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Essential Utilities Inc V. Swiss Re Corporate Solutions Elite Insurance Corp

2025 Decisions

USDC for the Eastern District of Pennsylvania

Information Technology Management And Emotional Intelligence, Tina M. Muheim

Walden Dissertations and Doctoral Studies

Information technology (IT) employees often face high stress, burnout, and turnover, indicating a potential gap in IT leaders’ emotional intelligence (EI), which may hinder their ability to support and retain their teams effectively. Since IT plays a critical role in organizational performance and achieving strategic goals, addressing this gap is crucial for improving team well-being and organizational success. Grounded in EI theory, the purpose of this quantitative correlational study was to examine the relationship between IT managers’ EI subscales—assertiveness and interpersonal relationships—and their influence on the EI subscale, happiness/well–being indicator. The participants were 38 IT managers from U.S. organizations who …

Structured Staff Education On Incorporating Social Determinants Of Health Into Phq-9 Depression Screening For Improved Patient Outcomes, Gbemisola Elizabeth Mojelope

Walden Dissertations and Doctoral Studies

This doctor of nursing (DNP) project addressed a significant practice gap in an outpatient community healthcare setting, where staff lacked knowledge related to patient health questionnaire (PHQ-9) depression screening. The project’s focus question addressed whether staff education increased knowledge pertaining to the PHQ-9 depression screening. The initiative aimed to equip healthcare providers with the skills needed to incorporate social determinants of health in routine depression screenings, enhancing early identification of depressive symptoms and supporting targeted interventions. Fifteen healthcare workers voluntarily participated in the education. The in-person education initiative highlighted the importance of integrating social determinants of health (SDoH) into PHQ-9 …

Plural Molecular And Cellular Mechanisms Of Pore Domain, Timothy J Abreo, Emma C Thompson, Anuraag Madabushi, Kristen L Park, Heun Soh, Nissi Varghese, Carlos G Vanoye, Kristen Springer, Jim Johnson, Scotty Sims, Zhigang Ji, Ana G Chavez, Miranda J Jankovic, Bereket Habte, Aamir R Zuberi, Cathleen M Lutz, Zhao Wang, Vaishnav Krishnan, Lisa Dudler, Stephanie Einsele-Scholz, Jeffrey L Noebels, Alfred L George, Atul Maheshwari, Anastasios Tzingounis, Edward C Cooper

Faculty, Staff and Students Publications

KCNQ2 variants in children with neurodevelopmental impairment are difficult to assess due to their heterogeneity and unclear pathogenic mechanisms. We describe a child with neonatal-onset epilepsy, developmental impairment of intermediate severity, and KCNQ2 G256W heterozygosity. Analyzing prior KCNQ2 channel cryoelectron microscopy models revealed G256 as a node of an arch-shaped non-covalent bond network linking S5, the pore turret, and the ion path. Co-expression with G256W dominantly suppressed conduction by wild-type subunits in heterologous cells. Ezogabine partly reversed this suppression. Kcnq2G256W/+ mice have epilepsy leading to premature deaths. Hippocampal CA1 pyramidal cells from G256W/+ brain slices showed hyperexcitability. G256W/+ pyramidal …

Stability Of Lif Mirror Coatings On Space Telescopes At L2 Orbit, Devin M. Lewis

Theses and Dissertations

A team at Goddard Space Flight center has developed a coating of aluminum mirrors they term XeLiF. This coating has high ultraviolet reflection and improved environmental stability over similar LiF coatings. For these reasons, it is a potential candidate for the future Habitable Worlds Observatory (HWO) flagship space telescope mission. However, the stability of XeLiF at the planned L2 orbit of HWO has not been investigated. This study highlights the potential damage to XeLiF when irradiated by electrons that will be present at L2. This radiation will begin removing LiF after 6 years of exposure as well as start roughening …

2025 January 6, Faculty Senate Minutes, State University Of New York At Cortland

Minutes

Faculty Senate Minutes, 2025 January 6

SUNY Cortland Faculty Senate Committees Roster 2024-2025

Editorial: Unveiling The Next Generation Of Cancer Immunity & Immunotherapy, Mohanraj Sadasivam, Nethaji Muniraj, Chellappagounder Thangavel

Center for Translational Medicine Faculty Papers

No abstract provided.

