Digital Commons Network^™

Role Of The Small Intestinal Microbiota In The Pathogenesis Of Environmental Enteric Dysfunction In Undernourished Children And Mothers, Clara Kao

Arts & Sciences Graduate Student Theses and Dissertations

Undernutrition in women and its propagation in their children remains a major global health challenge. Worldwide, one in five children under five years of age manifests undernutrition as impaired linear growth, or stunting. Stunting, defined as having a length-for-age z-score (LAZ) <-2, is associated with poor developmental outcomes, including impaired neurodevelopment and immune responses. Furthermore, stunting and its long-term sequelae persist across generations, contributing to an intergenerational cycle of undernutrition. Existing nutritional interventions fail to substantially improve stunting, highlighting the need to (i) better understand other factors contributing to stunting and (ii) focus clinical efforts towards treating maternal undernutrition. Environmental enteric dysfunction (EED) is a subclinical inflammatory enteropathy of the small intestine proposed to contribute to stunting. EED is diagnosed histologically by blunted intestinal villi, epithelial barrier disruption and an immunoinflammatory infiltrate in the lamina propria. However, the pathophysiology of EED remains poorly defined. Furthermore, the small intestinal microbiota remains understudied due to difficulties in sampling. Evidence that the small intestinal microbiota contributes to EED pathogenesis comes in part from our collaborative work with colleagues at icddr,b (the International Centre for Diarrhoeal Disease Research, Bangladesh) who oversaw the Bangladesh EED (BEED) study. In this study children, aged 12-18 months residing in an urban slum in the Mirpur district of Dhaka who failed a nutritional intervention for their stunting, underwent esophago-gastroduodenoscopy (EGD) to obtain duodenal mucosal biopsies, aspirates of duodenal luminal fluid and plasma samples. A set of 14 bacteria taxa (defined by 16S rRNA amplicon sequencing) were identified in the duodenal microbiota of >80% of children with EED. Moreover, the absolute abundances of these ‘core taxa’ were positively correlated with duodenal mucosal and systemic inflammation in study participants and negatively correlated with linear growth. Our lab showed that introduction of a consortium of bacteria cultured from these duodenal aspirates, including these core taxa, produced small intestinal inflammation in young adult gnotobiotic, providing …

“Take This Job And Shove It”: How Black Women’S Fight For Economic Rights Informed Their Participation In The Broader Social Movements Of The Twentieth Century, Kyndle Diane Lee

Honors Theses

This thesis examines the vital role of Black women in the American labor movement during the twentieth century, emphasizing how their leadership and union participation were central to both labor organizing and the broader fight for human rights. Black women workers navigated and resisted the effects of racism, sexism, and class exploitation in a century marked by industrial expansion, economic upheaval, and major civil rights struggles. Far from passive participants, they emerged as key organizers, negotiators, and strategists in their communities, labor unions, and national movements. Additionally, their work extended beyond their demands for better wages and safer working conditions. …

Elemental Humanity: A Hybrid Collection Of Creative Work & A Critical Introduction Exploring Relevant Genres & Themes, Haylee G. Morman

Honors Theses

This project is a creative and critical endeavor with two components: a creative portion and a critical introduction. The creative portion is a hybrid collection of poems and short prose spanning across genres and forms, linked by thematic consistencies, united by their emphasis on nature and family. Furthermore, the collection is rooted in my interest in magic realism and ekphrasis, which will be discussed in the critical introduction. The approximately 30 pages of original, creative writing reveals how delving into natural elements for inspiration spurred the creation of poems and stories that grapple with notions of familial connection, time, place, …

Entanglement-Enhanced Metrology With Superconducting Circuits, Xingrui Song

Arts & Sciences Graduate Student Theses and Dissertations

Circuit quantum electrodynamics provides a unique platform for investigating fundamental physics and practical quantum applications. In this thesis, I introduce the superconducting circuit platform from a foundational perspective. Drawing inspiration from quantum electrodynamics and utilizing the analog of closed time-like curves, this work achieves quantum enhancement over classical strategies. Specifically, I investigate agnostic phase estimation protocol and the associated approaches that leverage quantum entanglement to optimally estimate an unknown rotation angle without requiring prior knowledge of the rotation axis. This work not only demonstrates a proof of concept for a type of entanglement-assisted metrology but also highlights intriguing quantum effects. …

