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Evidence That Ultraviolet B Radiation Generates Systemic Responses Via Microvesicle Particle, Niharika Annapureddy

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Ultraviolet B (UVB) radiation, ranging from 280–315 nm, has been identified as carcinogenic since 1928 and is known to cause skin cancer. Additionally, UVB exposure triggers inflammatory responses, systemic effects, and organ damage. Recent research has discovered that these adverse outcomes are facilitated by the release of microvesicle particles (MVP) via the inflammatory lipid mediator, Platelet-activating Factor (PAF). We have previously demonstrated that sunburn causes skin keratinocytes to release high levels of MVP by activating the PAF receptor (PAFR). These studies were designed to test if these microvesicles enter the bloodstream and travel to various organs, especially the gut, increasing …

Disengaged And Drowsy: Using An Adaptive System To Detect Suboptimal Learning, William Andrew Stalker

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Instruction is increasingly asynchronous, providing new opportunities but at the cost of losing some guard rails of in-person classes. One such guard rail is an instructor’s ability to detect boredom and learner disengagement. This dissertation explores the development and evaluation of an adaptive training simulator designed to respond to user engagement levels in real-time. The simulator monitors eyeblinks, comparing metrics to individual baselines to detect signs of fatigue and boredom. Participants are exposed to novel information in an audiobook recording of a textbook chapter and later quizzed to assess retention. An adaptive intervention offering periodic brief respite was tested against …

Religiosity And The Gender Violence Crisis: How Religious Affiliation Of Society Impacts Violence Against Women, Sydney Hoffman

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This thesis analyzes the impact that the religious affiliation of a population has on both the prevalence of violence against women, as well as the presence of legislation and other legal frameworks aimed at preventing violence and protecting women. Utilizing data from international organizations and nonpartisan fact tanks, regression analyses are performed with four different models and dependent variables to understand the effect religiosity has on both prevalence and prevention of gender violence. While the results of these models do not indicate a likelihood of real relationships between religiosity and the different outcomes, the thesis overall contributes further to the …

Synthetic Nucleoside Labels For Studying Cell-Free Dna, Dibya Guragai

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Cell-free DNA (cfDNA) can arise from dying cells or be actively secreted by living cells, and is found either unbound, within extracellular vesicles, or in other macromolecular complexes. cfDNA plays roles in intercellular communication and immune responses and is clinically used for diagnostics through PCR and DNA sequencing. Interestingly, our lab has detected lesions in cfDNA after treatment with DNA-damaging agents including UVB and cisplatin. These findings prompted further investigation into which DNA lesions and labels can be found in the cell-free space. Importantly, we sought a mechanism of labeling DNA with a synthetic nucleoside to enable robust tracing using …

Systemic Effects Of Varying Degrees Of Thermal Burn Injuries In Young Mice: Role Of Microvesicle Particles And Platelet-Activating Factor, Prince Wilfred

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Thermal burn injuries (TBI) result in local and systemic effects, particularly when a large body surface area is exposed to TBI. This study investigates the systemic effects of varying degrees of TBI in the murine model, focusing on the role of microvesicle particles (MVP) and Platelet-activating Factor (PAF) in mediating bacterial translocation and systemic inflammation. Utilizing the murine model, we analyzed MVP levels in the skin and blood, bacterial translocation in the gut, and the expression of pro-inflammatory mediators in the major organs at the 2-hour post-burn time point. Our studies revealed that after the two hours’ time point TBI …

Diverse Environments: Refining The Concept Of Remote Work Through A Job Demands-Resources Lens, Riley Schwanz

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Global events such as globalization, technological advancements, and fundamentally new methods for completing work are contributing factors to the mass migration of employees from in-person to more remote work modalities. Researchers have found evidence for advantages (e.g., autonomy) and disadvantages (i.e., lack of teamwork) for employees in more remote modalities. However, there are critical gaps in the literature including a lack of clear definitions, assessments, taxonomies, and application of well-established theories. Beyond focusing on the physical aspects of remote work, I proposed a new concept, degree of remoteness, to capture the psychological experience of working remotely. Further, I proposed that …

Ready, Set, Resistance: A Dual Continuum Approach To Organizational Change Acceptance, Alexandria Bohn

