Digital Commons Network^™

Experiences Of Occupational Engagement In Young & Middle-Aged Women Post-Stroke: A Qualitative Systematic Review, Li Kiang Regina Toh, Tanja Križaj

School of Health Professions

Purpose: Young and middle-aged women engage in distinct occupations, facing unique post-stroke challenges that complicate their recovery. However, little is known about their experiences with occupational engagement following a stroke. This qualitative systematic review aimed to explore the post-stroke experiences of women aged 18–65 from an occupational perspective of health. Methods: A comprehensive search of five databases identified qualitative studies on post-stroke experiences of women aged 18–65. Two reviewers independently appraised the methodological quality of eligible studies. Data were extracted and synthesised using the Joanna Briggs Institute (JBI) method of meta-aggregation. Results: Seven studies were included. From 103 extracted findings, …

The Clinical Characteristics, Correlation With Other Disorders, And Treatment Methods For Children And Adolescents With Body-Focused Repetitive Behaviors, Paige Gunther

Student Works

Body-focused repetitive behaviors (BFRBs) are repeated actions performed on oneself as acts of self-grooming that may result in self-harm. The most common BFRBs are nail biting, excoriation (skin picking disorder), and trichotillomania (hair pulling disorder). This literature review examines the clinical characteristics, correlation with other psychological and neurological disorders, and treatment options for various BFRBs. A search of APA PsycInfo and PubMed databases yielded 74 sources, 13 of which have been used in this review. Clinical characteristics of BFRBs include emergence during childhood and adolescence, influence of other psychological disorders, self-awareness, biological sex, internalizing and externalizing behaviors, high levels of …

Global Mitophagy Inhibition Via Bnip3 Ablation Is Not Sufficient To Alleviate Skeletal Muscle Impairments In Male And Female Tumor-Bearing Mice, Francielly Morena, Ana Regina Cabrera, Toby L. Chambers, Pietier J. Koopmans, Seongkyun Lim, Stavroula Tsitanou, Sabin Khadgi, Calvin Peterson, Eleanor R. Schrems, Ruqaiza Muhyudin, Sepideh Shakeri, Kevin Zhao, Devan Mishra, Tyrone Washington, Kevin A. Murach, Nicholas P. Greene

Health, Human Performance and Recreation Faculty Publications and Presentations

Cancer cachexia (CC) is marked by severe skeletal muscle loss and dysfunction, associated with mitochondrial degeneration. Our previous studies showed induction of the mitophagy marker BNIP3 3-wk post-Lewis lung carcinoma (LLC) induction. We hypothesize that excessive mitophagy contributes to muscle wasting in CC. To test this, we used a Bnip3 knockout (KO) mouse model with LLC-induced CC to assess its impact on muscle outcomes. Eight-wk-old male and female mice were injected with 1 x 10(6) LLC cells or PBS (sham controls). After 4 wk, we assessed muscle function through dorsiflexor electrophysiology, muscle protein synthesis via deuterium oxide labeling, and mitochondrial …

Nutrient Dynamics In Restored And Unrestored Urban Streams In The Piedmont Ecoregion Of South Carolina, Emily J. Jordan, Debabrata Sahoo, Calvin B. Sawyer, Jeremy W. Pike, Dara M. Park, Sarah A. White, Brian E. Haggard

Biological and Agricultural Engineering Faculty Publications and Presentations

The United States invests billions of dollars annually to perform stream restoration projects, yet few studies have investigated the effects this ecosystem manipulation has on nutrient cycling and associated water quality. Water quality improvement remains a substantial motivation for mitigating catchment-scale disturbances, especially in urban streams. Various urban land use practices impact the transfer and transport of nutrients such as soluble reactive phosphorus, ammonium, and nitrate plus nitrite from land into the streams and rivers. The uptake length (Sw), or the distance a dissolved nutrient travels downstream within a stream reach, can be measured using short-term nutrient injections, where shorter …

Closing The Gap: Reevaluating Cafe Standards And The Light Truck Loophole, Benton Marcotte

LSU Journal of Energy Law and Resources

No abstract provided.

