Digital Commons Network^™

Nourishing Change In Houston, Texas: Exploring Grocery Shopping Behaviours And Fruit And Vegetable Consumption Among Low-Income Families In The Brighter Bites Program, Victoria Kwentua, Allison Marshall, Ru-Jye Chuang, Jessica Chen, Christine Markham, Mallika Mathur, Mike Pomeroy, Megan Hall, Shreela Sharma

Faculty, Staff and Student Publications

OBJECTIVE: We qualitatively examine the grocery shopping behaviours and fruit and vegetable consumption of low-income families participating in the Brighter Bites program in Houston, Texas.

DESIGN: We used a single-group observational study design. We used (1) purposive sampling of schools and (2) convenience sampling of parents/caregivers to recruit participants. Research staff conducted three face-to-face qualitative focus groups in Spanish and English. Transcripts were coded using deductive and inductive reasoning.

SETTING: Three elementary schools serving low-income families in Houston, Texas, in February-May of 2022.

PARTICIPANTS: Brighter Bites parents/caregivers from the 2021-2022 school year.

RESULTS: Three primary themes emerged: (1) child involvement …

Executive Summary: Clinical Practice Guideline Medication Reconciliation As A Catalyst For Patient Safety And Outcome, Monica Arevalo

Walden Dissertations and Doctoral Studies

This doctoral project centered on the development and implementation of a Clinical Practice Guideline (CPG) aimed at improving the accuracy of medication reconciliation for patients with complex medication regimens. Medication discrepancies and associated adverse drug events are significant concerns in healthcare, particularly during care transitions. The project addressed the practice-focused question: Will an interprofessional team reach consensus on a plan to standardize and automate the medication reconciliation process? This question highlights the importance of interprofessional collaboration in ensuring patient safety and improving healthcare outcomes. The project’s purpose was to standardize and automate the reconciliation process to reduce discrepancies, improve medication …

Familial Income Status, Food Insecurity, And Oral Health In Adolescents In The Prepandemic Era, Gersom I. Jimeenz

Walden Dissertations and Doctoral Studies

Oral health and hygiene present a significant public health problem that can cause short- and long-term effects among families with adolescents. This quantitative, correlational research design study aimed to investigate associations between food security (FS) levels and familial income status to oral health and hygiene among adolescents aged 13-19 throughout the United States. This study used the health belief model to determine if the perceived susceptibilities, severities, benefits, and barriers can lead to self-efficacy and cues to action among adolescents who experience varying familial income levels. Controlled variables included age, sex, and race. Data were derived from the National Health …

Elementary Teachers’ Experiences Supporting The Academic Growth And Development Of Students On The Autism Spectrum In Inclusion Classrooms, Erica Williams Harryman

Walden Dissertations and Doctoral Studies

The problem addressed in this study is that elementary inclusion teachers in urban school districts in a northeastern state in the United States struggle to support the academic growth and development of their students with autism spectrum disorder (ASD). The purpose of this study was to explore the experiences of these teachers and identify the institutional conditions they perceive as necessary to foster positive academic outcomes for students with ASD, informing the study's two research questions. Framed by Bandura’s social cognitive theory, particularly its principle of triadic reciprocality, the study employed a basic qualitative design. Twelve elementary inclusion teachers participated …

Relationship Between Racial Trauma, Microaggression, Cultural Coping Behaviors, And Resilience Among Black Counseling Students, Chrismathe Lindsay

Walden Dissertations and Doctoral Studies

Black students in counseling programs face many challenges stemming from racial trauma and microaggression; for instance, they are at greater risk for mental health problems and degree incompletion. Grounded in critical race theory, the purpose of this quantitative correlation study was to examine whether racial trauma, the experience of microaggression, and cultural coping behaviors were significant predictors of resilience and whether cultural coping behaviors mediated the relationship between racial trauma, microaggression, and resilience among Black counseling students. A convenience sample was used to anonymously survey 80 Black counseling students. The results of the multiple regression mediation analysis showed a statistically …

Clinical Practice Guideline For Lifestyle Management Of Clients On Second Generation Antipsychotic Medications, Althea G. Andrade

Walden Dissertations and Doctoral Studies

Second-generation antipsychotics (SGAs) are a category of medications principally employed for the treatment of certain mental illnesses. One major downside of the medications is their tendency to induce weight gain, which can result in negative metabolic consequences and raise the likelihood of cardiovascular disease. The clinic setting was focused on the mental health component for the patients on SGAs, and there was little time and ability to address physical health needs, such as weight gain, nutrition, and exercise, which led to comorbidities and possible exacerbation of the mental health issues. Therefore, the purpose of this doctor of nursing practice (DNP) …

