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Poor Oral Health Is Associated With Inflammation, Aortic Valve Calcification, And Brain Volume Among Forager-Farmers, Benjamin C. Trumble, Matthew Schwartz, Andrew T. Ozga, Gary T. Schwartz, Christopher M. Stojanowski, Carrie L. Jenkins, Thomas Kraft, Angela R. Garcia, Daniel K. Cummings, Paul L. Hooper, Daniel Eid Rodriguez, Kenneth Buetow, Bret Beheim, Andrei Irimia, Gregory S. Thomas, Randall C. Thompson, Horus Team, Margaret Gatz, Jonathan Stieglitz, Caleb E. Finch, Michael Gurven, Hillard Kaplan Jan 2024

Poor Oral Health Is Associated With Inflammation, Aortic Valve Calcification, And Brain Volume Among Forager-Farmers, Benjamin C. Trumble, Matthew Schwartz, Andrew T. Ozga, Gary T. Schwartz, Christopher M. Stojanowski, Carrie L. Jenkins, Thomas Kraft, Angela R. Garcia, Daniel K. Cummings, Paul L. Hooper, Daniel Eid Rodriguez, Kenneth Buetow, Bret Beheim, Andrei Irimia, Gregory S. Thomas, Randall C. Thompson, Horus Team, Margaret Gatz, Jonathan Stieglitz, Caleb E. Finch, Michael Gurven, Hillard Kaplan

ESI Publications

Poor oral health is associated with cardiovascular disease and dementia. Potential pathways include sepsis from oral bacteria, systemic inflammation, and nutritional deficiencies. However, in post-industrialized populations, links between oral health and chronic disease may be confounded because the lower socioeconomic exposome (poor diet, pollution, low physical activity) often entails insufficient dental care. We assessed tooth loss, caries, and damaged teeth, in relation to cardiovascular and brain aging among the Tsimane, a subsistence population living a relatively traditional forager-horticulturalist lifestyle with poor dental health, but minimal cardiovascular disease and dementia. Dental health was assessed by a physician in 739 participants aged …


Prevention Of Food Fraud In Egypt: Policy Implementation Challenges And The Way Forward, Hager Yehia Shalaby Jan 2024

Prevention Of Food Fraud In Egypt: Policy Implementation Challenges And The Way Forward, Hager Yehia Shalaby

Theses and Dissertations

Prevention and control of food fraud is now an emerging policy goal for different governments. Food fraud is intentionally adulterating food intended for personal gain and deceiving consumers. Adulterated food continues to be a significant threat to Egypt's food sector because of its negative impact on the food industry's reputation. Additionally, it jeopardizes the success of initiatives to increase investment, tourism, and exports in Egypt. Addressing fraud is, by definition, the most challenging food control system form because it directly addresses a personal stake benefiting from fraud behavior. In light of the importance of food fraud prevention as an emerging …


Reliable Outdoor Ai-Based Autonomous Uav Localization And Trajectory Tracking Using Cellular Networks, Ghada Afifi Jan 2024

Reliable Outdoor Ai-Based Autonomous Uav Localization And Trajectory Tracking Using Cellular Networks, Ghada Afifi

Theses and Dissertations

Unmanned aerial vehicles (UAVs) are becoming an integral part of numerous commercial and military applications. In many of these applications, the UAV is required to self-navigate in highly dynamic urban environments. Existing localization and trajectory planning techniques, which rely mainly on the Global Positioning System (GPS), do not provide an effective real-time solution for self-localization and path planning, particularly in dense urban environments. The purpose of this thesis is to study the localization and trajectory planning of UAVs independent of GPS systems or other detectable mobile signals. We propose to utilize the broadcast signals from existing cellular networks to localize …


The Effect Of Esg On Indices’ And Firms’ Performance. A Global And An Egyptian Context., Demiana Abdelmalak Jan 2024

The Effect Of Esg On Indices’ And Firms’ Performance. A Global And An Egyptian Context., Demiana Abdelmalak

