Digital Commons Network^™

The End Is Still To Come: How The Law’S Interaction With Digital Replicas And Derivative Digital Replicas Will Shape The Future, Spencer Kweskin

Notre Dame Journal of Law, Ethics & Public Policy

No abstract provided.

The World’S Oldest Profession Needs New Answers, Ariana Zaimi

Notre Dame Journal of Law, Ethics & Public Policy

No abstract provided.

The Case For Climate Refugee Protection, Nicole Theriot

Notre Dame Journal of Law, Ethics & Public Policy

No abstract provided.

Diabetes Potentiates The Emergence And Expansion Of Antibiotic Resistance, John C. Shook, Benjamin P. Darwitz, Kaleb J. Tyson, Amanda Z. Velez, Sophia K. Bridwell, Joshua B. Parsons, Sarah E. Rowe, Christopher Marshall, Brian P. Conlon, Lance R. Thurlow

Biological Sciences Faculty Research and Publications

Individuals with diabetes mellitus frequently develop severe skin and soft tissue infections (SSTIs) that are recalcitrant to antibiotic treatment. We examined how diabetes affects the emergence of antibiotic resistance in a Staphylococcus aureus SSTI. We determined that S. aureus evolves antibiotic resistance rapidly in diabetic mice, while resistance did not occur in nondiabetic mice over the course of infection. Diabetes-associated immune cell dysfunction plays a minor role in the emergence of resistance, while hyperglycemia plays a dominant role facilitating the expansion and takeover of resistant mutants in diabetic infections. Furthermore, vancomycin intermediate resistant isolates display a pronounced fitness defect in …

Editorial: Women In Antimicrobials, Resistance And Chemotherapy: 2023, Cindy Shuan Ju Teh, Krassimira R. Hristova, Ana R. Freitas

Biological Sciences Faculty Research and Publications

No abstract provided.

Evaluation Of The Accuracy Of The Niti K-Files And Gutta-Percha Cones In Gauging The Apical Foramen Using The Scanning Electron Microscope: An In Vitro Study, Marie-Louise Slim, Roula El Hachem, Lara Nasr, Romy Zouein, Rami Mhanna, Mia Karam, Issam Khalil

International Arab Journal of Dentistry

Objectives: The aim of this study was to compare the accuracy of apical gauging using NiTi K-files and gutta-percha cones and determine the level of agreement between the two methods using a Scanning Electron Microscope (SEM).

Methods: 75 circular and straight canals of mandibular first premolars were used. Canals were shaped using the R-Motion system (RM; FKG Dentaire, La Chaux-de-Fonds, Switzerland) and gauged using NiTi K-Files and gutta-percha cones matching the shaping instrument. Diameters measured on SEM images were used as the reference standard.

Results: There was a statistically significant difference in the prediction of apical diameter …

Continuous Monitoring Of Sterility: Bacterial Contamination And Disinfectant Performance In Dental Clinics, Nathaly Alsalloum, Tarek Aboajwa, Shuaib Alahmad, Nermin Almouhammad

International Arab Journal of Dentistry

Objectives: This study aimed to (1) evaluate contamination levels across three clinics (endodontic, extraction and surgery, and fixed prosthodontics), (2) identify the types and prevalence of bacteria, (3) estimate the effectiveness of a commercial disinfectant, and (4) determine the bacterial species most responsive to the disinfectant.

Methods: Equal surfaces (17.98 cm²) were swabbed, cultured on nutrient agar for the total aerobic microbial count before and after disinfection, and analyzed using settle plates. Bacterial identification was conducted through colony characteristics, Gram staining, and biochemical tests. Data were processed using SPSS version 26.

Results: The endodontic clinic exhibited …

Conservative Non-Surgical Endodontic Management Of A Large Cyst-Like Periapical Tunnel Lesion With 22-Month Cbct Follow-Up: A Case Report, Smriti Rohilla, Sameer Makkar, Sandeep Gupta

International Arab Journal of Dentistry

The present case report epitomises the successful non-surgical management of a large cyst-like periapical tunnel lesion of endodontic origin due to trauma using Lesion Sterilization and Tissue Repair technique. Endodontic orthograde treatment (and re-treatment) was performed in association with triple antibiotic paste as an intra-canal medication in a sixteen-year boy. Preoperative CBCT as well as at the 22 months CBCT followup were used to compare the evolution of the healing of the lesion. Accurate diagnosis in combination with non-surgical orthograde endodontic treatment can lead to can lead to complete healing of large lesions without any need of surgical intervention.

