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The Impact Of Incorporating Technology On Student Engagement And Achievement In An Elementary Classroom, Amanda Donahoo Jul 2024

The Impact Of Incorporating Technology On Student Engagement And Achievement In An Elementary Classroom, Amanda Donahoo

Master's Theses & Capstone Projects

Schools across the country face distracted students who struggle to focus, leading to less engagement and lower academic success. Research has shown that student learning outcomes are often influenced by their level of engagement and that technology can be utilized as a powerful tool for motivation. This study aims to identify the effectiveness of incorporating educational technology, such as one-to-one computers, tablets, and interactive lessons, to increase student engagement and academic achievement so that elementary schools will benefit. Based on a literature review on technology’s impact on education, an online survey was distributed to elementary teachers at a rural, public …


Improving Student Outcomes With Project-Based Learning, Tyler Archer Jul 2024

Improving Student Outcomes With Project-Based Learning, Tyler Archer

Master's Theses & Capstone Projects

This capstone project analyzes the impact of Project-Based Learning (PBL) on student outcomes at Indianola High School, specifically focusing on student engagement, self-efficacy, and academic achievement in a U.S. History classroom. Recent declines in student performance, specifically in math and reading, indicate that changes are needed. This study examines the potential of PBL to increase content mastery, critical thinking, and historical inquiry skills among high school students. Through a comprehensive literature review and an action plan created for the specific needs of Indianola High School, this research identifies key benefits and challenges associated with PBL. The research suggests that PBL …


Building School Culture Improves Students’ Mental Health, Katie Henrichs Jul 2024

Building School Culture Improves Students’ Mental Health, Katie Henrichs

Master's Theses & Capstone Projects

Students are experiencing a rise in mental health challenges, which can have a negative impact on academic performance, lead to an increase in undesirable behaviors, and result in attendance issues. Research shows that creating a positive school community can contribute to the well-being of students. A school improvement plan has been developed to foster a sense of community at Loess Hills. Both students and staff will be involved in surveys, focus groups, and the inclusion of a social-emotional curriculum. Promoting a positive culture where students can thrive can be achieved by raising awareness and providing support for young people dealing …


Open Access Publishing Support, Chad Metz Jul 2024

Open Access Publishing Support, Chad Metz

TMC Library Newsletter (2015-)

Check the recently updated Open Access Publishing Support LibGuide for the most recent information about scholarly publications. This newly revamped LibGuide is a great resource to learn about Read and Publish. Read and Publish is also known as a transformative agreement, it is an open access (OA) model that bundles payment for reading access and payment for publishing into a single contract.


Teaching In Clinics: Open Access Journal In Digital Commons, Alice Sherwood Jul 2024

Teaching In Clinics: Open Access Journal In Digital Commons, Alice Sherwood

TMC Library Newsletter (2015-)

Teaching in Clinics is one of the open access, peer-reviewed online academic journals published semiannually in the Digital Commons@TMC. The journal aims to encourage researchers and educators to share their studies for implementing novel teaching methods. In addition to excellence of teaching, Teaching in Clinics seeks to bring academic discussions of the incoming or present challenges in health and education policies. The most recent issue launched late last month.


Legal Support For Local Election Officials, Rebecca Green Jul 2024

Legal Support For Local Election Officials, Rebecca Green

Faculty Publications

Local election officials (“LEOs”) face enormous pressure. They must administer elections when a wide swath of the American public has grown mistrustful of their work; they increasingly face ominous personal attacks and threats; they cope with chronic underfunding of elections; and they must navigate frequent changes in the law governing elections. Lawyers provide a critical avenue of support for local election officials. They provide guidance on how to implement legislative mandates and judicial orders; they anticipate and prevent disputes from arising; and they represent election officials when they or their offices are sued—a more common occurrence today than ever. Although …