Theses and Dissertations

Over the years, ESG (environmental, social, and governance) investing has been increasingly adopted by the financial markets. In this paper, we aim to study the effect of ESG on Indices’ and Firms’ performance using Morgan Stanley Capital International (MSCI) Indices as a global reference and Egypt’s indices as a national reference. We also study the effect of ESG scores on the Egyptian Firms’ performance over the past 16 years using econometrical models and Fama- French Five Factors Model. Our research shows mixed results which are aligned with the existing literature review. However, one can conclude that there is a positive …


Investigating The Association Between Gut Bacteria And Childhood Neuropsychiatric Disorders, Maha Abdo Jan 2024

Investigating The Association Between Gut Bacteria And Childhood Neuropsychiatric Disorders, Maha Abdo

Theses and Dissertations

Background: The etiology of autism spectrum disorder (ASD) remains unclear. However, it’s believed to be a multifactorial condition. Several studies suggest the involvement of gut and oral microbiome in the predisposition of ASD symptoms. Understanding the pathophysiology could aid in developing better treatment strategies that improve the quality of life of ASD individuals and their caregivers.

Aim: The current study aims at characterizing the gut and oral microbiome composition of ASD children compared to their healthy siblings and mothers as control groups.

Methods: Stool and saliva samples were collected from fourteen families at Ain Shams University Hospital, Outpatient Clinic. The …


The Brain Drain Of The Egyptian Physicians: A Look From Both Sides, Hebatalla Ahmed Mohamed Ismail Jan 2024

The Brain Drain Of The Egyptian Physicians: A Look From Both Sides, Hebatalla Ahmed Mohamed Ismail

Theses and Dissertations

The brain drain of well-educated and trained workers is a problem that faces many nations. The pandemic revealed the importance of being ready with all resources, especially the healthcare workers. In Egypt, according to records of the Egyptian medical syndicate, half of the registered physicians in the syndicate are working abroad. In this study, we aimed to understand the relationship between individual satisfaction regarding work or family, his capability factors, and his intention to leave the country to work in another one. A quantitative approach was used by a self-administered online questionnaire. The results showed that 66.4% of physicians who …


Antibacterial And Anticancer Activities Of A Fosmid Clone From Atlantis Ii Red Sea Brine Pool., Marina Nabil Jan 2024

Antibacterial And Anticancer Activities Of A Fosmid Clone From Atlantis Ii Red Sea Brine Pool., Marina Nabil

Theses and Dissertations

Antimicrobial resistance (AMR) and cancer are among the top global human health issues requiring urgent control practices. AMR caused 5 million death cases around the world in 2019. This number is expected to reach 10 million deaths by 2050. Cancer deaths reached 10 million in 2020. Additionally, anticancer drug resistance is a common cause of death among cancer patients. Screening for novel compounds is one of the strategies recommended by the World Health Organization (WHO) to control drug resistance in microbial and cancer cells. Marine natural products (MNPs) are characterized by chemically diverse structures with various bioactivities, especially in extreme …


Blooming Through The Cracks: The Case Of Syrian Women In Egypt After 2011, Ola Dayeh Jan 2024

Blooming Through The Cracks: The Case Of Syrian Women In Egypt After 2011, Ola Dayeh

Theses and Dissertations

This study was conducted in 2023 and aims to understand the impact of displacement on Syrian women’s involvement in the public sphere in Egypt. After the transition of the Syrian revolution into an armed conflict, Syrians witnessed a large wave of displacement, looking for safety away from their homeland. The research defines displacement as the movement of people who are forced to leave their place of residence. The focus is directed on the situation of Syrian women who were displaced to Egypt after 2011, and it proves the claims that there is an increase in women’s engagement in the public …


Development Of An Electromagnetic System For Wireless Magnetic Manipulation Of Soft Capsule Endoscope For Drug Delivery Applications, Nada Ashraf Hussein Mahmoud Jan 2024

Development Of An Electromagnetic System For Wireless Magnetic Manipulation Of Soft Capsule Endoscope For Drug Delivery Applications, Nada Ashraf Hussein Mahmoud

