Digital Commons Network^™

Wilson, Debbie W. Little Strength, Big God. Abilene, Tx: Leafwood Publishers, 2023., Katie M. Meeks

The Christian Librarian

No abstract provided.

Development And Validation Of The Identity Negotiation Experiences And Strategies Scale, Renee V. Galliher, Joshua G. Parmenter, Lee Pradell, Theo Klimstra

Psychology Faculty Publications

A rich theoretical and empirical literature captures experiences of identity conflict and tension at the nexus of identity domains that feel incompatible. The Identity Negotiation Experiences and Strategies (INES) scale was developed to provide a quantitative tool for capturing experiences of identity strain or conflict, and strategies for responding to or managing strain. Focus groups with college students from the United States, the Netherlands, and Finland were used to develop a pool of items capturing students' identity negotiation experiences. Subsequently, two college student samples from the United States and the Netherlands were used to refine the scale and assess psychometric …

Student Nurse Experiences Of Retention Strategies And The Perceived Contribution To Academic Progress, Jessica Dugas

Walden Dissertations and Doctoral Studies

There is a worldwide nursing shortage that has been heightened by the COVID-19 pandemic. Several factors have contributed to the worsening shortage, including high attrition rates in nursing programs. Retention strategies have been suggested to support nursing students during their education to have success and graduate. The purpose of this descriptive qualitative study was to explore how nursing students experience retention strategies and their perceived contributions to academic progress. Bandura’s social cognitive theory was the theoretical framework used to guide the study. Data were collected from one-on-one interviews with 12 nursing students recruited using purposeful and snowball sampling. Data were …

Global Burden Of Cardiovascular Disease Attributable To Smoking, 1990–2019: An Analysis Of The 2019 Global Burden Of Disease Study, Abdul Mannan Khan Minhas, Ramy Sedhom, Estelle D Jean, Michael D Shapiro, Julio A Panza, Mahboob Alam, Salim S Virani, Christie M Ballantyne, Dmitry Abramov

Faculty, Staff and Students Publications

Aims: This study aims to investigate the trends in the global cardiovascular disease (CVD) burden attributable to smoking from 1990 to 2019.

Methods and results: Global Burden of Disease Study 2019 was used to analyse the burden of CVD attributable to smoking (i.e. ischaemic heart disease, peripheral artery disease, stroke, atrial fibrillation and flutter, and aortic aneurysm). Age-standardized mortality rates (ASMRs) per 100 000 and age-standardized disability-adjusted life year rates (ASDRs) per 100 000, as well as an estimated annual percentage change (EAPC) in ASMR and ASDR, were determined by age, sex, year, socio-demographic index (SDI), regions, and countries or …

Sutureless Valves, A "Wireless" Option For Patients With Aortic Valve Disease: Jacc State-Of-The-Art Review, Cristiano Spadaccio, Antonio Nenna, Angelo Pisani, Grzegorz Laskawski, Francesco Nappi, Marc R Moon, Fausto Biancari, Arminder S Jassar, Kevin L Greason, Malakh L Shrestha, Nikolaos Bonaros, David Rose

Faculty, Staff and Students Publications

Transcatheter technologies triggered the recent revision of the guidelines that progressively widened the indications for the treatment of aortic stenosis. On the surgical realm, a technology avoiding the need for sutures to anchor the prosthesis to the aortic annulus has been developed with the aim to reduce the duration of cardiopulmonary bypass and simplify the process of valve implantation. In addition to a transcatheter aortic valve replacement (TAVR)-like stent that exerts a radial force, these so-called "rapid deployment valves" or "sutureless valves" for aortic valve replacement also have cuffs to improve sealing and reduce the risk of paravalvular leak. Despite …

Trust Criteria For Artificial Intelligence In Health: Normative And Epistemic Considerations, Kristin Kostick-Quenet, Benjamin H Lang, Jared Smith, Meghan Hurley, Jennifer Blumenthal-Barby

Center for Medical Ethics and Health Policy Staff Publications

Rapid advancements in artificial intelligence and machine learning (AI/ML) in healthcare raise pressing questions about how much users should trust AI/ML systems, particularly for high stakes clinical decision-making. Ensuring that user trust is properly calibrated to a tool's computational capacities and limitations has both practical and ethical implications, given that overtrust or undertrust can influence over-reliance or under-reliance on algorithmic tools, with significant implications for patient safety and health outcomes. It is, thus, important to better understand how variability in trust criteria across stakeholders, settings, tools and use cases may influence approaches to using AI/ML tools in real settings. As …

