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Living Color: Aesthetic Surfaces And Political Life In Brazil, Samuel E. Novacich Sep 2024

Living Color: Aesthetic Surfaces And Political Life In Brazil, Samuel E. Novacich

Dissertations, Theses, and Capstone Projects

This dissertation is about the manipulation of appearances – of both the human body and the built environment – in Rio de Janeiro, Brazil. Focused on Afro-aesthetic makeup and tanning practices as well as urban renewal projects, this ethnographic study reveals how the making over of both the skin and the urban landscape shape social inequalities and contribute to productions of race, gender, and national belonging. While some of the aesthetic technologies examined herein may be characterized as “bottom up” – or as the self-fashioning tactics of marginalized Afro-Brazilians – others constitute “top down” infrastructural interventions led by the state …


Establishing A Murine Model Of Malaria-Associated Acute Kidney Injury And Demonstrating The Contribution Of Extrinsic Apoptosis To Tubular Necrosis, Johanna Bensalel-Lyampe Sep 2024

Establishing A Murine Model Of Malaria-Associated Acute Kidney Injury And Demonstrating The Contribution Of Extrinsic Apoptosis To Tubular Necrosis, Johanna Bensalel-Lyampe

Dissertations, Theses, and Capstone Projects

Malaria-associated acute kidney injury (MAKI) is a form of severe malaria (SM), which is usually caused by Plasmodium falciparum infection. Until recently, the impact of this particular complication of SM was severely underestimated and research in this area has been neglected. There is in fact a high prevalence (40-60%) of MAKI in SM patients and the associated risk of mortality and development of comorbidities is high. Furthermore, pediatric patients that recover often develop long-term complications such as chronic kidney disease or neurocognitive defects. The need for adjunctive therapies and early diagnostic biomarkers specific to this SM complication is critical but …


Response Styles In Multiscale Measures, Zebing Wu Sep 2024

Response Styles In Multiscale Measures, Zebing Wu

Dissertations, Theses, and Capstone Projects

Response style, one common aberrancy in non-cognitive assessments in psychological fields, is problematic in terms of inaccurate estimation of item and person parameters, which leads to serious reliability, validity, and fairness issues (Baumgartner & Steenkamp, 2001; Bolt & Johnson, 2009; Bolt & Newton, 2011). Response style refers to systematic individual preference or avoidance of certain response categories (Bolt & Johnson, 2009), especially in self-reported Likert-type scales. When response style occurs, the selection of response options is not only influenced by the trait(s) of interest but also affected by one’s tendency to choose specific options stylistically.

Despite the fact that the …


Just Transitions: Critical Exploration Of Environmental Policy And Decision-Making Through The Lens Of Lived Stories, Mariya Marinova Sep 2024

Just Transitions: Critical Exploration Of Environmental Policy And Decision-Making Through The Lens Of Lived Stories, Mariya Marinova

Dissertations, Theses, and Capstone Projects

This research explores perspectives on just transition, what transitional policies and practices are already set in motion, the conditions necessary to achieve it, and how this knowledge can inform environmental policy. Focusing on West Virginia, it employs qualitative methodology with open-ended interviews and develops life sketches of transitions to demonstrate how deeply intertwined just transition is with the lives of the people in places marked by extractive industries. Combining guiding principles from environmental and landscape justice, energy justice, feminist energy systems framework, and place attachment theory, the findings reveal that just transitions need to be transformative, focusing on understanding how …


Health Behaviors And Physical Health Among Young Adults With Varying Psychometric Schizotypy, Christopher Liong Sep 2024

Health Behaviors And Physical Health Among Young Adults With Varying Psychometric Schizotypy, Christopher Liong

Dissertations, Theses, and Capstone Projects

Schizophrenia has consistently been associated with increased rates of physical illness and early mortality. One explanation for this association might be poor health behaviors, as people with schizophrenia are more sedentary, less physically active, and more likely to engage in substance use compared to the general population. Schizotypy may be conceptualized as the phenotypic expression of increased risk for schizophrenia spectrum disorders, and dimensional models of schizotypy suggest that it varies on a continuum ranging from non-clinical (i.e. low schizotypy) to clinical (i.e. high schizotypy and dysfunction, as in schizophrenia). Though schizotypy and schizophrenia appear to share similar deficits and …


