Digital Commons Network^™

Impact Of Perioperative Organ Injury On Morbidity And Mortality In 28 Million Surgical Patients, Felix Kork, Yafen Liang, Adit A Ginde, Xiaoyi Yuan, Rolf Rossaint, Hongfang Liu, Alex S Evers, Holger K Eltzschig

Faculty, Staff and Student Publications

Perioperative organ injury contributes to morbidity and mortality of surgical patients. This cohort study included all elective and emergent surgeries in Germany over 4 years to address the impact of perioperative organ injuries on outcomes. We analyzed 28,350,953 cases. In-hospital mortality was 1.4% (n = 393,157), and 4.4% of cases (n = 1,245,898) experienced perioperative organ injury. Perioperative organ injury was associated with 9-fold higher odds of death and prolonged hospital stay by 11.2 days. Acute kidney injury had the highest incidence (2.0%) and was associated with 25.0% mortality. While delirium had the second highest incidence (1.5%), it was associated …

Can Endothelin-1 Help Address The Diagnostic And Prognostic Challenges In Multimorbid Acute Heart Failure Patients?, Bianca-Ana Dmour, Minerva Codruta Badescu, Cristina Tuchiluș, Corina Maria Cianga, Daniela Constantinescu, Nicoleta Dima, Ștefania Teodora Duca, Awad Dmour, Alexandru Dan Costache, Maria-Ruxandra Cepoi, Adrian Crișan, Sabina Andreea Leancă, Cătălin Loghin, Ionela-Lăcrămioara Șerban, Irina Iuliana Costache-Enache

Faculty, Staff and Student Publications

The management of acute heart failure (AHF) is becoming increasingly complex, especially in patients with multiple comorbidities. Endothelin-1 (ET-1), a vasoconstrictive peptide, is an important mediator of neurohormonal activation, endothelial dysfunction, and cardiac remodeling-key processes involved in the pathogenesis of AHF. The aim of our study was to evaluate the diagnostic and prognostic performance of ET-1 in multimorbid AHF patients, compared to established markers such as amino terminal pro B-type natriuretic peptide (NT-proBNP) and high-sensitivity cardiac troponin I (hs-cTnI). We conducted a single-center prospective study including 76 patients; 54 with AHF and 22 serving as controls. Upon admission, all patients …

Spectrum, Volume 54, Issue 10, Sacred Heart University

Newspapers (Obelisk & Spectrum)

Highlights include: What’s New at SHU (in Dingle)? - Give It Up for Giving Day! - SHU Provides a Forum for the “Voices of Tomorrow”- Dance Program Seniors Prepare for Their Final Bow - From Building Blocks to Blockbuster - SCMA Seniors Create Capstone Projects - Five Pioneers Looking to the Pros

Greenhouse Gas Emissions From Flood-Irrigated Rice As Affected By Phosphorus Fertilizer Source, Chandler M. Arel, Kristofor R. Brye, Diego Della Lunga, Trenton L. Roberts, Richard Adams

Crop, Soil and Environmental Sciences Faculty Publications and Presentations

Research into alternative phosphorus (P) fertilizer sources that may be able to supplement P resources is necessary. Struvite (MgNH4PO4 · 6H2O) can be made by removing excess nutrients from waste sources and may reduce greenhouse gas (GHG) emissions from cropping systems. This study sought to quantify GHG [i.e., methane (CH4), nitrous oxide (N2O), and carbon dioxide (CO2)] fluxes, season-long emissions, and net GHG emissions from chemically precipitated struvite (CPST) and synthetic and real-wastewater-derived electrochemically precipitated struvite (ECST) compared to monoammonium phosphate (MAP) and an unamended control (UC) from flood-irrigated rice (Oryza sativa) grown in P-deficient, silt loam soil in a …

Pilrα Sustains Microglial Capacity To Process Myelin In A Mouse Model Of Demyelination, Kent Lin

