Digital Commons Network^™

Canadian Gaar And Statutory Interpretation, Jinyan Li, Joanne Magee

All Papers

The Canadian GAAR is an anti-abuse rule that denies the tax benefit resulted from abusive avoidance transactions. This paper examines the history, technical design, policy objectives and judicial interpretation of the GAAR. It explains the role of the new preamble and economic substance in applying the GAAR.

Freedom Of Peaceful Assembly Under Section 2(C) Of The Charter: A Call For Action, Jamie Cameron

All Papers

“A Call for Action” builds on the author’s previous work on s.2(c) for the Rouleau Commission (“Freedom of Assembly and Section 2(c) of the Charter”; available on SSRN and Osgoode Digital Commons). There is no framework of legality under the Charter for the scope and limits of peaceful assembly, and this follow-up paper begins the task of filling that gap. It addresses the relationship between s.2(b) and s.2(c), critiquing the “factual matrix principle” for subsuming issues freedom of assembly into freedom of expression, and explaining that assembly is a distinctive collective entitlement that is spatial and performative in nature. …

What Is The Standard Of Review For (Mixed) Constitutional Questions?, Anthony R. Sangiuliano, Mark Friedman

All Papers

According to the framework for selecting the standard of review in civil appeals developed in Housen v Nikolaisen, questions of mixed fact and law are reviewed on a standard of palpable and overriding error. This framework applies to allegations that a statute is constitutionally invalid. However, in Société des casinos du Québec inc v Association des cadres de la Société des casinos du Québec, the Supreme Court held that when a statute is challenged as unconstitutional before an administrative tribunal, questions of mixed fact and law are subject to a correctness standard on judicial review as an exception to the …

Mailing It In: Due Process Requires Technology-Driven Safeguards In Public Benefits, Eric Lukoff

Celebrating WCL Student Authors

Due process in safety net public benefit programs requires agencies to employ modern technology in providing notice that is reasonably likely to reach participants. The Supreme Court has held that due process is dependent on the time, place, and circumstances in which it operates. Scholars have further argued that due process is adaptable to changing facts and circumstances over time. Yet, mailed paper notices remain the standard in providing notice to participants in public benefit programs.

Living in poverty today looks significantly different than it did nearly fifty years ago at the time of Mathews v. Eldridge, where the Court …

Labour Against The Law? Contesting The Restrictive Norms Of Industrial Legality Through Unlawful Strikes, Eric Tucker

All Papers

North American regimes of industrial legality provide workers with protected rights to organize, bargain collectively and strike. However, they also limit the freedom to strike. Trade unions commonly accept and enforce these limits, but at great cost to solidarity and militancy. This article examines the many ways law works against labour by restricting the freedom to strike and explores the practice of unlawful strikes in North America, including recent examples that resulted in successful outcomes. It concludes with reflections on the revival of unlawful strikes as a tactic for rebuilding and remobilizing the North American labour movement. While the article’s …

Decoding Heterogeneity In Human Aging: Omic Biomarkers Of Age-Related Disorders, Yaroslav Markov

Yale Graduate School of Arts and Sciences Dissertations

Biological aging unfolds along multiple heterogeneous trajectories shaped by both acquired molecular drift and inherited genetic variation. This dissertation investigates two complementary axes of aging heterogeneity: (1) stochastic, individually acquired epigenomic deviations; and (2) genotype-defined risk exemplified by the APOEε4 allele, the strongest genetic determinant of late-onset Alzheimer’s disease (AD).

1) Stochastic Epigenetic Mutation Detection

We developed SEMdetectR, a robust R-based pipeline for identifying and quantifying stochastic epigenetic mutations (SEMs) -- rare, outlier CpG methylation events that accumulate idiosyncratically with age. Using technical replicates from three independent cohorts, we uncovered previous methodological flaws undermining SEM reliability and trained a machine …

Social Factors Variably Predict Salivary Cortisol Levels In Tufted Capuchins, Aiko Amano

Master’s Theses

Glucocorticoids (GCs) have become a prime focus in studies involving the relationship between psychosocial factors and physiology. For social animals, determining the social variables that relate to both GC release and buffering can help tease apart the complex interplay between the psychological and physiological dynamics of individuals and their communities. A 2019 study found relationships between social factors and hair cortisol in a group of socially housed tufted capuchin monkeys in which social support correlated negatively with cortisol levels while received aggression correlated positively. The present study examined the relationships between similar social measures and salivary cortisol in the same …

