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Visionary Metamorphosis In The Yogavāsiṣṭha: A Transpersonal Approach To The Existential Crisis, Caitlyn Lauren Selve

LMU Theses and Dissertations

This paper presents an unconventional approach to the existential crisis according to the transpersonal psychology of the eleventh century text, Yogavāsiṣṭha. An existential crisis is a general term used to signify a subjective experience of emotional distress as it relates to certain objective realities of human existence. This paper builds off key concepts (“givens”) from the field of existential psychotherapy, including death, isolation, freedom, and meaninglessness, provided by psychoanalyst Irvin D. Yalom, illuminating how the crisis is addressed in contemporary psychotherapeutic settings. Brief attention is given to the Western academic roots of existential psychotherapy, including areas of continental philosophy and …

Ciliate Endosymbiont Imaging Methodology, Aidan Boving, Roxanne Beinart

Senior Honors Projects

Ciliates, a phylum of diverse microbial eukaryotes, are found in a wide range of environments, including anoxia. Anaerobic ciliates host intracellular methanogenic archaea – a unique type of symbiosis. Despite their importance, anaerobic ciliates and their symbiotic relationships remain understudied. Included in this is the ability to image and quantify the intracellular methanogenic symbionts in a precise, timely and replicable procedure. This project aimed to improve the current fluorescence microscopy methodology used for endosymbiont quantification. The proposed method is intended for use with the Opera Phenix, a high throughput spinning disk confocal microscope which can count large amounts of individual …

Representing Neurodivergent Children In Fiction, Summer Calvert

Senior Honors Projects

SUMMER CALVERT (Psychology) Representing Neurodivergent Children in Fiction Sponsor: Kathleen Webster (Psychology) To recognize aspects of the self within the other is a goal universal to the human experience. The ability to relate to our peers grants us the dissuasion of insecurities or loneliness that might otherwise fester within our minds. Fictional characters and stories can have a similar effect on us. For this reason, the importance of neurodiverse representation in children’s books cannot be understated. When it comes to developmental disorders, many children may go undiagnosed until adolescence or even adulthood; this does not mean they aren’t struggling, or …

The Impacts Of The United States Healthcare System On French-Speaking Immigrants: A Shorty Story, Allison Vanasse

Senior Honors Projects

Stories are a powerful tool that can be used to educate others on topics requiring attention in the world, such as healthcare. In the United States, the structure of the current healthcare system affects disadvantaged populations and minority groups in adverse ways, making adapting to and living under this system difficult. This project brings to light these issues in the form of a short story. French speaking-immigrants of various ages, countries of origin, and perspectives were interviewed regarding their experiences with the U.S. healthcare system. Five individual interviews were conducted over the phone lasting 15-30 minutes each in order to …

The Future Is Female, Tori Hansen

Senior Honors Projects

Historically, both within the United States and globally, women have not entered into science, technology, engineering, or mathematics (STEM) associated fields at the same rate as men. Several explanations have been set forth to understand this gender gap, most of them centering around women not being encouraged to go into STEM. In recent years, the percentage of women STEM workers has exponentially increased, but women still make up a minority of STEM workers. However, with women’s enrollment in college and graduate school increasing, and men’s enrollment dropping, STEM fields may start becoming predominantly women. Thus, the goal of this study …

Assessment Of The University Of Rhode Island's Dining Halls And Student Perceptions Of On-Campus Dining, Maria Cherry

Senior Honors Projects

University dining halls are understudied food environments that affect student diet quality. This study (1) assessed dining hall offerings at the University of Rhode Island (URI) using the Partnership for a Healthier America’s Healthier Campus Initiative (PAHA) criteria for healthier campus food environments and (2) evaluated student perceptions of the dining hall through a campus-wide survey (n=165). We evaluated breakfast, lunch, and dinner using spring cycle menus (16 weeks in 2019 and 4 in 2021) from two full-service dining halls totaling 29 meals in 2019, and 84 meals in 2021 to determine adherence with PAHA criteria for availability of: 1) …

How Did Covid-19 Impact The Mental Health Of Nurses, Pamela Bedoya

Senior Honors Projects

No abstract provided.

