Digital Commons Network^™

Faculty Senate Chronicle February 2, 2023, Heather M. Loughney

The University of Akron Faculty Senate Chronicle

Minutes for the regular meeting of The University of Akron Faculty Senate on February 2, 2023

Montana Kaimin, February 2, 2023, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

February 2, 2023, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Landsbankinn Hf. Consolidated Financial Statements 2022, Landsbankinn Hf

Documents

No abstract provided.

Alaska Earthquake Center Quarterly Technical Report October-December 2022, Natalia Ruppert

Alaska Earthquake Center Reports

This series of technical quarterly reports from the Alaska Earthquake Center (AEC) includes detailed summaries and updates on Alaska seismicity, the AEC seismic network and stations, field work, our social media presence, and lists publications and presentations by AEC staff. Multiple AEC staff members contribute to this report. It is issued in the following month after the completion of each quarter Q1: January-March, Q2: April-June, Q3: July-September, and Q4: October-December. The first report was published for January-March, 2021.

Time Is Brain: How A Descriptive Analysis Of Telestroke Metrics Can Improve Program Performance, Christopher Cordero

MUSC Theses and Dissertations

In the event of an acute ischemic stroke, 1.9 million neurons are lost in the brain per minute. Since the inception of thrombolytic therapy and mechanical thrombectomy as effective tools in the treatment of acute ischemic stroke, the focal point of quality improvement in this field has become the time to treatment delivery. As rural and more interspersed environments exhibit high disability and mortality rates associated with these acute neurological conditions, inequities in timely care delivered to these patient populations persist. Limitations in access are now abated by the extension of neurologist expertise into these areas via Telestroke. This study …

February 2023 Faculty Senate Packet, University Of Nebraska At Kearney Faculty Senate

Faculty Senate Packets

No abstract provided.

One-Stage Synovectomies Result In Improved Short-Term Outcomes Compared To Two-Stage Synovectomies Of Diffuse-Type Tenosynovial Giant Cell Tumor (D-Tgct) Of The Knee: A Multicenter, Retrospective, Cohort Study, Geert Spierenburg, Floortje G M Verspoor, Jay S Wunder, Anthony M Griffin, Peter C Ferguson, Matthew T Houdek, David M King, Richard Boyle, Robert Lor Randall, Steven W Thorpe, Jacob I Priester, Erik J Geiger, Lizz Van Der Heijden, Nicholas M Bernthal, Bart H W B Schreuder, Hans Gelderblom, Michiel A J Van De Sande

Rothman Institute Papers

Diffuse-type tenosynovial giant cell tumors' (D-TGCTs) intra- and extra-articular expansion about the knee often necessitates an anterior and posterior surgical approach to facilitate an extensive synovectomy. There is no consensus on whether two-sided synovectomies should be performed in one or two stages. This retrospective study included 191 D-TGCT patients from nine sarcoma centers worldwide to compare the postoperative short-term outcomes between both treatments. Secondary outcomes were rates of radiological progression and subsequent treatments. Between 2000 and 2020, 117 patients underwent one-stage and 74 patients underwent two-stage synovectomies. The maximum range of motion achieved within one year postoperatively was similar (flexion …

Preparing And Complying With The New And Upcoming Nih (National Institute Of Health) Data Management And Sharing (Dms) Policy- What To Know, Marlowe A. Bogino, Benjamin H. Saracco

Library Workshops

Learning objectives:

Understand what the purpose and aspects of the NIH (National Institutes of Health) data policy are Learn key elements provided within the NIH policy. Learn about tools and Resources to assist with how to prepare and submit a data management plan to NIH. Learn what resources and Rowan libraries resource/ services that are available to assist with data management.

The 2003 NIH Data Sharing Policy has been revised, and the new policy goes into effect on January 25, 2023. In January 2023, the US National Institutes of Health (NIH) will begin requiring researchers who obtain funds from them …

Reducing Stigma Associated With Opioid Use Disorder Through Narrative: Crystal's Story, Melanie Gordon, Crystal Pfingston

Advocate GME

No abstract provided.

