Resilience In Crisis: How Bipoc Educators Navigated The Challenges Associated With Covid-19, Racial Awakening, And The Move To Online Learning, Jannet Galicia Castrejon

Dissertations

An unprecedented number of BIPOC teachers exited the profession since June 2020 largely due to the challenges posted by the COVID-19 pandemic (Doan et al., 2024). This study aimed to investigate ways these educators coped with the heavy toll of the converging pandemic(s) by asking what, if anything, sustained them? Participants provided individual and group testimonios and shared snapshots of what it was like to teach and exist during this time via the photovoice methodology and reflected on the challenges and sources of support. BIPOC teachers described the following challenges: difficulty connecting with kids, first-hand and vicarious trauma, increased workload, …

Imaging Efficacy And Safety Of Low Dose Intraventricular Tissue Plasminogen Activator In Aneurysmal Subarachnoid Hemorrhage: Case Series, Collin Liu, William W Wroe, Hussein A Zeineddine, Bryden Dawes, Michael Giordano, Aaron Mccabe, Ching-Jen Chen, Devin W Mcbride, Aaron M Gusdon, Huimahn A Choi, Spiros L Blackburn

Faculty, Staff and Student Publications

Introduction: Free hemoglobin's release into CSF from blood breakdown is a primary instigator of delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (aSAH). Early clearance of subarachnoid blood with intrathecal (IT) fibrinolytics has shown potential to decrease incidence of DCI. However, the dosage of fibrinolytic needed is not known. We investigated the ability of low dose tissue plasminogen activator (tPA) to rapidly remove subarachnoid clot.

Material and methods: We performed a single center retrospective review of aSAH patients who received IT tPA. Dosing consistent with the CLEAR III trial for IVH was utilized-tPA (1 mg) administered every 8 h via …

Cancer Screening Uptake And Usual Source Of Care Among Hispanic Survivors Of Adolescent And Young Adult Cancer, Eunju Choi, Amy M Berkman, Clark R Andersen, John M Salsman, Andrea C Betts, Joel Milam, Kimberly A Miller, Susan K Peterson, Qian Lu, Christabel K Cheung, Lauren V Ghazal, J A Livingston, Michelle A T Hildebrandt, Susan K Parsons, David R Freyer, Michael E Roth

Faculty, Staff and Student Publications

Purpose: This study examines cancer screening rates and the usual source of care among Hispanic survivors of adolescent and young adult (AYA, aged 15-39) cancer, a group at increased risk for poor health outcomes, including secondary cancers.

Methods: National Health Interview Survey data were analyzed to identify Hispanic survivors of AYA cancer and Hispanic age- and sex-matched non-cancer controls. Breast, cervical, and colorectal screening (ever screened and up-to-date according to the U.S. Preventive Services Task Force recommendations) as well as reporting a usual source of care were compared among survivors and controls eligible for screening using multivariable logistic regressions.

Results: …

2024-04-02 Leadership Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2023-09-19 Executive Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2023-10-03 Executive Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

Conjugative Delivery Of Toxin Genes, Yang Grace Li, Daniel Haeusser, William Margolin, Peter J Christie

Faculty, Staff and Student Publications

The bacterial type IV secretion systems (T4SS) are medically problematic for their roles in the dissemination of mobile genetic elements or effector proteins, but they also have great potential for new antimicrobial therapies. Recent studies have deployed the T4SS subfamily of conjugation systems to deliver gene editing CRISPR/Cas systems to disrupt drug resistance genes or kill targeted bacterial recipients. However, the therapeutic potential of conjugative CRISPR/Cas delivery is compromised by mutations or host repair systems that diminish the efficiency with which CRISPR/Cas induces double-strand breaks in new transconjugants. Here, we compared the efficiencies of conjugation-based killing systems based on the …

2024-04-16 Executive Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2023-12-12 Executive Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2023-08-22 Executive Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

Deformation And Earthquake Potential On The North America - Caribbean - Cocos Triple Junction In Guatemala, Jeremy Maurer, Andreas Eckert, Qiaoqi Sun, Jonathan Obrist-Farner

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

The triple junction between the Cocos (CO), North American (NA), and Caribbean (CA) tectonic plates in Guatemala is a region of high seismic risk and includes many large faults and historic earthquakes. Previous analyses of the tectonic system have been overly simplified, resulting in discrepancies between geologically derived and geodetic models of fault slip rate. This study leverages available geodetic, seismic, and geologic data to develop new strain rate maps and faulting models for the region. We find that locking on the regional faults matches historic reports of large earthquakes and that multiple minor fault segments are active and accommodate …

