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Development Of Feature Extraction Models To Improve Image Analysis Applications In Cancer, Yu Shi Aug 2024

Development Of Feature Extraction Models To Improve Image Analysis Applications In Cancer, Yu Shi

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Cancer poses a significant global health challenge. With an estimated 20 million new cases diagnosed worldwide in 2022 and 9.7 million fatalities attributable to the disease, the economic burden of cancer is immense. It impacts healthcare systems and imposes substantial costs for its care on patients and their families. Despite advancements in early detection, prevention, and treatment that have reduced overall cancer mortality rates, the growing prevalence of cancer, particularly among younger individuals, remains a pressing issue.

Recent advancements in medical imaging technology have progressed significantly with the help of emerging computer vision and artificial intelligence (AI) technology. Despite these …


"I Will Write Mad Stories": The Hysterical "I" In The Diaries Of George Eliot, Charlotte Forten Grimke, Virginia Woolf, And Sylvia Plath, Jaclyn Marie Swiderski Aug 2024

"I Will Write Mad Stories": The Hysterical "I" In The Diaries Of George Eliot, Charlotte Forten Grimke, Virginia Woolf, And Sylvia Plath, Jaclyn Marie Swiderski

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

This dissertation focuses on the long history of hysteria and the ways in which it has been used to denigrate and silence disabled women. Women diagnosed as hysterical, by either the medical establishment or the court of public opinion, are denied the right to generate knowledge about and for themselves – they are epistemologically disabled. The author argues that hysterical women have unique ways of looking at and understanding the world which push back against their epistemological disablement. In order to uncover some of this history of hysterical women, this dissertation uses the diaries of four “hysterical” women over the …


A Data-Driven Discovery System For Studying Extracellular Microrna Sorting And Rna-Protein Interactions, Sasan Azizian Aug 2024

A Data-Driven Discovery System For Studying Extracellular Microrna Sorting And Rna-Protein Interactions, Sasan Azizian

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Interactions between microRNAs (miRNAs) and RNA-binding proteins (RBPs) are pivotal in miRNA-mediated sorting, yet the molecular mechanisms underlying these interactions remain largely understudied. Few miRNA-binding proteins have been verified, typically requiring extensive laboratory work. This study introduces DeepMiRBP, a novel hybrid deep learning model designed to predict microRNA-binding proteins. The model integrates Bidirectional Long Short-Term Memory (Bi-LSTM) networks with attention mechanisms, transfer learning, and cosine similarity to offer a robust computational approach for inferring miRNA-protein interactions.

DeepMiRBP is implemented through two distinct architectures. The first architecture employs a Y-shaped model that uses Bi-LSTM networks and transfer learning to extract contextual …


Long Term Ultrasonic Monitoring And Machine Learning Investigation Of Micro-Crack Damaged Concrete, Yalei Tang Aug 2024

Long Term Ultrasonic Monitoring And Machine Learning Investigation Of Micro-Crack Damaged Concrete, Yalei Tang

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

The thermal modulation method is a recently developed nonlinear ultrasonic technique for evaluating material damage. This method utilizes thermal strain changes resulting from temperature variations to excite the nonlinear behavior of materials and modulate high-frequency ultrasonic waves within them. Its working principle suggests significant potential for application in large-scale concrete structures and in-situ monitoring of real structures. Despite numerous laboratory demonstrations of its effectiveness, several gaps remain before it can be applied to in-service large concrete structures.

This study investigates the potential of the thermal modulation technique for evaluating concrete structures in ambient conditions, addressing key uncertainties for practical implementation. …


Emergent Phenomena In Ferroelectric-Dielectric And Ferroelectric-Graphene Heterostructures, Tianlin Li Aug 2024

Emergent Phenomena In Ferroelectric-Dielectric And Ferroelectric-Graphene Heterostructures, Tianlin Li

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

This dissertation explores the emergent phenomena in epitaxial ferroelectric oxide-based heterostructures, including the negative capacitance (NC) effect in ferroelectric-dielectric systems, ferroelectric gate imposed mobility limit in graphene field-effect transistors, and ferroelectric domain-induced graphene-superlattices.