Examining The Industrial Impact Of Fintech Lending In The Post-Next Normal Era, Nur 'Asyiqin Ramdhan, Imbarine Bujang, Amirul Afif Muhamat, Purwatiningsih Lisdiono

The Indonesian Capital Market Review

The financial sector has undergone a substantial paradigm shift as a consequence of the COVID-19 pandemic prompting industries actively innovate their financing method. Utilizing ARDL, our analysis reveals intriguing insights into the interaction of financing determinants interruptions caused by the epidemic, and the P2P lending success. The long-term effects of economic conditions alluding to the significant influence of investment size across various industrial sectors. The industrial differences suggest interesting connections between the size of investments, and loan tenure to the P2P lending in different industries. The wholesale and retail trade sector demonstrates intricate reactions to changes in investment size, while …

Chromosome Segregation Dynamics During Meiosis I, Meiosis Ii, And Mitosis Cell Divisions In Acheta Domesticus (House Crickets), Sweta Aryal

Master’s Theses

Chromosomes exhibit diverse types of organization and movement during the cell division process. Meiosis is essential for sexual reproduction, producing haploid cells from diploid precursors. In meiosis I, homologous chromosomes pair up, and separate in anaphase I, with two chromatids moving toward each pole. In meiosis II, the sister chromatids move to opposite poles during anaphase II and produce haploid cells. In contrast, in mitosis, the chromosomes are copied and distributed to produce genetically identical diploid somatic cells. Understanding the behavior of chromosomes during mitosis and meiosis is significant for accurate chromosome segregation to prevent birth defects and diseases like …

Evaluation Of Sex Trivalent Chromosome In Giant Shield Mantis (Rhombodera Megaera) And Holocentric Chromosome In Milkweed Bug (Oncopeltus Fasciatus), Hedyeh Davoudi Kianersi

Master’s Theses

Aneuploidy, which refers to the abnormal number of chromosomes within a haploid set, has a significant effect in both physical and cognitive process of development. Proper chromosome segregation during cell division is crucial to prevent aneuploidy. Chromosome segregation is affected by the alignment of chromosomes on the metaphase plate as well as the position of centromere on the chromosome. Many arthropod species have sex chromosomes that either naturally are unpaired or pair in ways that differ for the usual patterns for autosomes. Also, some arthropods possess unique centromere position on their chromosomes which directly affects chromosome segregation pattern. Evaluating the …

Biomedical Privacy And Security: Histology Image Vulnerabilities And Blockchain Solutions, Eric Ni

Yale Graduate School of Arts and Sciences Dissertations

Biomedical research increasingly relies on vast datasets, such as genomic sequences, electronic health records, and histology images, to advance scientific knowledge and clinical applications. However, the sensitive nature of biomedical data poses significant privacy risks, particularly with emerging capabilities of artificial intelligence and machine learning technologies. This dissertation addresses two central challenges in biomedical data privacy and security: quantifying privacy risks associated with histology images and developing innovative blockchain-based methods to ensure secure data storage and sharing.

The first part of this work investigates the vulnerability of histology images—commonly perceived as safe for public sharing—to privacy breaches. Utilizing advanced computational …

Sexual Labor, United States Immigration Law, And México's Emerging Feminist Consciousness, 1875-1925, Narcedalia Ramirez

Theses and Dissertations

This thesis is an intellectual, cultural, women’s, and transnational history between México and the United States that outlines the arguments over sex workers. At the forefront is how stories of sex workers intersect with the histories of moral and hygiene reform movements, and United States laws on immigration and morality during the years of 1875 to 1925. This body of work is in conversation with scholars such as Kelly Lytle Hernández. Susie S. Porter, and Diana Montaño.

Sources include United States legislation, Spanish written newspapers and studies on sex work from México, the Elena Torres Cuéllar Archives, the Margaret Sanger …

Black Adolecent Girls' Perceptions Of Dress Code Violations, Pat A. Carpenter

Theses and Dissertations

This study explored the experiences of Black adolescent girls at Wellington Middle School (pseudonym) regarding dress code policies and the disciplinary actions associated with their attire. Through the analysis of disciplinary data, qualitative interviews, and a review of relevant literature, the research aimed to uncover potential racial biases within dress code policies and their enforcement. Preliminary insights indicated that such measures may contribute to broader patterns of racial discrimination and inequity in the education system, impacting the academic and social development of these students. The study goals were to emphasize the need for policy reforms and advocate for the development …

Water Tent: Implementation Guide Grades 3-8, Beth Young, Alicia Carlson, Haley Wicklein

Earth Around Us

No abstract provided.

