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The Bulletin: Sidney Kimmel Medical College At Thomas Jefferson University, Volume 104, Issue 1, Summer 2026

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

This issue includes:

• 5 - Dean's Column
• 6 - Time Machine
• 8 - TJU News
• 12 - Discovery
• 14 - Remembering a Renaissance Man
• 20 - A Conversation with a Jefferson Legend
• 24 - 2026 Scholarship Celebration Recap
• 26 - Bridging Gaps - and Building Bridges
• 28 - Looking Out for the Next in Line
• 30 - Welcome SKMC Class of 2030
• 32 - Meet Our Alumni
• 34 - Class Ambassadors
• 36 - A Message From the SKMC Alumni Board President
• 38 - Class Notes
• 42 - In Memoriam
• 46 - By the Numbers

Christianity, Gender Identity, Parents’ Rights: Book Censorship Discourse In Tennessee Communities, Janet Kesterson Isbell, Shawn Hinkel

The Southeastern Librarian

Hate and hostility toward the lesbian, gay, bisexual, transgender, queer+ (LGBTQ+) community and people of color, inflamed in recent years by political extremism and radical conservatism, have permeated many areas of society. One context where hostilities have emerged in the past decade is public debate surrounding book challenges, which prompted a yearlong investigation into the polarizing phenomenon of book censorship in the United States. After extensive reading of media reports from around the nation, the authors focused on public discourse related to book challenges in Tennessee public and school libraries, where debate was contentious, librarians were threatened, and the state’s …

Haint Country: Dark Folktales From The Hills And Hollers, Samantha Duncan

The Southeastern Librarian

Haint Country: Dark Folktales from the Hills and Hollers
Matthew R. Sparks and Olivia Sizemore
Lexington: University Press of Kentucky, 2024
ISBN: 9781985900974
216 pp., $24.95 (Pbk)

Antibody-Oligonucleotide Conjugates: An Emerging Modality For Precision Rna Therapeutics, Chen-Hsu Yu, Summer Y Y Ha, Zhiqiang An, Kyoji Tsuchikama, Wenbo Li

The Brown Foundation: Institute of Molecular Medicine

RNA-targeting therapeutics have enormous potential to precisely target disease-causing RNAs, extending beyond the traditional limits of "druggability" for small molecules, antibodies, and protein-targeting cell therapies. However, one crucial limitation is that RNA-targeting drug modalities (such as oligonucleotides) cannot effectively reach diseased tissue or cell types. Antibody-oligonucleotide conjugates (AOCs) emerge as a promising frontier in aiding RNA therapeutics by harnessing antibodies to deliver drug modalities to target specific RNAs in desired tissues or cells. In this Review, we summarize the critical components of AOCs, key considerations for their design and manufacturing, ongoing AOCs in preclinical/clinical development, and disease indications. We discuss …

Nano-Bio Interfacial Effects Modulating Protein Adsorption In Dialdehyde Lentinan-Crosslinked Polysaccharide Sponges Reinforced With Zein Nanoflowers, Dorota Chelminiak-Dudkiewicz, Miloslav Machacek, Hana Janová, Klara Konecna, Ondrej Jandourek, Jana Kejmarová, Kinga Mylkie, Aleksander Smolarkiewicz-Wyczachowski, Marta Ziegler-Borowska

The Brown Foundation: Institute of Molecular Medicine

The interfacial organization of porous biomaterials critically influences protein adsorption and subsequent cell-material interactions at hydrated biointerfaces relevant to wound-contacting environments. Herein, hybrid sponges were developed by rationally assembling chitosan, lentinan, levan, and fucoidan into a covalently defined macromolecular network featuring nano-bio interfacial effects. The materials were designed to modulate interfacial biological performance via engineered pore-wall structures, with protein-layer formation at sponge interfaces associated with downstream cell-material responses. A dialdehyde lentinan was deliberately employed to establish a chemically defined pore-wall interface via dense Schiff-base junctions with chitosan. The incorporation of zein nanoflowers introduced additional nanoscale structure features, providing additional anchoring …

Cost Utility Analysis Of Fluticasone Exhalation Delivery System Versus Budesonide Nasal Irrigation For Chronic Rhinosinusitis With Nasal Polyps, Daniel Xiao, Martin J Citardi, William C Yao, Amber U Luong

The Brown Foundation: Institute of Molecular Medicine

Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) is managed after sinus surgery with topical corticosteroids. Given limited distribution of nasal steroid sprays, patients have the option of either steroid nasal irrigation (SNI) or exhalation delivery system with fluticasone (EDS-FLU). This study evaluates the cost-effectiveness of EDS-FLU compared to SNI for CRSwNP.