Insights Into Cell-Specific Functions Of Microtubules In Skeletal Muscle Development And Homeostasis, Lathan Lucas, Thomas A Cooper

Faculty, Staff and Students Publications

The contractile cells of skeletal muscles, called myofibers, are elongated multinucleated syncytia formed and maintained by the fusion of proliferative myoblasts. Human myofibers can be hundreds of microns in diameter and millimeters in length. Myofibers are non-mitotic, obviating the need for microtubules in cell division. However, microtubules have been adapted to the unique needs of these cells and are critical for myofiber development and function. Microtubules in mature myofibers are highly dynamic, and studies in several experimental systems have demonstrated the requirements for microtubules in the unique features of muscle biology including myoblast fusion, peripheral localization of nuclei, assembly of …

A Dlg1-Arhgap31-Cdc42 Axis Is Essential For The Intestinal Stem Cell Response To Fluctuating Niche Wnt Signaling, David Castillo-Azofeifa, Tomas Wald, Efren A Reyes, Aaron Gallagher, Julia Schanin, Stephanie Vlachos, Nathalie Lamarche-Vane, Carolyn Bomidi, Sarah Blutt, Mary K Estes, Todd Nystul, Ophir D Klein

Faculty, Staff and Students Publications

A central factor in the maintenance of tissue integrity is the response of stem cells to variations in the levels of niche signals. In the gut, intestinal stem cells (ISCs) depend on Wnt ligands for self-renewal and proliferation. Transient increases in Wnt signaling promote regeneration after injury or in inflammatory bowel diseases, whereas constitutive activation of this pathway leads to colorectal cancer. Here, we report that Discs large 1 (Dlg1), although dispensable for polarity and cellular turnover during intestinal homeostasis, is required for ISC survival in the context of increased Wnt signaling. RNA sequencing (RNA-seq) and genetic mouse models demonstrated …

Safety Behind The Computer Screen: Gauging Public Perceptions About Teacher Student Sexual Abuse, Kilby E. Raptopoulos

Theses and Dissertations

Female sex offenders are often portrayed in the media more leniently than male sex offenders, which could influence the way the public perceives these offenders. Further, the media is not always accurate in how they portray sex crimes either which can translate to misconceptions among the public specifically regarding sex offenders. The purpose of this research was to explore media coverage of teacher student sexual abuse in relation to the public’s reaction to these news stories. The current study utilized news stories to analyze reader comments on a news website to understand 1) how teacher sex offenders are portrayed, 2) …

U.S. Department Of The Interior: Sharing Fair Data Fairly, Jason Earl Duke

Theses and Dissertations

Thousands of scientists, researchers, students, and organizations consume government-produced data daily that are often difficult to locate because they are collected and stored in multiples at varying levels of quality, inhibiting their usefulness for data science investigations and analysis. To address these challenges, United States Government agencies and bureaus have been implementing Findable, Accessible, Interoperable, and Reusable (FAIR) Data Principles into their data-sharing strategies since 2016. However, differing interpretations of the FAIR Data Principles lead to data that must be documented uniformly and adequately integrated for reuse. Select datasets have been analyzed with peer-reviewed FAIR assessment tools to establish a …

Presence Of Symptoms 6 Weeks After Covid-19 Among Vaccinated And Unvaccinated Us Healthcare Personnel: A Prospective Cohort Study, Nicholas M. Mohr, Ian D. Plumb, Kari K. Harland, Tamara Pilishvili, Katherine E. Fleming-Dutra, Anusha Krishnadasan, Karin F. Hoth, Sharon H. Saydah, Zachary Mankoff, John P. Haran, Melissa Briggs-Hagen, Eliezer Santos León, David A. Talan

Department of Emergency Medicine Faculty Papers

OBJECTIVES: Although COVID-19 vaccines offer protection against infection and severe disease, there is limited information on the effect of vaccination on prolonged symptoms following COVID-19. Our objective was to determine differences in prevalence of prolonged symptoms 6 weeks after onset of COVID-19 among healthcare personnel (HCP) by vaccination status, and to assess differences in timing of return to work.

