Digital Commons Network^™

Imc-Denoise: A Content Aware Denoising Pipeline To Enhance Imaging Mass Cytometry, Peng Lu, Karolyn A Oetjen, Diane E Bender, Marianna B Ruzinova, Daniel A C Fisher, Kevin G Shim, Russell K Pachynski, W Nathaniel Brennen, Stephen T Oh, Daniel C Link, Daniel L J Thorek

2020-Current year OA Pubs

Imaging Mass Cytometry (IMC) is an emerging multiplexed imaging technology for analyzing complex microenvironments using more than 40 molecularly-specific channels. However, this modality has unique data processing requirements, particularly for patient tissue specimens where signal-to-noise ratios for markers can be low, despite optimization, and pixel intensity artifacts can deteriorate image quality and downstream analysis. Here we demonstrate an automated content-aware pipeline, IMC-Denoise, to restore IMC images deploying a differential intensity map-based restoration (DIMR) algorithm for removing hot pixels and a self-supervised deep learning algorithm for shot noise image filtering (DeepSNiF). IMC-Denoise outperforms existing methods for adaptive hot pixel and background …

Endnotes

Sustainable Development Law & Policy

No abstract provided.

Using Federal Public Lands To Model A New Energy Future: Why The Biden Administration Should Prioritize Renewable Energy Development On Public Lands, Meghen Sullivan

Sustainable Development Law & Policy

Oil and gas extraction on public lands and waters is responsible for twenty percent of U.S. greenhouse gas emissions. If American public lands were their own country, they would be the fifth-largest greenhouse gas emitter in the world. As of 2020, only twenty percent of total U.S. electricity generation came from renewable energy sources. While renewable energy development on public lands has increased, most renewable energy comes from private lands. However, public lands contain immense renewable energy potential; for example, it is estimated that half of this country’s geothermal resources are found on public lands. Despite underutilized renewable energy potential …

Crumbling Crown Jewels: Addressing The Impact Of Recreational Overuse In America's National Parks, Ellen Spicer

Sustainable Development Law & Policy

National Parks are the “crown jewels” of America. However, in recent years they have become subjected to rampant overcrowding and overuse, so much so that they are being loved to death. The 1916 National Park Service (“NPS”) Organic Act calls for the conservation of “the scenery and the natural and historic objects and the wild life . . . and to provide for the enjoyment of the same in such manner and by such means as will leave [park sites] unimpaired for the enjoyment of future generations.” Due to increased visitation, one of the mandates of the NPS is being …

Pedal Into The Future, Elliot Wiley

Sustainable Development Law & Policy

Congress severely weakened the Electric Bicycle Incentive Kickstart for the Environment Act (E-Bike Act) when the bill was absorbed into the Build Back Better Bill. Electricity is the future, yet Congress has defanged a bill that could create significant progress in making bicycling a more accessible option for commuters.

Making Room For The Past In The Future: Managing Urban Development With Cultural Heritage Preservation, Kubra Guzin Babaturk

Sustainable Development Law & Policy

Few would disagree that art and architecture are indispensable aspects of the collective human experiences. But can there be “too much” of it? How much is “too much?” Could art and cultural heritage be a hindrance to progress, urbanization, and sustainability? Which art is worth saving? A growing question is how to balance and reconcile expanding urban needs with efforts to preserve cultural heritage. Many cities across the global face this fresh moral dilemma. Cities like Istanbul, Rome, and Cairo––heirs to great empires, with history and art cursing through every alley, are still modern-day metropolises, with ever-burgeoning populations and social …

Toward A Utah Intentionally Created Surplus Program, Devin Stelter

Sustainable Development Law & Policy

The Colorado River Basin continues to face a now two decade-long drought sparked by the drastic effects of climate change on the region. Climate forecasting predicts that the adverse effects of climate change will only increase in severity in years to come. These effects have led federal, state, tribal, and private actors operating in the basin to search for innovative and effective solutions to the significant water scarcity problems that will persist into the future. A closely linked threat stemming from Colorado River water scarcity is the prospect of a “Compact call” on Upper Basin water by the Lower Basin …

About Sdlp, Sdlp

Sustainable Development Law & Policy

The Sustainable Development Law & Policy Brief (ISSN 1552-3721) is a student-run initiative at American University Washington College of Law that is published twice each academic year. The Brief embraces an interdisciplinary focus to provide a broad view of current legal, political, and social developments. It was founded to provide a forum for those interested in promoting sustainable economic development, conservation, environmental justice, and biodiversity throughout the world.