Bile Acid-Sensitive Human Norovirus Strains Are Susceptible To Sphingosine-1-Phosphate Receptor 2 Inhibition, Victoria Tenge, B Vijayalakshmi Ayyar, Khalil Ettayebi, Sue E Crawford, Nicole M Hayes, Yi-Ting Shen, Frederick H Neill, Robert L Atmar, Mary K Estes

Faculty, Staff and Students Publications

Human noroviruses (HuNoVs) are a diverse group of RNA viruses that cause endemic and pandemic acute viral gastroenteritis. Previously, we reported that many HuNoV strains require bile or bile acid (BA) to infect human jejunal intestinal enteroid cultures. BA was not essential for the replication of a pandemic-causing GII.4 HuNoV strain. We found the hydrophobic BA glycochenodeoxycholic acid (GCDCA) promotes the replication of the BA-dependent strain GII.3 in jejunal enteroids. Furthermore, we found that inhibition of the G-protein-coupled BA receptor, sphingosine-1-phosphate receptor 2 (S1PR2), by JTE-013, reduced GII.3 infection dose-dependently and inhibited GII.3 cellular uptake in enteroids. Herein, we sought …

Hyaluronan Mediates Cold-Induced Adipose Tissue Beiging, Xi Chen, Yifan Wang, Huiqiao Li, Yanru Deng, Charlise Giang, Anying Song, Yu'e Liu, Qiong A Wang, Yi Zhu

Faculty, Staff and Students Publications

Adipose tissue beiging refers to the process by which beige adipocytes emerge in classical white adipose tissue depots. Beige adipocytes dissipate chemical energy and secrete adipokines, such as classical brown adipocytes, to improve systemic metabolism, which is beneficial for people with obesity and metabolic diseases. Cold exposure and β3-adrenergic receptor (AR) agonist treatment are two commonly used stimuli for increasing beige adipocytes in mice; however, their underlying biological processes are different. Transcriptional analysis of inguinal white adipose tissue (iWAT) has revealed that changes in extracellular matrix (ECM) pathway genes are specific to cold exposure. Hyaluronic acid (HA), a non-sulfated linear …

Lipid-Associated Macrophages Reshape Bat Cell Identity In Obesity, Francesca Sciarretta, Wentong Jia, Jonathan R Brestoff, Et Al.

2020-Current year OA Pubs

Obesity and type 2 diabetes cause a loss in brown adipose tissue (BAT) activity, but the molecular mechanisms that drive BAT cell remodeling remain largely unexplored. Using a multilayered approach, we comprehensively mapped a reorganization in BAT cells. We uncovered a subset of macrophages as lipid-associated macrophages (LAMs), which were massively increased in genetic and dietary model of BAT expansion. LAMs participate in this scenario by capturing extracellular vesicles carrying damaged lipids and mitochondria released from metabolically stressed brown adipocytes. CD36 scavenger receptor drove LAM phenotype, and CD36-deficient LAMs were able to increase brown fat genes in adipocytes. LAMs released …

Transcriptional Analysis Of Primary Ciliary Dyskinesia Airway Cells Reveals A Dedicated Cilia Glutathione Pathway, Jeffrey R. Koenitzer, Deepesh Kumar Gupta, Wang Kyaw Twan, Huihui Xu, Nicholas Hadas, Finn J. Hawkins, Mary Lou Beermann, Gervette M. Penny, Nathan T. Wamsley, Andrew Berical, Michael B. Major, Susan K. Dutcher, Steven L. Brody, Amjad Horani

2020-Current year OA Pubs

Primary ciliary dyskinesia (PCD) is a genetic condition that results in dysmotile cilia. The repercussions of cilia dysmotility and gene variants on the multiciliated cell remain poorly understood. We used single-cell RNA-Seq, proteomics, and advanced microscopy to compare primary culture epithelial cells from patients with PCD, their heterozygous mothers, and healthy individuals, and we induced pluripotent stem cells (iPScs) generated from a patient with PCD. Transcriptomic analysis revealed unique signatures in PCD airway cells compared with their mothers' cells and the cells of healthy individuals. Gene expression in heterozygous mothers' cells diverged from both control and PCD cells, marked by …

