Digital Commons Network^™

Surgical Outcomes And Associated Morbidity Of Active And Expectant Management Of Second-Trimester Placenta Accreta Spectrum (Pas), Jessian L Munoz, Rachel Counts, Amanda E Lacue, Kayla E Ireland, Patrick S Ramsey, Kristyn Brandi

Faculty, Staff and Students Publications

Background and Objectives: Management of second-trimester placenta accreta spectrum (PAS) is currently center-dependent with minimal evidence-based practices. This study aims to analyze outcomes of hysterectomy as second-trimester active management (AM) versus cesarean hysterectomy as expectant management (EM) in cases of PAS with intraoperative and postoperative outcomes. Materials and Methods: This study is a retrospective case-control study of patients with a pathology-confirmed diagnosis of PAS managed at a single center over 16 years (2005–2020). All cases were diagnosed during the first or second trimester by ultrasonography and managed by the same multidisciplinary team with delivery within the second trimester. Results: …

Animal Models Of Non-Respiratory, Post-Acute Sequelae Of Covid-19, Abigail Vanderheiden, Michael S Diamond

2020-Current year OA Pubs

Post-acute sequelae of COVID-19 (PASC) are a diverse set of symptoms and syndromes driven by dysfunction of multiple organ systems that can persist for years and negatively impact the quality of life for millions of individuals. We currently lack specific therapeutics for patients with PASC, due in part to an incomplete understanding of its pathogenesis, especially for non-pulmonary sequelae. Here, we discuss three animal models that have been utilized to investigate PASC: non-human primates (NHPs), hamsters, and mice. We focus on neurological, gastrointestinal, and cardiovascular PASC and highlight advances in mechanistic insight that have been made using these animal models, …

Engaging Dystonia Networks With Subthalamic Stimulation, Konstantin Butenko, Evan M Gordon, Nico U F Dosenbach, Et Al.

2020-Current year OA Pubs

Deep brain stimulation is an efficacious treatment for dystonia. While the internal pallidum serves as the primary target, recently, stimulation of the subthalamic nucleus (STN) has been investigated. However, optimal targeting within this structure and its surroundings have not been studied in depth. Indeed, historical targets that have been used for surgical treatment of dystonia are directly adjacent to the STN. Further, multiple types of dystonia exist, and outcomes are variable, suggesting that not all types would profit maximally from the same target. Therefore, a thorough investigation of neural substrates underlying stimulation effects on dystonia signs and symptoms is warranted. …

Tolerability And Long-Term Disease Control By Ighv Mutation Status Among Patients With Cll On Ibrutinib Arm Of E1912, Tait D Shanafelt, Amanda F Cashen, Et Al.

2020-Current year OA Pubs

No abstract provided.

Sialylated Igg Induces The Transcription Factor Rest In Alveolar Macrophages To Protect Against Lung Inflammation And Severe Influenza Disease, Saborni Chakraborty, Derek E Byers, Philip A Mudd, Michael S Diamond, Et Al.

2020-Current year OA Pubs

While most respiratory viral infections resolve with little harm to the host, severe symptoms arise when infection triggers an aberrant inflammatory response that damages lung tissue. Host regulators of virally induced lung inflammation have not been well defined. Here, we show that enrichment for sialylated, but not asialylated immunoglobulin G (IgG), predicted mild influenza disease in humans and was broadly protective against heterologous influenza viruses in a murine challenge model. Mechanistic studies show that sialylated IgG mediated this protection by inducing the transcription factor repressor element-1 silencing transcription factor (REST), which repressed nuclear factor κB (NF-κB)-driven responses, preventing severe lung …

Identifying The Effect Of Architecture Morphology On Wind Fields And Pm2.5 Dispersion At The Urban Block Scale Via A Combined Scheme, Bin Guo, Lu Li, Xiaowei Zhu, Zheng Wang, Miaoyi Chen, Lin Pei, Tengyue Guo

Mechanical and Materials Engineering Faculty Publications and Presentations

This study explores the potential of architecture morphology to mitigate PM2.5 pollution through enhanced urban ventilation. Despite the recognized influence of building designs on wind and air pollution distribution at the urban block scale, specific mechanisms remain poorly understood. To address this gap, we have developed an integrative approach combining in-situ observations, Geographic Information System (GIS), Remote Sensing (RS), Computational Fluid Dynamics (CFD), and statistical modeling. Here, CFD simulates the flow field and PM2.5 dispersion, using in-situ observations for turbulence model selection. GIS quantify architecture morphology parameters to establish accurate CFD boundary conditions, ensuring simulations reflect real-world conditions and precise …