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With organizations operating in increasingly dynamic and competitive landscapes, organizations need to be able to get their employees to adapt to system-wide changes that are needed. However, research has suggested a 70% failure rate for organizational change initiatives (Hughes, 2011). Prior research has produced mixed research results when examining resistance and readiness to organizational change on either a single dimension (e.g., Kaplan, 1972) or two dimensions (e.g., Repovs, Drnovsek, & Kase, 2019). I extended prior research by examining resistance versus readiness as residing on a single continuum and whether effects on outcomes were moderated by change orientations. Research has suggested …

Effects Of Canagliflozin And Pioglitazone On Cardiac Ras And Sirt1 In Db/Db Diabetic Mice, Purab Sanjay Sood

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Type 2 diabetes significantly increases the risk of diabetic cardiomyopathy (DCM) and nephropathy, largely due to hyperglycemia-induced activation of the renin-angiotensin system (RAS) and elevated levels of angiotensin II (Ang II). Angiotensin converting enzyme 2 (ACE2) and neprilysin (NEP) mitigate the deleterious effects of Ang II by generating Ang-(1-7), a cardioprotective vasodilator. ACE2 is essential for cardiac function, while its deficiency exacerbates dysfunction. Furthermore, the silent information regulator 1 (SIRTl) promotes ACE2 expression and contributes to cardiovascular protection. Despite the availability of several classes of antidiabetic medications, some cardiovascular complications of diabetes persist, and intensive glycemic control does not always …

Using The Historical Equity Action Lens (Heal) To Identify And Remedy Transportation Inequities From The Akron Innerbelt Project, Olivia Lane

Williams Honors College, Honors Research Projects

This project will utilize the Historical Equity and Action Lens (HEAL) to address transportation inequities in marginalized communities by incorporating historical and cultural insights into data collection and analysis. Specifically, the project will focus on the Akron Innerbelt, an infamous highway project that significantly impacted historically Black neighborhoods. By examining the historical, economic, and social context of the Innerbelt, the project will identify the project's long-term impacts Akron communities. The goal is to use this knowledge to inform improve transportation equity in the affected areas by developing a plan for the Innerbelt since its vacancy in 2016. The project will …

Mobile Weather Satellite Receiver, Luke Datsko, Sam Watts, Jason Do, Adam Bechtler

Williams Honors College, Honors Research Projects

The "Mobile Weather Satellite Receiver" project aims to create a portable, user-friendly device that receives and displays weather information from geostationary satellites, addressing the limitations of traditional weather sources like the Internet and weather radio, particularly in remote areas. This device will collect and demodulate satellite data, including imagery and Emergency Managers Weather Information Network (EMWIN) forecasts, to provide users with detailed local forecasts and real-time alerts.

Designed with a user-centric approach, the system includes a satellite dish, Software Defined Radio (SDR), a Raspberry Pi, and a custom software interface for ease of use. Its portability and ability to function …

An Improved Method To Protecting Skin Graft Dressings Following Surgery In Severe Burn Patients, Andrew Martin, Matt Flaker, Hailey Essinger

Williams Honors College, Honors Research Projects

Severe burns, including deep second- and third-degree burns, affect over 450,000 people annually in the U.S., often requiring skin grafts for treatment. Recovery involves wearing wound dressings covered by bandage wraps for at least two weeks. While wraps are breathable, versatile, and simple, they can be painful to apply, especially for larger patients, and their compression varies based on the person applying them. This poses challenges when untrained caregivers are involved. Additionally, wraps often slip during physical therapy. Burn care units seek a new solution that matches current wraps in breathability and comfort but offers quicker application, controlled compression, and …

The Seating And Standing Arrangements Of Band, Orchestra, And Choir, Sabrina Wolf

Williams Honors College, Honors Research Projects

In this literature review, I will be looking for scholarly articles that discuss the seating and standing arrangements of band orchestra and choir ensembles. The main goal of this literature review is to find what information is available and discover what positions work to find the best sound that each ensemble can have. After finding the resources, I will annotate each source and summarize the information. I will also reach out to ensemble directors at the University of Akron and interview them to discover what seating and standing arrangements they prefer and why. I will compile this information into a …

An Aphasia Friendly Questionnaire For Post-Stroke Fatigue, Abigail Best

Williams Honors College, Honors Research Projects

A stroke is when there is lack of blood flow to part of the brain. It can cause permanent damage, such as paralysis, sensory changes, difficulty with speech and language (such as aphasia), and decreased memory. Within this project, we will discuss individuals post-stroke who are diagnosed with aphasia, which is the inability to understand and express language. Currently, there are minimal resources available to help a healthcare worker define and assess the fatigue level of a patient post-stroke who is also diagnosed with aphasia. The first objective of this research is to discuss stroke and aphasia. The second objective …