Methods: A cohort-style Markov decision-tree economic model with a 33-year time horizon was developed in TreeAgePro. Because EDS-FLU is not currently covered by Medicare, costs of medications were estimated using retail pricing. A willingness-to-pay threshold of $50,000/quality adjusted life year (QALY) was used to determine cost-effectiveness. One-way and probabilistic …

Functional Characterization Of Uhrf1 Variants In Facilitating Dna Methylation, Bigang Liu, Kaila Nayvelt, Swanand Hardikar, Kimie Kondo, Marcos R Estecio, Xiaodong Cheng, Taiping Chen

The Brown Foundation: Institute of Molecular Medicine

Ubiquitin-like with plant homeodomain (PHD) and really interesting new gene (RING) finger domains 1 (UHRF1) is essential for DNA methylation inheritance. However, the functional impacts of several natural and engineered UHRF1 variants are either insufficiently characterized or obscured by conflicting results, with some discrepancies likely stemming from cellular toxicity and adaptive responses induced by DNA methylation changes. In this study, we utilized mouse embryonic stem cells (mESCs)-which uniquely tolerate the complete loss of DNA methylation-to evaluate the functional consequences of clinical mutations, isoform variation, and epitope tagging. Using rescue experiments in Uhrf1-deficient mESCs, we characterized two UHRF1 mutations identified in …

Da Mosang Tarsier Series: Developing Digital Bullying Prevention Materials For Filipino Parents Of Grade School Students, Rudy M. Danganan Jr., Ann Christine V. Braga, Maria Kristina S. Alfonso, Romelito Manuel D.S. Clorina, Ma. Regina Hechanova

Children and Families

Bullying remains a significant public health and educational concern worldwide and is particularly prevalent in Philippine public schools, with Grade 7 students identified as a vulnerable group. Although the Anti-Bullying Act of 2013 (Republic Act No. 10627) mandates school-based policies and procedures, persistent implementation gaps underscore the need to strengthen home–school partnerships and equip parents with practical, culturally grounded response strategies. This paper describes the development of the Da Mosang Tarsier Series, a set of digital psychoeducational comic strips designed for Filipino parents of Grade 7 students. Guided by a user-centered design (UCD) framework, the project began with a Generative …

Just Opt For Caesarean Section And Pick The Birthdate': A Qualitative Study Exploring Women's Delivery Preferences After Caesarean Section In Urban Tanzania, Daudi Gidion, Columba Mbekenga, Miriam Mgonja, Marleen Temmerman, Muzdalfat Abeid

Obstetrics and Gynaecology, East Africa

Objectives To explore perspectives, preferences and decision-making regarding mode of delivery after a previous caesarean section among women in urban Tanzania.

Design A descriptive qualitative study using semi-structured in-depth interviews. Data were analysed using thematic analysis.

Setting A private tertiary hospital in Dar es Salaam, Tanzania.

Participants 11 women with one previous caesarean section who delivered at the study site were interviewed on the third day after delivery. Participants were purposively sampled to include both modes of delivery: five women underwent repeat caesarean section and six attempted a trial of labour after caesarean (TOLAC).

Results Thematic analysis identified four key …

Health Beliefs And Lung Cancer Screening Uptake Among Eligible Asian Americans In Philadelphia, Pennsylvania, United States, Julia G. Katcher, Kuang-Yi Wen, Christine S. Shusted, Jessica Liang, Kyunghee Koh, Hee-Soon Juon, Julie Barta

Department of Medical Oncology Faculty Papers

OBJECTIVE: Asian Americans experience disproportionately late-stage lung cancer diagnoses and lower lung cancer screening (LCS) rates than other racial groups. This study evaluated the association between the

METHODS: This pilot randomized controlled trial, conducted April 2023-January 2024 within a Philadelphia health system, tested a culturally and linguistically tailored intervention led by community health workers. LCS completion and LCS-Health Belief Scale (LCS-HBS) responses were compared between control and intervention participants (

RESULTS: LCS completion was higher in the intervention group (45%) than in the control (31.3%). Control participants who completed LCS reported higher perceived lung cancer risk, greater perceived benefits, and …

Aadej Comm 12 2 2026

AADEJ - The Communicator

The Communicator is the official publication of the American Association of Dental Editors & Journalists (AADEJ), promoting awareness of the association’s activities and offering valuable insights for dental editors and journalists to enhance their publications. It is published quarterly, distributed digitally via email to members, and posted on the Association’s website at aadej.org, with archives on ADA Commons. Regular contributions from the Editor-in-Chief, Executive Director, President, and Associate Editor cover various topics.