Reviving Hysteria: The Nineteenth Century At The End Of The Twentieth, Christina Quintana Sep 2024

Reviving Hysteria: The Nineteenth Century At The End Of The Twentieth, Christina Quintana

Dissertations, Theses, and Capstone Projects

This dissertation explores popular and medical representations of female madness in two time periods: the late nineteenth and late twentieth centuries. I argue that 1990s American culture produced an abundance of texts, images, and narratives that revitalized the iconography and medical discourses of late nineteenth-century hysteria. Analyzing popular texts, films, and cultural touchstones of the 1990s, I explore how Victorian ideas about women’s minds—such as the inherent feebleness of the female brain and nervous system; the fatalistic, life-altering effects of female puberty; the association between hysteria and deviant female sexuality; and the implicit racialization of hysteria and female madness more …


Black Horror Film And The Role Of Mood In Race Perception, Nicholas P. Whittaker Sep 2024

Black Horror Film And The Role Of Mood In Race Perception, Nicholas P. Whittaker

Dissertations, Theses, and Capstone Projects

Contemporary discussions of black or antiracist art are often haunted by an air of pessimism. This pessimism rests on the intuition that art cannot change the political realities of antiblackness and/or our relationships with blackness. In this dissertation, I resist this hegemonic view by arguing that black horror films generate a particular, politically-valuable aesthetic experience. Specifically, they allow us to experience blackness and black people as unintelligible. This, I argue, runs counter to everyday experience of blackness; when blackness appears unintelligible, we lose the sense of satisfied comprehension that characterizes our everyday experiences of it. I argue that these films …


Ethnoracial Inequality In Egalitarian Sweden: Swedish Exceptionalism And Racial Legacies, Beiyi Hu Sep 2024

Ethnoracial Inequality In Egalitarian Sweden: Swedish Exceptionalism And Racial Legacies, Beiyi Hu

Dissertations, Theses, and Capstone Projects

Ethnoracial Inequality in Egalitarian Sweden: Swedish Exceptionalism and Racial Legacies investigates the persistence of ethno-racial disparities in Sweden, a country often celebrated for its humanitarianism, egalitarianism, and tolerance. I explore several key questions: How do ethnic and racial minorities, as well as majority Swedes, perceive and understand race and ethno-racial inequalities in a country that does not officially recognize race? What sociohistorical legacies and institutionalized practices have contributed to contemporary ethnoracial inequalities in Sweden? And for ethnic and racial minorities, what are their day-to-day experiences of racism? Combining analysis of governmental data and in-depth interviews as well as exploratory spatial …


44ti/44sc Generator Development And Radiolabeling Optimization For Medical Applications, Christine E. Schmidt-Kennelty Sep 2024

44ti/44sc Generator Development And Radiolabeling Optimization For Medical Applications, Christine E. Schmidt-Kennelty

Dissertations, Theses, and Capstone Projects

In recent years, there has been a growing interest in scandium-44 (44Sc) for medical applications due to its favorable decay properties. With a relatively short half-life of 3.97 hours and high positron branching ratio of 94.3%, 44Sc is an ideal candidate for positron emission tomography (PET) imaging. However, producing 44Sc without an on-site cyclotron limits access, as its short half-life makes it impractical to ship to more remote locations.

To address this issue, 44Ti/44Sc generators have become a focal point of research, providing an onsite source of44Sc. Despite their potential, current …


Reviewing Inclusive Sex Education Curriculum: A Policy Analysis Of California’S Healthy Youth Act (2015), Patrick P. Buzzell Sep 2024

Reviewing Inclusive Sex Education Curriculum: A Policy Analysis Of California’S Healthy Youth Act (2015), Patrick P. Buzzell

