Digital Commons Network^™

Um To Lead State In New Nanobiotechnology Consortium, Clara Turnage

University of Mississippi News

OXFORD, Miss. – The National Science Foundation has awarded $7 million to fund a University of Mississippi-led initiative to make the Magnolia State a new hub for innovative health care solutions.

Pollution Characteristics Of Heavy Metals In Solid Waste Subgrade Filling Materials, Du Qianhui, Fu Wei, Zhang Junhui, Tang Qiang, Gu Fan

Journal of China & Foreign Highway

Using solid waste in the road engineering field for subgrade filling is an important approach for building green and low-carbon emission roads.However,most solid waste contains heavy metal pollutants to varying degrees,and heavy metals will be released under complex environments including rainfall infiltration and groundwater immersion,thereby causing pollution to the surrounding soil and groundwater if not handled properly.This paper reviewed the current status of research on four aspects,including the comprehensive use of solid waste materials in subgrade engineering,the leaching and migration behaviors of heavy metals in solid waste,and the prevention and control treatment of heavy metals in solid waste.It is found …

A Rapid Test Method For Deflection Of Small And Medium‑Span Bridges, Zhang Aipin, Ma Lindong, Chang Zhugang, Fan Zhihao

Journal of China & Foreign Highway

Bridge deflection response is on e of the most important indicators used for structural condition assessment of bridges.There are currently many methods and devices for deflection measurement,but they are not satisfying in terms of economy,applicability,and measurement accuracy at the same time.This paper proposed a rapid and highly accurate method for measuring mid-span deflection of small and medium-span bridges.By using the high accuracy of displacement transducers in direct contact measurement,an auxiliary measurement device was developed to transfer the deflection of the measurement points on the bridge to the displacement transducer in the form of a rigid connection,thus achieving accurate and dynamic …

Deflection Basin Characteristics Of Distressed Roads Under Moving Load, Cai Yingchun, Xie Shenjian

Journal of China & Foreign Highway

The deflection basins of roads under moving load imply the distress information of subgrade and pavement.Therefore,how to use the information of deflection basins under moving load to rapidly test road distresses non-destructively has received much attention.In this paper,the finite element model of semi-rigid base asphalt pavement was established.By setting different types and degrees of finite element distress models,the continuous changes of surface deflection basins under moving load were analyzed.The results show that when the load moves to the distress area,the center deflection value of surface deflection basins in each distress model will become larger.When transverse cracks appear in the pavement …

Real-World And Clinical Trial Outcomes In Large B-Cell Lymphoma With Axicabtagene Ciloleucel Across Race And Ethnicity, Frederick L Locke, Armin Ghobadi, Et Al.

2020-Current year OA Pubs

Axicabtagene ciloleucel (axi-cel) is an autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy approved for relapsed/refractory (R/R) large B-cell lymphoma (LBCL). Despite extensive data supporting its use, outcomes stratified by race and ethnicity groups are limited. Here, we report clinical outcomes with axi-cel in patients with R/R LBCL by race and ethnicity in both real-world and clinical trial settings. In the real-world setting, 1290 patients who received axi-cel between 2017 and 2020 were identified from the Center for International Blood and Marrow Transplant Research database; 106 and 169 patients were included from the ZUMA-1 and ZUMA-7 trials, respectively. Overall survival …

Detection Of Early-Stage Nash Using Non-Invasive Hyperpolarized 13c Metabolic Imaging, Cornelius Von Morze, Tyler Blazey, Ashley Shaw, William M Spees, Kooresh I Shoghi, Michael A Ohliger

2020-Current year OA Pubs

Non-alcoholic steatohepatitis (NASH) is characterized from its early stages by a profound remodeling of the liver microenvironment, encompassing changes in the composition and activities of multiple cell types and associated gene expression patterns. Hyperpolarized (HP)

Ddx181.1 Visual Identity Design Example 1, Sae University College

Exemplars

DDX181 Project 1 work from 24T2. Student exemplar.