Adaptive Evolution Shapes The Transmissibility Of West Nile Virus In New York State, Sean M. Bialosuknia

Electronic Theses & Dissertations (2024 - present)

Arthropod-borne viruses (arboviruses), which are maintained in nature in complex transmission cycles involving hematophagic invertebrates and their vertebrate hosts, are the cause of a significant and expanding global health burden. Defining arbovirus-host interactions is necessary if we are to understand the adaptive and epidemiological potential of arboviruses. The results presented with West Nile virus (WNV Flaviviridae: Orthoflavivirus), are a compilation of such studies. WNV is the most prevalent arboviral pathogen in the U.S. and the most geographically distributed arbovirus in the world. Despite the evolutionary potential of these RNA viruses, WNV and other arboviruses have experienced only limited …

Socio-Economic And Infrastructural Determinants Of Response Time Disparities Across Emergency Service Agencies, Alice N. Ottah

Electronic Theses & Dissertations (2024 - present)

This study comprehensively analyzes the determinants of disparities in emergency response times for EMS, Fire, and Police agencies in San Francisco from 2021 to 2023, utilizing a multilevel modeling framework and publicly accessible data. Contrary to a primary reliance on structural neighborhood factors, this research reveals that while neighborhood disadvantage statistically significantly interacts with agency type to influence response times, its direct effect is weak and not uniformly consistent across services. Specifically, the analysis demonstrates that variance in call response times across neighborhoods is minimal (Intraclass Correlation Coefficients < 0.02), the effects of disadvantage are agency-specific (null effects for Police and Fire), and even when significant (for EMS calls only), response times are faster in more disadvantaged neighborhoods. These findings challenge the existing literature on emergency response times and highlight the need for tailored policy interventions that consider both neighborhood context and agency-specific operations to promote equitable emergency response.

Walk The Talk? Public Libraries And Organizational Responsiveness To Marginalized Communities, Soohyun Park

Electronic Theses & Dissertations (2024 - present)

Public libraries are public service organizations, playing a critical role in ensuring equitable access to education and information for the community. Despite their growing importance, there is limited empirical evidence on how local libraries respond to the needs of diverse socioeconomic populations within their communities. This study examines the collection management decisions of local public libraries to assess whether they make differentiated service decisions and what factors influence their responsiveness. Using the concept of organizational responsiveness, it explores organizational responsiveness through the lens of equitable distribution of public service benefits and considers the role of public administrators in shaping those …

Contributions Of Birthing People’S Prenatal Parasympathetic Nervous System Functioning And Postnatal Sensitivity On Infant Temperament, Amanda M. Flagg

Electronic Theses & Dissertations (2024 - present)

Grounded in developmental psychobiology, this research aimed to elucidate how birthing people’s physiological regulation during pregnancy may shape the early emergence of socioemotional development in early infancy. The present study examined how birthing people’s prenatal parasympathetic nervous system (PNS) activity, specifically baseline high-frequency heart rate variability (HF-HRV) and HF-HRV withdrawal, and postnatal sensitivity contributes to infant temperamental reactivity at six months of age. The study aimed to clarify early developmental mechanisms through which birthing people’s PNS shapes emerging infant temperament. Data were drawn from a longitudinal cohort of Black and African American birthing people, a population underrepresented in psychophysiological research, …

Teachers' Use Of Food Rewards In The Classroom Environment, Mckenna Fiore

UNF Graduate Theses and Dissertations

Food rewards are defined in terms of the value of a food to the individual at the time of ingestion. In classrooms, teachers may use food rewards to encourage academic achievement and appropriate classroom behavior (Hoffman et al., 2009). The use of unhealthy food rewards increases children’s desires for sweets and nonnutritive foods, which can pose risks for health and obesity-related outcomes, compared to healthier alternatives. Different characteristics, such as teaching style, classroom structure, teaching efficacy and teaching eating behavior, can be related to teacher’s use of different types of rewards. The goal of this study was to investigate the …

The Cultural Mechanisms Of Mental Health Stigma In Asian Americans, Vaishnavi Suren