Saying Hello Again Rather Than A Long Goodbye: A Novel Way Of Addressing Pre-Death Grief And Facilitating Continuing Bonds For Dementia Caregivers, Elizabeth Gilmour, Edith Steffen

School of Psychology

The ‘Hello Again’ letter-writing intervention is sometimes used in grief counselling to facilitate continuing bonds with the deceased. Family member caregivers of those with dementia often experience a ‘long goodbye’, as the relationship with their loved one gradually changes through serial losses before they have physically died, making the relationship markedly different than the one before the dementia. There are limited interventions to support caregivers with this pre-death grief. This study aimed to address this lack by offering the ‘Hello Again’ intervention to dementia family caregivers, exploring the perceived helpfulness of the task, and attempting to understand the meanings of …

Landworks Evaluation 1 April 2023-31 March 2024: A 'Desistance-Supporting' Community Which Offers 'Living Proof Of Active Hope', Patricia Gray, Julie Parsons

School of Law, Humanities and Social Sciences

This year marked the 10th anniversary of LandWorks, which was established in 2013 and became an independent charity in 2016. The ‘Annual Supporters Day’, which was held on the 14th July, was used to celebrate this milestone anniversary and 275 supporters, volunteers and partners attended. LandWorks produced a new book to commemorate the occasion, and a copy of this book can be found here: 10 Years of Land Works in 10 Numbers (https://www.landworks.org.uk/wp-content/uploads/2023/05/10-years-of-LandWorks-in-10-numbers.pdf).

Doing Doctorates Differently: The Parapedagogic Potentialities Of The Phd Process, Helen Bowstead, Ken Gale, Mary Catherine Garland, Claire Walsh

School of Law, Humanities and Social Sciences

Coming together in this conference collectivity, these are doctorates that in their doing – thinking, researching, writing, supervising, assessing, publishing – live by “no preexisting rules, processes, methods, categories or ‘determining judgement’.”1 They are doctorates that “cannot be taught or learned.”23 Such PhDs – thesis’ refusing to (con)form – in their ever probing, in-forming, stubborn curiousness of problematics living beyond solution driven research, lead to transformative moments in the act of learning, that in their difference are “...made sense of, not in terms of what [they] mean but in terms of what [they] do.”4Yet in their difference, doctorates working within …

Risk-Stratified Venous Thromboembolism Chemoprophylaxis After Total Joint Arthroplasty: Evaluation Of An Institutional Approach., Sara J Hyland, Maria J Fada, Michelle Secic, Robert A Fada, Marie M Lockhart, Richard H Parrish

OhioHealth Research Institute Articles

No abstract provided.

The Impact Of Fibular Fixation Method On Pilon Fracture Healing., Anthony Perugini, Scott Hyland, James Iandoli, Zachary Hill, John Peabody, Daniel Degenova, Mallory Faherty, Benjamin Taylor

OhioHealth Research Institute Articles

No abstract provided.

Cancer-Related Health Behaviors During The Covid 19 Pandemic In Geographically Diverse Samples Across The Us, Breanna B Greteman, Bettina F Drake, Kia L Davis, Et Al.

2020-Current year OA Pubs

BACKGROUND: The COVID-19 pandemic involved business closures (e.g., gyms), social distancing policies, and prolonged stressful situations that may have impacted engagement in health behaviors. Our study assessed changes in cancer-related health behaviors during the pandemic, specifically physical activity, fruit/vegetable intake, smoking/tobacco use, and alcohol consumption.

METHODS: Eight cancer centers administered mailed/web-based/telephone surveys between June 2020 and March 2021. Surveys assessed demographics, perceptions on social distancing, and self-reported changes of behaviors (less/same/more) associated with cancer prevention or risk, e.g., physical activity, fruit/vegetable intake, tobacco/smoking use, and alcohol consumption. Descriptive analyses and logistic regression models assessed association of variables with behavior change. …

Re: December 2024 Berkeley Pit Migratory Waterfowl Protection Monthly Report, Mark Thompson, Loren Burmeister

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Alleviation Of Liver Fibrosis By Inhibiting A Non-Canonical Atf4-Regulated Enhancer Program In Hepatic Stellate Cells, Li-Xian Yang, Chuangye Qi, Si Lu, Xiang-Shi Ye, Parnaz Merikhian, Du-Yu Zhang, Tao Yao, Jiang-Sha Zhao, Ying Wu, Yongshi Jia, Bo Shan, Jinghai Chen, Xiaozhou Mou, Jia You, Wenbo Li, Yu-Xiong Feng

