Digital Commons Network^™

Evaluation Of The Effectiveness Of Antihypertensive Therapy Chosen Through Maternal Hemodynamic Profile Analysis, Margaret Weimer

Honors Theses

Medication choice is tightly regulated in most situations, but in the field of obstetric medicine, the American College of Obstetricians and Gynecologists (ACOG) recommends both labetalol and nifedipine as oral treatments for emergent hypertension, with no preference shown between the two. Studies have suggested that consideration of hemodynamic profile may be an effective way to determine medication, but have not considered the Rule of 55, a simple calculation to predict hemodynamic profile. The goals of this study were to determine whether tailoring the oral hypertensive medication to a patient’s hemodynamic profile is associated with better blood pressure control within 72 …

Acute Effects Of The Psychoactive Pollutant Fluoxetine On The Antipredator Behavior Of The Gulf Killifish (Fundulus Grandis), Semyra Reus

Honors Theses

Pharmaceutical contaminants are increasingly prevalent in aquatic environments, yet their sublethal effects on ecologically relevant behaviors remain poorly understood, particularly in estuarine systems. Selective serotonin reuptake inhibitors (SSRIs), such as fluoxetine, are of particular concern due to the conserved role of serotonin in regulating behavior across vertebrates. Here, we investigated how acute exposure to environmentally relevant concentrations of fluoxetine influences anti-predator behavior in Gulf killifish (Fundulus grandis), a key estuarine fish commonly found in saltmarsh habitats. Killifish were exposed to control (0 ng/L), low (17.8 ng/L), and high (596 ng/L) fluoxetine concentrations and subsequently tested in the presence …

Choosing Death: The Moral Legitimacy Of Voluntary Active Euthanasia, Emma Rougeou

Honors Theses

During the last three decades, the issue of physician assisted suicide has captivated the interest of private citizens and state legislatures. Thinking about the matter of end-of-life concerns, particularly surrounding euthanasian (practices that hasten the deaths of suffering terminally ill people) have shifted. Views of private citizens and state-level legislation reflects a “slow shift to more permissive attitudes” (Cohen et al., 2012). Meanwhile, as recently as March 2026, state legislators in conjunction with the NY State Governor, passed a bill legalizing medical aid in dying for terminally ill patients. This thesis is intended to thoughtfully contribute to meaningful discourse on …

Navigating The Nicu Without Words: A Case Study Of A Spanish-Speaking Mother’S Healthcare Experience, Emma Norris

Honors Theses

Background: Few studies examine language barriers in the neonatal intensive care unit (NICU). Miscommunication and lack of understanding between the healthcare team and a NICU infant’s parents may easily occur when the relationship is inhibited by a language barrier. Previous studies show that a lack of parent-provider communication creates additional anxiety for parents. The purpose of this study is to explore and describe the experiences and barriers in communication between an English-speaking nurse, an English-Spanish bilingual nurse, and a Spanish-speaking mother of a NICU infant.

Methods: This project was a case study using an exploratory mixed methods qualitative design. Qualitative …

Urea-Based Boronium Salts As Antimicrobial Agents, Gabriel Allen Merchant

Honors Theses

Quaternary ammonium compounds (QACs) are widely used in disinfectants due to their ability to inhibit the growth of and eliminate microbes. The potency, broad-spectrum activity, and low cost of QACs have made them a cornerstone of modem hygiene. In recent years, QACs have garnered many health and safety concerns due to their overuse and subsequent accumulation in the environment. The increased use of QACs has further led to an increase in antimicrobial-resistant bacteria, making the synthesis of novel antibacterial compounds vital to combat this growing threat. Recent advances in boronium salts offer a unique alternative to address these adverse effects. …

Community Perceptions Of A Hospital-Based Doula Program In Mobile, Alabama, Sarah Laney

Honors Theses

Background: The maternal mortality ratio in the United States is much higher than the mortality rate for women who live in other countries with similar Human Development Index scores. Black women are more likely to die than their white counterparts. Most of these deaths are preventable. Patients feel like they are being ignored, or that they are not being seen. Doula care is a possible solution to these problems.