Perceived Neighborhood Crime And Gun Carrying Behavior: Examining The Role Of A History Of Traumatic Brain Injury, Eric J Connolly, Anne C Wingert, Dennis E Reidy, Jarrad D Hodge, Jeff R Temple

Faculty, Staff and Student Publications

Background: Individuals living in high crime neighborhoods are more likely to carry a firearm. Members of these communities are also more likely to experience a traumatic brain injury (TBI) in their lifetime, which is a common correlate of hypervigilance and aggression. The current study evaluates the independent and interactive effects of TBI on perceived levels of neighborhood crime and gun carrying.

Methods: Data from 2015 to 2017 from a longitudinal ethnically diverse sample of adolescents and young adults are analyzed (Ns = 600-734). Multivariate logistic regression models are estimated to evaluate associations between perceived levels of neighborhood crime, TBI, gun …

Exploring The Relationship Between Burnout, Professional Fulfillment, And Individual And Organizational Factors In Nurse Managers Across Ambulatory And Inpatient Settings, Yulia Romazanova Lopez

MUSC Theses and Dissertations

Nurse managers play a vital role in the functioning and stability of healthcare systems, yet their well-being remains an underexplored area of research. The COVID-19 pandemic brought renewed attention to occupational burnout, including in nursing leadership, where nurse managers reported high levels of stress, emotional exhaustion, and organizational strain. While the literature on burnout has grown rapidly in recent years, there is limited research that addresses what comes next, what sustains nurse managers in their roles and how organizations might foster their long-term well-being and engagement. This dissertation compendium explores professional fulfillment (PF) as a proactive and constructive lens for …

Association Between Dietary Inflammatory And Antioxidant Potential And Systemic Inflammatory And Oxidative Status With The Risk And Severity Of Coronary Artery Disease, Zahara Namkhah, Elham Alipoor, Manhnaz Salmani, Negar Ebrahimi, Monireh Ahmadpanahi, Ali Vasheghani-Farahani, Mehdi Yaseri, Michael David Wirth, Longgang Zhao, James Hébert Scd, Javad Hosseinzadeh-Attar

Faculty Publications

Background and aims

Unhealthy diets have pro-inflammatory properties that have been shown to contribute to coronary artery disease (CAD). The dietary inflammatory index (DII®) and the dietary antioxidant quality score (DAQS) quantify the anti-/pro-inflammatory and antioxidant potential of a diet. This study aims to investigate the association between the energy-adjusted DII (E-DIITM), DAQS, oxidant/anti-oxidant biomarkers, and CAD risk and severity.

Methods and results

This cross-sectional study investigated 158 participants for the presence and severity of CAD based on coronary angiography. E-DII and DAQS scores, malondialdehyde (MDA), total oxidant status (TOS), glutathione peroxidase (GPX) activity, total antioxidant capacity (TAC) and conventional …

Coming Soon To A State Near You? Does Louisiana’S Public Trust Doctrine Encompass A Right To A “Clean And Healthful Environment?”, Ryan M. Seidemann

LSU Journal of Energy Law and Resources

No abstract provided.

What Is A Mineral In The Green Energy Age?, Jonathan J. Rose

LSU Journal of Energy Law and Resources

No abstract provided.

Getting An Airman Medical Certificate With Cerebral Palsy, Stefan Crisp

Honors Theses

This paper aims to document the personal experience of Stefan Crisp attempting to gain an airman medical certificate. It also aims to expose the airman medical certificate process for people with cerebral palsy in the United States. Stefan Crisp, who has cerebral palsy, attempted to gain an airman medical certificate through three attempts across multiple years. Research was done to compare the United States Federal Aviation Administration (FAA) with the United Kingdom's Civil Aviation Authority (CAA) to reveal similarities and differences between accessibility and requirements. Despite successfully navigating through Title 14 Code of Federal Regulations Part 67, Stefan was unable …

Complementarities In High School And College Investments, John Eric Humphries, Juanna Schrøter Joensen, Gregory Veramendi

Cowles Foundation Discussion Papers

This paper examines how high school specialization shapes college investment decisions and their subsequent returns through dynamic complementarities. Using Swedish administrative data, we estimate a dynamic Roy model that accounts for selection on multidimensional skills, family background, prior investments, and unobserved heterogeneity. We identify the model using rich skill measures and quasi-experimental variation in program popularity. For marginal students, STEM specialization in high school increases wages by 9%, with more than half this return attributed to dynamic complementarities that enhance the productivity of subsequent college investments. Consequently, we find that counterfactual policies encouraging high school STEM specialization generate twice the …

Cardiovascular Health In Cardiac Rehabilitation: Applying The American Heart Association Life's Simple 7 Framework In A Center-Based Cohort, Audry Chacin-Suarez, Tomoaki Hama, Matthew P. Johnson, Helayna Abraham, Thomas P. Olson, Laprincess C. Brewer

Einstein Health Papers

BACKGROUND: Cardiac rehabilitation (CR) is a comprehensive secondary cardiovascular disease program with structured lifestyle interventions to reduce morbidity and mortality. The American Heart Association cardiovascular health (CVH) framework measures health-promoting behaviors and clinical factors, but it has not been rigorously evaluated in the CR setting.