UNF Graduate Theses and Dissertations

Asian Americans show hesitation seeking professional mental health services, as well as stigmatized attitudes towards help-seeking for mental health treatment in general. While the link between this stigma and lack of help-seeking is clear in past studies, there is a gap in the literature in looking at how various cultural mechanisms important to traditional Asian cultures interact with one another to contribute to mental health stigma. The goal of the current study was to examine intergenerational conflict, saving face, and temporal orientation to predict mental health stigma among Asian Americans. Participants (N = 208) were all second-generation Asian American …

A Pilot Study Of The Freeze Response: Physiological Markers Under Threat Versus Safety Video Conditions, Ula Mccarthy

UNF Graduate Theses and Dissertations

This pilot study examined physiological markers of the human freeze response during exposure to threat and safety-based video stimuli. The freeze response is an adaptive defense mechanism characterized by reduced heart rate and heightened sympathetic arousal (Roelofs, 2017; Hagenaars et al., 2014; Sagliano et al., 2014; Hermans et al., 2013). 20 university students were randomly assigned to view either a threatening or safety-based video clip while heart rate and electrodermal activity (EDA) were recorded using Biopac Bionomadix wireless systems. Trauma severity and PTSD symptomatology were assessed through validated self-report measures (BTQ; Schnurr et al., 1999), (PCL-5; Weathers et al., 2013). …

Assessment And Optimization Of Electric Vehicles Charging Infrastructure: Addressing Accessibility Disparities In Urban And Rural Areas, Dennis B. Bwire

UNF Graduate Theses and Dissertations

The widespread adoption of electric vehicles (EVs) is essential for advancing sustainable transportation systems; however, disparities in the spatial distribution of electric vehicle charging stations (EVCS) present significant challenges for equitable access. This thesis investigates both the inequities in EVCS accessibility and offers a data driven approach for optimizing the siting of future charging infrastructure.

The first part of the study investigates the accessibility of EVCS in rural and urban areas, focusing on how socio-demographic factors influence accessibility metrics. Using geographic information systems (GIS), network analysis, and binary logistic regression, spatial data on EVCS locations and socio-demographic attributes such as …

Leaving It All Behind: A Storied Experience, Brandi Sheree Wynne Winfrey

UNF Graduate Theses and Dissertations

Diversity, equity, and inclusion (DEI) professionals are experiencing an unprecedented time as conservative politicians and legislators work to dismantle DEI in higher education. In 2022, Florida became one of the first states to introduce and enact anti-DEI legislation. Few studies have examined or investigated the lived experiences of DEI professionals currently living in the midst of this experience. The purpose of this narrative inquiry was to capture and restory the lived experiences of DEI professionals employed at public Florida universities during the introduction and enactment of anti-DEI legislation. Five co-composers contributed their stories of experience as data to this narrative …

Long-Term Abundance Estimates Of A Northeast Florida Estuarine Dolphin Community: Evaluating The Impacts Of The 2013–2015 Cetacean Morbillivirus Unusual Mortality Event, Allison L. Wilkins

UNF Graduate Theses and Dissertations

Tamanend's bottlenose dolphins (Tursiops erebennus) in the St. Johns River (SJR), Jacksonville, FL, are subjected to substantial anthropogenic stressors (e.g., vessel traffic, dredging, fisheries interactions) and were heavily impacted by the 2013-2015 Mid-Atlantic cetacean morbillivirus unusual mortality event (UME). High prevalence of skin lesions and frequent sightings of emaciated dolphins suggest declining health and viability of the SJR dolphin community. Sighting data from Jul. 2011 to Oct. 2019 provided the rare opportunity to investigate long-term changes in dolphin abundance surrounding the UME. This study produced the first dolphin abundance estimate within the Jacksonville Estuarine System stock since 1997, …

Computational Pangenomics And Machine Learning For Genotype-Phenotype Analysis, Tejaswi Vemuri

UNF Graduate Theses and Dissertations

Phenotypes are the observable characteristics of an individual organism. Predicting quantitative phenotypes from genomic variation remains challenging when causal signals span both local motifs and distal regulatory contexts. Building on Frequented Regions (FRs)—subsequences conserved across genomes and extracted from a pangenome graph generated from a large collection of closely related species—we compare several modeling strategies across 35 Saccharomyces cerevisiae growth phenotypes: Random Forest (RF) on FR counts (called RFCounts), RF on FR sequences, 1D convolutional neural networks (CNN) on FR sequences, Long Short-Term Memory (LSTM) networks on FR sequences, a Genomewide Association Study (GWAS) baseline, and a sequence-based transformer model, …