The Vital Role Of Interpreters In The Deaf Community: Navigating Accessibility Amidst Declining Deia Initiatives, Andrew Kovacs

Williams Honors College, Honors Research Projects

The catalyst for this research project stems from the rollback of Diversity, Equity, Inclusion, and Accessibility (DEIA) initiatives under the current presidential administration. Executive Orders from the presidential office have caused budget cuts and pauses in federal programs that affect all types of communities across the United States. For the Deaf community, funding for federal and state programs aimed at training ASL interpreters, helping Deaf individuals find jobs, and other communicative tools used by native signers has been paused. Despite the urgency of this issue, few studies have looked at the intersection of Deaf accessibility and the decline of DEIA …

Hca Healthcare Gme Residencies, Hca Healthcare

All Program Promotional Materials and Information

No abstract provided.

Hca Healthcare Gme Pediatrics, Hca Healthcare

All Program Promotional Materials and Information

No abstract provided.

Hca Healthcare Gme Obgyn, Hca Healthcare

All Program Promotional Materials and Information

No abstract provided.

Hca Healthcare Gme Internal Medicine, Hca Healthcare

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No abstract provided.

Explaining Constitutional Copying As An Idealogy: Argentina's "Yankee-Mania" Under President Domingo Sarmiento (1868-1874), Jonathan M. Miller

Minnesota Journal of International Law, Vols. 28:2 onward (2019-present)

Foreign constitutional models can transform a country thanks to the power of ideology. The comparative constitutional literature maintains that successful constitutionalism requires credible commitments to essential rules by all major political actors so that those out of power can avoid persecution that will drive them into rebellion, and those in power can feel assured that if they relinquish power, the opposition will respect their core interests. The literature also assumes that the process of reaching credible commitments is a slow one, but that over time civil society, courts and government bureaucracies will strengthen the commitments and act against unconstitutional power …

Deep Learning-Assisted Diagnostic System: Apices And Odontogenic Sinus Floor Level Analysis In Dental Panoramic Radiographs, Pei Yi Wu, Yuan-Jin Lin, Yu-Jen Chang, Sung-Tsun Wei, Chiung An Chen, Kuo-Chen Li, Wei-Chen Tu, Patricia Angela R. Abu

Department of Information Systems & Computer Science Faculty Publications

Odontogenic sinusitis is a type of sinusitis caused by apical lesions of teeth near the maxillary sinus floor. Its clinical symptoms are highly like other types of sinusitis, often leading to misdiagnosis as general sinusitis by dentists in the early stages. This misdiagnosis delays treatment and may be accompanied by toothache. Therefore, using artificial intelligence to assist dentists in accurately diagnosing odontogenic sinusitis is crucial. This study introduces an innovative odontogenic sinusitis image processing technique, which is fused with common contrast limited adaptive histogram equalization, Min-Max normalization, and the RGB mapping method. Moreover, this study combined various deep learning models …

Precision Medicine Assessment Of The Radiographic Defect Angle Of The Intrabony Defect In Periodontal Lesions By Deep Learning Of Bitewing Radiographs, Patricia Angela R. Abu, Yi Cheng Mao, Yuan Jin Lin, Chien Kai Chao, Yi He Lin, Bo Siang Wang, Chiung An Chen, Shih Lun Chen, Tsung Yi Chen, Kuo Chen Li

Department of Information Systems & Computer Science Faculty Publications

In dental diagnosis, evaluating the severity of periodontal disease by analyzing the radiographic defect angle of the intrabony defect is essential for effective treatment planning. However, dentists often rely on clinical examinations and manual analysis, which can be time-consuming and labor-intensive. Due to the high recurrence rate of periodontal disease after treatment, accurately evaluating the radiographic defect angle of the intrabony defect is vital for implementing targeted interventions, which can improve treatment outcomes and reduce recurrence. This study aims to streamline clinical practices and enhance patient care in managing periodontal disease by determining its severity based on the analysis of …

A Novel Real-Time Threshold Algorithm For Closed-Loop Epilepsy Detection And Stimulation System, Liang Hung Wang, Zhen Nan Zhang, Chao Xin Xie, Hao Jiang, Tao Yang, Qi Peng Ran, Ming Hui Fan, I. Chun Kuo, Zne Jung Lee, Jian Bo Chen, Tsung Yi Chen, Shih Lun Chen, Patricia Angela R. Abu

