Digital Commons Network^™

Mathematical Modeling Of Potassium Modulated Viral Infection, Zaira Elizabeth Mather

Open Access Theses & Dissertations

In recent years, there is a growing interest in the investigation of using potassium to treat virus infections. In the region of infection, there is a biological observation of extracel- lular potassium level being typically very low whereas the intracellular potassium levels are much higher. There are numerous biological studies showing that elevated potassium levels in the extracellular membrane tends to block virus infections. A recent effort in this direction is a collaborative research conducted by mathematicians and biologists from the University of Texas at El Paso, New Mexico State University, and the University of New Mexico, where we develop …

Only The Eyes: A Novel, Jason Michael Palomo

Open Access Theses & Dissertations

Only the Eyes revolves around a series of murders that take place in the oil-rich United Arab Emirates, the government of which suppresses the media to maintain the nation's reputation as a safe, innovative tourist destination. After the murders are leaked to the international press and can no longer be ignored, the Sheikhs of the country. decide to procure an investigative consultant through manipulative means to help them capture the unknown suspect. Former-Special-Agent Ramon Del Toro is now a true-crime writer, and he reluctantly takes on the difficult task of creating a psychological profile of the suspect, much to the …

Establishing The Construct And Concurrent Validity Of Psychological Cumulative Stress And The Moderating Effect Of Protective Factors To Drinking Outcomes, Carlos Portillo

Open Access Theses & Dissertations

Previous studies have examined the associations between types of psychological stress and alcohol consumption but have not adequately examined psychological stress from a cumulative perspective. The present study sought to examine if self-report measures representing chronic stress, acute stress, life events, traumatic life events, and daily hassles throughout one’s lifetime were associated with drinking outcomes obtained from an online sample of at-risk drinkers reporting drinking patterns in the previous 90 days. Furthermore, the present study sought to examine if an index of protective factors moderate the effects of psychological stress on drinking outcomes. It was hypothesized that (1) the measures …

The Experience Of Immigration And Aging On The Health Of Older Adults In The El Paso, Texas, Border Region, Sonia Lizet Ramos

Open Access Theses & Dissertations

Healthcare access continues to be a problem for immigrant populations in the United States, especially for Latino immigrants at the US-Mexico border. There is limited social research examining the experience of access to health care of older adult Latino immigrants during their life course in the U.S. In U.S.-Mexico border communities, documented and undocumented residents face unique experiences when accessing health care. This thesis focuses on understanding the intersectionality of the immigration process and health care access of older adult Latino immigrants on the U.S.- Mexico. Using qualitative data collected from participants living in the County of El Paso, Texas, …

Remember When We Tore Each Other Limb From Limb?, Adam Ramsey

Open Access Theses & Dissertations

REMEMBER WHEN WE TORE EACH OTHER LIMB FROM LIMB? is a collection of short stories and surrealist prose poems. Most of these are not connected in terms of character or setting. However, there are two episodic stories that reoccur throughout the book, each of them grounded in real-life situations meant to offset the fantastical settings in which the majority of the other pieces are set. The first of these episodic stories is a series of vignettes about a character named Noah, a young man who is taking care of his elderly mother. The other is a series about a young …

Reducing Children's Exposure To Traffic-Related Pollution: Evaluating Policies And Strategies Used By Texas School Districts, Laura Schwanke

Open Access Theses & Dissertations

Children are most vulnerable to the effects of traffic-related air pollution because of their developing respiratory systems, amount of time spent outdoors, and faster rates of breathing. As one of the largest states in the U.S. in terms of both total population and number of children, Texas is a particularly important place for studying policies and strategies used by school districts to reduce childrenâ??s exposure to vehicular pollution. No previous study had examined how public school districts in Texas are attempting to mitigate the effects of traffic-related air pollution on childrenâ??s health. This thesis sought to address this knowledge gap …

Covid Synergy: A Machine Learning Approach Uncovering Potential Treatment Combinations For Sars-Cov-2, Jason Eden Sanchez

Open Access Theses & Dissertations

For more than two years, the COVID-19 pandemic has upended the lives of billions of individualsworldwide leading to disruptions in healthcare, the economy and society at large. As the pandemic enters its third year, the human impact cannot be overstated and the need to develop effective pharmaceuticals remains. Though there currently exits FDA-approved medications for COVID-19, the emergence of novel variants, such as Omicron, highlights the importance of discovering new therapies which will continue to be effective regardless of the pandemicâ??s progression. Because discovering new medications is a costly and timeintensive endeavor, my approach entails drug repurposing to test medications …

Integration Of Genetic Isothermal Amplification On Low-Cost Hybrid Paper/Polymer Microfluidic Biochips For High Sensitivity Point-Of-Care Disease Diagnosis, Hamed Tavakoli