A Nordic Perspective On Patient Online Record Access And The European Health Data Space, Maria Hägglund, Anna Kharko, Annika Bärkås, Charlotte Blease, Åsa Cajander, Catherine Desroches, Asbjørn Johansen Fagerlund, Josefin Hagström, Isto Huvila, Iiris Hörhammer, Bridget Kane, Gunnar O. Klein, Eli Kristiansen, Jonas Moll, Irene Muli, Hanife Rexhepi, Sara Riggare, Peeter Ross, Isabella Scandurra, Saija Simola, Hedvig Soone, Bo Wang, Maedeh Ghorbanian Zolbin, Rose Mharie Åhlfeldt, Sari Kujala, Monika Alise Johansen

School of Psychology

The Nordic countries are, together with the United States, forerunners in online record access (ORA), which has now become widespread. The importance of accessible and structured health data has also been highlighted by policy makers internationally. To ensure the full realization of ORA’s potential in the short and long term, there is a pressing need to study ORA from a cross-disciplinary, clinical, humanistic, and social sciences perspective that looks beyond strictly technical aspects. In this viewpoint paper, we explore the policy changes in the European Health Data Space (EHDS) proposal to advance ORA across the European Union, informed by our …

Employee Retention Strategies Of The U.S. Power Industry, Michael Robert Schulz

Walden Dissertations and Doctoral Studies

Employee turnover in the U.S. power industry continues to be a challenging issue. Leaders of U.S. power organizations tend to be concerned about employee turnover, which has a negative impact on productivity and profitability. Grounded in Herzberg’s hygiene-motivator theory, the purpose of this qualitative pragmatic inquiry was to identify and explore successful strategies that some U.S. power company leaders use to improve employee retention. The participants were seven business leaders from seven power companies across the Midwestern United States who successfully implemented strategies to improve employee retention. Data were collected using semistructured interviews and company website information. Through thematic analysis, …

Changes In Lean Body Mass With Glucagon-Like Peptide-1-Based Therapies And Mitigation Strategies, Ian J. Neeland

Faculty Scholarship

Weight loss induced by glucagon-like peptide-1 receptor agonists (GLP-1RAs) and dual glucagon-like peptide-1 receptor (GLP-1R)/glucose-dependent insulinotropic polypeptide receptor agonists is coming closer to the magnitudes achieved with surgery. However, with greater weight loss there is concern about potential side effects on muscle quantity (mass), health and function. There is heterogeneity in the reported effects of GLP-1-based therapies on lean mass changes in clinical trials: in some studies, reductions in lean mass range between 40% and 60% as a proportion of total weight lost, while other studies show lean mass reductions of approximately 15% or less of total weight lost. There …

Reporting Clinical Cases: Advancing Homoeopathy, One Case At A Time, Subhash Kaushik

Indian Journal of Research in Homoeopathy

Case reports have been invariably contributing to the research world in their own way. They remain a popular genre among the readers, especially the clinicians who lay their hands upon a clinical journal with an interest to pick new knowledge about a certain disease or a drug than to learn about new evidence generated through statistical calculations. Its presence in medical literature is reported to be quite ancient, with some evidence dated back to the Egyptian antiquity. In fact, a well-documented case report is a representative version of many similar clinical success stories.

Management Of Psychosis With Individualised Homoeopathic Medicines: A Case Series, Karunakara Moorthi, Susu Pertin, Mohan Narvelil Devasia

Indian Journal of Research in Homoeopathy

Background: Psychosis is a clinical syndrome. The main clinical signs of psychosis are delusion and hallucination. It is a crucial focus of diagnosis and treatment in neurologic and psychiatric practice since it functionally disturbs numerous psychiatric, neurodevelopmental, neurologic and medical diseases.

Case summary: The World Health Organization Quality of Life Scale and the Brief Psychiatric Rating Scale were used to evaluate the patients. The outcomes in all the cases suggested that homoeopathic treatment can play a significant role in easing psychotic symptoms and restoring the patient’s ability to understand. The most frequently prescribed medicines and potencies in these cases were …

Homoeopathic Treatment Of Oral Leucoplakia: A Case Report, Suraia Parveen, Zeeshan Ahmed

Indian Journal of Research in Homoeopathy

Introduction: Oral leucoplakia (OL), a premalignant lesion which is more frequently encountered in elderly people, is defined as a white lesion of the oral mucosa. Smoking is one of the most common risk factors. Conventionally, surgical excision is the most recommended treatment option for OL. Case Summary: A 55-year-old male presented with the complaint of a whitish lesion inside the left angle of the mouth (buccal mucosa) for the past 1½ years. The case was clinically diagnosed as OL. He was advised for surgical excision, but he preferred to go for homoeopathic treatment. Based on characteristic symptoms, repertorial analysis and …