Reimagining Heroes: The Evolving Narratives Of Helen And Achilles In Feminist Greek Mythology Retellings, Elena A. Smith

Honors Scholar Theses

“Reimagining Heroes: The Evolving Narratives of Helen and Achilles in Feminist Greek Mythology Retellings” is an analysis of an array of novels, monographs, and critiques regarding the genre of mythology retellings. Combining feminist ideas with historical examples, this thesis delves into why retellings are so popular in the twenty-first century and why the stories of Greek Antiquity have stayed relevant.

This thesis focuses specifically on Helen of Troy, Achilles, and the events of the Trojan War in The Iliad. Comparing the epic with retellings of its events may reveal why these characters, gods, and heroes have continued to be discussed …

Parsing Heterogeneity In Depression, Kayla Hannon

Arts & Sciences Graduate Student Theses and Dissertations

Depression is a highly prevalent mental health disorder that often requires treatment. While current treatments are effective for a large portion of patients generally, the exact medication that works for any specific person is unclear, leading to large delays in symptom remittance if at all. This hurdle has motivated substantial efforts to identify markers of depression that might predict treatment outcomes. However, large sources of heterogeneity in depression have stymied progress on identifying robust and replicable neuroimaging markers. Parsing this heterogeneity is crucial but mired with challenges. My dissertation work has elucidated several key barriers in parsing the heterogeneity of …

Effects Of Surprisal And Prediction Uncertainty On Detailed And Gist Aspects Of Memory, Thanh Tan Nguyen

Arts & Sciences Graduate Student Theses and Dissertations

Schemas guide comprehension and memory of everyday activities, yet theories differ on how schema‐unexpected or schema‐expected events affect memory. In this study, we compared predictions from the Schema‐Linked Interactions between Medial Prefrontal Cortex and Medial Temporal Lobe (SLIMM) model, which proposes a U‐shaped function for gist memory (both highly expected and highly unexpected events are well remembered) and a linear function for detailed memory, with those of the Schema Copy Plus Tag (SC+T) theory, which proposes a linear function for both gist and detailed memory. Participants read everyday activity narratives with events varying in surprisal, prediction uncertainty, and relevance to …

Building Character: How Stories Shape Our Children, Abby De Groot

Faculty Work Comprehensive List

"Stories can help us imagine ways to partner with God in His restorative Kingdom work and can help foster our love for virtue."

Posting about ­­­­­­­­how stories influence our thinking from In All Things, an online hub that offers insight into maintaining and faithful and orthodox Reformed Christian worldview while fearlessly engaging in every aspect of contemporary life – until all is made new.

Building Character: How Stories Shape Our Children

The Mujahedeen E-Khalq Of Iran (Mek): Agents Of Democratic Revolution Or Cultic Oppression?, Molly Jones

Electronic Theses and Dissertations

This thesis focuses on the People’s Mujahideen of Iran (MEK), an Iranian oppositional group that has engaged in a decades-long effort to depose the Iranian government. The goal of this thesis has three parts. First, it examines if the MEK should be classified as a new religious movement/cult. It also addresses the implications of such status given the MEK’s claims that it functions as a democratic entity and that it can be trusted to govern Iran in democratic fashion. Secondly, it examines if Iranian disinformation has influenced the MEK’s reputation. Thirdly, it analyses how the MEK has been able to …

The Role Of Elongin B In Drosophila Melanogaster Muscle Development, Madelyne Dayan