Purpose: The purpose of this study was to assess patient understanding and perception of doulas as well as comparing desire for doulas to demographics and past experiences to search for relationships. …

Spectral Characterization Of Colorectal Cancer Using Excitation-Scanning Hyperspectral Imaging, Natalie Hadad

Honors Theses

Colorectal cancer is one of the most common and deadly cancers worldwide, with a lifetime risk of approximately one in twenty-three for men and one in twenty-five for women. Although early detection significantly improves survival, current diagnostic approaches such as tissue biopsy are invasive, reliant on subjective interpretation, have extended turnaround times, and risk missing flat or depressed lesions that are more difficult to detect than raised polyps. These limitations highlight the need for objective, minimally invasive technologies capable of detecting early tissue changes. This study investigates excitation-scanning hyperspectral imaging (Ex-HSI) as a label-free optical approach for identifying colorectal cancer–associated …

Novel Biomarker Discovery In Multiple Sclerosis, Manisha Gangasani

Honors Theses

Multiple Sclerosis (MS) is a chronic neuroinflammatory disorder affecting the brain, spinal cord, and optic nerve. Patients experience cognitive, motor, autonomic, and emotional symptoms that often overlap with other neurological conditions, making early diagnosis challenging. Current diagnostic criteria require evidence of lesions with dissemination in time and space. Racial disparities in MS outcomes are well documented, with Black individuals often exhibiting greater disease severity, higher relapse rates, and increased disability compared to White individuals. These differences likely reflect a combination of genetic, biological, environmental, and healthcare access factors, underscoring the need to improve early diagnosis and reduce inequities in care. …

Characterization Of Circulating Extracellular Proteome In Plasma Samples Of Triple-Negative Breast Cancer Patients, Brionna Wilson

Honors Theses

Extracellular vesicles (EVs) are membrane-bound vesicles secreted by cells in the body that play an important role in intercellular signaling, immune modulation, and transfer of biomolecules between cells. EV s reflect the physiological state of their cells of origin, so they are being explored as potential noninvasive biomarkers for cancer detection and monitoring. Triple-negative breast cancer (TNBC), an aggressive subtype lacking targeted therapies, is difficult to detect early and currently has no reliable prognostic biomarkers. This study aimed to quantify EV concentrations in the blood serum of TNBC patients (n=40) compared with cancer-free healthy controls (n=35) as well as determine …

Modeling Structural Supports To Facilitate Novel Treatments Of Degenerative Disc Disease, Luis Calderon

Honors Theses

No abstract provided.

Developing A Protocol For Non-Cellular Transplantation Of Donor Mitochondria Into Recipient Cells, Andrew Parton

Honors Theses

Tumor innervation has emerged as a critical feature of cancer progression, with increased nerve density correlating with enhanced aggressiveness, metastatic dissemination, and poor clinical outcome. However, the functional contribution of neurons to tumor biology remains incompletely defined. We recently identified the intercellular transfer of mitochondria from neurons to cancer cells as a mechanism that promotes tumor progression. We therefore hypothesized that disruption of this transfer could attenuate tumor aggressivity. To directly investigate this process, we developed an approach to isolate mitochondria from donor cells and transplant them into recipient cancer cells independently of canonical cell-cell interactions. Transferred mitochondria were tracked …

Workload As A Tipping Point: A Serial Mediation Model Examining The Roles Of Job Crafting And Workload On Work Engagement, Affective Commitment, And Turnover Intentions, Jessica E. Langston

Dissertations

Job crafting is one way in which employees can boost their performance and satisfaction, and organizations can reap the benefits of high performance. Job crafting refers to an employee’s ability to proactively redesign a job to foster their satisfaction, engagement, and resilience toward work (Wrzesniewski & Dutton, 2001). After twenty-five years of study, the positive impacts of job crafting are well-established (Bhagat & Arora, 2021; Bruning & Campion, 2018; Wong et al., 2017; Wrzesniewski & Dutton, 2001). Recently scholars have noted the potential downsides and have called for more research into the nuances of job crafting when explored through the …