Editor's Note, Juliette Jackson, Bailey Nickoloff

Sustainable Development Law & Policy

The Sustainable Development Law and Policy Brief (“SDLP”) is celebrating twenty-two years of legal scholarship on issues related to environmental, energy, natural resources, and international development law. SDLP continues to provide cutting-edge solutions to these legal issues in the face of the global COVID-19 Pandemic, while also transitioning back into a “new normal.” This issue is no different, as we published articles challenging our lawmakers and policy heads to address the impending needs of our communities to develop more sustainable infrastructure—needs that are only exacerbated by man-made climate change. We are proud of the work published, and we are forever …

Left-Behind Bangladeshi Wives Of Muslim Male Migrants In New York: A Critique Of Vivek Bald’S Bengali Harlem And The Lost Histories Of South Asian America, Prerana Das

Journal of International Women's Studies

Vivek Bald wrote Bengali Harlem and the Lost Histories of South Asian America to trace the untold story of Muslim Bengali men’s migration from British colonial Bengal throughout the 19th and 20th centuries and integration into the U.S. during the Asian exclusion era. This book review deconstructs gaps around Muslim women’s representation within Bengali Harlem through three analytical frameworks: self-orientalization and differential assimilation; masculinities and transnational migration; and the biopolitics of the racialized female body. This review aims to question how patriarchal constructions of Muslim masculinity impact men’s decisions to migrate and establish communities in New York. It explores how …

The Case For Working With Feminist New Materialisms Against The Dualisms That Divide Us, Ștefania Chihaia

Journal of International Women's Studies

This paper provides a theoretical overview of dualisms which lie at the foundation of Western thought in an attempt to highlight the fundamental contribution that feminist new materialisms bring to sociological theory and practice and beyond. To delineate the oppressive patterns of thought generated by anthropocentric dualistic thinking, I will draw on the influential works of ecofeminist Val Plumwood, science studies scholar and feminist Donna Haraway, and feminist theorist Karen Barad within the material turn. The exploration begins with an analysis of the Cartesian subject-object dichotomy rejected by post-humanists and new materialists, a dichotomy which spawns many others, and continues …

Artificial Intelligence-Altered Videos (Deepfakes), Image-Based Sexual Abuse, And Data Privacy Concerns, Chidera Okolie

Journal of International Women's Studies

Artificial Intelligence (AI) is a phenomenon that has become embedded in human life, and this symbiotic relationship between technology and humanity is here to stay. One such use of AI is deepfakes. The use of AI for deepfakes is arguably one of the most controversial topics because it raises ethical issues. Deepfakes are images or recordings that have been convincingly altered and manipulated to misrepresent someone as doing or saying something that they did not actually do or say. These manipulations thrive in the political arena and recently in the pornography industry, in which women’s faces are masked onto other …

Toward Inclusive Advancement: An Analysis Of Gender Equity In Kenya, Gloria Nyambura Kenyatta

Journal of International Women's Studies

This article assesses the notion of gender parity and its function towards inclusive advancement in the Kenyan context. Gender parity has been extensively acknowledged in the 2010 Constitution of Kenya, although its intended outcomes still need to be attained. Men and women have different needs, which should be harmonized for efforts geared towards achieving inclusive advancement. Both are entitled to equity in the advancement agenda. Through secondary research, this paper reviews the international, regional, and national frameworks on gender equity to which Kenya is a signatory. These frameworks are significant in supporting the country's efforts towards gender equity. The paper …

Feminism In Modern Japan: A Historical Review Of Japanese Women’S Issues On Gender, Polina Lukyantseva

Journal of International Women's Studies

This study primarily illustrates the evolution of the feminist movement in Japan by comparing two waves of the feminist movement. Furthermore, this paper examines the development of gender roles and gender bias in modern Japanese patriarchal society. It also illustrates and explains traditional roles, Japanese ideologies, the system of Fu-you (Jap. 扶養, Eng. dependent), and modern trends in contemporary Japan. In this study, the following qualitative research methods were applied. A thorough historical context analysis was done to comprehend the social dynamics, issues, and specifics of feminism in Japan, and the principle of historicism was used to illuminate and compare …

What Are The Attitudes Towards Changing Gender Roles Within The Saudi Family?, Rasis Alanazi, Munira Alhugail, Tagreed Almeshary

Journal of International Women's Studies

Saudi Vision 2030 was launched with a focus on three main themes: “a vibrant society,” “a thriving economy,” and “an ambitious nation” (2017). In order to realize these primary themes, more participation of women is required in the workforce. A number of legislative reforms have supported the entry of more women into the workforce, such as lifting the male guardian permission for work and travel, supporting programs for childcare, allowing women to drive cars, and ensuring women’s involvement in leadership positions. Saudi women are now working in defense, mining, construction, manufacturing, and retail among other sectors. As a result, women's …

