Digital Commons Network^™

Early-Stage Rectal Mixed Neuroendocrine-Non-Neuroendocrine Neoplasm Treated With Local Excision In A Frail Elderly Patient: A Multidisciplinary Management Dilemma, Christopher M. Ahmad, Rae-Anne Kastle, Talyn Smith, Harsha Kalagana, Kerry Williams-Wuch

Student Publications

Mixed neuroendocrine-non-neuroendocrine neoplasms (MiNENs) of the rectum are rare tumors that typically demonstrate aggressive behavior, largely driven by high-grade neuroendocrine carcinoma components. Evidence guiding management is limited, particularly for early-stage lesions and for patients unable to tolerate standard oncologic surgery. We report the case of an elderly man with extensive comorbidities who was found to have a 1.3 cm rectal MiNEN following transanal endoscopic microsurgery (TEMS) performed for rectal bleeding. Histopathology revealed a moderately differentiated adenocarcinoma component and a well-differentiated grade 1 neuroendocrine tumor (NET) component, with submucosal invasion greater than 2 mm, negative margins, low tumor budding, small-vessel lymphovascular …

Transcriptome Predictors Of Second Breast Events In Ductal Carcinoma In Situ: A Case‒Control Study Including Black And White Women, Aditi Hazra, Emma Berdan, Thomas Walsh, Sarah Humble, Jen Tappenden, Katherine Deschryver, Deborah Veis, Kiran Vij, Shannan Ho Sui, Graham A Colditz

2020-Current year OA Pubs

BACKGROUND: Black women diagnosed with ductal carcinoma in situ (DCIS) experience disproportionately higher risk of second breast cancer events (SBEs), including both ipsilateral and contralateral recurrences, yet remain underrepresented in molecular biomarker studies compared to non-Hispanic White women.

METHODS: We performed RNA sequencing on 200 archival DCIS samples from the Resource of Archival Breast Tissue cohort, including 33% self-reported Black women. We correlated transcriptomic and clinical data to identify predictors of SBEs. Cases (n = 100) who developed SBEs between 1999 and 2019 were matched 1:1 to controls (n = 100) on age, race, and margin status, who remained event-free …

Pest Risk Modelling For Climate-Smart Vegetable Production In East Africa, Marc Marin Agbodjan, Komi Mensah Agboka, John Odindi, Elfatih Abdel-Rahman, Onisimo Mutanga, Frank Chidawanyika, Chrysantus Tanga, Daniel Munyao Mutyambai, Sevgan Subramanian, Bonoukpoè Mawuko Sokame

All Peer-Reviewed Publications

Agricultural productivity in East Africa is increasingly threatened by climate-sensitive insect pests. This study investigates the occurrence of key vegetable pests: Brevicoryne brassicae, Plutella xylostella, Maruca vitrata, and Liriomyza mik. A comparative species distribution modelling evaluated pest risk projections under climate change. Four variable selection strategies were tested: case 1 (correlation and variance inflation factor [VIF] filtering across all predictors), case 2 (correlation and VIF filtering of bioclimatic variables merged with other predictors), case 3 (filtering based on environmental values at species occurrence point to approximate realized niches), and case 4 (dimensionality reduction using principal component analysis). These strategies were …

Contemplative Classrooms For Ecological Wisdom: Reimagining K-12 Education In Pakistan, China, And Beyond, Maha Shoaib, Jing Lin, Yueyue Wang

Journal of Contemplative and Holistic Education

This paper explores the transformative potential of contemplative environmental education in addressing the growing disconnection between humans and the natural world, particularly within K-12 education systems shaped by anthropocentric and capitalist paradigms. Modern schooling often frames nature as an object of study, rather than a sacred, living presence, contributing to ecological alienation amid intensifying environmental crises. We propose a radical shift toward contemplative, holistic education that draws on spiritual, Indigenous, and ecological knowledge systems. Grounded in Daoist philosophy, Islamic teachings on stewardship, Hindu ethics, and Indigenous worldviews, we reimagine education as a relational and sacred engagement with the Earth. We …

Reimagining Masculinities Through Australian Indigenous Pedagogies, Ben Campbell, Anna Rumjahn

Journal of Contemplative and Holistic Education

In the face of intersecting ecological crises and persistent gender inequality, this paper explores how dominant norms of masculinity—marked by control, detachment, conquest, and other ideals rooted in Western, hegemonic paradigms—contribute to environmental degradation. Drawing on ecofeminist theory, Australian Indigenous pedagogies, and contemplative education, we examine how relational, place-based approaches may offer transformative alternatives for boys in schooling contexts. Central to this inquiry is the Learning from Country framework, which positions land as teacher and emphasizes practices of deep listening, reciprocity, and ethical engagement with the more-than-human world.

