Digital Commons Network^™

Nerandomilast In Progressive Pulmonary Fibrosis: Data From The Whole Follow-Up Period Of The Fibroneer-Ild Trial, Marlies S Wijsenbeek, Shervin Assassi, Arata Azuma, Vincent Cottin, Anna-Maria Hoffmann-Vold, Toby M Maher, Fernando J Martinez, Justin M Oldham, Luca Richeldi, Claudia Valenzuela, Hui Gu, Ivana Ritter, Susanne Stowasser, Michael Kreuter

Faculty, Staff and Student Publications

Background: In the FIBRONEER-ILD trial in patients with progressive pulmonary fibrosis (PPF), nerandomilast 9 mg bid and 18 mg bid reduced the decline in forced vital capacity at week 52 compared with placebo (the primary endpoint). We assessed the effects of nerandomilast up to the final database lock.

Methods: Time to first acute exacerbation of ILD, hospitalisation for respiratory cause, or death (key secondary endpoint) and other time-to-event endpoints were assessed.

Results: 1176 patients, of whom 512 were taking background nintedanib, received nerandomilast or placebo. At final database lock, mean (sd) exposure to trial medication was 15.1 (5.7) months and …

The Development Of A Framework To Classify Medication Deprescribing Among Patients With Type 2 Diabetes In Primary Care Practices, Puja B Gandhi, Yoav Jacob, Joeita F Macfield, Gia Merlo, Stefanie M Meyer, Shivani S Patel, Caroline Rhéaume, Kara L Staffier, Madeline Watson, Micaela C Karlsen

Faculty, Staff and Student Publications

No abstract provided.

An Integrated Germline And Somatic Genomic Model For Coronary Artery Disease, Xiong Yang, Min Seo Kim, Xinyu Zhu, Md Mesbah Uddin, Tetsushi Nakao, So Mi Jemma Cho, Satoshi Koyama, Tingfeng Xu, Laurens F Reeskamp, Rufan Zhang, Zhaoqi Liu, Yunga A, Paul S De Vries, Ramachandran S Vasan, Eric Boerwinkle, Alanna C Morrison, Bruce M Psaty, Russell P Tracy, Susan R Heckbert, Michael H Cho, Jeong H Yun, Nicholette D Palmer, Donald W Bowden, Joanne M Murabito, Daniel Levy, Nancy L Heard-Costa, George T O'Connor, Lewis C Becker, Brian G Kral, Lisa R Yanek, Laura M Raffield, Bertha Hidalgo, Jerome I Rotter, Stephen S Rich, Kent D Taylor, Wendy S Post, Charles Kooperberg, Alexander P Reiner, Braxton D Mitchell, Sharon L R Kardia, Jennifer A Smith, Patricia A Peyser, Lawrence F Bielak, Dong Keon Yon, Hong-Hee Won, Donna K Arnett, Albert V Smith, Stacey B Gabriel, Patrick T Ellinor, Nhlbi Trans-Omics For Precision Medicine (Topmed) Consortium, Pradeep Natarajan, Minxian Wang, Akl C Fahed

Faculty, Staff and Student Publications

Multiple germline and somatic genomic factors are associated with risk of coronary artery disease, but there is no single measure of risk that integrates all information from a DNA sample. To address this gap, we develop an integrated genomic model that includes six germline and somatic genetic drivers for coronary artery disease, including polygenic risk score, genetically-proxied proteomic/metabolomic risk scores, and clonal hematopoiesis of indeterminate potential. We evaluated its predictive power in the UK Biobank (N = 391,536), and validate it using data from the TOPMed program (N = 34,177). The 10-year coronary artery disease risk based on the integrated …

Monitoring Relapse In Post-Transplant Acute Myeloid Leukemia Requires Integrated Assessment, With Flow Cytometry Showing The Highest Efficacy, Wei J Wang, Sa A Wang, Hong Fang, Qing Wei, Shimin Hu, Sanam Loghavi, Gheath Al-Atrash, Chenxuan Zang, Peng Wei, Jeffrey L Medeiros, Wei Wang

Faculty, Staff and Student Publications

No abstract provided.