The Limits Of Strategic Adaptation: Continuity And Change In German And Russian Strategic Culture, Andrew W. Rios

UNF Graduate Theses and Dissertations

This thesis paper adopts a comparative historical analytical approach to German and Russian strategic culture. It examines numerous historical, cultural, and ideational variables that have guided German and Russian strategic initiatives, particularly since the end of the Cold War. It illuminates the ways in which these factors have contributed to the diverging paths of strategic adaptation adopted by Germany and Russia since the 2022 invasion of Ukraine. Utilizing theoretical concepts from strategic culture theory, historical and sociological institutionalism, and critical juncture theory, this paper argues that the Russian invasion precipitated a fundamental shift in Germany's strategic orientation vis a vis …

Exploring The Connections Between Social Media Posts About Intimate Partner Violence And Their Influence On Women’S Physical And Mental Health, Joanna Lynn

UNF Graduate Theses and Dissertations

Intimate Partner Violence (IPV) can happen to anyone and is considered a common occurrence in the United States (U.S. Department of Justice, 2025). Social media platforms have allowed individuals to post about their IPV experiences, but such posts can be met with negative comments that are not beneficial to the survivor. This study explores how social media posts regarding IPV affect an individuals’ mental and physical health through a quasi-experimental design. Three out of the four groups of participants were exposed to a mock Instagram post that included the same caption and photo for a supportive, unsupportive, and neutral condition. …

Gendered Images In Online Political Advertising Videostyles: A Case Study Of 2024 Taiwan Presidential And Parliamentary Elections, Chia-Heng Chang

Electronic Theses & Dissertations (2024 - present)

Despite the increasing visibility of female politicians in Taiwan, the resurgence of the #MeToo movement ahead of the 2024 presidential and parliamentary elections underscores the enduring influence of patriarchal norms and gender stereotypes within Taiwanese society. Prior research in political communication has documented how gendered expectations shape voters’ perceptions of politicians’ appearances, behaviors, and perceived competence in addressing political issues. These expectations, in turn, inform how candidates strategically construct their public personas during electoral campaigns. This dissertation contributes to this body of scholarship by analyzing how Taiwanese political candidates perform gender through political advertising. Integrating the videostyle framework, gender schema …

Sulfur Chemistry For Protein Synthesis And Modification: From Thiolactone To Bicyclic Sulfoxide Frameworks, Yuming Wen

Electronic Theses & Dissertations (2024 - present)

This dissertation explores two intersecting themes in modern chemical biology: (1) the design of novel ligands for transition-metal catalysis, and (2) the development of thiolactone-mediated strategies for protein synthesis and modification in aqueous media. Together, these studies advance chemical methods for precise molecular transformations under mild, biocompatible conditions.

In the first chapter, a geometrically constrained bicyclic [3.3.1] sulfoxide framework was developed as a new class of bissulfoxide ligands for palladium-catalyzed C–H functionalization. The ligand was synthesized concisely from thiophenol through a three-step sequence and shown to promote allylic C–H amination and alkylation reactions with high efficiency. The catalytic system tolerated …

Teaching Documentary Filmmaking As Social Advocacy: The Case Of The Yangon Film School, Violet Valdez, Mon Mon Myat

Department of Communication Faculty Publications

This is a descriptive case study of Yangon Film School (Yangon, Myanmar) in a setting of protracted civil conflict that has persisted since 1968. It examined the school’s approach in the teaching of documentary filmmaking and analyzed key aspects of the school’s operations. Findings show that the documentary filmmaking taught in the school was informed by social advocacy. This was fostered through the students’ participation in films commissioned to the school by civil society organizations and the practice of participatory filmmaking. The school stood out in the Myanmar setting for its dual character as a training center and a production …

Effects Of Interventions For The Prevention And Management Of Maternal Anemia In The Advent Of The Covid-19 Pandemic: Systematic Review And Meta-Analysis, John Kyalo Muthuka Dr., Diana Kageni Mbari-Fondo, Francis Muchiri Wambura, Kelly Oluoch, Japheth Mativo Nzioki, Nabaweesi Rosemary Dr

Faculty Publications

No abstract provided.