The Latter-Day Saint Indian Placement Program: An Examination Through An Experiential Lens, Quinn Elise Christiansen

Theses and Dissertations

The Indian Placement Program, operated by the LDS Church from around 1947 to 2000, was influenced by the Church's belief in a connection between Native Americans to a Book of Mormon group known as the Lamanites. This group held a special status within the LDS Church because of their believed Israelite heritage as well as a prophecy promising their conversion in the last days. Spencer W. Kimball, motivated by both personal goals and his authority within the LDS Church, expanded on a successful experience of a young Native girl, Helen John, growing it into the broader Indian Placement Program. This …

Myo5b And The Polygenic Landscape Of Very Early-Onset Inflammatory Bowel Disease In An Ethnically Diverse Population, Ashleigh Watson, R Alan Harris, Amy C Engevik, Numan Oezguen, Maribeth R Nicholson, Sarah Dooley, Rachel Stubler, Lisa Forbes Satter, Lina B Karam, Richard Kellermayer

Faculty, Staff and Students Publications

Background: Genetic discovery in very early-onset inflammatory bowel disease (VEO-IBD) can elucidate not only the origins of VEO-IBD, but also later-onset inflammatory bowel disease. We aimed to investigate the polygenic origins of VEO-IBD in a cohort with a high proportion of Hispanic patients.

Methods: Patients with VEO-IBD who underwent whole exome sequencing at our center were included. Genes were categorized as genes of interest (GOIs) (129 genes previously described to be associated with VEO-IBD) or non-GOIs. VEO-IBD "susceptibility" single nucleotide variants (SNVs) were identified through enrichment compared with gnomAD (Genome Aggregation Database) and ALFA (Allele Frequency Aggregator) and were scored …

Evaluating The Contributions Of Nutrition Knowledge And Food Skills As Predictors Of Dietary Behavior, Diet Competence, And Diet Autonomy In Pre-Hypertensive Rural And Micropolitan Dwelling African American Adults In Alabama, Mary Catherine Robertson Lawson

All ETDs from UAB

Introduction: African American (AA) adults living in rural, Southeastern communities experience disproportionately high rates of obesity-related chronic diseases. Many factors contributing to this health disparity are related to negative Social Determinants of Health that have individual and community level impacts. Nutrition knowledge (NK) and food skills (FS) are forms of health literacy that have been understudied in rural-dwelling AA adults. Understanding their relationships with self-perceived diet competence, autonomy, motivations, as well as diet behaviors and health outcomes could inform the development of future health research and policy. Methods: A scoping review was conducted to identify key trends and information gaps …

Structured Staff Education On Incorporating Social Determinants Of Health Into Phq-9 Depression Screening For Improved Patient Outcomes, Gbemisola Elizabeth Mojelope

Walden Dissertations and Doctoral Studies

This doctor of nursing (DNP) project addressed a significant practice gap in an outpatient community healthcare setting, where staff lacked knowledge related to patient health questionnaire (PHQ-9) depression screening. The project’s focus question addressed whether staff education increased knowledge pertaining to the PHQ-9 depression screening. The initiative aimed to equip healthcare providers with the skills needed to incorporate social determinants of health in routine depression screenings, enhancing early identification of depressive symptoms and supporting targeted interventions. Fifteen healthcare workers voluntarily participated in the education. The in-person education initiative highlighted the importance of integrating social determinants of health (SDoH) into PHQ-9 …

Mechanisms Underlying Dilated Cardiomyopathy Associated With Fkbp12 Deficiency, Amy D Hanna, Ting Chang, Kevin S Ho, Rachel Sue Zhen Yee, William Cameron Walker, Nadia Agha, Chih-Wei Hsu, Sung Yun Jung, Mary E Dickinson, Md Abul Hassan Samee, Christopher S Ward, Chang Seok Lee, George G Rodney, Susan L Hamilton

Faculty, Staff and Students Publications

Dilated cardiomyopathy (DCM) is a highly prevalent and genetically heterogeneous condition that results in decreased contractility and impaired cardiac function. The FK506-binding protein FKBP12 has been implicated in regulating the ryanodine receptor in skeletal muscle, but its role in cardiac muscle remains unclear. To define the effect of FKBP12 in cardiac function, we generated conditional mouse models of FKBP12 deficiency. We used Cre recombinase driven by either the α-myosin heavy chain, (αMHC) or muscle creatine kinase (MCK) promoter, which are expressed at embryonic day 9 (E9) and E13, respectively. Both conditional models showed an almost total loss of FKBP12 in …

Dimensionality Reduction For Visualizing Spatially Resolved Profiling Data Using Spasne, Yuansheng Zhou, Chen Tang, Xue Xiao, Xiaowei Zhan, Tao Wang, Guanghua Xiao, Lin Xu

Faculty, Staff and Student Publications

Background: Spatially resolved profiling technologies to quantify transcriptomes, epigenomes, and proteomes have been emerging as groundbreaking methods for comprehensive molecular characterizations. Dimensionality reduction and visualization is an essential step to analyze and interpret spatially resolved profiling data. However, state-of-the-art dimensionality reduction methods for single-cell sequencing data, such as the t-distributed stochastic neighbor embedding (t-SNE) and uniform manifold approximation and projection (UMAP), were not tailored for spatially resolved profiling data.

