Digital Commons Network^™

Navigating Title Ix Changes Through The Lived Work Experiences Of Title Ix Investigators, Robert Anthony Braswell

Theses and Dissertations

The purpose of this phenomenological study was to explore the lived work experiences of Title IX Investigators as they navigate their responsibilities amongst the continuous changes to Title IX policies and procedures. The lived work experiences of 12 Title IX investigators were collected through in-depth one-on-one interviews to provide knowledge and contribute to the limited preexisting literature regarding their role. Recommendations were provided for Title IX coordinators and advisory teams to foster a satisfactory work environment for Title IX investigators.

Sustainability Of Biogas Production From Anaerobic Digestion Of Food Waste And Animal Manure, Sharath Kumar Ankathi, Utkarsh S. Chaudhari, Robert Handler, David R. Shonnard

Michigan Tech Publications

Anaerobic digestion (AD) involves a set of microbiological reactions and physio-chemical processes to generate biogas, a mixture of predominantly CH4 and CO2. It is commercialized globally; however, AD has limited commercial applications in the U.S. compared to other regions of the world. The main objective of this article is to review different studies on socio-economic and environmental aspects and policies of biogas/biomethane production and to focus on resource availability. The key outcome from this review shows that the anaerobic digestion of food waste and animal manure has great potential to achieve economic and environmental benefits compared to other waste management …

Environmental Justice Is A Civil Rights Issue, Secretary Deb Haaland

New Mexico Law Review

No abstract provided.

A Primary Purpose Problem: State V. Tsosie, Lana Elledge

New Mexico Law Review

In Crawford v. Washington, the United States Supreme Court held that if statements “were made under circumstances which would lead an objective witness reasonably to believe that the statements would be available for use at a later trial,” then a defendant has the right to confront and cross examine the witness. However, the Court’s subsequent retreat from this ruling and introduction of the primary purpose test in a later decision, created a flawed federal analysis, as seen in State v. Tsosie. In Tsosie, the New Mexico Supreme Court applied the primary purpose test to determine whether statements of the declarant, …

Bioengineered Skin For Diabetic Foot Ulcers: A Scoping Review, Nathaniel R. Primous, Peter Elvin, Kathleen V. Carter, Hagner L. Andrade, Javier La Fontaine, Naohiro Shibuya, Cláudia Cristina Biguetti

School of Podiatric Medicine Publications

Diabetic foot ulcers (DFUs) pose a significant threat to individuals with diabetes mellitus (DM), such as lower limb amputation and severe morbidity. Bioengineered skin substitutes (BSS) are alternatives to traditional interventions for treating DFUs, but their efficacy compared to standard wound care (SWC) or other treatment types, such as allografts, remains unknown. A scoping review of human studies was conducted to identify current approaches in the treatment of DFUs using BSS as compared with other treatment options. Systematic searches in PubMed, Cochrane Library, and Web of Science were conducted to identify comparative studies that enrolled 10 or more patients and …

3.0-T Mr-Guided Transgluteal In-Bore-Targeted Prostate Biopsy Under Local Anesthesia In Patients Without Rectal Access: A Single-Institute Experience And Review Of Literature, Kaustav Bera, Nikhil Ramaiya, Dean Nakamoto, Sree Harsha Tirumani

Faculty Scholarship

Purpose: To describe the technique and evaluate the performance of MRI-guided transgluteal in-bore-targeted biopsy of the prostate gland under local anesthesia in patients without rectal access. Methods: Ten men (mean age, 69 (range 57–86) years) without rectal access underwent 13 MRI-guided transgluteal in-bore-targeted biopsy of the prostate gland under local anesthesia. All patients underwent mp-MRI at our institute prior to biopsy. Three patients had prior US-guided transperineal biopsy which was unsuccessful in one, negative in one, and yielded GG1 (GS6) PCa in one. Procedure time, complications, histopathology result, and subsequent management were recorded. Results: Median interval between rectal surgery and …

The Myth Of Anonymity: De-Identified Data As Legal Fiction, Elodie Currier Stoffel

