Digital Commons Network^™

Metabolite Profiling Of Premium Civet Luwak Bio-Transformed Coffee Compared With Conventional Coffee Types, As Analyzed Using Chemometric Tools, Mohamed A. Farag, Tarik A. Mohamed, Enas A. El-Hawary, Amr Abdelwareth

Faculty Journal Articles

No abstract provided.

2023-01-24_Michiganoverview_Isdreporting, Michigan Department Of Health & Human Services

Michigan COVID-19 Outbreak Reports

The K-12 Aged ISD Reporting page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/stats/k-to-12-aged-isd-reporting.

This report is created from data reported by the Michigan Disease Surveillance System (MDSS) the Michigan Department of Health and Human Services' web-based communicable disease reporting system. Data is updated every week.

The purpose of the dashboard is to report the 7 day average of COVID-19 cases in Michigan school students aged 5 through 18 at the intermediate school district and school district levels, as well as display trends over time to better illustrate the changing nature of the COVID-19 pandemic. Cases are attributed to …

2023-01-24_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus/stats.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled. COVID case and testing data will be posted once a week on Tuesdays.

This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time polymerase chain reaction (NAAT/RT-PCR) …

The Indiana Statesman, January 24, 2023, Indiana State University

Student Newspaper

Roxane Gay to be next speaker in Speaker Series; Karaoke: Sycamores sang their hearts out last week in the HMSU; Police investigate single-car crash; How a man disarmed the Monterey Park shooter

The Influence Of Relational Aggression And Attachment Insecurity On Sexual Dissatisfaction: Using The Actor-Partner Interdependence Mediation Model, Min Xu Phd Lmft, Lee N. Johnson, Sarah M. Coyne

School of Leadership and Education Sciences: Faculty Scholarship

The majority of studies on couple aggressive behaviors have focused on more overt forms (e.g., intimate partner violence), while findings on covert patterns of aggression are lacking. This study aims to explore the direct and indirect effects of two types of relational aggression (i.e., love withdrawal and social sabotage) on sexual dissatisfaction, with attachment anxiety and attachment avoidance as the mediators. Participants were 324 married couples from a large northwestern city in the United States. Direct actor effects from love withdrawal were found for both partners, while direct actor effects from social sabotage were only found for husbands. Direct partner …

Tmem161b Modulates Radial Glial Scaffolding In Neocortical Development., Lu Wang, Caleb Heffner, Keng Ioi Vong, Chelsea Barrows, Yoo-Jin Ha, Sangmoon Lee, Pablo Lara-Gonzalez, Ishani Jhamb, Dennis Van Der Meer, Robert Loughnan, Nadine Parker, David Sievert, Swapnil Mittal, Mahmoud Y Issa, Ole A Andreassen, Anders Dale, William B Dobyns, Maha S Zaki, Stephen A Murray, Joseph G Gleeson

Faculty Research 2023

TMEM161B encodes an evolutionarily conserved widely expressed novel 8-pass trans- membrane protein of unknown function in human. Here we identify TMEM161B homozygous hypomorphic missense variants in our recessive polymicrogyria (PMG) cohort. Patients carrying TMEM161B mutations exhibit striking neocortical PMG and intellectual disability. Tmem161b knockout mice fail to develop midline hem- ispheric cleavage, whereas knock-in of patient mutations and patient-derived brain organoids show defects in apical cell polarity and radial glial scaffolding. We found that TMEM161B modulates actin filopodia, functioning upstream of the Rho-GTPase CDC42. Our data link TMEM161B with human PMG, likely regulating radial glia apical polarity during neocortical development.

United States For The Use V. New Age Development Group Llc

2023 Decisions

USDC for the Eastern District of Pennsylvania

2023-01-24_Michiganoverview_Covidlongtermcare, Michigan Department Of Health & Human Services

Michigan COVID-19 Long Term Care Data

The COVID Long Term Care Facilities page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/stats/data-about-places/long-term-care-data.

This report is created by the Michigan Department of Health & Human Services from data self-reported by long-term care facilities into EMResource. Data for all reporting facilities is posted weekly each Monday.

The information below represents COVID-19 data reported directly to MDHHS by licensed and operating Skilled Nursing, Home for the Aged and Adult Foster Care facilities (licensed to serve 13 or more individuals) in Michigan from January 1, 2020. All long-term care facilities additionally have an obligation to report COVID-positive residents and/or staff …

Minutes 1-24-2023 | Budget Committee, Expenditure Subcommittee, Megan Phillips

Budget Committee Minutes

No abstract provided.