Results: Here we developed a spatially resolved t-SNE (SpaSNE) method to integrate both spatial and molecular information. We applied it to a variety of public spatially resolved profiling datasets that were …

Intrinsic Adaptive Plasticity In Mouse And Human Sensory Neurons, Lisa A Mcilvried, John Smith Del Rosario, Melanie Y Pullen, Andi Wangzhou, Tayler D Sheahan, Andrew J Shepherd, Richard A Slivicki, John A Lemen, Theodore J Price, Bryan A Copits, Robert W Gereau

Faculty, Staff and Student Publications

In response to changes in activity induced by environmental cues, neurons in the central nervous system undergo homeostatic plasticity to sustain overall network function during abrupt changes in synaptic strengths. Homeostatic plasticity involves changes in synaptic scaling and regulation of intrinsic excitability. Increases in spontaneous firing and excitability of sensory neurons are evident in some forms of chronic pain in animal models and human patients. However, whether mechanisms of homeostatic plasticity are engaged in sensory neurons of the peripheral nervous system (PNS) is unknown. Here, we show that sustained depolarization (induced by 24-h incubation in 30 mM KCl) induces compensatory …

From Climate To Conflict: Unravelling Multidimensional Vulnerabilities Of Small-Scale Fisheries In The Jaffna Peninsula Of Sri Lanka, Mahinda Senevi Gunaratne, R. B. Radin Firdaus, Augustine Sosai Sihivaitthasan, Sarjiyanto Sarjiyanto, Mohd Hafiidz Jaafar

The Qualitative Report

Vulnerability studies have often centered on climate change and catastrophic climatic events. Contrary to this trend, this study explores the multidimensional vulnerabilities faced by small-scale fisheries (SSFs) in the Jaffna peninsula of Sri Lanka. We employed the Integrated Vulnerability Analysis for Sustainability (IVAS) Framework for this analysis. Data was collected through focus group discussions and key informant interviews using semi-structured questionnaires. We analyzed our data following Reflexive Thematic Analysis using ATLAS.ti software and identified 15 vulnerability drivers across five domains specific to the local context, revealing that SSFs in the Jaffna peninsula are highly susceptible to multiple vulnerabilities. Notably, the …

Origami Without Paper: Surrogate Folds For Origami-Inspired Mechanisms, Ivyann Oveson Running

Theses and Dissertations

Origami is a useful tool for generating novel spatial mechanisms that can address needs in a variety of fields. However, replicating paper folding in other materials requires surrogate folds---some way to approximate folding in otherwise rigid materials. This work presents a collection of potential surrogate fold designs suitable for use in origami-inspired applications. The designs are sorted into families and rated against several design characteristics of interest to engineers and designers to create the Surrogate Fold Catalog. The catalog is formatted to be searchable and filterable based on manufacturability, kinematic motion, and additional utility. Using this collection of surrogate folds …

Urban Sensing In The Era Of Large Language Models, Ce Hou, Fan Zhang, Yong Li, Haifeng Li, Gengchen Mai, Yuhao Kang, Ling Yao, Wenhao Yu, Yao Yao, Song Gao, Min Chen, Yu Liu

Faculty, Staff and Student Publications

Urban sensing has become increasingly important as cities evolve into the centers of human activities. Large language models (LLMs) offer new opportunities for urban sensing based on commonsense and worldview that emerged through their language-centric framework. This paper illustrates the transformative impact of LLMs, particularly in the potential of advancing next-generation urban sensing for exploring urban mechanisms. The discussion navigates through several key aspects, including enhancing knowledge transfer between humans and LLM, urban mechanisms awareness, and achieve automated decision-making with LLM agents. We emphasize the potential of LLMs to revolutionize urban sensing, offering a more comprehensive, efficient, and in-depth understanding …