We argue that this pedagogical approach challenges dominant masculinities by fostering care …

Challenging Stem Learning Spaces: The Paradigm Of Contemplative Traditions As The Bedrock Of Creativity And Healing, Raaghav Pandya, Christopher Emdin

Journal of Contemplative and Holistic Education

As the post-pandemic classroom and pedagogy evolve to remedy oppressive norms, young people’s mental health and alienation has taken front stage (Rahmani & Zitouni, 2022). Traditional STEM learning spaces often teach inquiry as a linear, non-deviated approach to problems about self and nature (Hrisa & Psillos, 2022). Furthermore, because our classrooms often strip students and educators of their inherent creative abilities through constant assessments, improvement scales, and market-driven expectations, classrooms cease to become places of healing (Pandya, 2021). Eastern wisdom traditions and their associated philosophies provide a unique pedagogical lens that emphasizes a deep inquiry into self, empathy, and creativity …

Journeys Of Two Children From West To East: Notes Of A Teacher-Parent, Katherine E. Khan Dr

Journal of Contemplative and Holistic Education

This essay, explores the transformative educational journeys of two children across five countries, viewed through the dual lens of a teacher and parent. Grounded in the principles of Contemplative Education (CE), it draws on over two decades of the author’s experience in global education, weaving personal and professional insights into a narrative that examines how context, culture, and pedagogy intersect in shaping young learners.

The journey begins in the inquiry-rich, nature-based kindergartens of Germany and the nurturing early primary years of the United Kingdom, moves through the International Baccalaureate (IB) Primary and Middle Years Programmes, and Big Picture education in …

Teachers As Wisdom Workers Of Love: A Radical Reconceptualization Of Teacher Education Centering Wholeness, Compassion, And Interbeing In A Fractured World, Yueyue Wang, Jing Lin, Maha Shoaib, Anna Lytkina

Journal of Contemplative and Holistic Education

Amid global crises and rising teacher burnout, current teacher education often prioritizes technical skills and standardized competencies while neglecting the inner life, relational presence, and spiritual vitality essential for sustaining educators. This article reconceptualizes teacher preparation by envisioning teachers as “wisdom workers of love” -- healers, guides, and community nurturers grounded in wholeness, compassion, and interbeing. Drawing from Daoism, Ubuntu, contemplative pedagogy, and Indigenous epistemologies, this study employs collaborative autoethnography as contemplative inquiry, weaving narratives from educators in China, Pakistan, Russia, and the United States. Through mutual witnessing and collective reflection, we identify five interrelated dimensions for cultivating love-based education: …

Reimagining Teacher-Student Relationships In Schools: What Does Mencius Say?, Ruo-Han Wang, Charles Scott

Journal of Contemplative and Holistic Education

In some K-12 educational settings, it is often assumed that teachers are the ones who deliver and guide, while students are the ones who are delivered and guided. As a result, both in common perception and practical operations, teachers typically hold more power than students, acting as both the possessors and executers of authority. While this inherent power imbalance in traditional schools is understandable, it can create fundamental situations that remain unresolved, representing an ontological problem in education . These fundamental issues have persisted in causing trauma in educational settings (Frieze, 2015), and the need for healing for both students …

Beyond Coping In High School: An Emergent Mindfulness Practice Towards Embodied Wisdom, Mel A.V. Voulgaris

Journal of Contemplative and Holistic Education

Mindfulness practice is trending in schools. Within secondary education, it is oftentimes introduced as meditation for present-moment awareness of the self to support academic concerns. However, mindfulness practice in its original conception is a holistic way of cultivating human well-being towards flourishing. It is a practice that aims for awareness to the entirety of human subjective and intersubjective experiencing as it is emerging. In doing so, mindfulness evolves from a coping tool into a rich contemplative practice. This paper will make the case that mindulness as a contemplative practice facilitates the cultivation of embodied wisdom and that such a practice …

