Digital Commons Network^™

Development Of Welfare Assessment Strategies For Indonesian Zoos, Yonathan Yonathan

School of Biological and Marine Sciences Theses

Animal welfare assessment is a core element of zoo management, helping zoos achieve positive welfare state for their animals. Welfare should be assessed regularly to evaluate, monitor, and improve the standards of care. The research on welfare assessment and its development process increased after the World Association of Zoos and Aquariums (WAZA) launched the 2023 Animal Welfare Goals, which include mandatory welfare assessment process for national and regional zoo associations. In Indonesia, many zoos don’t have their own welfare assessment and find it difficult to adapt generic tools due to variation in husbandry, resources, and facilities. This project aims to …

How Do Human-Induced Environmental Stressors Shape The Distribution, Physiology, And Behaviour Of The Lemur Leaf Frog?, Benjamin Hough

School of Biological and Marine Sciences Theses

The Lemur leaf frog (Agalychnis lemur) is a critically endangered species of anuran whose survival is increasingly threatened by human-induced environmental stressors, such as habitat loss, fragmentation, and climate change. This study investigates how those stressors shape the physiology, distribution, and behaviour of the species through combinations of physiological and distributional modelling and a behavioural trial. The study uses a novel approach into understanding how future risk posed by climate change could impact Lemur leaf frogs. By using field spatial data combined with physiological mechanistic modelling, the study is able to predict how Lemur leaf frogs body temperature and geographical …

Effects Of Host-Derived Probiotics On The Growth Performance And Health Of Tilapia And Carp, Sherilyn Abarra

School of Biological and Marine Sciences Theses

To address the need for well-characterised probiotic strains for tilapia and carp aquaculture, this study investigated the isolation, characterisation, and application of host-derived candidate probiotics from Nile tilapia (Oreochromis niloticus) and mirror carp (Cyprinus carpio), and their influence on growth, feed utilisation, intestinal integrity and microbiome, and mucosal health of the host.A total of 263 intestinal bacterial isolates were screened in vitro for antagonism against Aeromonas hydrophila and Streptococcus iniae. The top 31 isolates with inhibitory effects underwent screening against three further fish pathogens and were assessed for haemolytic activity and extracellular enzyme production in …

Evaluating The Efficacy Of Brewers’ Yeast-Derived Functional Feed Additives In Mitigating Soybean Meal-Induced Enteritis In Atlantic Salmon, Taofik Adeiza Momoh

School of Biological and Marine Sciences Theses

Aquaculture continues to expand as a vital contributor to global food security, yet this growth introduces new challenges including the need to replace fishmeal with plant-based ingredients without compromising intestinal health. In Atlantic salmon aquaculture, one of the main constraints to plant protein inclusion is soybean meal-induced enteritis (SBMIE), a diet-related inflammatory condition that impairs mucosal function. Meanwhile, the use of functional feed additives such as those derived from brewers’ yeast (Saccharomyces cerevisiae) have emerged as a promising strategy to mitigate such diet-induced pathologies and support immune regulation. This thesis investigates the efficacy of structurally distinct brewers’ yeast-derived additives, including …

Considering Behaviour In Genetic Sampling – A Case Study With Grey Seals, Kathryn Wiltshire

School of Biological and Marine Sciences Theses

Genetic variations are increasingly linked to intra-specific behavioural variations. Advancing our knowledge of behavioural genetics could make screening populations for genetic polymorphisms associated with behavioural variations possible. Genetic-behaviour links have been increasingly discovered in terrestrial mammals, but there are few comparable studies in marine mammals. Developing efficient and cost-effective genetic sampling techniques is essential to allow more studies on behavioural genetics in lesser researched marine mammals. This study explores the potential of a sampling technique, still in its infancy in marine mammal studies, that has potential to cause minimal stress to the animals. Buccal swabs were tested in a group …

An Assessment Of The Dietary Bioavailability Of Tio2 And Inorganically Carbon-Based Nanomaterials In Rainbow Trout, Using The Ex Vivo Gut Sac Technique And A In Chemico Digestibility Assay, Craig Mchardy

