Digital Commons Network^™

Expanding Transmobilities: Understanding Genderdiverse And Transgender Travel Behavior Through An Art-Informed Methodology, Nicholas Michael Puczkowskyj

Dissertations and Theses

Transgender and genderdiverse people face discrimination and harassment in public when making trips in Portland, OR. People who identify as genderdiverse or transgender create unique travel behavior due to the influence of their internalized and expressed gender identity and through interactions in public. This dissertation examines how gender identity influences the travel behavior of genderdiverse and transgender people and how these experiences influence their subjective wellbeing when making trips in Portland, Oregon. Traditional one-on-one interviews were conducted in conjunction with allowing the interviewees to produce art as a non-verbal form of expression and communication of their experiences making trips in …

Profiles Of Family Engagement In Head Start, Elizabeth Jane Tremaine

Dissertations and Theses

Families of young children are active participants in their child's transition to kindergarten. Head Start is designed to facilitate families' engagement in their child's learning experiences (Head Start Parent, Family, and Community Engagement Framework, 2018). This study explores family engagement in Head Start, its changes across the transition into kindergarten, and its relation to children's development of social-emotional and executive function skills.

The current study addresses limitations of previous research by relying on family perspectives of family engagement, approaching family engagement as a developmental concept, and taking a person-centered analytic approach that accounts for the multi-dimensionality of family engagement. This …

Trends In Non-Profit Cybersecurity: Analyzing Three Years Of Incident Data From The Npcir, Stanley Mierzwa, Joanna Paliszkiewicz, Edyta Skarzyńska

Center for Cybersecurity

This study analyzes cyberattack trends targeting non-profit organizations using longitudinal data collected over a three-year period within the Non-Profit Cybersecurity Incident Repository (NPCIR). Developed through a National Security Agency Center of Academic Excellence in Cyber Defense (NSA CAE-CD) designated center, the NPCIR applies an open-source intelligence (OSINT) methodology to systematically document cybersecurity incidents affecting the global non-profit sector. This study examines attack types, threat actor characteristics, sectoral distribution, and cybersecurity impacts using the Confidentiality–Integrity–Availability (CIA) triad framework. The results indicate that availability-related incidents, particularly ransomware and distributed denial-of-service (DDoS) attacks, constitute the most prevalent threats, while confidentiality breaches remain highly …

Decoding Growth Hormone Actions On Human Growth Plate Stem Cells, Shion Orikasa, Noriaki Ono

Faculty, Staff and Student Publications

The epiphyseal growth plate is the key target of growth hormone (GH) therapy. Although growth plate stem cells are well defined in mice, their presence in humans was unclear. Using rare surgical specimens, the study by Chu et al. reveals conserved, GH-responsive stem cells in the human pubertal growth plate.

Thermovision 3d, Daniel Louie, Iker Mendiburu Perez, Kieran Greeley

Interdisciplinary Design Senior Theses

This project presents the development of a three-dimensional thermal mapping system designed to identify energy inefficiencies in buildings. By integrating visible-light imaging with thermal sensing, the system generates detailed 3D models that visualize both structural features and heat distribution. Using photogrammetry techniques, overlapping images are processed to reconstruct building geometry, while thermal data is mapped onto the model to highlight areas of potential heat loss such as insulation gaps, windows, and structural joints.

The system combines hardware and software components, including a dual-camera setup and a custom visualization pipeline, to produce both qualitative and quantitative outputs. Users are able to …

The Shrinking Caspian Sea: Eco-Hydrological Responses To Human And Climate Pressures, Jesse Duku, Mohammad J. Tourian, Marzi Azarderakhsh, Rovshan Abbasov, Ali Mehran, Ali Torabi Haghighi, Stefanos Xenarios, Azara Boschee, Salih Babagiray, Mojtaba Sadegh, Nima Shokri, Ali Nazemi, Alireza Farahmand, Samaneh Ashraf, Temur Khujanazarov, Elmira Hassanzadeh, Dalal Najib, Daniel Placht, Shamshagul Mashtayeva, For Full Author List, See Comments Below