DESIGN: Cohort analysis of HCP with COVID-19 enrolled in a multicentre vaccine effectiveness study. HCP with COVID-19 between December 2020 and August 2021 were followed up 6 weeks after illness onset.

SETTING: Health systems in 12 US states.

PARTICIPANTS: HCP participating …

Deciphering Microbiota Of Acute Upper Respiratory Infections: A Comparative Analysis Of Pcr And Mngs Methods For Lower Respiratory Trafficking Potential, Sadia Almas, Rob E. Carpenter, Anuradha Singh, Chase Rowan, Vaibhav Tamrakar, Rahul Sharma

Human Resource Development Faculty Publications and Presentations

Although it is clinically important for acute respiratory tract (co)infections to have a rapid and accurate diagnosis, it is critical that respiratory medicine understands the advantages of current laboratory methods. In this study, we tested nasopharyngeal samples (n = 29) with a commercially available PCR assay and compared the results with those of a hybridization-capture-based mNGS workflow. Detection criteria for positive PCR samples was Ct < 35 and for mNGS samples it was >40% target coverage, median depth of 1X and RPKM > 10. A high degree of concordance (98.33% PPA and 100% NPA) was recorded. However, mNGS yielded positively 29 additional microorganisms (23 bacteria, 4 viruses, and …

Systems Thinking Activities Used In K-12 For Up To Two Decades, Diana Fisher, Systems Thinking Association

Complex Systems Faculty Publications and Presentations

Infusing systems thinking activities in pre-college education (grades K-12) means updating precollege education so it includes a study of many systemic behavior patterns that are ubiquitous in the real world. Systems thinking tools include those using both paper and pencil and the computer and enhance learning in the classroom making it more student-centered, more active, and allowing students to analyze problems that have been heretofore beyond the scope of K-12 classrooms. Students in primary school have used behavior over time graphs to demonstrate dynamics described in story books, like the Lorax, and created stock-flow diagrams to describe what was needed …

Fetal Demise And Wernicke–Korsakoff Syndrome In A Patient With Hyperemesis Gravidarum: A Case Report, Alisa Olmsted, Andrea Desimone, Jahaira Lopez-Pastrana, Madeleine Becker

Department of Psychiatry and Human Behavior Faculty Papers

Background: Wernicke–Korsakoff syndrome is a neuropsychiatric disorder caused by thiamine deficiency composed of two related disorders accounting for an acute presentation and chronic progression. Hyperemesis gravidarum presents a significant risk factor for Wernicke–Korsakoff syndrome as symptoms may rapidly progress in the setting of pregnancy. We present the first-reported case of hyperemesis-gravidarum-associated Wernicke encephalopathy in a patient in the first half of pregnancy in which a missed diagnosis led to septic shock, fetal demise, and eventual profound Korsakoff syndrome.

Case Presentation: We present the case of a 33-year-old primigravid African American woman at 15 weeks gestational age who initially presented at …

Comprehensive Smn1 And Smn2 Profiling For Spinal Muscular Atrophy Analysis Using Long-Read Pacbio Hifi Sequencing., Xiao Chen, John Harting, Emily G. Farrow, Isabelle Thiffault, Dalia Kasperaviciute, Genomics England Research Consortium, Alexander Hoischen, Christian Gilissen, T Pastinen, Michael A. Eberle

Manuscripts, Articles, Book Chapters and Other Papers

Spinal muscular atrophy, a leading cause of early infant death, is caused by bi-allelic mutations of SMN1. Sequence analysis of SMN1 is challenging due to high sequence similarity with its paralog SMN2. Both genes have variable copy numbers across populations. Furthermore, without pedigree information, it is currently not possible to identify silent carriers (2+0) with two copies of SMN1 on one chromosome and zero copies on the other. We developed Paraphase, an informatics method that identifies full-length SMN1 and SMN2 haplotypes, determines the gene copy numbers, and calls phased variants using long-read PacBio HiFi data. The SMN1 and SMN2 copy-number …

Clemson Board Of Trustee Minutes, Full Board Minutes, 2023 Februrary 2, Clemson University Board Of Trustees

Minutes

No abstract provided.