School of Biological and Marine Sciences Theses

Abstract. Craig McHardyAn assessment of the dietary bioavailability of TiO2 and inorganically carbon-based nanomaterials in rainbow trout, using the ex vivo gut sac technique and a in chemico digestibility assay.Carbon based engineered nanomaterials (ENMs) are an emerging contaminant within modern society, as such their environmental risk assessment is of high importance. Testing for their persistence, toxicity and bioaccumulation potential is important for regulatory bodies to fully understand the hazard posed. To date, data on the bioaccumulation potential of these ENMs is lacking, especially within fish. A tiered approach to bioaccumulation testing has been posed in which precursory tests such as …

Impact Of Dietary Functional Yeast Additives On Growth Performance And Health Of Selected Key Aquaculture Species, Sheu Odu-Onikosi

School of Biological and Marine Sciences Theses

The aquaculture industry has witnessed remarkable growth in recent decades underscoring its crucial role in global food security. However, this rapid expansion brings challenges, including the need to meet growing fish demand while minimising environmental impacts and managing disease prevalence. Functional feed additives (FFAs) have emerged as sustainable solutions to enhance fish health and performance. Among these, yeast-derived additives have garnered significant attention for their nutritional benefits and proven ability to promote growth and strengthen immune responses in fish.This study evaluates the effects of dietary brewer's yeast-derived additives on fish using a range of in-depth analyses, such as growth performance, …

Vestibular Rehabilitation In Multiple Sclerosis: Randomized Controlled Trial And Cost-Effectiveness Analysis Comparing Customized With Booklet Based Vestibular Rehabilitation For Vestibulopathy, Jonathan Marsden, Rachel Dennett, Jennifer Freeman

School of Health Professions

Background:Vestibular dysfunction occurs in 30% to 70% of cases with multiple sclerosis (MS).Objective:To compare the clinical and cost-effectiveness of a customized vestibular rehabilitation (VR) program with a generic booklet-based VR intervention in people with MS with clinical signs of vestibulopathy.Methods:People with MS and symptoms of vertigo and/or imbalance were screened for vestibulopathy (n = 73). Seventy recruited participants were randomly allocated to a 12-week generic booklet-based home program with telephone support (n = 35) or a 12-week customized VR program (n = 35, 12 face-to-face sessions and a home exercise program). The primary clinical outcome was the Dizziness Handicap Inventory …

Maine Law Magazine - Issue No. 99, University Of Maine School Of Law

Maine Law Magazine

• A Letter from the Dean
• Alaskan residents granted resident tuition status at Maine Law
• ‘I wasn’t doing it alone’: Students find mentorship and direction in Maine Law’s 3+3 Program
• A Place to Call Home: Three journal symposium addresses housing crisis in Maine and beyond
• Maine Law community honors founding Dean Edward Godfrey’s lasting legacy
• How Maine Law’s Economic Justice Fellowship is Shaping the Next Generation of Advocates
• New fellowship broadens scope and reach of Maine Law’s Refugee and Human Rights Clinic
• The Clinics at Maine Law: Renamed to Reflect Our Expansive Reach
• Prisoners’ Assistance Clinic - Providing Much Needed Access …

Does Medial Tourism Promote Growth In Healthcare Sector?, Hassan F. Gholipour, Kourosh Esfandiar

Research outputs 2022 to 2026

The purpose of this study is to investigate the effect of medical tourism revenues on the growth of healthcare sector across 49 emerging and developed economies from 2008 to 2022. Using panel GMM and PMG/ARDL estimation methods, the results show that higher levels of medical tourism revenues promote growth in the healthcare sector. This finding remains robust across different sample periods, alternative measure of healthcare sector performance, and model specifications.