The Wisdom-Centered Classroom: Contemplative Pathways To Healing, Interbeing, And Peace In K–12 Education, Hyeyoung Bang, Jing Lin, Heesoon Bai, Deepa Srikantaiah, Charles Scott, Denise L. Mchugh

Journal of Contemplative and Holistic Education

While contemporary educational goals often prioritize economic advancement and labor-market readiness, a profound need exists to re-center schools as environments that nurture the human spirit. Education should move beyond standardization, cultivating schools where students embrace their inherent worth, relate with empathy and kindness, and develop as compassionate citizens regardless of their background. At the Journal of Contemplative and Holistic Education (JCHE), we contend that the cultivation of wisdom must be a primary educational aim. This special issue explores contemplative K–12 pedagogies, inviting experts to examine the realities, possibilities, and systemic challenges of Contemplative Education (CE) from diverse global and Indigenous …

Pemisahan Tanggungjawab Direksi Perseroan Terbatas, Freddy Harris

Jurnal Hukum & Pembangunan

Abstract

Blinded By Relapse: A Rare Case Of Bilateral Vision Loss From Leukemic Meningeal Infiltration, Aun A. Bangash, Tejaswini Swamy, Chloe C. Harris, Victoria Parada

Research Symposium

Background: Acute lymphoblastic leukemia (ALL) accounts for 20% of adult leukemias, with outcomes improving through modern systemic and CNS-directed therapies. Leukemic meningeal relapse, defined as infiltration of the meninges and detected by cerebrospinal fluid cytology, is reported in 4–7% of adult ALL patients and remains a devastating complication despite CNS prophylaxis. CNS involvement typically presents with nonspecific symptoms such as headache, nausea, or cranial neuropathies; isolated, abrupt vision loss is rare. With a median survival of less than six months if untreated, timely recognition is critical. We present a case of intracranial hypertension with bilateral vision loss due to leukemic …

The Noma Model As A Guide To Holistic Healthcare, Elena El Ghossaini

Undergraduate Research and Engagement Symposium

Juggling personal faith without jeopardizing one’s commitment to science is no easy feat, so this analysis examines real world applications of Gould’s Non-Overlapping Magisteria (NOMA) model, specifically in medicine. By incorporating various voices through a literature review and nursing student interviews, this research considers how NOMA can be used to reconcile a healthcare worker’s spirituality with their scientific obligations. Overall, these findings suggest that one’s spiritual beliefs need not interfere with one’s profession. Instead, the NOMA model can be employed to promote meaningful connections with patients, leading to improved cognizance of spiritual needs and more holistic treatment.

Femininity And Dateability: A Look At The Perception Of Asian Faces, Grace Yang

Caravel Undergraduate Research Journal

Over the last decade, Asian Americans are the fastest growing ethnic group in the United States (Lam, 2016), and the visibility of Asian influence on popular culture has increased as well (Jin & Yoon, 2017).  As a fast-growing minority community, the Asian community has been relatively overlooked in studies about attraction and the effects of ideals of masculinity. The aim of the current study was to investigate factors that influence the perception of the Asian and non-Asian faces with respect to attractiveness, dateability and masculinity.  The current literature suggests that both Asian men and women are stereotyped to be relatively …

Parenting Style And Academic Success: How Can You Help Your Child Succeed?, Elizabeth A. Weicker

Caravel Undergraduate Research Journal

The goal of this study was to investigate the relationship between the parenting style a college student experienced during childhood and the student’s most recent college GPA. Using survey data collected from undergraduate students throughout the United States, a between-subjects ANOVA was conducted to comparing different parenting styles and mean GPA for those styles. The parenting styles analyzed were authoritative, authoritarian, and permissive. Results indicated significant differences in GPA between parenting styles, with the authoritative parenting style producing the highest college GPA. In addition, an independent samples t-test was conducted to analyze the relationship between student satisfaction with the parenting …

The Role Of Paraprofessionals In The Mental Health Structure Of India, Amy Abraham, Kimberly D. Becker, Wendy Chu

Caravel Undergraduate Research Journal

The mental health treatment gap in India is part of a growing public health crisis, with over 95% of those in need of services never receiving them. Over 197 million Indians suffer from at least one diagnosable mental health disorder, and this number continues to grow given the treatment gap. The treatment gap is a result of four major factors: lack of government support, stigma, limited treatment facilities, and dearth of professionals able to provide treatment. The current study aimed to analyze several factors of paraprofessional-led mental health interventions including setting, treatments delivered, treatment models, and client outcomes. A narrative …

