Digital Commons Network^™

Characterization Of Circulating Extracellular Proteome In Plasma Samples Of Triple-Negative Breast Cancer Patients, Brionna Wilson

Honors Theses

Extracellular vesicles (EVs) are membrane-bound vesicles secreted by cells in the body that play an important role in intercellular signaling, immune modulation, and transfer of biomolecules between cells. EV s reflect the physiological state of their cells of origin, so they are being explored as potential noninvasive biomarkers for cancer detection and monitoring. Triple-negative breast cancer (TNBC), an aggressive subtype lacking targeted therapies, is difficult to detect early and currently has no reliable prognostic biomarkers. This study aimed to quantify EV concentrations in the blood serum of TNBC patients (n=40) compared with cancer-free healthy controls (n=35) as well as determine …

Modeling Structural Supports To Facilitate Novel Treatments Of Degenerative Disc Disease, Luis Calderon

Honors Theses

No abstract provided.

Developing A Protocol For Non-Cellular Transplantation Of Donor Mitochondria Into Recipient Cells, Andrew Parton

Honors Theses

Tumor innervation has emerged as a critical feature of cancer progression, with increased nerve density correlating with enhanced aggressiveness, metastatic dissemination, and poor clinical outcome. However, the functional contribution of neurons to tumor biology remains incompletely defined. We recently identified the intercellular transfer of mitochondria from neurons to cancer cells as a mechanism that promotes tumor progression. We therefore hypothesized that disruption of this transfer could attenuate tumor aggressivity. To directly investigate this process, we developed an approach to isolate mitochondria from donor cells and transplant them into recipient cancer cells independently of canonical cell-cell interactions. Transferred mitochondria were tracked …

Workload As A Tipping Point: A Serial Mediation Model Examining The Roles Of Job Crafting And Workload On Work Engagement, Affective Commitment, And Turnover Intentions, Jessica E. Langston

Dissertations

Job crafting is one way in which employees can boost their performance and satisfaction, and organizations can reap the benefits of high performance. Job crafting refers to an employee’s ability to proactively redesign a job to foster their satisfaction, engagement, and resilience toward work (Wrzesniewski & Dutton, 2001). After twenty-five years of study, the positive impacts of job crafting are well-established (Bhagat & Arora, 2021; Bruning & Campion, 2018; Wong et al., 2017; Wrzesniewski & Dutton, 2001). Recently scholars have noted the potential downsides and have called for more research into the nuances of job crafting when explored through the …

The Perceived Cultural Intelligence Of Leadership And Its Impact On Employee Organizational Commitment And Workplace Well-Being, Melinda Bowens

Dissertations

In today’s continuously evolving workplace, the role of leadership has expanded beyond traditional management competencies to encompass the ability to recognize, navigate, and leverage cultural differences. This quantitative study examines the relationship among perceived leader cultural intelligence, employee workplace well-being, and organizational commitment. Recognizing that workplace well-being and organizational commitment are critical to the overall health and success of organizations, it is essential to gain a greater understanding of the factors that influence these constructs. Accordingly, this study collected from 410 participants to investigate the relationship between perceived cultural intelligence of leadership, employee organizational commitment, and workplace well-being. Employing a …

Assessment Of Lake Water Quality Parameters Using Uav Hyperspectral Imaging, Hasanul Banna, Taufiqa Tajnin

Publications and Research

Monitoring water quality in lakes is critical for assessing ecosystem health, managing drinking water resources, and detecting harmful algal blooms. Unmanned Aerial Vehicle (UAV)–based hyperspectral imaging provides a promising approach for high-resolution observation of water quality parameters. In this undergraduate research project, hyperspectral imagery collected over sample lakes within the Delaware River Watershed was processed using BaySpec’s CubeStitcher software to assess its capability to detect variations in chlorophyll-a (Chl-a) concentrations. This work was conducted as part of a National Fish and Wildlife Foundation (NFWF)-funded project in collaboration with Princeton Hydro and NYC College of New York. Hyperspectral image cubes were …

Fingernail Enhancement Microbiomes Study, Kendall E. Bare

Undergraduate Honors Theses

Policies in healthcare regarding fingernail enhancements have not been supported by current science. This study examined bacterial colony growth on gel nail enhancements, regular nail polish, and bare natural nails to evaluate which condition harbors the least bacterial microbiota. The hypothesis proposed that gel enhancements would demonstrate the lowest bacterial counts compared to regular polish and unpolished nails. This investigation was conducted in the context of a local healthcare system dress code policy permitting only regular nail polish in clinical settings. Six participants volunteered and underwent nail swabbing in a microbiology laboratory using sterile cotton applicators and a neutral solution. …

Who Speaks For The Public? The Limits And Potential Of Participation In Sarasota’S Public Art, Anna Lazzara