A Comparative Analysis Of Sars-Cov-2 Variants Of Concern (Voc) Spike Proteins Interacting With Hace2 Enzyme, Jiawei Chen, Lingtao Chen, Heng Quan, Soongoo Lee, Kaniz Fatama Khan, Ying Xie, Qiaomu Li, Maria Valero, Zhiyu Dai, Yixin Xie

2020-Current year OA Pubs

In late 2019, the emergence of a novel coronavirus led to its identification as SARS-CoV-2, precipitating the onset of the COVID-19 pandemic. Many experimental and computational studies were performed on SARS-CoV-2 to understand its behavior and patterns. In this research, Molecular Dynamic (MD) simulation is utilized to compare the behaviors of SARS-CoV-2 and its Variants of Concern (VOC)-Alpha, Beta, Gamma, Delta, and Omicron-with the hACE2 protein. Protein structures from the Protein Data Bank (PDB) were aligned and trimmed for consistency using Chimera, focusing on the receptor-binding domain (RBD) responsible for ACE2 interaction. MD simulations were performed using Visual Molecular Dynamics …

A Pre-Vaccination Immune Metabolic Interplay Determines The Protective Antibody Response To A Dengue Virus Vaccine, Adam-Nicolas Pelletier, Gabriela Pacheco Sanchez, Abdullah Izmirly, Mark Watson, Tiziana Di Pucchio, Karina Inacio Carvalho, Abdelali Filali-Mouhim, Eustache Paramithiotis, Maria Do Carmo S T Timenetsky, Alexander Roberto Precioso, Jorge Kalil, Michael S Diamond, Elias K Haddad, Esper G Kallas, Rafick Pierre Sekaly

2020-Current year OA Pubs

Protective immunity to dengue virus (DENV) requires antibody response to all four serotypes. Systems vaccinology identifies a multi-OMICs pre-vaccination signature and mechanisms predictive of broad antibody responses after immunization with a tetravalent live attenuated DENV vaccine candidate (Butantan-DV/TV003). Anti-inflammatory pathways, including TGF-β signaling expressed by CD68

Breakaway Roping – Event Analysis And Resistance Training Model, Andrew A. Wolfe, Libby E. Winchell, Ruth Caddell, Jackson Maynard, Gillian Braden

Topics in Exercise Science and Kinesiology

Topics in Exercise Science and Kinesiology Volume 5: Issue 1, Article 9, 2024. Breakaway roping is a rodeo event that has received little empirical investigation, and to the best of our knowledge, no specialized resistance training recommendations have been disseminated. Furthermore, the purpose of this article was to (1) outline and analyze the biomechanical and physiological requirements of breakaway roping, and (2) articulate a theoretical specialized annual strength training and conditioning periodization plan for collegiate breakaway roping rodeo athletes. Included within the training plan are 8 distinct mesocycles containing general and event specific exercises of which are associated with the …

Simultaneous Acute Stretching With Whole Body Vibration Does Not Have An Additive Effect On Extensibility Of The Hip Adductor Muscles, Roger L. Hammer Dr., Peter V. Loubert, Naveen Sharma

Topics in Exercise Science and Kinesiology

Topics in Exercise Science and Kinesiology Volume 5: Issue 1, Article 8, 2024. Static stretching of hip adductor muscles is often included in traditional warm-up, though little research has been conducted to determine effective strategies for improving their flexibility. Combining whole body vibration (WBV) with static stretching has been proposed by some to be an effective method to improve flexibility without reducing force output. The purpose of this study was to investigate and compare the acute effects of static stretching, with and without WBV, on adductor muscle extensibility and strength. A randomized crossover design using a repeated measures ANOVA 2 …

The Art Of Sharing: Children's Rights In The Influencer Era, Stacey Steinberg

Florida Entertainment and Sports Law Review

Commentary on sharenting and the legal implications.

