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Richard Henry Lee: His Life And Legacy As An American Founder And Ways He Reflected Christian Perspectives And Enlightenment Thought, Sarah Lee Beemer Apr 2026

Richard Henry Lee: His Life And Legacy As An American Founder And Ways He Reflected Christian Perspectives And Enlightenment Thought, Sarah Lee Beemer

Doctoral Dissertations and Projects

This doctoral dissertation examines the life of Richard Henry Lee, serving as a biography while also looking more closely at the ways Christianity and Enlightenment thought were reflected in Lee’s life and work. Given that Lee is less well known than many of the other American Revolutionaries and founders, this dissertation aims to create a greater awareness of the significant contributions that Lee made in the early history of the United States. In addition to serving as a military leader in Virginia during the American Revolutionary War, he served in a political capacity for decades, including in Virginia’s legislature and …

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Championing Success: A Transcendental Phenomenological Study On Higher Education Leadership’S Role In Supporting Women Of Color, Inez Annette Hayes Apr 2026

Championing Success: A Transcendental Phenomenological Study On Higher Education Leadership’S Role In Supporting Women Of Color, Inez Annette Hayes

Doctoral Dissertations and Projects

The purpose of this transcendental phenomenological study was to explore and understand the role of higher education leadership in providing institutional support to women of color. The lived experiences of women of color as students was analyzed to understand the factors influencing their persistence at higher education institutions nationwide. The theory guiding this study was Rendón’s theory of validation as a process that encourages and supports students’ academic and personal growth, initiated by both in-class and out-of-class influences. This study focused on the Central Research Question: How do leadership practices and institutional supports in higher education influence the persistence of …

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A Hermeneutic Phenomenological Study Exploring Inclusion Of Latinos In Higher Education In Bilingual Programs, Carmem Charette Apr 2026

A Hermeneutic Phenomenological Study Exploring Inclusion Of Latinos In Higher Education In Bilingual Programs, Carmem Charette

Doctoral Dissertations and Projects

The purpose of this hermeneutic phenomenological study was to understand the lived experiences of promoting the inclusion of Latino/a students through bilingual programs at higher education institutions in the United States. To include Latinos in higher education administrators redesigned courses originally taught in English into Spanish and Portuguese at several colleges and universities nationwide. This qualitative research was designed as a hermeneutic phenomenological study, and three data collection methods were used: journal prompts, individual interviews, and focus group interviews. Data were collected from educational leaders, including administrators, deans, faculty coordinators, advisers, and professors, who shared their perspectives and experiences as …

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Circumstances Surrounding Officer Involved Fatal Shootings, James Corrin Apr 2026

Circumstances Surrounding Officer Involved Fatal Shootings, James Corrin

Doctoral Dissertations and Projects

Over the past several years, there has been concern from mainstream media outlets, politicians, citizens, and community leaders that police officers in the United States engage in unjustified use of deadly force events within communities. This has led to violent protests across the country. Police reform and the de-funding of the police have been a crucial topic for debate and discussion. An argument has been made by some individuals that law enforcement officers involved in the fatal shootings of unarmed Black male citizens are racially motivated. The purpose of the following research is to identify if these arguments are valid. …

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The Lived Experiences Of Secondary Algebra Teachers Working With Students With Math Anxiety: A Phenomenological Study, Chanly Kong Henderson Apr 2026

The Lived Experiences Of Secondary Algebra Teachers Working With Students With Math Anxiety: A Phenomenological Study, Chanly Kong Henderson

Doctoral Dissertations and Projects

The purpose of this hermeneutic phenomenological study was to understand the lived experiences of working with students with math anxiety in algebra classrooms for secondary math teachers at the Sunflower School District in the Western United States. The study was guided by attentional control theory, which explains how anxiety disrupts attention and working memory. The central research question was: What are the lived experiences of secondary math teachers working with students with math anxiety in algebra classrooms? Ten participants were selected through purposeful sampling. Data were gathered through semi-structured interviews, focus group interviews, and a journal prompt, and were manually …

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The Unseen Realities: A Phenomenological Study Examining How K-12 Female Administrators' Experience Stress While Leading In Rural North Carolina, Danielle A. Perkins Apr 2026

The Unseen Realities: A Phenomenological Study Examining How K-12 Female Administrators' Experience Stress While Leading In Rural North Carolina, Danielle A. Perkins

