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One, Two, Three Strikes You're Out Of The Old Tax Game: Reevaluating The Income Source Tax Prohibition In Light Of Shohei Ohtani's Record-Breaking Deal, Brendan J. Baird Jan 2025

One, Two, Three Strikes You're Out Of The Old Tax Game: Reevaluating The Income Source Tax Prohibition In Light Of Shohei Ohtani's Record-Breaking Deal, Brendan J. Baird

Case Western Reserve Law Review

No abstract provided.


Toward Measurable Explainable Ethical Ai: An Llm-Driven Data Analytics Study, Greg Bacon Jan 2025

Toward Measurable Explainable Ethical Ai: An Llm-Driven Data Analytics Study, Greg Bacon

Dissertations

Large Language Models (LLMs) have been a hot area for popular and research audiences. Users marvel subjectively at Artificial Intelligence (AI) outputs — so much that OpenAI delayed public release of Generative Pre-trained Transformer 2 (GPT-2) back in 2019, citing ``safety and security concerns.'' This research advances ethical and transparent AI through qualitative and quantitative measures between user intent and LLM responses in a way that aims to assist users with clear indications of good and poor alignment and of where to backtrack to minimize bias and hallucinations. The use case is recommending grant topics in a United States Department …


Novel Ai/Ml-Based Frameworks For Protein Conformation Selection In Drug Discovery Applications, Shivangi Gupta Jan 2025

Novel Ai/Ml-Based Frameworks For Protein Conformation Selection In Drug Discovery Applications, Shivangi Gupta

Dissertations

Drug development is a lengthy, expensive process with a high failure rate. The urgency brought on by the COVID-19 pandemic has accelerated the integration of artificial intelligence (AI) and machine learning (ML) to enhance drug discovery by increasing target specificity, reducing toxicity, and optimizing formulation strategies. Building on this momentum, this dissertation introduces novel AI/ML-driven frameworks for protein conformation selection and classification, addressing critical challenges in modern drug discovery. However, designing such a novel AI/ML data-driven framework is a difficult task because most real-world biomedical datasets suffer from class imbalance issues, which can significantly skew AI/ML model training, resulting in …


Manganism And The Development Of A Green Sustainable Low-Threshold Spectrophotometric Test For The Monitoring Of Manganese In Consumable Water, Anna Merritt Holmes Jan 2025

Manganism And The Development Of A Green Sustainable Low-Threshold Spectrophotometric Test For The Monitoring Of Manganese In Consumable Water, Anna Merritt Holmes

Dissertations

Manganism, a neurotoxic disease from the hyperaccumulation of manganese, follows an etiology that parallels Parkinsonism. Non-occupational Manganism is acquired by the lifelong accumulation of manganese through water contaminated by natural and industrial sources. Biologically active manganese (II) eludes flocculation and filtration removal methods at water utilities. The U.S. Standard Methods For the Examination of Water and Wastewater persulfate testing method uses mercury sulfate, concentrated nitric and phosphoric acids, silver nitrate, and ammonium persulfate. The low detection limit of 210 µg/L is an order of magnitude greater than the World Health Organization (WHO) allowable limit of 10-50 µg/L. In 2004, the …


Professional Development Workshop: Strategy To Increase Registered Nurse (Rn) Retention, Diane Hegedus Msn, Rn, Phrn, Cen, Npd-Bc Jan 2025

Professional Development Workshop: Strategy To Increase Registered Nurse (Rn) Retention, Diane Hegedus Msn, Rn, Phrn, Cen, Npd-Bc

Department of Education

(c) Lehigh Valley Health Network

All items are copyright to Lehigh Valley Health Network.


Implementation Of A Nurse Preceptor Online Toolkit, Kortney Welles Msn, Rn, Cmsrn Jan 2025

Implementation Of A Nurse Preceptor Online Toolkit, Kortney Welles Msn, Rn, Cmsrn

Department of Education

No abstract provided.


Empowering Caregivers Through Occupational Therapy: A Comprehensive Approach To Adolescent Mental Health Education, Shannon Grace Ring Jan 2025

Empowering Caregivers Through Occupational Therapy: A Comprehensive Approach To Adolescent Mental Health Education, Shannon Grace Ring

Occupational Therapy Capstones

Purpose: This scholarly project aimed to create an evidence-based toolkit for caregivers of adolescents currently completing partial hospitalization programming (PHP). Adolescents enrolled in PHP have experienced severe disruption in their daily functions. Adolescent mental illness is a public health concern due to its prevalence, early onset, and the impact it can have on individuals, families, and communities (Ghandour et al., 2019). Mental health disorders during adolescence can affect development by interfering with the ability to function in daily settings and achieve social, emotional, cognitive, and academic milestones (Ghandour et al., 2019). Many adolescents are also exposed to risk factors, including …