Clemson Board Of Trustee Minutes, Educational Policy Committee, 2023 Februrary 2, Clemson University Board Of Trustees

Minutes

No abstract provided.

Considering Community Partnerships And New Projects: Advice From The Field, Morgan Rose Pershing

Faculty Research, Scholarly, and Creative Activity

There are many considerations to take before embarking on a new project or creating a new community partnership. Many such considerations are undocumented and not widely taught in Master of Library and Information Science programs. This article fills in the gap with suggested steps to take before implementing a new service or partnership. Recommendations stem from the author’s own experiences and aim to help public library workers—from staff to administration—avoid possible pitfalls and become effective advocates for focus and intentionality.

Dave Barsky, Oral History Interview, 2023, Katherine Hacanyan

Oral Histories

In the Fall of 2022, Matt Jones’s Oral History Techniques class conducted a set of interviews documenting the stories behind the student unrest on Eastern Michigan University’s campus from 1966-1972. Dave Barsky was a student at EMU in the late 1960s and early 1970s. He was a dedicated student activist, and worked closely with others like Frank Michels on the Second Coming. Barsky was represented by the American Civil Liberties Union after getting expelled from EMU, and continued to be an activist leader.

Association Between P2y12 Inhibitor Reloading And In-Hospital Outcomes For Patients With Non-St-Segment Elevation Acute Coronary Syndrome Already On Chronic P2y12 Receptor Inhibitors Therapy In China: Findings From The Ccc-Acs (Improving Care For Cardiovascular Disease In China-Acute Coronary Syndrome) Project, Yintang Wang, Yu Geng, Ou Zhang, Qin Xu, Yajun Xue, Boda Zhou, Ping Zhang

Faculty, Staff and Student Publications

BACKGROUND: The association between P2Y12 receptor inhibitors reloading and in-hospital outcomes in non-ST-segment elevation acute coronary syndrome (NSTEACS) patients who were on chronic P2Y12 receptor inhibitors therapy remained underdetermined.

METHODS: The Improving Care for Cardiovascular Disease in China-Acute Coronary Syndrome (CCC-ACS project) is a national registry active from November 2014 to December 2019. 4790 NSTEACS patients on chronic P2Y12 receptor inhibitors therapy were included. Cox proportional hazard models, Kaplan-Meier curves, and subgroup analyses were conducted.

RESULTS: The NSTEACS patients who received reloading of P2Y12 receptor inhibitors were younger and had fewer comorbid conditions. The reloading group had a lower risk …

Matrix-Entrapped Fibers Create Ecological Niches For Gut Bacterial Growth, Nuseybe Bulut, Thaisa M. Cantu-Jungles, Xiaowei Zhang, Zeynep Mutlu, Mukerrem Cakmak, Bruce R. Hamaker

Purdue University Libraries Open Access Publishing Fund

Insoluble plant cell walls are a main source of dietary fiber. Both chemical and physical fiber structures create distinct niches for gut bacterial utilization. Here, we have taken key fermentable solubilized polysaccharides of plant cell walls and fabricated them back into cell wall-like film forms to understand how fiber physical structure directs gut bacterial fermentation outcomes. Solubilized corn bran arabinoxylan (Cax), extracted to retain some ferulate residues, was covalently linked using laccase to form an insoluble cell wall-like film (Cax-F) that was further embedded with pectin (CaxP-F). In vitro fecal fermentation using gut microbiota from three donors was performed on …