Graduate Student Paper: Aging In A Changing Japan: Gendered Adaptation To Changing Family Structure, Miki Izu, Clayton Chalmers

Asia Pacific Perspectives

Although Japanese seniors are very healthy, research shows that they are not very happy. Compared to seniors in other developed countries, Japanese elders have lower ratings of subjective well-being and are increasingly alone. This paper argues that changes to Japanese family life help explain why Japanese elders are struggling with low subjective well-being. Specifically, declining marriage rates and declining rates of elders living with their children (co-residency) have made it harder for elders to get the support they need. Moreover, the effect and the adaptations to these changes are not equal between men and women. While elderly Japanese men are …

The Sodium-Glutamate Antagonist Riluzole Improves Outcome After Acute Spinal Cord Injury: Results From The Riscis Randomised Controlled Trial Analysed Using A Global Statistical Analytic Technique, Michael G. Fehlings, Karlo M. Pedro, Mohammed Ali Alvi, Ali Moghaddamjou, James S. Harrop, Ralph Stanford, Jonathon Ball, Bizhan Aarabi, Paul M. Arnold, James D. Guest, Shekar N. Kurpad, James M. Schuster, Ahmad N. Nassr, Karl M. Schmitt, Jefferson R. Wilson, Darrel S. Brodke, Faiz U. Ahmad, Albert Yee, Wilson Z. Ray, Nathaniel P. Brooks, Jason Wilson, Diana S-L Chow, Elizabeth G. Toups, Kevin E. Thorpe, Jiaxin Huang, Peng Huang

Department of Neurosurgery Faculty Papers

BACKGROUND: Spinal cord injury (SCI) clinical trials typically rely on a single primary endpoint to assess drug efficacy. This strategy fails to adequately capture the full impact of treatment in heterogenous neurological conditions like SCI. A more patient-centric analysis requires assessment of neurological function, functional capacity, and quality of life, incorporating meaningful patient-reported outcomes. The global statistical test (GST) addresses this challenge using a unified statistical conclusion regarding the superiority of a treatment strategy over another by evaluating multiple trial endpoints simultaneously.

METHODS: The RISCIS trial (Safety and Efficacy of Riluzole in Acute Spinal Cord Injury Study) data was analysed …

The Relationship Between The Dark Triad And Perceived Career Mobility: The Moderating Role Of Perceived Organizational Support, Julia W. R. Leong

Master's Theses

Prior research on career mobility has found that personality is not a strong predictor of career mobility. However, these studies have mainly focused on the Big Five personality traits and have not looked into other personality traits as predictors. The present study has looked into alternate personality traits and their relationship with perceived internal and external career mobility. These traits were the Dark Triad traits, consisting of Machiavellianism, narcissism, and psychopathy. The present study hypothesized that each of the Dark Triad traits would positively predict both perceived internal and external career mobility and that perceived organizational support (POS) would moderate …

Investigating The Complexity Of Language Acquisition For Linguistically Diverse Children, Krittin Srisajjakul

Master's Theses

Understanding the natural productions of children's early expressive language development is important to support their development. These natural productions may also be especially complex in children with diverse linguistic backgrounds. A challenge for clinicians is how to assess these natural productions for children’s early expressive language milestones. For example, what does it mean for children to say the same word in two languages and refer to the same concept (e.g., “water” and “agua”)? Or refer to two different concepts, (e.g., “water” and “leche” (milk))? By understanding how children’s expressive language connects to conceptual understanding, clinicians can better support language learning. …

A Multi-Modal Pelvic Mri Dataset For Deep Learning-Based Pelvic Organ Segmentation In Endometriosis, Xiaomin Liang, Linda A Alpuing Radilla, Kamand Khalaj, Haaniya Dawoodally, Chinmay Mokashi, Xiaoming Guan, Kirk E Roberts, Sunil A Sheth, Varaha S Tammisetti, Luca Giancardo

Faculty, Staff and Students Publications

Endometriosis affects approximately 190 million females of reproductive age worldwide. Magnetic Resonance Imaging (MRI) has been recommended as the primary non-invasive diagnostic method for endometriosis. This study presents new female pelvic MRI multicenter datasets for endometriosis and shows the baseline segmentation performance of two auto-segmentation pipelines: the self-configuring nnU-Net and RAovSeg, a custom network. The multi-sequence endometriosis MRI scans from two clinical institutions were collected. A multicenter dataset of 51 subjects with manual labels for multiple pelvic structures from three raters was used to assess interrater agreement. A second single-center dataset of 81 subjects with labels for multiple pelvic structures …