Ready Or Not, The Deadline Is Coming! Getting Onboard With Accessible Course Content, Karen Edwards, Lena Pinkston Jan 2025

Ready Or Not, The Deadline Is Coming! Getting Onboard With Accessible Course Content, Karen Edwards, Lena Pinkston

Faculty Publications

People with disabilities often have less engagement with and access to online resources (Lissitsa & Madar, 2018). Accordingly, the Department of Justice’s (DOJ) Final Rule (89 FR 31320, 2024) for Title II of the Americans with Disabilities Act of 1990 (ADA) requires many public educational institutions and others to comply with the Web Content Accessibility (WCAG) Guidelines Version 2.1 AA by April 24, 2026. Compliance officers and technology specialists across the country have been working to make sure institutional websites and apps meet the Guidelines. Despite spirited debate during the rulemaking process, the updated rule also requires instructional content within …


Trust In Ephemeral Content In Social Media Platforms: A Mixed-Method Approach Examining Online Users’ Privacy Concerns In The Case Of Snapchat, Ream Al-Ghamdi Jan 2025

Trust In Ephemeral Content In Social Media Platforms: A Mixed-Method Approach Examining Online Users’ Privacy Concerns In The Case Of Snapchat, Ream Al-Ghamdi

Graduate Thesis and Dissertation post-2024

This study investigated privacy management practices on ephemeral social media platforms, with a particular focus on Snapchat, Yik Yak, and Instagram Reels. It utilized a mixed-method approach, integrating an analysis of privacy policy terms with empirical data obtained through a quantitative survey of 346 US university students, including Saudi students studying in the United States and their American counterparts, as well as qualitative insights from in-depth interviews. Privacy policies were systematically evaluated across critical dimensions, including first-party data collection, third-party data sharing, user privacy controls, data retention practices, and compliance with international regulations such as GDPR, CCPA, and Saudi Arabia's …


Globe Resources For 2025 Summer Reading Programming, Haley F. Wicklein, Globe U.S. Coordination Office Jan 2025

Globe Resources For 2025 Summer Reading Programming, Haley F. Wicklein, Globe U.S. Coordination Office

Teacher Resources

No abstract provided.


Globe And Natural Inquirer Crosswalk Ms/Hs: Studying Air Quality And Aerosols, Alicia Carlson, Globe U.S. Coordination Office Jan 2025

Globe And Natural Inquirer Crosswalk Ms/Hs: Studying Air Quality And Aerosols, Alicia Carlson, Globe U.S. Coordination Office

Teacher Resources

No abstract provided.


Lecture Responsive Democracy And The Administrative State, Edward L. Rubin Jan 2025

Lecture Responsive Democracy And The Administrative State, Edward L. Rubin

Case Western Reserve Law Review

No abstract provided.


Booing Bohnak: How The Second Circuit Dropped The Article Iii Ball In Analyzing Standing In Class Actions Arising From Cyberattacks, Douglas H Meal Jan 2025

Booing Bohnak: How The Second Circuit Dropped The Article Iii Ball In Analyzing Standing In Class Actions Arising From Cyberattacks, Douglas H Meal

Journal of Law, Technology, & the Internet

This article examines the Second Circuit's decision in Bohnak v. Marsh & McLennan Cos., which represents a pivotal development in the interpretation of Article III standing in the context of cyberattack class actions. The court's principal ruling, which held that mere unauthorized access to personal information by reason of a cyberattack constitutes a concrete injury sufficient for standing, marks a significant departure from prior jurisprudence and misinterprets the Supreme Court's seminal Article III decision in TransUnion LLC v. Ramirez. So does the court's alternative holding that standing can be predicated on a plaintiff's risk of suffering identity theft …


Inventions Without Inventors: The Need To Recognize Ai Systems As Inventors, Niloufer Selvadurai Jan 2025

Inventions Without Inventors: The Need To Recognize Ai Systems As Inventors, Niloufer Selvadurai

Journal of Law, Technology, & the Internet

As AI systems increasingly generate innovative products and processes, a critical issue to address is the nature and extent of the patent protection that is conferred upon such outputs. The overarching objective of patent law is the support of innovation and progress. In determining applications, the clear focus of patent judgments is whether the claimed invention satisfies the required standards of inventiveness, novelty, and non-obviousness. It is hence curious that incidental references to “individuals” and “persons,” variously scattered through patent statutes, operate to deny recognition of AI inventors. This is the result of the global test litigation instigated by Dr. …