Draft Final Butte Priority Soils Operable Unit (Bpsou) Unreclaimed Sites: Ur-03 Site Remedial Action Work Plan (Rawp), Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Economic Behavior And Policy Distortions: Evidence From Firms And Households, Seth Joseph Carter

Graduate Theses, Dissertations, and Problem Reports (ETD)

In Chapter 1, I reopen the question of whether U.S. firms experience effective tax decreases directly resulting from federal lobbying expenditures by introducing more rigorous causal-inference testing. I first model lobbying as a productive input for the legislator, affecting firm tax outcomes by influencing the share of scarce legislative attention afforded to industry tax priorities. Using multi-industry, firm-level data from 2007 to 2022, I exploit percentage changes in non-industry lobbying as a proxy for political competition facing firms through a novel application of Bartik, shift-share instrumental variable estimation and two-stage residual inclusion. Effects of induced firm lobbying shifts on reported …

Developing A Simplified Method Of Measuring Ultrafine Particulate Matter Dose Concentrations For Diesel Emissions, Nafisat Ohunene Isa

Graduate Theses, Dissertations, and Problem Reports (ETD)

Abstract

Developing a Simplified Method of Measuring Ultrafine Particulate Matter Dose

Concentrations for Diesel Emissions

Ultra-fine particulate matter (UFP), particularly from diesel emissions, poses significant health and environmental risks due to its small size and potential to penetrate deep into the respiratory system. Accurate measurement of UFP concentrations is essential for assessing exposure and mitigating health impacts. However, current methods for measuring UFP can be complex, time-consuming, and costly. This study aims to develop a simplified method for efficiently measuring UFP concentrations from diesel emissions, which will enable easier and more widespread monitoring of air quality and public health impacts. …

Berkeley Pit And Discharge Pilot Project Quarterly Pilot Project Report Third Quarter 2024, Atlantic Richfield Company, Mark Thompson

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Teacher Becoming Of Alternatively Licensed Teachers, Erin Summerhays

Dissertations and Theses @ UNI

In the 2023-2024 school year, the Iowa Department of Education listed 21 teaching shortage areas. One way that more teachers can enter Iowa’s classrooms is through alternative licensure pathways. But these alternative programs need students who are willing to pursue the teaching profession, even knowing all of the challenges that today’s teachers face. The purpose of this study was to investigate why people choose to become teachers at a later point in their lives/careers, and to explore the mindsets of alternatively licensed teachers. The theoretical framework for this study includes Bakhtin’s theory on ideological becoming, interanimated discourses (Bakhtin, 1981; Gee, …

Check All That Apply: The Persistence And Problem Of The Black/White Racial Binary In Iowa Public Schools, Jessica Nessan Kluck

Dissertations and Theses @ UNI

The promotion of monoracial normativity has profoundly influenced the language used in policies, creating societal expectations that other the identification of Black/white Biracial and multiracial identities. Despite the reality of our quickly shifting demographics, multiracial identities continue to be marginalized and misconstrued through racial reporting guidelines. Racial reporting used on forms required by the Iowa Department of Education are comingled with non-racially categorized data to further distance reality in education and the public-school rankings (Iowa Department of Education, 2012; State of Iowa, 2024).

The purpose of this study was to trace the legacy of the socially constructed racial binary, preserved …

The Digital Loophole: Evaluating The Effectiveness Of Child Age Verification Methods On Social Media, Fatmaelzahraa Eltaher Ph.D, Rahul Gajula, Luis Miralles-Pechuán, Christina Thorpe, Susan Mckeever

Conference papers

Social media platforms are an integral part of daily life for nearly five billion people worldwide. However, the growing presence of underage users on these platforms raises significant concerns regarding children's exposure to harmful content and its impact on their mental health. This paper examines the effectiveness of age verification measures implemented on leading platforms Facebook, YouTube, Instagram, TikTok, Snapchat, and X. We evaluate the age verification processes required for account creation by simulating the registration steps for minors on these platforms. We also compare these methods to best practices in online age assurance in finance, betting and public transportation …

Bioinspired Gradient Porous Hip Implant Design To Prevent Stress Shielding Using Stress Mapping And Bone Remodeling Theory, Babak Ziaie, Xavier Velay, Waqas Saleem

Research Outputs: 2025-Present

Total Hip Arthroplasty (THA) is a widely performed surgical procedure, with increasing frequency worldwide. Despite its high success rate, many patients require revision surgeries due to complications such as aseptic loosening, primarily resulting from stress shielding, cortical hypertrophy, and micromotion. These issues often stem from a mechanical mismatch between the bone and the solid dense implant, particularly a mismatch in stiffness. A potential solution lies in the use of porous or lattice structures in implant design, which offer lower stiffness and improved biocompatibility by facilitating bone ingrowth, cell seeding, and vascularization. Among these designs, Triply Periodic Minimal Surfaces (TPMS), especially …