Faculty Research, Scholarly, and Creative Activity

The Caspian Sea, the Earth's largest inland water body, faces water level decline, drawing comparisons to the collapse of the Aral Sea. Unlike the Aral Sea, the relative roles of climatic variability, hydrological changes, and anthropogenic pressures on the Caspian Sea remain poorly understood. Here, we integrate satellite observations, in situ hydrological records and reanalysis data to examine recent drivers of the Caspian water loss. We show that total river inflow to the Caspian Sea has declined significantly, primarily due to reduced discharge from the Volga River. At the same time, precipitation over the basin has remained broadly stable, while …

Extraction Of Key Themes In Online Health Discourse Using Unsupervised Learning And Large Language Models, Miranda G. Scully

Computer Science Senior Theses

Health online discussion boards are a modern platform that allow patients to interact with each other and the healthcare system as a whole, making them valuable sources of information for clinicians seeking to better anticipate treatment experiences and barriers. This study focuses on one such community, r/suboxone, a subreddit where patients using Suboxone share their experiences and ask questions. Our analysis is motivated by previous work that proposes event-based classification systems for such posts which buckets posts from r/suboxone into one or more of five high-level labels (Access Logistics, Co-Occurring Drug Usage, Medication for Opioid Use Disorder Administration, Psychophysical Effects, …

Rehabvr: A Virtual Reality System For Upper-Body Orthopaedic Physical Therapy Rehabilitation, Winnie Brenda Wanjiru Waiya

Computer Science Senior Theses

Physical therapy is a central component of rehabilitation for musculoskeletal conditions, yet adherence to prescribed treatment remains persistently poor. Jack et al. identified pain, boredom, and insufficient feedback as key barriers to treatment adherence in physiotherapy outpatient settings,¹ and Rucinski et al. confirmed that non-adherence rates in orthopaedic populations remain between 50 and 70%, with patients who disengage facing elevated risk of reoperation, progressive functional decline, and poor clinical outcomes.² According to the World Health Organization, approximately 1.71 billion people globally live with musculoskeletal conditions,³ with shoulder pain specifically carrying a community prevalence ranging from 0.67 to 55.2% worldwide and …

Cardozo Law News Brief: June 5, 2026, Benjamin N. Cardozo School Of Law

Cardozo Law News Briefs

Highlights from the June 5, 2026 Cardozo Law News Brief include:

• The Cardozo Center for Public Service Law honored public-service leaders and advocates at its 34th annual INSPIRE! Awards, celebrating individuals whose work advances Cardozo’s public-service mission.
• Professor Wilfred Codrington III spoke to News From the States and appeared on NPR to discuss the Purcell Principle and the Supreme Court’s role in election-related litigation and redistricting disputes.
• Professor Lindsay Nash authored an op-ed in Lawfare arguing for greater judicial oversight of immigration arrests conducted through administrative warrants.
• Professor Alexander Reinert spoke to the Santa Fe New Mexican about the challenges …

Frontal Release Signs And Future Decline In Research Participants With Intact Cognition, Lauren G. Bojarski, Gregory A. Jicha, Elif Pinar Coskun, Frederick A. Schmitt, Linda Van Eldik, Erin L. Abner

Neurology Faculty Publications

Importance Frontal release signs (FRS) are primitive reflexes that regress with brain maturation and reappear in the setting of brain injury or neurodegeneration. Despite their association with dementia, the prognostic utility of this finding in the setting of early cognitive decline and preclinical disease is poorly understood. Objective To evaluate the association of FRS with future cognitive decline in research participants. Design, Setting, and Participants This cohort study examined the presence of FRS (from 2005-2024) among research cohort participants with intact cognition or mild impairment at study baseline. The study used single-center data collection of longitudinal research cohort data through …

Why Are Some Children Under 24 Months Still Undernourished In Urban And Peri-Urban Vientiane? A Mixed-Methods Study, Kethmany Ratsavong, Dirk Essink, Pamela J. Wright Phd, Ms, Med, Rn, Cen, Somphou Sayasone, Sengchanh Kounnavong, Jacqueline E. Broerse