Resolution Of Subdural Hygroma With Homoeopathy: A Case Report, Partha Pratim Pal, Tania Chatterjee

Indian Journal of Research in Homoeopathy

Introduction: Subdural hygroma (SDH) is a collection of cerebrospinal fluid in the subdural space which may be idiopathic, traumatic or post-surgical occurring mostly in elderly patients. Case Summary: A 42-year-old female reported an acute complaint of compressing headache. The headache persisted even after initial prescriptions of Ruta graveolens 30C and 200C, which did not alleviate the condition. Further evaluation was done with a computed tomography scan, which revealed left-sided SDH. Tuberculinum 1M was prescribed, but even though the pain subsided, profuse, watery discharge began to ooze from both the ears and nose, which eventually stopped spontaneously. After six months, the …

Management Of Post-Operative Breast Nodules With Homoeopathy: A Case Report, Nisanth K.M. Nambison, Smita N. Nambison, Abhishek D. Dwivedi, Nisha Chakravarty

Indian Journal of Research in Homoeopathy

Introduction: Palpable masses after mastectomy are commonly detected by patients or their physicians. Imaging of palpable masses is advised following a complete history and physical examination. This is a case of breast nodules occurring after the removal of cancerous tissue in the breast. Homoeopathy, with its holistic approach, can treat the disease by addressing its multifactorial origin.

Case summary: A 71-year-old female, diagnosed with post-operative breast nodules after surgical excision of mucinous carcinoma portion of the left breast, was treated with individualised homoeopathic treatment for six months with subsequent improvement. This case provides preliminary evidence for the potential usefulness of …

Homoeopathic Medicine Arsenic Album 200c In Treatment Of Plaque Psoriasis: A Case Report, Neha Nagar, Ravi K. Poswal, Ajay Kumar, Kanak Singhal

Indian Journal of Research in Homoeopathy

Introduction: Psoriasis is a non-communicable, chronic, mostly painful, disfiguring disease. It can have a negative impact on patients’ quality of life, which may occur at any age. The conventional treatment includes local and systemic therapies, as well as phototherapy. The need for treatment is usually lifelong as remission occurs quite frequently. Case Summary: We present here a case report of a 32-year-old woman with psoriatic lesions all over the body for 15 years with intolerable itching. The present case was completely cured after 1 year 6 months of regular treatment with individualised homoeopathic medicine without any adverse effects. After detailed …

Plantar Warts Treated With Homoeopathic Medicine Antimonium Crudum: A Case Report, Laijun Nahar, Ruma Debbarma

Indian Journal of Research in Homoeopathy

Introduction: Plantar warts are cutaneous lesions brought on by human papilloma virus infection. There is a range of alternative treatment available for it, including cryotherapy, chemical cauterisation, curettage, electrodessication and laser removal. However, a majority of these treatments can leave scars or may provide only temporary relief. Case Summary: A 19-year-old female presented with multiple, right-sided plantar warts and was successfully treated by a single, individualised homoeopathic medicine, Antimonium crudum 200C for two months. The improvement was assessed through photographs taken in subsequent follow-up visits. The case was monitored further for a period of six months without any recurrence. This …

Individualised Homoeopathic Treatment For Pilonidal Sinus: A Case Report, Sumit Paliwal, Laijun Nahar, Rachna Paliwal

Indian Journal of Research in Homoeopathy

Introduction: Pilonidal sinus is a very common inflammatory disease of the gluteal region. The most common site of occurrence is the natal cleft. It can cause discomfort, absence from work and social embarrassment. There is no single, widely accepted therapy available for this condition. In most cases, the treatment option for this disease is surgical intervention, but recurrences following surgery are common. Case Summary: A 15-year-old male patient reported discharge from the sinus cavity in the natal cleft along with pain and discomfort. Nitric acid, a homoeopathic medicine, was prescribed during the initial consultation and the patient was followed …

Diabetic Foot Ulcer Treated With The Homoeopathic Medicine Lachesis Mutus In Millesimal Potencies: A Case Report, Lalith Singh, Raja Manoharan, Niharika Shaw, Saleem Ansari