Dissertations, Theses, and Capstone Projects

This study presents a critical policy analysis of California's Assembly Bill 329 (AB 329) regarding inclusive sex education, coupled with a series of coding phases of relevant data. AB 329, enacted in 2015, mandates comprehensive sexual health education in California schools, aiming to address the needs of diverse student populations, including sexually minoritized youth. The critical policy analysis examines the language, implementation, and potential impact of AB 329, considering its effectiveness in promoting inclusive sex education and mitigating disparities in sexual health outcomes among students. Utilizing CPA, textual and contextual elements of data related to AB 329 are scrutinized to …


Advancing Affective Computing: Emotion Recognition And Tracking Across Diverse Contexts (Varied Environments), Shao Liu Sep 2024

Advancing Affective Computing: Emotion Recognition And Tracking Across Diverse Contexts (Varied Environments), Shao Liu

Dissertations, Theses, and Capstone Projects

Affective Computing (AC) is an interdisciplinary field that recognizes, interprets, and processes human emotions. Emotions are complex, involving consciousness, physical sensations, and behavioral expressions, and are significant in various domains like mental health, human-computer interaction, and social security. Real-world applications of AC include monitoring drivers’ emotional states to improve road safety and understanding the emotions expressed by artists in visual arts. Traditional methods relying on facial expressions often fall short due to the nuanced nature of emotions, which vary across individuals, cultures, and contexts. Accurate AC systems require sophisticated, multimodal models to handle these variations and external factors like noise …


Digital Environments Of Reception And Governance: A Landscape Analysis Of Immigration-Related Webpages On U.S. State Websites, Orunima Chakraborti Sep 2024

Digital Environments Of Reception And Governance: A Landscape Analysis Of Immigration-Related Webpages On U.S. State Websites, Orunima Chakraborti

Dissertations, Theses, and Capstone Projects

American state governments occupy unique political roles when it comes to critical public-facing policy areas like education, health, transportation, and commerce, and therefore they administer many public services and benefits that affect immigrants and their communities. This study expands the existing knowledge of the ways in which U.S. state governments digitally engage with their immigrant populations, doing so through a landscape analysis that maps the information and resources provided for and about immigrant communities on 413 immigration-related webpages across all 50 U.S. state governments’ official websites. Data was collected in four categories for each webpage: its bureaucratic orientation, the government …


Race, Rebellion, And Counterinsurgency: California's Supermax Prisons, Stephen Jones Sep 2024

Race, Rebellion, And Counterinsurgency: California's Supermax Prisons, Stephen Jones

Dissertations, Theses, and Capstone Projects

This dissertation project concerns the geographies of counterinsurgency in California’s super-maximum-security prisons. I argue that these facilities – the first of which opened in the mid-1980s, and which were more repressive and isolating than any of California’s existing prisons – were explicitly developed in response to powerful organizing by people in prison. As early as 1973, corrections administrators and prison officers argued that dangerous prison gangs, organized along racial and geographical lines, were behind prisoner militancy, and advocated for expansive security measures including indefinite confinement in supermax prisons. I demonstrate, however, that officers and administrators deliberately promoted conflict, attempting to …


Critical Artificial Intelligence Literacy Course: Exploring Ai’S History, Mechanics, Influence, Pamela Jean Stemberg Sep 2024

Critical Artificial Intelligence Literacy Course: Exploring Ai’S History, Mechanics, Influence, Pamela Jean Stemberg

Dissertations, Theses, and Capstone Projects

The Critical Artificial Intelligence Literacy course is designed to equip students and educators with the tools to engage with Artificial Intelligence (AI) technologies critically. Initially conceived as a syllabus for the course Critical Approaches to Education Technology in the Digital Humanities Department of the Graduate Center, the project evolved into a comprehensive, modular program addressing the historical, technical, ethical, and societal dimensions of AI.

This course encourages a multidisciplinary approach by integrating perspectives from various fields, such as history, philosophy, ethics, technology, law, and social sciences. The design process draws from foundational courses like Digital Pedagogy and Methods, Theory, Design, …


Identifying Primary Proximal Caries Lesions In Pediatric Patients From Bitewing Radiographs Using Artificial Intelligence, Cesar D. Gonzalez, Zaid Badr, H. Cem Güngör, Shengtong Han, Manal Hamdan Sep 2024

Identifying Primary Proximal Caries Lesions In Pediatric Patients From Bitewing Radiographs Using Artificial Intelligence, Cesar D. Gonzalez, Zaid Badr, H. Cem Güngör, Shengtong Han, Manal Hamdan

School of Dentistry Faculty Research and Publications

Purpose: To develop a no-code artificial intelligence (AI) model capable of identifying primary proximal surface caries using bitewings among pediatric patients.