Enhancement Of Polytetrafluoroethylene-Polyvinyl Alcohol Nanofibers Triboelectric Effect With Carboxylic Functionalized Multiwalled Carbon Nanotubes Coating, Fernando Viesca Jul 2024

Enhancement Of Polytetrafluoroethylene-Polyvinyl Alcohol Nanofibers Triboelectric Effect With Carboxylic Functionalized Multiwalled Carbon Nanotubes Coating, Fernando Viesca

Theses and Dissertations

In this study, we fabricated a TENG using Forcespinning® (FS) Polytetrafluoroethylene microfibers (FS-PTFE-MFs) and Electrospun (ES) Polyvinyl alcohol nanofibers (ES-PVA-NFs). The FS-PTFE-MFs were physically linked with functionalized carboxylic multiwall carbon nanotubes (MWCNTs-COOH) employing water dispersions. MWCNTs-COOH were dispersed using three different surfactants: Sodium Dodecyl Sulfate (SDS), Sodium dodecylbenzenesulfonate (SDBS), and Triton X-100 (TX-100). Coated FS-PTFE-MFs were then characterized using a field emission scanning electron microscope (FESEM) with an energy dispersive X-ray spectroscopy (EDS) attachment and Fourier-transform infrared spectroscopy (FTIR). While no significant difference in performance was observed with different surfactants, electrical results of the TENG recorded a notable enhancement of …


Greenhouse Gas Emissions From Urban Lawn Soil Amended With Biochar And Compost Under Contrasting Redox Conditions, Angel Salinas Jul 2024

Greenhouse Gas Emissions From Urban Lawn Soil Amended With Biochar And Compost Under Contrasting Redox Conditions, Angel Salinas

Theses and Dissertations

Green fields around the world are being converted to urban land uses to cope with population growth and urbanization. The objective of this study was to investigate how urban lawn soils can contribute to greenhouse gas (GHG) emissions in relation to soil saturation-drainage cycles. We measured carbon dioxide (CO2), methane (CH4), and nitrous oxide (N2O) emissions as well as redox potential (Eh) from garden soils amended with biochar, compost, or biochar + compost under a mesocosm scale. Bermuda turfgrass seed was seeded in each column (5-gallon bucket) and three water saturation conditions (half-saturated, full-saturated, and unsaturated soils) were maintained for …


Lilrb4 On Multiple Myeloma Cells Promotes Bone Lesion By P-Shp2/Nf-Κb/Relt Signal Pathway, Hongying Wang, Lei Wang, Huiwen Luan, Jing Xiao, Zhiling Zhao, Pengfei Yu, Mi Deng, Yifan Liu, Shuhao Ji, Junjie Ma, Yan Zhou, Jiashen Zhang, Xianhui Meng, Juan Zhang, Xinyu Zhao, Chunling Li, Fangmin Li, Dapeng Wang, Shujuan Wei, Lijun Hui, Siman Nie, Changzhu Jin, Zhiqiang An, Ningyan Zhang, Yaopeng Wang, Cheng Cheng Zhang, Zunling Li Jul 2024

Lilrb4 On Multiple Myeloma Cells Promotes Bone Lesion By P-Shp2/Nf-Κb/Relt Signal Pathway, Hongying Wang, Lei Wang, Huiwen Luan, Jing Xiao, Zhiling Zhao, Pengfei Yu, Mi Deng, Yifan Liu, Shuhao Ji, Junjie Ma, Yan Zhou, Jiashen Zhang, Xianhui Meng, Juan Zhang, Xinyu Zhao, Chunling Li, Fangmin Li, Dapeng Wang, Shujuan Wei, Lijun Hui, Siman Nie, Changzhu Jin, Zhiqiang An, Ningyan Zhang, Yaopeng Wang, Cheng Cheng Zhang, Zunling Li

The Brown Foundation: Institute of Molecular Medicine

Background: Leukocyte Ig-like receptor B family 4 (LILRB4) as an immune checkpoint on myeloid cells is a potential target for tumor therapy. Extensive osteolytic bone lesion is the most characteristic feature of multiple myeloma. It is unclear whether ectopic LILRB4 on multiple myeloma regulates bone lesion.