Information Technology Management And Emotional Intelligence, Tina M. Muheim

Walden Dissertations and Doctoral Studies

Information technology (IT) employees often face high stress, burnout, and turnover, indicating a potential gap in IT leaders’ emotional intelligence (EI), which may hinder their ability to support and retain their teams effectively. Since IT plays a critical role in organizational performance and achieving strategic goals, addressing this gap is crucial for improving team well-being and organizational success. Grounded in EI theory, the purpose of this quantitative correlational study was to examine the relationship between IT managers’ EI subscales—assertiveness and interpersonal relationships—and their influence on the EI subscale, happiness/well–being indicator. The participants were 38 IT managers from U.S. organizations who …

Aspdb: An Integrative Knowledgebase Of Human Protein Isoforms From Experimental And Ai-Predicted Structures, Yuntao Yang, Himansu Kumar, Yuhan Xie, Zhao Li, Rongbin Li, Wenbo Chen, Chiamaka S Diala, Meer A Ali, Yi Xu, Albon Wu, Sayed-Rzgar Hosseini, Erfei Bi, Hongyu Zhao, Pora Kim, W Jim Zheng

Faculty, Staff and Student Publications

Alternative splicing is a crucial cellular process in eukaryotes, enabling the generation of multiple protein isoforms with diverse functions from a single gene. To better understand the impact of alternative splicing on protein structures, protein-protein interaction and human diseases, we developed ASpdb (https://biodataai.uth.edu/ASpdb/), a comprehensive database integrating experimentally determined structures and AlphaFold 2-predicted models for human protein isoforms. ASpdb includes over 3400 canonical isoforms, each represented by both experimentally resolved and predicted structures, and >7200 alternative isoforms with AlphaFold 2 predictions. In addition to detailed splicing events, 3D structures, sequence variations and functional annotations, ASpdb uniquely offers comparative analyses and …

Metsdb: A Knowledgebase Of Cancer Metastasis At Bulk, Single-Cell And Spatial Levels, Sijia Wu, Jiajin Zhang, Yanfei Wang, Xinyu Qin, Zhaocan Zhang, Zhennan Lu, Pora Kim, Xiaobo Zhou, Liyu Huang

Faculty, Staff and Student Publications

Cancer metastasis, the process by which tumour cells migrate and colonize distant organs from a primary site, is responsible for the majority of cancer-related deaths. Understanding the cellular and molecular mechanisms underlying this complex process is essential for developing effective metastasis prevention and therapy strategies. To this end, we systematically analysed 1786 bulk tissue samples from 13 cancer types, 988 463 single cells from 17 cancer types, and 40 252 spots from 45 spatial slides across 10 cancer types. The results of these analyses are compiled in the metsDB database, accessible at https://relab.xidian.edu.cn/metsDB/. This database provides insights into alterations in …

Crisprofft: Comprehensive Database Of Crispr/Cas Off-Targets, Grant Wang, Xiaona Liu, Aoqi Wang, Jianguo Wen, Pora Kim, Qianqian Song, Xiaona Liu, Xiaobo Zhou

Faculty, Staff and Student Publications

The CRISPR (clustered regularly interspaced short palindromic repeats)/Cas (CRISPR-associated protein) programmable nuclease system continues to evolve, with in vivo therapeutic gene editing increasingly applied in clinical settings. However, off-target effects remain a significant challenge, hindering its broader clinical application. To enhance the development of gene-editing therapies and the accuracy of prediction algorithms, we developed CRISPRoffT (https://ccsm.uth.edu/CRISPRoffT/). Users can access a comprehensive repository of off-target regions predicted and validated by a diverse range of technologies across various cell lines, Cas enzyme variants, engineered sgRNAs (single guide RNAs) and CRISPR editing systems. CRISPRoffT integrates results of off-target analysis from 74 studies, encompassing …

Fluorescence Lifetime Sorting Reveals Tunable Enzyme Interactions Within Cytoplasmic Condensates, Leyla E Fahim, Joshua M Marcus, Noah D Powell, Zachary A Ralston, Katherine Walgamotte, Eleonora Perego, Giuseppe Vicidomini, Alessandro Rossetta, Jason E Lee

Faculty, Staff and Students Publications

Ribonucleoprotein (RNP) condensates partition RNA and protein into multiple liquid phases. The multiphasic feature of condensate-enriched components creates experimental challenges for distinguishing membraneless condensate functions from the surrounding dilute phase. We combined fluorescence lifetime imaging microscopy (FLIM) with phasor plot filtering and segmentation to resolve condensates from the dilute phase. Condensate-specific lifetimes were used to track protein-protein interactions by measuring FLIM-Förster resonance energy transfer (FRET). We used condensate FLIM-FRET to evaluate whether mRNA decapping complex subunits can form decapping-competent interactions within P-bodies. Condensate FLIM-FRET revealed the presence of core subunit interactions within P-bodies under basal conditions and the disruption of …

Foundation Model Of Electronic Medical Records For Adaptive Risk Estimation, Pawel Renc, Michal K Grzeszczyk, Nassim Oufattole, Deirdre Goode, Yugang Jia, Szymon Bieganski, Matthew B A Mcdermott, Jaroslaw Was, Anthony E Samir, Jonathan W Cunningham, David W Bates, Arkadiusz Sitek

Faculty, Staff and Students Publications

Background: Hospitals struggle to predict critical outcomes. Traditional early warning systems, like NEWS and MEWS, rely on static variables and fixed thresholds, limiting their adaptability, accuracy, and personalization.