Methods: One hundred bitewing radiographs acquired at pediatric dental clinics were anonymized and reviewed. The inclusion criteria encompassed bitewing radiographs of adequate diagnostic quality of primary and mixed-dentition stages. The exclusion criteria included artifacts related to sensors’ quality, positioning errors, and motion. Sixty-six bitewing radiographs were selected. Images were uploaded to LandingLens™, a no-code AI platform. A calibrated consensus panel determined the presence or absence of proximal caries lesions on all surfaces (using ground truth labeling). The radiographs were …


Collagen: The Superior Material For Full-Thickness Oral Mucosa Tissue Engineering, Alexandra Gelin, Daniela S. Masson-Meyers, Fatemeh Amini, Keyvan Moharamzadeh, Lobat Tayebi Sep 2024

Collagen: The Superior Material For Full-Thickness Oral Mucosa Tissue Engineering, Alexandra Gelin, Daniela S. Masson-Meyers, Fatemeh Amini, Keyvan Moharamzadeh, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Background

Tissue engineering has significantly progressed in developing full-thickness oral mucosa constructs designed to replicate the natural oral mucosa. These constructs serve as valuable in vitro models for biocompatibility. testing and oral disease modeling and hold clinical potential for replacing damaged or lost oral soft tissue. However, one of the major challenges in tissue engineering of the oral mucosa is the identification of an appropriate scaffold with optimal porosity, interconnected porous networks, biodegradability, and biocompatibility. These characteristics facilitate cell migration, nutrient delivery, and vascularization. Various biomaterials have been investigated for constructing tissue-engineered oral mucosa models; collagen has demonstrated superior outcomes …


Reclaiming Healing Spaces: A Phenomenological Study On The Transformative Power Of Outdoor Therapy From The Lived Experiences Of Black Clinicians Working With Black Clients, Lynn Murphy Sep 2024

Reclaiming Healing Spaces: A Phenomenological Study On The Transformative Power Of Outdoor Therapy From The Lived Experiences Of Black Clinicians Working With Black Clients, Lynn Murphy

Dissertations

This phenomenological study involved assessing the experiences of Black therapists who engaged Black clients in outdoor therapeutic contexts. The study was founded on the existing literature that shows the quality of the therapeutic relationship is pivotal for client retention and the Western standards that have historically favored treatment within indoor environments. To contextualize this research, a comprehensive literature review was commenced, covering topics such as the decolonization of therapy, the historical and present-day relationship between Blacks and the outdoors in the United States, sedentary lifestyles, the psychological benefits of time spent in nature, various types of outdoor therapy, and the …


Infertility’S Impact On Couples’ Functioning, Elizabeth Sanders Sep 2024

Infertility’S Impact On Couples’ Functioning, Elizabeth Sanders

Dissertations

Historically, infertility has been a taboo topic of discussion and is often avoided in conversation because of the stigmatization of the diagnosis. According to the World Health Organization (2022), infertility affects 186 million individuals globally. However, there seems to be a gap in the research as it pertains to the psychological well-being and treatment of men and women diagnosed with this condition. While it has become less of a feared topic, it still is not discussed or researched enough, thus further exacerbating the gap in research on mental health and treatment options. The following dissertation completed a critical review of …


Patient-Specific Quality Assurance Of Dynamically-Collimated Proton Therapy Treatment Plans, Alonso Gutierrez, Eduardo Pons, Andrew Wroe Sep 2024

Patient-Specific Quality Assurance Of Dynamically-Collimated Proton Therapy Treatment Plans, Alonso Gutierrez, Eduardo Pons, Andrew Wroe

All Publications

Background: The dynamic collimation system (DCS) provides energy layer-specific collimation for pencil beam scanning (PBS) proton therapy using two pairs of orthogonal nickel trimmer blades. While excellent measurement-to-calculation agreement has been demonstrated for simple cube-shaped DCS-trimmed dose distributions, no comparison of measurement and dose calculation has been made for patient-specific treatment plans.