Project Evolve: An International Analysis Of Postimmunotherapy Lineage Switch, An Emergent Form Of Relapse In Leukemia, Sara K Silbert, Alexander W Rankin, Chloe N Hoang, Alexandra Semchenkova, Regina M Myers, Elena Zerkalenkova, Hao-Wei Wang, Alexandra E Kovach, Constance M Yuan, Dana Delgado Colon, Loïc Vasseur, Alex Bataller, Samuel John, Kaylyn Utley Lyons, Barbara Friedes, Anna Alonso-Saladrigues, Hisham Abdel-Azim, Estelle Balducci, Ahmed Assim Aljudi, Marie Balsat, D Nathan Biery, Aghiad Chamdin, Bill H Chang, Raymund S Cuevo, Barbara De Moerloose, David S Dickens, Ulrich Duffner, Nicolas Duployez, Firas El Chaer, Michelle Ann Elliott, Gabriele Escherich, Sneha Fernandes, Mandi R Fitzjohn, Zhubin Gahvari, Stephan A Grupp, Rui Rochelle He, Cynthia Harrison, Christopher B Hergott, Emily M Hsieh, Annette S Kim, Dennis J Kuo, Daniel P Larson, Benjamin J Lee, Thibaut Leguay, R Coleman Lindsley, Abhishek A Mangaonkar, Kerstin Mezger, Holly L Pacenta, Jing Pan, Marlie Provost, Latika Puri, Sunil S Raikar, Armando Martinez, Isabella Bristol, Kyle Murphy, Lauren Reiman, Michele Redell, Kelly Reed, Gabrielle Roth-Guepin, Jeremy Rubinstein, Süreyya Savaşan, Kristian Schafernak, Alexandra Stevens, Aimee Talleur, Naomi Torres Carapia, Jacques Vargaftig, Anant Vatsayan, Matthias Wölfl, Liping Zhao, Susana Rives, Vanessa A Fabrizio, Koji Sasaki, Ibrahim Aldoss, Nicolas Boissel, Susan R Rheingold, Kara L Davis, Sara Ghorashian, Elad Jacoby, Alexander Popov, Adam J Lamble, Nirali N Shah

Faculty, Staff and Students Publications

Lineage switch (LS), defined as the immunophenotypic transformation of acute leukemia, has emerged as a mechanism of relapse after antigen-targeted immunotherapy, which is associated with dismal outcomes. Through an international collaborative effort, we identified cases of LS after a host of antigen-targeted therapies (eg, CD19, CD22, CD38, and CD7), described how LS was diagnosed, reviewed treatment approaches, and analyzed overall outcomes for this form of postimmunotherapy relapse. Collectively, 75 cases of LS were evaluated, including 53 (70.7%) cases of B-cell acute lymphoblastic leukemia (B-ALL) transforming to acute myeloid leukemia (AML), 17 (22.7%) cases of B-ALL transforming to mixed phenotypic acute …

Anxious Traits Intensify The Impact Of Depressive Symptoms On Stigma In People Living With Hiv, Alexia Koukopoulos, Antonio Maria D'Onofrio, Alessio Simonetti, Delfina Janiri, Flavio Cherubini, Paolo Vassalini, Letizia Santinelli, Gabriella D'Ettorre, Gabriele Sani, Giovanni Camardese

Faculty, Staff and Students Publications

Background/Objectives: Despite medical advances, stigma remains a major challenge for people living with HIV (PLWH). This study examined clinical, sociodemographic, and psychological predictors of HIV-related stigma, and explored whether affective temperament moderates the impact of depression on stigma.

Methods: This cross-sectional observational study included 97 PLWH attending a tertiary infectious disease unit in Rome, Italy. Participants completed a battery of validated psychometric instruments assessing depressive symptoms, anxiety, manic symptoms, mixed affective states, general psychopathology, impulsivity, and affective temperament. HIV-related stigma was evaluated using the Berger HIV Stigma Scale, which measures personalized stigma, disclosure concerns, negative self-image, and concerns …

Achieving Equity For International Medical Graduates: A Systematic Review, Sangeeta G. Saxena, Elizabeth Tisdell, Elana Farace, Thomas Godfrey, Betsy Aumiller, Esther Dell, Omrana P. Razzak, Bernadette N. Kumar, Kristin K. Sznajder

Public Health

Introduction: Foreign-born and foreign trained International Medical Graduates (FIMGs) face greater challenges in acculturation to their host countries than IMGs who train abroad and return to practice in their home country. As FIMGs are likely to fulfill a shortage of physicians in High Income Countries in the foreseeable future, we conducted a systematic review of literature to identify acculturation interventions that help FIMGs assimilate better in their host country health systems. This improves their productivity and satisfaction, allows health systems to be more accepting of FIMGs, and most importantly, enhances patient outcomes.