Theses and Dissertations

Wireless capsule endoscopy (WCE) is a remarkable diagnostic device that examines the gastrointestinal (GI) tract. The WCE is a small capsule integrated with a camera that is used to visualize the inner mucosa of the GI tract. WCE has been proven to be the most effective method to diagnose GI diseases and GI cancers. The procedure reduces the discomfort and risk compared to conventional endoscopy methods. However, current WCEs lack the ability to take a biopsy or deliver a drug to a specific location. Those therapeutic functions can be introduced by wirelessly controlled WCEs. This thesis introduces an electromagnetic system …


Native Speakerism In Egypt: The Perceptions Of Non-Native English-Speaking Teachers (Nnests) And Their Employability, Dina Bebars Jan 2024

Native Speakerism In Egypt: The Perceptions Of Non-Native English-Speaking Teachers (Nnests) And Their Employability, Dina Bebars

Theses and Dissertations

Discriminatory hiring practices toward non-native English-speaking teachers (NNESTs) have been researched, debated, and criticized globally. Yet, such recruitment practices are still prevalent in the TESOL field due to perceptions of the linguistic prowess of the native English-speaking teacher (NEST). Given the existence of such practices, this study aims to identify the criteria that employers look for when hiring English language teachers in Cairo, to examine how nativeness is ranked within these criteria, and to investigate if there is a connection between the perceptions of administrators, parents, and teachers regarding NNESTs and hiring practices. A mixed-methods research design was employed to …


An Examination Of The Determinants Of Ease Of Doing Business: Perspectives From World Economies, Omar Eldarawy Jan 2024

An Examination Of The Determinants Of Ease Of Doing Business: Perspectives From World Economies, Omar Eldarawy

Theses and Dissertations

This thesis’ purpose is to explore the correlation between Ease of Doing Business sub-scores and the overall Ease of Doing Business score. The study includes a detailed quantitative study into the previously mentioned relationship. The Ease of Doing Business sub-scores comprise of scores representing starting a business, dealing with construction permits, getting electricity, registering property, getting credit, protecting minority investors, paying taxes, trading across borders, enforcing contracts, and resolving insolvency. This is conducted via a series of diagnostic tests to identify an appropriate regression model. These tests include the Hausman Test, RESET Test, and Breusch-Pagan Test. Based on the tests, …


Thin-Film Nanocomposite Membranes With Alumina Nanoparticles For Textile Wastewater Treatment Applications, Amr Mohamed Tayel Jan 2024

Thin-Film Nanocomposite Membranes With Alumina Nanoparticles For Textile Wastewater Treatment Applications, Amr Mohamed Tayel

Theses and Dissertations

Thin-film nanocomposite (TFN) membranes are gaining great interest in industrial wastewater treatment due to their superior performance, especially for higher water flux and pollutants’ rejection, as well as improved chemical, thermal and mechanical stabilities, compared to other types of membranes. The performance of TFN membranes can be enhanced using different types of nanofillers, among which ceramic nanomaterials, such as Al2O3, offer a promising potential for applications involving treatment of industrial wastewater such as textile effluents, and this is due to their stability, hydrophilicity, and relative low cost. The study of the TFN membrane properties and structure allows the optimization and …


An Examination Of The Determinants Of Ease Of Doing Business: Perspectives From World Economies, Omar Eldarawy Jan 2024

An Examination Of The Determinants Of Ease Of Doing Business: Perspectives From World Economies, Omar Eldarawy

Theses and Dissertations

This thesis’ purpose is to explore the correlation between Ease of Doing Business sub-scores and the overall Ease of Doing Business score. The study includes a detailed quantitative study into the previously mentioned relationship. The Ease of Doing Business sub-scores comprise of scores representing starting a business, dealing with construction permits, getting electricity, registering property, getting credit, protecting minority investors, paying taxes, trading across borders, enforcing contracts, and resolving insolvency. This is conducted via a series of diagnostic tests to identify an appropriate regression model. These tests include the Hausman Test, RESET Test, and Breusch-Pagan Test. Based on the tests, …