Coupling Nitrate Capture With Ammonia Production Through Bifunctional Redox-Electrodes, Kwiyong Kim, Alexandra Zagalskaya, Jing Lian Ng, Jaeyoung Hong, Vitaly Alexandrov, Tuan Anh Pham, Xiao Su

Department of Chemical and Biomolecular Engineering: Faculty Publications

Nitrate is a ubiquitous aqueous pollutant from agricultural and industrial activities. At the same time, conversion of nitrate to ammonia provides an attractive solution for the coupled environmental and energy challenge underlying the nitrogen cycle, by valorizing a pollutant to a carbon-free energy carrier and essential chemical feedstock. Mass transport limitations are a key obstacle to the efficient conversion of nitrate to ammonia from water streams, due to the dilute concentration of nitrate. Here, we develop bifunctional electrodes that couple a nitrate-selective redox-electrosorbent (polyaniline) with an electrocatalyst (cobalt oxide) for nitrate to ammonium conversion. We demonstrate the synergistic reactive separation …

Mapping The Opal Score For Clinical Trials To Coordinator Hours: A Single Site Study, Kesley Tyson

MUSC Theses and Dissertations

Workload assessments help provide validation to increase staff, evaluate and ensure equal distribution of work, and assist with budget justifications. The Ontario Protocol Assessment Level (OPAL) is one of the most widely used protocol assessment tools. This study mapped an adapted OPAL score for clinical trials to actual coordinator hours from a single site to determine if the adapted OPAL score could predict coordinator hours. The purpose was to project a more accurate capacity estimate when considering new studies. The Morehouse School of Medicine (MSM) clinical trials management system was queried for actively enrolling interventional studies with corresponding coordinator effort …

January 24, 2023, Faculty Senate

Minutes

No abstract provided.

2023-01-24_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus/stats/coronavirus-symptoms. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated twice a week on Mondays and Thursdays.

Syndromic Surveillance System data is obtained from approximately 216 facilities participating in syndromic surveillance (139 Emergency Departments (ED), 77 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, …

2023-01-24_Michiganoverview_Covidcounts, Michigan Department Of Health & Human Services

Michigan COVID-19 Confirmed Cases by Date of Onset Data

Data was downloaded as an Excel spreadsheet which appeared in the Public Use Datasets section under the Cumulative Data link of Michigan's Coronavirus webpage, under the url https://www.michigan.gov/coronavirus/stats.

Cases are aggregated by the date of onset of COVID-19 symptoms, if known, otherwise by laboratory specimen date if known, otherwise by case referral date. Deaths are aggregated by the date of death if known, otherwise by the last date of a change to the case status.

Evaluation Of Pollination Traits Important For Hybrid Wheat Development In Great Plains Germplasm, Nicholas Garst, Vikas Belamkar, Amanda Easterly, Mary J. Guttieri, Hannah Stoll, Amir M. H. Ibrahim, P. Stephen Baenziger

Department of Agronomy and Horticulture: Faculty Publications

Hybrid wheat (Triticum aestivumL.) offers potential yield advantages over conventional inbred cultivars. For hybrid wheat to be a commercial success, the cost to produce the hybrid seed needs to be minimized. Although wheat is naturally selfpollinated, hybrid wheat seed production can be improved by increasing the amount and availability of pollen for cross-pollination. This research examined 19 pollination traits using the Hard Winter Wheat Association Mapping Panel for 3 years. Anther extrusion, pollen 50 date (date at which a genotype has 50% of spikes pollinating), plant height, and pollination duration (last spike pollen 50 date minus first spike …

Ancient Pathogens Provide A Window Into Health And Well-Being, Cecil M. Lewis Jr., Mercy Y. Akinyi, Sharon Dewitte, Anne C. Stone

Faculty Publications

This perspective draws on the record of ancient pathogen genomes and microbiomes illuminating patterns of infectious disease over the course of the Holocene in order to address the following question. How did major changes in living circumstances involving the transition to and intensification of farming alter pathogens and their distributions? Answers to this question via ancient DNA research provide a rapidly expanding picture of pathogen evolution and in concert with archaeological and historical data, give a temporal and behavioral context for heath in the past that is relevant for challenges facing the world today, including the rise of novel pathogens.

Student Affairs Minutes 01/24/2023, Student Affairs Committee

Student Affairs Committee

No abstract provided.