Publications

Child undernutrition remains a significant public health challenge in many low and middle-income countries (LMICs), including Lao PDR, where high levels persist even in urban areas with generally available and accessible food. This study aimed to explore factors underlying the persistently high rates of undernutrition among young children in urban (Saysetha) and peri-urban (Pakgneum) districts of the Vientiane Capital in Lao PDR. A cross-sectional survey employed a sequential explanatory mixed-methods approach, combining a structured questionnaire of 333 mother-child pairs for quantitative analysis with semi-structured interviews of 47 caregivers for qualitative insights. The prevalence of malnutrition among children under 24 months …

Climate Deregulation Under Trump 2: Will It Have Any Durable Impact?, John D. Graham

Duke Environmental Law & Policy Forum

Following through on his 2024 campaign pledges, President Donald Trump is dismantling President Biden's aggressive climate policies, including federal regulatory controls on the major sectors of the economy that account for most greenhouse gas emissions in the US. Although it is too early to make a definitive assessment of what Trump will accomplish, I present evidence that Trump is taking a more creative, radical, and legally sophisticated approach to climate deregulation in his second administration than was attempted in his first administration. I evaluate how durable climate deregulation may be. A major weakness in Trump's agenda is the lack of …

The Civil Liability Gap For Oil Spills Caused By Non-State Armed Groups: The Case Of The Mv Sounion Tanker In The Red Sea, Emery Hansell

Duke Environmental Law & Policy Forum

On August 21, 2024, the Greek-flagged oil tanker MV SOUNION ("Sounion") was attacked by Houthis as it passed through the Red Sea. The Houthis, a rebel group that controls large swaths of Yemen, then set the ship ablaze, threatening to spill roughly 1 million barrels of crude oil into the water. The cleanup was anticipated to cost $20 billion. The question thus arises: who would—and who should—pay for that cleanup? At the moment, there is no effective solution.

As an initial matter, current international law focuses on State liability and is therefore unlikely to require the Houthis—as a non-State actor—to …

Phasing Out A Way Of Life: How Decarbonization Affects Coal Dependent Communities, Alex Loeb

Duke Environmental Law & Policy Forum

As member states seek to comply with European Union industry rationalization directives that will force mines that cannot compete with free-market prices without subsidies to close, domestic governments across Europe will face competing pressure from civil society. Many traditional European mining communities are dependent on the coal industry and will resist the phase out of its position in the European energy mix. In Asturias, Spain, the phase out of non-competitive coal mines has had devastating impacts on former mining towns, as they struggle to transition to a coal-free economy. After phasing out coal, Asturias has struggled with unemployment and significant …

The Perspectives Of Lesbian, Gay, Bisexual, Transgender, Queer/Questioning, Plus (Others) Teachers On The Enactment Of Their Identities At Work Amid Adverse Legislation, Mandy Rhea Manning

Walden Dissertations and Doctoral Studies

No abstract provided.

Item Selection Rules For Content Adaptive Progress Testing, Gergo Pinter, Nuno Santos, José Miguel Pêgo, Daniel Zahra, Steven Burr

Peninsula Medical School

Content adaptive progress testing (CAPT) introduces a new approach to longitudinal testing of candidates who take progress tests as part of their educational program. CAPT assessments adapt between subsequent assessments, tailoring items on an individual level to assist each candidate in demonstrating knowledge across many topics which are all mapped to the overall course learning outcomes. In this way, success is measured by topic completion on an individual level. Some of the key benefits include a truly personalized learning experience, with individual feedback throughout, while also tracking each candidate’s progress against a single long-term goal of demonstrating attainment across all …

Common Octopus (Octopus Vulgaris) Blooms Off The Southwest Of The Uk: History, Trends, Causes And Consequences.: Report On Work Package 2: Fisheries Independent Estimates Of Octopus Abundance And Behaviour., Bryce Stewart, Alice Hall, Tully Osmond, Keith Hiscock, Simon Thomas, Emma Sheehan