Butte Reduction Works (Brw) Phase Ii Interim Demolition Plan Construction Drawings And Floodplain Encroachment Analysis, Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Spatial Distribution Of Tumor Cells In Clear Cell Renal Cell Carcinoma Is Associated With Metastasis And A Matrisome Gene Expression Signature, Prahlad Bhat, Pheroze Tamboli, Kanishka Sircar, Kasthuri Kannan

Faculty, Staff and Student Publications

Background/Objectives: Predicting the behavior of clear cell renal cell carcinoma (ccRCC) is challenging using standard-of-care histopathologic examination. Indeed, pathologic RCC tumor grading, based on nuclear morphology, performs poorly in predicting outcomes of patients with International Society of Urological Pathology/World Health Organization grade 2 and 3 tumors, which account for most ccRCCs.

Methods: We applied spatial point process modeling of H&E-stained images of patients with grade 2 and grade 3 ccRCCs (n = 72) to find optimum separation into two groups.

Results: One group was associated with greater spatial randomness and clinical metastasis (p < 0.01). Notably, spatial analysis outperformed standard pathologic grading in predicting clinical metastasis. Moreover, cell-to-cell interaction distances in the metastasis-associated group were significantly greater than those in the other patient group and were also greater than expected by the random distribution of cells. Differential gene expression between the two spatially defined groups of patients revealed a matrisome signature, consistent with the extracellular matrix's crucial role in tumor invasion. The top differentially expressed genes (with a fold change > 3) stratified a larger, multi-institutional …

Anti-Ctla-4 Generates Greater Memory Response Than Anti-Pd-1 Via Tcf-1, Stephen Mok, Huey Liu, Didem Ağaç Çobanoğlu, Nana-Ama A S Anang, James J Mancuso, E John Wherry, James P Allison

Faculty, Staff and Student Publications

The effects of T cell differentiation arising from immune checkpoint inhibition targeting cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and programmed cell death protein 1 (PD-1) on the immunological memory response remain unclear. Our investigation into the effects of anti-CTLA-4 and anti-PD-1 on memory T cell formation in mice reveals that memory T cells generated by anti-CTLA-4 exhibit greater expansion, cytokine production, and antitumor activity than those from anti-PD-1. Notably, anti-CTLA-4 preserves more T cell factor-1 (TCF-1)+ T cells during priming, while anti-PD-1 leads to more thymocyte selection-associated high mobility group box (TOX)+ T cells. Experiments using conditional

Cardiometabolic Multimorbidity And Dementia Onset Among Middle-Aged And Older Adults: Differences By Race/Ethnicity., Siting Chen, Ana R. Quiñones, Corey L. Nagel, Nicholas J. Bishop, Heather G. Allore, Jason T. Newsom, Jeffrey Kaye, Anda Botoseneanu

Psychology Faculty Publications and Presentations

Racial/ethnic minoritized groups in the U.S. have higher prevalence of cardiometabolic multimorbidity and experience higher risk of dementia. This study evaluates the relationship between cardiometabolic multimorbidity and dementia onset according to racial/ethnic group in a nationally representative cohort of U.S. middle-aged and older adults.

A Proposed Mhealth Intervention To Address Patient Barriers To Colposcopy Attendance: Qualitative Interview Study Of Clinic Staff And Patient Perspectives, Jennifer Hemler, Rachel Wagner, Brittany Sullivan, Myneka Macenat, Erin Tagai, Jazmarie Vega, Enrique Hernandez, Suzanne Miller, Kuang-Yi Wen, Charletta Ayers, Mark Einstein, Shawna Hudson, Racquel Kohler

Department of Medical Oncology Faculty Papers

BACKGROUND: Cervical cancer disparities persist among minoritized women due to infrequent screening and poor follow-up. Structural and psychosocial barriers to following up with colposcopy are problematic for minoritized women. Evidence-based interventions using patient navigation and tailored telephone counseling, including the Tailored Communication for Cervical Cancer Risk (TC3), have modestly improved colposcopy attendance. However, the efficacious TC3 intervention is human resource-intense and could have greater reach if adapted for mobile health, which increases convenience and access to health information.