March 26, 2026, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Spartan Daily, March 26, 2026, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2026

Volume 166, Issue 28

Quaker Campus, March 26, 2026 (Vol. 24, Issue 10), Whittier College

Quaker Campus

No abstract provided.

Early Literacy Footprints: Analysis Of Elementary School Students' Initial Reading Abilities Using Early Grade Reading Assessment (Egra), Novi Safitri, Rina Heryani, Angga Hadiapurwa, Atep Sujana

Bahasa dan Seni: Jurnal Bahasa, Sastra, Seni, dan Pengajarannya

Low initial reading skills are an indication of low student literacy. This research aims to analyze the early reading skills of Phase A students, which includes grades 1 and 2 of elementary school. The research used a descriptive qualitative method, involving 122 students from two elementary schools in Garut Regency, aged 6 to 8 years old. The instrument used in this study was the Early Grade Reading Assessment (EGRA) reading test. The results of the study showed that 68% of students in Phase A had early reading skills in the category of needing guidance. Meanwhile, 6.6% of students were in …

Curriculum For A Two Semester Calculus Course Specializing In Life Science And Data Science, Patrick Mcclain

LSU Master's Theses

Traditionally, introductory calculus has been designed for engineering and physics students, often leaving students majoring in data science or life sciences with a curriculum that lacks professional relevance and is overly reliant on problems that focus on computational fluency. This thesis proposes a two-semester sequence, called MATH 153X and MATH 154X, specifically tailored for the Louisiana State University (LSU) Dual Enrollment program and university-level data science and life sciences majors. By integrating modern computational tools—such as symbolic calculators and artificial intelligence (AI) tools—the proposed curriculum shifts the pedagogical focus from procedural symbolic manipulation toward conceptual literacy.

Through a series …

Comparison Of Sampling Methods For Estimation Of Aquatic Insect Diversity And Abundance Across Seasonal Gradients In A Southern U.S. River System, Albert Henry Gasperecz

LSU Master's Theses

Determination of benthic macroinvertebrate assemblage composition plays a vital role in assessment and management of lotic systems throughout the U.S. However, the validity of biomonitoring programs depends on accurate and precise measures of macroinvertebrate abundance, which in turn are dependent on sampling gears and protocols. The goal of this project was to assess how gear selection influences estimates of aquatic insect abundance and diversity, and how this selection can affect biological monitoring practices. I used 4 different gears in 3 southern Mississippi streams to aquatically and terrestrially collect aquatic insects seasonally throughout 2024. I identified and recorded all genera present …

Linguistic Realization Of Marketing Strategies In Food Discourse: A Pragmatic Study On Instagram Account, Titik Sudartinah, Emi Nursanti, Regita Sekar Arrum

Bahasa dan Seni: Jurnal Bahasa, Sastra, Seni, dan Pengajarannya

In today's digital era, speech acts are not only realized through face-to-face communication but also manifested in online interaction. One of the prominent platforms where online interaction occurs is Instagram. Nowadays, Instagram functions not only as a medium for sharing personal moments but also as a powerful business tool for promotion. This study examines (1) the types of speech acts employed in the @voilajogja culinary Instagram account and (2) how these acts manifest marketing strategies in food discourse. The study applies Searle's (1979) speech act theory and Kotler and Keller's (2021) marketing management framework within a mixed-method design. The analysis …

Proposed Standardized Nomenclature For Anomalous Aortic Origin Of A Coronary Artery: An International Multidisciplinary Initiative, Carlos M Mery, Meena Nathan, Christoph Gräni, Rajesh Krishnamurthy, Cristina Basso, Marshall L Jacobs, Julie A Brothers, Massimo A Padalino, Silvana Molossi

Faculty, Staff and Students Publications

Increasing use of advanced noninvasive imaging has provided great anatomic and morphologic details to characterize congenital coronary artery anomalies. Anomalous aortic origin of a coronary artery (AAOCA) is a subtype that may lead to myocardial ischemia with variable clinical manifestations across the lifespan. Management decision making in AAOCA is hindered by anatomic variants of differing physiologic consequences. Several systems of nomenclature have been used that lack uniformity in potentially high-risk morphologic features. The ICAAC (International Coronary Artery Anomalies Collaborative), a group of experts in coronary artery anomalies, proposes a standardized nomenclature to describe anatomy and morphologic features of AAOCA using …