Measuring Religiosity Of East Asians: Multiple Religious Belonging, Believing, And Practicing, Fenggang Yang, Brian Mcphail

Department of Sociology Faculty Publications

Social surveys normally assume that respondents adhere to a single religious faith in belonging, believing, and practicing congruently. Some surveys even take religious identity as the singular measure of religiosity and examine its relationship with other variables. This practice, however, fails to capture nonexclusive and hybrid religiosity, which is arguably the traditional and normal pattern in East Asia while becoming increasingly common in the West. We have developed a new set of survey questions and conducted a survey among East Asian international students at an American university. The findings show that multiple religious belonging, believing, and practicing are quite common, …

Interactions Between Humans And Dogs During The Covid-19 Pandemic: Recent Updates And Future Perspectives, Mohamed S. Kamel, Amr A. El-Sayed, Rachel A. Munds, Mohit S. Verma

Purdue University Libraries Open Access Publishing Fund

COVID-19 is one of the deadliest epidemics. This pandemic is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but the role of dogs in spreading the disease in human society is poorly understood. This review sheds light on the limited susceptibility of dogs to COVID-19 infections which is likely attributed to the relatively low levels of angiotensin-converting enzyme 2 (ACE2) in the respiratory tract and the phylogenetic distance of ACE2 in dogs from the human ACE2 receptor. The low levels of ACE2 affect the binding affinity between spike and ACE2 proteins resulting in it being uncommon for dogs to …

The Waxy Mutation In Sorghum And Other Cereal Grains Reshapes The Gut Microbiome By Reducing Levels Of Multiple Beneficial Species, Qinnan Yang, Mallory J. Suhr Van Haute, Scott E. Sattler, Devin J. Rose, Anthony Juritsch, Jing Shao, Kristin A. Beede, Robert J. Schmaltz, Jeff Price, John Toy, Amanda E. Ramer-Tait, Andrew K. Benson

Department of Food Science and Technology: Faculty Publications

Waxy starches from cereal grains contain >90% amylopectin due to naturally occurring mutations that block amylose biosynthesis. Waxy starches have unique organoleptic characteristics (e.g. sticky rice) as well as desirable physicochemical properties for food processing. Using isogenic pairs of wild type sorghum lines and their waxy derivatives, we studied the effects of waxy starches in the whole grain context on the human gut microbiome. In vitro fermentations with human stool microbiomes show that beneficial taxonomic and metabolic signatures driven by grain from wild type parental lines are lost in fermentations of grain from the waxy derivatives and the beneficial signatures …

Supporting Cardiac Perfusion By Preboa With Reduced Visceral Ischemia Despite Extended Occlusion, Paige Deville, John Hunt, Alan B. Marr, Lance Stuke, Patrick Greiffenstein, Jonathan Schoen, Alison Smith

School of Medicine Faculty Publications

No abstract provided.

Clinical Outcomes With And Without Adherence To Evidence-Based Medicine Guidelines For Lumbar Degenerative Spondylolisthesis Fusion Patients, Glenn A Gonzalez, Guilherme Porto, Kevin Hines, Daniel Franco, Thiago S Montenegro, Aria Mahtabfar, Matthew O'Leary, J. Miao, Sara Thalheimer, Joshua Pelta-Heller, Ashwini Sharan, James Harrop

Department of Neurosurgery Faculty Papers

Introduction: Degenerative lumbar spondylolisthesis (DS) patients are treated with instrumented fusion, following EBM guidelines, and typically have excellent clinical outcomes. However, not all lumbar fusion procedures adhere to EBM guidelines, typically due to a lack of prospective data.

Objective: This retrospective study compared outcomes of DS lumbar fusion patients treated according to EBM guidelines (EBM concordant) to lumbar fused patients with procedures that did not have clear EBM literature that supported this treatment, the goal being to examine the value of present EBM to guide clinical care.

Methods: A total of 125 DS patients were considered EBM concordant, while 21 …