Arts & Sciences Graduate Student Theses and Dissertations

Alzheimer's disease (AD) is characterized by amyloid-β (Aβ) plaques, neurofibrillary tangles, and neurodegeneration. Microglia, the resident immune cells of the central nervous system (CNS), play a crucial role in AD pathogenesis by containing the spreading of Aβ plaques. Genetic studies have associated a variant of the receptor Paired Immunoglobulin-like Type 2 Receptor Alpha (PILRα) with reduced risk for AD. PILRα is a receptor found on myeloid cells, such as microglia, that binds to endogenous cell surface glycoproteins and sends inhibitory signals within the cell. Additionally, it serves as an entry receptor for Herpes Simplex Virus 1. To elucidate the role …

Essays On Monetary Economics, Joseph Kachovec

Arts & Sciences Graduate Student Theses and Dissertations

Chapter I builds a quantitative New-Keynesian model with a central bank balance sheet, fiscal policy, and a representative financial intermediary facing uncertainty to show how interest rate policy has an additional counter-cyclical fiscal impact via central bank income when reserves are abundant as opposed to scarce. A counterfactual analysis between the US economies with small and large central bank balance sheets of 2005 and 2018 shows that in response to demand, supply, and government spending shocks, the real effects of identical interest rate changes are amplified in the abundant reserves economy. In response to a 1% preference shock, cumulative fluctuations …

Ai-Based Accessibility Widget (Aibaw) Shortcomings For Blind Web Users, Joshua A. Rovira

LSU Master's Theses

With legal, ethical, and financial motivations to make their websites more accessible, many businesses and sites have begun to employ the use of artificial intelligence (AI) based widgets to automatically make necessary modifications to their sites' pages and subdomains. In this work, we conduct a qualitative case study to determine the efficacy of these AI tools as they pertain specifically to blind users. We analyze pages from twelve websites using accessiBe's AI accessibility widget and provide a taxonomy of their violations against the Web Content Accessibility Guidelines (WCAG) 2.1 level AA compliance. We found each website to bear numerous violations …

An Unsupervised Map Of Excitatory Neuron Dendritic Morphology In The Mouse Visual Cortex, Marissa A Weis, Stelios Papadopoulos, Laura Hansel, Timo Lüddecke, Brendan Celii, Paul G Fahey, Eric Y Wang, J Alexander Bae, Agnes L Bodor, Derrick Brittain, Joann Buchanan, Daniel J Bumbarger, Manuel A Castro, Forrest Collman, Nuno Maçarico Da Costa, Sven Dorkenwald, Leila Elabbady, Akhilesh Halageri, Zhen Jia, Chris Jordan, Dan Kapner, Nico Kemnitz, Sam Kinn, Kisuk Lee, Kai Li, Ran Lu, Thomas Macrina, Gayathri Mahalingam, Eric Mitchell, Shanka Subhra Mondal, Shang Mu, Barak Nehoran, Sergiy Popovych, R Clay Reid, Casey M Schneider-Mizell, H Sebastian Seung, William Silversmith, Marc Takeno, Russel Torres, Nicholas L Turner, William Wong, Jingpeng Wu, Wenjing Yin, Szi-Chieh Yu, Jacob Reimer, Philipp Berens, Andreas S Tolias, Alexander S Ecker

Faculty, Staff and Students Publications

Neurons in the neocortex exhibit astonishing morphological diversity, which is critical for properly wiring neural circuits and giving neurons their functional properties. However, the organizational principles underlying this morphological diversity remain an open question. Here, we took a data-driven approach using graph-based machine learning methods to obtain a low-dimensional morphological "bar code" describing more than 30,000 excitatory neurons in mouse visual areas V1, AL, and RL that were reconstructed from the millimeter scale MICrONS serial-section electron microscopy volume. Contrary to previous classifications into discrete morphological types (m-types), our data-driven approach suggests that the morphological landscape of cortical excitatory neurons is …

Documents From The April 9, 2025 Meeting Of The Associated Students Of The University Of Montana (Asum)., Associated Students Of The University Of Montana

Senate Meeting Agendas and Minutes, 2007-Present

Minutes and agenda from the April 9, 2025 Meeting of the Associated Students of the University of Montana (ASUM).