Math 119: Math For Elementary School Teachers Instructor Guide, Seth Lehman

Open Educational Resources

OER instructor guide for Math 119: Math for Elementary School Teachers at Queens College

Resisting Dualism In Contemporary Movement Building: Lessons From The Zapatista Movement On Creating Assertive, Insurgent, And Generative Praxis, Nico Killian

University Honors Theses

The common struggle of social movements, revolutionary and otherwise, in the contemporary era is how to establish a collective capable of asserting its politics via grassroots organizing in the face of the logic of global capitalism that atomizes communities, reconfigures the role of the state, and unleashes the fragmentizing and simultaneously totalitizing forces of the global market. Discourse regarding effective movement building in the contemporary era often falls into two dualistic avenues of resistance - complete autonomy that rejects any engagement or affiliation with political structures out of fear that it would result in demobilization through co-optation or negotiating a …

Theism, Atheism, And Nagasawa’S “Problem Of Systemic Evil”, Jeremy Randel Koons

Faith and Philosophy: Journal of the Society of Christian Philosophers

No abstract provided.

Economic Background And The Role Of Self-Compassion, Dixy Melendez

Psychology and Counseling Theses

Although self-compassion is established as a buffer against psychological distress, few studies examine its protective role alongside socioeconomic discrimination. This study used hierarchical multiple regressions and a hierarchical logistic regression to examine subjective social status, downward classism, self-compassion, and internalized shame as predictors of distress, academic anxiety, and academic task choice among college students, controlling for demographic variables. Greater self-compassion predicted less internalized shame, and greater downward classism predicted greater shame and distress. Self-compassion showed only marginal protective effects against distress after accounting for other variables. Internalized shame was the strongest, most consistent predictor, robustly relating to academic anxiety and …

The Neuropsychological Analysis Of The Effect Of Shame And Traumatic Memories In Paranoia: A Network Analysis, Anwesha Maitra

Clinical Psychology Dissertations

Paranoia is increasingly recognized as a multidimensional psychological phenomenon influenced by trauma-related distress, shame, maladaptive interpersonal experiences, and emotional functioning. Although these factors have been extensively associated with paranoia, their relationships with neurocognitive functioning, social cognition, and global functioning remain less well understood. The present study examined these relationships using traditional statistical analyses, network analysis, and machine-learning approaches in a non-clinical sample of 42 adults.

Participants completed self-report measures assessing trauma-related distress, childhood interpersonal experiences, shame, paranoia, depressive symptoms, fear of negative evaluation, self-esteem, and hostile attribution bias, in addition to a comprehensive neurocognitive battery, an emotion recognition task, and …

Nicholas M. L. Nathan, A Map Of Selves: Beyond Philosophy Of Mind, Mark Textor

Faith and Philosophy: Journal of the Society of Christian Philosophers

No abstract provided.

Mosaic Loss Of Y Chromosome Associates With Lung Function, Emphysema, And Epigenetic Aging, Woei-Yuh Saw, Kangjin Kim, Yichen Huang, Jeong H Yun, Xiaolong Ma, Jason Bacon, Yash Pershad, Daniel Levy, George T O'Connor, Eric Boerwinkle, R Graham Barr, Stephen S Rich, Jerome I Rotter, April P Carson, Laura M Raffield, Sina A Gharib, Traci M Bartz, Bruce M Psaty, Tamar Sofer, Kari E North, Robert C Kaplan, Elizabeth C Oelsner, Ani Manichaikul, Alexander G Bick, Paul Scheet, Alexander P Reiner, Nhlbi Trans-Omics For Precision Medicine Consortium, Yasminka A Jakubek, Paul L Auer, Michael H Cho, Dawn L Demeo

Faculty, Staff and Student Publications

Rationale: As the global population ages, identifying risk factors for age-related diseases, such as COPD, is crucial for public health. Mosaic loss of Y chromosome (mLOY) in blood cells is an age-related somatic mosaicism event, but its relationship with pulmonary health remains undercharacterized.