March 26, 2026, James Madison University

The Breeze, 2020-

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

Domains That Influence Underrepresented Community Wellbeing And Engagement: A Literature Review, Nicole Sung, Mei Lin Chen-Lim, Phd, Rn, Ccrc, Aunja Richards, Bis, Florence Ling, Phd

Student Papers, Posters & Projects

Introduction

Inner-city neighborhoods, such as those in Philadelphia, vary in demographics, resources, access, safety, and overall health. Local non-profits that serve these communities require more understanding of the areas they serve to efficiently align resources and meet the local community needs. Community partnerships, including youth in the community, are key informants as they share lived experiences, navigate neighborhood conditions, and identify barriers and priorities.

Patiromer For Patients With Heart Failure At Risk Of Hyperkalemia: Care-Hk In Hf Registry, Omar Cantu-Martinez, Stephen J Greene, Khaja M Chinnakondepalli, Stefan D Anker, Biykem Bozkurt, Javed Butler, John G Cleland, Nihar Desai, Diederick E Grobbee, Ellie Kelepouris, Giuseppe Rosano, Tibor Kempf, Martin Schulz, Carla-Maria Brandes, Victoria Donachie, Andrew J Sauer

Faculty, Staff and Students Publications

Background: For patients with heart failure (HF), hyperkalemia (HK) may prevent optimal renin-angiotensin system inhibitor (RASi) use. Randomized trials show that patiromer, a contemporary potassium binder, reduces serum potassium (sK+) concentrations and HK, potentially enabling RASi optimization. We sought to assess the real-world effectiveness of patiromer in facilitating RASi optimization in HF patients at increased risk of HK.

Methods and results: The CARE-HK in HF (Cardiovascular and Renal Treatment in HF Patients with HK or at High Risk of HK) (NCT04864795) was a prospective registry of patients with chronic HF at increased risk of HK (prior or current …

Teaching Children Money Management, Melanie Jewkes, Amanda Christensen, Andrea Schmutz, Vincenza Vicari-Bentley, Kelan Combe, Rochelle Allen, Lauren Olsen, Jenny Weller, Mckenzie Walsh

All Current Publications

Don't fret if, as a parent, you don't feel qualified to teach your children about money. Talking about money and choices made with money (for better or worse) is a great place to start. This publication covers what and how to teach children about money management skills, and gives every-day parents ideas to start the conversation.

Montana Kaimin, March 26, 2026, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

Outcomes With Single Tremelimumab Regular Interval Durvalumab (Stride) For Unresectable Hepatocellular Carcinoma In The Us Veterans Administration, Shalini Bansal, Priya Amin, Courtney Williamson, Stephen Valerio, David Kaplan

Student Papers, Posters & Projects

Background: HIMALAYA demonstrated that STRIDE (Single Tremelimumab Regular Interval Durvalumab) significantly improved overall survival (OS) compared with sorafenib in participants with unresectable hepatocellular carcinoma (HCC). This retrospective, real-world cohort study evaluated outcomes with STRIDE in veterans with HCC. Methods: Patients diagnosed with HCC between 1 January 2008 and 28 February 2024 who received ≥1 dose of STRIDE for unresectable disease were included. Data were collected from the Veteran Affairs Corporate Data Warehouse. Safety and efficacy were evaluated overall and for subgroups of patients with Child–Pugh A versus Child–Pugh B cirrhosis, viral versus non-viral HCC, and those with versus without prior …

Transformational Leadership In Higher Education, Dr. Jewel Hale, Jr., Kristi Apostel

Tapestry: Journal of Research in Education

A crisis can highlight the critical need for resilient leadership within higher educational settings. Educational leaders encounter extraordinary difficulties, ranging from different learning options to prioritizing the well-being of both staff and students, necessitating flexible and innovative methods. By exploring how school leaders apply transformational techniques in actual educational environments, this article addresses the impact of the four I’s of transformational leadership, idealized influence, inspirational motivation, intellectual stimulation, and individualized consideration, on building educator resiliency, sustaining school effectiveness, and promoting student achievement in higher education.