Methods: Following the PRISMA statement, we searched PubMed, …

Mapping The Literature On Short-Selling In Financial Markets: A Lexicometric Analysis, Nitika Sharma, Sridhar Manohar, Bruce A. Huhmann, Yam B. Limbu

Department of Marketing Faculty Scholarship and Creative Works

This study provides a comprehensive assessment and synthesis of the literature on short-selling. It performs a lexicometric analysis, providing a quantitative review of 1093 peer-reviewed journal articles to identify and illustrate the main themes in short-selling research. Almost half the published literature on short-selling is thematically clustered around portfolio management techniques. Other key themes involve short-selling as it relates to risk management, strategic management, and market irregularities. Descending hierarchical classification examines the overall structure of the textual corpus of the short-selling literature and the relationships between its key terms. Similarity analysis reveals that the short-selling literature is highly concentrated, with …

Effects Of Intermittent Fasting On Glycemic Markers In Patients With Insulin Resistance, Caitlin Malon

Summer Interdisciplinary Research Symposium

Objective: The purpose of this research investigation is to evaluate the impact of intermittent fasting on glycemic control in patients with prediabetes or metabolic syndrome.

Methods: A structured literature review was conducted using Google Scholar to identify relevant studies published within the last five years. Search terms included "Insulin Resistance, Intermittent Fasting," "Prediabetes, Intermittent Fasting," and "Intermittent Fasting, Metabolic Syndrome." Inclusion criteria were English-language, full-text articles focusing on intermittent fasting interventions in populations with prediabetes or metabolic syndrome. Studies were excluded if they were published more than five years ago, focused solely on weight loss, or included participants …

Adjunctive Radiotherapy In The Management Of Atypical Meningiomas, Madison Janickovic

Summer Interdisciplinary Research Symposium

Objective: This study aims to evaluate whether post-operative adjunctive radiotherapy (PORT) reduces recurrence rates and improves overall survival (OS) in patients diagnosed with grade II/atypical meningiomas (AMs).

Methods: A systematic search was conducted using Google Scholar with primary search terms including “meningiomas,” “surgical resection,” and “radiotherapy,” yielding 4,830 results. Inclusion criteria were limited to peer-reviewed articles published in English from 2019 or later. Studies published before 2019 or in non-English languages were excluded. Key outcomes analyzed included recurrence rates, progression-free survival (PFS), and overall survival.

Results: Evidence suggests that PORT following gross total resection (GTR) of AMs does not significantly …

Comparing Monophasic Vs. Biphasic Hyaluronic Acid Filler For Facial Enhancement, Kaitlyn M. Carr

Summer Interdisciplinary Research Symposium

This capstone project aims to compare the efficacy, patient satisfaction, side effects, and longevity of results between monophasic and biphasic hyaluronic acid fillers over a 12-month period. A systematic literature review was conducted using three databases: Google Scholar, PubMed, and the library of Valparaiso University. Keywords included “comparison between hyaluronic acid fillers” and “monophasic and biphasic hyaluronic acid filler.” The search returned approximately 30,300 results on Google Scholar, 2 results on PubMed, and 365 results from Valpo’s database, with results filtered to include studies published in English since 2019 and with full-text availability. Exclusion criteria included studies involving participants under …

Fresh Frozen Plasma Ratio And Its Effect On Trauma Patient Survival, Morgan R. Lareau

Summer Interdisciplinary Research Symposium

Objective: This study aimed to evaluate whether a high fresh frozen plasma (FFP) to red blood cell (RBC) ratio transfusion reduces mortality rates compared to a lower ratio in trauma patients, focusing on 24-hour, in-hospital, and 30-day mortality outcomes.

Methods: A systematic literature review was performed using Google Scholar, PubMed, and the Valparaiso University catalog. Keywords included “FFP/RBC ratio,” “trauma patients,” and “mortality rate,” resulting in 5,140, 39, and 1,660 articles respectively. Inclusion criteria limited studies to those published from 2019 onward, in English, peer-reviewed, with full-text availability, and focused on trauma patients receiving FFP to RBC ratio. Excluded studies …

Efficacy Of Berberine In Glucose And Metabolic Control, Grace Poduch

Summer Interdisciplinary Research Symposium

Objective: Type 2 diabetes mellitus (T2DM) is a common chronic disease with significant complications if poorly managed. This study evaluated the effectiveness of berberine--the primary active compound in Rhizoma Coptidis-- compared to metformin, a widely used oral hypoglycemic agent, in managing blood glucose in adults with T2DM. It also examined berberine's impact on metabolic syndrome components, including prediabetes, hyperlipidemia, obesity, and chronic inflammation.