Department of Information Systems & Computer Science Faculty Publications

Epilepsy, as a common brain disease, causes great pain and stress to patients around the world. At present, the main treatment methods are drug, surgical, and electrical stimulation therapies. Electrical stimulation has recently emerged as an alternative treatment for reducing symptomatic seizures. This study proposes a novel closed-loop epilepsy detection system and stimulation control chip. A time-domain detection algorithm based on amplitude, slope, line length, and signal energy characteristics is introduced. A new threshold calculation method is proposed; that is, the threshold is updated by means of the mean and standard deviation of four consecutive eigenvalues through parameter combination. Once …

Electronic Health Records In Non-Hospital Settings Of Developing Economies: A Systematic Review On Enablers And Barriers, Bejie Rodriguez, Joenelyn Kaye Demoral, Jan Jacob Carpio, Alan Napoleon Gultia, Gloria Shiela Coyoca, Cecilio Garciano, Lemuel Clark Velasco

Institute of Philippine Culture (IPC)

In recent years, rapid advancements in Information and Communications Technology (ICT) have greatly transformed the healthcare landscape by streamlining health data management and providing decision-makers with secure and convenient access to health records. In developing economies, limited resources hinder healthcare access. Implementing EHRs in non-hospital settings is essential for enhancing healthcare quality and accessibility. While existing literature supports EHR use, further research is needed to pinpoint specific barriers and enablers. Using PRISMA guidelines, 18 relevant articles were systematically analyzed with the Human, Organization, and Technology Fit (HOT-fit) framework to examine these factors in non-hospital settings within developing economies. This study …

Use Of The Slur “Retard” Triples On X After Elon Musk Shares The Word In A Post, Bond Benton, Daniela Peterka-Benton

College of Communication and Media Scholarship and Creative Works

A joint study from Montclair State University faculty in the Joetta Di Bella and Fred C. Sautter III Center for Strategic Communication in the School of Communication and Media and the Department of Justice Studies shows that Elon Musk dramatically increased content containing the slur “retard” on X after using the term in a post. Highlights from the study include:

• A 207.5% increase in posts containing the r-word on X.
• 312,642 posts using the term r-word identified in the period studied.
• Google Trends Analysis showed a similar increase in online search activity related to the r-word.
• Indication of a broader …

Pride Month Support Can Generate 320% More Positive Social Media Posts For Companies; Dropping Support Can Increase Online Negativity By 165%, Study Finds, Bond Benton, Yi Luo, Jin-A Choi

College of Communication and Media Scholarship and Creative Works

A study from Montclair State University faculty in the Joetta Di Bella and Fred C. Sautter III Center for Strategic Communication in the School of Communication and Media showed the ongoing commitment to Pride Month by Universal Studios has been received positively online. In contrast, Target’s rolling back of support for Pride Month and diversity/inclusion elicited negative reactions in social media. Results show 320% more positive emotional sentiment in posts about Universal’s #loveisuniversal campaign, with 85% of posts advocating #BoycottTarget expressing negative emotions towards the company including anger, disgust, fear, and sadness. #BoycottTarget posts also contained 165% more negative emotions …

“R-Word” Slurs Triple On X After Donald Trump’S Thanksgiving Post Used The Word, Bond Benton, Daniela Peterka-Benton

College of Communication and Media Scholarship and Creative Works

A joint study from Montclair State University faculty in the Joetta Di Bella and Fred C. Sautter III Center for Strategic Communication in the School of Communication and Media and the Department of Justice Studies shows a dramatic increase in content containing the slur “retard” on X after Donald Trump’s Thanksgiving Day Truth Social post used the word. Findings showed a 225.7% increase in posts containing the r-word on X with 1,129,438 posts in the studied period. The most viewed, liked, and shared content analyzed enthusiastically endorsed use of the r-word. Results appear consistent with the period after other prominent …

If The Purpose Of The Tennessee Health Care Liability Act Is To Block Access To The Courts, Then It Is Succeeding—But “Surely, That Is Not The Intent Of Our Elected Representatives”, Kelsey L. Mcclain

University of Memphis Law Review

No abstract provided.

A Design-Focused Approach To Legal Argument And The Logical Fallacy Of Equivocation, Stephen M. Rice

University of Memphis Law Review

No abstract provided.

Consensus Templates, Jorge L. Contreras, Liane Hancock

Case Western Reserve Law Review

No abstract provided.

Relational Contracting And International Technology Transfer, Peter Lee

Case Western Reserve Law Review

No abstract provided.