Mitochondrial Responses To Conventional And Ultra-High Dose Rate (Flash) Radiation, Emily G Caggiano, Alan Lopez Hernandez, Trey Waldrop, Kevin Liu, Henry Gatica-Gutierrez, Sofía Vargas-Hernández, Nefetiti Mims, Ariana Acevedo-Diaz, Brett Velasquez, Denae Neil, Edgardo Aguilar, Matthew D Meyer, Gloria V Echeverria, Albert C Koong, Michael T Spiotto, Anna-Karin Gustavsson, Emil Schüler

Faculty, Staff and Students Publications

Purpose: Ultra-high dose rate (>40 Gy/s, FLASH) radiation therapy (RT) provides equivalent tumor control while reducing normal tissue toxicity relative to conventional dose rate (CONV) RT. However, the mechanisms underlying the observed FLASH effect are unknown. We hypothesized that the preservation of mitochondrial integrity in nontumorigenic cells by FLASH RT could be a key factor in reducing normal tissue toxicity and improving overall treatment outcomes.

Methods: We examined mitochondrial health and function after CONV and FLASH in vitro, ex vivo, and in vivo through assays of metabolic flux, mitochondrial membrane potential, mitochondrial reactive oxygen species (ROS), mitochondrial DNA damage …

The Medial Olivocochlear Efferent Pathway Potentiates Cochlear Amplification In Response To Hearing Loss, Patricia M Quiñones, Michelle Pei, Hemant Srivastava, Ariadna Cobo-Cuan, Marcela A Morán, Bong Jik Kim, Clayton B Walker, Michael J Serafino, Frank Macias-Escriva, Juemei Wang, James B Dewey, Brian E Applegate, Matthew J Mcginley, John S Oghalai

Faculty, Staff and Students Publications

The mammalian cochlea receives efferent feedback from the brain. Many functions for this feedback have been hypothesized, including on short timescales, such as mediating attentional states, and long timescales, such as buffering acoustic trauma. Testing these hypotheses has been impeded by an inability to make direct measurements of efferent effects in awake animals. Here, we assessed the role of the medial olivocochlear (MOC) efferent nerve fibers on cochlear amplification by measuring organ of Corti vibratory responses to sound in both sexes of awake and anesthetized mice. We studied long-term effects by genetically ablating the efferents and/or afferents. Cochlear amplification increased …

Understanding Infection, Viral Exacerbation And Respiratory Symptoms At Admission-Longitudinal (Universal) Study: A Prospective Observational Cohort Study Protocol, Universal Study Group, Tommaso Morelli, Martha Purcell, Pedro Rodrigues, Charles Roberts, Olivia Cox, Paul H. Lee, Kerensa Thorne, Alexander Allen, Angelica Cazaly, Jacqueline Nuttall, James Raftery, Gareth Griffiths, Andrew Cook, Nicola White, Neil J. Greening, Matthew Pavitt, James Myerson, Stefan J. Marciniak, Cyrus Daneshvar, Michael G. Crooks, Philip Mitchelmore, James D. Chalmers, Salman Siddiqui, Karl J. Staples, Tristan William Clark, Anna Freeman, Tom Wilkinson, Emma Tilt

Peninsula Medical School

Background Respiratory viral infections (RVIs) are a significant cause of morbidity and hospital admission worldwide. However, the management of most viral infection-associated diseases remains primarily supportive. The recent COVID-19 pandemic has underscored the urgent need for a deeper understanding of RVIs to improve patient outcomes and develop effective treatment strategies. The Understanding Infection, Viral Exacerbation and Respiratory Symptoms at Admission-Longitudinal Study is an observational study which addresses this need by investigating the heterogeneity of RVIs in hospitalised adults, aiming to identify clinical and biological predictors of adverse outcomes. This study aims to bridge critical knowledge gaps in the clinical course …

Co-Designing A Web-Based And Tablet App To Evaluate Clinical Outcomes Of Early Psychosis Service Users In A Learning Health Care Network: User-Centered Design Workshop And Pilot Study, Kathleen E Burch, Adam B Wilcox, Et Al.