Methods: The conditioned medium (CM) from LILRB4-WT and -KO cells was used to analyze the effects of LILRB4 on osteoclasts and osteoblasts. Xenograft, syngeneic and patient derived xenograft models were constructed, and micro-CT, H&E staining were used to observe the bone lesion. RNA-seq, cytokine array, qPCR, the activity of luciferase, Co-IP and western blotting …


Clinical Presentation And Outcomes Of Care In Adults With Diabetic Ketoacidosis Pre-Covid-19 And During-Covid-19 At A Tertiary, Referral Hospital In Nairobi, Kenya, Sairabanu Sokwalla, Jasmit Shah, Sangeeta Chauhan, Reena Shah, Salim Surani, Eric Njenga, Nancy Kunyiha Jul 2024

Clinical Presentation And Outcomes Of Care In Adults With Diabetic Ketoacidosis Pre-Covid-19 And During-Covid-19 At A Tertiary, Referral Hospital In Nairobi, Kenya, Sairabanu Sokwalla, Jasmit Shah, Sangeeta Chauhan, Reena Shah, Salim Surani, Eric Njenga, Nancy Kunyiha

Internal Medicine, East Africa

Background: Prognosis of DKA has improved over time with the availability of evidence-based protocols and resources. However, in Kenya, there are limited resources for the appropriate diagnosis and management of DKA, mostly limited to tertiary-level referral facilities. This study aimed to review the clinical presentation, management, and outcomes of adult patients admitted with DKA and assess differences in these parameters before and during the COVID-19 pandemic.

Methods: This was a retrospective study of DKA admissions from January 2017 to December 2021. Patient data were retrieved from the medical records department using ICD-10 codes, and individual details were abstracted on clinical …


Open-Label, Dose-Escalation Fight-101 Study Of Pemigatinib Combined With Targeted Therapy, Chemotherapy, Or Immunotherapy In Patients With Advanced Malignancies, Mansoor Saleh, Minal Barve, Vivek Subbiah, Kyriakos Papadopoulos, Daniel Morgensztern, Niharika Mettu, Sameek Roychowdhury, Iben Spanggaard, Maria Luisa Veronese, Chenwei Tian Jul 2024

Open-Label, Dose-Escalation Fight-101 Study Of Pemigatinib Combined With Targeted Therapy, Chemotherapy, Or Immunotherapy In Patients With Advanced Malignancies, Mansoor Saleh, Minal Barve, Vivek Subbiah, Kyriakos Papadopoulos, Daniel Morgensztern, Niharika Mettu, Sameek Roychowdhury, Iben Spanggaard, Maria Luisa Veronese, Chenwei Tian

Haematology and Oncology, East Africa

Background Pemigatinib is an oral, potent, selective fibroblast growth factor receptor (FGFR) 1-3 inhibitor. FIGHT-101, a three-part, open-label, first-in-human, phase I/II study (NCT02393248), evaluated pemigatinib in patients with advanced solid tumors. In parts 1 and 2, pemigatinib monotherapy had a manageable safety profile and antitumor activity in FGFR-altered tumors. Part 3 (pemigatinib combination therapies) results are presented here.