The Perceived Cultural Intelligence Of Leadership And Its Impact On Employee Organizational Commitment And Workplace Well-Being, Melinda Bowens

Dissertations

In today’s continuously evolving workplace, the role of leadership has expanded beyond traditional management competencies to encompass the ability to recognize, navigate, and leverage cultural differences. This quantitative study examines the relationship among perceived leader cultural intelligence, employee workplace well-being, and organizational commitment. Recognizing that workplace well-being and organizational commitment are critical to the overall health and success of organizations, it is essential to gain a greater understanding of the factors that influence these constructs. Accordingly, this study collected from 410 participants to investigate the relationship between perceived cultural intelligence of leadership, employee organizational commitment, and workplace well-being. Employing a …

Assessment Of Lake Water Quality Parameters Using Uav Hyperspectral Imaging, Hasanul Banna, Taufiqa Tajnin

Publications and Research

Monitoring water quality in lakes is critical for assessing ecosystem health, managing drinking water resources, and detecting harmful algal blooms. Unmanned Aerial Vehicle (UAV)–based hyperspectral imaging provides a promising approach for high-resolution observation of water quality parameters. In this undergraduate research project, hyperspectral imagery collected over sample lakes within the Delaware River Watershed was processed using BaySpec’s CubeStitcher software to assess its capability to detect variations in chlorophyll-a (Chl-a) concentrations. This work was conducted as part of a National Fish and Wildlife Foundation (NFWF)-funded project in collaboration with Princeton Hydro and NYC College of New York. Hyperspectral image cubes were …

Fingernail Enhancement Microbiomes Study, Kendall E. Bare

Undergraduate Honors Theses

Policies in healthcare regarding fingernail enhancements have not been supported by current science. This study examined bacterial colony growth on gel nail enhancements, regular nail polish, and bare natural nails to evaluate which condition harbors the least bacterial microbiota. The hypothesis proposed that gel enhancements would demonstrate the lowest bacterial counts compared to regular polish and unpolished nails. This investigation was conducted in the context of a local healthcare system dress code policy permitting only regular nail polish in clinical settings. Six participants volunteered and underwent nail swabbing in a microbiology laboratory using sterile cotton applicators and a neutral solution. …

Who Speaks For The Public? The Limits And Potential Of Participation In Sarasota’S Public Art, Anna Lazzara

Theses & ETDs

The City of Sarasota’s Public Art Program recently implemented a new master plan emphasizing community participation in the development of public art. This shift signals movement toward what art historian Miwon Kwon has labeled the “Art in the Public Interest” model, in which community input shapes both the process and outcome of public art. This thesis examines how the “public” is defined and represented in practice through a case study of two mural projects at the Sarasota School of Arts and Sciences: Reverend Lewis and Irene Colson (2025) and Creative Seeds (2026). Drawing on primary sources, including Public Art Committee …

Enhancing Traffic Safety Through Ai-Driven, Privacy-Preserving, And Secure Impaired Driving Detection Systems, Razan Alsulieman

Dissertations

Drunk driving remains a major threat to road safety worldwide, contributing significantly to traffic injuries and fatalities each year. Traditional detection approaches are largely reactive and vehicle-centric, relying on in-vehicle sensors, breathalyzers, or post-incident enforcement. These methods often depend on driver cooperation, intrusive hardware installations, or limited monitoring environments, restricting their scalability and effectiveness in large transportation systems. At the same time, modern cities increasingly deploy roadside cameras, surveillance networks, and drone- based monitoring systems, creating new opportunities for proactive intoxication detection at the infrastructure level. However, leveraging such external monitoring introduces challenges related to secure data collection, reliable AI-based …

Trailside Waste As An Indicator Of Human Impact: A Case Study Of The Lone Star Hiking Trail, Madison Slater