We carry out a phenomenological study of the NC effect in PbZr0.2Ti0.8O3/SrTiO3 capacitors. The Landau free-energy profile predicts a critical thickness ratio for the ferroelectric-dielectric phase transition, consistent with the observed abrupt change in remnant polarization. A static NC state is observed in the low thickness ratio region, which is compromised by the emergence of multidomain in the moderate ratio …


The Effects Of Anchor Scheme On The Central And Peripheral Contributions To Performance Fatigability, Perceived Responses And Sensations, And Psychological Factors Following Sustained, Isometric Forearm Flexion Tasks To Failure, Robert Walker Smith Aug 2024

The Effects Of Anchor Scheme On The Central And Peripheral Contributions To Performance Fatigability, Perceived Responses And Sensations, And Psychological Factors Following Sustained, Isometric Forearm Flexion Tasks To Failure, Robert Walker Smith

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

The Effects of Anchor Scheme on the Central and Peripheral Contributions to Performance Fatigability, Perceived Responses and Sensations, and Psychological Factors Following Sustained, Isometric Forearm Flexion Tasks to Failure Robert W. Smith, Ph.D. University of Nebraska, 2024 Advisor: Terry J. Housh This study assessed time to task failure (TTF), performance fatigability (PF), neuromuscular responses, central and peripheral measures of fatigue, and perceived responses including sensations and psychological factors that contributed to task termination during sustained, isometric forearm flexion tasks anchored to ratings of perceived exertion (RPE) and the torque corresponding to RPE. Fifteen men (age = 21.5 ± 2.3 yrs; …


Occurrence, Inputs, And Ecological Significance Of Antibiotics And Pharmaceuticals In Western Nebraska Streams, Katelyn F. Glause Aug 2024

Occurrence, Inputs, And Ecological Significance Of Antibiotics And Pharmaceuticals In Western Nebraska Streams, Katelyn F. Glause

School of Natural Resources: Dissertations, Theses, and Student Research

Few emerging environmental contaminants are as concerning as antibiotics. Human and animal health benefits greatly from the prudent use of antibiotics, yet we give little thought to environmental release of these biologically active compounds. Environmental occurrence of these and other pharmaceutical compounds must be measured in different environmental compartments such as municipal wastewater and in the vicinity of large animal feeding operations to understand potential effects. This study reports the results of a monitoring study in western Nebraska, with a large population of livestock and smaller but more concentrated population of humans, comparing the relative environmental concentrations and loading from …


Remotely Sensed Early Warning Of Algal Blooms In An Eastern Nebraska Reservoir: A Comparison Of Temporal And Spatial Indicators, Mercy Kipenda Aug 2024

Remotely Sensed Early Warning Of Algal Blooms In An Eastern Nebraska Reservoir: A Comparison Of Temporal And Spatial Indicators, Mercy Kipenda

School of Natural Resources: Dissertations, Theses, and Student Research

Cyanobacterial harmful algal blooms (CyanoHABs) detrimentally affect human, animal, and ecosystem health. Remotely sensed early warning systems for cyanoHABs in inland lakes could contribute to more proactive water quality monitoring and help mitigate negative impacts. Advances in freely available remote sensing imagery, with finer spatial, temporal, and spectral resolutions, present new opportunities for the development and comparative analysis of methods to detect sudden deterioration in lake water quality. In this thesis, I compared and tested for temporal and spatial early warning signals of cyanoHABs in field-based and remotely sensed datasets from 2019 to 2023 in Pawnee Lake in southeast Nebraska, …


Assessing, Restoring, And Centering Social–Ecological Relationships For Advancing Social–Ecological Resilience In The Northern Great Plains Grasslands, Katia Pilar Carranza Bernal Aug 2024

Assessing, Restoring, And Centering Social–Ecological Relationships For Advancing Social–Ecological Resilience In The Northern Great Plains Grasslands, Katia Pilar Carranza Bernal