Patients and methods Patients received 9, 13.5, or 20 mg oral once-daily pemigatinib on continuous or intermittent schedules with gemcitabine and cisplatin (pemi/gem/cis), docetaxel (pemi/doc), trastuzumab (pemi/tras), pembrolizumab (pemi/pembro), or retifanlimab (pemi/reti) irrespective of whether the tumor was confirmed as FGFR altered. …


Transcriptional Investigations Into Neonatal Gut Development Related To Early Feeding, Sierra Keele, Laurel Nuñez, Yimin Chen, Matayah Fox, Jordan Richter, Ben Worthley, Bethaney Fehrenkamp Jul 2024

Transcriptional Investigations Into Neonatal Gut Development Related To Early Feeding, Sierra Keele, Laurel Nuñez, Yimin Chen, Matayah Fox, Jordan Richter, Ben Worthley, Bethaney Fehrenkamp

Idaho Conference on Undergraduate Research

Introduction: While numerous correlational studies suggest that human milk (HM) optimizes infant gut development, little is known about the physiological process. To investigate HM's protective mechanisms for intestinal development, we used the neonatal piglet model. The recommended time to exclusively breastfeed an infant is six months, which is equivalent to one month in piglets. We hypothesized that HM-fed piglets would show increased paracellular junctions and reduced inflammatory markers in the intestines compared to infant formula (IF)-fed piglets.

Methods: We reared littermate Yorkshire-duroc piglets for 28 days, assigning them to HM-fed (n=6) and IF-fed (n=6) groups, alongside controls reared on sow’s …


2024 July, Morehead State University. Office Of Communications & Marketing. Jul 2024

2024 July, Morehead State University. Office Of Communications & Marketing.

Morehead State Press Release Archive, 1961 to the Present

Press releases for July of 2024.


Speaking Up: A Narrative Inquiry Of International Students' Active Verbal Engagement In Classrooms At A Southeastern American University, Sabrina Xiaoyan Liu Jul 2024

Speaking Up: A Narrative Inquiry Of International Students' Active Verbal Engagement In Classrooms At A Southeastern American University, Sabrina Xiaoyan Liu

Graduate Theses and Dissertations (2019 - present)

This qualitative narrative research investigated successful cases of international students who actively verbally participate and speak up during academic or coursework discussions in the classrooms. More specifically, the aim of this narrative inquiry was to capture the lived and living experiences of English language learners (ELLs) navigating American mainstream classrooms. Moreover, this qualitative study explored how they perceive the impact of their English language proficiency on their verbal engagement during class. I recruited participants through the international office at a southeastern university in the United States. After an initial phone screening session to verify that each interested participant met the …


Representations Of Violence Against Native American Women, Christine York Jul 2024

Representations Of Violence Against Native American Women, Christine York

Graduate Theses and Dissertations (2019 - present)

It is the aim of this study to provide detailed attention to the representation of violence against Native American women throughout American films and literature. Native American women have been persecuted against since the times of colonization; however, there has been a recent uptake in this crime. This crime has been seen throughout many forms of art, but has not often been a focal point to these artforms. In order to argue that the violence these women experience needs to be central to the texts they are seen in, a comparison between three different texts is imperative. These texts are …


Optimizing Attention Bias Training For Depression, Bridget R. Kennedy Jul 2024

Optimizing Attention Bias Training For Depression, Bridget R. Kennedy

Clinical Psychology Dissertations

Depression has been associated with a negative attention bias. Attention bias modification (ABM) interventions among individuals with depression have demonstrated promising but inconsistent findings in reducing negative attention bias and decreasing depression symptoms. These inconsistent results may be partly due to impaired attention functioning that is common in depression. Mindfulness has demonstrated attention benefits, which may enhance the ability for individuals with depression to benefit from ABM interventions. This study aimed to explore the efficacy of a train-positive dot-probe task ABM intervention when compared to a placebo dot-probe task, both preceded by a series of brief mindfulness activities, among a …


Genetic Correlations Between Liver Fat Content, Metabolic Health, And Adiposity Distribution In The Fels Longitudinal Study, Ariana L Garza, Miryoung Lee, John Blangero, Cici X Bauer, Stefan A Czerwinski, Audrey C Choh Jul 2024

Genetic Correlations Between Liver Fat Content, Metabolic Health, And Adiposity Distribution In The Fels Longitudinal Study, Ariana L Garza, Miryoung Lee, John Blangero, Cici X Bauer, Stefan A Czerwinski, Audrey C Choh

Faculty, Staff and Student Publications

Background and aims: Hepatic steatosis is known to be heritable, but its genetic basis is mostly uncharacterized. Steatosis is associated with metabolic and adiposity features; recent studies hypothesize that shared genetic effects between these traits could account for some of the unexplained heritability. This study aimed to quantify these genetic associations in a family-based sample of non-Hispanic white adults.