OBJECTIVE: This study aimed to describe feedback from clinic staff members involved in colposcopy processes and patients referred for colposcopy regarding adaptions …

Helminth Infections Affect Host Immune Responses To Viral Infections And Vaccines, Juan García-Bernalt Diego, Pritesh Desai, Stephen T Yeung, Payal Damani-Yokota, Kamal M Khanna, Michael S Diamond, Michael Schotsaert

2020-Current year OA Pubs

Helminths are highly prevalent in many regions of the world. Due to the chronic nature of most helminth infections, these parasites are proficient immunomodulators of their hosts. This modulation often leads to skewed or even impaired immune responses against unrelated antigens, such as viruses and vaccines, which can be both beneficial and detrimental for the host. The extent of these effects and the impact on the outcomes of viral infection depends on a variety of factors including timing and tropism of both infections, pathological mechanisms, genetic background, and environmental factors. In this review, we dissect these complex interactions between virus …

Analysis Of Smart Governance In Tax Digitalization In Bandung City (A Case Study Of E-Satria Application), Regina Fauzia Adisa, Sri Mulyani

Journal of Accounting Auditing and Business

This study aims to analyze the implementation of the e-Satria application in achieving smart governance in the city of Bandung. The analysis includes community participation, transparency, and quality of service as evaluated through effectiveness, efficiency, time savings, and data security. This study employs a qualitative approach. The validation of research data utilizes data triangulation, where information is gathered from various informants, documents, and an analysis of the e-satria application. The informants for this study included representatives from the Regional Revenue Management Agency (BPPD), the Bandung City Inspectorate, and De.U Coffee, a restaurant in the Bandung area that uses the application. …

Analyzing Tiktok’S Influence On Youth Political Activism And Social Participation In Malaysia, Nor Azyani Tsania Mohd Nor, Syahirah Samantha Foo Su Sien Mohd Fird, Nur Marissa Nabilah Mohd Ridhwan, Mohamad Hafifi Jamri

Jurnal Wacana Politik

Despite TikTok’s popularity among young users, concerns persist regarding their lack of political awareness and gullibility. This research aims to address this gap by examining TikTok usage patterns among Malaysian youth and analyzing user interactions with political and social content. The research participants consisted of youths aged 18 to 29 years old in Malaysia. Employing a quantitative research design, the study used surveys to gather data and descriptive statistical analysis. The collected data was analyzed using the SPSS software. The study’s findings indicate TikTok’s potential for political usage and respondents show a moderately high agreement on TikTok as a platform …

Political Polarization In The 2024 Local Elections: An Analysis Of Its Impact And Implications For Local Democracy In Indonesia, Muhtar Muhtar, Budi Setiyono, Fitriyah Fitriyah, Nur Hidayat Sardini

Jurnal Wacana Politik

Regional head elections (Pilkada) are a crucial moment in Indonesia’s political dynamics, but in 2024, political polarization reached its peak, causing significant impacts on local democracy. This study aims to investigate the phenomenon of political polarization in the 2024 regional elections and analyze its implications for the sustainability of local democracy in Indonesia. Through a mixed approach that combines qualitative and quantitative analysis, this study attempts to understand the root causes of political polarization, measure the level of polarization in different regions, and evaluate the resulting political consequences. Political polarization in the context of the 2024 regional elections reflects the …

Youth Mobilization In The 2019 Election Campaign In West Java, Indonesia (Study Of The Gerindra Party, The Indonesia Democratic Party Of Struggle, And The Prosperous Justice Party), Siti Witianti, Caroline Paskarina, Ratnia Solihah

Jurnal Wacana Politik

West Java has the largest number of voters including young elections, but there are symptoms where political parties have rarely been placed as subjects in elections by political parties. This study aims to describe the strategies of the Gerindra Party, PDIP, and PKS in mobilizing youth support in the 2019 elections in West Java and to analyze research phenomena based on the theory used so that it is hoped that new concepts will be obtained in mobilizing youth support during the election momentum, especially in implementing strategies mobilization that places the youth segment as a political subject, not only as …

An Evaluation Of A Community Dementia Screening Program In Rural Kenya: Dem-Sky, Nicolas Farina, Christine W. Musyimi, Kevin Onuonga, David M. Ndetei

Peninsula Medical School

INTRODUCTION: This study describes the implementation outcomes and evaluation of DEM-SKY, a community-based dementia screening program developed in rural Kenya with the support of community health care workers (CHWs). METHODS: DEM-SKY was delivered to 3546 older adults in Makueni County, Kenya, over a 6-month period. Using a mixed-methods design, we explored implementation outcomes with stakeholders through surveys and interviews. RESULTS: The program demonstrated good acceptability, adoption, and fidelity and was effective in instigating behavior change. Individuals who screened positive for dementia were 28.7 times more likely to intend to speak to a doctor. Qualitative data showed that participants valued the …

