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Articles 23701 - 23730 of 1791794
Full-Text Articles in Entire DC Network
The Road To Senior Leadership: Senior-Level Administrative Women Leaders In Division I Intercollegiate Athletic Departments, Susan E. Richard
The Road To Senior Leadership: Senior-Level Administrative Women Leaders In Division I Intercollegiate Athletic Departments, Susan E. Richard
Electronic Theses and Dissertations
This qualitative narrative study examined the career pathways and lived leadership experiences of women serving in senior-level administrative roles within Division I intercollegiate athletics, a traditionally male-dominated industry. Guided by a crucible leadership framework, the study explored how formative experiences shaped participants’ leadership development, professional advancement, and persistence. Nine women who currently or previously served as senior-level administrative leaders participated in the study. Data were collected using an adapted version of Seidman’s three-interview series, supplemented by document analysis and a demographic survey to support triangulation. Interviews were organized into three phases to chronologically capture participants’ career trajectories.
The findings are …
Prmt5 Inhibition Impairs Fanconi Anemia Pathway-Mediated Homologous Recombination And Enhances The Antitumor Efficacy Of Temozolomide In Glioblastoma, Shumpei Onishi, Sridharan Jayamohan, Ashis Chowdhury, Sarah Rivas, Yoshihiro Otani, Celine Ertekin, Jean-Paul Bryant, Sara A Murphy, Kimberly A Rivera-Caraballo, Stuart Walbridge, Bayu Sisay, Dragan Maric, Abdel Elkahloun, Kory Johnson, Desmond A Brown, John D Heiss, Ashish H Shah, Tae Jin Lee, Sangamesh G Kumbar, Ji Young Yoo, Andrew J Brenner, Balveen Kaur, Gangadhara R Sareddy, Yeshavanth Kumar Banasavadi-Siddegowda
Prmt5 Inhibition Impairs Fanconi Anemia Pathway-Mediated Homologous Recombination And Enhances The Antitumor Efficacy Of Temozolomide In Glioblastoma, Shumpei Onishi, Sridharan Jayamohan, Ashis Chowdhury, Sarah Rivas, Yoshihiro Otani, Celine Ertekin, Jean-Paul Bryant, Sara A Murphy, Kimberly A Rivera-Caraballo, Stuart Walbridge, Bayu Sisay, Dragan Maric, Abdel Elkahloun, Kory Johnson, Desmond A Brown, John D Heiss, Ashish H Shah, Tae Jin Lee, Sangamesh G Kumbar, Ji Young Yoo, Andrew J Brenner, Balveen Kaur, Gangadhara R Sareddy, Yeshavanth Kumar Banasavadi-Siddegowda
Faculty, Staff and Student Publications
Despite multimodal therapy of surgical resection, radiation, and chemotherapy, glioblastoma patients show a dismal prognosis. Protein Arginine Methyltransferase 5 (PRMT5) is overexpressed in glioblastoma, and its inhibition imparts an anti-tumor effect. Tumor cells invariably develop resistance to Temozolomide (TMZ), the standard chemotherapeutic agent for glioblastoma. However, the mechanistic role of PRMT5 in treatment-resistant glioblastoma is unknown. Patient-derived glioma stem-like cells (GSCs), treated with PRMT5 inhibitor (LLY-283) or transfected with PRMT5-target-specific siRNA, were treated with TMZ and subjected to in vitro functional and mechanistic studies. The intracranial mouse xenograft model was used to test the in vivo antitumor efficacy of combination …
A Proposal To Examine Naturally Occurring Mindfulness And Correctional Officer Stress And Burnout, Anthony M. Nasrallah
A Proposal To Examine Naturally Occurring Mindfulness And Correctional Officer Stress And Burnout, Anthony M. Nasrallah
Undergraduate Theses
Correctional officers (COs) work in institutions characterized by high interpersonal demand, safety risk, and organizational complexity; as a result, they experience elevated rates of occupational stress, burnout, and mental-health disorders relative to the general workforce. At the same time, research in allied helping professions demonstrates that mindfulness and related contemplative practices can reduce stress and improve emotion regulation and well-being. However, little is known about whether COs’ own, pre-existing informal mindfulness practices are associated with lower on-the-job stress or burnout rather than formal training courses. This review integrates findings from qualitative studies, quantitative analyses, and systematic reviews to show what …
Resource Map Of Expenditures For Tennessee Children And Youth, Annual Report To The Legislature 2026, Tennessee. Commission On Children And Youth.