Enhancing Health And Wellness In Female University Students: A Study On The Impact Of Self-Monitoring, Goal Setting, And Feedback, Halle Landies Jan 2025

Enhancing Health And Wellness In Female University Students: A Study On The Impact Of Self-Monitoring, Goal Setting, And Feedback, Halle Landies

Masters Essays

Incorporating exercise into daily routines helps female university students navigate the challenges of university life, promotes long-term health, and fosters a balanced and productive lifestyle (Kohl, 2013). This study aims to expand the research on applied behavior analysis by examining the effectiveness of self-monitoring, goal setting, and feedback in helping female students achieve daily goals related to step count, exercise, distance walked, etc.. Using a changing criterion design, participants recorded data via an Apple Watch, with the intervention's effectiveness evaluated weekly over a six-week period.


An Active Playful Learning Guidebook For New Hampshire Early Childhood Educators, Unh Early Childhood Education Coaching Initiative, Jennifer Berube, Sarah Bond, Karen Dubois-Garofalo, Kimberly Nesbitt Jan 2025

An Active Playful Learning Guidebook For New Hampshire Early Childhood Educators, Unh Early Childhood Education Coaching Initiative, Jennifer Berube, Sarah Bond, Karen Dubois-Garofalo, Kimberly Nesbitt

Play-Based Learning Coaching and Teaching

No abstract provided.


A Governance-Centric Framework For Strengthening Healthcare Cybersecurity: A Systems Perspective, Sujatha Alla, Sai Gireesh Komaragiri, Teresa Duvall, Satluk Karahan, Nagesh Bheesetty, Vijay Kumar Chattu Jan 2025

A Governance-Centric Framework For Strengthening Healthcare Cybersecurity: A Systems Perspective, Sujatha Alla, Sai Gireesh Komaragiri, Teresa Duvall, Satluk Karahan, Nagesh Bheesetty, Vijay Kumar Chattu

Engineering Management & Systems Engineering Faculty Publications

Healthcare systems face unprecedented security and privacy challenges due to increasing digitization and interconnectedness. This paper provides a comprehensive analysis of these challenges by examining various cyberattacks, defensive mechanisms, and governance frameworks within modern healthcare infrastructure. The research systematically categorizes prevalent security threats, such as ransomware, insider threats, and data breaches, identifying vulnerabilities specific to healthcare systems. Furthermore, the study evaluates current defensive strategies, including encryption techniques, access control systems, and intrusion detection tools, assessing their effectiveness against complex cyber threats. A key focus is placed on governance structures and their role in cybersecurity resilience. The research explores how regulatory …


A Unionid Mussel Biodiversity Hotspot Experiencing Unexplained Declines: Evaluating The Influence Of Chemical Stressors Using Caged Juveniles, W. Aaron Wilson, Christine Bergeron, Jennifer Archambault, Jason M. Unrine, Jess Jones, Braven Beaty, Damian Shea, Peter R. Lazaro, Jody L. Callihan, Jennifer J. Rogers Jan 2025

A Unionid Mussel Biodiversity Hotspot Experiencing Unexplained Declines: Evaluating The Influence Of Chemical Stressors Using Caged Juveniles, W. Aaron Wilson, Christine Bergeron, Jennifer Archambault, Jason M. Unrine, Jess Jones, Braven Beaty, Damian Shea, Peter R. Lazaro, Jody L. Callihan, Jennifer J. Rogers

Plant and Soil Sciences Faculty Publications

Unionid mussel populations in a section of the Clinch River in Virginia, USA, has declined substantially, but the causes of the decline remain unknown. To investigate this zone of decline (ZOD), we deployed juvenile freshwater mussels (Villosa iris in 2012 and Lampsilis fasciola in 2013) in both cages and silos at sites within the Clinch River System. We analyzed mussel tissues for trace element and organic contaminant concentrations, shells for trace elements, and environmental media (total water, dissolved water, particulate sediment, and bedload sediment) for both inorganic and organic contaminants. We found a few differences between mussels deployed in cages …


Mitigating And Preparing For Disasters At The Organizational Level: A Global Systematic Literature Review, Abdul-Akeem Sadiq, Ratna B. Dougherty, Rebecca Entress, Bikash Adhikari, Katherine Wilson Mccoy, Emilie Rott, Grace L. Chikoto-Schultz, Shannon Maharajh Jan 2025

Mitigating And Preparing For Disasters At The Organizational Level: A Global Systematic Literature Review, Abdul-Akeem Sadiq, Ratna B. Dougherty, Rebecca Entress, Bikash Adhikari, Katherine Wilson Mccoy, Emilie Rott, Grace L. Chikoto-Schultz, Shannon Maharajh