A Pilot And Feasibility Study Investigating The Abundance And Activity Of Nitrate-Reducing Bacteria In Women With Pre-Eclampsia, Lisa Du Toit, Ifeoma Offiah, Alvaro Redondo-Rio, Tanya Kahawita, Michele Kiernan, Yen Ming Lin, Louise A. Belfield, Gemma Montagut, Alicia Benavente, Tomas Nicholas, Amazon Doble, Renske Dikkers, Robert Freeman, Toni Gabaldón, Zoe Brookes, Raul Bescos Garcia

Peninsula Dental School

BackgroundOral health may influence blood pressure control by modulating the abundance and activity of nitrate-reducing bacteria, which are essential for enhancing nitrite and nitric oxide (NO) bioavailability. This study aimed to investigate the oral health and microbiome composition of women with pre-eclampsia (PET) compared to healthy controls (CN).MethodsTen PET and eleven CN women participated in this study, respectively. An oral health examination was conducted in all the participants. Saliva and blood samples were collected for analysis of the oral microbiome and NO biomarkers.ResultsHigher plaque levels were observed in the PET group compared to the CN group (P = 0.038). The …

The Role Of Social Communication In The Social Cohesion Of Athletic Team Players In The Ministry Of Education, Rawaah Sukkarieh

Jordan Journal of Applied Science-Humanities Series

The study aimed to identify the role of social communication in social cohesion among athletic players in the Ministry of Education. A descriptive approach was used, employing a questionnaire consisting of 15 items distributed across three areas: 'belonging to the group,' 'satisfying social needs,' and 'integration into teamwork.' The sample consisted of 115 players from the teams of the educational directorates in the Ministry of Education. Statistical methods used included averages, standard deviations, Pearson's correlation coefficient, Cronbach's alpha coefficient, and the T-test. The most important results indicated that the role of social communication in social cohesion among athletic team players …

After Development Journalism: Asia And Africa, Muhammad Izawan Baharin, Moniza Waheed, Lea Hellmueller, Robert A. White, Aayush Soni

Communication Research Trends

No abstract provided.

Grief And Bereavement In Young Adult College Students: A Review Of The Literature And Implications For Practice And Research, Chan L. Thai, Julia F. Moore

Communication Research Trends

No abstract provided.

Unbeatable? Debates And Divides In Gender And Video Game Research, Carolyn Cunningham

Communication Research Trends

No abstract provided.

Nonverbal Communication, Paul A. Soukup S.J.

Communication Research Trends

No abstract provided.

Reshaping Resilience Mental Health Challenges In Post-Pandemic Students And Workforce Readiness, Ryan Potts, Tarandeep Kaur Arora, Susan Miller, Julia Ann Boyd Dr.

Posters-at-the-Capitol

The COVID-19 pandemic had a significant impact on mental health, especially on college students, who faced disruptions to their education and social environments. This study explores the mental health effects of the pandemic on students at Murray State University, focusing on changes in anxiety, depression, relationships, and academic performance. Using survey data collected from students in Occupational Safety and Health (OSH) and the Nursing Program, the study aims to understand the trends across pre-pandemic, during-pandemic, and post-pandemic periods. The findings show a significant increase in anxiety and depression during the pandemic, with effects lasting post-pandemic, alongside differences in how students …

A Call For Increased Support For Spanish-Speaking Workforce, Clients And Caretakers In Applied Behavior Analysis (Aba), Michele Curd, Becky Nastally

Posters-at-the-Capitol

The Ethics Code for Behavior Analysts (Behavior Analyst Certification Board, 2020) requires all professionals certified in ABA service delivery to provide services in a manner that supports client rights and the diversity of the client population. As the Hispanic/Latinx and Spanish-speaking client population increases in the United States over time, an increased need for culturally competent professionals in the field of mental health care is made apparent. Though there are professionals delivering multilingual and culturally competent services, it is unknown how many Spanish-speaking behavior analysts practice in the United States as the BACB does not currently collect data regarding certificant …

Parasocial Interactions And Relationships With Media Characters–An Inventory Of 60 Years Of Research, Nicole Liebers, Holger Schramm

Communication Research Trends

No abstract provided.

Communication And Leadership 2020: Intersectional, Mindful, Digital, Carolyn M. Cunningham, Michael Hazel, Tracey J. Hayes

Communication Research Trends

No abstract provided.

Woman Suffrage And Communication, Paul A. Soukup S.J.

Communication Research Trends

No abstract provided.

The Measurement Of Trust In Communication Research Part 1, Paola Pascual-Ferrá

Communication Research Trends

No abstract provided.

Noda News January 2025

New Orleans Dental Association News

New Orleans Dental Association (NODA) News includes regular columns with regional news impacting the New Orleans membership including: columns from the President and Executive Director, feature articles relating to the field of dentistry, association events and upcoming activities, component news, continuing education opportunities, and classifieds.