Resource Map Of Expenditures For Tennessee Children And Youth, Annual Report To The Legislature 2026, Tennessee. Commission On Children And Youth.
Resource Map Report
No abstract provided.
Subchronic Oral Exposure To Propylparaben Induces Endocrine Disruption And Genotoxicity In Male Rats, Sarah M. Moud, Najiah M. Alyamani
Subchronic Oral Exposure To Propylparaben Induces Endocrine Disruption And Genotoxicity In Male Rats, Sarah M. Moud, Najiah M. Alyamani
Saudi Toxicology Journal
ropylparaben (PP) is widely employed as a preservative in consumer products such as cosmetics, pharmaceuticals, and food items, prompting increasing safety apprehensions due to its possible endocrine-disrupting properties. A controlled experimental investigation was conducted to assess the toxicological effects of sub-chronic propylparaben exposure on the testes of adult male rats. Twenty adult male rats (n = 20) were randomly assigned to two groups (10 rats per group): a control group receiving distilled water and a treated group receiving PP orally at a dosage of 100 mg/kg body weight once daily for four consecutive weeks. This dosage was selected based on …
Process Evaluation Of The Cheers Automated A1c Follow-Up Reminder System In Primary Care, Heather E. Lewis
Process Evaluation Of The Cheers Automated A1c Follow-Up Reminder System In Primary Care, Heather E. Lewis
Doctoral Dissertations & Projects
Background: Missed diabetes follow-up contributes to suboptimal glycemic control in primary care. Health record embedded reminder systems may improve continuity of care, but process evaluation is needed to understand real-world implementation (Bugge, 2024; Rathod et al., 2024).
Objective: To evaluate fidelity, workflow processes, and reach of the Cheers automated A1c reminder program among adults with type 2 diabetes in primary care.
Methods: This retrospective process evaluation used EHR data guided by the CDC Program Evaluation Framework (CDC, 2024). Measures included reminder delivery, follow-up completion, fidelity, and contextual factors.
Results: Of 72 eligible patients, 26 met success criteria (36.1%); 92.0% completed …
Spontaneous Blood Oxygen Level Dependent Signals In Glioblastoma-Bearing And Aging Brains, Ki Yun Park
Spontaneous Blood Oxygen Level Dependent Signals In Glioblastoma-Bearing And Aging Brains, Ki Yun Park
Arts & Sciences Graduate Student Theses and Dissertations
Brain activity fluctuates across timescales from microseconds to decades, reflecting processes ranging from rapid synaptic transmission to slow neuromodulatory and homeostatic changes. Resting-state functional magnetic resonance imaging (rs-fMRI) captures the slow end of this spectrum (spontaneous blood oxygen level-dependent (BOLD) fluctuations over tens to hundreds of seconds), which reflect the integrated output of these underlying processes and are increasingly recognized as sensitive to both pathological and physiological brain states. The core of this thesis examines rs-fMRI as a biomarker for two clinical entities: glioblastoma and aging. Reliable biomarker development requires both methodological rigor and analytic breadth, knowing what the method …
Convergent Rna Pathophysiology In Amyotrophic Lateral Sclerosis, Hunter Lee Patterson
Convergent Rna Pathophysiology In Amyotrophic Lateral Sclerosis, Hunter Lee Patterson
Arts & Sciences Graduate Student Theses and Dissertations
This dissertation explores the connection between amyotrophic lateral sclerosis pathogenesis and RNA biology via two mechanisms: microRNA regulation of gene expression in the spinal cord and modulation of TDP-43 pathology through synthetic oligonucleotides. Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by selective loss of motor neurons in the brain and spinal cord that leads to progressive weakness. However, despite this shared clinical pattern the known causes of ALS are extremely varied. Only about 10% of ALS cases are familial while the other 90% occur sporadically. Even among that small fraction of familial cases, researchers have identified dozens …
Student Senate Meeting Minutes April 15, 2026, Student Senate-Winona State University
Student Senate Meeting Minutes April 15, 2026, Student Senate-Winona State University
Student Senate Meeting Minutes
This document is the official Winona State University Student Senate Minutes for April 15, 2026.