New Mexico Law Review

The unregulated collection, processing, and sale of consumer data has led to a plethora of social and legal issues. As regulators attempt to catch up with the “move fast and break things” ethos of tech innovation, “de-identified” or “anonymized” data has remained broadly unprotected. However, computer science literature shows us that “de-identified” data is a legal fiction. This Article examines the source of the de-identification fiction, analyzes the definitions in new state laws which attempt to close the loophole, tracks potential harms, and proposes a legislative solution which aims to ameliorate some of the legal fictions’ negative impacts. Part I …

Rule 11 Sanctions For Bad Discovery Advocacies, Jeffrey A. Parness, Alexandria N. Short

New Mexico Law Review

For over eighty years, Rule 11 of the Federal Rules of Civil Procedure has authorized sanctions to combat frivolous legal arguments and factual allegations in some paper presentations. Since 1993, however, the rule has not applied to discovery. This article demonstrates how Rule 11 should be used to deter advocacy based on discovery that has “gone bad” since its initial disclosure. Disciplinary actions, malpractice claims, the discovery rules, and even the inherent sanctioning authority of the court are insufficient to deter lawyers from relying on now-bad discovery papers. Rule 11 would hold lawyers to a duty of reasonable inquiry before …

Front Matter, New Mexico Law Review

New Mexico Law Review

No abstract provided.

Growing Through Adversity: The Relation Of Early Childhood Educator Post-Traumatic Growth To Young Children’S Executive Function, Caron A. C. Clark, Holly Hatton-Bowers, Kimia Akhavein, Sarah Rasby, Gilbert R. Parra

Department of Educational Psychology: Faculty Publications

Introduction: Early childhood educators (ECEs) play a critical role in supporting the development of young children’s executive functions (EF). EF, in turn, underpins lifelong resilience and well-being. Unfortunately, many ECEs report adverse childhood experiences (ACEs) that may compound high stress levels associated with an emotionally and physically demanding profession. ACEs have well-established negative implications for adult well-being and may dampen ECEs’ capacities to engage in emotionally responsive interactions with children. However, many individuals who experience ACEs also report post-traumatic growth experiences that foster empathy, self-determination, and resilience. Such post-traumatic growth may equip teachers with skills to engage in responsive …

The Bg News February 21, 2024, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. February 21, 2024. Volume 103-Issue 18.

Use Of Crispr Interference For Efficient And Rapid Gene Inactivation In Fusobacterium Nucleatum, Peng Zhou, Bibek G C, Flynn Stolte, Chenggang Wu

Faculty, Staff and Student Publications

Gene inactivation by creating in-frame deletion mutations in Fusobacterium nucleatum is time consuming, and most fusobacterial strains are genetically intractable. Addressing these problems, we introduced a riboswitch-based inducible CRISPR interference (CRISPRi) system. This system employs the nuclease-inactive Streptococcus pyogenes Cas9 protein (dCas9), specifically guided to the gene of interest by a constantly expressed single-guide RNA (sgRNA). Mechanistically, this dCas9-sgRNA complex serves as an insurmountable roadblock for RNA polymerase, thus repressing the target gene transcription. Leveraging this system, we first examined two non-essential genes, ftsX and radD, which are pivotal for fusobacterial cytokinesis and coaggregation. Upon adding the inducer, theophylline, …

Revascularization Strategies For Acute And Chronic Mesenteric Ischemia: A Narrative Review, Jacob J Gries, Takashi Sakamoto, Bing Chen, Hafeez Ul Hassan Virk, Mahboob Alam, Chayakrit Krittanawong

Faculty, Staff and Students Publications

Mesenteric ischemia is a challenging condition characterized by insufficient blood perfusion to the mesentery and, consequently, intestinal tissues that continues to perplex clinicians. Despite its low prevalence, the condition’s variable clinical presentation and elusive radiographic diagnosis can delay life-saving interventions in the acute setting and deteriorate the quality of life of patients when left undiagnosed or misdiagnosed. Purpose: Review and summarize recent diagnostic updates and emergent intervention strategies for acute and chronic mesenteric ischemia. Methods: A narrative review of all relevant studies from January 2022 through September 2023. Results: A total of 11 studies from MEDLINE, supplemented with 44 studies …