Methods and results: 704 participants (18-95 years, 55.8% female) from the Fels Longitudinal Study with an MRI assessment of liver fat were included. Quantitative genetic analyses estimated the age- and sex-adjusted heritability of individual traits and the genetic correlations within trait …


Association Between Participation And Satisfaction With Life Over Time In Older Adults With Traumatic Brain Injury: A Tbi Model Systems Study, Zinat Taiwo, Angelle M Sander, Shannon B Juengst, Xiangyi Liu, Luis Leon Novelo, Flora M Hammond, Therese M O'Neil-Pirozzi, Paul B Perrin, Nicholas Gut Jul 2024

Association Between Participation And Satisfaction With Life Over Time In Older Adults With Traumatic Brain Injury: A Tbi Model Systems Study, Zinat Taiwo, Angelle M Sander, Shannon B Juengst, Xiangyi Liu, Luis Leon Novelo, Flora M Hammond, Therese M O'Neil-Pirozzi, Paul B Perrin, Nicholas Gut

Faculty, Staff and Student Publications

Objective: To examine the association between participation and satisfaction with life at 1, 2, 5, and 10 years after traumatic brain injury (TBI) in older adults.

Setting: Community.

Participants: Participants ( N = 2362) who sustained complicated mild to severe TBI, requiring inpatient rehabilitation, at age 60 years or older and had follow-up data on participation and satisfaction with life for at least 1 follow-up time point across 1, 2, 5, and 10 years. Age at each time period was categorized as 60 to 64 years, 65 to 75 years, and 75 years or older.

Design: Secondary data analysis of …


Dermoscopy Of A Solitary Circumscribed Neuroma Of The Lip Vermillion, Cody M Atack, Victoria A Mañón, Arthur L Taguchi, Nadarajah Vigneswaran, Jose M Marchena Jul 2024

Dermoscopy Of A Solitary Circumscribed Neuroma Of The Lip Vermillion, Cody M Atack, Victoria A Mañón, Arthur L Taguchi, Nadarajah Vigneswaran, Jose M Marchena

Faculty, Staff and Student Publications

No abstract provided.


A Cytomics-On-A-Chip Platform And Diagnostic Model Stratifies Risk For Oral Lichenoid Conditions, Michael P Mcrae, Kritika Srinivasan Rajsri, A Ross Kerr, Nadarajah Vigneswaran, Spencer W Redding, Malvin Janal, Stella K Kang, Leena Palomo, Nicolaos J Christodoulides, Meena Singh, Jeffery Johnston, John T Mcdevitt Jul 2024

A Cytomics-On-A-Chip Platform And Diagnostic Model Stratifies Risk For Oral Lichenoid Conditions, Michael P Mcrae, Kritika Srinivasan Rajsri, A Ross Kerr, Nadarajah Vigneswaran, Spencer W Redding, Malvin Janal, Stella K Kang, Leena Palomo, Nicolaos J Christodoulides, Meena Singh, Jeffery Johnston, John T Mcdevitt

Faculty, Staff and Student Publications

Objective: A small fraction of oral lichenoid conditions (OLC) have potential for malignant transformation. Distinguishing OLCs from other oral potentially malignant disorders (OPMDs) can help prevent unnecessary concern or testing, but accurate identification by nonexpert clinicians is challenging due to overlapping clinical features. In this study, the authors developed a 'cytomics-on-a-chip' tool and integrated predictive model for aiding the identification of OLCs.