Purpose: To validate a patient-specific quality assurance (PSQA) process for DCS-trimmed PBS treatment plans and evaluate the agreement between measured and calculated dose distributions.

Methods: Three intracranial patient cases were considered. Standard uncollimated PBS and DCS-collimated treatment plans were generated for each patient using the Astroid treatment planning …


Embodied Energy Injustice And The Political Ecology Of Solar Power, Dustin Mulvaney Sep 2024

Embodied Energy Injustice And The Political Ecology Of Solar Power, Dustin Mulvaney

Faculty Research, Scholarly, and Creative Activity

Solar energy is poised to become a major source of electricity around the world. As deployment rises to terawatts levels, these industries will drive demand for specific materials, natural resources, labor, and lands with solar energy resources reconfiguring socio-ecological relations. Global change from the development of solar power commodity chains includes increased demand for minerals and metals, new places for metallurgy and smelting, shifting workforce flows, occupational safety challenges from extractive industries to semiconductor manufacturing fabs. These new geographies of production could result in increased emissions and effluents from specialty chemical industries, conservation and agricultural land use change, and questions …


Exercise Referral Schemes In The Uk: Mapping Provision And Aims, Ben Jane, John Downey Sep 2024

Exercise Referral Schemes In The Uk: Mapping Provision And Aims, Ben Jane, John Downey

School of Nursing and Midwifery

BackgroundExercise Referral Schemes (ERS) are designed so health professionals can refer certain patients to a supervised programme of physical activity. However, evaluations have questioned the effectiveness of these schemes/programmes. The aim of this study was to systematically review the provision of ERS in England and analyse related promotional material.MethodsContent analysis methods were used to analyse scheme websites and promotional material. A coding scheme was used to analyse the data, which included information on the programme’s aims, inclusion criteria, type of activities, accessibility and cost.ResultsThe study identified 625 sites offering ERS across 168 geographic areas. Findings highlighted a lack of clarity …


Peat Fires And Legacy Toxic Metal Release: An Integrative Biogeochemical And Ecohydrological Conceptual Framework, Colin P.R. Mccarter, Gareth D. Clay, Sophie L. Wilkinson, Gabriel Sigmund, Scott J. Davidson, Muh Taufik, Susan Page, Emma L. Shuttleworth, David Mclagan, Grant Chenier, Alexandra Clark, James M. Waddington Sep 2024

Peat Fires And Legacy Toxic Metal Release: An Integrative Biogeochemical And Ecohydrological Conceptual Framework, Colin P.R. Mccarter, Gareth D. Clay, Sophie L. Wilkinson, Gabriel Sigmund, Scott J. Davidson, Muh Taufik, Susan Page, Emma L. Shuttleworth, David Mclagan, Grant Chenier, Alexandra Clark, James M. Waddington

School of Geography, Earth and Environmental Sciences

Peatlands are potent landscape sinks of natural and industrial toxic metals and metalloids (TMMs) but the long-term sequestration of TMMs in peatlands is at increasing risk due to climate change enhanced peatland fires. The ability of peatlands to retain TMMs results from a host of interacting hydrological, biological, geomorphological, and chemical feedbacks, which underpin peatland functionality in general. Fire is a transformative force that often disrupts these interactions and feedbacks, leading to the potential release of TMMs to our air, land, and water. Given that wildfire burned area and severity are increasing there is a need for a conceptual understanding …


The 10 Commandments Of Endo-Bentall Repair, Mehrdad Ghoreishi Sep 2024

The 10 Commandments Of Endo-Bentall Repair, Mehrdad Ghoreishi

All Publications

No abstract available


The Performance Relationship Between The Eq-5d-5l Composite "Anxiety/Depression" Dimension And Anxiety And Depression Symptoms In A Large, General Population Sample, Emily Stella Scott, Erica I. Lubetkin, Mathieu F. Janssen, John N. Yfantopolous, Gouke J. Bonsel, Juanita A. Haagsma Sep 2024