Bruen, Levels Of Generality, And Our Historical Tradition Of The Regulatory “Why”, Kevin K. Wang
Bruen, Levels Of Generality, And Our Historical Tradition Of The Regulatory “Why”, Kevin K. Wang
UC Law Constitutional Quarterly
To pass Second Amendment muster under New York State Rifle & Pistol Association v. Bruen, gun laws encompassed by the Amendment’s plain text must align with our nation’s historical tradition of firearm regulation. A challenged law comports with history and tradition when it is sufficiently analogous to historical regulations along two metrics: “how” and “why” the regulation burdens the right to keep and bear arms.
One glaring ambiguity leftover from Bruen is the level of generality at which courts, when analogizing between laws past and present, must frame a regulation’s “how” and “why”—an issue of major consequence. Characterizing the “how” …
The Body At The Mercy Of The State: Sama V. Hannigan And The Fragmented Right To Refuse Across State Lines, Mallory Yeates
The Body At The Mercy Of The State: Sama V. Hannigan And The Fragmented Right To Refuse Across State Lines, Mallory Yeates
UC Law Constitutional Quarterly
Courts have long recognized bodily autonomy as a core constitutional value. Yet, doctrine governing reproductive healthcare tells a different story. Sama v. Hannigan exposes the fragility of the right to refuse medical treatment, particularly for incarcerated patients whose claims must survive the demanding standard of qualified immunity. When physicians removed Carrie Rahat Sama’s ovary despite her explicit refusal, her constitutional claim failed because no precedent with sufficiently similar facts had previously condemned such conduct. This case reveals how the “clearly established” prong of qualified immunity can foreclose redress for blatant violations of autonomy.
This Note argues that the viability of …
Leadership Initiatives: International Public Health Internship, Jayden Bradley, Alana Campbell, Natalie Brooks, Lucy Mcclung, Kara Mabry, Brian Hack, Mindy Highley
Leadership Initiatives: International Public Health Internship, Jayden Bradley, Alana Campbell, Natalie Brooks, Lucy Mcclung, Kara Mabry, Brian Hack, Mindy Highley
2026 Celebration of Student Scholarship - Poster Presentations
No abstract provided.
Mental Health Stability Through Self-Care Techniques: A Mother's Perspective, Jessica L. Ross, Monica Himes
Mental Health Stability Through Self-Care Techniques: A Mother's Perspective, Jessica L. Ross, Monica Himes
2026 Celebration of Student Scholarship - Poster Presentations
No abstract provided.
2026 Celebration Of Student Scholarship Program And Abstracts, Morehead State University. Undergraduate Research Fellowship Program.
2026 Celebration Of Student Scholarship Program And Abstracts, Morehead State University. Undergraduate Research Fellowship Program.
2026 Celebration of Student Scholarship - Poster Presentations
No abstract provided.
United States V. Skrmetti: On Realism, Reason, And Hope, Marc Spindelman
United States V. Skrmetti: On Realism, Reason, And Hope, Marc Spindelman
UC Law Constitutional Quarterly
No abstract provided.