Study design: All study subjects underwent both scalpel biopsy for histopathology and brush cytology. A predictive model and OLC Index comprising clinical, demographic, and cytologic features was generated to discriminate between subjects with lichenoid (OLC+) (N = 94) …


July 2024, Swosu Bulldog Wellness Committee Jul 2024

July 2024, Swosu Bulldog Wellness Committee

SWOSU BULLDOG WELLNESS

UV Safety Awareness & Parks and Recreation Month


As many of us are enjoying those warm rays this summer, we must remember to protect our skin and eyes from the damaging effects of the sun.


Financial Incentives For Smoking Cessation Among Socioeconomically Disadvantaged Adults: A Randomized Clinical Trial, Darla E Kendzor, Michael S Businelle, Summer G Frank-Pearce, Joseph J C Waring, Sixia Chen, Emily T Hébert, Michael D Swartz, Adam C Alexander, Munjireen S Sifat, Laili Kharazi Boozary, David W Wetter Jul 2024

Financial Incentives For Smoking Cessation Among Socioeconomically Disadvantaged Adults: A Randomized Clinical Trial, Darla E Kendzor, Michael S Businelle, Summer G Frank-Pearce, Joseph J C Waring, Sixia Chen, Emily T Hébert, Michael D Swartz, Adam C Alexander, Munjireen S Sifat, Laili Kharazi Boozary, David W Wetter

Faculty, Staff and Student Publications

IMPORTANCE: Socioeconomically disadvantaged individuals (ie, those with low socioeconomic status [SES]) have difficulty quitting smoking and may benefit from incentive-based cessation interventions.

OBJECTIVES: To evaluate the impact of incentivizing smoking abstinence on smoking cessation among adults with low SES.

DESIGN, SETTING, AND PARTICIPANTS: This study used a 2-group randomized clinical trial design. Data collection occurred between January 30, 2017, and February 7, 2022. Participants included adults with low SES who were willing to undergo smoking cessation treatment. Data were analyzed from April 18, 2023, to April 19, 2024.

INTERVENTIONS: Participants were randomized to usual care (UC) for smoking cessation (counseling …


Urban Soil Compaction Remediation By Shallow Tillage And Compost In Hydroseeded Lawn, James Jihoon Kang, Adam Flores, Engil Isadora Pujol Pereira, Jungseok Ho Jul 2024

Urban Soil Compaction Remediation By Shallow Tillage And Compost In Hydroseeded Lawn, James Jihoon Kang, Adam Flores, Engil Isadora Pujol Pereira, Jungseok Ho

School of Earth, Environmental, & Marine Sciences Faculty Publications

Construction activities often involve removal of topsoil and compaction of the exposed soil by heavy equipments. Such compacted soils with low organic matter can lead to low infiltration and poor vegetation establishment. The objective of this study was to investigate the efficacy of tillage (shallow till) and compost on soil physical and biological properties in a hydroseeded lawn as a post-construction best management practice for soil compaction remediation. The experimental site received a total of four land treatments in five replicated trials and it was hydroseeded with common Bermuda grass: 1) No Tillage + Compost (NT-C), 2) No Tillage + …


The Unraveling Of The Federal Home Loan Banks, Kathryn Judge Jul 2024

The Unraveling Of The Federal Home Loan Banks, Kathryn Judge

Faculty Scholarship

The Federal Home Loan Bank system is a $1.3 trillion government-sponsored enterprise that operates primarily for the benefit of member financial institutions. Federal Home Loan Bank members enjoy generous dividends and ready access to fresh liquidity. The biggest beneficiaries are the biggest users of the system, including the largest banks and insurance companies in the country and banks facing financial distress. This essay explains the original aims of the Federal Home Loan Bank system, how the system fulfilled those aims quite successfully for decades following its creation in 1932 and how the system evolved to serve primarily private aims. By …