The Performance Relationship Between The Eq-5d-5l Composite "Anxiety/Depression" Dimension And Anxiety And Depression Symptoms In A Large, General Population Sample, Emily Stella Scott, Erica I. Lubetkin, Mathieu F. Janssen, John N. Yfantopolous, Gouke J. Bonsel, Juanita A. Haagsma

Publications and Research

Purpose

This cross-sectional study aims to understand the relationship between responses on the Anxiety/Depression (A/D) dimension of the EQ-5D-5L and symptoms of anxiety and depression on the GAD-7 and PHQ-9 instruments. In doing so, we investigate the comparative performance of the dimension between diagnostic groups (i.e. anxiety (GAD-7); depression (PHQ-9); anxiety & depression versus none). We additionally investigate the discriminatory performance between sub-populations based on gender, age, education and self-reported chronic conditions.

Methods

19,902 general population participants completed a health survey in May/June 2020, from five European countries and the United States. Performance of A/D was calculated using the Area …


September 2024 Library & Learning Newsletter, Minnesota State University, Mankato. Library & Learning Dean’S Office Communications Team Sep 2024

September 2024 Library & Learning Newsletter, Minnesota State University, Mankato. Library & Learning Dean’S Office Communications Team

Library & Learning Newsletters

PDF version of the September 2024 (Volume 3, Issue 1) Library & Learning Newsletter.


Reduced Guanidinoacetate In Plasma Of Patients With Autosomal Dominant Fanconi Syndrome Due To Heterozygous P341l Gatm Variant And Study Of Organoids Towards Treatment, Ignacio Portales-Castillo, Rhea Singal, Jong Hee Song, Minsoo Son, Young Ah Goo, Ariella Coler-Reilly, Benjamin D Humphreys, Roberto Civitelli, Et Al. Sep 2024

Reduced Guanidinoacetate In Plasma Of Patients With Autosomal Dominant Fanconi Syndrome Due To Heterozygous P341l Gatm Variant And Study Of Organoids Towards Treatment, Ignacio Portales-Castillo, Rhea Singal, Jong Hee Song, Minsoo Son, Young Ah Goo, Ariella Coler-Reilly, Benjamin D Humphreys, Roberto Civitelli, Et Al.

2020-Current year OA Pubs

Autosomal dominant Fanconi syndrome due to a


Perioperative Risk Factors For Persistent Postsurgical Pain After Inguinal Hernia Repair: Systematic Review And Meta-Analysis, Harutyun Alaverdyan, Jooyoung Maeng, Peter K. Park, Kavya Narayana Reddy, Michael P Gaume, Lauren Yaeger, Michael M. Awad, Simon Haroutounian Sep 2024

Perioperative Risk Factors For Persistent Postsurgical Pain After Inguinal Hernia Repair: Systematic Review And Meta-Analysis, Harutyun Alaverdyan, Jooyoung Maeng, Peter K. Park, Kavya Narayana Reddy, Michael P Gaume, Lauren Yaeger, Michael M. Awad, Simon Haroutounian

2020-Current year OA Pubs

Persistent postsurgical pain (PPSP) is one of the most bothersome and disabling long-term complications after inguinal hernia repair surgery. Understanding perioperative risk factors that contribute to PPSP can help identify high-risk patients and develop risk-mitigation approaches. The objective of this study was to systematically review and meta-analyze risk factors that contribute to PPSP after inguinal hernia repair. The literature search resulted in 303 papers included in this review, 140 of which were used for meta-analyses. Our results suggest that younger age, female sex, preoperative pain, recurrent hernia, postoperative complications, and postoperative pain are associated with a higher risk of PPSP. …


Evaluation Of Knowledge-Based Planning Models For Male Pelvic Cbct-Based Online Adaptive Radiotherapy On Conventional Linear Accelerators, Riley C Tegtmeier, Edward L Clouser, Brady S Laughlin, Diego A Santos Toesca, Mattison J Flakus, Sara Bashir, Christopher J Kutyreff, Dean Hobbis, Daniel P Harrington, Jennifer L Smetanick, Nathan Y Yu, Carlos E Vargas, Sarah E James, Jean-Claude M Rwigema, Yi Rong Sep 2024