Physiological Mechanisms Of The Impact Of Heat During Pregnancy And The Clinical Implications: Review Of The Evidence From An Expert Group Meeting, Louisa Samuels, Britt Nakstad, Nathalie Roos, Ana Bonell, Matthew Chersich, George Havenith, Stanley Luchters, Louise-Tina Day, Jane E. Hirst, Tanya Singh

Population Health, East Africa

Many populations experience high seasonal temperatures. Pregnant women are considered vulnerable to extreme heat because ambient heat exposure has been linked to pregnancy complications including preterm birth and low birthweight. The physiological mechanisms that underpin these associations are poorly understood. We reviewed the existing research evidence to clarify the mechanisms that lead to adverse pregnancy outcomes in order to inform public health actions. A multi-disciplinary expert group met to review the existing evidence base and formulate a consensus regarding the physiological mechanisms that mediate the efect of high ambient temperature on pregnancy. A literature search was conducted in advance of …

Assessment Of Soil, Water Contamination And Land Cover Changes In The Urban And Suburban Watersheds Of Houston, Texas, Felica Rena Davis

Dissertations (2016-Present)

Intense urbanization and increased anthropogenic activity are two important factors contributing to the decline of soil and water quality in Houston watersheds, which poses a great environmental and human health risks. This study, therefore, was designed to: 1) determine nutrient and metal concentrations in soil and water samples along Carpenters Bayou (CaB), Cedar Bayou (CB), Sims Bayou (SB), Spring Creek Bayou (SC) and Vince Bayou (VB), 2) analyze land cover changes in watersheds using Landsat image analysis and 3) evaluate socio-economic characteristics and human health risks for each watershed. Soil and water samples were collected from three different locations with …

Factors Related To Teachers, Students, And Schools And Reading Achievement Of Middle School Students, India Danielle Elliott

Dissertations (2016-Present)

Low reading achievement is an issue that plagues school systems across the United States. It is well established that students, teachers, and school styles have an impact on students’ reading ability and performance. This study aims to determine whether student and teacher demographics along with school-related factors significantly predict reading achievement in middle school. Specifically, this study investigates student gender, student ethnicity, teacher gender, teacher ethnicity, school curriculum, and school schedule as it relates to middle school scores on the reading component of the State of Texas Assessments of Academic Readiness (STAAR) test. To test whether or not three hypotheses …

Hbcu Athletic Administrators' Perception Toward Creating A Graduate Level Curriculum For Directors Of Athletics, Kevin Granger

Dissertations (2016-Present)

The purpose of this study was to investigate historically Black colleges and universities (HBCUs) athletic administrators (i.e., Directors of Athletics, Senior Women Administrators, Commissioners) perceptions of curriculum development and design of a graduate (doctoral) level curriculum for athletic programs. Few studies were reported in the literature of researchers investigating variables affecting the operation, effectiveness and curriculum development of athletics at HBCUs. Athletics curriculum continues to be debated amongst this discipline’s educators. Athletic directors (ADs) in institutions of higher education are the chief administrators of their respective athletic departments. Davis (2002) explains that ADs are consequently praised for the success or …

Amelioration Of Acrolein Effects On The Small Intestine Of Rats By Curcumin And Compound 20, Syntia Engiasa Kwende

Dissertations (2016-Present)

Acrolein is an unsaturated aldehyde which produce chemicals used as an intermediate reactive aldehyde in the chemical industry. The primary component of acrolein, is derived from the incomplete combustion of wood, plastic, fossil fuels, the main component of cigarette smoke, the burning of fats and overheating of oil. The purpose of this research is to investigate whether curcumin and compound 20 prevents the induction of inflammatory and oxidative response caused by acrolein in the small intestine. Curcumin is the yellow pigment, lipophilic polyphenol substance that gives turmeric the medicinal properties. It can also define as the primary bioactive substance in …

Discovery Of Ojt008 As A Novel Inhibitor Of Mycobacterium Tuberculosis, Collins Chidi Onyenaka

Dissertations (2016-Present)

Despite recent progress in the diagnosis of Tuberculosis (TB), the chemotherapeutic management of TB is still challenging. Mycobacterium tuberculosis (Mtb) is the etiological agent of TB, and TB is classified as the 13th leading cause of death globally [WHO 2021]. 558,000 people were reported to develop multi-drug resistant TB globally [WHO 2020]. Our research focuses on targeting Methionine Aminopeptidase (MetAP), an essential protein for the viability of Mtb. MetAP is a metalloprotease that catalyzes the removal of N-terminal methionine (NME) during translation of protein [Giglione et al., 2003]. This essential role of MetAPs makes this enzyme an auspicious target for …