Theses & ETDs

Long-distance hiking trails provide important recreational and ecological benefits but are increasingly affected by recreation-derived waste. This study assessed the distribution and composition of litter along the 96-mile Lone Star Hiking Trail (LSHT) in the Sam Houston National Forest in the state of Texas. Using a complete trail census approach inspired by prior research on the Pacific Crest Trail (PCT), all encountered waste items were recorded, categorized, and assigned to one-mile transects to evaluate spatial patterns. A total of 327 items were documented, averaging 3.4 items per mile. Waste patterns demonstrated clear clustering near access points like that of trailheads …

Why Has There Been A Drought In The Ipo Market?, Hannah Picott

Theses & ETDs

In recent years, initial public offerings have seen a decline in volume that historically should not have taken place. The economic conditions have indicated a strong initial public offerings market; however, this has not been seen. Research has shown that there has been a rise in alternatives to entering the public market and a lengthened timeline of companies remaining private. In this study, data on the volume of initial public offerings, P/E ratios, and private equity have been used in tandem with charts and a regression to analyze the potential diminishing of IPOs. Finance is forever evolving; what is known …

Return Of The Wolf: An Assessment Of The Reintroduction Of The Gray Wolves To Yellowstone National Park, Keagan Roeder

Theses & ETDs

This paper examines the reintroduction of gray wolves to Yellowstone National Park by breaking the topic into several sections. It begins with an introduction and a history and timeline section, which provide background on wolf eradication and the events leading up to their reintroduction in 1995–1996. The paper then moves into legal sections, including discussions of the Endangered Species Act, the Environmental Impact Statement, and key court cases, explaining how policy and law made the reintroduction possible and continue to shape wolf management. Ecological impacts are explored in sections focused on animal populations and behavior, waterways, and plant communities, highlighting …

From The Field To The Sidelines: Student-Athletes’ Transitions Into Coaching, Lais Leonardo Martins

Theses & ETDs

This study explores the transition from student-athlete to coach and examines how athletic experiences shape individuals’ motivations, leadership philosophies, and identity development. Drawing on qualitative data from semi-structured interviews with current and former student-athletes, as well as the researcher’s own experience, this research analyzes how individuals navigate the shift from competitive sport to leadership roles. The findings highlight the central role of athletic identity in shaping the transition process, as many participants experienced challenges redefining their sense of purpose after leaving competition. Coaching emerged as a key pathway that allows former athletes to maintain their connection to sport while transforming …

Understanding Tlr3 Immune Response Activation In Cryptosporidium Parvum And Cryspovirus Pathogenesis, Surayya Hudayberganova

Biochemistry and Molecular Biology

Cryptosporidiosis is a serious gastrointestinal illness caused by a protozoan parasite known as Cryptosporidium. It is particularly dangerous for malnourished children and those with compromised immune systems. My research focuses on the Toll-like receptor 3 (TLR3) response to the Cryptosporidium parvum infection, specifically in the presence of the parasite’s viral mutualist named cryspovirus (CSpV1). Results using research methodologies like ELISA and RT-qPCR have indicated that TLR3 expression increases during the infection process of Cryptosporidium parvum (C. parvum). Furthermore, one intriguing observation concluded during this study suggests that administering the TLR3-specific inhibitor CU-CPT4a to infected cells drastically decreased this activation. This …

A Comprehensive Look At Gaps And Needs In Resources And Services For The Unhoused In Four Counties In Midcoast Maine., Emily Carroll Ma

All Student Scholarship

Homelessness represents a significant public health concern affecting communities across the nation.  This matter requires society’s focus on cities because it is visible to all and represents an obvious public health concern. However, Homelessness is not limited to cities; it impacts people from varied backgrounds and exists as much in rural areas as in urban areas.   Rural homelessness remains insufficiently researched and is frequently misunderstood.  This project looks at one geographic location on the Coast of Maine and assesses the specific barriers and service gaps within this region.