School of Biological and Marine Sciences

Since early 2025, a nearly unprecedented bloom of common octopus (Octopus vulgaris) has occurred off the southwest UK coast. Although native to UK waters, the species is usually rare, making this the largest bloom recorded in at least 75 years. While many octopus have been commercially landed, they have also preyed heavily on economically important shellfish species, including brown crab, European lobster and king scallop. Landings of these species declined sharply in 2025, causing significant hardship for many in inshore fishing communities. In response, a rapid research project was commissioned in August 2025 to investigate the history, causes and impacts …

Recommendations For Disclosure Of Artificial Intelligence In Scientific Writing And Publishing: A Regional Anesthesia And Pain Medicine Modified Delphi Study, Michael R Fettiplace, Anuj Bhatia, Yian Chen, Steven L Orebaugh, Michael Gofeld, Rodney A Gabriel, Daniel I Sessler, Hannah Lonsdale, Brittani Bungart, Christopher P Cheng, Garrett W Burnett, Lichy Han, Matthew Wiles, Steve Coppens, Thomas Joseph, Kristin L Schreiber, Thomas Volk, Richard D Urman, Vesela P Kovacheva, Christopher L Wu, Edward R Mariano, Vivian H Y Ip

Faculty, Staff and Student Publications

Introduction: The use of artificial intelligence (AI) in the scientific process is advancing at a remarkable speed, thanks to continued innovations in large language models. While AI provides widespread benefits, including editing for fluency and clarity, it also has drawbacks, including fabricated content, perpetuation of bias, and lack of accountability. The editorial board of Regional Anesthesia & Pain Medicine (RAPM) therefore sought to develop best practices for AI usage and disclosure.

Methods: A steering committee from the American Society of Regional Anesthesia and Pain Medicine used a modified Delphi process to address definitions, disclosure requirements, authorship standards, and editorial oversight …

Monoclonal Antibodies Targeting Pcdh7 Inhibit Tumor Growth And Enhance Immune Responses In Kras-Mutant Non-Small Cell Lung Cancer, Nicole Novaresi, Poorva Ghosh, Shayna Thomas-Jardin, Hui Deng, Xuejun Fan, Zhiqiang Ku, Wei Xiong, Xiaorong Zhou, Jingfei Zhu, Huiyu Li, Mahesh S Padanad, Bethany Smith, Chul Ahn, John D Minna, Zhiqiang An, Ningyan Zhang, Kathryn A O'Donnell

The Brown Foundation: Institute of Molecular Medicine

We identified an important oncogenic role for protocadherin 7 (PCDH7), a cell surface protein frequently overexpressed in lung adenocarcinoma and associated with poor clinical outcome. Pcdh7 depletion reduces tumor burden and prolongs survival in KrasLSL-G12D; Tp53fl/fl mice. These findings nominate this cell surface protein as an actionable therapeutic target and highlight the therapeutic potential of PCDH7 inhibition for non–small cell lung cancer. We report the development and characterization of high-affinity anti-PCDH7 monoclonal antibodies (mAbs) that inhibit downstream mitogen-activated protein kinase (MAPK) pathway activation and suppress tumor growth in multiple mutant KRAS–driven models. A lead mAb (mAb7) sensitized tumors …

Amc-F1 Regulates Mitochondria-Autophagy Crosstalk Independent Of Nutrient Stress, Yuqin Wang, Raksha K Rao, Trung Vu, Ayano Sekine, Zhengmei Mao, Nami Mccarty

The Brown Foundation: Institute of Molecular Medicine

Mitochondria and autophagy are fundamental yet distinct regulators of cellular homeostasis. Here, we identify AMC-F1 (Autophagy-Mitochondria Coupling Factor 1; formerly TRIM44) as a central integrator of mitochondrial bioenergetics and autophagy. Using Amcf1 knockout and knock-in mouse models, we demonstrate that AMC-F1 bidirectionally regulates these pathways: its loss reduces mitochondrial respiration and autophagic flux, whereas its overexpression promotes mitochondrial elongation and increases autophagy independently of nutrient stress. Transcriptomic analyses reveal AMC-F1-dependent regulation of mitochondrial biogenesis programs that engage autophagy, involving mitochondrial respiratory chain complex genes under basal conditions and mitochondrial organization factors under starvation-induced autophagy. Although dispensable under homeostasis, this coupling …