Conversations In The Classroom: Increasing Dialogic Inquiry To Dismantle Compliance-Based Teaching And Learning, Jill Rivera

West Chester University Graduate Theses, Dissertations, and Final Projects

Verbal interpersonal communication has been diminishing from the teaching and learning process over the past decade in public-school classrooms. School district administrations mandate teachers to utilize digital learning platforms and standardized tests due to the ease at which this technology can quickly gather data. While the transition to digital platforms and test-based education may be well-intended, the result has often been a decrease in dialogic inquiry-based pedagogy which removes teacher autonomy, student agency, and has negative effects on students’ ability to critically think and effectively engage in communication and instruction. The over-emphasis on collecting data based solely on a digitized …

Exploring Mental Health Concerns And Loneliness Among East Asian International Students In U.S. Universities, Shihan Xu

Antioch University Dissertations & Theses

This study examined the unique stressors encountered by international college students, with particular attention to East Asian international students, whose collectivistic cultural values contribute to their mental health status and reported symptoms. Following the COVID-19 pandemic, the rise in stress levels and loneliness highlighted the need for further examination. Using data collected in 2024 through the Counseling Center Assessment of Psychological Symptoms-34 (CCAPS-34) and the UCLA Loneliness Scale, the study surveyed East Asian international students enrolled in universities in the United States to identify prevalent mental health concerns and explore the correlation between loneliness and self-reported symptoms among East Asian …

21st-Century Stewardship: Infusing Environmental Education With Global Citizenship, Ava Y. Goodale

Antioch University Dissertations & Theses

In today's interconnected world, where socioecological issues transcend political borders, integrating environmental stewardship education with global citizenship education offers valuable opportunities for student empowerment. The goal of this multi-article dissertation was to conceptualize and operationalize 21st-century stewardship in educational settings. Twenty-first-century stewardship is a pedagogical approach that recognizes the limitations of environmental stewardship education as it is traditionally taught and is defined in Chapter II as an updated stewardship model that is infused with global citizenship’s multiscalar perspectives, global compacts, and layered identities to achieve its maximum impact in our interconnected world. This goal was first accomplished in Chapter II …

Patterns Of Inpatient Antibiotic Utilization By Race And Ethnicity At Us Children’S Hospitals, Bethany A. Wattles, Jeffrey I. Campbell, Theresa Kluthe, Yana B. Feygin, Kahir Jawad, Michelle D. Stevenson, Deborah Winders Davis, Jennifer Porter, V. Faye Jones, Matt Hall, Michael J. Smith

Biostatistics Faculty Publications

Background and Objectives: Racial and ethnic variations in antibiotic utilization are well-reported in outpatient settings but little is known about inpatient settings. Our objective was to describe national inpatient antibiotic utilization among children by race and ethnicity. Methods: This study included hospital visit data from the Pediatric Health Information System between 01/01/2022 and 12/31/2022 for patients <20 years. Primary outcomes were the percentage of hospitalization encounters that received an antibiotic and antibiotic days of therapy (DOT) per 1000 patient days. Mixed-effect regression models were used to determine the association of race-ethnicity with outcomes, adjusting for covariates. Results: There were 846,530 hospitalizations. 45.2% of children were Non-Hispanic (NH) White, 27.1% were Hispanic, 19.2% were NH Black, 4.5% were NH Other, 3.5% were NH Asian, 0.3% were NH Native Hawaiian/Other Pacific Islander (NHPI) and 0.2% were NH American Indian. Adjusting for covariates, NH Black children had lower odds of receiving antibiotics compared to NH White children (aOR 0.96, 95%CI 0.94–0.97), while NH NHPI had higher odds of receiving antibiotics (aOR 1.16, 95%CI 1.05–1.29). Children who were Hispanic, NH Asian, NH American Indian, and children who were NH Other received antibiotic DOT compared to NH White children, while NH NHPI children received more antibiotic DOT. Conclusions: Antibiotic utilization in children’s hospitals differs by race and ethnicity. Hospitals should assess policies and practices that may contribute to disparities in treatment; antibiotic stewardship programs may play an important role in promoting inpatient pharmacoequity. Additional research is needed to examine individual diagnoses, clinical outcomes, and drivers of variation.