METHODS: This retrospective cohort study analyzed patients attending CR from January 2018 to September 2020. Patients were evaluated at baseline (pre-CR) and completion (post-CR) using 3 clinical factors (blood pressure, cholesterol, and hemoglobin A1c) and 4 health behaviors (smoking, body mass index, physical activity, and diet). CVH score was computed as a composite of each …

Harboring Change: Legacy Contamination, Plant-Metal Dynamics, And The Fate Of A Boston Marsh, Emma Brooks

Graduate Masters Theses

Coastal wetlands within the Boston Harbor watershed provide numerous ecosystem services and community benefits but are challenged by anthropogenic influence including a legacy of pollution and increasing mean sea level. In this thesis, I will consider the historic and present sources of contamination in Boston Harbor, the role an individual salt marsh species (Salicornia depressa) plays in the movement of heavy metals, and how projected sea level rise and urbanization may affect future marsh viability. These complex issues are explored through a case study of Pattens Cove, a 9.6-acre parcel of state-managed land in Dorchester, MA home to …

Our Common Cause: Advocating For Human Labor For Outreach, Technical Expertise, And The Future Of Institutional Repositories, Grace R. Swinnerton, Dylan Mohr

Librarian Publications

Since 2021, SURFACE, Syracuse University’s institutional repository, has seen substantial growth in both content and commitment to long-term digital preservation. This progress is largely due to the Syracuse University Libraries’ investment in a dedicated three-person team focused on sustainability and development. As we face emerging technologies and AI, we question whether AI can replace human labor to reduce costs. Despite the financial appeal of cost-cutting, our presentation underscores the essential role of human labor. Through community-focused outreach and technical advancements like mass minting DOIs and restructuring our platform, we have demonstrated the irreplaceable value of human involvement. This presentation will …

Potential Epigenetic Impacts Of Phytochemicals On Ruminant Health And Production: Connecting Lines Of Evidence, Sebastian P. Schreiber, Juan Villalba, Mirella L. Meyer-Ficca

Wildland Resources Student Research

The once mysterious “dark matter of nutrition”, comprising countless plant derived secondary compounds, also known as phytochemicals, is now understood to have significant and wide-ranging effects on consumers, including myriad health benefits in humans and livestock. The selective consumption of phytochemically rich and diverse plants, in appropriate doses, by ruminants represents an adaptive means of therapeutic and prophylactic self-medication. Due to their chemical structure, phytochemicals have long been recognized as antioxidants. However, the mechanisms that underlie numerous additional phytochemical-based health benefits are generally less understood. These effects (i.e., anti-inflammatory, immunomodulatory, and anticarcinogenic effects) are likely related to epigenetic processes. Evidence …

Slow-Growing Lung Mass In A Patient With Multiple Endocrine Neoplasia Type I: Consider Carcinoid Tumor, Ramin Talebi, Charalambos C. Solomides, Nathaniel R. Evans Iii, Gregory C. Kane

Division of Pulmonary, Allergy, and Critical Care Medicine Faculty Papers

A 23-year-old man with multiple endocrine neoplasia type 1 (MEN 1) with pancreatic tail masses and Cushing syndrome (status after transsphenoidal adenomectomy) presented with a slow-growing, asymptomatic right lower lung lobe mass confirmed to be an atypical carcinoid tumor by pathologic staging following successful basilar segmentectomy with mediastinal lymphadenectomy. Pulmonary carcinoid tumor (PCT) is a rare neoplasm in patients with MEN 1, but there is limited data on trends in atypical versus typical carcinoid tumors in these patients. This case emphasizes the need to characterize these trends given the implications for metastatic potential and 5-year survival, which can help guide …