Theses & ETDs

The City of Sarasota’s Public Art Program recently implemented a new master plan emphasizing community participation in the development of public art. This shift signals movement toward what art historian Miwon Kwon has labeled the “Art in the Public Interest” model, in which community input shapes both the process and outcome of public art. This thesis examines how the “public” is defined and represented in practice through a case study of two mural projects at the Sarasota School of Arts and Sciences: Reverend Lewis and Irene Colson (2025) and Creative Seeds (2026). Drawing on primary sources, including Public Art Committee …

Enhancing Traffic Safety Through Ai-Driven, Privacy-Preserving, And Secure Impaired Driving Detection Systems, Razan Alsulieman

Dissertations

Drunk driving remains a major threat to road safety worldwide, contributing significantly to traffic injuries and fatalities each year. Traditional detection approaches are largely reactive and vehicle-centric, relying on in-vehicle sensors, breathalyzers, or post-incident enforcement. These methods often depend on driver cooperation, intrusive hardware installations, or limited monitoring environments, restricting their scalability and effectiveness in large transportation systems. At the same time, modern cities increasingly deploy roadside cameras, surveillance networks, and drone- based monitoring systems, creating new opportunities for proactive intoxication detection at the infrastructure level. However, leveraging such external monitoring introduces challenges related to secure data collection, reliable AI-based …

Trailside Waste As An Indicator Of Human Impact: A Case Study Of The Lone Star Hiking Trail, Madison Slater

Theses & ETDs

Long-distance hiking trails provide important recreational and ecological benefits but are increasingly affected by recreation-derived waste. This study assessed the distribution and composition of litter along the 96-mile Lone Star Hiking Trail (LSHT) in the Sam Houston National Forest in the state of Texas. Using a complete trail census approach inspired by prior research on the Pacific Crest Trail (PCT), all encountered waste items were recorded, categorized, and assigned to one-mile transects to evaluate spatial patterns. A total of 327 items were documented, averaging 3.4 items per mile. Waste patterns demonstrated clear clustering near access points like that of trailheads …

Why Has There Been A Drought In The Ipo Market?, Hannah Picott

Theses & ETDs

In recent years, initial public offerings have seen a decline in volume that historically should not have taken place. The economic conditions have indicated a strong initial public offerings market; however, this has not been seen. Research has shown that there has been a rise in alternatives to entering the public market and a lengthened timeline of companies remaining private. In this study, data on the volume of initial public offerings, P/E ratios, and private equity have been used in tandem with charts and a regression to analyze the potential diminishing of IPOs. Finance is forever evolving; what is known …

Return Of The Wolf: An Assessment Of The Reintroduction Of The Gray Wolves To Yellowstone National Park, Keagan Roeder

Theses & ETDs

This paper examines the reintroduction of gray wolves to Yellowstone National Park by breaking the topic into several sections. It begins with an introduction and a history and timeline section, which provide background on wolf eradication and the events leading up to their reintroduction in 1995–1996. The paper then moves into legal sections, including discussions of the Endangered Species Act, the Environmental Impact Statement, and key court cases, explaining how policy and law made the reintroduction possible and continue to shape wolf management. Ecological impacts are explored in sections focused on animal populations and behavior, waterways, and plant communities, highlighting …

From The Field To The Sidelines: Student-Athletes’ Transitions Into Coaching, Lais Leonardo Martins

Theses & ETDs

This study explores the transition from student-athlete to coach and examines how athletic experiences shape individuals’ motivations, leadership philosophies, and identity development. Drawing on qualitative data from semi-structured interviews with current and former student-athletes, as well as the researcher’s own experience, this research analyzes how individuals navigate the shift from competitive sport to leadership roles. The findings highlight the central role of athletic identity in shaping the transition process, as many participants experienced challenges redefining their sense of purpose after leaving competition. Coaching emerged as a key pathway that allows former athletes to maintain their connection to sport while transforming …

Understanding Tlr3 Immune Response Activation In Cryptosporidium Parvum And Cryspovirus Pathogenesis, Surayya Hudayberganova

Biochemistry and Molecular Biology

Cryptosporidiosis is a serious gastrointestinal illness caused by a protozoan parasite known as Cryptosporidium. It is particularly dangerous for malnourished children and those with compromised immune systems. My research focuses on the Toll-like receptor 3 (TLR3) response to the Cryptosporidium parvum infection, specifically in the presence of the parasite’s viral mutualist named cryspovirus (CSpV1). Results using research methodologies like ELISA and RT-qPCR have indicated that TLR3 expression increases during the infection process of Cryptosporidium parvum (C. parvum). Furthermore, one intriguing observation concluded during this study suggests that administering the TLR3-specific inhibitor CU-CPT4a to infected cells drastically decreased this activation. This …

A Comprehensive Look At Gaps And Needs In Resources And Services For The Unhoused In Four Counties In Midcoast Maine., Emily Carroll Ma

All Student Scholarship

Homelessness represents a significant public health concern affecting communities across the nation.  This matter requires society’s focus on cities because it is visible to all and represents an obvious public health concern. However, Homelessness is not limited to cities; it impacts people from varied backgrounds and exists as much in rural areas as in urban areas.   Rural homelessness remains insufficiently researched and is frequently misunderstood.  This project looks at one geographic location on the Coast of Maine and assesses the specific barriers and service gaps within this region.