Mapping Serial Killer Life Pathways With Behavior Sequence Analysis, Morgann Lynn Brafford
Mapping Serial Killer Life Pathways With Behavior Sequence Analysis, Morgann Lynn Brafford
Walden Dissertations and Doctoral Studies
Although adverse childhood experiences (ACEs) are known to influence criminal behavior in adulthood, their potential influence on serial killer actions has not been scrutinized. This study was an investigation of how ACEs might affect serial killer actions later in life. The trauma-control model provided a conceptual framework for the investigation. Marono et al.’s research featuring behavior sequence analysis (BSA) was broadened to examine the impact of psychological abuse, sexual abuse, physical abuse, violence against animals, head injury, and bullying serial killer behaviors like stalking or sexual assault. The participants were 364 anonymized male serial killers from the Radford/Florida Gulf Coast …
Biophysical Insights Into A Cryptic, Hydrophobic Binding Site On Pcna, Alexis Dispensa
Biophysical Insights Into A Cryptic, Hydrophobic Binding Site On Pcna, Alexis Dispensa
Theses and Dissertations
Proteins are dynamic molecules whose functional landscapes extend beyond static structural representations. Transient cryptic pockets (buried cavities that emerge through protein motion) represent underexplored targets for allosteric regulation and drug discovery. General anesthetics are small, lipophilic, weakly polar molecules that are well suited to partition into such hydrophobic sites. In this work, environment-sensitive fluorescence, photoaffinity labeling, mass spectrometry, mutational analysis, and microsecond molecular dynamics simulations were integrated to discover and characterize a cryptic, highly apolar binding site within the hydrophobic core of human proliferating cell nuclear antigen (PCNA), a central scaffold in DNA replication and repair. Using the solvatochromic fluorescent …
Nature Nearby: Use Of Green Spaces Mediating The Relationship Between Access To Green Spaces And Health, Sydney P. Goodson
Nature Nearby: Use Of Green Spaces Mediating The Relationship Between Access To Green Spaces And Health, Sydney P. Goodson
FHSS Mentored Research Conference
Access to green spaces has been consistently linked to improved physical and mental health, yet the mechanisms driving this relationship remain underexplored, particularly in the United States. Using data from the 2018 General Social Survey (N = 1,045), this study examines whether time spent in natural environments mediates the relationship between access to green spaces and self‑rated physical and mental health. Linear regression models with robust standard errors reveal that time spent in natural environments mediates the relationship between access to green spaces and both health outcomes. These findings suggest that proximity to green spaces alone is insufficient to produce …
The Role Of Pten Subcellular Localization In Neuronal Development And Autism Spectrum Disorder, Nicole Desmet
The Role Of Pten Subcellular Localization In Neuronal Development And Autism Spectrum Disorder, Nicole Desmet
Dartmouth College Ph.D Dissertations
Autism spectrum disorders (ASD) are genetically heterogeneous neurodevelopmental conditions that nevertheless converge on altered neuronal connectivity and circuit function. A central unresolved problem in the field is how diverse genetic perturbations, acting at different biological levels and developmental stages, give rise to shared neurodevelopmental outcomes. This dissertation addresses this problem by examining how gene function, subcellular signaling, and developmental context interact to shape neuronal morphology and circuit-relevant phenotypes.