Exploring Syrian Practices As New Possibilities: A Comparative Study Of Urban Catalysts At Al-Hossary And El-Rehab Through Deleuze’S Analysis Of Ruptures, Samar Green Jan 2024

Exploring Syrian Practices As New Possibilities: A Comparative Study Of Urban Catalysts At Al-Hossary And El-Rehab Through Deleuze’S Analysis Of Ruptures, Samar Green

Theses and Dissertations

Times of crisis can be theorized from a Deleuzian perspective as a ‘rupture’ to the normative modes of living, where, in the case of politically driven migration, both the displaced population and the host society are impacted by imperative change. Recognizing the transformative nature of these ruptures is crucial as they offer the potential to transition from one paradigm to another.

This research aims to investigate how the displaced Syrian population inhabit the new settlements of Al Hossary Area in 6 October and El Rehab City gated community Souk in New Cairo differently due to the limitations and opportunities their …


The Effect Of Pandemic Shocks On The Performance Of Middle Eastern And African Firms: How Did The Debt Strategy Shape This Effect?, Farah Medhat Elnady Jan 2024

The Effect Of Pandemic Shocks On The Performance Of Middle Eastern And African Firms: How Did The Debt Strategy Shape This Effect?, Farah Medhat Elnady

Theses and Dissertations

This paper studies the impact of the Covid-19 pandemic on financial services firms operating in Middle Eastern and African (“MEA”) countries. The methodology utilized firm-level data from MEA countries, employing the panel regression techniques using fixed and random effects models to control for the potential omitted variable bias. The results of the study underlay that (1) With every 1% increase in new Covid-19 cases market capitalization for firms operating within financial services in MEA countries decreases by 0.11%. (2) Highly indebted financial services firms are more responsive to the Covid-19 pandemic, while low debt firms happen to be more resilient …


Bmfou Pilot Project Rfc - Request For Change, Wsp Environment & Infrastructure, Inc., Nikia Greene, Daryl Reed Jan 2024

Bmfou Pilot Project Rfc - Request For Change, Wsp Environment & Infrastructure, Inc., Nikia Greene, Daryl Reed

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.


Cardiac Active Tension Modeling Via Genetic Algorithm-Optimized Fractional Order Systems, Afnan Khaled Elhamshari Jan 2024

Cardiac Active Tension Modeling Via Genetic Algorithm-Optimized Fractional Order Systems, Afnan Khaled Elhamshari

Theses and Dissertations

Developing a computational model to model cardiac activity has been increasingly important in recent decades. Accurate cell-level active tension modeling for cardiomyocytes is critical to understanding cardiac functionality on a patient-specific basis and developing an effective in-silico cardiac model. However, cell-level models in the literature fail to account for viscoelasticity and inter-patient variations in active tension. This research proposes a genetic algorithm-optimized, fractional order system to model cell-level active tension by extending Land’s state-of-the-art model of cardiac contraction. The model features the (left) Caputo derivative of six state variables that identify the mechanistic origins of viscoelasticity in a myocardial cell …


Implementing Universal Health Insurance: Case Study Of Stakeholders' Perspectives In Port Said, Egypt, Rana Hetta Jan 2024

Implementing Universal Health Insurance: Case Study Of Stakeholders' Perspectives In Port Said, Egypt, Rana Hetta

Theses and Dissertations

This research delves into the multifaceted dimensions of healthcare access through the lens of stakeholders in Port Said, Egypt, following the implementation of Universal Health Insurance (UHI) policies. The central research question explores the impact of UHI policies on healthcare access in Port Said. A set of investigative questions guides this exploration, focusing on beneficiary experiences, healthcare staff perspectives, and the alignment of UHI system implementation with beneficiaries’ healthcare needs. This study seeks to comprehend the institutional and policy context of UHI in Egypt, providing insights from policymakers, healthcare workers, and beneficiaries. Port Said serves as a case study, given …


Nanostructured Cu-Zn Electrode Materials For Green Hydrogen Production, Rahma Leil Jan 2024

Nanostructured Cu-Zn Electrode Materials For Green Hydrogen Production, Rahma Leil