Open Access Theses & Dissertations

Infectious diseases and cancer have been two main causes of global death and disability, leading to a significant impact on public health and economies globally. Early diagnosis of these diseases can improve prevention, treatment, and prognosis in clinical practice. However, current laboratory diagnostic approaches require expensive and bulky equipment, well-trained personnel, and time-consuming processes, which puts a great challenge to conventional methods to address, especially in resource-limited settings. Microfluidic lab-on-a-chip presents a unique opportunity for various biomedical applications due to multiple advantages such as low reagent consumption, integration, miniaturization, portability, and automation. Since different microfluidic platform substrates have their advantages …

Inflammaging: Inflammatory Biomarkers Associated With Nutrition, Metabolism And Muscle Tissue Oxygenation Relative To Sarcopenic Status In Older Adults, Marni Elise Shoemaker

Open Access Theses & Dissertations

The purpose of this study is to examine if we can differentiate inflammaging between sarcopenic and non-sarcopenic older adults by exploring if there are differences between biomarkers of inflammation and nutritional status in older adults with distinct differences in skeletal muscle mass, strength, and function, metabolic flexibility, and muscle tissue oxygenation. Twenty-one non-sarcopenic (mean±standard deviation, age = 73.1±6.2 yrs, n=5 males, n=5 females) and sarcopenic (age = 81.2±10.5 yrs, n=6 males, n=5 females) were categorized based on muscle mass and strength criteria according to the European Working Group on Sarcopenia in Older People. Body composition, handgrip and leg extension strength, …

Testimonios Of First-Generation, Multilingual, Latina Doctoral Students At The U.S.-México Border, Cynthia Carolina Terán López

Open Access Theses & Dissertations

This qualitative study is developed with the idea that the socialization experiences of Latina doctoral students are found in the socially constructed institutional culture of a university at the U.S.-México border. Furthermore, Latina doctoral students are considered active agents in their development as scholars and co-creators of culture. Thus, this study looks at Latina doctoral students’ ways of knowing as assets used to shape their experiences in a way that benefits and empowers them. Specifically, the study expands on the existing research on socialization experiences at the doctoral level to explore the understudied significance of language and being a first-generation …

Equity Driven Data Analysis For Public Transportation Planning, Gerardo Ivan Valenzuela Mendoza

Open Access Theses & Dissertations

Existing public transportation planning methods use a trip-based approach rather than a user-based approach; a user-based approach is sensitive to a broader range of planning strategies and policies, especially those that affect or take into consideration how users spend their time and resources. Even though transportation planning agencies such as Metropolitan Planning Organizations (MPOs) are required to strive for environmental and social justice, there is still a gap that needs to be filled. Urban population growth and urbanization with its impact on public planning require continuous research to address the constantly evolving challenges when it comes to transportation. As cities …

Developing And Applying Computational Algorithms To Reveal Health-Related Biomolecular Interactions, Yixin Xie

Open Access Theses & Dissertations

Computational biology is an interdisciplinary area that applies computational approaches in biological big data, including protein amino acid sequences, genetic sequences, etc., which is widely used to analyze protein-protein interactions, make predictions in drug discovery, develop vaccines, etc. Popular methods include mathematical modeling, molecular dynamics simulations, data science mythology, etc. With the help of computational algorithms and applications, drug development is much faster than traditional processes, as it reduces risks early on in a drug discovery process and helps researchers select target candidates that have the highest potential for success. In my doctoral research, I applied multi-scale computational approaches to …

Feasibility Of Utilizing Spot-Scanning Proton Arc (Sparc) Therapy For Whole Lung Irradiation, Lewei Zhao, Gang Liu, An Qin, Di Yan, Craig Stevens, Xiaoqiang Li, Rohan Deraniyagala, Xuanfeng Ding

Conference Presentation Abstracts

Purpose or Objective We reported the first feasibility study of utilizing spot-scanning arc therapy (SPArc) whole lung irradiation for a pediatric patient to reduce cardiac toxicity. Materials and Methods A 13 year-old patient with metastatic Ewing sarcoma treated with Volumetric Modulated Arc Therapy (VMAT) in our institution was selected (Figure 1A). The clinical VMAT plan used three 360-deg arcs with 6 MV based on the Elekta HD. Intensity Modulated Proton Therapy (IMPT) plan was generated using 2 iso and 4 treatment fields (Figure 1B) based on the single field optimization approach in a clinical treatment planning system (TPS) (RayStation version …

Comparison Of Cone Mosaic Metrics From Images Acquired With The Spectralis High Magnification Module And Adaptive Optics Scanning Light Ophthalmoscopy, Niamh Wynne, Heather Heitkotter, Erica N. Woertz, Robert F. Cooper, Joseph Carroll

Biomedical Engineering Faculty Research and Publications

Purpose: To compare cone mosaic metrics derived from adaptive optics scanning light ophthalmoscopy (AOSLO) images with those derived from Heidelberg Engineering SPECTRALIS High Magnification Module (HMM) images.