Effects Of Early Life Karenia Brevis Exposure On Bottlenose Dolphin Calves In Sarasota Bay, Florida, Elizabeth Fry

Theses & ETDs

Harmful Algal Blooms (HABs) have increased in frequency, intensity and geographic distribution in the past several decades. Florida is an epicenter for an HAB, commonly referred to as red tide, caused by the algal dinoflagellate Karenia brevis, which produces the neurotoxin brevetoxin. Acute exposure to brevetoxin causes respiratory distress and has been associated with large scale marine mammal mortalities and fish kills. However, potential chronic effects of exposure, including via maternal transfer, have not been well characterized. Fetal and juvenile mammals may be particularly susceptible to the neurobiological effects of excitotoxins due to their developmental stage. Many resident coastal bottlenose …

Inbreeding Effects On Fitness-Related Traits: Evidence From Two Populations Of The Least Killifish (Heterandria Formosa), Abigail Hansen

Theses & ETDs

Inbreeding, the mating of closely related individuals, can affect the fitness and overall health of natural populations by reducing genetic diversity and exposing deleterious recessive alleles. To better understand the effects of inbreeding, a controlled lab experiment was conducted using the Least Killifish species, Heterandria Formosa. Many species have evolved behavioral and demographic mechanisms to avoid inbreeding; however, these mechanisms can be constrained in small or structured populations. This species was purposely chosen for this experiment as the fish appear in two diverse populations; a population with high density from the Wacissa River (WR) located in South-Central Jefferson county, Florida …

Honduras’ Stagnant Development: An Institutional And Solow Growth Analysis From 1990-2022, Alejandra Martinez

Theses & ETDs

For the past 33 years, Honduras has been persistently one of the poorest Latin American countries, classified as a lower-middle income country with high crime rates and political corruption. Honduras, like other Latin American countries, is known for being rich in natural resources, but despite over 60 years of foreign aid has yet to develop itself domestically and internationally, as Western standard deems it. Previous research on Honduras’ poverty and economic development are typically centered around a specific region and the rural sector, but there is a gap in the literature that analyzes the economic disparity of the country as …

Pro Rege Chr. Brass Band: A Century Of Sound, Jonathan T.J. Henneveld

Dissertations

The Christian Brass Band Pro Rege of Heerenveen, The Netherlands, celebrated its one hundredth birthday in 2024. As one of the most prominent community-based brass bands in the region, Pro Rege is part of a Dutch wind ensemble tradition that goes largely undocumented. While they and other bands like them function as cultural and educational institutions, academic literature remains limited, almost ignoring them completely. This dissertation wishes to address this oversight by providing an historical study of the brass band from its establishment in 1924 to the present day.

Starting out in the Dutch ensemble tradition of the Fanfare band, …

Sustainability Savvy: The Role Of Competence And Efficacy In Promoting Pro-Environmental Behavior, Lorenna Graham

Environmental Studies Honors Projects

Combatting environmental issues requires both large-scale and individual change. While many understand that personal pro-environmental behavior (PEB) is necessary, individuals do not always engage in this behavior (Hines, 1986, Goh, 2022). Thus, there is a need to investigate psychological factors which encourage PEB. Prior research suggests competence and outcome efficacy as likely PEB predictors (Bentler, 2023, Lavergne & Pelletier, 2015, Priolo, 2016), while cognitive dissonance has been shown to both encourage and discourage PEB (Bouwman, 2022, Dickerson, 1992, Ehrich & Irwin, 2005). Study 1 investigates the relationship between cognitive dissonance and PEB with competence and outcome efficacy as potential moderators. …

Mckee Minute May 2026, Southern Adventist University

McKee Minute – McKee Library This Month

The May 2026 edition of McKee Minute includes information on end of semester deadlines, Campus Research Month, the library's summer hours, Mental Health Awareness month, and summer reading with Libby.

Complete Issue - Spring 2026

The Prairie Light Review

No abstract provided.