Predicting Lemna Growth Based On Climate Change And Eutrophication In Temperate Freshwater Drainage Ditches, Jared Feller, Mark Taylor, Paul Henry Lunt

School of Geography, Earth and Environmental Sciences

The Somerset Levels and Moors, UK is an area of high conservation value, including nationally and internationally protected wetland sites. Duckweed (Lemna) mats in the Somerset Levels and Moors are increasingly common and are an indication of hyper-eutrophication. Duckweed mats can contribute to increased management burdens and decreases in biodiversity. Research suggests duckweed will thrive in temperate regions as the climate warms. This study investigated the impact of climate warming and eutrophication on duckweed growth in the Somerset Levels and Moors using a previously published model to simulate duckweed growth from the years of 2020–2080. Simulated local climate change projections …

Bioinformatics Characterization Of Variants Of Uncertain Significance In Pediatric Sensorineural Hearing Loss, Sloane Clay, Adele Evans, Regina Zambrano, David Otohinoyi, Chindo Hicks, Fern Tsien

School of Medicine Faculty Publications

Introduction: Rapid advancements in Next Generation Sequencing (NGS) and bioinformatics tools have allowed physicians to obtain genetic testing results in a more rapid, cost-effective, and comprehensive manner than ever before. Around 50% of pediatric sensorineural hearing loss (SNHL) cases are due to a genetic etiology, thus physicians regularly utilize targeted sequencing panels that identify variants in genes related to SNHL. These panels allow for early detection of pathogenic variants which allows physicians to provide anticipatory guidance to families. Molecular testing does not always reveal a clear etiology due to the presence of multigenic variants with varying classifications, including the presence …

'Science By Consensus' Impedes Scientific Creativity And Progress: A Simple Alternative To Funding Biomedical Research, Nejat Düzgüneş

Pacific Faculty Work

The very low success rates of grant applications to the National Institutes of Health (NIH) and the National Science Foundation (NSF) are highly detrimental to the progress of science and the careers of scientists. The peer review process that evaluates proposals has been claimed arbitrarily to be the best there is. This consensus system, however, has never been evaluated scientifically against an alternative. Here we delineate the 15 major problems with the peer review process. We challenge the Science Advisor to the President, and the leadership of NIH, NSF, the U.S. National Academy of Sciences and other funding agencies throughout …

Antibody Profiling And Predictive Modeling Discriminate Between Kaposi Sarcoma And Asymptomatic Kshv Infection, Sydney J. Bennett, Dicle Yalcin, Sara R. Privatt, Owen Ngalamika, Salum J. Lidenge, John T. West, Charles Wood

School of Biological Sciences: Faculty Publications

Protein-level immunodominance patterns against Kaposi sarcoma-associated herpesvirus (KSHV), the aetiologic agent of Kaposi sarcoma (KS), have been revealed from serological probing of whole protein arrays, however, the epitopes that underlie these patterns have not been defined. We recently demonstrated the utility of phage display in high-resolution linear epitope mapping of the KSHV latency-associated nuclear antigen (LANA/ORF73). Here, a VirScan phage immunoprecipitation and sequencing approach, employing a library of 1,988 KSHV proteome-derived peptides, was used to quantify the breadth and magnitude of responses of 59 sub-Saharan African KS patients and 22 KSHV-infected asymptomatic individuals (ASY), and ultimately to support an application …

The Impact Of Iron Supplementation On The Preterm Neonatal Gut Microbiome: A Pilot Study, Matthew Van Ormer, Maranda Thompson, Melissa K. Thoene, Jean-Jack Riethoven, Sathish Kumar Natarajan, Ann Anderson-Berry

Department of Nutrition and Health Sciences: Faculty Publications

Objective The gastrointestinal microbiome in preterm infants exhibits significant influence on optimal outcomes–with dysbiosis shown to substantially increase the risk of the life-threatening necrotizing enterocolitis. Iron is a vital nutrient especially during the perinatal window of rapid hemoglobin production, tissue growth, and foundational neurodevelopment. However, excess colonic iron exhibits potent oxidation capacity and alters the gut microbiome–potentially facilitating the proliferation of pathological bacterial strains. Breastfed preterm infants routinely receive iron supplementation starting 14 days after delivery and are highly vulnerable to morbidities associated with gastrointestinal dysbiosis. Therefore, we set out to determine if routine iron supplementation alters the preterm gut …