A Demographic Description Of Children And Adolescents With Concomitant Autism And Anxiety Along With A Comparison Of Receipt Of Psychological Services, Elizabeth Salt, Amanda T. Wiggins, David N. Toupin, Emma Parks, Chizimuzo Okoli, Mary Kay Rayens

Biostatistics Faculty Publications

Objective:(1) Evaluate differences in demographic distributions between those with autism alone and those with autism concomitant with anxiety and (2) assess demographic factors associated with receipt of psychological therapy in patients with autism.Methods:Using deidentified health care claims data, we extracted all encounters among children with the International Classification of Diseases-10-CM for Autism Spectrum Disorder (F84) and flagged those with concomitant anxiety (F41.9). Extracted data included age, sex, race, ethnicity, insurance status, and Rural-Urban Continuum Codes. Current procedural terminology codes for psychological services were extracted. Data were analyzed using Mann-Whitney U tests, χ² tests of association, and logistic regression.Results:Demographic differences …

Leveraging Machine Learning Models To Explore Disparities In Prostate Cancer Diagnosis, Treatment, And Survival, Reuben Adatorwovor, Rasaq Oladapo, Parisa Ghasemi, Gaurav Kumar, Daniel J. Morton, Motolani E. Ogunsanya, Olufunmilola Abraham

Biostatistics Faculty Publications

Introduction: Prostate cancer (CaP) is the second most common cancer in men globally and a leading cause of cancer-related mortality, particularly among older men. In the United States, disparities in incidence, stage at diagnosis, and outcomes persist across racial, socioeconomic, and geographic lines. Men in medically underserved regions like Appalachia experience higher mortality due to limited access to timely screening and treatment. Given the complex interplay of clinical, behavioral, and sociodemographic factors, machine learning (ML) offers promise in identifying survival predictors that traditional models may overlook. This study applies ML models to assess the impact of age at diagnosis, treatment …

Outcomes Of A Pilot Randomized Clinical Trial Testing Brief Interventions To Increase Hiv Pre-Exposure Prophylaxis Uptake Among Rural People Who Inject Drugs Attending Syringe Services Programs, Hilary L. Surratt, Sarah Brown, Abby L. Burton, Will Cranford, Laura C. Fanucchi, Christie Green, Stephanie M. Mersch, Rebecca Rains, Philip M. Westgate

Biostatistics Faculty Publications

Background: Kentucky is one of seven states with high, sustained rural HIV transmission tied to injection drug use. Expanding access to pre-exposure prophylaxis (PrEP) has been endorsed as a key HIV prevention strategy; however, uptake among people who inject drugs (PWID) has been negligible in rural areas. Syringe services programs (SSPs) have been implemented throughout Kentucky’s Appalachian region, providing an important opportunity to integrate PrEP services. Objectives: The primary objective was to examine preliminary efficacy and effect sizes of the study interventions on PrEP initiation among HIV-negative PWID. Design: Parallel group randomized controlled trial. Methods: Eighty participants were enrolled from …

Clinical Criteria For Limbic-Predominant Age-Related Tdp-43 Encephalopathy, David A. Wolk, Peter T. Nelson, Liana Apostolova, Konstantinos Arfanakis, Patricia A. Boyle, Cynthia M. Carlsson, Nick Corriveau-Lecavalier, Penny Dacks, Bradford C. Dickerson, Kimiko Domoto-Reilly, Brittany N. Dugger, Rebecca Edelmayer, David W. Fardo, Michel J. Grothe, Timothy J. Hohman, David J. Irwin, Gregory A. Jicha, David T. Jones, Claudia H. Kawas, Edward B. Lee, Karen Lincoln, Gladys E. Maestre, Elizabeth C. Mormino, Chiadi U. Onyike, Ronald C. Petersen, Gil D. Rabinovici, Rosa Rademakers, Rema Raman