Methods: We previously developed the Enhanced Transformer for Health Outcome Simulation (ETHOS), an artificial intelligence (AI) model that tokenizes patient health timelines (PHTs) from electronic health records and uses transformer-based architectures to predict future PHTs. ETHOS is a versatile framework for developing a wide range of applications. In this work, we develop the Adaptive Risk Estimation System (ARES) that leverages ETHOS to compute dynamic, personalized risk probabilities for clinician-defined critical events. ARES …

An Exploratory Study Of Typeface Through The Use Of Cad Font List, Ayorinde Samuel Oluyemi

Journal of Art, Design and Music

This study categorizes typefaces using the default font lists from various Computer Aided Design (CAD) software to provide students with foundational knowledge for lettering design. Having been conducted as a descriptive research, it enhances existing literature by focusing on educating students on the essentials of typeface selection. The research examines font lists from Microsoft Office Word, CorelDraw X5, CorelDraw 2020, Adobe Illustrator CS6, Adobe Photoshop CS6, Adobe Photoshop CS5, and LibreCAD Office 7.5, analyzing 28 typefaces displayed on a 12 by 7-inch screen with a resolution of 1366x768. The study involved ten male participants, aged 25 to 40, all with …

Vol. 13 Iss. 2

Discussions

No abstract provided.

Vol 18. Iss. 1

Discussions

No abstract provided.

Eng 1000-003 College Composition Studio, Angela Vietto

Fall 2024

No abstract provided.

Global Scientific Production On Stakeholder Engagement In Community Forestry: A Bibliometric Analysis, Whisnu Febry Afrianto

Jurnal Penelitian Kehutanan Wallacea

Community forestry is a concept that presents management and utilization rights to local communities through empowering communities in sustainably managing forest resources and engaging them in forest conservation movements. This study aims to investigate the scope of stakeholder engagement in community forestry using a bibliometric review. Understanding stakeholders' participation in community forest management through a 30-year bibliometric analysis is essential for achieving historical insights, deciding conflicts, and discussing global forest landscape topics. The data was obtained from the Scopus database. Analysis of references with 808 publications and an annual publication growth rate of 6.49% (1981 – 2023) was used to …

Fieldnote 25: Black Men’S Health & Healing In The Academy | Dr. Raymond Adams On Prostate Cancer, Wellness, And Social Work, Venus Evans-Winters Dr.

Fieldnotes of a Black Woman Scholar: Research, Culture, and Wellness

In this episode of Writing What I Like: Fieldnotes of a Black Woman Scholar, Dr. Mildred Boveda (YouTube: @mboveda) and I are joined by Dr. Raymond Adams, a Black male social work professor whose research sheds critical light on prostate cancer and the health experiences of Black men. Dr. Adams brings a powerful voice to the intersection of public health, wellness, and academic life—unpacking the ways that systemic inequities shape Black men’s access to care, and how his scholarship is both a personal and political act of resistance. Together, we explore how Black men navigate wellness in the context of …

Can Clinical Findings At Admission Allow Withholding Of Antibiotics In Patients Hospitalized For Community Acquired Pneumonia When A Test For A Respiratory Virus Is Positive?, Ryan Ward, Alejandro J Gonzalez, Justin A Kahla, Daniel M Musher

Faculty, Staff and Students Publications

BACKGROUND: Current guidelines recommend empiric antibiotic therapy for patients who require hospitalization for community-acquired pneumonia (CAP). We sought to determine whether clinical, imaging or laboratory features in patients hospitalized for CAP in whom PCR is positive for a respiratory virus enable exclusion of bacterial coinfection so that antibiotics can be withheld.

METHODS: For this prospective study, we selected patients in whom an etiologic diagnosis was likely to be reached, namely those who provided a high-quality sputum sample at or shortly after admission, and in whom PCR was done to test for a respiratory virus. We performed quantitative bacteriologic studies on …