2020-Current year OA Pubs

BACKGROUND: The Early Psychosis Intervention Network of California project, a learning health care network of California early psychosis intervention (EPI) programs, prioritized incorporation of community partner feedback while designing its eHealth app, Beehive. Though eHealth apps can support learning health care network data collection aims, low user acceptance or adoption can pose barriers to successful implementation. Adopting user-centered design (UCD) approaches, such as incorporation of user feedback, prototyping, iterative design, and continuous evaluation, can mitigate these potential barriers.

OBJECTIVE: We aimed to use UCD during development of a data collection and data visualization web-based and tablet app, Beehive, to promote …

Analysis Of Diversity, Equity, And Inclusion Initiatives In Environmental Education In Wisconsin, Jody Bauer, Robert Hougham, Sarah Burgess

Mid-Western Educational Researcher

This research aims to identify the quantity, quality, and condition of diversity, equity, and inclusion (DEI) efforts in environmental education in Wisconsin. Researchers surveyed environmental education organizations across the state to collect and disseminate data related to the status and needs of these initiatives, and to identify areas of strength, improvement, or future staff learning opportunities. Some of the current DEI concerns in environmental education focus on the lack of diversity represented by staffing, achievement gaps represented by marginalized students, and a lack of overall accessibility to the outdoors or outdoor education for diverse communities. Findings from this study reinforce …

Ethnic/Racial Differences In Reading College Readiness: A Texas Pre- And Post-Pandemic Analysis, Neil A. Laminack, John R. Slate, Janene W. Hemmen

School Leadership Review

In this statewide multiyear investigation, the extent to which differences were present on the STAAR English I End-of-Course exam for Texas high school students as a function of their ethnicity/race (i.e., Asian, Black, Hispanic, and White) for the 2017-2018, 2018-2019, 2020-2021, 2021-2022, and 2022-2023 school years were examined. Archival data from the Public Education Information Management System were obtained for the two school years pre-pandemic (2017-2018 and 2018-2019) and the three years post-pandemic (2020-2021, 2021-2022, and 2022-2023). Across all five school years and on all three grade-level standards, Approaches, Meets, and Masters, Asian students met the standards at the highest …

Exploring Teaching And Learning In Diverse Multilingual Spaces, Juliet M. Luther

Journal of Multilingual Education Research

None

Critical Language Awareness For Spanish-English Bilingual 5th Graders, Mary Hudgens Henderson

Journal of Multilingual Education Research

Critical Language Awareness (CLA) instruction can and should be a part of K-12 education. This study reports on a CLA unit taught to Spanish-English bilingual 5^th graders enrolled in a dual language bilingual classroom in the southwest U.S. Scores from a pretest and three posttests administered throughout the school year were compared to peer bilingual and monolingual 5^th graders in an English-only classroom who did not participate in CLA instruction. A Mixed ANOVA repeated measures analysis found that bilingual students in the dual language bilingual classroom had high levels of CLA knowledge both before and after participating in …

Voices From The Frontline: School Leaders On Effective Communication, Abdelnasser Hosni Hussein

School Leadership Review

This qualitative cross-case study aimed to explore effective communication in suburban and urban schools. The study investigated K-12 leaders' perceptions of effective communication with parents in suburban and urban school districts. Three open-ended questions guided the research: 1) What are principals’ perceptions of effective communication with parents?, 2) What are principals’ perceptions of effective strategies of school-home communication?, and 3) What are the barriers that may obstruct effective communication between principals and families? This cross-case study is unique as it focused on school leaders' perspectives to define effective communication. Strategies, methods, and barriers were identified by participant school leaders. The …

Leading With Data, Leading With Ethics: A Practical Ethics Guide In Statistics And Data Analysis For Educational Leaders, Elliott Ostler, Tami Williams, John Schultz

School Leadership Review

Abstract:

In today's data-driven and data-informed educational landscape, leaders face increasing pressure to make decisions and present results based on what appear to be comprehensive statistical analyses. However, the ethical implications of these responsibilities can be complex, particularly when statistical results carry the potential to be miscommunicated, misinterpreted, misrepresented, or even misused. This article explores some of the critical aspects of ethical statistical practices in educational leadership and provides practical considerations for leaders in using and presenting data responsibly. Specifically, the narrative contained herein emphasizes ethical practice associated with statistics and data analysis, not simply the ethics of general research …

Economic Status Of Texas Grade 8 Emergent Bilingual Students And Reading: A Pre- And Post-Pandemic Investigation, Teresa A. Dealba, John R. Slate, Clare A. Resilla

School Leadership Review

In this investigation, we examined differences in performance on the Texas state-mandated reading assessment for Emergent Bilingual students by their economic status (i.e., in poverty, not in poverty). Archival data were obtained from the Texas Education Agency Public Education Information Management System for Grade 8 students for the two pre-pandemic school years (2017-2018 and 2018-2019) and three post-pandemic school years (2020-2021, 2021-2022, and 2022-2023). A lower percentage of Emergent Bilingual students in poverty met the Grade 8 STAAR Reading Approaches Grade Level standard than Emergent Bilingual students not in poverty. For the Meets Grade Level and Masters Grade Level standards, …

Design And Mixing Performance Of Passive Micromixers: A Critical Review, Afzal Husain, Asharul Islam Khan, Wasim Raza, Nabeel Al-Rawahi, Nasser Al-Azri, Abdus Samad

The Journal of Engineering Research

This study extracts and reports notable findings on passive micromixers by conducting an exhaustive review of designs, their features, and mixing performance. The study has covered the relevant articles on passive micromixers published from 2010 to 2020. The analysis of filtered and selected articles sums up passive micromixers into four categories: designed inlets, designed mixing-channel, lamination-based, and flow obstacles-based. The prominent mixing channel categories identified in the study are split-and-recombine (SAR), convergent-divergent (C-D), and mixed (SAR, C-D, and others). Moreover, differences in mixing channel designs, number of inlets, and evaluation methods have been used in comparing the mixing performance of …

Investigation Of Noise Exposures, Perception, And Health Effects In Different Microenvironments In A University Community, Patrick Amoatey, Issa Al-Harthy, Khalifa Al-Jabri, Abdullah Al-Mamun, Mahad Baawain

The Journal of Engineering Research

This study aims to assess noise levels in selected outdoor and indoor microenvironments in a University community in Oman. The perception of noise levels within the Sultan Qaboos University campus was investigated through a survey study. Also, the effect of exposed noise levels on annoyance and sleep disturbance were predicted including their potential risk on cardiovascular health. Among all the measured parameters, it was found that outdoor (41.6%-50%) and indoor (38.5%-46.2%) microenvironments have exceeded the critical levels of 55 dB during morning and afternoon periods. The respondents (698 people) identified traffic and indoor building-related activities as the main sources of …

Investigation Of The Thermal Comfort And Productivity In Japanese Mixed-Mode Office Buildings, Supriya Khadka, Mishan Shrestha

The Journal of Engineering Research

This study investigates the overall comfort and productivity of Japanese office workers in mixed-mode office buildings. The indoor thermal environment is adjusted using the air-conditioning in Japanese office buildings to maintain thermal comfort and productivity. Thus, it is necessary to research thermal comfort and productivity to understand how occupants prepare themselves to be at a comfortable temperature and perform their daily tasks under mixed-mode (MM) and free-running (FR) modes. Environmental parameters such as air temperature, relative humidity, and so on were measured in 17 Japanese office buildings with the help of digital instruments, and thermal comfort transverse surveys were conducted …

Extreme Cold Discomfort In Extreme Hot Climates, A Study Of Building Overcooling In Office Buildings In Qatar, Abdulla Alnuaimi, Sukumar Natarajan