School of Natural Resources: Dissertations, Theses, and Student Research

The Northern Great Plains grasslands are social-ecological systems that were shaped by evolutionary and Indigenous social-ecological relationships. European colonization disrupted many of these interactions, including the coupling of fire and grazing, and degraded social-ecological resilience, shifting these grasslands to a new state. For those reasons, my research focused on assessing, restoring, and centering evolutionary and Indigenous social-ecological relationships for advancing social-ecological resilience in the Northern Great Plains grasslands. I first performed a study in the Nebraska Sandhillls assessing the potential of patch-burn grazing to support grassland resilience by comparing its effects to those of rotational grazing. Through vegetation and bird …


Integration Of Matlab And Machine Learning To Accelerate Evaluation Of Biological Activity In Agricultural Soils And Promote Soil Health Improvement Goals, Andrew Stiven Ortiz Balsero Aug 2024

Integration Of Matlab And Machine Learning To Accelerate Evaluation Of Biological Activity In Agricultural Soils And Promote Soil Health Improvement Goals, Andrew Stiven Ortiz Balsero

Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research

Traditionally, assessments of soil biological activity have been confined to laboratory settings, creating a disconnect with practical in-field methods. To bridge this gap, cotton fabric degradation has been used to illustrate soil microbial activity under different management practices. While effective, these demonstrations are subjective and labor-intensive.

Researchers have explored using image processing software like ImageJ and Adobe Photoshop to streamline this process. Although these tools accurately quantified fabric degradation under varying soil conditions, the methods remained labor-intensive and complex. Consequently, these methods were still not ideal for on-farm use by agricultural practitioners.

To further address labor and complexity limitations, the …


The Use Of Fourier-Transformed Infrared Spectroscopy With An Infrared Biotyper To Establish Classifiers For Major Serogroups Of Moraxella Bovis Based On Spectral Profiles, Jordyn Bailey Schommer Aug 2024

The Use Of Fourier-Transformed Infrared Spectroscopy With An Infrared Biotyper To Establish Classifiers For Major Serogroups Of Moraxella Bovis Based On Spectral Profiles, Jordyn Bailey Schommer

Honors Program: Senior Projects (Public)

A classifier tool was created to identify major serogroups of Moraxella bovis based on spectral profiles collected from bacterial cells through the use of Fourier transformed infrared spectroscopy. M. bovis strains were selected from a group of previously sequenced and genotyped isolates, which provided the pilin sequence type for each isolate. The obtained spectroscopic profiles were analyzed through artificial neural networks to create a classifier tool that could identify the PilA type for unknown strains. Once a sufficient spectral library was obtained, the isolates were split into a training and a validation group, each containing spectra from isolates of five …


Child And Caregiver’ Perspective On Barriers To Asthma Management At A Tertiary Referral Hospital In Kenya, Joan Kwesigabo Ahimbisibwe Aug 2024

Child And Caregiver’ Perspective On Barriers To Asthma Management At A Tertiary Referral Hospital In Kenya, Joan Kwesigabo Ahimbisibwe

Master of Medicine in Paediatrics and Child Health

Background: Asthma is one of the most common chronic conditions in children, with significant morbidity and mortality, especially in Africa. Achieving adequate asthma control in children remains challenging due to gaps between standard recommended management strategies and treatment practices. This study explored barriers to asthma management as perceived by children and their caregivers in a private tertiary care setting in Kenya.

Methods: An exploratory phenomenological qualitative study was conducted at Aga Khan University Hospital (AKUH), Nairobi. Children aged 6–18 years with a confirmed diagnosis of asthma and their caregivers were recruited. Participants had been receiving treatment for at …


League Of Women Voters Of The Huntington Area E-Mail Bulletin, August 2024, League Of Women Voters Of The Huntington Area Aug 2024

League Of Women Voters Of The Huntington Area E-Mail Bulletin, August 2024, League Of Women Voters Of The Huntington Area

League of Women Voters of the Huntington Area Bulletin 2020 - Present

The periodical is published by the League, which is a nonpartisan political organization that encourages the informed and active participation of citizens in government and influences public policy through education and advocacy.