Doctoral Dissertations and Projects

The purpose of this transcendental phenomenological study is to understand the lived experiences of K-12 female administrators in rural North Carolina public school districts. The theory guiding this study is the cognitive appraisal theory as it will explain the relationship between appraisal, work-related stress, coping, and the well-being of female K-12 administrators. The central research question for the research study is: How do K-12 female administrators describe their lived experiences with work-related stress in rural North Carolina public school districts? The study participants consist of 11 female K-12 administrators who are leading in rural public school districts in North Carolina. …

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Correlating Communication Channels With Baptism Outcomes: A Quantitative Case Study Using Media Multiplexity Theory In The Texas Conference Of Seventh-Day Adventists, Kenrunne L. Dixon Apr 2026

Correlating Communication Channels With Baptism Outcomes: A Quantitative Case Study Using Media Multiplexity Theory In The Texas Conference Of Seventh-Day Adventists, Kenrunne L. Dixon

Doctoral Dissertations and Projects

The purpose of this quantitative study was to examine the use of social media within the local church setting as a tool for engaging diverse communities through tailored, targeted messaging that addresses their unique needs and desires. The use of multiple channels helps connect on different levels, allowing for more profound and lasting relationships (Ledbetter, 2021). This quantitative research explored the local church and how it invests in connecting to its communities outside the church walls through multiple communication channels. Local church congregations invest significant time and resources in planning programs that seem only to attract current members. Their congregations …

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Exploring The Lived Experiences Of Operating Room Nurse Interns Transitioning To Practice: A Qualitative Study, Christina C. Baker Apr 2026

Exploring The Lived Experiences Of Operating Room Nurse Interns Transitioning To Practice: A Qualitative Study, Christina C. Baker

Doctoral Dissertations and Projects

The purpose of this transcendental phenomenological study was to describe the essence of the lived experiences of new graduate nurse interns transitioning to the operating room (OR) specialty at a southeastern U.S. university hospital system. Many hospitals have nurse residency programs designed to support and facilitate new nursing graduates’ transition to practice areas. The OR is a highly specialized nursing area requiring training in addition to what is offered in nurse residency programs. The central research question was, what is the lived experience of new graduate OR nurses as they complete their transition to practice programs? The theory guiding this …

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Exploring Mathematics Faculty Perceptions Of Instructional Design In Ai-Integrated Tools: A Phenomenological Study, Taylor Victoria Moreau Apr 2026

Exploring Mathematics Faculty Perceptions Of Instructional Design In Ai-Integrated Tools: A Phenomenological Study, Taylor Victoria Moreau

Doctoral Dissertations and Projects

The purpose of this transcendental phenomenological study was to explore the lived experiences of higher education mathematics faculty implementing artificial intelligence tools in their classrooms. The theory that guided this study was Piaget’s cognitive learning theory, which emphasizes that learners absorb knowledge by building upon previous understandings and experiences. The central research question guiding this study is: What are the lived experiences of mathematics faculty in higher education who utilize AI tools to support instructional design in their classrooms? Purposeful sampling was used to recruit full-time or visiting mathematics faculty members from four-year colleges and universities in the eastern United …

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The Development And Leadership Implementation Of Strategies Promoting Church Health In The Presbytery Of The Central West, New South Wales, Australia, Mark S. Armstrong Apr 2026

The Development And Leadership Implementation Of Strategies Promoting Church Health In The Presbytery Of The Central West, New South Wales, Australia, Mark S. Armstrong

Doctoral Dissertations and Projects

Many Churches in the Presbyterian rural landscape have plateaued or are in decline. Little research has been done to address the causes and provide strategies for remediation. This study examines this problem in the Presbytery of the Central West, New South Wales, Australia. The purpose of the project is to identify factors causing church decline in rural areas and develop revitalization strategies for ministers and elders across the Presbytery. The research consists of two layered responses. The first layer identifies factors causing church decline and develops five strategies suitable for implementation. The second layer utilizes Mezirow’s transformative learning framework to …

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Utilizing A Small Group In Bible Studies To Bring About The Reconciliation Of All The Groups Of An Ethnic Community Church In Brooklyn, New York, Anthony Ukasoanya E Uwakwe Apr 2026

Utilizing A Small Group In Bible Studies To Bring About The Reconciliation Of All The Groups Of An Ethnic Community Church In Brooklyn, New York, Anthony Ukasoanya E Uwakwe