Sex Differences In Spontaneous Respiratory Recovery In Chronic Hemisection, Taylor C. Holmes, Nicole M. Popp, Carley F. Hintz, Isabell Dobrzycki, Carolyn J. Schmitz, Kaylyn A. Schwichtenberg, Elisa J. Gonzalez-Rothi, Christopher W. Sundberg, Kristi A. Streeter Jul 2024

Sex Differences In Spontaneous Respiratory Recovery In Chronic Hemisection, Taylor C. Holmes, Nicole M. Popp, Carley F. Hintz, Isabell Dobrzycki, Carolyn J. Schmitz, Kaylyn A. Schwichtenberg, Elisa J. Gonzalez-Rothi, Christopher W. Sundberg, Kristi A. Streeter

Physical Therapy Faculty Research and Publications

Respiratory deficits after C2 hemisection (C2Hx) have been well documented through single-sex investigations. Although ovarian sex hormones enable enhanced respiratory recovery observed in females 2 wk post-C2Hx, it remains unknown if sex impacts spontaneous respiratory recovery at chronic time points. We conducted a longitudinal study to provide a comprehensive sex-based characterization of respiratory neuromuscular recovery for 8 wk after C2Hx. We recorded ventilation and chronic diaphragm electromyography (EMG) output in awake, behaving animals, phrenic motor output in anesthetized animals, and performed diaphragm muscle histology in chronically injured male and female rodents. Our results show that females expressed a greater recovery …


Noninvasive Estimation Of Skeletal Muscle Oxygen Consumption Rate And Microvascular Reactivity In Chronic Stroke Survivors Using Near-Infrared Spectroscopy, Allison S. Hyngstrom, Jennifer N. Nguyen, David D. Gutterman, Brian D. Schmit, Emilie A. Klevenow, Matthew J. Durand Jul 2024

Noninvasive Estimation Of Skeletal Muscle Oxygen Consumption Rate And Microvascular Reactivity In Chronic Stroke Survivors Using Near-Infrared Spectroscopy, Allison S. Hyngstrom, Jennifer N. Nguyen, David D. Gutterman, Brian D. Schmit, Emilie A. Klevenow, Matthew J. Durand

Physical Therapy Faculty Research and Publications

Understanding post-stroke changes in skeletal muscle oxidative metabolism and microvascular reactivity could help create therapeutic targets that optimize rehabilitative interventions. Due to disuse atrophy, we hypothesized that basal muscle oxygen consumption rate and microvascular endothelial function would be impaired in the tibialis anterior (TA) muscle of the affected leg of chronic stroke survivors compared with the nonaffected leg and versus matched controls. Fifteen chronic stroke survivors (10 females) and 15 matched controls (9 females) completed this study. A near-infrared spectroscopy oximeter measured tissue oxygen saturation (StO2) of the TA in both legs of stroke survivors and the dominant …


Reduced Oxygen Desaturation In The Vastus Lateralis Of Chronic Stroke Survivors During Graded Muscle Contractions, Allison S. Hyngstrom, Jennifer N. Nguyen, Spencer A. Murphy, Stephanie C. Raab, Brian D. Schmit, David D. Gutterman, Matthew J. Durand Jul 2024

Reduced Oxygen Desaturation In The Vastus Lateralis Of Chronic Stroke Survivors During Graded Muscle Contractions, Allison S. Hyngstrom, Jennifer N. Nguyen, Spencer A. Murphy, Stephanie C. Raab, Brian D. Schmit, David D. Gutterman, Matthew J. Durand

Physical Therapy Faculty Research and Publications

Background

Few studies have examined changes in skeletal muscle physiology post-stroke. This study examined changes in tissue oxygen saturation (StO2) of the vastus lateralis (VL) muscle of stroke survivors and age-matched control participants during maximal and submaximal isometric contractions of the knee extensor muscles.

Objectives

We hypothesized that tissue oxygen desaturation (ΔStO2) during knee extensor muscle contractions would be less in the VL in the paretic vs. the non-paretic and control legs.