Theoretical Justifications For Trade Secrets Protection Of Routine Business Information, Timothy Murphy Aug 2024

Theoretical Justifications For Trade Secrets Protection Of Routine Business Information, Timothy Murphy

Buffalo Law Review

For over a century trade secret law has protected internal business information from misappropriation by departing employees. Over this time, courts developed various limiting doctrines to minimize the impact of this broad protection on employee mobility in particular cases. However, the workplace has changed significantly over this time and these changes raise substantial questions as to whether there is any valid theoretical justification for continuing to protect routine business information under trade secret law. In an environment where the vast majority of trade secrets claims are against former employees, the lack of sound justification for protecting routine business information, the …


Can You Hear Me Now? An Improvement Science Study On Policy Change In Public Schools, William G. Rhoden Jr. Aug 2024

Can You Hear Me Now? An Improvement Science Study On Policy Change In Public Schools, William G. Rhoden Jr.

All Dissertations

The purpose of this study was to discover what the perceptions of music teachers, specifically high school band directors in upstate South Carolina (S.C.), on their ability to affect meaningful policy change in SC public schools and what roadblocks exist or remain in the way of affecting policy change. Using improvement science as the methodology, this study employed the Plan, Do, Study, Act (PDSA) cycle to discover the effectiveness of this study, make recommendations for future research, and plan for future PDSA cycles. This study used interviews to collect initial data on the participants’ perceptions on their abilities to affect …


A Quality Improvement Project On The Evaluation Of A Community Gastroenterology Advanced Practice Providers’ Update On The Utilization Of The American College Of Gastroenterology (Acg) Recommendation For Annual Depression Screening In Patients With Inflammatory Bowel Disease, Yolanda Levy Dnp, Fnp-Bc Aug 2024

A Quality Improvement Project On The Evaluation Of A Community Gastroenterology Advanced Practice Providers’ Update On The Utilization Of The American College Of Gastroenterology (Acg) Recommendation For Annual Depression Screening In Patients With Inflammatory Bowel Disease, Yolanda Levy Dnp, Fnp-Bc

All Dissertations

Inflammatory bowel disease (IBD) is an autoimmune disease that can result in chronic inflammation in the gastrointestinal tract (Farbod et al., 2021). The two most common types of IBD are called Crohn’s disease and Ulcerative Colitis. There have been several studies that have shown how the psychological disorders, including depression, can be associated with flares of IBD (Farraye et al., 2017). The American College of Gastroenterology (ACG) published clinical practice guidelines in 2017, which recommended gastroenterology (GI) healthcare providers screen for depression in all patients with IBD at least once annually (Farraye et al., 2017). This quality improvement did show …


A Descriptive Study: Aging In Place In The Rural Southeastern United States, Dama G. Cooley Aug 2024

A Descriptive Study: Aging In Place In The Rural Southeastern United States, Dama G. Cooley

Electronic Theses and Dissertations

Older Americans will soon outnumber children and younger adults. In 2022, there were 58 million older adults. By 2050, older adult numbers will grow to 82 million, and by 2060, 100 million. The National Institute on Aging calls for ongoing research on the impact that a historically large aging population will have on health, well-being, and quality of life. A key concern is how to meet needs while decreasing costs associated with institutional long-term care.

Most of these elders reside in the community and wish to live in their homes throughout their lives, but they will experience an increased need …


Bearing The Woken Bear: Kazakhstani Educators Making Sense Of The Russian Invasion In Ukraine And Its Consequences For Internationalization Of Higher Education In Kazakhstan Aug 2024

Bearing The Woken Bear: Kazakhstani Educators Making Sense Of The Russian Invasion In Ukraine And Its Consequences For Internationalization Of Higher Education In Kazakhstan

Journal of Comparative & International Higher Education

Special Issue


Pre-Service Teaching And Work-Integrated Learning (Wil) In A Diverse And Democratic South African School Setting: A Social Theoretical Perspective Aug 2024

Pre-Service Teaching And Work-Integrated Learning (Wil) In A Diverse And Democratic South African School Setting: A Social Theoretical Perspective

Journal of Comparative & International Higher Education

No abstract provided.