Water Tent: Implementation Guide Grades K-2, Beth Young, Alicia Carlson, Haley Wicklein

Earth Around Us

No abstract provided.

Exploring Physicians/Physician Assistants Perspectives On The Challenges And Communication Approaches When Communicating With People With Aphasia, Alexandra M. Rogers

SURF Posters 2025

Aphasia is an acquired language disorder that results from damage to the language areas of the brain, typically located within the left hemisphere. Individuals with aphasia often experience significant challenges while communicating with other individuals, including physicians and healthcare professionals. These barriers can ultimately lead to negative impacts on the quality of care, patient experiences, and overall health outcomes. The lack of consistent use of communication strategies as well as a general misunderstanding of aphasia by medical staff, further contributes to communication breakdowns. As a result, medical assessments can be misinterpreted, treatments may be delayed, and patients may feel less …

Disentangling The Relationships Among Gender, Neighborhood Disadvantage, Depression, And Delinquency, Brooklyn Giovinazzo

SURF Posters 2025

The association between gender and crime or delinquency, with males committing more crime and delinquency than females, has been well-established in the criminological literature (e.g., Lauritsen et al. 2009; Kruttschnitt, 2013; Steffensmeier & Allen, 1996). This relationship has been consistently found across offenses, except for prostitution, across data sources, and over time. Despite this consistent association between gender and crime, or more broadly gender and deviance, this relationship is not fully understood. In part, this lack of understanding is a result, until relatively recently, of the paucity of research on girls’ deviance and delinquency. More recent research has demonstrated areas …

Queer Life In Nineteenth-Century America: A Historical Literature Review, Vivian Wright

SURF Posters 2025

In recent political discourses, queerness has often been treated as a modern phenomenon, and many people tend to think of queerness as a twentieth-century invention. Historians, however, have shown this to be false; an extensive amount of historical work details the lives of those who did not conform to sexual or gender norms in nineteenth-century America. This review surveys such works, analyzing nearly twenty different works spanning the course of nearly fifty years. By examining these works chronologically, the development of the field of queer history can be understood in the context of social and political developments occurring in the …

W423.3-026z-01 - College Of Education: Doctor In Education Program: Correspondence And Memoranda, College Of Education

University Archives Finding Aids

No abstract provided.

Electronic Resources Updates - 2024 Q4, Brigitte Galauner, Gregg Harris

Electronic Resources Quarterly Updates

No abstract provided.

Contact Pathway Factors As Potential Modifiers Of Bleeding Related To Factor Xi Deficiency, Ivy R. Han, Leah Rosenfeldt, Courtney Young, Bal Krishan Phd, Rachel Cantrell Phd, Cassie Sprague, Mousa Kharnaf, William Abplanalp, Joseph Palumbo Md

Williams Honors College, Honors Research Projects

Factor XI (FXI) deficiency, also known as Hemophilia C, is characterized by mild to moderate bleeding symptoms. However, the factors that modify bleeding severity in FXI deficiency are not fully understood. In this study, we investigated whether components of the contact activation pathway can act as modifiers of bleeding in the context of FXI deficiency. Using a tail vein transection (TVT) model in rats, we assessed bleeding in four experimental groups: wild-type Sprague-Dawley rats, Prekallikrein knockout (PKK^-/-) rats, rats treated with a FXI-inhibiting antibody, and PKK-/- rats treated with the FXI antibody.

Under anesthesia, each rat underwent a …

Analysis Of Sled Dog Biomechanics, Natalie Bender

Williams Honors College, Honors Research Projects

This paper is an analysis of data collected by Dr Rachel Olson and her team. The data was collected from the same set of sled dogs before and after training for the Iditarod race. The goal of this paper is to draw conclusions on whether the gait of sled dogs’ change with fitness level. The data was cleaned in R to find the average peak for forelimb joint angles per run for each dog. The data was analyzed with 3 different ANOVAs – one including both the shoulder and carpus, one for just the shoulder, and one for just the …

