makes it a promising target for CAR-T therapy. The CS1 protein has two extracellular domains - the distal Variable (V) domain and the proximal Constant 2 (C2) domain. We generated and tested CS1-CAR-T targeting the V domain of CS1 (Luc90-CS1-CAR-T) and demonstrated anti-myeloma killing in vitro and in vivo using two mouse models. Since fratricide of CD8 + cells occurred during production, we generated fratricide resistant CS1 deficient Luc90- …

Literature Review On The Discrete Element Method In Asphalt Mixtures, Hui Yao, Mei Xu, Junfu Liu, Yu Liu, Jie Ji, Zhanping You

Michigan Tech Publications, Part 1

Asphalt mixtures are commonly used in pavement engineering, especially for highway construction. The mechanism exploration and analysis of pavement distress are the main challenges for researchers and industry managers. Thereby, it is important to understand their properties and interaction mechanisms in asphalt mixtures. It is difficult to conduct some sophisticated or microscale tests in the laboratory, and numerical simulation and virtual tests can be solutions for these cases with low costs. The Discrete Element Method (DEM) is a promising tool for researchers to undertake these tasks. This paper mainly summarized and analyzed the research progress and development prospect of DEMs …

Infrastructure Investment And European Economic Growth, John Ziolo

Global Tides

As the global economy continues to recover from the impacts of Covid-19, there is significant discussion among policymakers as to the best mechanisms to stimulate recovery. One of those mechanisms is infrastructure investment. There is a large contingent of policymakers who believe that large, immediate spending on infrastructure will lead to significant economic growth. While another group is concerned about the secondary effects of such large government spending packages. With global economies still digging out of the covid shock and supply chains struggling to keep up with demand, there is no better time to explore the topic. This paper then …

Initial Investigation Of The Chemical Contribution Of Hemp To Beer Aroma, Caitlyn Hunt

Undergraduate Research Competition

As the availability and consumer interest in hemp materials increases, the production and consumption of products incorporating hemp and CBD oil has increased. The industrial hemp market has seen a steady increase in value of the market and is projected to reach 26.6 billion USD. South Carolina has seen an increase in the cultivation of hemp and the production of CBD oil. There has been some interest in the market for alternative uses for both raw hemp and the leftover material following the CBD oil extraction process. This interest is a result of hemp-flavored beers in the market. The use …

Microplastic Concentration Analysis Of The Atlantic Sand Fiddler Crab (Leptuca Pugilator) In Murrells Inlet, South Carolina, Caroline Conner

Undergraduate Research Competition

Microplastics pose a great threat to the natural environment, a threat not aided by their increasing abundance in marine waters. To assess how this is affecting our local area, I examined the microplastic concentration in fiddler crabs, a keystone species in intertidal zones, from two marsh systems in Murrells Inlet. The quantity, color, and type of microplastic found were recorded from each of the 120 crabs sampled. This information is revelant not only in monitoring the health of a species that plays a major role in nutrient recycling and prevention of anoxic conditions, but also as a caution to us. …

Identification And Characterization Of Small Regulatory Rna In Streptococcus, Klea Hoxha, William C. Oakes Iii, Nicole M. Ward, L. Brooke Busby

Undergraduate Research Competition

Background: The human gut is a rich habitat for a diverse population of bacteria. These bacteria play a vital role in a multitude of functions. They affect immune responses, metabolism, and even neurological activities. Some inhabitants of the gut biome include the lactic acid bacteria: Streptococcus thermophilus, Lactobacillus acidophilus, and Lactobacillus bulgaricus. These bacteria are essential members of the flora and are non-pathogenic, however, some of their relatives like Streptococcus pyogenes cause severe diseases such as flesh-eating disease. The metabolic functions of these bacteria are mediated by small regulatory RNAs (sRNAs), which are noncoding RNA sequences that fold into complex …

Sustainable Planning, Protecting Social, Economic, And Environmental Interests Of Coastal Communities, Daniel O'Hara

Undergraduate Research Competition

Understanding the connection between humans and wetland environments is imperative to coastal planning. This project looks to gather policy and scientific information from local, regional, federal, and international levels regarding wetland protection and preservation to improve policies and practices in coastal areas and create more sustainable and healthier environments. Sustainable planning in coastal communities includes connecting humans and nature through low-impact developments, using native plant species, non-impervious surfaces, and adequate buffers between developments and water sources. Successful coastal planning and development can help ensure that economic, social, and conservation interests are protected. Wetlands represent 5.5% of the total land area …

Detecting Potential Neurotoxic Pseudo-Nitzchia Species In The Grand Strand, Chesney Price, Sean Ferrano

Undergraduate Research Competition

Pseudo-nitzschia is a globally distributed diatom genus which contains 26 neurotoxin (domoic-acid) producing species. In shallow coastal waters these diatoms are associated with both the development of harmful algal blooms and the bioaccumulation of toxins in shellfish that can impact human health. Environmental DNA (eDNA) samples drawn from the public shellfish harvesting area at Huntington Beach State Park (SC) during the summer of 2021 were PCR- screened for Pseudo-nitzschia species using genus specific primers. The sequences of the recovered amplicons are used to molecularly characterize the species of Pseudo-nitzschia present and their potential to produce domoic acid.

A Step In The Search For Arboviruses: Determining Blood Meals Eaten By Mosquitoes, Carson Mickey, Olivia Shirley, Elody Bensch

Undergraduate Research Competition

Mosquitos are known to spread diseases throughout communities, including viruses, referred to as arboviruses. In 2017, DHEC reported 158 incidents of arboviruses in South Carolina, including West Nile, Dengue Fever, and Zika virus. The infections rate was up from the year before when 124 incidents of arboviruses were reported. Monitoring these infected mosquitos can be an asset for proper health protection in our community. Understanding what the mosquitoes are feeding on can help us better monitor the zoonosis threats that our community faces. A series of primers have been developed that target unique sequences in the cytochrome b gene in …

Decipher Reliable Covid-19 Related Information Among College Students, Emily Ackershoek

Undergraduate Research Competition

On March 11, 2020 the world changed forever. The World Health Organization declared COVID- 19 a global pandemic. Nearly two years later with numerous mutations of COVID-19 and with medical advancements of vaccines we are still living in a pandemic. This project will further decipher reliable COVID-19 related information among college students. With more downtime due to the pandemic and classes being shifted to virtual, more and more students are downloading popular social media apps like TikTok to cope with the lockdown. Many public health related agencies are taking advantage of the opportunity of using TikTok to share COVID-19 related …

Eta Sigma Gamma - Georgia Southern University Chapter: Breast Cancer Awareness Health Communication Plan, Jill Johns, Omolola Okunromade

Eagle Showcase: Excellence in Service-Learning (Archived)

The health communication plan was used to evaluate public health communication and advocacy promotion by efficiently increasing awareness about breast health and preventive services such as mammography screening among college students and women eligible for breast cancer screening. The communication plan was targeted towards empowering the Georgia Southern University chapter of Eta Sigma Gamma (ESG) members and other college students to act as health advocates by virtually disseminating information through the Facebook platform to their peer groups and social networks including friends and families in their community.

The purposes of the program evaluation and implementation measurement were to: 1) monitor …