Doctoral Dissertations and Projects

Many local churches in America today have problems in their ministries. The problems may stem from the untimely action or inaction by the church leaders, including ordained pastors and laity. Other problems are simple misunderstandings, such as a congregant not being reimbursed for funds used for a church event. This thesis research project will present biblical teachings on reconciliation, provide a framework for resolving financial misunderstandings in the church, and foster unity among its groups. It is important to know God’s reasons for being reconciled in the fellowship of the church. The triangular methodology employed uses specific scripture passages that …

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Cross-Gender Teaching Dynamics In Single-Gender Schools: A Case Study On School Leaders’ Perspectives On Gendered Teaching Practices, Support, And School Culture, Kelsie R. Copeman Apr 2026

Cross-Gender Teaching Dynamics In Single-Gender Schools: A Case Study On School Leaders’ Perspectives On Gendered Teaching Practices, Support, And School Culture, Kelsie R. Copeman

Doctoral Dissertations and Projects

The purpose of this comparative case study is to examine the gendered experiences of teachers through the perspective of school leaders at single-gender schools. The theory guiding this study is Tomlinson’s theory on differentiated instruction, as it explains how the recognition and response to student differences allows for effective teaching in order to optimize learning experiences. The central research question is: How do school leaders perceive and navigate cross-gender teaching dynamics in single-gender schools? This study uses semi-structured interviews, focus groups, and journal entries from school leaders. The sample consists of 10 school leaders with current experience in single-gender schools, …

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A Case Study Examining Why Students Succeed When Exposed To Peer Tutors, Van E. Carpenter Apr 2026

A Case Study Examining Why Students Succeed When Exposed To Peer Tutors, Van E. Carpenter

Doctoral Dissertations and Projects

The purpose of this instrumental case study was to identify the impact of online peer tutoring on students’ perceptions of their success for students who participated in online peer tutoring at Summit Faith University (a pseudonym used for this research). This research was grounded in Bandura’s self-efficacy theory, which provided a comprehensive framework for examining the factors influencing the effectiveness of peer tutoring among students. This study answered three research questions: How do online students use peer tutoring at Summit Faith University, how does online peer tutoring at Summit Faith University shape students’ perceptions of their success at Summit Faith …

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Professional Development In West Virginia's Rural Public Schools Relating To Secondary Math Teacher Retention: A Phenomenology Through The Lens Of Andragogy, Tanya L. Cooper Apr 2026

Professional Development In West Virginia's Rural Public Schools Relating To Secondary Math Teacher Retention: A Phenomenology Through The Lens Of Andragogy, Tanya L. Cooper

Doctoral Dissertations and Projects

The purpose of this qualitative transcendental phenomenological study was to explore the perceptions of factors related to professional development that influence the retention of secondary math teachers in West Virginia’s rural public schools. The theory guiding this study was adult learning theory, specifically Knowles’ andragogy, as it explains the perceptions of secondary math teachers from their perspective as adult learners. The Central Research Question was: What are rural secondary math teachers’ perceptions of factors related to professional development that influence retention? This phenomenological study was conducted in rural areas of West Virginia, examining the perceptions of ten secondary math teachers …

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A Phenomenological Approach To Exploring Emotional Dysregulation And Lack Of Empathy In Preschoolers From Low Income Christian And Non-Christian Families, Christine Mendez Apr 2026

A Phenomenological Approach To Exploring Emotional Dysregulation And Lack Of Empathy In Preschoolers From Low Income Christian And Non-Christian Families, Christine Mendez

Doctoral Dissertations and Projects

Children often apply the adaptive skills they learn at home to the classroom in preschool, marking their first experience in structured environments. Two constructs, emotional regulation and empathy, are behaviors necessary for a preschooler’s development. However, the absence of socially desirable contexts can lead to preschoolers developing academic and behavioral deficits. Existing literature does not explore the spiritual, social and cultural practices of the familial and academic environments of preschoolers from disadvantaged groups. Earlier studies from higher socioeconomic levels suggest that poor attachment during infancy, parenting skills, trauma or lack of age-appropriate learning opportunities are conditions that deteriorate regulation and …

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Amyotrophic Lateral Sclerosis Risk Perceptions And Patient Burden, John William Glisson Apr 2026

Amyotrophic Lateral Sclerosis Risk Perceptions And Patient Burden, John William Glisson