Preclinical Development Of A Novel Antileishmanial Agent Ojt007: Bioanalytical Assay, In Vitro Studies And Pharmacokinetics, Maria Eugenia Rincon-Nigro

Dissertations (2016-Present)

Current treatments for cutaneous leishmaniasis suffer from toxic side effects, high cost, parenteral administration, and drug resistance. Thus, there is a critical need to develop oral drugs for the treatment of leishmaniasis. OJT007 is a novel class of drug with potent antiproliferative effects against Leishmania Major. The purpose of this project is to conduct preclinical drug development studies for OJT007 including bioanalytical assay development, pre-formulation studies, in vitro hepatic drug metabolism and in vivo pharmacokinetics. A sensitive, specific, and reproducible ultra-high performance liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed and validated. The separation was achieved on a UPLC BEH …

Utility Of The 13c-Pantoprazole Breath Test As A Cyp2c19 Phenotyping Probe For Children, Keith Feldman, Gregory L. Kearns, Robin E. Pearce, Susan M. Abdel-Rahman, J Steven Leeder, Alec Friesen, Vincent S. Staggs, Andrea Gaedigk, Jaylene Weigel, Valentina Shakhnovich

Manuscripts, Articles, Book Chapters and Other Papers

The 13 C-pantoprazole breath test (PAN-BT) is a safe, noninvasive, in vivo CYP2C19 phenotyping probe for adults. Our objective was to evaluate PAN-BT performance in children, with a focus on discriminating individuals who, according to guidelines from the Clinical Pharmacology Implementation Consortium (CPIC), would benefit from starting dose escalation versus reduction for proton pump inhibitors (PPIs). Children (n = 65, 6-17 years) genotyped for CYP2C19 variants *2, *3, *4, and *17 received a single oral dose of 13 C-pantoprazole. Plasma concentrations of pantoprazole and its metabolites, and changes in exhaled 13 CO2 (termed delta-over-baseline or DOB), were measured 10 times …

The Effects Of A Telehealth Exercise Intervention On Balance In Adults With Down Syndrome, Mark Barton, Kristina Guerrero, Andrew Martinez, Alexandria Umagat

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background: People with Down syndrome (Ds) often present with balance deficits, which compromise their safety during daily activity. While evidence shows that exercise can improve balance in the Ds population, it is unclear if a telehealth method will elicit similar benefits. We aimed to examine the effects of a virtual exercise program on balance in adults with Ds.

Methods: Twenty participants completed a 12-week telehealth exercise program based on the Mann Method. Balance testing took place before and after the intervention, which included: Timed Up and Go (TUG), Modified Clinical Test of Sensory Interaction in Balance (MCTSIB), Frailty and Injuries: …

Diagnostic Ultrasound As A Reliable Tool To Measure Multifidus Thickness, Katherine Shigemoto, Valeria Garcia Arteaga, Jessie Peterson, Nathan Gentry

UNLV Theses, Dissertations, Professional Papers, and Capstones

Introduction: Lower back pain (LBP) is a recurrent issue in the general population, though it is generally seen 2-3 times more frequently in those who undergo transfemoral amputations, being considered worse than phantom limb or residual pain. It is suggested that LBP is more common in those who have a transfemoral amputation than those who have a transtibial amputation. Research thus far has seemed to focus on identifying links between unilateral amputation and LBP rather than bilateral.

The multifidus muscle is the most important dynamic stabilizer of the lumbar spine, accounting for two- thirds of lower lumbar segmental stability. A …

Physical Therapy Alumni Rural Employment Assessment, Karen Aleyda Santos, Nikkita Jacob Crozier

UNLV Theses, Dissertations, Professional Papers, and Capstones

Introduction and Purpose: The University of Nevada, Las Vegas Doctor of Physical Therapy program (UNLVPT) encourages rural and underserved employment by requiring students to complete one clinical experience in either a rural or underserved setting. Students who participate in rural clinical experiences may be more likely to practice in rural settings. UNLVPT also assesses rural interest level during each student’s education. The purpose of this study was to determine if relationship exists between students’ pre- or post-clinical experience rural interest level and their practice location within the first two years after graduation. We hypothesized that an interest in rural practice …

Brain And Spinal Cord Adaptations Associated With Patellofemoral Pain: A Systematic Review And Meta-Analysis, Kara Meske, Savanna Budge Huerta, Austin Madriaga, Derrick Nguyenton

UNLV Theses, Dissertations, Professional Papers, and Capstones

Objective: To evaluate the evidence for altered cortical and spinal cord functions in individuals with patellofemoral pain (PFP).