Theses and Dissertations

The continuity of human civilization heavily depends on securing sources of energy. After the 1970s energy crisis, scientists and engineers are meticulously looking for fuels that are alternatives to fossil fuels. Hydrogen can store solar energy to be further used as a fuel. One of the renewable ways to produce hydrogen is Photoelectrochemical (PEC) water splitting. PEC water splitting is a promising way to produce green hydrogen. However, one of the bottlenecks in realizing scalable green hydrogen production systems is the inability to identify and fabricate earthabundant, stable, and durable photocathodes. The main challenges with the reported photocathodes so far …


Preliminary Investigation Of Urban Quality Of Life: Towards Effective Measurements Of Wellbeing In New Urban Communities In Cairo., Aly Elnady Jan 2024

Preliminary Investigation Of Urban Quality Of Life: Towards Effective Measurements Of Wellbeing In New Urban Communities In Cairo., Aly Elnady

Theses and Dissertations

This study focuses on investigating Urban Quality of Life (UQoL) in New Cairo as a case study for New Urban Communities (NUCs) in the Greater Cairo Region. The objective of this thesis is to get an accurate description of urban life in NUCs as a distinct mode of urbanization. The study investigates residents’ Subjective Well Being (SWB) and life satisfaction within a wide range of urban life domains, grouped in a conceptual framework of seven sections: Housing & Neighbourhood Quality, Transport & Mobility, Health & Wellness, Education & Employment, Culture & Recreation, Social & Community Support, and Governance & Neighbourhood …


Clean Drinking Water Access In Egypt’S Marginalized Areas: A Case Study Of Life From Water Foundation, Walaa Nasser Mansy Jan 2024

Clean Drinking Water Access In Egypt’S Marginalized Areas: A Case Study Of Life From Water Foundation, Walaa Nasser Mansy

Theses and Dissertations

Egypt currently suffers from marked water scarcity due to its vulnerability to climate change, uneven water distribution, degradation of water quality, and misuse of water resources in rural and peri-urban areas, leading to health risks and poor hygiene. It is worth noting that Egypt is at a turning point in facing the impacts of climate change action and continuing its national development of water resources to ensure access to safe drinking water and sanitation services to cover the rapid demands of all beneficiaries. However, there is a vulnerability in many marginalized rural and peri-urban areas as they still face a …


Solutions Journalism And Climate Change Journalistic Narratives: Comparative Insights From Egypt And The United Arab Emirates, Nouran Nour Abdelghaffar Jan 2024

Solutions Journalism And Climate Change Journalistic Narratives: Comparative Insights From Egypt And The United Arab Emirates, Nouran Nour Abdelghaffar

Theses and Dissertations

Due to the heavy nature of the climate crisis, climate change news tends to be massively negative. Too much negative information can cause severe psychological impacts and spur news avoidance. Along these lines, solutions-focused climate change reporting presents a juncture for introspection. Solutions journalism is rigorous and compelling reporting about responses to social problems. Focus on the positive while not ignoring the negative; a solution approach could help expand climate coverage by changing the traditional depressing narrative and sharing stories of effective responses. Despite the academia’s growing interest in solutions journalism, there is not an abundance of literature available in …


Towards A Sustainable Model For Finishing Materials In Mixed-Use Gated Community Buildings, Dina Mohamed Shawky Ismail Jan 2024

Towards A Sustainable Model For Finishing Materials In Mixed-Use Gated Community Buildings, Dina Mohamed Shawky Ismail

Theses and Dissertations

ABSTRACT

The concept of sustainability has recently become widespread, and most industries attempt to fulfill all requirements to qualify as sustainable. The construction industry is a prime polluting activity that contributes significantly to carbon dioxide (CO2) emissions. Moreover, use of specific finishing materials such as paint and coatings adds to the emission of volatile organic compounds (VOC) which are extremely harmful to the human health. Hence, proper choice of building and finishing materials can potentially reduce such emissions and takes the building a step closer to qualify a building as a sustainable one. While the construction industry in …


Exploring The Relationships Between Health Literacy And Hba1c In A Rural Border Region, Stephen Jaime Jan 2024

Exploring The Relationships Between Health Literacy And Hba1c In A Rural Border Region, Stephen Jaime

Dissertations

Aims/Objectives: The purpose of this study was to describe the relationships between select sociodemographic and clinical characteristics, individual health literacy levels, and hemoglobin A1c (HbA1c) levels among Hispanic patients with diabetes living in a rural border region.