Faculty Scholarship and Creative Works

Organizations play significant roles in society by providing goods and services and contributing to the economies of communities, globally. Amid the predicted increase in the frequency and impact of disasters, which will invariably lead to higher disaster costs, there is an urgent need to ameliorate disaster impact on society and organizations. Disaster mitigation and preparedness are strategies for stemming disaster impact and losses within organizations. Cognizant of the importance of disaster mitigation and preparedness, researchers have conducted a myriad of studies on both concepts at the organizational level. To advance knowledge on this topic, this study conducted a comprehensive systematic …


Development And Application Of Gpu Based Monte Carlo Simulation Techniques In Radiation Medicine, Satzhan Sitmukhambetov Jan 2025

Development And Application Of Gpu Based Monte Carlo Simulation Techniques In Radiation Medicine, Satzhan Sitmukhambetov

Physics Dissertations - Archive

Cancer remains a significant public health challenge, with treatments like radiation therapy forming a cornerstone of modern care. To address this challenge, advanced computer simulations can improve radiotherapy in two primary ways. From one hand, mechanistic simulations help elucidate the fundamental radiobiological working principles, which could contribute to the clinical advancements from a bottom-up framework. On the other hand, modality simulations could help design better clinical systems with better detection and therapeutic capabilities. This research enhances these critical simulation tools by introducing two significant developments.

First, this work introduces a metaphase DNA model into a microscopic Monte Carlo simulation framework …


Breaking Ground On Self-Efficacy: A Qualitative Exploration Of Intimate Partner Violence Survivors’ Experiences With Therapeutic Horticulture, Rachel Marie Reeves Jan 2025

Breaking Ground On Self-Efficacy: A Qualitative Exploration Of Intimate Partner Violence Survivors’ Experiences With Therapeutic Horticulture, Rachel Marie Reeves

Theses and Dissertations--Sociology

This dissertation explores how participation in a Therapeutic Horticulture program may support the self-efficacy of survivors of Intimate Partner Violence. Through a thematic analysis of interviews with 45 women living at a domestic violence shelter in Lexington, Kentucky, this study investigates whether and how gardening activities contributed to participants’ belief in their abilities to shape outcomes in their lives.

Findings are organized around Bandura’s four sources of self-efficacy: enactive mastery experiences, vicarious experience, verbal persuasion, and physiological/affective states. These insights contribute to feminist criminology and trauma-informed care literature by illuminating the transformative potential of nature-assisted healing programs.


Emplacing Deaths Of Despair Within The Rural Mortality Penalty: The Spatial Inequality Of Violent Death Across Rural America, Cameron A. Mcalister Jan 2025

Emplacing Deaths Of Despair Within The Rural Mortality Penalty: The Spatial Inequality Of Violent Death Across Rural America, Cameron A. Mcalister

Theses and Dissertations--Sociology

American life expectancy continues to diverge from most developed nations. Literature spanning several fields of scholarship has documented an uneven distribution of life expectancy between social groups and across geographic contexts. Frameworks such as “Deaths of Despair” and the rural mortality penalty describe the declining health trends among working class whites and rural America. But, conceptual development around these frameworks is still limited. This dissertation utilizes a rural sociological approach to bridging the gap between the Deaths of Despair framework and the rural mortality penalty by examining violent death patterns across diverse rural contexts. In doing so, I incorporate several …


News Mediated Reporting And Governmental Narratives About The Enforcement Of Elite Criminality: Exploring The Social Construction Of Financial Frauds And Discrepancies In Punishment, Dominic J. Zicari Jan 2025

News Mediated Reporting And Governmental Narratives About The Enforcement Of Elite Criminality: Exploring The Social Construction Of Financial Frauds And Discrepancies In Punishment, Dominic J. Zicari

Theses and Dissertations

This study examines how financial crime enforcement decisions are socially constructed through a qualitative content analysis of news articles and government communications pertaining to two specific cases: the Enron scandal of 2001 and the subprime mortgage crisis of 2008. The study was guided by a theoretical framework that utilizes Barak’s (2017) theory of state-routinized crime control. The rigorous analysis of 394 news articles and government communication documents revealed that the media and the state rarely framed the subprime mortgage crisis as a criminal issue. Although the Enron scandal was frequently described as financial crime, journalists and government communicators were often …


Sex-Specific Regulation Of Mash And Hepatocellular Carcinoma: A Role Of Sphk2 In Females, Bria Pierre Jan 2025

Sex-Specific Regulation Of Mash And Hepatocellular Carcinoma: A Role Of Sphk2 In Females, Bria Pierre