A Systematic Evaluation Of Threaded Internode Communication In Hpc, William Pepper Marts

Computer Science ETDs

High Performance Computing (HPC) applications increasingly rely on both process and thread-level parallelism to maximize performance across complex, multi-node systems. However, conventional bulk synchronous communication strategies often leave both compute and network resources underutilized due to synchronization delays. This dissertation systematically evaluates the potential of fine-grained, threaded inter-node communication as a strategy for reducing these inefficiencies. To this end, I design and develop two tools: the MiniMod modular application framework and the Configurable Messaging Benchmark (CMB), which together enable empirical, reproducible assessment of communication performance across varying application behaviors, threading models, and communication granularities. Through experiments across multiple systems and …

Topic Shift Detection And Triggering In Natural Dialogue Systems: A Lightweight Approach, Rohith Perumandla

College of Computing and Digital Media Dissertations

This research address a key challenge in dialogue system: enabling the proactive, human-like shifting using lightweight approaching using MobileBERT (~25M) model was proposed and fine-tuned for topic shift detection, augmented with liguistic featuers for for topic trigger detection. Despite its smaller size (~25M parameters), the MobileBERT-based system achieved competitive results (F1 = 74.16%,) compared to the much larger XLNet model (~110M parameters, F1 = 79.95%), while offering greater efficiency. The topic trigger module, combining MobileBERT with linguistic features, further demonstrated effective performance (F1 = 71.61%).

“There Is Nothing”—Exploring Diagnostic And Service Access For Autistic Individuals In Uruguay: A Qualitative Study, Maria Montenegro, Gabriela Garrido, Leyla Feize, Liza Talavera-Garza, Bianca T. Villalobos, Cecilia Montiel-Nava

Psychological Science Faculty Publications

Due to the higher autism research presence of higher-income countries, the known social and cultural experiences of families raising a child with autism are centered on their realities. This narrative overlooks the experiences of many families who do not fit this archetype, such as those residing in low- and middle-income countries, who are particularly challenged by the limited availability of trained professionals and barriers to accessing diagnosis and evidence-based treatments. That is the case in Latin American countries, such as Uruguay, where the present project transpires. By utilizing a Theory of Change framework, specifically developed to be used in low- …

Education Improves Perceived Control But Not Risk Identification In Adolescents Regarding Fentanyl, Christine Bakos-Block, Francine R Vega, Marylou Cardenas-Turanzas, Bhanumathi Gopal, Tiffany Champagne-Langabeer

Faculty, Staff and Student Publications

Background/objectives: In 2022, 2.2 million adolescents were diagnosed with substance use disorders, including 265,000 with opioid use disorder. The National Survey on Drug Use and Health revealed that 130,000 adolescents misused prescription pain medications, often obtaining them from friends or relatives. This age group perceives weekly heroin use as less risky than those younger or older.

Methods: A questionnaire was developed for 7th to 12th graders in a rural Texas school district as part of a fentanyl awareness curriculum. The questionnaire included Likert scale, multiple choice, and yes/no questions. The participants were categorized into younger (grades 7th and 8th) and …

Identification Of Hypoxia-Inducible Factor Hif1a As A Therapeutic Target During Sars-Cov-2-Associated Lung Injury, Bentley Bobrow, Samuel D Luber, Paul Potnuru, Katherine Figarella, Jieun Kim, Yanyu Wang, In Hyuk Bang, David Robinson, Paulina B Sergot, Steven K Burke, Tingting Mills, Constanza De Dios, Robert Suchting, George W Williams, Adit A Ginde, Yafen Liang, Hongfang Liu, Charles Green, Marie-Francoise Doursout, Alparslan Turan, Daniel I Sessler, Xiaoyi Yuan, Holger K Eltzschig

Faculty, Staff and Student Publications

Hypoxia-inducible factors (HIFs) promote lung protection and pathogen eradication during acute lung injury. We therefore tested the theory that pharmacologic stabilization of HIFs dampens lung injury during SARS-CoV-2 pneumonia. Initial studies in murine SARS-CoV-2 models showed improved outcomes after treatment with the FDA-approved HIF-stabilizer vadadustat. Subsequent studies in genetic models implicated alveolar-expressed Hif1a in mediating lung protection. Therefore, we performed a randomized, double-blinded, multicenter phase 2 trial in patients admitted for SARS-CoV-2 infection and concomitant hypoxia (SpO2 ≤ 94%). Patients (n=448) were randomized to oral vadadustat (900 mg/day) or placebo for up to 14 days. Safety events were similar between …

