Digital Commons Network^™

Knockout Of Ace-N Facilitates Improved Cardiac Function After Myocardial Infarction, Hamid Suhail, Hongmei Peng, Jiang Xu, Hani N. Sabbah, Khalid Matrougui, Tang-Dong Liao, Pablo A. Ortiz, Kenneth E. Bernstein, Nour-Eddine Rhaleb

Hypertension and Vascular Research Articles

Angiotensin-converting enzyme (ACE) hydrolyzes N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) into inactive fragments through its N-terminal site (ACE-N). We previously showed that Ac-SDKP mediates ACE inhibitors' cardiac effects. Whether increased bioavailability of endogenous Ac-SDKP caused by knocking out ACE-N also improves cardiac function in myocardial infarction (MI)-induced heart failure (HF) is unknown. Wild-type (WT) and ACE-N knockout (ACE-NKO) mice were subjected to MI by ligating the left anterior descending artery and treated with vehicle or Ac-SDKP (1.6 mg/kg/day, s.c.) for 5 weeks, after which echocardiography was performed and left ventricles (LV) were harvested for histology and molecular biology studies. ACE-NKO mice showed increased plasma …

Humor Writer Of The Month: Beth Lapides, Erma Bombeck Writers' Workshop

Erma Bombeck Writers' Workshop Blog

Beth Lapides, a writer, comedian, producer and host best known for creating Uncabaret, is our Humor Writer of the Month for March. Her audio book So You Need to Decide was named one of Vulture's best comedy books of 2022.

Issue 4, Fire & Ice, Joseph Leszczynski

Thrive

No abstract provided.

The Policy Environment Of Self-Care: A Case Study Of The Philippines, Leonardo Jaminola Iii, Jana Marie Negre, Veincent Christian F. Pepito, Arianna Maever Loreche, Manuel M. Dayrit

Ateneo School of Medicine and Public Health Publications

Self-care is the ability and empowerment of individuals to maintain health through informed health-care decisions, with or without the support of a health provider. High-income countries have made advances to their conceptualization, research and institutionalization of self-care, given its reported benefits to patients, the health system and economy. A similar undertaking in low- and middle-income countries (LMICs) with already fragile health systems is warranted as highlighted by the coronavirus disease 2019 pandemic. Our article therefore aimed to describe and analyse the policy environment of self-care using the Philippines as a case study, which may have relevance to other similar countries …

Collaboration And Writing Development In L2 Spanish: A Microanalytic Perspective, Brian Olovson

Dimensions

This case study focuses on how two learners position themselves as partners in a collaborative writing activity in a Spanish Writing course. I utilize a micro-discourse analytic approach (Eskildsen & Markee, 2018; van Compernolle, 2015, 2018) to highlight the situated nature of collaboration and the dynamicity of the collaborative writing process as it unfolds turn-by-turn during their interactions. This type of analysis permits researchers to explore how learners orient to their partners and to the language they are producing, and what learners do with their talk (Markee, 2000), so that researchers can observe their competence-in-action (Pekarek Doehler, 2013). The discursive …

Campus Chronicle, Laisha Barguiarena, Lily Hastings, Maria Hernandez, Lucy Hernandez, Emily Houck, Nick Longo, Sam Metcalf, Alyssa Monroe, Anastasia Crist, Tony Napier, Andy Langager

Campus Chronicle

No abstract provided.

March 1, 2023 Faculty Senate Minutes, University Of South Carolina

Faculty Senate

No abstract provided.

Developing Model Federal Legislation To Advance Safe And Responsible Ocean Carbon Dioxide Removal Research In The United States, Romany M. Webb, Korey Silverman-Roati

Sabin Center for Climate Change Law

This model federal legislation aims to advance safe and responsible ocean carbon dioxide removal (CDR) research in U.S. waters. Controlled field trials and other in-ocean research is critical to improve scientific and societal understanding of CDR techniques that could help the U.S. reach its climate goals. However, existing legal frameworks were not designed to regulate ocean CDR and, in some cases, unnecessarily or inappropriately restrict needed research. The purpose of this proposed model legislation is to establish clear and efficient permitting regime for in-ocean CDR research. At the same time, the model legislation builds in consultation, monitoring, and other safeguards …

Credit Union Servant Leadership Encourages Financial Literacy, Darrell Jensen

Doctor of Strategic Leadership (DSL) Capstone Abstracts

Project Type

Organizational Change Initiative

Project Overview

January 1, 2023, Midflorida Credit Union rolled out an online financial literacy platform to 1300 employees. April 1, 2023, as part of Financial Literacy month, it will be rolled out to over 400,000 members. This project supports Midflorida’s mission statement, “To improve the well-being of our members.”