Student Theses and Dissertations

Muscle atrophy is a result of a number of muscle diseases, as well as aging, disuse, and infections. Muscles weakened in these ways exhibit a characteristic decrease in size, strength, and mobility. The similarities between muscle in humans and Drosophila allow for direct comparisons to be made in vertebrates from studying muscle in Drosophila. Differential gene expression has been shown to play an important role in embryonic muscle development in Drosophila melanogaster. A previous study identified Elongin B (EloB) to be involved in somatic muscle morphogenesis in Drosophila, with mutant embryos displaying severe muscle defects, including thin, mis-attached, and missing …

Shifting Alliances: Are Black People Increasingly Identifying As Republican?, Clamont C. Mack

Student Theses and Dissertations

This paper investigates claims that Black Americans are increasingly aligning with the Republican Party. Drawing on theories of party identification and political realignment, I compare competing perspectives to determine appropriate indicators of realignment within the Black community. Using quantitative analysis across several datasets, I find a modest rise in Republican identification over the past decade, but a more pronounced decline in Democratic affiliation. These findings suggest not a realignment toward the Republican Party, but rather a dealignment from the Democratic Party. This challenges popular media narratives of realignment and instead points to growing political disengagement among Black Americans.

Spills & Layers, Anastasya Peña

Theses and Dissertations

Spills & Layers explores how process can give a painting meaning. My work uses acrylic and oil paint to create compositions that are both visible (spilling across the canvas freely) and hidden (caught under layers of paint).

Found Words, Lost Homes: Immigration And The Language Of Identity, Ali Motamedi

Theses and Dissertations

This thesis explores the relationship between personal experience and public space through a body of work that moves between image, text, and material. Rooted in an intimate perspective and extending into streets, landscapes, and communal environments, the practice examines how nomadism—both physical and conceptual—shapes ways of seeing and making. Drawing from my background in engineering, a deep connection to Farsi literature, and the lived experience of immigration, the work reflects on themes of displacement, belonging, and identity.

To Protect The Sky From Falling, Charles Lambert

Theses and Dissertations

Using ceramic, found objects, metal and wood, my practice is a meditation and questioning of care, efficiency, repair, structure and place. Architectural elements of support rendered in clay are the initial point of entry to give a soft, lived-in quality to a built environment that is often devoid of the mark of the hand and body. Imprints of the hand are left, and the objects are often deformed in ways to subvert the perceived functionality. The focus on ceramics centers around a play with the binary of soft and hard and the external changes that create its transformation. The work …

A Limit That Recedes, Chloe Wilcox

Theses and Dissertations

In "A Limit that Recedes", I discuss my art practice in terms of accumulation and techniques of reproduction, such as casting, printing, and repetitive actions. I contextualize my work among artists such as H.C. Westermann, Isa Genzken, and Paul Thek. The work featured in this thesis explores ideas of aspiration, longing, and failure, and explores themes of the fraught relationship of the human and nature.

The Influence Of Money In Politics, Aminata Dieng

Undergraduate Research Symposium Podium Presentations

Money plays a powerful role in shaping political outcomes by significantly influencing who gets elected and which policies are prioritized. Campaign financing, which includes donations from individuals, corporations, and Political Action Committees (PACs), often determines a candidate's visibility, resources, and ability to compete effectively. Those with greater financial backing tend to dominate media coverage and reach more voters, which can tip the scales in elections.

Divided Attention With Long-Term Memory: Recollection And Familiarity For Musical Melodies, Gaia Steinberg, Jackson S. Pelzner, Rhiannon N. Soriano Smith

Undergraduate Research Symposium Posters

Objective: Test whether the well-established effects of divided attention 1, 2. (DA) found with non-musical (i.e., verbal and pictorial) materials generalized to musical melodies.

Background: Few studies have used melodies to test recognition models (e.g., DPSD). Parks et al.2 showed stimulus complexity alters source memory reliance on recollection (R) and familiarity (F).

Method: Used a 2 (attention) x 2 (melody type) mixed design with an old-new recognition test to compare DA effects across well-known and novel melodies.

Experiment 1: Applied an n-back task to split participants’ attention; no significant DA effect was observed.