Methods: Participants with contiguous cone mosaics had HMM imaging performed at locations superior and temporal to the fovea. These images were registered and averaged offline and then aligned to split-detection AOSLO images; 200 × 200-µm regions of interest were extracted from both modalities. Cones were semi-automatically identified by two graders to provide estimates of cone density and spacing.

Results: Thirty participants with contiguous cone mosaics were imaged (10 males, 20 females; age range, …

Training The Responsible Conduct Of Research And Design, Jay R. Goldberg

Biomedical Engineering Faculty Research and Publications

Students Supported by grants from the National Institutes of Health (NIH) are required to complete training in the responsible conduct of research (RCR). This training includes topics such as authorship, handling of data, reporting of results, maintaining confidentiality, and other topics related to the ethical and responsible conduct of research. It prepares students who are supported by NIH research grants for careers involving research.

Recruiting And Retaining Generation Z, Dylan Klim

Faculty and Staff Publications & Presentations

No abstract provided.

Google Translate "Schwartzfahrer" And The Exploration Of Racism And Belonging In A Different Culture, James P. Meza, Daniel Tanbakuchi, Robin Zehner, Andrea Daniel, Jianming Lau

Conference Presentation Abstracts

This project is based on the premise that observing a different culture enables a less politicized discussion of racism in the America. Using the short film "Schwartzfahrer" by Pepe Danquart, this project proposes convening focus groups to uncover layers of meaning and differing perspectives on topics that include race, identity, immigration, societal belonging-exclusion, and civic courage. The film is 12 minutes long. Participants will be asked to examine non-verbal and para-linguistic attributes portrayed. The second layer of meaning will be elicited by adding English subtitles and viewing the film again. The facilitator will elicit a list of overt racist utterances …

Scholarly Activity And Academic Writing For Practicing Clinicians, James P. Meza, Nicholus H. Yee, Ethan O. Cohen, Milan V. Pantelic, Thomas Przybycien, Tyler Russeth, Krupa Patel, Scott Baughan

Conference Presentation Abstracts

This roundtable discussion brings the executive editorial board of Clinical Research in Practice: The Journal of Team Hippocrates into direct contact with prospective authors to provide editorial support with the goal of coaching participants to be successful when submitting a manuscript to Clinical Research in Practice: The Journal of Team Hippocrates. The aims and scope of the journal focus on clinical decision science (CDS). CDS explores how the complex, interacting aspects of clinical care are described, understood, shared, and explained. This includes both biomedical and medical social sciences, in addition to other ways of understanding human experience. This is a …

Skin And Soft Tissue Infection, Children's Mercy Kansas City

Clinical Pathways (Formally Known As Clinical Practice Guidelines)

No abstract provided.

Urinary Tract Infection-Cystitis/Pyelonephritis, Children's Mercy Kansas City

Clinical Pathways (Formally Known As Clinical Practice Guidelines)

No abstract provided.

Evaluating Plant Uptake Of 4,4'-Methylenedianiline, Jeff Wight

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

4,4’-Methylenedianiline (MDA) is an important industrial chemical used primarily in the production of polyurethane. It is toxic and a suspected human carcinogen. Polyurethane is used in a wide variety of applications such as furniture cushioning, coatings, adhesives, sealants, and elastomers. Polyurethane in soil may degrade and release MDA. This is concerning due to some models predicting a high potential for MDA to be taken up by plants and stored in edible tissue, creating a possible route of exposure for humans and animals. In this project, the potential for MDA to be take up by plants was investigated in order to …

Thermodynamic Analysis Of A Novel Cycle For Nuclear Smr And Heat Transfer Performance Validation Of The Related Supercritical Working Fluids, Benjamin M. Pepper

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Currently, all operating nuclear power facilities in the U.S. follow the same general design and process: light-water reactors boil water into steam using bundles of nuclear fuel rods as a heat source, pumping that steam through a turbine which powers a generator to produce clean year-round electricity. Water is an effective coolant, but other facilities around the world have demonstrated the ability to use non-water-based coolants in nuclear reactor designs, which consequently have their own trade-offs. Some positive consequences of using different reactor designs include enhanced safety, better economics, and cheaper clean consumer energy. The work described in this paper …

Evaluation Of Human And Ecological Water Management Tradeoffs In A Seasonal Watershed With Spatially-Distributed Demands, Jesse Lee Rowles