Project Themes

The financial literacy project consisted of a three-phase rollout of planning, implementation, and future phases. Phase one established the teams, product review, and contract negotiations. Phase two was content review, modifications, security review, training, and employee surveys. Phase three is the servant leadership training …

Efficacy Of Biofungicides And Their Application Timing In Managing Botrytis Bunch Rot Of Wine Grape, Marco A. Fernandez

Master's Theses

Botrytis bunch rot (BBR), caused by Botrytis cinerea, leads to a severe reduction of quality and yield in wine grapes (Vitis vinifera). A field study to determine the best BBR management strategy was conducted in 2021 and 2022 in Santa Maria, CA using ‘Chardonnay’, a BBR susceptible wine grape cultivar. Three biofungicides were evaluated: Actinovate® AG, Regalia®, and Serenade® ASO. The efficacy of these three biofungicides was compared with fungicide programs composed of commonly used synthetic fungicide(s) or combinations of commonly used synthetic and biofungicides. For each biofungicide, three application timings were evaluated: 7-day interval, 14-day interval, and by an …

Comorbid Mental Illness In Adults Correspond With Certain Demographics And Higher Rates Of Injuries And Poisoning, Mckay A. Ashton, Ray M. Merrill

Library/Life Sciences Undergraduate Poster Competition 2023

• Mental illness is a common problem among adults aged 18 years and older in the United States, with approximately 21% (15.8% men and 25.8% women) of the population living with a mental, behavioral, or emotional disorder.
• Comorbidity is the presence of at least one other mental health disorder in relation to the index disorder, and has been found to be present in 45% to 54% of those with a mental health disorder
• Although it is well understood that the prevalence of comorbid mental health disorders is common, there is less known about which conditions most commonly occur together and how …

Why Some People Are Hesitant To Receive Covid-19 Boosters: A Systematic Review, Yam B. Limbu, Bruce A. Huhmann

Department of Marketing Faculty Scholarship and Creative Works

As the COVID-19 pandemic continues and transitions to an endemic stage, booster vaccines will play an important role in personal and public health. However, convincing people to take boosters continues to be a key obstacle. This study systematically analyzed research that examined the predictors of COVID-19 booster vaccine hesitancy. A search of PubMed, Medline, CINAHL, Web of Science, and Scopus uncovered 42 eligible studies. Globally, the average COVID-19 booster vaccination hesitancy rate was 30.72%. Thirteen key factors influencing booster hesitancy emerged from the literature: demographics (gender, age, education, income, occupation, employment status, ethnicity, and marital status), geographical influences (country, region, …

Table Of Contents, Editorial Board, Law School Faculty And Administration, University Of Nevada, Las Vegas -- William S. Boyd School Of Law

Nevada Law Journal

No abstract provided.

Continuing Principled Sentencing Reform And Winding Back Mass Incarceration Against The Backdrop Of America’S Surge In Violent Crime, Mirko Bagaric, Jennifer Svilar, Brienna Bagaric

Nevada Law Journal

No abstract provided.

150 Years On: Common Sense Updates To The Mining Law Of 1872 To Address Our Changing Climate, Jake Ward-Herzik

Nevada Law Journal

No abstract provided.

The Case For A Cda Section 230 Notice-And-Takedown Duty, Michael L. Rustad, Thomas H. Koenig

Nevada Law Journal

No abstract provided.

Predicting Fecal Indicator Bacteria Using Spatial Stream Network Models In A Mixed-Land-Use Suburban Watershed In New Jersey, Usa, Tsung Ta David Hsu, Danlin Yu, Meiyin Wu

Department of Biology Faculty Scholarship and Creative Works

Good water quality safeguards public health and provides economic benefits through recreational opportunities for people in urban and suburban environments. However, expanding impervious areas and poorly managed sanitary infrastructures result in elevated concentrations of fecal indicator bacteria and waterborne pathogens in adjacent waterways and increased waterborne illness risk. Watershed characteristics, such as urban land, are often associated with impaired microbial water quality. Within the proximity of the New York–New Jersey–Pennsylvania metropolitan area, the Musconetcong River has been listed in the Clean Water Act’s 303 (d) List of Water Quality-Limited Waters due to high concentrations of fecal indicator bacteria (FIB). In …

Transition Town Media - What Do Transition Towns Bring To The Table?, Sari Steuber, Skip Shuda

Sustainability Research & Practice Seminar Presentations

Sari Steuber and Skip Shuda, Transition Town Media - What do Transition Towns Bring to the Table?