Faculty, Staff and Student Publications

Liver fibrosis is a critical liver disease that can progress to more severe manifestations, such as cirrhosis, yet no effective targeted therapies are available. Here, we identify that ATF4, a master transcription factor in ER stress response, promotes liver fibrosis by facilitating a stress response-independent epigenetic program in hepatic stellate cells (HSCs). Unlike its canonical role in regulating UPR genes during ER stress, ATF4 activates epithelial-mesenchymal transition (EMT) gene transcription under fibrogenic conditions. HSC-specific depletion of ATF4 suppresses liver fibrosis in vivo. Mechanistically, TGFβ resets ATF4 to orchestrate a unique enhancer program for the transcriptional activation of pro-fibrotic EMT genes. …

Functional Characterization Of Qt Interval Associated Scn5a Enhancer Variants Identify Combined Additive Effects, Lavanya Gunamalai, Parul Singh, Brian Berg, Leilei Shi, Ernesto Sanchez, Alexa Smith, Ghislain Breton, Mark T Bedford, Darius Balciunas, Ashish Kapoor

Faculty, Staff and Student Publications

Several empirical and theoretical studies suggest the presence of multiple enhancers per gene that collectively regulate gene expression, and that common sequence variation impacting on the activities of these enhancers is a major source of inter-individual gene expression variability. However, for the vast majority of genes, enhancers and the underlying regulatory variation remains unknown. Even for the genes with well-characterized enhancers, the nature of the combined effects from multiple enhancers and their variants, when known, on gene expression regulation remains unexplored. Here, we have evaluated the combined effects from five SCN5A enhancers and their regulatory variants that are known to …

A Phase Ia Study Of A Novel Anti-Her2 Antibody-Drug Conjugate Gq1001 In Patients With Previously Treated Her2 Positive Advanced Solid Tumors, Chenfei Zhou, Bin Wang, Christina Teng, Hui Yang, Sarina A Piha-Paul, Gary Richardson, Ashanya Malalasekera, Yajun Sun, Wei Wang, Jieqiong Liu, Yan Shi, Xianbao Zhan, Charlotte Lemech

Faculty, Staff and Student Publications

Background: A novel anti-human epidermal growth factor receptor 2 (HER2) antibody-drug conjugate (ADC) GQ1001 was assessed in patients with previously treated HER2 positive advanced solid tumors in a global multi-center phase Ia dose escalation trial.

Methods: In this phase Ia trial, a modified 3 + 3 study design was adopted during dose escalation phase. Eligible patients were enrolled, and GQ1001 monotherapy was administered intravenously every 3 weeks. The starting dose was 1.2 mg/kg, followed by 2.4, 3.6, 4.8, 6.0, 7.2 and 8.4 mg/kg. Extra patients were enrolled into 6.0, 7.2, and 8.4 mg/kg cohorts as dose expansion phase. The primary …

Lived Experiences Of Emerging Adults’ Transitioning Back To College Campus After Covid-19., Aleesha Hayes

Walden Dissertations and Doctoral Studies

The COVID-19 pandemic led to a worldwide shutdown as there were many uncertainties on how to prevent exposure. Emerging adults who were full time students were impacted in a variety of ways, both negatively and positively. There is substantial research on the impact that college students had when transitioning off college campuses. However, there is a lack of literature on the experiences that emerging adults had when transitioning back to college campus after COVID-19. This gap is important because multiple transitions have significant implications for development and well-being. To better understand this, a phenomenological qualitative study was conducted to explore …

Executive Summary: Clinical Practice Guideline Medication Reconciliation As A Catalyst For Patient Safety And Outcome, Monica Arevalo

Walden Dissertations and Doctoral Studies

This doctoral project centered on the development and implementation of a Clinical Practice Guideline (CPG) aimed at improving the accuracy of medication reconciliation for patients with complex medication regimens. Medication discrepancies and associated adverse drug events are significant concerns in healthcare, particularly during care transitions. The project addressed the practice-focused question: Will an interprofessional team reach consensus on a plan to standardize and automate the medication reconciliation process? This question highlights the importance of interprofessional collaboration in ensuring patient safety and improving healthcare outcomes. The project’s purpose was to standardize and automate the reconciliation process to reduce discrepancies, improve medication …