Cell-autonomous mechanisms regulating neuronal morphology are examined through the ASD risk gene Phosphatase and Tensin Homolog (PTEN) in developing dentate gyrus granule neurons. Selective biasing of PTEN to defined intracellular compartments in …
The Right-To-Work Debate In Louisiana: How A Moment Of Violence Changed Law, Emma K. Thigpen
The Right-To-Work Debate In Louisiana: How A Moment Of Violence Changed Law, Emma K. Thigpen
LSU Master's Theses
These two projects focus on the rise of business communities in twentieth century politics of the South and how they shaped national visions of the United States’ economic future. Chapter 1, a primary source project about how labor violence led to a Right-to-Work law, examines the actions of the La. AFL-CIO, led by Victor Bussie, and the Louisiana Association of Business and Industry, led by Edward Steimel, as they pursue alternate visions of economic progress and the “American way.” A major theme of this chapter is how violence was manipulated and refashioned to legitimize a lobbying organization and legislation intended …
Black Essential Workers Experiences With Long-Term Covid-19 Symptoms, Jeremiah Cedric Campbell
Black Essential Workers Experiences With Long-Term Covid-19 Symptoms, Jeremiah Cedric Campbell
Doctorate in Kinesiology
The purpose of this dissertation study was to understand the perceived effects of long-term COVID-19 on Black essential workers at the height of the pandemic and overall impact on mental health. The researcher interviewed 19 Black essential workers from Texas, across economic sectors (e.g., healthcare, sanitation), and who experienced long COVID symptoms. Findings centered across four themes: asking for help during the pandemic, COVID symptoms, being Black, and mental health. Using a theoretical approach incorporating critical race theory and social determinants of mental health, findings revealed the ways systemic racism affected these Black essential workers. This research can inform culturally …
The Effects Of An Eight-Week “Move Your Wayⓡ” Physical Activity Intervention On Quality Of Life And Exercise Motivation Among University Faculty Mothers, Stephanie Perez Beaudion
The Effects Of An Eight-Week “Move Your Wayⓡ” Physical Activity Intervention On Quality Of Life And Exercise Motivation Among University Faculty Mothers, Stephanie Perez Beaudion
Doctorate in Kinesiology
The purpose of this dissertation was to expand the body of knowledge on physical activity (PA) interventions and their impact on quality of life (QoL) and motivation among university faculty mothers, a population facing unique challenges in balancing professional and caregiving responsibilities. This study utilized an eight-week "Move Your WayⓇ" (MYWⓇ) PA intervention grounded in Self-Determination Theory (SDT) to explore its effects on QoL, PA levels, and exercise motivation. A total of 22 university faculty mothers participated in the study, completing pre-, mid-, and post-intervention assessments using validated tools, including the WHOQOL-BREF, IPAQ-SF, and BREQ-3. Results demonstrated statistically significant improvements …
Climate Change And Transportation, Paul J. Marchese
Climate Change And Transportation, Paul J. Marchese
Open Educational Resources
This module examines how climate change is affecting transportation systems across multiple sectors, including roads, rail, air, maritime, and active transportation. It highlights key climate trends such as rising temperatures, sea level rise, and extreme weather, and explains how these factors disrupt infrastructure, operations, and safety. The module also explores the economic, operational, and policy challenges associated with maintaining resilient transportation systems under changing environmental conditions. Finally, it presents a range of adaptation and mitigation strategies, emphasizing engineering solutions, sustainable technologies, and data-driven decision-making.
Understanding Contest Skill To Reduce The Welfare Costs Of Aggression, Lucy Oldham, Gareth Arnott, Mark Briffa, Agnieszka Futro, Jo Donbavand, Alena Kadlecova, Ali Alameer, Manzar Malik, Mhairi Jack, Iona Smith, Mark Brims, Claire Anderson, Simon P. Turner
Understanding Contest Skill To Reduce The Welfare Costs Of Aggression, Lucy Oldham, Gareth Arnott, Mark Briffa, Agnieszka Futro, Jo Donbavand, Alena Kadlecova, Ali Alameer, Manzar Malik, Mhairi Jack, Iona Smith, Mark Brims, Claire Anderson, Simon P. Turner
School of Biological and Marine Sciences
Skill is the ability to do a challenging behaviour well. We examined how contest skill influences contest success, costs and whether skilful behaviour enhances welfare. We measured skill across three domains: accuracy, appropriateness (selecting suitable agonistic tactics when the optimal choice varies) and efficiency, alongside vigour, sex and body weight. Skill was weakly correlated across domains. Winners were heavier relative to their opponent, displayed greater vigour and were more skilful at blocking, but other skill measures did not predict contest win/loss outcome. Appropriate blocking by winners reduced the number of lesions received by reducing exposure to attacks, suggesting it can …