Experiment 2: Shortened melody length and added …

Quality Improvement Project Impact Of Multidisciplinary Patient Education On Heart Failure 30-Day Readmission Rate, Jeanne P. Williams

Doctor of Nursing Practice Projects

Patients diagnosed with heart failure are at an increased risk for readmission to the hospital within 30 days of discharge, and their care costs are projected to continue to increase. This Doctor of Nursing Practice (DNP) quality improvement (QI) project aimed to implement an evidence-based initiative to mitigate the increased heart failure 30-day readmission rate on a 30-bed medical-surgical telemetry unit in an acute care facility. Using the teach-back communication method, multidisciplinary patient education was implemented to prepare patients diagnosed with heart failure to manage their condition once discharged home. The theoretical and implementation frameworks used were Lewin’s Change Model, …

Entry-Level Physical Therapists’ Perceptions Of Initial Employment, Richard G. Hubler Jr.

Seton Hall University Dissertations and Theses (ETDs)

As physical therapy (PT) grows as an autonomous profession within the ever-changing healthcare system of the United States, PT educators strive to provide students all the training that they require for a career in professional clinical practice. Although graduates of PT education programs receive a doctoral degree, their preparedness to succeed in their early career is unclear. The purpose of this qualitative research study is to investigate the perceptions of entry-level physical therapists (PTs) toward early professional practice and their initial employment choices. Entry-level PTs that have been employed full-time for one year or less were interviewed to gain an …

Joe Biden Victory In The 2020 United States Presidential Election: Literature Review, Amril Hanif Zaki

Jurnal Wacana Politik

The impact of the COVID-19 pandemic on the 2020 US presidential election is worth watching. Also, who wins the US presidential election will influence US foreign and international policy. This research aims to examine the 2020 US Presidential Election, focusing on Joe Biden’s victory. The author uses Scopus sources, which are analyzed using VOS viewer, NVivo, SWOT, Literature Review, and political communication theory, resulting in the peak of Joe Biden’s research in Scopus in 2023 experiencing a decline. The author also finds the involvement of Russian researchers who analyze Joe Biden, where these two countries have been rivals for a …

Dexmedetomidine As An Adjunct To Local Anesthetics In Neuraxial Anesthesia: A Scoping Review, Meaghan Elrod, Jacob Flake, Sarah Eggers, Kieraney Coston, Dwayne Accardo Dnp, Crna, Faana

Doctor of Nursing Practice Projects

Purpose/Background

Neuraxial anesthesia is key for pain management and comfort during surgery. While local anesthetics and opioids have notable side effects, Dexmedetomidine (DEX) offers a promising alternative. Early studies suggest DEX improves pain control, prolongs anesthesia duration, and reduces opioid-related side effects. This review explores the benefits of incorporating DEX into neuraxial anesthesia for better patient safety and comfort

Methods

This scoping literature review took place from August 2023 to April 2024, utilizing PubMed, CINAHL, Cochrane Library, and Google Scholar for sources. After reviewing over 2,000 abstracts, 25 articles met the inclusion criteria, with nine selected as most relevant. Four …

Editorial–Special Issue On Application Of Cold Atmospheric Plasma In Human And Veterinary Disease, Katharina Stapelmann, Eloisa Sardella, Vandana Miller

Kimmel Cancer Center Papers, Presentations, and Grand Rounds

Plasma medicine is a rapidly evolving interdisciplinary field that combines plasma science and engineering, chemistry, biology, and medicine. This special issue focuses on various ways to apply cold atmospheric pressure plasma in translating plasma technology into clinical applications. Ongoing research on the redox-based mechanism of plasma action, the concept of 'plasma dose' and device control is critical for advancing plasma medicine. As these applications move toward the clinic, ensuring the reproducibility and quality control of plasma sources is essential. The articles in this issue present examples of both direct and indirect plasma applications, with indirect treatments describing cell exposure to …