Fierce Leadership-Perspectives Of Black Women Educational Leaders: A Transcendental Phenomenological Study, Janice Taylor, Dianne Reed

Tapestry: Journal of Research in Education

The authors of this transcendental phenomenological study aimed to describe the lived experiences of Black women based on their perceptions, values, and beliefs about the complexities of leadership and the kind of leadership required to succeed in their respective roles, as educational leaders. This study was framed by the adaptive leadership theory. Adaptive leadership recognizes the need for leaders to stay flexible and resilient in fast-paced environments (Nelson & Squires, 2017). The three Black women leaders in this study were fierce adaptive leaders. The information acquired from this study is significant and highlights how Black women educational leaders developed the …

Being-Their-Ship: A Presence-Based Model Of Human-Centered Leadership, Ricky J. Martinez

Tapestry: Journal of Research in Education

Being-Their-Ship describes a presence-based approach to leadership grounded in lived experience rather than positional status. Developed over years of service in rural education, the framework highlights leadership as a relational practice grounded in steadiness, quiet support, and a willingness to take responsibility for others. Drawing from autoethnography and narrative inquiry, the framework articulates four interconnected dimensions: Caring-Ship, Loving-Ship, Load-Ship, and Being-There-Ship, that define leadership not through authority but through consistent action and cultural trust. Each dimension reflects how leadership emerges when individuals become a stabilizing presence, absorb burdens that others would otherwise carry, and remain committed to a community through …

Research Literacy And Research Production Skills As Core Competencies In Leaders, Kk O'Byrne

Tapestry: Journal of Research in Education

No abstract provided.

Teaching Experience And Burnout During Remote Learning, Tony Durr, Nicole Graves, Patrick D. Hales

Mid-Western Educational Researcher

During the spring of 2020 many K-12 teacher were forced to transition their classes to remote learning environments. This study examines the extent to which teaching experience related to symptoms of burnout reported by teachers when switching instruction to remote learning during the COVID-19 pandemic. Results indicated that years of teaching experience was a significant predictor of the emotional exhaustion component of burnout, with mid-career (β = 0.966, p ≤ .001) and veteran teachers (β = 1.085, p ≤ .01) reporting significantly higher levels of emotional exhaustion compared to novice teachers. These results indicate that novice teachers experienced less burnout …

Factors For Successful Craniosynostosis Surgery Gofundme Campaigns, Annarose Taylor, Rena Atayeva, Shikha Trivedi, Phavon Sage, David Park, Brendan Podszus, Jessica Bigner, Yifan Guo

Knowledge and Creativity Expo

Introduction

Craniosynostosis surgery costs can be as high as 100,000 dollars. Even with complete insurance coverage, patients often face large out-of-pocket expenses. Thus, patients seek other financial resources. As a crowdfunding platform, GoFundMe (GFM) is one of those resources. The objective of our study was to identify GFM campaign factors associated with greater fundraising success.

Methods

GoFundMe.com was queried for: craniosynostosis, synostosis, brachycephaly, trigonocephaly, scaphocephaly, and fused skull suture. Included campaigns had patients in the U.S. fundraising for craniosynostosis surgery or related expenses. Excluded campaigns were duplicates, for animals, helmets, charities, or other surgeries. Successful campaigns achieved third quartile of …

Seasonal Activity Pattern Of Ambrosia Beetles In Southeast Virginia, Umme H. Akter, Sajrim Chowdhury, Deborah A. Waller

Knowledge and Creativity Expo

Ambrosia beetles (Curculionidae: Scolytinae) are wood-boring insects that influence forest ecosystems through fungal symbioses, rapid host colonization, and invasive species dynamics. Despite their ecological importance, seasonal activity patterns remain poorly characterized in southeastern Virginia. This study integrates field trapping and statistical modeling to examine species-specific seasonal activity across two forested sites in Norfolk, Virginia. Beetles were monitored using ethanol and essential oil-baited bottle traps alongside ethanol-soaked bolt traps. Overall abundance peaked in April, indicating strong early-season emergence. Ethanol-baited traps captured 3-7 times more beetles than essential oil traps, and negative binomial generalized linear models confirmed bait type as a significant …