Objectives: To examine the association between mLOY and pulmonary outcomes in men.

Methods: Leveraging mLOY assessment (cell fraction ≥ 5%) in over 12 000 men, including 5097 from the COPDGene Study and 7235 from six additional cohorts in the Trans-Omics for Precision Medicine program, we investigated mLOY associations with respiratory outcomes and epigenetic aging using multivariable cross-sectional, …

July 2026 Nh Ece Research Consortium Newsletter, Jess Carson, Evan England, Harshita Sarup

New Hampshire Early Care and Education Research Consortium

The July 2026 NH ECE Research Consortium Newsletter includes a link to the newly released statewide ECE research agenda. Also find the latest research publications, Consortium resources, upcoming events, opportunities, and more.

Current Adoption Of The Prosthodontic Diagnostic Index For Clinical Care-A Cross-Sectional Survey Study, Esther O Kuyinu, Joseph B Breitman, Arthur Nimmo, Jay S Patel

Faculty, Staff and Student Publications

Purpose: To assess current utilization of the Prosthodontic Diagnostic Index (PDI), identify perceived benefits and limitations, and evaluate support for future updates.

Materials and methods: A survey regarding the use of the PDI was made available through email invitations to 68 US dental school prosthodontic/restorative department chairs (PD), 48 graduate prosthodontic program directors (GP), and 1834 private practice prosthodontists (PP) from the American College of Prosthodontists (ACP) member database. The results of this initial survey were inconclusive due to low response rates. The survey was also administered during the 2024 ACP Annual Session with an improved response rate for educators. …

Kras G12c And Kras G12d Respond To Lipid Metabolism In An Allele-Specific Manner, Neha Arora, Hong Liang, Walaa Kattan, Wantong Yao, Haoqiang Ying, Junchen Liu, Yong Zhou

Faculty, Staff and Student Publications

KRAS mutated at hotspots G12, G13, and Q61 possess profound allele-specific oncogenesis. Signaling of KRAS mutants is mostly compartmentalized to the proteolipid nanoclusters on the plasma membrane (PM), illustrating critical roles of spatiotemporal organization in KRAS cancer signaling. The activated GTP-bound KRAS molecules, including the wild type and mutants, have been traditionally thought to favor similar lipids. We recently reported distinct lipid sensing capabilities of different KRAS mutants, especially with KRASG12D favoring unsaturated lipids and KRASG12C gaining additional enrichment of saturated lipids. As such, KRAS mutants may respond to lipid acyl chain remodeling in an allele-specific manner. Lysophosphatidylcholine acyltransferase 1 …

Quantitative Analysis Of Peri-Implant Collagen Fiber Orientation Around External Hexagon And Morse Taper Implant Connections: A Dog Model Study, Daniel Sartorelli Marques De Castro, Jefferson David Melo De Matos, Jozely Francisca Mello Lima, Maria Angelica Rehder De Araujo, Mário Alexandre Coelho Sinhoreti, Daher Antonio Queiroz, Adriano Piattelli, Carlos Dos Reis Pereira De Araújo

Faculty, Staff and Student Publications

Background: Peri-implant soft tissue stability depends on the implant-abutment interface and collagen fiber organization. Unlike natural teeth, peri-implant fibers exhibit a less favorable orientation, potentially weakening the biological seal. Implant connection design may influence this collagen arrangement and tissue integrity.

Materials and methods: Eighteen immediately loaded implants (n = 9 per group) were placed in nine mongrel dogs. Group I received external hexagon implants, while Group II received Morse taper implants. After a 4-month healing period, animals were euthanized and specimens were processed for histological evaluation. Collagen fiber orientation was analyzed using polarized light microscopy and quantified with ImageJ software. …

Erk-Mediated Phosphorylation Of Yap Defines A Noncanonical Fgf Signaling Mechanism In Stem Cells, Xiaolei Zhao, Shannon Erhardt, Li Tang, Xiaotong Chen, Stephen M Farmer, Zixiu Cheng, Wen Chen, Ella Ziyuan Lu, Kihan Sung, Chang-Ru Tsai, Mingjie Zheng, Sheng Zhang, Yang Liu, Jianxin Wang, Min Li, James F Martin, Jun Wang