Indian Journal of Research in Homoeopathy

Introduction: Diabetic foot ulcer (DFU) is the most common neuropathic complication of diabetes. Uncontrolled diabetes and improper foot care lead to serious conditions like DFU from minor injuries. Regular dressing and proper foot care are required for its improvement. Patients are left with no other option than amputation of the limb. Dressing for a longer period seems not convenient and feasible at the patient’s end. DFU also has wet gangrene as one of its major complications. Case Summary: This case report presents a case of a diabetic patient complaining of a foot ulcer for the past nine years, following the …

Research Highlights, Shatakshi Bhardwaj, Archna Nagar

Indian Journal of Research in Homoeopathy

Research Highlights

Quantifying The Dosimetric Impact Of Proton Range Uncertainties On Rbe-Weighted Dose Distributions In Intensity-Modulated Proton Therapy For Bilateral Head And Neck Cancer, Suresh Rana, Noufal Manthala Padannayil, Hina Saeed, Michael Kasper

All Publications

Background: In current clinical practice, intensity-modulated proton therapy (IMPT) head and neck cancer (HNC) plans are generated using a constant relative biological effectiveness (cRBE) of 1.1. The primary goal of this study was to explore the dosimetric impact of proton range uncertainties on RBE-weighted dose (RWD) distributions using a variable RBE (vRBE) model in the context of bilateral HNC IMPT plans.

Methods: The current study included the computed tomography (CT) datasets of ten bilateral HNC patients who had undergone photon therapy. Each patient's plan was generated using three IMPT beams to deliver doses to the CTV_High and CTV_Low for doses …

Broadened Positive And Emotion Congruent Attentional Biases And Emotion Regulation, Michael Mctighe

Theses

Attentional processes or concentration of mental faculties is a vast area of research in the cognitive sciences that is complicated by an abundance of other variables. Evidence overwhelming suggests that exogenous attention is biased toward emotional stimuli. Prevailing theories suggest that positive emotions can improve attentional processes, and that a participant’s emotional state can lead people to better attend to congruent information. Systems associated with emotion regulation overlap with processes related to biased attention. This study sought to further explore the theories of broaden and build, and emotion congruence, while also exploring how emotion regulation influences various types of attentional …

Roles Of Mitochondrial Chchd2 And Gpcr-Associated Β-Arrestin2 In The Pathogenesis Of Lewy Body Disorders, Teresa R. Kee

USF Tampa Graduate Theses and Dissertations

Coiled-coil-helix-coiled-coil-helix domain containing 2 (CHCHD2) is a mitochondrial protein that plays important roles in cristae structure, oxidative phosphorylation, and apoptosis. Multiple mutations in CHCHD2 have been associated with Lewy body disorders (LBDs), such as Parkinson’s disease (PD) and dementia with Lewy bodies (DLB), with the CHCHD2T61I mutation being the most widely studied. We generated the first transgenic mouse models expressing human CHCHD2WT and the PD-linked CHCHD2T61I mutation driven by the mPrP promoter. CHCHD2T61I Tg, but not CHCHD2WT Tg mice exhibit perinuclear mitochondrial aggregates, neuroinflammation, and have impaired long-term synaptic plasticity associated with synaptic dysfunction. Dopaminergic neurodegeneration, a hallmark of PD, …

Infantile Haemangioma Treated With Homoeopathy: A Case Report, Harpreet Kaur, Ravinder Singh

Indian Journal of Research in Homoeopathy

Introduction: Infantile haemangiomas (IH) are common benign tumours of infancy. Approximately, one in ten infants gets affected. The male-tofemale ratio is variable, with some reports suggesting that females are more prone than males. In India, the prevalence of IH in various studies has been reported as varying from 0.1% to 0.28%. The head and neck are the regions where most of the haemangiomas are located. The lesions are apparent soon after birth and are followed by rapid proliferation during the first year of life and a gradual involution occurs over the next five to ten years. Case summary: …

Management Of Tinea Corporis With The Minimum Doses Of Homoeopathic Nosode Psorinum: A Case Report, Punam Kumari, Shivam Kumar, Renu Verma