Rapid Beamformer Weight Calibration Update Method For The Advanced L-Band Phased Array Camera For Astronomy (Alpaca), Kayla Lyman Ward

Theses and Dissertations

The Advanced L-Band Phased Array Camera for Astronomy (ALPACA) is a phased array feed instrument designed for the Green Bank Telescope. It is capable of producing 40 real-time beams on the sky, widening the telescope's field of view and significantly increasing survey speed. ALPACA employs an RF-over-fiber (RFoF) signal transport system from the phased array feed front end to the digital backend. This RFoF link is expected to introduce phase delays and changes in gain through out the course of an observation, invalidating the beamformer weights previously calculated. This work presents rapid beamformer weight calibration updates for ALPACA, a method …

Filtration Challenges In Non-Alcoholic And Low-Alcohol Beer Production With A Focus On Different Yeast Strains, Christian Schubert, Joerg Maxminer, Matthew Aitkens, Andrew Maust, Bernardo Pontes Guimaraes, Rahul Sen, Scott Lafontaine

Food Science Faculty Publications and Presentations

This study examines the impact of yeast selection on fermentation performance, filtration efficiency, and the stability of low-alcohol and non-alcoholic beer (NAB). Three yeast strains (LA-01, LoNa, and W-34/70) were evaluated for their effects on key NAB parameters like ABV, bitterness, color, haze readings, and filtration-linked performance. Filtration trials revealed that highly flocculating W-34/70 resulted in lower post-filtration turbidity, whereas LA-01 and LoNa (which flocculated less) required more effective filtration techniques to achieve clarity. Among the tested filter sheets, AF 31, AF 71, and AF 101 successfully reduced turbidity below 2 EBC. However, all NABs exhibited haze formation during storage, …

Supporting Achievement Motivation In Black And Latine Middle School Students: Development And Evaluation Of The Feasibility And Acceptability Of A Motivational Interviewing Intervention, Austin Roy Cole

USF Tampa Graduate Theses and Dissertations

Participation in accelerated high school curricula can provide substantive post-secondary benefits for students. However, participation continues to reflect disparate enrollment for Black and Latine students. Though organizations and legislatures have sought to improve Black and Latine student enrollment, the enrollment gap has not closed and there is little evidence of improving academic achievement for Black and Latine students beyond increased enrollment. Research shows that when students have their psychological needs of autonomy, competence, and relatedness met, as described by Self-Determination Theory, they demonstrate better academic outcomes and social-emotional development. Barriers reported by students of color reflect these psychological needs. Thus, …

Beyond Diversity Initiatives: Building A Community Of Care In Scientific Societies, Richelle L. Tanner, Kathryn Wilsterman

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

"In this Professional Biologist article, we present one such reframing that centers individualized care through structural changes. We argue that psychological and sociological motivations of belonging and social capital in the academy are funda- mental challenges contributing to the cultural problems within STEM fields and are particularly present within professional scientific societies. In support of this argument, we present survey- based data alongside significant literature from the humanities. In this reframing supported by existing organizational culture literature and our survey results, we suggest that scientific societies are uniquely positioned to promote significant cultural change within STEM by focusing on building …

Effectiveness Of Digital Behavioral Activation Interventions For Depression And Anxiety: Systematic Review And Meta-Analysis, Eric Jia, Jushawn Macon, Michelle Doering, Joanna Abraham

2020-Current year OA Pubs

BACKGROUND: As digital interventions gain prominence in mental health care, they present opportunities to improve access and scalability. Despite their potential, the overall impact of digital behavioral activation (BA) interventions across different formats and populations is not yet fully understood.

OBJECTIVE: This systematic review examines the characteristics and functions of digital BA interventions and evaluates their effectiveness for mental health and other patient-related outcomes.