The Impact Of Reimbursement For Non-Face-To-Face Chronic Care Management On Comprehensive Metabolic Biomarkers Among Multimorbid Patients With Type 2 Diabetes, Yixue Shao, Charles Stoecker, Dongzhe Hong, Elizabeth Nauman, Vivian Fonseca, Gang Hu, Alessandra N. Bazzano, Daniel Fort, Edmond K. Kabagambe, Lizheng Shi

Population and Public Health Science Faculty Publications

Aims: We evaluated the impact of reimbursement for non-face-to-face chronic care management (NFFCCM) on comprehensive metabolic risk factors among multimorbid Medicare beneficiaries with type 2 diabetes in Louisiana. Materials and Methods: We implemented a propensity score method to obtain comparable treatment (n=1501 with NFFCCM) and control (n=17,524 without NFFCCM) groups. Patients with type 2 diabetes were extracted from the electronic health records stored in REACHnet. The study period was from 2013 to February 2020. The comprehensive metabolic risk factors included the primary outcome of glycated hemoglobin (HbA1c) (as the primary outcome) and the secondary outcomes of body mass index (BMI), …

Reproducibility And Determinants Of The Metabolic Responses During A Mixed-Meal Tolerance Test, Emma J. Stinson, Paolo Piaggi, Cassie M. Mitchell, Leanne M. Redman, Jonathan Krakoff

Clinical Research Faculty Publications

Objective: The aim of this study was to assess the reproducibility and physiological determinants of mixed-meal tolerance tests (MMTTs) on glucose and insulin responses. Methods: While inpatients on a weight-maintaining diet, 894 individuals (574 with normal and 267 with impaired glucose regulation and 53 with type 2 diabetes [T2D]) underwent 9-hour MMTTs (breakfast and lunch; 30% weight-maintaining diet each; 40% carbohydrate, 40% fat, and 20% protein). Total/incremental areas under the curve (AUC/iAUC) were calculated from MMTT plasma glucose/insulin concentrations. Acute insulin response (AIR) was quantified by intravenous glucose tolerance test and insulin action (M) via hyperinsulinemic-euglycemic clamp. A subset had …

Muhlenberg Magic, Lehigh Valley Health Network

LVHN documents

No abstract provided.

Analytics Monthly, Lehigh Valley Health Network

LVHN documents

No abstract provided.

Quiet Quitting Or Acting Your Wage: What Does This Mean In Libraries?, Annie Epperson, Stephen Sweeney, Emily Masters, Miranda Wisor

University Libraries Publications

We explore the history and current meaning of an age-old concept of working to the rule, or, having a job that doesn't consume your life. In this interactive session, librarians from public, academic, and school settings explore the topic through a variety of lenses, including the individual impetus, institutional or structural impact, legal implications, issues of equality between front-line workers and administration, and the possible political solution to worker burnout.

Field Applications Of Zein As A Precise Nanoscale Delivery System For Methoxyfenozide, C. A.R. Bonser, C. Tamez, J. C. White, C. E. Astete, C. M. Sabliov, J. A. Davis

Faculty Publications

When insecticides are applied in the environment, much of the product does not reach the target pest. Biopolymeric nanoparticles as nanocarriers have the potential to improve insecticide efficacy by improving absorption, coverage, and permeability while protecting the insecticide active ingredient from abiotic conditions and extending efficacy through controlled release. We conducted a series of experiments using a biopolymeric nanoparticle synthesized from zein, a biodegradable maize protein, to compare efficacy of a nanodelivered hydrophobic insect growth regulator (methoxyfenozide) against a commercial formulation. Positively charged zein nanoparticles (empty and loaded with methoxyfenozide) were compared to the formulated product, Intrepid 2F, as a …

Impact Of Nonconventional Selection By Insecticides On Susceptibility Of The Southern House Mosquito, Culex Quinquefasciatus, Vivek Pokhrel, James A. Ottea

Faculty Publications

Mosquitoes are an important target of pest control as they vector pathogens that are associated with many debilitating human diseases. Given that mosquitoes have been selected with insecticides for over 100 years, much is known about the development of insecticide resistance associated with targeted application against populations of these insects. However, off-target selection by applications of insecticides in agricultural and residential sites also impacts development of insecticide resistance and is understudied. Similarly, the impact of selecting one life stage of mosquitoes on the insecticide susceptibility of different life stages is largely unknown. Here, we show that susceptibility to chlorantraniliprole, which …

Recent Advances And Challenges In Implementing Ipm Programmes In The Entomological Context Of Indian Agriculture, Ruchika Geedi, Gadi V.P. Reddy