Reframing Occupational Stress To Mitigate Burnout: A Trauma-Informed Care And Constructive Living Approach To Foster Lifelong Resiliency And Self-Directed Life Management Within Academic Libraries, Wendy C. Doucette, Rebecca Tolley

ETSU Faculty Works

This editorial chapter addresses the problem of burnout in academic libraries by introducing a fusion of principles from trauma-informed care (TIC) and Constructive Living (CL) to offer unique, easy-to-incorporate plans of action to identify and mitigate symptoms of burnout. These two action-based philosophies, which may be new to most readers, provide strategies for considering, practicing, and adopting perspectives and behaviors that may give those suffering from burnout new ways of thinking about their professional and personal lives. We identify accessible opportunities to connect mind and body in self-care to neutralize negative self-talk, regain perspective and balance, and foster lifelong resiliency …

The Human Gut Microbiome, Tammy J. Ladue

InterProfessional Education Research and Scholarship

Although the gut microbiome has been known for many years, it wasn’t until the mid-1970’s that a relationship was hypothesized in medical journals. With the advent of the Human Genome Project in 2001 (Adak & Khan, 2019) further investigation into the types and relationship of the microbes in the GI tract were seriously studied.

Utilizing DNA & RNA tracking and culture techniques found during the Genome Project, more information was found on the Gut Microbiome. It was as of 2017 that the knowledge on the Microbiome began to show promise. It has been speculated that the GI tract has approximately …

January 24, 2023 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Covid-19 Vaccination Up-Take In Three Districts Of Nepal, Tara Nath Pokhrel, Kshitij Karki, Bhim Singh Tinkari, Shyam Raj Upreti, Shikha Upadhyaya Khatiwada, Rakchya Amatya, John Zervos, Linda M. Kaljee, Kate Zenlea, Tyler Prentiss, Gina Maki, Anita B. Shallal, Seema Joshi, Marcus J. Zervos, Katie Latack, Bidushi Pokhrel, Alina Upreti, Bibek Kumar Lal, Sagar Dahal, Jhalak Sharma Gautam, Dipendra Raman Singh, Deepak C. Bajracharya

Infectious Diseases Articles

Vaccine hesitancy during the COVID-19 pandemic continues to be an issue in terms of global efforts to decrease transmission rates. Despite high demand for the vaccines in Nepal, the country still contends with challenges related to vaccine accessibility, equitable vaccine distribution, and vaccine hesitancy. Study objectives were to identify: 1) up-take and intention for use of COVID-19 vaccines, 2) factors associated with vaccine up-take, and 3) trusted communication strategies about COVID-19 and the vaccines. A quantitative survey was implemented in August and September 2021 through an initiative at the Nepali Ministry of Health and Population Department of Health Services, Family …

The End Of The “Chemical Imbalance” Theory Of Depression - What Now?, Austin Brown

Population Health Research Brief Series

For decades, those diagnosed with depression have been told they suffer from a “chemical imbalance.” This explanation involves neurotransmitters, such as serotonin, thought to be the main neurochemical responsible for major depressive disorders. Growing research challenges this theory and the need for medication therapies for depressive symptoms. This brief summarizes new findings examining the theory that depression is caused by a chemical imbalance and calls for healthcare professionals and patients to consider the market influences and social structures that impact health.

Global Investments In Pandemic Preparedness And Covid-19: Development Assistance And Domestic Spending On Health Between 1990 And 2026, Angela E. Micah, Kayleigh Bhangdia, Ian E. Cogswell, Dylan Lasher, Brendan Lidral-Porter, Ismaeel Yunusa Ph. D., Et Al.

Faculty Publications

Background The COVID-19 pandemic highlighted gaps in health surveillance systems, disease prevention, and treatment globally. Among the many factors that might have led to these gaps is the issue of the financing of national health systems, especially in low-income and middle-income countries (LMICs), as well as a robust global system for pandemic preparedness. We aimed to provide a comparative assessment of global health spending at the onset of the pandemic; characterise the amount of development assistance for pandemic preparedness and response disbursed in the first 2 years of the COVID-19 pandemic; and examine expectations for future health spending and put …

Born To Care (Or Not): How Gender Role Attitudes Affect Occupational Sorting, Carlianne Patrick, Heather Stephens, Amanda Weinstein