Time Series Modeling Of Akron Air Quality Index (Aqi) Data, Mason Yurich

Williams Honors College, Honors Research Projects

With the increase in population and industrialization around the world, climate has become a major concern for many researchers. One measure that has drawn much interest is air quality. There are available resources that track the Air Quality Index (AQI) in most large cities, but there is a general lack of information regarding Air Quality forecasts, even for one day in the future. This project aims to find a useful statistical model for representing and predicting the AQI measure in Akron, Ohio over time. By using historical air quality data from the United States Environmental Protection Agency and AQI.in, an …

Effects Of Diet Composition On Physical Parameters In Danio Rerio, Isabella Hemphill

Williams Honors College, Honors Research Projects

With the use of zebrafish as a common model organism for human health, the reduction of confounding variables in their care is key. Many commercialized zebrafish diets are available for purchase, but each one consists of a different ratio of these crucial macronutrients. This study aimed to determine the effects long-term diets high in one macronutrient would have on the morphometrics, heart, liver, and protein content of zebrafish. Four diets were fed over a period of almost two years- high lipid, high carb, high protein, and a control diet. The control diet was the standard feed used in this lab, …

An In-Depth Review Of Euthanasia-Related Practices, Arguments For/Against Them, And Proposed Solutions For Their Most Glaring Legal/Ethical Problems, Macon Plecha

Williams Honors College, Honors Research Projects

This paper’s goal is to cover the topic of euthanasia-related practices at great length. Terminology, history, and current programs around the world are discussed first, with the last point covering a wide geographical range: Colombia, Japan, Israel, and Africa, to name a few outside of the Western world standard. Arguments for and against euthanasia-related practices are explored. Within these arguments, several pressing legal and ethical issues arise, and the most severe of these are expanded on through the offering of potential solutions: how to handle stand-alone psychiatric cases, how to improve advanced directives and poor reporting rates, and how to …

Exploring Psychological Implications Of The Contemporary Lung Transplant, Isaac C. Machar

Williams Honors College, Honors Research Projects

Since its inception in 1963 at the University of Mississippi Medical Center, more than 50,000 lung transplant procedures have been performed. During its 50-year anniversary, 2023 saw just over 3,000 lung transplants performed in the United Sates. However, as this procedure continues to increase in execution each year, it is critical that the psychological implications of this procedure are explored. In this paper, I hope to develop an understanding of the psychological background of contemporary lung transplantation. Reviewing the lung and double lung transplant, the goal is to apply biopsychology principles to the field. Background information about transplant science is …

Improving Policies And Addressing Regulatory Barriers To Grow And Support Tennessee's Child Care Industry

Miscellaneous Reports

No abstract provided.

Parents In Action For Change, Faisuly Correa Rojas

Education | Graduate Culminating Projects

This handbook offers a structured framework for parents in Marin County’s advocacy group, aimed at informing them about special education and bullying prevention practices to better advocate for their children's education.

Improvement Of Cellular Pattern Organization And Clarity Through Centrifugal Force, Lauren E. Mehanna, James D. Boyd, Shelley Remus-Williams, Nicole M. Racca, Dawson P. Spraggins, Martha E. Grady, Brad J. Berron

Chemical and Materials Engineering Faculty Publications

Rapid and strategic cell placement is necessary for high throughput tissue fabrication. Current adhesive cell patterning systems rely on fluidic shear flow to remove cells outside of the patterned regions, but limitations in washing complexity and uniformity prevent adhesive patterns from being widely applied. Centrifugation is commonly used to study the adhesive strength of cells to various substrates; however, the approach has not been applied to selective cell adhesion systems to create highly organized cell patterns. This study shows centrifugation as a promising method to wash cellular patterns after selective binding of cells to the surface has taken place. After …

Integrating Protein Language Model And Molecular Dynamics Simulations To Discover Antibiofouling Peptides, Ibrahim A. Imam, Shea Bailey, Duolin Wang, Shuai Zeng, Dong Xu, Qing Shao

Chemical and Materials Engineering Faculty Publications

Antibiofouling peptide materials prevent the nonspecific adsorption of proteins on devices, enabling them to perform their designed functions as desired in complex biological environments. Due to their importance, research on antibiofouling peptide materials has been one of the central subjects of interfacial engineering. However, only a few antibiofouling peptide sequences have been developed. This narrow scope of antibiofouling peptide materials limits their capacity to adapt to the broad spectrum of application scenarios. To address this issue, we searched for antibiofouling peptides in the vast sequence pool of the microbiome library using a combination of deep learning-based high-throughput search and molecular …