Methods: We conducted a comprehensive search of databases to appraise and analyze the studies published prior to December 10, 2021 that examined spinal reflex excitability measured using Hoffmann reflex (H-reflex) amplitudes, corticospinal excitability measured using transcranial magnetic stimulation (TMS)-elicited motor evoked potential (MEP) amplitudes, motor threshold (MT), or stimulus-response (SR) curves, cortical reorganization assessed using TMS cortical mapping or structural magnetic resonance imaging (MRI), or functional changes of the brain assessed using functional MRI (fMRI) in individuals with PFP.

Results: Eight studies …

Political Discussion And Disagreement: Seeking Validation Through News Media, Michael Carmona

UNLV Theses, Dissertations, Professional Papers, and Capstones

This study explores how often individuals discuss politics with family/friends and acquaintances, how often individuals are exposed to disagreement during those discussions, the strategies they use to respond to political disagreement, and the use of news media following those disagreements. Through the lens of Uses and Gratifications theory, this study examined these elements through an online survey of U.S. adults. The results of this study did not support Hopmann’s, Bjarnøe’s, and Wonneberger’s findings about the relationship between the frequency of political disagreement and the strategies for responding to that disagreement. This study highlights how the discussions and disagreements we have …

Radiomic Features To Predict Overall Survival Time For Patients With Glioblastoma Brain Tumors Based On Machine Learning And Deep Learning Methods, Lina Chato

UNLV Theses, Dissertations, Professional Papers, and Capstones

Machine Learning (ML) methods including Deep Learning (DL) Methods have been employed in the medical field to improve diagnosis process and patient’s prognosis outcomes. Glioblastoma multiforme is an extremely aggressive Glioma brain tumor that has a poor survival rate. Understanding the behavior of the Glioblastoma brain tumor is still uncertain and some factors are still unrecognized. In fact, the tumor behavior is important to decide a proper treatment plan and to improve a patient’s health. The aim of this dissertation is to develop a Computer-Aided-Diagnosis system (CADiag) based on ML/DL methods to automatically estimate the Overall Survival Time (OST) for …

Sight Deprivation And Metabolic Effects During The Ymca Bench Press Test, Kyle Cruz

UNLV Theses, Dissertations, Professional Papers, and Capstones

Several studies have investigated the effect of sensory deprivation, particularly sight. However, very few have demonstrated the impact of sight deprivation while exercising to cadence blindfolded. This study aimed to determine exercise performance during a common muscular endurance evaluation, the YMCA Bench Press Test (YBPT), while blindfolded compared to a sighted condition. Twenty-five healthy participants (11 male, 14 female, 168 ± 7.7cm, 68 ± 11.7kg, 23 ± 7.5% fat mass) were recruited from the University of Nevada, Las Vegas student populations and communities. After a YBPT familiarization session, participants completed testing in a counterbalanced order, following the same procedures. A …

Healthcare Screenings In The Occupational And Workplace Setting: Taking Control Over Blood Pressure, Darryl W. Horton

UNLV Theses, Dissertations, Professional Papers, and Capstones

Undiagnosed hypertension continues to be a growing concern worldwide leading to cardiovascular disease and other chronic illnesses and can contribute to death. The prevalence of hypertension continues to increase even with guidelines on screening, hypertension education, disease prevention, disease maintenance, and management. The purpose of this project was to determine if the implementation of a workplace blood pressure screening program would improve hypertension knowledge and reduce the burden of hypertension within workplace. A descriptive, cross-sectional design using convenience sampling was conducted. Participants were screened by measuring blood pressures, and the Hypertension Evaluation of Lifestyle Management scale (HELM) was utilized to …

Comparative Expression Of Exosome-Derived Dental Pulp Stem Cell (Dpsc) Microrna, Matthew Hunsaker

UNLV Theses, Dissertations, Professional Papers, and Capstones

Introduction: Dental pulp stem cells (DPSC) are pluripotent stem cells capable of differentiating into several tissue types. Several studies have demonstrated DPSC can be extracted from deciduous and permanent teeth, including third molars (wisdom teeth) - however, much less is known regarding the factors that determine and regulate pluripotency and differentiation responsiveness among these harvested DPSC. Recent evidence has suggested small, non-coding microRNAs mediate (in part) differentiation and self-renewal among some stromal and hematopoetic stem cells, although much remains to be discovered regarding microRNA regulation of DPSC phenotypes. Based upon this information, the overall goal of this study was to …