Social Protection To Foster Inclusive, Resilient Early Childhood Education In Kenya, Uganda, And Tanzania, Nyagwegwe Wango

Institute for Educational Development, East Africa

In order to evaluate the efficacy of systems approaches in enhancing early childhood education (ECE), this study summarizes outcomes from the SESEA and F4L programs in Kenya, Tanzania, and Uganda. The study investigates how context-responsive ECE, social-emotional learning (SEL), and social protection (SP) interventions contribute to improvements in teaching practices, inclusion, and learner outcomes using mixed-methods data, including teacher surveys, classroom observations, and policy analysis. The findings show significant improvements in inclusive classroom practices, gender-sensitive pedagogy, and teacher confidence, especially when reflective peer learning and continuous mentoring are incorporated. Children’s academic performance and well-being have been linked to the integration …

Changes In The Dental & Oral Health Information Landscape, Alisun Dekock, Melissa Ernst, Jimmy Gonzalez Vicker, Kelly O'Brien

Individual Scholarship

As we navigate rapid changes to information access and utilization, dental and oral health care professionals are finding new ways to meet the needs of their users. Practitioners locating, evaluating, and applying research continues to encounter new obstacles, including significant changes to institutions that share health data and make recommendations. This poster discusses effective strategies dentistry librarians have used for information retrieval, method analysis, and patient education.

Background  

This poster provides an overview of how four dentistry librarians are responding to trends and changes in the dental and oral health information landscape at their various institutions and organizations.

Description   

Within …

Ai Literacy In The Nursing Informatics Community: A Needs Assessment, Jerri Westphal

Doctoral Projects

Nursing informatics professionals are required to lead AI integration in healthcare, yet their baseline AI literacy, competency, and educational needs have not been formally assessed. This descriptive needs assessment examined AI literacy, competency, adoption readiness, and engagement among nursing informatics professionals, concurrently identifying educational priorities and preferred learning modalities. A cross-sectional survey was administered to members of the American Nursing Informatics Association (ANIA) and the broader community (N = 194). The N.U.R.S.E.S. framework (Hoelscher & Pugh, 2025) informed the survey instrument's domain structure. Five composite indices were developed: AI Familiarity, Knowledge, Attitude, Competency, and Use. Descriptive statistics and Pearson correlation …

Wanti Wanti Nuh Ghetti: Navigating The American Theatre Through A Multicultural Lens, Gabriela Madu

Graduate Theses and Dissertations

This thesis explores how actors of color navigate educational and professional spaces so they can bring their full experiences to the projects they take on, whether those projects are written for them or not. Through the depiction of the struggles faced by women of color in educational theatre in my one-person show Wanti Wanti Nuh Ghetti, the thesis argues that theatre holds transformative potential when actors of color are not merely visible on stage, but are deeply invested in their work and have a sense of belonging within the creative process. Drawing on this performance, the study further explores how …

"Shhh": A Reflection On Matrescence, Anna Guillory

Graduate Theses and Dissertations

“Shhh” is a collection of drawings that reflect on the many ways the first year of motherhood shifts identity, perspective, and relationships. Focusing on my personal experience of becoming a caregiver, each work acts as an exploration and artifact of the shared labor between parenting and redeveloping an art practice, articulating both the tension and the enmeshing of these two realities. The work poses questions around value and production and consequently presents considerations of the passage into matrescence itself. Through a combination of rendered images, gestures and marks from observed moments in domestic space, postpartum life, and my own inner, …

A Multi-Criteria Decision And Spatial Modeling Framework For Socially Informed Advanced Air Mobility Implementation Planning, Noah Wesley Bretz

Graduate Theses and Dissertations

Advanced air mobility (AAM) is an emerging mode of transportation that integrates advanced aircraft technologies, such as manned air taxis or unmanned freight drones, to transport people and goods across urban and regional environments. While these technologies promise to transform mobility, successful implementation depends heavily on community acceptance, which is shaped by multiple social factors. This study presents a multi-criteria decision framework to evaluate and prioritize the key social factors influencing AAM adoption. A literature review identified six primary social factors: safety, noise, privacy and cybersecurity, automation, environmental impact, and price and economics. The Analytical Hierarchy Process (AHP) was used …

May 2026 News You Need, David Foe

The Journal of the Michigan Dental Association

This source provides comprehensive updates on organized dentistry, including the appointment of Dr. Nader A. Nadershahi as the new ADA executive director. It reports on the MDA's current membership market share, which remains high at approximately 70% despite national trends. Significant health topics covered include Mental Health Awareness Month resources like the Well-Being Index and a patient fact sheet linking oral health to systemic conditions like heart disease and diabetes.

Mda At Your Service: What Are The New Features On The Mda Member Compass?, Rachel Sinacola Dds, Ms

The Journal of the Michigan Dental Association

This Q&A column assists members in utilizing association resources. It highlights the new MDA Member Compass, which allows for online practice management, staff roster updates, and event registration. It also offers critical advice for new graduates regarding state licensure, mandatory insurance policies, and contract review services. Furthermore, it describes the MDA Peer Review System, a confidential process for resolving patient-dentist disputes through impartial committee evaluation rather than litigation.