Evaluation Of Knowledge-Based Planning Models For Male Pelvic Cbct-Based Online Adaptive Radiotherapy On Conventional Linear Accelerators, Riley C Tegtmeier, Edward L Clouser, Brady S Laughlin, Diego A Santos Toesca, Mattison J Flakus, Sara Bashir, Christopher J Kutyreff, Dean Hobbis, Daniel P Harrington, Jennifer L Smetanick, Nathan Y Yu, Carlos E Vargas, Sarah E James, Jean-Claude M Rwigema, Yi Rong

2020-Current year OA Pubs

PURPOSE: To assess the practicality of employing a commercial knowledge-based planning tool (RapidPlan) to generate adapted intact prostate and prostate bed volumetric modulated arc therapy (VMAT) plans on iterative cone-beam computed tomography (iCBCT) datasets.

METHODS AND MATERIALS: Intact prostate and prostate bed RapidPlan models were trained utilizing planning data from 50 and 44 clinical cases, respectively. To ensure that refined models were capable of producing adequate clinical plans with a single optimization, models were tested with 50 clinical planning CT datasets by comparing dose-volume histogram (DVH) and plan quality metric (PQM) values between clinical and RapidPlan-generated plans. The RapidPlan tool …


Comprehensive Molecular Profiling Of Multiple Myeloma Identifies Refined Copy Number And Expression Subtypes, Sheri Skerget, Ravi Vij, Et Al. Sep 2024

Comprehensive Molecular Profiling Of Multiple Myeloma Identifies Refined Copy Number And Expression Subtypes, Sheri Skerget, Ravi Vij, Et Al.

2020-Current year OA Pubs

Multiple myeloma is a treatable, but currently incurable, hematological malignancy of plasma cells characterized by diverse and complex tumor genetics for which precision medicine approaches to treatment are lacking. The Multiple Myeloma Research Foundation's Relating Clinical Outcomes in Multiple Myeloma to Personal Assessment of Genetic Profile study ( NCT01454297 ) is a longitudinal, observational clinical study of newly diagnosed patients with multiple myeloma (n = 1,143) where tumor samples are characterized using whole-genome sequencing, whole-exome sequencing and RNA sequencing at diagnosis and progression, and clinical data are collected every 3 months. Analyses of the baseline cohort identified genes that are …


American Association Of Plastic Surgeons Consensus On Breast Implant-Associated Anaplastic Large-Cell Lymphoma, Mark W. Clemens, Terence M. Myckatyn, Arianna Di Napoli, Andrew L. Feldman, Elaine S. Jaffe, Cara L. Haymaker, Steven M. Horwitz, Kelly K. Hunt, Marshall E. Kadin, Colleen M Mccarthy, Roberto N. Miranda, H. Miles Prince, Fabio Santanelli Di Pompeo, Sari D. Holmes, Linda G. Phillips Sep 2024

American Association Of Plastic Surgeons Consensus On Breast Implant-Associated Anaplastic Large-Cell Lymphoma, Mark W. Clemens, Terence M. Myckatyn, Arianna Di Napoli, Andrew L. Feldman, Elaine S. Jaffe, Cara L. Haymaker, Steven M. Horwitz, Kelly K. Hunt, Marshall E. Kadin, Colleen M Mccarthy, Roberto N. Miranda, H. Miles Prince, Fabio Santanelli Di Pompeo, Sari D. Holmes, Linda G. Phillips

2020-Current year OA Pubs

BACKGROUND: In the absence of high-quality evidence, there is a need for guidelines and multidisciplinary consensus recommendations on breast implant-associated anaplastic large-cell lymphoma (BIA-ALCL). The purpose of this expert consensus conference was to evaluate the existing evidence regarding the diagnosis and management of BIA-ALCL caused by textured implants. This article aims to provide evidence-based recommendations regarding the management and prevention of BIA-ALCL.

METHODS: A comprehensive search was conducted in the MEDLINE, Cochrane Library, and Embase databases, and supplemented by manual searches of relevant English-language articles and "related articles" sections. Studies focusing on breast surgery and lymphoma associated with breast implants …