Searching For A Connection Between Intellectual Humility And Decision-Making Ability, Mansi Verma, Kristin Kirchner

Caravel Undergraduate Research Journal

The present study investigated whether there was a relationship between intellectual humility and decision-making. The participants were 32 undergraduate students recruited from the University of South Carolina. Data was collected through self-reported measures of intellectual humility from the participants and their answers to questions testing for decision-making ability in a single survey. Results indicate that there is a correlation between the scores on the Intellectual Humility Scale and CRT scores. Overall, there does appear to be a relationship between intellectual humility and decision-making.

Moving America: A Study Examining The Relationships Between Early Residential Mobility, Anxiety And Academic Performance, Kelsey Thomas, Wendy Chu, Melanie Palomares

Caravel Undergraduate Research Journal

Early residential mobility has known negative effects on mental health outcomes and academic achievement. These effects have been studied broadly and globally, yet there lacks attention in examining early residential mobility to specific localities, regions, or states. As such, this study sought to investigate these associations, specifically its impact on anxiety and academic performance in adults residing or living in South Carolina. Participants were surveyed online regarding their demographic information, academic performance, and anxiety levels. Results found no significant relationships between early residential mobility, anxiety, and academic performance among adults residing or living in South Carolina. Despite these null findings, …

College Student's Ideal Age For Having Children, Corrie Sanders, Melanie Palomares, Kristin Kirchner

Caravel Undergraduate Research Journal

It has been observed that women are beginning to have children at a later age than traditionally seen in history. This study examines college student’s ideal age for having children, and how it compares to the age of their mother when she had her first child. The data was collected mainly from undergraduate students at the University of South Carolina through a survey completed by 39 participants. Through a one-way between-subjects ANOVA, this study found there was not a significant difference of the ideal age to have children between college students ages 19, 20, 21, 22, and 23. The average …

Examining Biobehavioral Indicators Of Adhd In Children With Fxs, Hannah Pressler, Kayla Smith, Ramsey Coyle, Elizabeth Will, Jane E. Roberts

Caravel Undergraduate Research Journal

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by inattention and hyperactivity/impulsivity behaviors that are inconsistent with developmental age. Children with fragile X syndrome (FXS), a genetic neurodevelopmental disorder, are often diagnosed with comorbid ADHD (53–59% of males with FXS). Despite the prevalence of ADHD in FXS, little is known about the early manifestation of ADHD. The current project aims to explore group differences in play behaviors between children with FXS and typically developing (TD) children as well as the relationship between infant play behavior and heart activity to future ADHD attention outcomes. Participants included male children with FXS and …

Predator Or Prey: The Analysis Of Gender And Race On The Perception Of Black Men As Sexual Assault Victims, Jordyn Livingston, Dr. Florencia Cornet

Caravel Undergraduate Research Journal

Men sexual assault victims have gained more attention in recent years. Despite the growing sociological literature on violence against men, previous research provides little acknowledgment of Black men sexual assault victims. In this manuscript, I analyze emerging literature in the socio-medical sciences to explore how gender and race affects the perceptions of Black men as sexual assault victims. Specifically, I utilize intersectionality as a theoretical framework to synthesize literature on blackness and masculinity in sexual assault victims to conclude that there is an intersectional point that disadvantages Black males, portraying them as sexual predators. In so doing, I provide research …

Optimizing Expression Conditions For The Overexpression Of Iron Regulatory Protein Bol2 From C. Glabrata, Jade Ikahihifo-Bender, Dr. Caryn Outten, Mrs. Evan Talib

Caravel Undergraduate Research Journal

Due to its unique ability to serve as both an electron donor and acceptor, iron is utilized as a co-factor for many biological processes, including electron transfer, oxygen binding, and vitamin synthesis. Iron is also a key factor during fungal infections as the human host and invading pathogens battle over limited iron pools. The primary iron-responsive transcription factor Aft1 in the opportunistic pathogenic yeast Candida glabrata responds to iron deficiency by activating expression of iron acquisition genes. However, the mechanisms for sensing intracellular iron levels and regulating Aft1 activity in response to iron are unknown. The C. glabrata iron regulation …