Statistical Methods In Research, Horahenage Dixon Vimalajeewa

UNL Faculty Course Portfolios

This course portfolio documents the design, delivery, assessment, student-learning evidence, and reflective evaluation of STAT 801A-700: Statistical Methods in Research, an online asynchronous service course designed to introduce students from diverse disciplinary backgrounds to foundational statistical reasoning and applied data analysis. The course is a non-calculus-based introduction to statistical methods used to answer research questions, with emphasis on collecting, organizing, describing, analyzing, and drawing conclusions from data. The course also emphasizes applications relevant to biology, agriculture, and other research-oriented fields. This is an online distance course aimed to develop students’ understanding of basic probability and statistical concepts, recognize the importance …

Racism In The Science And Practice Of Psychotherapy, Richard E. Redding, Craig L. Frisby

Psychology Faculty Articles and Research

We discuss a recent controversy that occurred in The Cognitive Behavioural Therapist over whether Lilienfeld’s critical views on microaggressions theory and research reflect racist beliefs, as alleged by some. This is one of many recent examples of a profoundly antiscientific practice whereby racism allegations chill scientific debate and open inquiry on important research issues. This produces an overtly politicized science that has a corrosive effect on scientific progress and ultimately the useful application of research in clinical practice. The microaggressions controversy provides an especially useful vehicle for challenging this state of affairs given the widespread application of microaggressions theory, including …

The Employment Situation Of Veterans: May 2026, Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

The May 2026 employment report highlights improving labor conditions for U.S. veterans, with unemployment declining from 3.6% in April to 3.2% in May..pdf) Despite this progress, Post-9/11 veterans experienced a slight increase to 4.1%. Younger veterans continue to face higher unemployment rates than their nonveteran peers, while older veterans maintain relatively low rates. Long-term unemployment remains a concern, with over half of unemployed veterans out of work for 15 weeks or more. Unemployment decreased across most demographic groups, including women and minority veterans, often falling below nonveteran rates, indicating gradual but uneven improvement in veterans’ employment outcomes nationwide.

Uncovering Dkk1 As A Therapeutically Relevant Target In Aggressive Er+ Breast Cancer Using A Novel Antiestrogen, Kristen Young

Dissertations

Over 70 percent of breast cancers are estrogen receptor-positive (ERα+), meaning that the hormone estrogen drives tumor growth. Although first-line targeted therapies that directly block ERα from hormone-dependent pathologies are initially effective, almost half of patients ultimately progress. These patients show high mutational rates to the ESR1 gene that encodes for ERα. A hotspot missense tyrosine to serine mutation at position 537 (Y537S) initiates hormone-independent, allele-specific transcriptional programs that increase metastasis. While next-generation ERα-targeted therapies show promise, benefits are often limited compared to standard-of-care. Understanding the mechanisms of action used by the Y537S ESR1 breast cancer cells to evade therapeutic …

Discovery Of Bmi-Associated Gut Microbiome Signatures In The Awi-Gen 2 Cohort, Meriem Yagoubi

Theses and Dissertations

Obesity is increasing across sub-Saharan Africa amid rapid dietary, environmental, and urbanization transitions, yet the gut microbiome features associated with adiposity in African populations remain under-characterized. This study investigated whether species-level gut microbiome composition is associated with body mass index (BMI) in the AWI-Gen 2 cohort, and whether BMI-associated microbial signals remain detectable after accounting for the dominant geographic structure of the microbiome. Gut microbiome community structure and diversity were characterized across 1,665 participants, and differential abundance analysis was used to identify taxa associated with BMI after controlling for study site. Machine learning models were then trained to assess how …

Acceptance Of Shared Autonomous Vehicles: Exploring The Attitudes And Perspectives Of Older Adults, Sara Sohaee Urbina

Dissertations and Theses

The fast development of autonomous vehicle systems will create major changes in how people move around. Previous research shows that these technologies can benefit older people who struggle with mobility, safety and access to transportation. Shared Autonomous Vehicles (SAVs) enable older people to achieve self-reliance while obtaining essential services which enhance their quality of living. The successful deployment of SAVs requires users to accept this new technology which they must also be willing to use. This research study investigates which elements affect older adults to adopt SAVs by using an extended Technology Acceptance Model (TAM) framework.