Doctoral Dissertations and Projects

This quantitative, non-experimental, cross-sectional correlational study examined relationships among perceived environmental risk factors, depressive symptoms, and functional symptom burden in adults diagnosed with Amyotrophic Lateral Sclerosis (ALS). ALS is a progressive neurodegenerative condition with an unclear etiology, and some individuals attribute the diagnosis to environmental exposures such as pesticides or military service. The purpose of this study was to assess whether environmental risk perceptions were associated with depressive symptoms or functional impairment, and whether depressive symptoms were associated with functional status. Participants were recruited through online ALS support networks and advocacy organizations, resulting in a final sample of 145 adults …

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Abusive Supervision In The Telecommunications Retail Sector: Effects On Job Satisfaction, Performance, And Employee Turnover, Zenitzia Siu Apr 2026

Abusive Supervision In The Telecommunications Retail Sector: Effects On Job Satisfaction, Performance, And Employee Turnover, Zenitzia Siu

Doctoral Dissertations and Projects

I addressed the problem of abusive supervision, which adversely affects job satisfaction and employee engagement, resulting in reduced organizational performance and increased turnover intentions in telecommunications retail. Guided by social exchange theory (SET), this qualitative single-case study explored how leaders interpret their awareness of their leadership behaviors, and how these interpretations align with or misalign with employees’ perceptions. The data collection involved 21 leader interviews and 25 open-ended survey responses, analyzed using SET’s deductive coding and NVivo's inductive theme development, with methodological triangulation across both data sources. Four core themes emerged deductively: (a) reciprocity, (b) trust and commitment, (c) cost …

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The Successful Transition Of Military Veterans To Higher Education: A Phenomenological Study, Kenneth Hollis Apr 2026

The Successful Transition Of Military Veterans To Higher Education: A Phenomenological Study, Kenneth Hollis

Doctoral Dissertations and Projects

The purpose of this hermeneutic phenomenological study was to explore the lived experiences of student veterans as they transition into 4-year universities in the southern region of the United States. The problem guiding this work is that student veterans often face significant challenges in achieving academic and personal success during the transition from military service to civilian campus life. The theory guiding this study was Schlossberg's transition theory, as it provides a framework for understanding the factors that influence individuals' experiences during change and transition how veterans navigate the academic, social, and psychological dimensions of this pivotal life change. The …

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The Experiences Of The Free Application For Federal Student Aid In Parents Of First-Generation College Students: A Phenomenological Study, Travis Anthony Richard Apr 2026

The Experiences Of The Free Application For Federal Student Aid In Parents Of First-Generation College Students: A Phenomenological Study, Travis Anthony Richard

Doctoral Dissertations and Projects

The purpose of this phenomenological study was to investigate the experiences of parents of first-generation college students in the Free Application for Federal Student Aid process. The theory guiding this study was the Cultural Capital Theory, initially conceptualized by Pierre Bourdieu, as it focused on how cultural capital was transmitted within families and how it reinforced class distinction. With the increasing emphasis on higher education as a pathway to socioeconomic mobility, understanding the barriers and facilitators faced by these parents was crucial. The central research question guiding this study is: "What are the lived experiences of parents of first-generation college …

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The Impact A Dynamic Team In Ministry Has On Seniors At Cornerstone Church: Discipleship Reviving Gadsden, Alabama, Abraham Gonzalez Ii Apr 2026

The Impact A Dynamic Team In Ministry Has On Seniors At Cornerstone Church: Discipleship Reviving Gadsden, Alabama, Abraham Gonzalez Ii

Doctoral Dissertations and Projects

Discipleship is a directive handed down through generations for the last two thousand years, as provided in Matthew 28:18-20. It has contributed to the growth of the universal church. As the church progressed, a recurring issue from within was recorded in the Bible. The ideology of traditions and culture being placed above the Scriptures is not foreign to the church; the Bible reflects this in the Gospels, like Matthew 23 (NASB, 1971/2020, Matthew 23). Jesus provided a visualization of discipleship that would aid the church in redirecting its trajectory back to focusing on him. Biblically, God has always provided senior …

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Online Simulation To Build Competence In Assessment And Documentation With Clients Experiencing Opioid Use Disorder, Lauren B. Mcinroy, Jacyln Kirsch, Oliver Beer, Katie Klakos, Catherine Hechmer, Julie Holston Apr 2026

Online Simulation To Build Competence In Assessment And Documentation With Clients Experiencing Opioid Use Disorder, Lauren B. Mcinroy, Jacyln Kirsch, Oliver Beer, Katie Klakos, Catherine Hechmer, Julie Holston