Factors Affecting Hotel Recommendation: Before The Covid-19 Pandemic And After The Reopening, Boran Kim

UNLV Theses, Dissertations, Professional Papers, and Capstones

During the COVID-19 pandemic, numerous people lost their lives, and a lot of industries were affected. The hospitality industry was especially affected due to social distancing, travel restrictions, and safety issues. During that time, not only did customers' expectations change but their recommendation of hotels to friends and colleagues also changed. The current study used five factors (i.e., cleanliness, location, room, service, and value) to discover which factors were affecting hotel recommendation before the COVID-19 pandemic and after the reopening. This study used secondary data (online surveys) from one of the well-known integrated resorts located in the western United States. …

Researcher-Participant Privilege: Confidentiality And Qualitative Criminology, Eric Michael

UNLV Theses, Dissertations, Professional Papers, and Capstones

Research institutions have the responsibility to comply with laws that govern the oversight of all research including research with human subjects. Institutional Review Boards (IRBs) review research protocols and approve research based on the rights and safety of research subjects. When conducting qualitative criminological research, researchers must weigh ethical considerations around their methods. These methodological considerations are coupled with guiding ethical principles that are fundamental to human subject research. One major consideration regards breaking confidentiality which can bring about great risk to participants. The following thesis focuses on the ethics of researcher-participant privilege and issues that qualitative researchers have in …

The Unexpected President: An Instrumental Case Study On Women University Presidents, Jessica Soria

UNLV Theses, Dissertations, Professional Papers, and Capstones

This research study sought to examine the experiences of women university presidents. Despite the universal call for the diversification of higher education leadership, women are significantly underrepresented in the seat of the university presidency as higher rank university leadership positions are overwhelmingly occupied by white males. By interviewing women university presidents from diverse backgrounds and from different institutions, this instrumental case study examined their unique experiences. This study utilized two critical theoretical concepts to guide the study: intersectionality and gendered organizations theory.

Parental Education On Human Papillomavirus Vaccination, Marguarette J. Suprien

UNLV Theses, Dissertations, Professional Papers, and Capstones

The human papillomavirus (HPV) is a worldwide condition that produces several diseases, including cervical, anogenital, and oral cancer, among others (Fishman et al., 2014). The Center for Disease Control and Prevention (CDC; 2016a) stated that HPV is among the most reported sexually transmitted diseases in the United States. Over 150 viruses are associated with HPV, and 40 types of the virus can be spread via sexual contact, including vaginal, oral, and anal sex (CDC, 2016; CDC, 2016b; CDC, 2016c). Evidence shows that approximately 79 million individuals are infected in the United States, and 14 million Americans are infected with the …

Describing Bacterial Mutagenic Hotspots And Signatures Along With The Factors That Drive Them, Carmen Vallin

UNLV Theses, Dissertations, Professional Papers, and Capstones

In my dissertation work, I investigated bacterial mutagenesis. I asked: where do mutations occur in the bacterial genome? What types of mutations occur? What factors promote or prevent mutations? And lastly, how do the answers to these questions change depending on the bacterial life cycle (When)? I used Bacillus subtilis, a Gram-positive bacterium belonging to the phylum Firmicutes, and Escherichia coli, a Gram-negative bacterium belonging to the phylum Proteobacteria, to answer these questions. B. subtilis and E. coli are model systems that have been used to gain insights into fundamental processes of mutations and evolution for nearly ~8 decades. Here, …

Communicating Pain Unseen: Addressing Health Outcomes In Sexual Activity For Women With Endometriosis, Madison Wiese

UNLV Theses, Dissertations, Professional Papers, and Capstones

Roughly 160 million women live with endometriosis, a chronic disease involving the uterine lining shedding on the outside of the uterus causing immense physical and emotional pain (Becker et al., 2020). One common symptom of endometriosis is dyspareunia, or painful sex (Ballard et al., 2008). This study aims to uncover how gender expectations from society impact women with endometriosis specifically in sexual encounters. Informed by the traditional sexual script theory and sexual script theory, the study examines how traditional gender norms might influence women’s prioritization of their own health needs as well as the physical, emotional, and relational health outcomes …