Connecting In A Remote World: Psychotherapy & Counselling Students’ Experiences Of Remote Teaching And Learning, Geraldine Sheedy

Applied Social Studies

In 2017 Scholl et al. highlighted a growing trend towards online courses in Psychotherapy & Counselling training. With the emergence of the Coronavirus (COVID-19) pandemic, this growth has accelerated, with more training now taking place in an online setting. This study explored students’ experiences of remote learning on a Psychotherapy & Counselling training, with a particular focus on engagement and interaction in an online setting. A Thematic Analysis was carried out on the data and the central organising theme of Connection emerged. Three sub-themes were identified including, ‘Connection to Self’, ‘Connection to Others’ and ‘Connection to Lecturers’. Findings indicate that …

Immunogenicity Phase Ii Study Evaluating Booster Capacity Of Nonadjuvanted Aks-452 Sars-Cov-2 Rbd Fc Vaccine, David G Alleva, Eline A Feitsma, Yester F Janssen, Hendrikus H Boersma, Thomas M Lancaster, Thillainaygam Sathiyaseelan, Sylaja Murikipudi, Andrea R Delpero, Melanie M Scully, Ramya Ragupathy, Sravya Kotha, Jeffrey R Haworth, Nishit J Shah, Vidhya Rao, Shashikant Nagre, Shannon E Ronca, Freedom M Green, Stephen A Shaw, Ari Aminetzah, Schelto Kruijff, Maarten Brom, Gooitzen M Van Dam, Todd C Zion

Faculty, Staff and Students Publications

AKS-452, a subunit vaccine comprising an Fc fusion of the ancestral wild-type (WT) SARS-CoV-2 virus spike protein receptor binding domain (SP/RBD), was evaluated without adjuvant in a single cohort, non-randomized, open-labelled phase II study (NCT05124483) at a single site in The Netherlands for safety and immunogenicity. A single 90 µg subcutaneous booster dose of AKS-452 was administered to 71 adults previously primed with a registered mRNA- or adenovirus-based vaccine and evaluated for 273 days. All AEs were mild and no SAEs were attributable to AKS-452. While all subjects showed pre-existing SP/RBD binding and ACE2-inhibitory IgG titers, 60-68% responded to AKS-452 …

Antibody Profiling And Predictive Modeling Discriminate Between Kaposi Sarcoma And Asymptomatic Kshv Infection, Sydney J. Bennett, Dicle Yalcin, Sara R. Privatt, Owen Ngalamika, Salum J. Lidenge, John T. West, Charles Wood

School of Medicine Faculty Publications

Protein-level immunodominance patterns against Kaposi sarcoma-associated herpesvirus (KSHV), the aetiologic agent of Kaposi sarcoma (KS), have been revealed from serological probing of whole protein arrays, however, the epitopes that underlie these patterns have not been defined. We recently demonstrated the utility of phage display in high-resolution linear epitope mapping of the KSHV latency-associated nuclear antigen (LANA/ORF73). Here, a VirScan phage immunoprecipitation and sequencing approach, employing a library of 1,988 KSHV proteome-derived peptides, was used to quantify the breadth and magnitude of responses of 59 sub-Saharan African KS patients and 22 KSHV-infected asymptomatic individuals (ASY), and ultimately to support an application …

E-Democracy In Indonesia: Use Of Social Media And Challenges In Encouraging Youth Political Participation, Mustabsyirotul Ummah Mustofa, Rafif Sakti Utama, Mutia Kartika Andalus

Jurnal Wacana Politik

A survey released by CSIS in September 2022 showed an increase in internet access for young voters from 2018 to 2022. The survey release showed a significant increase in access to social media as a source of information for young voters 19.5 per cent. Moreover, the CSIS survey found a condition where the interest of young Indonesians is currently very low in politics. On the other hand, hoaxes and misinformation can threaten young voters if they are not equipped with adequate political literacy and understanding. This desk study research was conducted to get an explanation from existing literature of how …

Ensemble Concerts: Morton High School Wind Ensemble, Wind Symphony, Belle Voix; February 21, 2024, Craig Hatter, Katrina Fitzpatrick, John Gonzalez, Anthony C. Marinello Iii, Tj Mack

School of Music Programs

Center for the Performing Arts
February 21, 2024
Wednesday Evening
7:00 p.m.