Methods

Ten chronic stroke survivors (>6 months post-stroke) with lower extremity muscle weakness and 10 age-matched controls completed this prospective cohort study. Maximum …


Prolonged Quadriceps Latency During Gait Early After Anterior Cruciate Ligament Injury Predicts Radiographic Knee Osteoarthritis 6-Years After Anterior Cruciate Ligament Reconstruction, Naoaki Ito, Jacob J. Capin, Elanna Arhos, Elizabeth Wellsandt, Ryan T. Pohlig, Thomas S. Buchanan, Lynn Snyder-Mackler Jul 2024

Prolonged Quadriceps Latency During Gait Early After Anterior Cruciate Ligament Injury Predicts Radiographic Knee Osteoarthritis 6-Years After Anterior Cruciate Ligament Reconstruction, Naoaki Ito, Jacob J. Capin, Elanna Arhos, Elizabeth Wellsandt, Ryan T. Pohlig, Thomas S. Buchanan, Lynn Snyder-Mackler

Physical Therapy Faculty Research and Publications

The purpose was to explore quadriceps electromechanical function (quadriceps latency) during gait after anterior cruciate ligament injury as a predictor for radiographic knee osteoarthritis 6-years after anterior cruciate ligament reconstruction. Change in latency after preoperative physical therapy was also examined.

Methods

Quadriceps latency (time between peak knee moment and quadriceps electromyography) was calculated before preoperative physical therapy (2.4 [0.5–7.5] months after anterior cruciate ligament injury) and after preoperative physical therapy in 24 athletes. Participants were dichotomized into osteoarthritis (Kellgren and Lawrence grade ≥ 2) and non-osteoarthritis groups at 6-years. Forward selection logistic repression was performed using z-score normalized quadriceps latency …


Of Light And Shadows: Buddhism, Cinema, And The Question Of Diffused Religion In Modern China, Teng-Kuan Ng Jul 2024

Of Light And Shadows: Buddhism, Cinema, And The Question Of Diffused Religion In Modern China, Teng-Kuan Ng

Research Collection College of Integrative Studies

While the scholarship on premodern Chinese Buddhism has explored the tradition’s rich diffusion throughout various realms of sociocultural life, the study of modern Chinese Buddhism leans heavily towards its monastic, institutional, and overtly “religious” forms. This split mirrors the logic of modern secularization, whereby religion should be rationally differentiated from the broader social fabric, institutionalized, and delimited within its own discrete functional sphere. This article rethinks the putative rupture between Chinese Buddhism’s past and present incarnations. Through the prism of cinema, a technology that arrived on Chinese shores at the same moment as the Western concept of religion, I illuminate …


Double-Balloon Catheter-Mediated Transarterial Chemotherapy Delivery In A Swine Model: A Mechanism Recruiting The Vasa Vasorum For Localized Therapies, Ripal Gandhi Jul 2024

Double-Balloon Catheter-Mediated Transarterial Chemotherapy Delivery In A Swine Model: A Mechanism Recruiting The Vasa Vasorum For Localized Therapies, Ripal Gandhi

All Publications

Purpose: Treatment of hypovascular tumors, such as pancreatic adenocarcinoma, is challenging owing to inefficient drug delivery. This report examines the potential mechanism of localized drug delivery via transarterial microperfusion (TAMP) using a proprietary adjustable double-balloon occlusion catheter in a porcine model.

Materials and methods: Adult Yorkshire swine (N = 21) were used in the Institutional Animal Care & Use Committee-approved protocols. The RC-120 catheter (RenovoRx, Los Altos, California) was positioned into visceral, femoral, and pulmonary arteries with infusion of methylene blue dye, gemcitabine, or gold nanoparticles. Transmural delivery was compared under double-balloon occlusion with and without side-branch exclusion, single-balloon occlusion, …