Background: The frequency of complications from diabetes can increase as HbA1c levels rise, causing the person with diabetes to be at greater risk for blindness, amputation, or renal failure. Unfortunately, people of Hispanic background are at higher risk of developing diabetes compared to non-Hispanic Whites. Many people living in rural towns that border Mexico are of Hispanic background, increasing their risk of developing …


Potential Causal Association Between Gut Microbiome And Posttraumatic Stress Disorder, Qiang He, Wenjing Wang, Dingkang Xu, Yang Xiong, Chuanyuan Tao, Chao You, Lu Ma, Junpeng Ma, Caroline M. Nievergelt, Adam X. Maihofer, Torsten Klengel, Elizabeth G. Atkinson, Chia Yen Chen, Karmel W. Choi, Jonathan R.I. Coleman, Shareefa Dalvie, Laramie E. Duncan, Mark W. Logue, Allison C. Provost, Andrew Ratanatharathorn, Murray B. Stein, Katy Torres, Allison E. Aiello, Lynn M. Almli, Ananda B. Amstadter, Søren B. Andersen, Ole A. Andreassen, Paul A. Arbisi, Ariane Rung, Et Al Jan 2024

Potential Causal Association Between Gut Microbiome And Posttraumatic Stress Disorder, Qiang He, Wenjing Wang, Dingkang Xu, Yang Xiong, Chuanyuan Tao, Chao You, Lu Ma, Junpeng Ma, Caroline M. Nievergelt, Adam X. Maihofer, Torsten Klengel, Elizabeth G. Atkinson, Chia Yen Chen, Karmel W. Choi, Jonathan R.I. Coleman, Shareefa Dalvie, Laramie E. Duncan, Mark W. Logue, Allison C. Provost, Andrew Ratanatharathorn, Murray B. Stein, Katy Torres, Allison E. Aiello, Lynn M. Almli, Ananda B. Amstadter, Søren B. Andersen, Ole A. Andreassen, Paul A. Arbisi, Ariane Rung, Et Al

School of Public Health Faculty Publications

Background: The causal effects of gut microbiome and the development of posttraumatic stress disorder (PTSD) are still unknown. This study aimed to clarify their potential causal association using mendelian randomization (MR). Methods: The summary-level statistics for gut microbiome were retrieved from a genome-wide association study (GWAS) of the MiBioGen consortium. As to PTSD, the Freeze 2 datasets were originated from the Psychiatric Genomics Consortium Posttraumatic Stress Disorder Working Group (PGC-PTSD), and the replicated datasets were obtained from FinnGen consortium. Single nucleotide polymorphisms meeting MR assumptions were selected as instrumental variables. The inverse variance weighting (IVW) method was employed as the …


Lindenwood Digest, January 31, 2024, Lindenwood University Jan 2024

Lindenwood Digest, January 31, 2024, Lindenwood University

Lindenwood Digest

The Lindenwood Digest has been a digital employee newsletter since 2009.


Verbal Abuse, Violence Prevention Climate, And Psychological Safety Among Pediatric Nurses, Donna Bigani Jan 2024

Verbal Abuse, Violence Prevention Climate, And Psychological Safety Among Pediatric Nurses, Donna Bigani

Dissertations

Purpose: The purpose of this study was to describe the relationships among demographic characteristics, verbal abuse, violence prevention climate, and team psychological safety.

Specific Aims: Specific aims were to describe: (1) demographic characteristics, verbal abuse, violence prevention climate, and the perception of team psychological safety by pediatric nurses; (2) relationships among select demographic characteristics, verbal abuse, violence prevention climate, and team psychological safety; and (3) the variance in team psychological safety accounted for by select demographic characteristics, verbal abuse, and violence prevention climate.