Overview Of The Alaskan Layered Pollution And Chemical Analysis (Alpaca) Field Experiment, William R. Simpson, Jingqiu Mao, Gilberto J. Fochesatto, Kathy S. Law, Peter F. Decarlo, Julia Schmale, Kerri A. Pratt, Steve R. Arnold, Jochen Stutz, Jack E. Dibb, Jessie M. Creamean, Rodney J. Weber, Brent J. Williams, Becky Alexander, Lu Hu, Robert J. Yokelson, Manabu Shiraiwa, Stefano Decesari, Cort Anastasio, Barbara D’Anna, Robert C. Gilliam, Athanasios Nenes, Jason M. St. Clair, Barbara Trost, James H. Flynn, Joel Savarino, Laura D. Conner, Nathan Kettle, Krista M. Heeringa, Sarah Albertin, Andrea Baccarini, Brice Barret, Michael A. Battaglia, Slimane Bekki, T. J. Brado, Natalie Brett, David Brus, James R. Campbell, Meeta Cesler-Maloney, Sol Cooperdock, Karolina Cysneiros De Carvalho, Hervé Delbarre, Paul J. Demott, Conor J.S. Dennehy, Elsa Dieudonné, Kayane K. Dingilian, Antonio Donateo, Konstantinos M. Doulgeris, Kasey C. Edwards, Kathleen Fahey, Ting Fang, Fangzhou Guo, Laura M. D. Heinlein, Andrew L. Holen, Deanna Huff, Amna Ijaz, Sarah Johnson, Sukriti Kapur, Damien T. Ketcherside, Ezra Levin, Emily Lill, Allison R. Moon, Tatsuo Onishi, Gianluca Pappaccogli, Russell Perkins, Roman Pohorsky, Jean-Christophe Raut, Francois Ravetta, Tjarda Roberts, Ellis S. Robinson, Federico Scoto, Vanessa Selimovic, Michael O. Sunday, Brice Temime-Roussel, Xinxiu Tian, Judy Wu, Yuhan Yang

Faculty Publications

The Alaskan Layered Pollution And Chemical Analysis (ALPACA) field experiment was a collaborative study designed to improve understanding of pollution sources and chemical processes during winter (cold climate and low-photochemical activity), to investigate indoor pollution, and to study dispersion of pollution as affected by frequent temperature inversions. A number of the research goals were motivated by questions raised by residents of Fairbanks, Alaska, where the study was held. This paper describes the measurement strategies and the conditions encountered during the January and February 2022 field experiment, and reports early examples of how the measurements addressed research goals, particularly those of …

How Physicians’ Perceptions Of Satisfaction And Morale Affect Retention, Ernest George Britton

Walden Dissertations and Doctoral Studies

Physician turnover affects care delivery and contributes to costs, emphasizing the need for retention to minimize unnecessary costs of hiring, training, and lost productivity among healthcare organizations. Healthcare leaders tend to be concerned about the negative affects that physician turnover has on patient care, profitability, and organizational viability. The U.S. healthcare system may benefit from reduced expenditures associated with retention. Grounded in Ellenbecker’s job retention model, the purpose of this qualitative multiple-case study was to explore strategies healthcare organizational leaders use to retain employed primary care and internal medicine physicians. The participants comprised six physician leaders from three healthcare organizations …

Evidence-Based Leadership Practices Of Reentry Program Leaders To Reduce Recidivism Among African American Women, Mabrey Raymond Duff