Effect Of Ampk On Exercise-Induced Adipocyte Metabolism, Alec M. Giakas, Ran Hee Choi, Ho-Jin Koh

Caravel Undergraduate Research Journal

Regular physical activity is a recommended strategy to prevent obesity via increasing fatty acid metabolism. AMP-activated protein kinase (AMPK) has been associated with the activation of lipolysis in adipose tissue. Furthermore, it has been demonstrated that a single bout of exercise increases AMPK activity in adipocytes; however, the mechanism by which AMPK regulates exercise-induced adipocyte metabolism has yet to be determined. To examine the role of AMPK in exercise-induced adipocyte metabolism, we utilized fat-specific AMPK alpha 1 and alpha 2 knockout mice (FKO). Wild type (WT) and FKO mice were divided into sedentary (Sed) and exercise (EX) groups. After 6 …

The Effects Of Eating Disorder Knowledge On Dieting Beliefs, Kaitlyn Finn, Melanie Palomares, Kristin Kirchner

Caravel Undergraduate Research Journal

The study at hand was designed to look into the issues of eating disorder awareness and dieting attitudes. Specifically, it was hypothesized that individuals with more knowledge of eating disorders would be less likely to believe in dieting. It was additionally hypothesized that there would be a difference in amount of eating disorder knowledge seen between pre-determined age groupings. This was hypothesized due to the nature of the inception of eating disorders as a clinical diagnosis. Eating disorders did not begin to be added as a category into the Diagnostic and Statistical Manual until the 80’s, suggesting that participants of …

Predicting Narcissism Through Social Media, Cameryn Freglette, Melanie Palomares

Caravel Undergraduate Research Journal

The objective of this study was to assess if narcissism can be predicted through social media behaviors such as frequency of posts, posting selfies, and social media presence on a variety of platforms. This study was conducted through a questionnaire related to social media use and a brief assessment from the Narcissistic Personality Inventory (NPI- 16). Results indicated that social media use per day was significantly different between people who post selfies and those who do not. Participants that scored higher for narcissism used social media less but posted significantly more selfies. Results were not significant in predicting narcissism through …

White Antiracists: Everyday Antiracism And White Fragility Among Racially Progressive White Americans, Buffy Renea Duncan, Jaclyn Wong Ph.D

Caravel Undergraduate Research Journal

Despite the abolition of slavery and Jim Crow laws, racial inequity persists. Bonilla-Silva (2017) suggests that colorblind racism, or the assertion that race does not matter for one’s life chances, has perpetuated anti-Black racial inequality since the Civil Rights Movement. Now, through antiracist efforts such as the Black Lives Matter (BLM) movement, White Americans are increasingly expanding their notions of racism to include the subtle, institutional racial discrimination associated with colorblind ideologies (Crass 2015). A rejection of “colorblind” thinking places Whites in a position to address systems of White supremacy, both in themselves and the world around them, but it …

Connecting On Campus: Exploring The Motivations And Behaviors Of College Students On Dating Apps, Emma Doyle, Melanie Palomares

Caravel Undergraduate Research Journal

Dating apps are increasingly popular among young people, including college students. However, these apps can be quite versatile, and there can be a number of reasons why a college student would use them, whether they are looking for a serious relationship, casual sex, or anything in between. Our study evaluated the intents, behaviors, and satisfaction of college students who used dating apps. Using Chi-Square and independent samples t-test analyses, results show that while satisfaction ratings were similar between men and women, more men use dating apps than women, which suggests that women might have a more negative perception of dating …

The Impact Of Weekly Workouts On Self-Reported Happiness Among College Students, Reid Davis, Melanie Palomares

Caravel Undergraduate Research Journal

College students are consistently at risk for depressive behaviors during a major time of habit transition (i.e., a time of gaining autonomy while developing their own lifestyle and health habits) and gaining in independence; this is met with only half of them not engaging in at least moderately vigorous exercise (Catellier 2013; Powell, 2019). The purpose of this study was to investigate the effects of types of exercise (cardio, weightlifting, and yoga/pilates) that undergraduate college students voluntarily engaged in on their subjective current and general happiness levels. There were 52 participants in the study, all undergraduates at the University of …

The Universe Under A Microscope, Claire Chabot

Caravel Undergraduate Research Journal

No abstract provided.