Mental Health In South Georgia: Another Area Of Disadvantage For An Underserved Region, But Pandemic-Related Policy Changes Suggest Pathways Forward, Shelly Yankovskyy, Anne Price

Proceedings of the annual meeting of the Southern Anthropological Society

Mental health is a contemporary issue of key concern among academics and policymakers, especially due to the exacerbation of mental health issues with the COVID-19 pandemic. Increases in mental health issues such as anxiety, depression, suicide, opioid overdose, and youth depression are the subject of research and governmental-allocated grant funding and new policies have been put in place at multiple institutional levels. We utilize a political economy framework to understand the incidence of mental health disorders and explore how new programs and policies have been implemented in Georgia to address and support mental health at various institutional levels, such as …

Changes At The Heart: Adapting Eucharist In The Time Of Pandemic, Marjorie M. Snipes

Proceedings of the annual meeting of the Southern Anthropological Society

During the initial COVID-19 pandemic period of 2020-2021, social institutions worldwide faced stress in adapting to immediate needs, among them places of worship which faced challenges from the disruption of social gatherings, religious services, tithing, and the celebration of key rituals. While many churches suspended or postponed rituals such as weddings, funerals, and baptisms, the practice of Eucharist presented a unique challenge. This ethnographic research focuses on mainline Christian churches in a semi-urban town in the state of Georgia (U.S.). It examines the ways that the experience of shutdown and social isolation affected the practice of Eucharist in Catholic, Baptist, …

Introduction, Kiley E. Molinari

Proceedings of the annual meeting of the Southern Anthropological Society

No abstract provided.

Front Matter, Journal Editors

Proceedings of the annual meeting of the Southern Anthropological Society

Includes Table of Contents and Contributor notes.

Five Secondary Teachers’ Developing Identities As Teachers Of Digital Writing, Brad Jacobson

Teaching/Writing: The Journal of Writing Teacher Education

The negotiation of teacher identity has been identified as a particular challenge for literacy teachers in the context of technological change and expanding beliefs about writing. This research project uses “identity” as an analytic tool to understand five secondary teachers’ development as teachers of digital writing. Following similar research on teacher development and identity (Lee, 2013), this study examines teacher identity in relation to discourse (how teachers talk about themselves) and practice (how they perform their identities in their work), with attention to how identification is influenced by and through social and cultural factors. Findings show that these teachers’ embrace …

Nevada Medical Residencies, 2024, Annie Vong, Caitlin J. Saladino, William E. Brown Jr.

Health

This fact sheet highlights medical residency data for the 2021, 2022, 2023, and 2024 graduating classes of the Kirk Kerkorian School of Medicine at the University of Nevada, Las Vegas (UNLV) and the University of Nevada, Reno (UNR) School of Medicine. This fact sheet presents data on residency program matches at the Kirk Kerkorian School of Medicine at UNLV and the UNR School of Medicine and reveals where Nevada medical school graduates pursue their residencies, and updates findings from a 2023 fact sheet exploring 2021, 2022, and 2023 graduating class data.

Using Home Telehealth To Reduce Hospital Readmission Rates In Heart Failure Patients In The Emergency Room, Margaret Ashby

Student Scholarly Projects

Practice Problem: In one hospital, the readmission rates and emergency room visit for patients who are diagnosed with heart failure (HF) was increasing.

PICOT: Among veterans who are hospitalized for HF (P) does the enrollment into a care coordination program for these veterans (I) compared to current practices (C), reduce the hospital readmission rates and emergency department visits (O) within 10-weeks (T)?

Evidence: The literature supports the idea that home telehealth as a home monitoring program for patients who have chronic diseases such as heart failure (HF) and has had success in patients with hypertension amongst patients. Transition strategies from …

Examining The Role Of Burnout: What Is Unique From The Experiences Of Essential Healthcare Workers And First Responders Who Worked Throughout Covid-19?, Jillian E. Garcia

ETD Collection

Throughout the COVID-19 pandemic, beginning in March 2020, many essential healthcare workers (HCWs) and first responders were exposed to extreme numbers of sick and dying patients daily (Maunder et al., 2021). In December 2020, at the peak of the pandemic, infected people were dying at alarming rates, with over 350,000 deaths in the United States alone (United States Census Bureau, 2022). About three years later, in May 2023, the federal government retracted the executive order which declared COVID-19 a public health emergency (Jared, 2023). Although COVID-19 is no longer identified as a public health emergency, SARS-CoV-2, the virus which causes …

Effect Of Beef Heifer Development Systems Utilizing Corn Residue And Late Summer Planted Cover Crops On Growth, Reproductive Performance, And Economics, Hannah F. Speer, Robert A. Cushman, Harvey Freetly, Jay Parsons, Jessica Windh, M. E. Drewnoski