Walden Dissertations and Doctoral Studies

The rate of recidivism among African American women is disproportionately higher than among European American or Latino women in a southeastern state. The problem identified was the high prevalence of recidivism among African American women despite undergoing reentry programs. The purpose of this basic qualitative study was to explore the practices of reentry program leaders in a southeastern state that reduce recidivism among formerly incarcerated African American women. Evidence-based leadership development provided a conceptual framework for assessing the results of practices in the reentry program. Current reentry program leaders in a southeastern state were asked to describe the leadership practices …

Orbital And Periocular Complications In Patients With Sinonasal Tumours With Orbital Invasion, Jiawei Zhao, Xinyang Jiang, Ehab Hanna, Shirley Y Su, Amy Moreno, Brandon Gunn, Steven Jay Frank, Renata Ferrarotto, Jing Ning, Bita Esmaeli

Faculty, Staff and Student Publications

Aims: The purpose of this study was to determine the frequency and associated risk factors of orbital/periocular complications in patients with sinonasal tumour with orbital invasion managed with eye-sparing treatments.

Methods: A retrospective case series of patients with primary sinonasal tumour with orbital invasion from January 2008 to December 2018. Patient factors were compared between the following groups: (1)patients with orbital/periocular complications versus those who did not and (2) patients who needed secondary oculoplastic surgical procedures versus those who did not.

Results: Out of 80 patients, 48 had eye-sparing surgery, 8 had orbital exenteration and 24 were managed non-surgically. The …

Quantifying Wildfire Drivers And Predictability In Boreal Peatlands Using A Two-Step Error-Correcting Machine Learning Framework In Tefire V1.0, Rongyun Tang, Mingzhou Jin, Daniel M. Ricciuto, Anping Chen, Yulong Zhang

Biological and Agricultural Engineering Faculty Publications and Presentations

Wildfires are becoming an increasing challenge to the sustainability of boreal peatland (BP) ecosystems and can alter the stability of boreal carbon storage. However, predicting the occurrence of rare and extreme BP fires proves to be challenging, and gaining a quantitative understanding of the factors, both natural and anthropogenic, inducing BP fires remains elusive. Here, we quantified the predictability of BP fires and their primary controlling factors from 1997 to 2015 using a two-step correcting machine learning (ML) framework that combines multiple ML classifiers, regression models, and an error-correcting technique. We found that (1) the adopted oversampling algorithm effectively addressed …

Data Encoding For Healthcare Data Democratization And Information Leakage Prevention, Anshul Thakur, Tingting Zhu, Vinayak Abrol, Jacob Armstrong, Yujiang Wang, David A Clifton

Faculty, Staff and Student Publications

The lack of data democratization and information leakage from trained models hinder the development and acceptance of robust deep learning-based healthcare solutions. This paper argues that irreversible data encoding can provide an effective solution to achieve data democratization without violating the privacy constraints imposed on healthcare data and clinical models. An ideal encoding framework transforms the data into a new space where it is imperceptible to a manual or computational inspection. However, encoded data should preserve the semantics of the original data such that deep learning models can be trained effectively. This paper hypothesizes the characteristics of the desired encoding …

Collagen Type Xii Is Undetectable In Keratoconus Bowman’S Layer, Mohammed Rigi, Hyeck-Soo Son, Loren Moon, Mario Matthaei, Divya Srikumaran, Albert S Jun, Charles G Eberhart, Uri S Soiberman

Faculty, Staff and Student Publications

PURPOSE: Corneal biomechanical failure is the hallmark of keratoconus (KC); however, the cause of this failure remains elusive. Collagen type XII (

METHODS: TaqMan quantitative PCR was performed on 31 corneal epithelium samples of progressive KC and myopic control eyes. Tissue microarrays were constructed using full-thickness corneas from 61 KC cases during keratoplasty and 18 non-KC autopsy eyes and stained with an antibody specific to COL12A1. Additionally,

RESULTS: COL12A1 expression was reduced at transcript levels in KC epithelium compared to controls (ratio: 0.58, p<0.03). Immunohistochemical studies demonstrated that COL12A1 protein expression in BL was undetectable, with reduced expression in KC epithelium, basement membrane, and stroma.

CONCLUSIONS: The apparent absence of COL12A1 in KC BL, together with the functional importance that