An Exploratory Survey Of Post-Graduation Employment Location Preferences Among International Students In Missouri, Usa Aug 2024

An Exploratory Survey Of Post-Graduation Employment Location Preferences Among International Students In Missouri, Usa

Journal of Comparative & International Higher Education

No abstract provided.


Child Privacy In The Digital Era: Is Coppa Enough?, Melannie Sandoval Aug 2024

Child Privacy In The Digital Era: Is Coppa Enough?, Melannie Sandoval

Joint PIJIP/TLS Research Paper Series

Children growing up in the digital age are experiencing an entirely different world than their parents once did. While most adults’ first online experience occurred on a bulky desktop computer, today’s children are born into a society that is largely digitized and where online accessibility is at the swipe of a pocket-sized smartphone. Despite the many benefits that this generation of children enjoys due to the increased access to the internet and innovative technology, parents, child advocates, and privacy experts caution against the dangers that arise when children enter the digital landscape.

Part I of this paper delves into children’s …


Willingness To Report Sexual Victimization Through Formal And Informal Routes And The Correlation To Victim’S Race, Sexual Orientation, And Gender Identity, Tara Diltz Aug 2024

Willingness To Report Sexual Victimization Through Formal And Informal Routes And The Correlation To Victim’S Race, Sexual Orientation, And Gender Identity, Tara Diltz

Master's Theses

The purpose of this study is to understand the impact, if any, that holding marginalized identities has on the willingness to report sexual victimization to law enforcement, Title IX offices, and informal support routes. This study examines the various factors that may influence one’s willingness to report sexual victimization through both formal and informal routes. Formal routes include law enforcement and Title IX, while informal routes involve the self-disclosure of victimization to families, friends, or romantic partners. This research specifically explores how racial and ethnic identities, sexual orientation, and gender identity can influence an individual's perceived willingness to report sexual …


Higher Education On The Texas Blackland Prairie: Trinity University's Civil War Era, Sarah Beth Kaufman Aug 2024

Higher Education On The Texas Blackland Prairie: Trinity University's Civil War Era, Sarah Beth Kaufman

Sociology & Anthropology Faculty Research

The article provides a model for other southern colleges and universities founded during the Civil War era to clarify how they, too, benefited from the slave economy. It describes how Trinity University's founders were able to accomplish their institution's unlikely survival and enrich their own positions by creating a valuable new educational commodity. It also explores the historiography of nineteenth-century higher education.


Georgia Library Association Division Officer Candidates For 2025, Kim Copenhaver Aug 2024

Georgia Library Association Division Officer Candidates For 2025, Kim Copenhaver

Georgia Library Quarterly

No abstract provided.


Power Controller For Insulated Solar Electric Cooker, Ryan Koshy, Justin Tae-Hoon Kim Aug 2024

Power Controller For Insulated Solar Electric Cooker, Ryan Koshy, Justin Tae-Hoon Kim

Electrical Engineering

Insulated Solar Electric Cookers, or ISECookers, are devices created to aid those in impoverished regions improve safety, sustainability, and quality of life regarding their cooking practices. ISECookers present an alternative to traditional biofuel/biomass energy sources and provide a closed-loop, self-sustaining system that can be used in a variety of environments. These devices present solutions to widespread issues such as pollution, deforestation, and hazardous emissions as a result of traditional cooking in developing regions around the world. A notable obstacle of these devices is power delivery. Given the varying conditions experienced by a solar panel (inclement weather, irradiance irregularities, etc.), it …


Establishing A Health Equity Office: The Importance Of Recentering Equity, Aswita Tan-Mcgrory, Amita Bey, John Cowden, Hans B. Kersten, Arie Nettles, W Cody Reynolds, Valerie L. Ward, Lenny Lopez Aug 2024