Elementary Teachers’ Experiences Supporting The Academic Growth And Development Of Students On The Autism Spectrum In Inclusion Classrooms, Erica Williams Harryman

Walden Dissertations and Doctoral Studies

The problem addressed in this study is that elementary inclusion teachers in urban school districts in a northeastern state in the United States struggle to support the academic growth and development of their students with autism spectrum disorder (ASD). The purpose of this study was to explore the experiences of these teachers and identify the institutional conditions they perceive as necessary to foster positive academic outcomes for students with ASD, informing the study's two research questions. Framed by Bandura’s social cognitive theory, particularly its principle of triadic reciprocality, the study employed a basic qualitative design. Twelve elementary inclusion teachers participated …

Familial Income Status, Food Insecurity, And Oral Health In Adolescents In The Prepandemic Era, Gersom I. Jimeenz

Walden Dissertations and Doctoral Studies

Oral health and hygiene present a significant public health problem that can cause short- and long-term effects among families with adolescents. This quantitative, correlational research design study aimed to investigate associations between food security (FS) levels and familial income status to oral health and hygiene among adolescents aged 13-19 throughout the United States. This study used the health belief model to determine if the perceived susceptibilities, severities, benefits, and barriers can lead to self-efficacy and cues to action among adolescents who experience varying familial income levels. Controlled variables included age, sex, and race. Data were derived from the National Health …

Geospatial Analysis Of Social Variables Of The Health Opportunity Index And Stroke Prevalence In Health And Human Services Region 3, Wanderimam R. Tuktur

Walden Dissertations and Doctoral Studies

Disparities exist in stroke prevalence and outcome. There is sparsity of ecological studies at the census tract level that elucidate neighborhood predictors of stroke prevalence in states across U.S. Health and Human Services Region 3 (HHS Region 3: Delaware, Maryland, Pennsylvania, Virginia, West Virginia, and the District of Columbia). This study was conducted to explore the geospatial relationship between the 13 indicators of the Health Opportunity Index (HOI) and stroke prevalence at the census tract level in HHS Region 3 using four HOI indicator profiles: (a) neighborhood and built environment profile, (b) social and community context profile, (c) resource profile, …

Relationship Between Racial Trauma, Microaggression, Cultural Coping Behaviors, And Resilience Among Black Counseling Students, Chrismathe Lindsay

Walden Dissertations and Doctoral Studies

Black students in counseling programs face many challenges stemming from racial trauma and microaggression; for instance, they are at greater risk for mental health problems and degree incompletion. Grounded in critical race theory, the purpose of this quantitative correlation study was to examine whether racial trauma, the experience of microaggression, and cultural coping behaviors were significant predictors of resilience and whether cultural coping behaviors mediated the relationship between racial trauma, microaggression, and resilience among Black counseling students. A convenience sample was used to anonymously survey 80 Black counseling students. The results of the multiple regression mediation analysis showed a statistically …

Clinical Practice Guideline For Lifestyle Management Of Clients On Second Generation Antipsychotic Medications, Althea G. Andrade

Walden Dissertations and Doctoral Studies

Second-generation antipsychotics (SGAs) are a category of medications principally employed for the treatment of certain mental illnesses. One major downside of the medications is their tendency to induce weight gain, which can result in negative metabolic consequences and raise the likelihood of cardiovascular disease. The clinic setting was focused on the mental health component for the patients on SGAs, and there was little time and ability to address physical health needs, such as weight gain, nutrition, and exercise, which led to comorbidities and possible exacerbation of the mental health issues. Therefore, the purpose of this doctor of nursing practice (DNP) …

Lived Experiences Of Emerging Adults’ Transitioning Back To College Campus After Covid-19., Aleesha Hayes

Walden Dissertations and Doctoral Studies

The COVID-19 pandemic led to a worldwide shutdown as there were many uncertainties on how to prevent exposure. Emerging adults who were full time students were impacted in a variety of ways, both negatively and positively. There is substantial research on the impact that college students had when transitioning off college campuses. However, there is a lack of literature on the experiences that emerging adults had when transitioning back to college campus after COVID-19. This gap is important because multiple transitions have significant implications for development and well-being. To better understand this, a phenomenological qualitative study was conducted to explore …