Know Thyself: A History Of Ancient Neuroscience, Alex Delano

Departmental Honors & Graduate Capstone Projects

Neuroscience is often described as one of the youngest bodies of science, but documented study of the brain begins as early as the Neolithic period. The ancient Mediterranean was a hub for science, mathematics, philosophy, and literature, all disciplines necessary for the study of the brain. Evidence of neurosurgical procedures like trepanation and craniotomy began in the Neolithic period and were practiced and improved upon throughout the ancient Mediterranean. The first detailed studies on brain anatomy were carried out in the 3^rd century BCE in Greece which created a necessary structure for future scientists to build on. While many …

Gender Within 20th Century Lesbian Literature, Margaret A. Paulson

Departmental Honors & Graduate Capstone Projects

This paper examines gender identities within what is historically categorized as lesbian literature, focusing from 1928 to 1993. In The Well of Loneliness by Radclyffe Hall, Orlando by Virginia Woolf, Nightwood by Djuna Barnes, and Stone Butch Blues by Leslie Feinberg, gender is portrayed in complex ways. In The Well of Loneliness, Stephen is labeled as an invert and often viewed as a masculine lesbian, but she also states that she loves women like a man loves women. For Orlando, the character of Orlando goes through a sex change and transitions from a man to a woman for Woolf to …

Storytelling Or Telling Stories: An Analysis Of Disnarration In Music Videos, Victoria Garrett

Honors Theses

Music videos have grown in popularity in recent years and have begun to augment the stories being told by the lyrics of their songs. This is done by using narrative techniques, such as disnarration, to develop complex narratives that can conflict with the lyrical content. Through analysis of the videos "Willow" (2020 dir. Taylor Swift) by Taylor Swift, "The One That Got Away" (2012 dir. Floria Sigismoni) by Katy Perry, and "One Beer" (2020 dir. Justin Clough) by HARDY, the distinction between the plots of the videos and the lyrics can be brought into focus. This distinction in the stories …

Competence Protein Comea And Oxidative Stress In Bacillus Subtilis Stationary Phase Mutagenesis, Angeline Roldan, Sam Schauf

Undergraduate Research Symposium Posters

Stationary Phase Mutagenesis is a process where a bacterium can accumulate mutations in the absence of cell division. This may occur via competent DNA uptake and oxidant DNA damage and repair. ComEA is a transmembrane protein in B. subtilis that is required for the transport of exogenous DNA into the cell. (Figure 1)

The Importance Of Being Earnest: A Costume Designer’S Process, James Hunter Rock

Johnny Carson School of Theatre and Film: Theses, Student Research, and Creative Work

This thesis is a comprehensive breakdown of the costume design process for Nebraska Repertory Theatre’s production of The Importance of Being Earnest by Oscar Wilde during the fall semester of 2024. The author logs the production’s processes in collaborating on the concept and aesthetic of the play to present the Victorian era story for a modern audience. In this thesis, insights into the costume designer’s conceptualization, research, previsualization, and final design process are explored, providing an in-depth look into the creation of characters that remain true to the director’s original vision while being engaging for contemporary theatre. The various challenges …

Pharmacist-Led Statin Initiation In Adults With Diabetes At An Adult Internal Medicine Clinic, Kevin Le, Michael Takach, Linh Gagnon, Dylan Atchley

Costas T. Lambrew Research Retreat 2025

Purpose: Implement and evaluate a pharmacist-led program addressing the current underutilization of statins among these high-risk patients with diabetes

Factors Influencing No Show Rates In Adult Urology Patients, Bruce T. Ndebanje, Ethan Griffin, Evelyn James, Lily C. Wang

Costas T. Lambrew Research Retreat 2025

Our study highlights a strong association between insurance status and no-show rates. Patients with Medicaid or no insurance were significantly more likely to miss appointments (OR 3.25 and 5.99).

Pediatric Asthma Subspecialty Referral Practices In Rural Maine, Paras Patnaik, John Dipalazzo, James Bohnhoff

Costas T. Lambrew Research Retreat 2025

Over 7.2 million children in the United States have asthma.

• >300,000 asthma-related ED visits & hospitalizations yearly
• Both PCP’s and pediatric asthma subspecialists (allergist/immunologists and pediatric pulmonologists) provide long-term asthma care