The Role Of Avoidance In The Relationship Between The Impact Of Childhood Trauma And Physiological Responsivity To Fear And Reward In Adulthood, Tristan Alana Benjamin
The Role Of Avoidance In The Relationship Between The Impact Of Childhood Trauma And Physiological Responsivity To Fear And Reward In Adulthood, Tristan Alana Benjamin
Dissertations (1934 -)
Childhood trauma is prevalent and has been associated with deleterious physical and psychological outcomes that persist into adulthood. Extensive research on the neurobiological consequences of experiencing trauma has demonstrated an association between experiencing a traumatic event and elevated physiological arousal in response to fearful stimuli compared to healthy controls. By contrast, emerging research has found that adults who experienced a traumatic event during childhood demonstrate blunted physiological arousal responses. The physiological profile associated with childhood trauma may be related to coping strategies utilized; notably, children may be more likely to engage in avoidance to cope with the impact of trauma …
Testing A New Creighton Competency Evaluation Instrument For Pediatric Nursing, Elizabeth Anne Flasch
Testing A New Creighton Competency Evaluation Instrument For Pediatric Nursing, Elizabeth Anne Flasch
Dissertations (1934 -)
A descriptive multi-site correlational study design was used to test a modified instrument to determine its ability to assess students consistently across settings using a group of prelicensure pediatric students enrolled in two different pediatric clinical environments. Two participant groups were intentionally recruited including clinical instructors teaching in pediatric clinical environments and their corresponding students practicing in pediatric simulation and traditional clinical environments. Inter-rater reliability of the instrument was achieved. Prelicensure nursing students were deemed competent in the care of children across settings. No statistically significant correlations were found between environments. There was a relationship between student perception of confidence …
Defining Dementia: How Do We Quantify Functional Decline?, Taylor Fenderbosch, Robert Martin
Defining Dementia: How Do We Quantify Functional Decline?, Taylor Fenderbosch, Robert Martin
Advocate GME
No abstract provided.
Socially Constructing ‘Climate Change’ In Fishing Communities Of Sarangani, Philippines, Samantha Geraldine G. De Los Santos, Ma. Larissa Lelu P. Gata
Socially Constructing ‘Climate Change’ In Fishing Communities Of Sarangani, Philippines, Samantha Geraldine G. De Los Santos, Ma. Larissa Lelu P. Gata
Journal of Public Affairs and Development
The intensifying impacts of climate change have become more evident in recent years. While policies and programs have been implemented in the Philippines for decades, questions remain about how climate change is understood and experienced by fishing communities, the country’s poorest sector. By applying the Ecological-Symbolic Approach, this paper inquired into the fisherfolk’s social definition of climate change. A Qualitatively Driven Sequential Explanatory (QualDSE) mixed-methods design guided the study in developing an informed, substantiated, and context-based definition of climate change. This definition was also analyzed vis-a-vis the widely held definitions in national climate policy.
The terminology “climate change” remains unknown …
Climate-Responsive Envelope Design For Educational Buildings: A Comparative Simulation Study Between The Uk And Egypt, Hesham Safwat, Elsahamy, Elmahalawy, Samy
Climate-Responsive Envelope Design For Educational Buildings: A Comparative Simulation Study Between The Uk And Egypt, Hesham Safwat, Elsahamy, Elmahalawy, Samy
Mechanical Engineering
Educational buildings increasingly face climate-driven overheating and shifting energy demand, yet transnational campuses often replicate “home-campus” typologies without climate adaptation. This study evaluates climate-responsive envelope and HVAC strategies for a higher-education studio floor in London and office spaces in Cairo using calibrated dynamic simulations supported by in-situ monitoring with 10-minutes interval temperature and CO2 in London, short-term temperature and relative humidity in Cairo. Three scenarios were tested as follow. S01 natural ventilation; S02 mixed-mode/HVAC with existing envelope; and S03 mixed-mode/HVAC with enhanced envelope. Performance was assessed against BB101 and CIBSE TM52 overheating metrics, ISO 7730 PMV/PPD comfort indices, and CO2 …