Biostatistics Faculty Publications

Limbic predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-NC) is highly prevalent in late life and a common co-pathology with Alzheimer's disease neuropathologic change (ADNC). LATE-NC is a slowly progressive, amnestic clinical syndrome. Alternatively, when present with ADNC, LATE-NC is associated with a more rapid course. With the emergence of anti-amyloid therapeutics, discrimination of LATE-NC from ADNC is critical and will lead to greater clinical recognition of amnestic patients without ADNC. Furthermore, co-pathology with LATE-NC may influence outcomes of these therapeutics. Thus there is a need to identify patients during life with likely LATE-NC. We propose criteria for clinical diagnosis of …

Code Status Discussions, Hunter Bechtold, Reagan T. Smith, Peter Wallenhorst, Kaylee Gouge, Sarah Schaefer, Kelsey Karnik, Kristen Mcquerry, Kristen E. Fletcher

Biostatistics Faculty Publications

Introduction: Residents frequently conduct code status discussions (CSDs) with patients, but many report not receiving formal training in this skill. While institutions have attempted to address this, there remains a need for a curriculum that uses standardized patients (SPs), is generalizable to students interested in different medical specialties, and has been tested on a large sample of students. Methods: We trained 192 fourth-year medical students across four different campuses in how to conduct CSDs during one 2-hour workshop as part of their Transition to Residency course in April 2024. Students worked with SPs as part of this workshop. Students at …

How Patient, Infection, And Cysticercus Characteristics Impact The Evolution Of Taenia Solium Larva In The Human Brain, Hongbin Zhang, Meghana G. Shamsunder, Pryanka Bawa, Arturo Carpio, W. Allen Hauser, Karina Quinde-Herrera, Alex Jaramillo, Elizabeth A. Kelvin

Biostatistics Faculty Publications

Neurocysticercosis is a poorly understood infection of the central nervous system with Taenia solium larva and treatment often fails to kill all the parasitic larva. Most research on this infection has used patient-level data, looking at summaries of the encysted parasitic cysticercus burden. Cyst-level analysis is needed to identify factors that impact individual cyst trajectories and how that may vary based on characteristics of the patient, infection, and cyst being followed. We disaggregated data on 221 cysts from 117 patients who participated in a trial evaluating the impact of albendazole treatment to identify factors that impact cyst evolution over time …

A Myostatin Inhibitory Antibody Combined With Insulin, Partially Rescues The Musculoskeletal Phenotype Of Female Insulin-Deficient Diabetic Mice, R. Clay Bunn, Reuben Adatorwovor, Philip D. Ray, Alexander R. Keeble, Christopher S. Fry, Sasidhar Uppuganti, Jeffry S. Nyman, John L. Fowlkes, Evangelia Kalaitzoglou

Biostatistics Faculty Publications

Introduction: Type 1 diabetes is associated with deficits in both skeletal muscle and bone. Inhibition of myostatin, a negative regulator of muscle mass, was explored as a druggable target to improve the musculoskeletal phenotype associated with insulin-deficient diabetes in female mice. Methods: We investigated whether administration of an inhibitory myostatin antibody (MyoAb) in streptozotocin-induced diabetes in female mice is protective for skeletal muscle and bone. DBA/2J female mice were injected with low-dose streptozotocin or with citrate buffer (vehicle). Subsequently, mice were implanted with insulin-containing or vehicle pellets, with groups being randomized to myostatin or control antibody for 8 weeks. At …

Diagnosing Statistical Education Needs Of Health Science Learners, Amy S. Nowacki, Ann M. Brearley, Robert A. Oster, Emily Slade, Katrina L. Devick, Matthew J. Hayat, Sally W. Thurston

Biostatistics Faculty Publications

Many types of health science learners, including clinical and translational scientists, students, researchers, and clinicians, seek to increase their knowledge of biostatistics. These learners are heterogeneous in their field, career stage and career focus. Based on the collective experience of an expert panel with over 115 years teaching statistics to health science learners, we propose a framework for considering the needs of health science learners motivated by their career goals. This framework defines four types of health science learners seeking statistical training: (a) consumers, (b) “milestone makers”, (c) biomedical researchers with statistical support, and (d) biomedical researchers without statistical support. …