Faculty, Staff and Student Publications

While Fgf and Hippo-Yap signaling are fundamental for proper development, homeostasis, and disease, their crosstalk remains largely unknown. Here, we identified that Yap and Taz, canonical Hippo effectors, function as noncanonical effectors of Fgf signaling to maintain the proper function of neural crest (NC) lineages. NC cells are a multipotent stem cell population during vertebrate embryogenesis that contribute to numerous structures and diverse cell lineages, including craniofacial and cardiac tissues, neurons, and suture mesenchymal cells (SMCs), a specified cell population required for cranial bone growth and repair. We observed that activation of Fgf signaling in NC cells and NC-derived SMCs …

Automated Machine Learning And Satellite Image Data Fusion For Monitoring Water Quality In Mosaicked Landscapes, Sahar Rezaei

Graduate Theses and Dissertations

Despite the ecological, economic, and social importance of inland water bodies, they are increasingly impacted by human and natural drivers. Harmful algal blooms (HABs) and total suspended solids (TSS) are key indicators of water quality, and elevated concentrations pose significant ecological and public health risks. The spatiotemporal dynamics of these variables remain insufficiently understood in major river systems, including the Upper Mississippi River (UMR) and the Illinois River Basin (IRB). While in situ measurements provide accurate observations, they are costly and offer limited spatial and temporal coverage, restricting basin-scale monitoring. Remote sensing offers a powerful alternative; however, single-sensor approaches are …

His 127 Microhistories: A Lens Into The Past — Apartheid In South Africa Syllabus, Marta Millar

Open Educational Resources

The microhistory course introduces students to the study of history by exploring a particular event, individual, or issue, and its legacy. Students will read both primary source documents and modern texts to examine how the topic under consideration was shaped by, and in turn shaped contemporary culture.

This syllabus is for a course focusing on the history of apartheid in South Africa. Students will analyze the political, social, economic, and cultural aspects of the apartheid era. This includes understanding how segregationist policies developed in South Africa, what political transformations led to the implementation of the apartheid system, how different policies …

Priyanka Goonetilleke, Priyanka Goonetilleke

Faculty CVs

No abstract provided.

Felix Mormann, Felix Mormann

Faculty CVs

No abstract provided.

Locally Robust Implementation Of Efficient Bilateral Trade With Correlated Beliefs, Takashi Kunimoto, Cuiling Zhang

Research Collection School Of Economics

We identify the ex ante welfare (EAW) condition as a necessary requirement to implement ex post efficient bilateral trade in any finite type space with interdependent values and correlated beliefs. As these finite settings become finer to approximate a continuous type space, we derive a limit EAW condition by taking the EAW condition in finite settings to its limit. We show that this limit condition trivially holds in the benchmark continuous setting admitting a full-support density function. We then insist on locally robust implementation by requiring efficient trade to be implemented uniformly across all finite type spaces that approximate the …

Occupation Ladders Over The Business Cycle, Ismail Baydur, Toshihiko Mukoyama

Research Collection School Of Economics

This paper studies occupational mobility over the business cycle. We divide occupations into two broad groups, “attractive” and “nonattractive”, where we label an occupation attractive if the total net inflow into this occupation through job-to-job transition is positive. We measure total net inflows into both occupation groups. We measure these inflows separately for job-to-job transitions and transitions from unemployment to employment. We find that the net inflow from nonattractive to attractive occupations through job-to-job transitions slows during recessions. The net inflow through transitions from unemployment has a similar cyclicality. This finding suggests a novel cost of recession: during recessions, workers …

Sustainable Rural Development Under Ecological Civilization: Two Mountains Theory, “Green Rural Revival”, And Post-Productivist Transition In Zhejiang, Qian Forrest Zhang, Jianzhang Luo, Li Zhou

Research Collection School of Social Sciences

Existing studies of China’s overarching ideological framework for national development, “Ecological Civilization”, have focused narrowly on environmental governance; how it reshapes sustainable rural development remains underexplored. This paper pursues two analytically distinct tasks. First, it reconstructs the policy history of how President Xi Jinping’s “Two Mountains” theory was incorporated into the Eco-civilization framework and how Zhejiang Province’s “Green Rural Revival” (GRR) program, as a lived example of Eco-civilization, was elevated as the national template for rural development in 2024. Second, drawing on three cases from a sample of 21 villages in Zhejiang, it identifies three core practices of GRR and …