Neoadjuvant Or Concurrent Atezolizumab With Chemoradiation For Locally Advanced Cervical Cancer: A Randomized Phase I Trial, Jyoti Mayadev, Dmitriy Zamarin, Wei Deng, Heather A. Lankes, Giulio Pesci, Hayeon Kim, Junzo P. Chino, Barbara Banbury, Ned Sherry, Elad Sharon, Sharad A. Ghamande, Catherine Ferguson, Loren Mell, Laura Holman, Cara Mathews, David O'Malley, Alexander Olawaiye, Elizabeth Hopp, Charles Leath, Larry Copeland, Robert Mannel, Roisin O'Cearbhaill, Carol Aghajanian, Russell J. Schilder

Department of Medical Oncology Faculty Papers

Combined immune checkpoint blockade (ICB) and chemoradiation (CRT) is approved in patients with locally advanced cervical cancer (LACC) but optimal sequencing of CRT and ICB is unknown. NRG-GY017 (NCT03738228) was a randomized phase I trial of atezolizumab (anti-PD-L1) neoadjuvant and concurrent with CRT (Arm A) vs. concurrent with CRT (Arm B) in patients with high-risk node-positive LACC. The primary endpoint was the fraction of expanded tumor-associated T-cell receptor (TCR) clones in blood at day 21 as a surrogate measure of anti-tumor immune response. Secondary objectives were safety and feasibility, 2-year disease-free survival (DFS), and predictive value of PD-L1 expression. Forty …

Transnational Corporate Law Litigation, William J. Moon

Duke Law Journal

For nearly half a century, a federal statute colloquially referred to as the Alien Tort Statute has served as a pivotal battleground over whether corporations violating law abroad can be subject to civil suits in the United States. The statute has been used to bring hundreds of lawsuits against corporations involved in some of the most heinous human rights abuses and environmental catastrophes taking place in foreign nations. Recent Supreme Court cases, however, have sounded the death knell for the viability of future cases by restricting the extraterritorial reach of federal statutes.

This Article presents a case for deterring corporate …

Utah Producers And Soil Health: Statewide Survey Results, Peggy Petrzelka, Jessica Ulrich-Schad, Matt Yost, Jenae Dean, Earl Creech, Linda Schott, Tony Richards, Kristy Davis

All Current Publications

To gain soil health perspectives and actions from a representative sample of Utah farmers and ranchers, a mail and online survey of Utah producers was conducted in 2024, focused on those who indicated they produced crops in 2023. In this report, we provide an overview of the survey results, with a specific focus on producers’ views on soil health, indicators used for soil health, factors that influence soil health adoption, and information sources used for soil health.

The Recipe For Health: How To Nourish Your Mind, Body, And Soul, Brian Chicoine

Advocate GME

Health is a state of complete physical, mental, and social well-being and not merely the absence of disease or infirmity (World Health Organization). People with Down syndrome can and should be active participants in promoting their health! In this webinar, Brian Chicoine, MD, will identify key ingredients of health, including nutrition, physical activity, sleep, stress management, meaningful activities and social connections, and social skills. He also will describe practical ways families can encourage their loved ones with Down syndrome to be healthy, and share free resources for people with Down syndrome, families and caregivers, and professionals.

Health Coaching Intervention Retained Anu-Adri Scores Over A 2-Year Period In Apoe E4 Carriers Among Older Adults At Risk For Alzheimer’S Disease, Michelle Gray, Anthony Campitelli, Ray G. Urbina, Megan Jones

Health, Human Performance and Recreation Faculty Publications and Presentations

Background: The Apolipoprotein epsilon 4 allele (APOE ε4) gene is known as the most prevalent genetic risk factor for Alzheimer’s disease (AD). However, many lifestyle risk factors that are modifiable influence the development of AD. Reducing the prevalence of risk factors can prevent or delay up to 33% of AD cases. Health coaching is known to improve health over time in older adults by using a motivational interviewing technique resulting in positive behavior modification. The purpose of this study was to determine if a 2-year health coaching intervention improves AD risk score among older adults at risk for AD aged …

Hell Comes With High Water: Hurricanes, Climate Change, And Louisiana's Dire Warning About The Erosion Of Our Speedy Trial Right, Robert F. Cerise

Duke Law Journal

The Sixth Amendment Speedy Trial Clause purportedly protects against undue delays in criminal cases. In order to obtain relief for a speedy trial violation, a defendant must show that a delay has lasted so long as to trigger the four-factor test in Barker v. Wingo (1972). Over time, however, states have codified procedural barriers to this speedy trial analysis. Simultaneously, courts have eroded Barker itself, namely by excusing “neutral” delays and by shifting the burden of proving prejudice resulting from such delays onto defendants. Louisiana is a particularly egregious example of these concerning trends, partly because hurricanes regularly disrupt the …