The Journal of Engineering Research

Indoor cold discomfort in Qatar due to “building overcooling” is increasing, as air-conditioning prevails, and global temperatures rise. Overcooling is not dependent only on the inappropriate design of cooling systems, but on “international” thermal comfort standards that are not customized for warm climates. International standards are unintentionally biased towards cooler climates and cultures, the application of which in warm climates result in colder indoor temperatures observed by building occupants and increased cooling energy demand. Overcooling is an over-expenditure of energy, resulting in uncomfortably cold indoor thermal conditions, and unnecessary carbon emissions. In this study, the analysis of field data from …

Occupant Perception Of Thermal Comfort In Sleep Environments In Qatar, Madhavi Indraganti, Farsana Kutty, Reem Ali, Lulwa Al Noaimi, Saaeda Al-Bader, Maryam Adel Al Mulla

The Journal of Engineering Research

A thermal comfort field survey in sleep environments in winter and spring seasons in Qatar collected 833 sets of objective and subjective thermal and sleep quality responses before going to bed and after getting up. The subjects felt cooler sensations most of the time, preferred warmer sensations and the sleep environments are considered comfortable overall. Griffiths comfort temperature (Tc) was 24.3 ˚C and 20.2 ˚C in FR and AC modes respectively. Subjects used air-conditioner (AC)s adaptively in heating mode in winter. In 82.7% cases in air-conditioned (AC) mode, the comfort temperature was below the lower limit of the international standard. …

In Achieving The Most Of Limited Research Budget For Engineering Research Projects: A Case Study At Sultan Qaboos University, M Zarog

The Journal of Engineering Research

Motivating engineering research in universities with limited or tight research budgets is a challenging task. There is always a conflict between researchers attempting to secure enough funds to ease their own research, and funding bodies and universities trying to achieve high quality research while lowering research expenses. This conflict leads to a situation where universities and researchers cannot achieve their goals altogether. This study attempts to partially resolve this issue by optimizing research expenditure for the benefit of both universities and researchers and suggests some policies regarding what type of research (modelling based or experimental based) universities should support. Other …

Carrier Based Pwm Technique And Adaptive Neural Network Based Rotor Resistance Estimator For The Performance Enhancement Of Vector Controlled Induction Motor Drives, Venkadesan A

The Journal of Engineering Research

In this paper, the carrier based Pulse Width Modulation (PWM) technique and neural network based rotor resistance estimator are proposed for vector controller Induction motor (IM) drives. The popular sine PWM is used for induction motor drive. The popular sine PWM has poor harmonic profile and (DC) utilization. The space vector modulation (SVM) technique overcomes the disadvantages of sine PWM. But SVM is computationally complex. Hence a simple PWM technique namely “carrier based PWM technique” similar to SVM is identified and proposed for vector controlled IM drive. The experimental set up is built up and the performance of carrier based …

Load-Displacement Curves Of Spot Welded, Bonded, And Weld-Bonded Joints For Dissimilar Materials And Thickness, E.A. Al-Bahkali

The Journal of Engineering Research

Three-dimensional finite element models of spot welded, bonded and weld-bonded joints are developed using ABAQUS software. Each model consists of two strips with dissimilar materials and thickness and is subjected to an axial loading. The bonded and weld-bonded joints have specific adhesive thickness. A detailed experimental plan to define many properties and quantities such as, the elastic - plastic properties, modulus of elasticity, fracture limit, and properties of the nugget and heat affected zones are carried out. Experiments include standard testing of the base metal, the adhesive, the nugget and heat affected zone. They also include employing the indentation techniques, …

Bach Against Modernity, Mark Peters

Yale Journal of Music & Religion

A book review is presented for Bach against Modernity, authored by Michael Marissen, by Mark Peters.

Memory, Music, Manuscripts: The Ritual Dynamics Of Kōshiki In Japanese Sōtō Zen, Junko Oba

Yale Journal of Music & Religion

A book review is presented for Memory, Music, Manuscripts: The Ritual Dynamics of Kōshiki in Japanese Sōtō Zen, authored by Michaela Mross, by Junko Oba.