School of Health Professions

Synchronous simulation—an experiential learning approach replicating “real-world” practice contexts—offers important opportunities for social work students to apply course concepts, rehearse skills, and increase their competence. However, scant research has considered approaches to delivering synchronous simulation opportunities to students online. This case study examines the experiences of master of social work (MSW) students (n = 52) who participated in a synchronous online simulation activity designed to promote the development of students’ assessment and documentation skills in the context of working with a client with suspected opioid use disorder. Multiple data sources were leveraged, including activity recordings, exit surveys, and submitted materials. …

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The Barriers For Special Education Teachers During Covid-19: Beyond Instructional Changes, Eunjoo Kim, Jeongae Kang, Eunyoung Jung Apr 2026

The Barriers For Special Education Teachers During Covid-19: Beyond Instructional Changes, Eunjoo Kim, Jeongae Kang, Eunyoung Jung

Midwest Social Sciences Journal

Although special education teachers faced many challenges during the COVID-19 pandemic, far less is known about those details. This study investigated the barriers that special education teachers encountered during the COVID-19 pandemic. Using an online survey, the researchers gathered information about technology-related questions and three domains of the barriers: the teachers themselves, students, and parents/caregivers. The findings are: (1) the barriers extended beyond mere technology issues; (2) the barriers were multi-dimensional; (3) stronger collaboration between SETs and caregivers as needed; and (4) the home environment was highly dependent on the district’s support.

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Hurdles To Retirement Security: Exploring Race, Religion, And Savings Behavior, Mamoud A. Jalloh, Sedefka Beck Apr 2026

Hurdles To Retirement Security: Exploring Race, Religion, And Savings Behavior, Mamoud A. Jalloh, Sedefka Beck

Midwest Social Sciences Journal

Retirement savings have become increasingly central to household financial security as defined contribution plans replace traditional pensions. Using nationally representative data from the 2019 Panel Study of Income Dynamics, this study applies a double‑hurdle model to examine the distinct factors shaping participation in retirement plans and contribution intensity. Results reveal persistent racial and ethnic inequalities: Hispanic, Black, and Mixed‑Race workers are significantly less likely to save and contribute markedly less than White workers, even after accounting for income, wealth, and employment characteristics. Religious affiliation also influences savings behavior, with Jewish contributors saving more and several other groups saving less than …

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Author Biographical Notes Apr 2026

Author Biographical Notes

Midwest Social Sciences Journal

No abstract provided.

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Interferon-Induced Protein Ifit3 As A Molecular Nexus Of Neuroinflammation In Alzheimer’S Disease And Hiv-Associated Neurocognitive Disorders, Ranjit Kumar Das, Nirakar Sahoo, Deepa Roy, Lauren Nguyen, Hansapani Rodrigo, Asim K. Duttaroy, Jerel Adam Fields, Upal Roy Apr 2026

Interferon-Induced Protein Ifit3 As A Molecular Nexus Of Neuroinflammation In Alzheimer’S Disease And Hiv-Associated Neurocognitive Disorders, Ranjit Kumar Das, Nirakar Sahoo, Deepa Roy, Lauren Nguyen, Hansapani Rodrigo, Asim K. Duttaroy, Jerel Adam Fields, Upal Roy

Health & Biomedical Sciences Faculty Publications

Alzheimer’s disease (AD) and HIV-associated neurocognitive disorder (HAND) are significant global health concerns characterized by cognitive impairment and shared pathological features, including chronic neuroinflammation, amyloid deposition, and immune dysregulation. However, the precise molecular connections between these disorders remain unclear. Here, we identify IFIT3 as a critical shared mediator of neuroinflammatory responses in both AD and HAND. Using complementary approaches, including neuronal and microglial cell cultures, the APP/PS1 mouse model, and human postmortem brain tissues, we demonstrate consistent IFIT3 upregulation in response to amyloid-beta (Aβ) and HIV-1 exposure, with notably enhanced expression under combined conditions. Treatment with combination antiretroviral therapy (cART) …

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Editor-In-Chief's Note, Surekha Rao Apr 2026

Editor-In-Chief's Note, Surekha Rao

Midwest Social Sciences Journal

No abstract provided.