Background: Psychological safety is a key element for nursing practice and healthcare teams. Patient and employee safety …


Bordered Youth: Analysing Citizenship And Identities In Post-Brexit Northern Ireland, Mark Holton, Suzanne Beech, Sara Mcdowell, Amy Reid Jan 2024

Bordered Youth: Analysing Citizenship And Identities In Post-Brexit Northern Ireland, Mark Holton, Suzanne Beech, Sara Mcdowell, Amy Reid

School of Geography, Earth and Environmental Sciences

“Young people living in the North of Ireland are put into boxes which perhaps do not adequately represent their views and opinions – the Bordered Youth Project seeks to change that”.This project analyses how young people negotiate the complex and overlapping identities and citizenships produced by living in border regions. We are working with young people aged 18 to 24 living in Northern Ireland, using creative participatory methods to assess how their interpretations, imaginations and encounters with bordered spaces shape, or are shaped by, their everyday movements and cultural interactions. The question of citizenship in a Northern Irish context is …


Harnessing Physical Activity Monitoring And Digital Biomarkers Of Frailty From Pendant Based Wearables To Predict Chemotherapy Resilience In Veterans With Cancer, Gozde Cay, Yvonne H Sada, Mohammad Dehghan Rouzi, Md Moin Uddin Atique, Naima Rodriguez, Mehrnaz Azarian, M G Finco, Sarvari Yellapragada, Bijan Najafi Jan 2024

Harnessing Physical Activity Monitoring And Digital Biomarkers Of Frailty From Pendant Based Wearables To Predict Chemotherapy Resilience In Veterans With Cancer, Gozde Cay, Yvonne H Sada, Mohammad Dehghan Rouzi, Md Moin Uddin Atique, Naima Rodriguez, Mehrnaz Azarian, M G Finco, Sarvari Yellapragada, Bijan Najafi

Center on Aging Staff Publications

This study evaluated the use of pendant-based wearables for monitoring digital biomarkers of frailty in predicting chemotherapy resilience among 27 veteran cancer patients (average age: 64.6 ± 13.4 years), undergoing bi-weekly chemotherapy. Immediately following their first day of chemotherapy cycle, participants wore a water-resistant pendant sensor for 14 days. This device tracked frailty markers like cadence (slowness), daily steps (inactivity), postural transitions (weakness), and metrics such as longest walk duration and energy expenditure (exhaustion). Participants were divided into resilient and non-resilient groups based on adverse events within 6 months post-chemotherapy, including dose reduction, treatment discontinuation, unplanned hospitalization, or death. A …


Comparison Of Perioperative And Postoperative Outcomes Among 3 Left Atrial Incisions: Conventional Direct, Transseptal, And Superior Septal Left Atriotomy, Estelle Démoulin, Dionysios Adamopoulos, Tornike Sologashvili, Mathieu Van Steenberghe, Jalal Jolou, Haran Burri, Christoph Huber, Mustafa Cikirikcioglu Jan 2024

Comparison Of Perioperative And Postoperative Outcomes Among 3 Left Atrial Incisions: Conventional Direct, Transseptal, And Superior Septal Left Atriotomy, Estelle Démoulin, Dionysios Adamopoulos, Tornike Sologashvili, Mathieu Van Steenberghe, Jalal Jolou, Haran Burri, Christoph Huber, Mustafa Cikirikcioglu

The Texas Heart Institute Journal

BACKGROUND: Achieving optimal exposure of the mitral valve during surgical intervention poses a significant challenge. This study aimed to compare perioperative and postoperative outcomes associated with 3 left atriotomy techniques in mitral valve surgery-the conventional direct, transseptal, and superior septal approaches-and assess differences during the surgical procedure and the postoperative period.

METHODS: Inclusion criteria were patients undergoing mitral valve surgery from January 2010 to December 2020, categorized into 3 cohorts: group 1 (conventional direct; n = 115), group 2 (transseptal; n = 33), and group 3 (superior septal; n = 59). To bolster sample size, the study included patients undergoing …