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

River managers must balance the needs of the ecosystems that rely on the river by leaving water instream, often while also considering human demands. It is especially difficult to balance these water needs in systems that are highly seasonal and have no instream storage (e.g., reservoirs) since water cannot be stored for use throughout the year. An example of a watershed that has both of these characteristics is the South Fork Eel River in coastal northern California. In order to evaluate tradeoffs between human and ecological demands in this system, a water allocation model with water management scenarios and environmental …

Carnivoran Frugivory And Its Effect On Seed Dispersal, Plant Community Composition, Migration, And Biotic Carbon Storage, John P. Draper

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Seed dispersal by animals is important for the ecology of plants. It is particularly important to understand which animals are involved and how they move seeds differently from one another. Some seed dispersers are understudied despite ample evidence they consume fruits and seeds. This includes animals commonly referred to as carnivores in the order Carnivora. The overall goal of my dissertation was to describe the extent and quality of seed dispersal by Carnivorans, estimate important aspects of seed dispersal for a specific Carnivoran, the coyote, and estimate how differences between a coyote and songbirds affect where plants …

Artificial Intelligence And Deep Reinforcement Learning Stock Market Predictions, Andrew W. Brim

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Billions of dollars are traded automatically in the stock market every day, including algorithms that use artificial intelligence (AI) techniques, but there are still questions regarding how AI trades successfully. The black box nature of these AI techniques, namely neural networks, gives pause to entrusting it with valuable trading funds. This dissertation applies AI techniques to stock market trading strategies, but it also provides exploratory research into how these techniques predict the stock market successfully.

This dissertation presents the work of three research papers. The first paper presented in this dissertation applies a artificial intelligence technique, reinforcement learning, to candlestick …

Voces: Experiences Of Undocumented Latines, José Manuel González Vera

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The purpose of this study was to learn about the challenges that this community faced before the pandemic and how they coped through those challenges. To answer this question, I examined transcripts from group interviews collected in the state of Texas. In total, there were 67 participants, many of whom were undocumented (n = 49) while the others had a relative or friend who was undocumented. Data were analyzed by looking for common patterns and themes in the transcripts, and guided by Critical Race Theory, Latine Critical Theory, and Undocumented Critical Theory. Results suggest that psychological distress is common …

4r Nitrogen And Water Optimization Combinations For Intermountain West Field Crops, Tina Sullivan

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The concept of 4R (right source, rate, placement, and timing) management needs little introduction due to the surplus of nutrient studies in the literature for most cultivated crops. However, few studies have looked at these practices in the Intermountain West with nitrogen use, and fewer looked at 4R irrigation management. A survey was conducted to explore the interactions of nitrogen and irrigation management, test sensitivity to supply and price changes of nitrogen and irrigation for Utah and Idaho growers of small grains, corn, and potatoes, and determine the current adoption of precision agriculture options and identify the opportunities to improve. …

Cultivating Agrobiodiversity In The U.S.: Barriers And Bridges At Multiple Scales, Kaitlyn A. Spangler

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The diversity of crops grown in the United States (U.S.) is declining, causing agricultural landscapes to become more and more simplified. This trend is concerning for the loss of important plant, insect, and animal species, as well as the pollution and degradation of our environment. Through three separate but related studies, this dissertation addresses the need to increase the diversity of these agricultural landscapes in the U.S., particularly through diversifying the type and number of crops grown. The first study uses multiple, openly accessible datasets related to agricultural land use and policies to document and visualize change over recent decades. …

Automated Quality Control For In-Situ Water Temperature Sensors, Leah S. Richardson

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The identification of data not representative of the target subject for outdoor (in-situ) environmental sensors (bad data) is a topic that has been explored in the past. Many tools (such as data filters and computer models) have succeeded in providing an end user with properly identified incorrect data over 95% of the time. However, with the continuous increase in the use of automated data collection, a simple indication of the bad data may no longer provide the end user with enough information to reduce the amount of time that must be spent for manual quality control. The purpose of this …

Investigating Tourists' Decision Making And Intentions For Outdoor Recreation Participation During Early Covid-19, Prasanna Humagain

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

This dissertation aims at discerning tourists’ behaviors and decision making processes for outdoor recreation participation, during the early COVID-19 pandemic. An outdoor recreation trip is defined in this study as “a journey involving at least one overnight stay away from home, and where the purpose is to engage in recreational activities in an outdoor or natural environment.” This dissertation first explores the factors that inhibit tourists’ desires for participating in outdoor recreation trips, the strategies they apply to avoid COVID-19 transmission, and the motivational factors that induce their desires for outdoor recreation participation in the COVID-19 context. The impact of …