Establishing A Health Equity Office: The Importance Of Recentering Equity, Aswita Tan-Mcgrory, Amita Bey, John Cowden, Hans B. Kersten, Arie Nettles, W Cody Reynolds, Valerie L. Ward, Lenny Lopez

Manuscripts, Articles, Book Chapters and Other Papers

Objectives: The Pediatric Health Equity Collaborative (PHEC) set out to describe the best practices for establishing a health equity-focused office within a clinical setting. Study Design: Survey and in-depth interviews of the members of the PHEC comprised pediatric care delivery systems in the United States and Canada. Methods: Human-centered design methods were utilized in an iterative fashion to develop and agree on survey and interview domains. The final seven domains were as follows: (1) history of the office, (2) general description of the office, (3) position of the office in the organization, (4) budget and finance, (5) stakeholders, (6) community …


Intestinal Crypt Apoptosis As An Orchestrator Of Necrotizing Enterocolitis: A New Mechanism?, Wei Yu, Aparna Venkatraman, Venkatesh Sampath Aug 2024

Intestinal Crypt Apoptosis As An Orchestrator Of Necrotizing Enterocolitis: A New Mechanism?, Wei Yu, Aparna Venkatraman, Venkatesh Sampath

Manuscripts, Articles, Book Chapters and Other Papers

No abstract provided.


Perspectives Of Academic Nurse Leaders Regarding Mentorship Of Novice Nurse Faculty, Suzanne Campbell Aug 2024

Perspectives Of Academic Nurse Leaders Regarding Mentorship Of Novice Nurse Faculty, Suzanne Campbell

Dissertations

This qualitative descriptive study sought to describe the perspectives of academic nurse leaders (ANLs) in direction of mentorship for novice nurse faculty. By examining the experiences and perspectives of these individuals, vital knowledge gained from this study will benefit future academic nurse leaders, faculty, students, and stakeholders in easing the difficult transition novice nurse faculty face as they enter academia. These perspectives had not previously been studied in depth. Fourteen participants were interviewed who served as deans, directors, or department heads of nursing education programs in Bachelor of Science in Nursing or Associate Degree in Nursing programs at U.S. public …


A Comparative Descriptive Study Exploring Undergraduate Versus Graduate Self-Regulated Learning In Online Nursing Courses, Monica Panaitisor Aug 2024

A Comparative Descriptive Study Exploring Undergraduate Versus Graduate Self-Regulated Learning In Online Nursing Courses, Monica Panaitisor

Dissertations

Preparation of new graduate nurses is more important now than ever given the current state of health care. The pandemic has caused online nursing education to be a permanent content delivery modality across all degree programs. Best practices for e-learning only address course organization, instructional materials, learner interaction, course technology, and support while having no regard for the unique learner needs of different degree levels. Online learning success could be determined by how well students are able to self-regulate their learning; however, these behaviors have rarely been measured and compared in nursing students at different degree levels taking online nursing …


Loneliness Among Black/African American Adults Living With Hiv: Sociodemographic And Psychosocial Correlates And Implications For Adherence., Nipher Malika, Laura M. Bogart, Matt G. Mutchler, Kathy Goggin, David J. Klein, Sean J. Lawrence, Glenn J. Wagner Aug 2024

Loneliness Among Black/African American Adults Living With Hiv: Sociodemographic And Psychosocial Correlates And Implications For Adherence., Nipher Malika, Laura M. Bogart, Matt G. Mutchler, Kathy Goggin, David J. Klein, Sean J. Lawrence, Glenn J. Wagner

Manuscripts, Articles, Book Chapters and Other Papers

Loneliness, an emerging public health problem, is higher among people living with HIV and is associated with negative health outcomes. Black/African Americans have a high burden of HIV, and little is known about the characteristics of loneliness among Black adults living with HIV; therefore, this study sought to understand the sociodemographic and psychosocial correlates of Black adults living with HIV who are lonely and the implications of loneliness for their health outcomes. A sample of 304 Black adults living with HIV (73.8% sexual minority men) in Los Angeles County, CA, USA, completed the survey items assessing sociodemographic and psychosocial characteristics, …