Methods Of Inducing Cellular Senescence In Lung Fibroblasts, Sara Palega, Jennifer Q. Zhou, Shan Zhu, Yan Y. Sanders

Knowledge and Creativity Expo

Methods of Inducing Cellular Senescence in Lung Fibroblasts

Sara Palega¹, Jennifer Q Zhou², Shan Zhu², Yan Y Sanders²

¹VHS Biomedical Sciences PhD program, ²Department of Biomedical and Translational Sciences, Macon & Joan Brock Virginia Health Sciences at Old Dominion University (ODU)

Introduction: Idiopathic Pulmonary Fibrosis (IPF) is the most prevalent and severe of interstitial lung diseases. This chronic and progressive condition lacks treatment options and is ultimately fatal without a lung transplant. IPF arises from aberrant wound healing that leads to excessive collagen deposition, inflammation, and cystic alveolar growths which makes …

Touching Lives With Empathy And Assurance In Medicine (Team): An Experiential Palliative Care Medicine Program For Medical Students, Kevin A. Barnes, Simone K. Schumaecker, Madeline L. Dunstan, Marissa C. Galicia-Castillo

Knowledge and Creativity Expo

Palliative Care Medicine (PCM) education presents unique challenges as core competencies like communication, response to grief, and engaging seriously ill patients are difficult to teach through classroom instruction. Despite didactics and modules, many medical students report feeling underprepared for end-of-life discussions. Emerging evidence suggests that experiential learning, particularly one-on-one interactions with patients, reduces learner insecurity and deepens understanding of serious illness. The Touching Lives with Empathy and Assurance in Medicine (TEAM) program at Lake Taylor Transitional Care Hospital was developed to address this gap through a structured, longitudinal PCM experience. This project analyzes the program’s design, implementation, and early participation …

Impacts Of Biochar And Fe/Zn-Doped Biochar On The Degradation And Transformation Of Pfas In Wastewater Biosolids Compost, Chase Fry, R. Ryan Dupont, Joan Mclean

Spring Runoff Conference

Background

• >5.8 million dry metric tons of biosolids were produced in 2018.
• It is difficult & expensive to landfill all biosolids produced.
• Biosolids are increasingly used as an agricultural fertilizer and soil amendment.

Living Shorelines As A Solution To Saltwater Marsh Erosion, Elizjah Eddy, Richard Hale

Knowledge and Creativity Expo

In recent years, saltwater marshes fringing the Lafayette River, a tributary of the Elizabeth River, have experienced degradation in response to increased inundation and ocean energy . These marshes provide critical ecological and economic benefits to the City of Norfolk, and prioritizing their long term health and sustainability is an important challenge. An emerging restoration tactic involves enhancing marsh elevation through the application of dredge material that would otherwise require disposal offshore (known as thin-layer placement or TLP). An important first step in TLP projects is characterizing the textural and geochemical properties of the existing marsh sediment. The goal of …

Concomitant Subacromial Decompression Remains Commonly Performed During Rotator Cuff Repair: A Trinetx Study, Madison Baldauf, Zachary Krumm, Savannah Ward, Katherine Worcester, Kevin Bonner Md

Knowledge and Creativity Expo

Introduction:

Arthroscopic rotator cuff repair (RCR) is among the most frequently performed shoulder procedures in the US and is often accompanied by concomitant subacromial decompression (SAD). In recent years some studies have called into question the benefit of SAD in this setting. The topic is controversial as many surgeons still feel SAD is indicated. This study aims to characterize the changes in proportion of SAD performed concomitantly with RCR over recent years using TriNetX.

Methods:

The TriNetX database was queried for all patients undergoing arthroscopic rotator cuff repair from 2013 to 2025. Cohorts were established using the Current Procedural Terminology …