Faculty Publications

Integrated pest management (IPM) programmes are based on using multiple methods to maintain nuisance insects below tolerant levels in crop fields. Recent advances in IPM in developed countries have incorporated biological pesticides, microbial products, semiochemicals, and beneficial insects, but few of such programmes have been successfully implemented in developing countries, such as India. Semiochemicals play critical roles as signals in various interspecific and intraspecific interactions between insects and plants, and among interacting insects, plants, and microbes. In India IPM programmes have included mechanical, chemical, cultural, and biological management strategies. However, among these methods, biological management has its own limitations. Indian …

A Draft Of The Genome Of The Gulf Coast Tick, Amblyomma Maculatum, Jose M.C. Ribeiro, Natalia J. Bayona-Vásquez, Khemraj Budachetri, Deepak Kumar, Julia Catherine Frederick, Faizan Tahir, Brant C. Faircloth, Travis C. Glenn, Shahid Karim

Faculty Publications

The Gulf Coast tick, Amblyomma maculatum, inhabits the Southeastern states of the USA bordering the Gulf of Mexico, Mexico, and other Central and South American countries. More recently, its U.S. range has extended West to Arizona and Northeast to New York state and Connecticut. It is a vector of Rickettsia parkeri and Hepatozoon americanum. This tick species has become a model to study tick/Rickettsia interactions. To increase our knowledge of the basic biology of A. maculatum we report here a draft genome of this tick and an extensive functional classification of its proteome. The DNA from a single …

Using Automated Speech Processing For Repeated Measurements In A Clinical Setting Of The Behavioral Variability In The Stroop Task, Terje B. Holmlund, Alex S. Cohen, Jian Cheng, Peter W. Foltz, Jared Bernstein, Elizabeth Rosenfeld, Bruno Laeng, Brita Elvevåg

Faculty Publications

The Stroop interference task is indispensable to current neuropsychological practice. Despite this, it is limited in its potential for repeated administration, its sensitivity and its demands on professionals and their clients. We evaluated a digital Stroop deployed using a smart device. Spoken responses were timed using automated speech recognition. Participants included adult nonpatients (N = 113; k = 5 sessions over 5 days) and patients with psychiatric diagnoses (N = 85; k = 3–4 sessions per week over 4 weeks). Traditional interference (difference in response time between color incongruent words vs. color neutral words; M = 0.121 s) and facilitation …

Physical Activity And Weight Loss In A Pragmatic Weight Loss Trial, Peter T. Katzmarzyk, Emily F. Mire, Corby K. Martin, Robert L. Newton, John W. Apolzan, Kara D. Denstel, William D. Johnson, Phillip Brantley, Ronald Horswell, Benjamin F. Springgate, Terry C. Davis, Connie L. Arnold, Eboni Price-Haywood, Carl J. Lavie, Vivian A. Fonseca, Tina K. Thethi, Jonathan Gugel, Kathleen B. Kennedy, Daniel F. Sarpong

Clinical Research Faculty Publications

The purpose of this study was to determine the association between changes in physical activity and changes in body weight in a cluster-randomized weight loss trial conducted in an underserved population in Louisiana. This study reports analyses conducted in the intervention group only, which was a 24-month multi-component weight loss program delivered by health coaches embedded in primary care clinics. Physical activity was assessed at baseline and at 6, 12, and 24 months of follow-up and changes in body weight were expressed as percent weight change from baseline. Among the sample of 402 patients, percent changes in body weight (mean …

Electronic Cigarette Nicotine Flux, Nicotine Yield, And Particulate Matter Emissions: Impact Of Device And Liquid Heterogeneity, Eric K. Soule, Shannon Mayne, William Snipes, Elizabeth K. Do, Travis Theall, Christoph Höchsmann, Soha Talih, Corby K. Martin, Thomas Eissenberg, Bernard F. Fuemmeler

Clinical Research Faculty Publications

Introduction: Electronic cigarettes (ECIGs) heat a nicotine-containing liquid to produce an inhalable aerosol. ECIG power (wattage) and liquid nicotine concentration are two factors that predict nicotine emission rate ("flux"). These factors can vary greatly across devices and users. Aims and Methods: The purpose of this study was to examine ECIG device and liquid heterogeneity in "real world"settings and the association with predicted nicotine flux, nicotine yield, and total particulate matter (TPM) emissions. Past 30-day ECIG users (n = 84; mean age = 23.8 years [SD = 9.6]) reported device and liquid characteristics. Device power was measured via multimeter, device display …