Iranian Women's Movement: Political Opportunities And New Forces, Hamid Sajadi

Journal of International Women's Studies

The Iranian women's movement emerged and was sustained in an unprecedented way, although neither the movement's procedure nor the nature of the Iranian protesters' economic and social demands throughout the course of the previous ten years made its formation plausible. While unions have traditionally coordinated many Iranian protests, the present women's movement is non-union, has a national reach, and has been going strong for several months despite fierce government resistance. This study reviews the history and achievements of the women's protest movement in Iran since September 2022. In the past, women's activities have been severely constrained and suppressed by Iran's …

The Political Participation Of Women In Kenya, Gloria Nyambura Kenyatta

Journal of International Women's Studies

To tackle the historic marginalization of women in Kenya, the 2010 Constitution introduced reforms on the gender principle, the quota system, and decentralization to promote gender equality. Decentralization formed a localized political system that unlocked leadership positions to previously underprivileged sets of people like women in all the forty-seven devolved units. Worthy of note is that the elections of 2013 and 2017 had the highest number of women in Kenyan history both in the legislature and the executive branch; however, most government institutions did not attain the one-third gender rule, hence violating the Constitution. Achievement of gender equality in Kenya …

Eating Biodiversity: Investigating The Links Between Grassland Biodiversity And Quality Food Production, A. Hopkins, H. Buller, C. Morris, J. D. Wood

IGC Proceedings (1977-2023)

Modern food production systems are generally detrimental to biodiversity, and the widespread loss of species-diverse grassland as a consequence of intensive farming methods is well documented. Since the 1980s, a range of policy measures and financial incentives for farmers have been introduced in Europe to halt (and in some cases, reverse) this trend, primarily to meet environmental objectives of species and habitat conservation and landscape protection. Biodiversity, where associated with agricultural production, has largely been regarded as a positive 'externality' to the process of food production; a ‘product’ which benefits wider society without necessarily conferring an agricultural benefit to the …

Soil, Plant And Livestock Interactions In Australian Tropical Savannas, L. P. Hunt, T. Z. Dawes-Gromadzki

IGC Proceedings (1977-2023)

This paper considers the various soil, plant and livestock interactions occurring in Australia’s wet-dry savanna rangelands. These regions are relatively intact compared to most of the world’s rangelands. However there is increasing pressure for more intensive use of the landscape, especially from pastoralism. This potentially threatens landscape health, function and productivity through reduced soil health and a loss of digestible perennial plants, especially given the low soil fertility and highly variable rainfall characteristic of these regions. There is an obvious need for understanding these impacts to devise sustainable management practices that promote soil health and viable perennial plant communities, and …

Symposium: The Future Of Reproductive Rights: Dobbs And Unenumerated Parental Custody Rights And Interests, Jeffrey A. Parness

ConLawNOW

This article addresses issues involving custodial parents after Dobbs. It first briefly describes the federal constitutional right to an interest in custodial parentage under pre-Dobbs U.S. Supreme Court precedents. It finds few precedents on defining parents at birth and no precedents on defining parentage arising from post-birth acts. The paper then reviews Dobbs, particularly its varying takes on unenumerated constitutional rights. Finally, it explores how Dobbs should influence future precedents on federal constitutional custodial parentage that arises either at birth or after birth. It urges federal courts to expand custodial parentage in light of societal changes in …

Andean Pastures In The Fourth Region Of Chile: Marginal Lands And Vital Spaces For A Transhumance System, T. S. Koné, R. Osorio, J. -M. Fotsing

IGC Proceedings (1977-2023)

In the fourth region of Chile, the high Andean pastures between Chile and Argentina are the summer destination for transhumant shepherds and sustain a part of the regional livestock. Since 2000, Chile has prohibited the passage of livestock to Argentina for animal health reasons in spite of official registers indicating that 60 to 75% of the summer transhumance livestock had an Argentine destination. Under those conditions it is questionable whether the Andean Chilean grasslands can absorb the increased pastoral demand without suffering damage. The objective is to provide elements of an answer to this question regarding the distribution and availability …

Asthma & Copd Treatment Guideline Updates, Elaina Lioudis, Michael Do, Bona Shin

Transformative Medicine

This article provides a summary of the newly updated asthma and COPD treatment guidelines. The Global Initiative for Asthma (GINA) treatment guidelines were updated in 2022. The Global Initiative for Chronic Obstructive Lung Disease (GOLD) treatment guidelines were updated in 2023. Both the GINA and GOLD treatment guidelines are published by Science Committees composed of physicians from various countries; the Science Committees meet twice yearly to review published literature and update the guideline recommendations if necessary. The purpose of this article is to highlight some of the important updates to the GINA and GOLD treatment guidelines.