Department of Agricultural Economics: Faculty Publications

The objective of this study was to evaluate growth and reproductive performance of heifers developed using 3 different winter systems in the midwestern U.S. Spring-born heifers (n = 1,156; 214 d of age; SD ± 17 d) were used in a 3-yr study to evaluate performance in winter development systems, which utilized cover crop (CC) and corn residue grazing. Heifers were assigned to 1 of 3 treatments: grazing corn residue with 0.77 kg/d dried distillers grains (CD) or 1.69 kg/d wheat midds (CW) supplementation followed by a grower ration in the drylot, or grazing late summer planted oat-brassica CC followed …

Intouch Week Of July 22, 2024, New York Medical College

InTouch

• Funding Will Bolster Medical School Success for Historically Disadvantaged Students
• NYMC and Lovelace Forge Powerful Ties in Health Research
• College Enhances MEC Roadway with Improved Parking
• NYMC and TU Presents “Ninety Minutes: The Medical Magazine of the Web”
• TCDM Welcomes Class of 2028
• Student Spotlight: SOM Student David Zuckerman Awarded AMA Physicians of Tomorrow Scholarship
• Alumni Spotlight: Disparities in Femoral Fractures in Children and Adolescents

Genetics Of Mdh In Humans, Adam Haberman, Celeste N. Peterson

Biology: Faculty Scholarship

Malate dehydrogenase (MDH) performs key roles in metabolism, but little is known about its function specifically in human health and disease. In this minireview, we describe the incomplete state of our knowledge of human MDH genetics. Humans have three MDH genes with a total of four validated isoforms. MDH1 and MDH2 are widely expressed, while MDH1B is only expressed in a small subset of tissues. Many mutations in MDH1 and MDH2 have been identified in patients, but only a few have been studied to determine what symptoms they cause. MDH1 has been associated with cancer and a neurodevelopmental disorder. MDH2 …

Combined Virtual Reality And Mechanical Balance Platform System With Induced Visual Roll, Shkenca Demiri

Theses

Balance impairments are a common and widespread concern in human health. Acquired through genetics, aging, illness, or prolonged exposure to different environments such as travel by sea or travel in outer space; balance impairments pose significant challenges to those affected. Traditionally, balance studies have been largely qualitative. However, technological advancements have allowed for new methodologies to be developed for analyzing postural sway in a quantitative manner. In this thesis, custom force plate technology, an advanced inertial motion unit (IMU) motion capture system, and a mechanical motion platform, in tandem with a gamification system, were integrated to collect and analyze quantitative …

James Codrington V. Steadfast Insurance Co

2024 Decisions

USDC for the District Court of the Virgin Islands

Motif-Vi Loop Acts As A Nucleotide Valve In The West Nile Virus Ns3 Helicase, Priti Roy, Zachary Walter, Lauren Berish, Holly Ramage, Martin Mccullagh

Department of Microbiology and Immunology Faculty Papers

The Orthoflavivirus NS3 helicase (NS3h) is crucial in virus replication, representing a potential drug target for pathogenesis. NS3h utilizes nucleotide triphosphate (ATP) for hydrolysis energy to translocate on single-stranded nucleic acids, which is an important step in the unwinding of double-stranded nucleic acids. Intermediate states along the ATP hydrolysis cycle and conformational changes between these states, represent important yet difficult-to-identify targets for potential inhibitors. Extensive molecular dynamics simulations of West Nile virus NS3h+ssRNA in the apo, ATP, ADP+Pi and ADP bound states were used to model the conformational ensembles along this cycle. Energetic and structural clustering analyses depict a clear …

The Court’S Abject Failure At Statutory Construction: Sackett V. Environmental Protection Agency, Sam Kalen

Catholic University Law Review

The essay critiques the Supreme Court’s novel approach toward statutory construction in Sackett (2023). The Sackett Court considered whether the Ninth Circuit applied the appropriate test to determine whether the Sackett’s property contained wetlands regulated under the Clean Water Act (CWA). In doing so, the Court cast aside what has been considered the operative test for assessing jurisdiction, the significant nexus test. In lieu of that test, the majority articulated a considerably constrained understanding of the CWA’s reach. This essay explores how it reached that understanding and why some of the Justices’ analysis is as problematic as the operative conclusion. …