Environmentally Persistent Free Radicals Lead To Selective Inhibition Of Cyp1 Monooxygenase Activities, And Increased Production Of Reactive Oxygen Species By Reaction Uncoupling, John Patrick Connick, Amari A. Stepter, George F. Cawley, Marilyn K. Eyer, Wayne L. Backes

School of Medicine Faculty Publications

This study focuses on the effect of Environmentally Persistent Free Radicals (EPFRs) on the P450 enzymes of the CYP1 family. EPFRs are a component of particulate pollutants, that are stable in the environment, but can generate free radicals, leading to oxidative stress and subsequent toxicity of the respiratory, cardiovascular, and immune systems once they enter an organism. The results show differences in the ability of EPFRs to inhibit CYP1-dependent substrate metabolism, with CYP1B1 being inhibited to the greatest extent. There also were differences in the ability of EPFRs to disrupt the POR•CYP1 complex, with CYP1B1 being the only form where …

Chronic Administration Of A Cannabis-Derived Mixture At An Antihyperalgesic Dose Does Not Significantly Enhance Hepatotoxicity Or The Development Of Metabolic Dysfunction-Associated Steatohepatitis In Male Mice, Kim B. Pedersen, Tomislav Jelesijevic, Tamara M. Morris, Sarah M. Melton, Ashley S. Henderson, John F. Glenn, Gregory J. Davenport, Martin J.J. Ronis, Peter J. Winsauer

School of Medicine Faculty Publications

Cannabis and cannabinoid mixtures have been linked to a variety of health benefits including pain mitigation, suppression of nausea produced by chemotherapeutic agents, anti-inflammatory effects, and effects on energy homeostasis, glucose, and lipid metabolism. The latter properties have led to the suggestion that these products could have therapeutic effects on the development of metabolic dysfunction-associated steatohepatitis (MASH) - a severe type of liver pathology in obese and diabetic patients. However, varying agonist and antagonistic properties of different cannabinoids on the endogenous cannabinoid system make prediction regarding hepatic effects and diet interactions difficult. The current study was designed to examine hepatic …

Multi-Modal Neo-Adjuvant Anti-Obesity Medications May Be More Effective Than Medically Supervised Weight Loss Or Glp-1 Therapy Alone In Preparing Bmi ≥ 70 Patients For Metabolic Surgery, Michael Kachmar, Florina Corpodean, Iryna Popiv, Kyle B. Lapenna, Denise M. Danos, Michael W. Cook, Brian A. Saunders, Jean J. Domercant, Vance L. Albaugh, Philip R. Schauer

School of Medicine Faculty Publications

Background/objectives: Optimizing patients with a body mass index (BMI) ≥ 70 kg/m² for metabolic surgery (MS) is challenging. However, pre-operative weight loss may be important for improving the safety of MS for these high-risk patients. Multi-modal anti-obesity medications (mmAOM) may enhance preoperative weight loss compared to non-pharmacologic medically supervised weight loss (NP-MSWL) or glucagon-like peptide-1 receptor agonist monotherapy (Mono-GLP-1) alone. Subjects/methods: This retrospective study analyzed 113 patients with BMI ≥ 70 kg/m² at a single metabolic disease treatment institute. Interventions/methods: Patients were categorized into NP-MSWL (n = 13), Mono-GLP-1 (n = 54), and mmAOM (n = 46) groups. The primary …

Tomatoes, Sea Cucumbers, And Ai. Conceptualizing A Casual Loop Diagram For Assessing Challenges And Opportunities Of The Urban Ocean, Elisa Fernández Ramos, Andrés Jaque Ovejero, Eva Hurtado Torán, Oz Sahin

Capítulos de libros

Could the combination of tomatoes, sea cucumbers, and AI be the glocal recipe for sustainable urban development systems? In this text, we review some of the implications of oceanic expansion, proposing an experiment to extract these and other conclusions that may help us realize its importance and the role of architects and urban designers in it. This research assumes that the coastline is fictitious, just like the boundary of cities that usually coincides with it. The city is part of the marine ecosystem and sprawls over it, primarily for productive purposes. Productivity models have shaped our cities since the beginning …

From Lithuania To Mobile: An Immigrant’S Memoir Comes To Light, Deborah Gurt

University Faculty and Staff Publications

No abstract provided.