The research design of …

Disease-Causing Mfn2 Mutants Impair Mitochondrial Fission Dynamics By Distinct Drp1 Dysregulation, Daniel Lagos, Pamela R. De Santiago, Nicolás Pérez-Bravo, Benjamín Cartes-Saavedra, Josefa Vial-Brizzi, Diego Troncoso-Chandía, Oliver Podmanicky, Rita Horvath, Verónica Eisner

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Mitochondria undergo fusion and fission. While DRP1 regulates fission, fusion is controlled by OPA1, MFN1, and MFN2. The balance between these processes and the crosstalk between machineries remains poorly understood. MFN2 mutations cause Charcot-Marie-Tooth disease type 2 A (CMT2A), affecting mitochondrial fusion and morphology. However, their role in fission is unclear. Using skin fibroblasts from CMT2A patients (L248H and M376V MFN2 mutations) and wild-type mouse embryonic fibroblasts expressing these variants, we studied how MFN2 mutations impact mitochondrial dynamics beyond fusion. We analyzed mitochondrial morphology and dynamics by live-cell confocal microscopy and tested fusion/fission protein levels, oxygen consumption rate (OCR), extracellular …

Office Discipline Referral Narratives, Context, And Categorization, Deanna M. Bush

Education Dissertations

This two-part qualitative study examined the experiences of students with disabilities (SWD) in the middle school discipline. Phase one was a qualitative document analysis study that examined school discipline for SWD through the lens of Critical Disability Theory (CDT), Multi-Tiered Systems of Support (MTSS), Constructivist Learning Theory, and the Vulnerable Decision Point model (VDP) in a midsize suburban district in Washington state. The study explored alignment of ODR teacher-written narratives with behavioral categories assigned to the ODR at the time of issue to determine variance based on behavior category or student disability status. Phase two a semi-structured interview (shown on …

Targeted Reflex Rna Sequencing For Enhanced Variant Classification On Exome And Genome Sequencing Improves Patient Outcomes, Xiaonan Zhao, Robert Rigobello, Morgan Driver, Sydney Lau, Mei Ling Chong, Jason Chibuk, Hongzheng Dai, Wilson C W Wu, Christina Peroutka, Laura Famularo, Alexander Y Kim, Bailey Hummel, Sarah Dugan, Tinsley Douglas, Linyan Meng, Fan Xia, Christine M Eng

Faculty, Staff and Students Publications

RNA sequencing (RNA-seq) has been utilized to provide functional evidence regarding the impact of splicing variants. This study explores the utility of targeted reflex RNA-seq to inform classification of predicted splicing variants identified through clinical exome sequencing (ES) and genome sequencing (GS). A retrospective analysis was conducted on consecutive ES/GS cases completed at a single center in which targeted reflex RNA-seq was performed following identification of eligible variants. There were 131 cases (4.1%) that had at least one RNA-seq eligible variant reported, with eight of these cases having two unique eligible variants. Of the 139 eligible variants, 125 were classified …

Participants’ And Physiotherapists’ Views On The Delivery Of A Randomised Controlled Feasibility Trial Investigating A Bespoke Dynamic Elastomeric Fabric Orthosis For Women With Chronic Pelvic Girdle Pain: A Qualitative Exploration, Bradley Halliday, Jennifer Freeman, Sarah Chatfield, Lee Cameron, Kirsty Carter, Joanne Hosking, Jill Shawe

School of Health Professions

Background: Chronic pregnancy-related pelvic girdle pain (PPGP) affects approximately 10–30% of postpartum women beyond 3 months. Such pain is typically recalcitrant to standard care. A dynamic elastomeric fabric orthosis (DEFO) is one option. A feasibility randomised controlled trial (fRCT) assessed the feasibility and acceptability of trial design, interventions and data collection. The aim of this qualitative sub-study was to explore the experience of women participating in the feasibility trial, and physiotherapists delivering the trial intervention. Methods: An embedded qualitative study within a fRCT. The fRCT randomised participants to either control (standard care involving advice and exercise) or intervention (standard care …