Effects Of Early Life Karenia Brevis Exposure On Bottlenose Dolphin Calves In Sarasota Bay, Florida, Elizabeth Fry

Theses & ETDs

Harmful Algal Blooms (HABs) have increased in frequency, intensity and geographic distribution in the past several decades. Florida is an epicenter for an HAB, commonly referred to as red tide, caused by the algal dinoflagellate Karenia brevis, which produces the neurotoxin brevetoxin. Acute exposure to brevetoxin causes respiratory distress and has been associated with large scale marine mammal mortalities and fish kills. However, potential chronic effects of exposure, including via maternal transfer, have not been well characterized. Fetal and juvenile mammals may be particularly susceptible to the neurobiological effects of excitotoxins due to their developmental stage. Many resident coastal bottlenose …

Inbreeding Effects On Fitness-Related Traits: Evidence From Two Populations Of The Least Killifish (Heterandria Formosa), Abigail Hansen

Theses & ETDs

Inbreeding, the mating of closely related individuals, can affect the fitness and overall health of natural populations by reducing genetic diversity and exposing deleterious recessive alleles. To better understand the effects of inbreeding, a controlled lab experiment was conducted using the Least Killifish species, Heterandria Formosa. Many species have evolved behavioral and demographic mechanisms to avoid inbreeding; however, these mechanisms can be constrained in small or structured populations. This species was purposely chosen for this experiment as the fish appear in two diverse populations; a population with high density from the Wacissa River (WR) located in South-Central Jefferson county, Florida …

Honduras’ Stagnant Development: An Institutional And Solow Growth Analysis From 1990-2022, Alejandra Martinez

Theses & ETDs

For the past 33 years, Honduras has been persistently one of the poorest Latin American countries, classified as a lower-middle income country with high crime rates and political corruption. Honduras, like other Latin American countries, is known for being rich in natural resources, but despite over 60 years of foreign aid has yet to develop itself domestically and internationally, as Western standard deems it. Previous research on Honduras’ poverty and economic development are typically centered around a specific region and the rural sector, but there is a gap in the literature that analyzes the economic disparity of the country as …

Pro Rege Chr. Brass Band: A Century Of Sound, Jonathan T.J. Henneveld

Dissertations

The Christian Brass Band Pro Rege of Heerenveen, The Netherlands, celebrated its one hundredth birthday in 2024. As one of the most prominent community-based brass bands in the region, Pro Rege is part of a Dutch wind ensemble tradition that goes largely undocumented. While they and other bands like them function as cultural and educational institutions, academic literature remains limited, almost ignoring them completely. This dissertation wishes to address this oversight by providing an historical study of the brass band from its establishment in 1924 to the present day.

Starting out in the Dutch ensemble tradition of the Fanfare band, …

Sustainability Savvy: The Role Of Competence And Efficacy In Promoting Pro-Environmental Behavior, Lorenna Graham

Environmental Studies Honors Projects

Combatting environmental issues requires both large-scale and individual change. While many understand that personal pro-environmental behavior (PEB) is necessary, individuals do not always engage in this behavior (Hines, 1986, Goh, 2022). Thus, there is a need to investigate psychological factors which encourage PEB. Prior research suggests competence and outcome efficacy as likely PEB predictors (Bentler, 2023, Lavergne & Pelletier, 2015, Priolo, 2016), while cognitive dissonance has been shown to both encourage and discourage PEB (Bouwman, 2022, Dickerson, 1992, Ehrich & Irwin, 2005). Study 1 investigates the relationship between cognitive dissonance and PEB with competence and outcome efficacy as potential moderators. …

Mckee Minute May 2026, Southern Adventist University

McKee Minute – McKee Library This Month

The May 2026 edition of McKee Minute includes information on end of semester deadlines, Campus Research Month, the library's summer hours, Mental Health Awareness month, and summer reading with Libby.

Complete Issue - Spring 2026

The Prairie Light Review

No abstract provided.