Regional Research Institute Working Papers

Occupation segregation explains a significant portion of the gender wage gap, with women working in lower paid female-dominated occupations. We examine how childhood and adolescent exposure to gender biased norms about work influence this occupational sorting. We document that early life exposure to traditional gender role attitudes, which view women’s role as caretakers, increase women’s likelihood of employment in care occupations and decrease the likelihood for men, thereby increasing the gender care occupation gap. A decomposition of the factors affecting this sorting shows that a primary channel is through differences in the choice of post-secondary field of study or major. …

Silver Nanoparticle Surface Chemistry Determines Interactions With Human Serum Albumin And Cytotoxic Responses In Human Liver Cells, Kira M. Fahy, Madeline K. Eiken, Karl V. Baumgartner, Kaitlyn Q. Leung, Sarah E. Anderson, Erik Berggren, Evangelia Bouzos, Lauren R. Schmitt, Prashanth Asuri, Korin E. Wheeler

Chemistry and Biochemistry

Engineered nanomaterials (ENMs) are synthesized with a diversity of surface chemistries that mediate biochemical interactions and physiological response to the particles. In this work, silver engineered nanomaterials (AgENMs) are used to evaluate the role of surface charge in protein interactions and cellular cytotoxicity. The most abundant protein in blood, human serum albumin (HSA), was interacted with 40 nm AgENMs with a range of surface-charged coatings: positively charged branched polyethyleneimine (bPEI), negatively charged citrate (CIT), and circumneutral poly(ethylene glycol) (PEG). HSA adsorption to AgENMs was monitored by UV–vis spectroscopy and dynamic light scattering, while changes to the protein structure were evaluated …

Narrowing The Gap Between Research And Policy: Using Rapid Evaluation During The Covid-19 Crisis, K Anil

School of Health Professions

An evidence base is vital to ensure well-informed policies with systematic processes.1,2 However, A research-to-policy gap exists that is widened by the discrepancy between the extensive time it takes to conduct conventional academic research and the short timescale over which policy-makers are often required to make decisions.2 This is especially concerning in times of crisis, such as the COVID-19 pandemic, that demanded an avalanche of data, analysis, and interpretation to be provided over a very short period of time. Rapid evaluation can be used to generate research-based evidence under pressure to inform decision-making and policy. Existing literature clearly details the …

Academic Senate - Minutes, 1/24/2023, Academic Senate

Academic Senate Minutes

No abstract provided.

Landscape And Site Factors Drive Invasive Phragmites Management And Native Plant Recovery Across Chesapeake Bay Wetlands, Christine B. Rohal, Eric L. G. Hazelton, Eliza K. Mcfarland, Rebekah Downard, Melissa K. Mccormick, Dennis F. Whigham, Karin M. Kettenring

Watershed Sciences Student Research

Successful invasive plant management—where invaders are sufficiently reduced and diverse native plant communities recover—remains an elusive goal for land managers. The site- and landscape-scale drivers of variable management outcomes and vegetation recovery are poorly understood due to a lack of rigorous experiments that characterize longer term vegetation trends across contexts. We present the results of a five-year experiment across eight subestuaries of Chesapeake Bay, representing a gradient of watersheds with differing dominant land-use types and anthropogenic impacts, to evaluate invasive and native plant response to herbicide management. The focal invader, Phragmites australis (common reed), is one of the most aggressive …

Annual Comprehensive Financial Report, Hamilton County, Tennessee For The Year Ended June 30, 2022, Hamilton County (Tenn.). Finance Division.

Tennessee County Audit Reports

No abstract provided.

Recent Advances In Understanding Of Pathogenesis Of Alcohol-Associated Liver Disease, Xiaoqin Wu, Xiude Fan, Tatsunori Miyata, Adam Kim, Christina K Cajigas-Du Ross, Semanti Ray, Emily Huang, Moyinoluwa Taiwo, Rakesh Arya, Jianguo Wu, Laura E Nagy

Faculty, Staff and Student Publications

Alcohol-associated liver disease (ALD) is one of the major diseases arising from chronic alcohol consumption and is one of the most common causes of liver-related morbidity and mortality. ALD includes asymptomatic liver steatosis, fibrosis, cirrhosis, and alcohol-associated hepatitis and its complications. The progression of ALD involves complex cell-cell and organ-organ interactions. We focus on the impact of alcohol on dysregulation of homeostatic mechanisms and regulation of injury and repair in the liver. In particular, we discuss recent advances in understanding the disruption of balance between programmed cell death and prosurvival pathways, such as autophagy and membrane trafficking, in the pathogenesis …