“I Have Dizziness, Do I Need A Pacemaker?”, Ravi Choxi, Arun Kundra

Transformative Medicine

No abstract provided.

Preparedness For And Management Of Conditions Of The Skin, Louis D. Mancano Md

Transformative Medicine

Over one-quarter of the US population seeks treatment for a dermatologic condition each year. Studies have indicated that the general medical school curriculum places little emphasis on diseases of the skin, and physicians may be ill-prepared to diagnose and manage these conditions. A better understanding of the seven corticosteroid classes and the variety of vehicles in which they are formulated may improve patient satisfaction, patient adherence, and clinical response to treatment when managing conditions of the skin.

Delay In Diagnosis Of Pd-1 Inhibitor Induced Secondary Adrenal Insufficiency, Olubunmi Oladunjoye, Ibiyemi Oke, Ian Garrahy, Adeolu O. Oladunjoye, Kyle Macaulay, Jeremy Ellis

Transformative Medicine

Introduction: Immune checkpoint inhibitors including PD-1 inhibitors, were initially approved for the treatment of metastatic melanoma but are now increasingly being used for different types of solid organ malignancies. Despite the important clinical benefits, they are associated with immune-related adverse events. The most critical endocrinopathy associated with PD -1 inhibitor is adrenal insufficiency (AI), which requires prompt diagnosis and management to avoid fatality.

Case presentation: We present the case of a 78-year-old woman with colon adenocarcinoma treated with Nivolumab (PD-1 inhibitor) after her pulmonary metastases progressed on chemotherapy. She presented to the hospital with progressive generalized weakness, fatigue, headache, lightheadedness, …

A Brief Literature Review Of The Impact Of Covid-19 On Eating Disorders In Adolescents, Sreya Muchivolu, Eduardo Espiridion

Transformative Medicine

COVID-19 was an unprecedented time for the entire world. As cases rapidly rose globally, the primary focus was on preventing further spread of the virus and taking care of acutely ill patients. Unfortunately, this meant that getting adequate care for other chronic conditions, including eating disorders (EDs), was a lower priority. Adolescents with EDs were a particularly vulnerable population, as their source of social support and normalcy in the form of school and in-person activities was removed with social distancing and lockdowns. The purpose of this paper is to investigate how COVID-19 affected EDs in adolescents, including likelihood of accessing …

Joyce's Representation And Experience Of Disability, Carrie Kancilia

James Joyce Literary Supplement

No abstract provided.

Interventions To Improve Teacher Self-Efficacy Beliefs About Writing And Writing Instruction: Lessons Learned And Areas For Exploration, Jadelyn Abbott, Tracey Hodges, Sherry Dismuke, Katherine Landau Wright, Claire Schweiker

Teaching/Writing: The Journal of Writing Teacher Education

The present study explores the findings of a systematic literature review of research about teachers’ self-efficacy for writing and writing instruction to demystify what is known and what remains unknown. We analyzed the pool of research on self-efficacy for writing and writing instruction from January 1992 to August 2020. Our final inclusion of articles resulted in 22 articles that examine teacher self-efficacy for writing and writing instruction while meeting our standards of examining changes in self-efficacy. We examined how shifts in self-efficacy are measured, specific interventions that increase teachers’ self-efficacy for writing and writing instruction as well as interventions that …

Unpacking Writer Identity: How Beliefs And Practices Inform Writing Instruction, David Premont

Teaching/Writing: The Journal of Writing Teacher Education

Although identity research is common in educational studies, little research explores the connections between identity and pedagogy, and far fewer specifically examine how writer identity influences writing pedagogy. Additional research exploring the connection between writer identity and writing pedagogy is necessary to offer nuanced teaching strategies to strengthen writing pedagogy. The present study explores the connections between writer identity and writing pedagogy for three preservice English teachers with strong writer identities during their respective student teaching experiences. Interview data were utilized to explore writer identity and analyse connections to writing pedagogy through In Vivo coding in this narrative inquiry. Findings …

A Pen, A Pencil, Or A Keyboard: Writing Center Tutors’ Perceptions, Mirta Ramirez-Espinola

Teaching/Writing: The Journal of Writing Teacher Education

A Pen, A Pencil, or a Keyboard: Online Writing Center Tutors’ Perceptions

Author, Adjunct Faculty, Grand Canyon University

Abstract

Writing can be challenging for some students, even those who have graduated high school and are moving forward to higher learning. Thus, an idea about students and writing support led to a study about writing centers and the individuals responsible for supporting struggling writers. This qualitative case study explored the tutors’ perceptions of online writing tutoring and investigated how tutors perceive their work using both asynchronous and synchronous online tutoring modes at a 4-year university. Though the writing center participating in …