Indian Journal of Research in Homoeopathy

Introduction: Tinea corporis (TC) is the most common superficial fungal infection of the skin that invades and grows in dead keratin. The topical treatment causes suppression of TC and with the effect of it, a repeated episode of relapse occurs, which hampers the quality of life of the patient. Case Summary: This case of TC, with extensive spread on the body, demonstrates the curative effect of homoeopathic medicine with minimum dosage. A 64-year-old male diagnosed with TC was treated successfully with individualised homoeopathic medicine for seven months. The outcome was assessed through before-and-after-treatment photographs. Dermatology Life Quality Index (DLQI) score …

A Case Report Of Attention Deficit Hyperactivity Disorder In Preschool Children Treated With Individualised, Constitutional Homoeopathic Medicine, Karunakara Moorthi, Lalitha K S

Indian Journal of Research in Homoeopathy

Introduction: Attention deficit hyperactivity disorder (ADHD) is a neuropsychiatric disorder affecting children of all ages, including preschoolers, adolescents, and adults worldwide. ADHD patients often face challenges in academic and social settings. Notably, pre-school children are more likely to exhibit hyperactive-impulsive symptoms than school-age children. Research on treating pre-schoolers with ADHD is limited compared to older children. This case report demonstrates the treatment of ADHD in pre-schoolers using individualised homoeopathic remedies. Case Summary: A 4-year-old boy presented with a 2-year history of symptoms, such as restlessness, easy distractibility and aggressive behaviour. After assessing the case, the institute’s psychiatric consultant diagnosed it …

Laryngopharyngeal Reflux Disease With Vocal Cord Oedema Treated With Individualised Homoeopathic Medicine: A Case Report, Partha Pratim Pal, Laijun Nahar

Indian Journal of Research in Homoeopathy

Introduction: The diagnosis of laryngopharyngeal reflux disease (LPRD) is still ambiguous due to limited and cumbersome diagnostic standards. To achieve regression of both symptoms and laryngeal findings due to LPRD, it typically requires more vigorous and sustained treatment. In certain patients with chronic acid or non-acid reflux, surgery may be helpful. Case Summary: This is the case of a 68-year-old man who was diagnosed with LPRD and had vocal cord oedema. Individualised homoeopathic medicine, Natrum sulphuricum, was prescribed, and the patient improved steadily in terms of signs and symptoms and had no further complaints at the end of 16 …

Cutaneous Warts Treated With A Single Dose Of The Homoeopathic Medicine Carcinosin 200c: An Evidence-Based Case Report, Sivakumar K, Mamatha Mohan

Indian Journal of Research in Homoeopathy

Introduction: Cutaneous warts are hyperkeratotic protrusions over the skin caused by human papilloma virus (HPV). These are common throughout the world. Cutaneous warts can occur at any age but are unusual in early childhood and infancy. Warts are often diagnosed clinically on physical examination, but some dysplastic lesions may require laboratory confirmation of HPV. Spontaneous clearance is not always possible, and offering a reliable prognosis to the individual case is impossible. Even though warts are frequently encountered in the day-to-day practice of homoeopathy, and the results are promising, there are limited research studies available in the online database. Case Summary: …

Successfully Initiating An Escalation Of Care In Acute Ward Settings—A Qualitative Observational Study, J. Ede, B. Kent, P. Watkinson, R. Endacott

School of Nursing and Midwifery

Aims: To address knowledge gaps by (i) developing a theoretical understanding of escalation and (ii) identifying escalation success factors. Design: Non-participant observations were used to examine deteriorating patient escalation events. Methods: Escalation event data were collected by a researcher who shadowed clinical staff, between February 16th 2021 and March 17th 2022 from two National Health Service Trusts. Events were analysed using Framework Analysis. Escalation tasks were mapped using a Hierarchical Task Analysis diagram and data presented as percentages, frequency and 95% CI. Results: A total of 38 observation sessions were conducted, totaling 105 h, during which 151 escalation events were …

Emotional Intelligence And Critical Thinking In Practical Nursing Students: A Quantitative Study, Jennifer L. Knaack

Dissertations

The aim of this study was to understand if emotional intelligence was predictive of critical thinking in practical nursing students enrolled in a practical nursing program. The literature shows that nursing students' emotional intelligence and critical thinking directly affect student success; however, there is limited research focused on emotional intelligence and its predictability of critical thinking in practical nursing students enrolled in a practical nursing program. This quantitative, predictive study was designed to fill the gap in the literature on the relationship between emotional intelligence and critical thinking in nursing students enrolled in practical nursing programs.