METHODS: A comprehensive search of databases (PubMed, Embase, Web of Science, APA PsycInfo, and ClinicalTrials.gov) was performed in November 2023 to identify randomized controlled trials (RCTs) assessing the effectiveness of digital BA interventions for depression and …

Btp2 Restricts Tulane Virus And Human Norovirus Replication Independent Of Store-Operated Calcium Entry, Francesca J Scribano, J Thomas Gebert, Kristen A Engevik, Nicole M Hayes, Jorge Villanueva, Son Pham, Soni Kaundal, Janam J Dave, B V Venkataram Prasad, Mary K Estes, Sasirekha Ramani, Joseph M Hyser

Faculty, Staff and Students Publications

Human norovirus is the leading cause of viral gastroenteritis across all age groups. While there is a need for human norovirus antivirals, therapeutic development has been hindered by a lack of cell culture systems and animal models of infection. Surrogate viruses, such as Tulane virus (TV), have provided tractable systems to screen potential antiviral compounds. Our previous work demonstrated that TV encodes a viral ion channel, which dysregulates cytosolic calcium signaling. We set out to investigate whether host pathways triggered by viral ion channel activity, including store-operated calcium entry (SOCE), play a role in virus replication. Using pharmacologic inhibitors and …

Clinical And Radiological Features Of Atypical Adrenal Masses-A Multicenter Retrospective Study, Vania Balderrama-Brondani, Ruaa Al-Ward, Katja Kiseljak-Vassiliades, Lauren Fishbein, Danielle Dawes, Oksana Hamidi, Reza Pishdad, Juan Pablo Perdomo Rodriguez, Mohamad Anas Sukkari, Joseph R Grajo, Hans Kumar Ghayee, Sara Bedrose, Roland L Bassett, Amir H Hamrahian, Mouhammed Amir Habra

Faculty, Staff and Students Publications

Context: The natural history and malignant potential of cases classified as atypical adrenal masses (AAMs) are unknown.

Objective: To describe the radiological characteristics and clinical outcomes of AAMs.

Design and participants: A multicenter retrospective study. Patients ≥18 years old with AAMs [diameter of 10-39 mm on first imaging study and pre-contrast attenuation of >10 Hounsfield units (HU) on computed tomography] were studied. We excluded adrenal metastasis, pheochromocytoma, sarcoma, lymphoma, infiltrative lesions, and adrenal hemorrhage, as well as patients with genetic predisposition to adrenal neoplasms. Data are presented as percentages and median values with interquartile ranges (IQRs).

Results: We included 217 …

Proteogenomic Analysis Of The Calgb 40601 (Alliance) Her2+ Breast Cancer Neoadjuvant Trial Reveals Resistance Biomarkers, Eric J Jaehnig, Aranzazu Fernandez-Martinez, Tanmayi D Vashist, Matthew V Holt, Laterrica Williams, Jonathan T Lei, Chang In Moon, Beom-Jun Kim, Yongchao Dou, Haoquan Zhao, Viktoriya Korchina, Richard A Gibbs, Donna Marie Muzny, Harshavardhan Doddapaneni, Charles M Perou, Lisa A Carey, Ana I Robles, Terry Hyslop, Yujia Wen, Linda Mccart, Azra Krek, Francesca Petralia, George Miles, Shyam M Kavuri, Michael A Gillette, D R Mani, Steven A Carr, Bing Zhang, Matthew J Ellis, Shankha Satpathy, Meenakshi Anurag

Faculty, Staff and Students Publications

Proteogenomic analysis is applied to samples from the CALGB 40601 (Alliance) randomized neoadjuvant trial of trastuzumab, lapatinib, or the combination to identify biomarkers associated with pathological response status. Absence of ERBB2 gene amplification and human epidermal growth factor receptor 2 (HER2) protein overexpression by proteogenomics is associated with non-pathological compete response (pCR) (p < 0.05), highlighting potential false positives from standard diagnostics. Pathway analysis in proteogenomics-confirmed HER2+ samples identifies elevated epithelial-mesenchymal transition (EMT) and WNT-β-catenin signaling in non-pCR cases before treatment. Twenty-four pCR-associated proteins reproduce in a second proteomic dataset, and four (GPRC5A, TPBG, SP140L, and NEU1) are significant in a third. A meta-analysis of ten diverse neoadjuvant anti-HER2 treatment regimens from four independent studies confirms that non-pCR cases express higher levels of mRNA for G protein-coupled receptor class C group 5 member A (GPRC5A, p = 0.0002) and trophoblast glycoprotein (TPBG, p = 0.00008). Thus, proteogenomic analysis identifies negative biomarkers for pCR and alternative plasma membrane targets for treatment-resistant HER2+ breast cancer.