Theses and Dissertations

Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD) is characterized by excessive fat accumulation in the liver, with metabolic dysfunction-associated steatohepatitis (MASH) representing a more severe form that can progress to cirrhosis or hepatocellular carcinoma (HCC). The sphingosine kinases and the S1P signaling pathway are key regulators of MASH and HCC progression. While much is known about the mechanisms contributing to MASH-HCC in males, less is known for females. Nevertheless, we previously identified sphingosine Kinase 2 (SphK2) to protect females from MASH-driven HCC. This study first performed differential gene expression analysis on human liver cohorts to examine sex-specific differences in gene expression …


The Diseased Extracellular Matrix In Chronic Obstructive Pulmonary Disease Modeling, Leigh-Ann M. Antczak Jan 2025

The Diseased Extracellular Matrix In Chronic Obstructive Pulmonary Disease Modeling, Leigh-Ann M. Antczak

Theses and Dissertations

Chronic obstructive pulmonary disease (COPD) is currently the fourth leading cause of death in the world, with an increasing prevalence as the world’s population ages. In the distal regions of the lungs, COPD is characterized by progressive emphysema due to an imbalance of proteases that continuously degrade essential extracellular matrix (ECM) proteins within the alveolar walls, causing fatal tissue impairment. This dissertation examines the unique properties of this diseased lung ECM in two parts: (1) As a key constituent in inflammatory signaling that leads to increased inflammation and progression of COPD, and (2) as a tool in three-dimensional (3D) in …


Intercellular Stress Generation During 1d Collective Migration Of Cancer Cells, Logan Waddle, Jian Zhang Jan 2025

Intercellular Stress Generation During 1d Collective Migration Of Cancer Cells, Logan Waddle, Jian Zhang

2025 Research Poster Competition

Physical forces drive many cellular processes such as migration and proliferation. A metastatic tumor will have invasive strands/chains that extend from the main tumor. These chains of cells collectively migrate away from the main tumor to establish new colonies elsewhere in the body. However, how physical forces drive this collective invasion and the required energy for this process is not well understood. Invasion of a metastatic tumor to surrounding tissues leads to a majority of cancer-associated death and is often a collective effort among cells, it is therefore important to fully understand the process behind collective cancer invasion.

The goal …


Llm-Driven Fmea For Safe Human-Robot Collaboration In Disassembly, Morteza Jalali Alenjareghi, Samira Keivanpour, Yuvin Adnarain Chinniah, Sabrina Jocelyn Jan 2025

Llm-Driven Fmea For Safe Human-Robot Collaboration In Disassembly, Morteza Jalali Alenjareghi, Samira Keivanpour, Yuvin Adnarain Chinniah, Sabrina Jocelyn

Articles dans des actes de congrès

Disassembly operations often present unstructured and unpredictable scenarios, such as handling hazardous materials, addressing ergonomic strain, and managing dynamic robot interactions that pose safety risks. To tackle these challenges, we propose an innovative use of large language models (LLMs) to enhance failure mode and effect analysis (FMEA) in the context of human-robot collaboration (HRC) for disassembly tasks. We developed an LLM system leveraging retrieval-augmented generation (RAG) for real-time risk analysis and recommendation generation. RAG retrieves domain-specific information from the FMEA knowledge database, enabling accurate risk analysis, contextual understanding, and relevant recommendations based on user input and operational data. Evaluation of …


Effect Of Ventilation And Wearing A Facemask In Reducing Indoor Aerosol Transmission, Clothilde Brochot, Ali Bahloul Jan 2025

Effect Of Ventilation And Wearing A Facemask In Reducing Indoor Aerosol Transmission, Clothilde Brochot, Ali Bahloul

Articles dans des actes de congrès

The COVID-19 pandemic has significantly disrupted research in respiratory protection and transmission routes. Indeed, the pandemic has highlighted a number of issues, including those related to the performance and use of respiratory protective equipment such as masks and ventilation. A plethora of commercial and homemade masks have widely appeared during the pandemic, although they are not yet fully regulated in performance and fit test. However, with regard to the source reduction process, testing facemasks not at the inhalation, but at the source (exhalation) offers a new perspective on how to prevent particle emissions. Different means of transmission reduction are measured …


Ba Political Science Civic & Nonprofit Leadership Option, Political Science Jan 2025

Ba Political Science Civic & Nonprofit Leadership Option, Political Science

Program Revisions/Additions

No abstract provided.


Public Health / Health Administration Course Completion Attempts, Public Health Jan 2025

Public Health / Health Administration Course Completion Attempts, Public Health

Program Revisions/Additions

No abstract provided.