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Emotional Disclosure Dilemmas: How Personal And Relational Factors Predict Ambivalence Over Emotional Expression, Julie A. Tobin, Camilla S. Øverup, Qian Lu Apr 2026

Emotional Disclosure Dilemmas: How Personal And Relational Factors Predict Ambivalence Over Emotional Expression, Julie A. Tobin, Camilla S. Øverup, Qian Lu

Midwest Social Sciences Journal

Ambivalence over emotional expression (AEE) has been associated with various health and wellbeing outcomes, yet the relational factors that may be associated with AEE have been underexplored. The current study explored the associations between social support, conflict, gender, and AEE across a variety of different relationship types. Participants (N = 135) read scenarios describing situations where they imagined either expressing or suppressing different emotions (anger, pride, apprehension, appreciation) to five different people and then indicated the amount of regret (AEE) they anticipated over that expression decision. The results suggest that although social support was particularly related to emotional expression, …

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Rising Numbers, Rising Risks: Population, Growth, And Natural Disasters, Sophia Becker-Toro, Yu Ouyang Apr 2026

Rising Numbers, Rising Risks: Population, Growth, And Natural Disasters, Sophia Becker-Toro, Yu Ouyang

Midwest Social Sciences Journal

How does population size and growth affect the risk of natural disasters? On October 7, 2024, before Hurricane Milton makes landfall in the Tampa Bay area, Tampa Mayor Jane Castor issues a dire warning to affected citizens: “I can say without any dramatization whatsoever. If you choose to stay in one of those evacuation areas, you’re going to die.” While there is an extensive literature which focuses on the impact of climate change and/or natural disasters, there is a dearth of works on how population affects the risks of natural disasters. As both the frequency and severity of storms and …

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Developing Endpoints For The Cardiac Burden In Myotonic Dystrophy Type 1: A Workshop Report, Julia M Hartman, Samuel Carrell, William J Groh, Thomas A Cooper, Jordana Kron, Greg Hundley, Jennifer Jordan, Amy Ladd, Man Hung, Nicholas E Johnson Apr 2026

Developing Endpoints For The Cardiac Burden In Myotonic Dystrophy Type 1: A Workshop Report, Julia M Hartman, Samuel Carrell, William J Groh, Thomas A Cooper, Jordana Kron, Greg Hundley, Jennifer Jordan, Amy Ladd, Man Hung, Nicholas E Johnson

Faculty, Staff and Students Publications

Cardiac disease is a well-established manifestation of myotonic dystrophy type 1 (DM1), characterized by progressive cardiac conduction slowing with increased risk of atrial and ventricular arrhythmias, heart block, and sudden cardiac death. Multiple disease modifying therapies are in clinical trials for DM1 and show promise in improving skeletal muscle weakness and myotonia. Testing the effects of these medicines, or others, in the heart is of critical importance, but requires identification of endpoints of cardiac function that accurately reflect the state of DM1 cardiac disease. To better define cardiac endpoints, the Myotonic Dystrophy Clinical Research Network (DMCRN) and the Myotonic Dystrophy …

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Versatile Smad2 And Smad3 Epitope-Tagged Mouse Models For Genomic Profiling Of Tgfβ Signaling: Uncovering Gdf9-Smad2/3 Targets, Zian Liao, Qian Zhang, Keisuke Shimada, Kaori Nozawa, Suni Tang, Masahito Ikawa, Diana Monsivais, Martin M Matzuk Apr 2026

Versatile Smad2 And Smad3 Epitope-Tagged Mouse Models For Genomic Profiling Of Tgfβ Signaling: Uncovering Gdf9-Smad2/3 Targets, Zian Liao, Qian Zhang, Keisuke Shimada, Kaori Nozawa, Suni Tang, Masahito Ikawa, Diana Monsivais, Martin M Matzuk

Faculty, Staff and Students Publications

Transforming growth factor β (TGFβ) signaling pathways are integral for a plethora of biological processes. SMAD2 and SMAD3 are the principal transcriptional effectors of TGFβ superfamily ligands, yet quantitative, genome-wide mapping of their DNA-associated complexes under physiological contexts has remained limited due to the lack of specific, robust models. Here, we generated two versatile epitope-tagged mouse models in which endogenous SMAD2 and SMAD3 proteins are globally tagged with hemagglutinin (HA) and podoplanin (PA) sequences, respectively, enabling high-fidelity profiling of SMAD2 and SMAD3 binding across tissues. To demonstrate the broad application of our models, we exemplified the usage of our lines …

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