Methods: A literature review was conducted using Google Scholar and PubMed with keywords including "berberine", "Rhizoma Coptidis", "metformin", and "type 2 diabetes". Included studies were full-text, published in English since 2019, and involved adult humans with …

Platelet-Rich Plasma Vs. Corticosteroid Injections For Rotator Cuff Tendinopathy: A Literature Review, Adam J. Nieman

Summer Interdisciplinary Research Symposium

Objective: This literature review aims to compare the efficacy of platelet-rich plasma (PRP) and corticosteroid (CS) injections for treatment of rotator cuff tendinopathy (RCT). The primary outcomes of interest include changes in pain and shoulder function following injection therapy.

Methods: A systematic literature search was conducted using Google Scholar, PubMed, and EBSCOhost via Valparaiso University’s library system. Keywords included: plasma, PRP, platelet-rich plasma, platelets, steroids, corticosteroids, injection, therapy, intervention, treatment, rotator cuff, rotator cuff tendinopathy, rotator cuff disease, rotator cuff injury, rotator cuff tendinitis, and impingement syndrome. The search yielded 5,300 results on Google Scholar, 27 on PubMed, …

Effective Pain Control Strategies For Outpatient Gynecologic Procedures, Andrea Luekens

Summer Interdisciplinary Research Symposium

Objective: To evaluate whether the benefits of prescription pain medications outweigh their risks in managing pain during standard outpatient gynecologic procedures.

Methods: A structured literature review was conducted using Medline via EBSCO, covering studies from January 2019 to December 2024. Search terms included variations of "pain management" combined with "gynecology" and "procedure." Of 507 identified articles, studies were included if they were in English, full-text, and involved adult patients with female reproductive anatomy undergoing outpatient gynecologic procedures. Exclusion criteria included participants under 18, studies older than five years, and those involving surgery, maternal-fetal procedures, or childbirth. Primary outcome: patient-reported pain; …

Monoclonal Antibodies Or Cholinesterase Inhibitors? Cognitive Impact On Alzheimer’S Disease, Alexandra M. Herbert

Summer Interdisciplinary Research Symposium

This research evaluates and compares the effectiveness of monoclonal antibodies (mAbs) and cholinesterase inhibitors (ChEIs) in reducing cognitive decline in Alzheimer’s disease. A structured literature review was conducted using Google Scholar and Medline, yielding over 6,000 articles. Studies were included if they involved Alzheimer’s patients, evaluated either mAbs or ChEIs, measured cognitive outcomes, were published since 2019, and were available in English with full-text access. Studies were excluded if they focused on non-Alzheimer’s populations, alternative therapies, or were published before 2019. Monoclonal antibodies such as aducanumab, lecanemab, and donanemab showed statistically significant improvements in cognitive scores; however, these changes were …

Disease Modifying Drugs In Osteoarthritis: Structural & Symptomatic Outcomes, Peyton F. Weber

Summer Interdisciplinary Research Symposium

Objective: This capstone project aimed to evaluate whether proposed disease-modifying osteoarthritis drugs (DMOADs), compared to placebo, can slow or halt structural joint changes and subsequently improve pain and function in adults with osteoarthritis (OA).

Methods: A systematic review was conducted using PubMed, Google Scholar, and EBSCO, focusing on studies published since 2019 that evaluated proposed DMOADs (lorecivivint, sprifermin, chondroitin, and glucosamine) versus placebo in adults with clinical or radiographic knee OA. Inclusion required reporting on joint space width (JSW), pain, and/or function. Studies involving pediatric or animal subjects, prior joint surgery, malignancy, and non-placebo comparators, or lacking structural or symptomatic …

The Efficacy Of Continuous Versus Luteal Ssri Dosing In Pmdd, Natalie Swierczynski

Summer Interdisciplinary Research Symposium

This research aims to determine whether intermittent (luteal phase) or continuous selective serotonin reuptake inhibitor (SSRI) dosing is more effective in reducing symptoms of premenstrual dysphoric disorder (PMDD). A structured literature review was conducted using Google Scholar, PubMed, and the Christopher Center Library database. Search terms included “PMDD,” “premenstrual dysphoric disorder,” “SSRIs,” “continuous dosing,” “intermittent dosing,” and “luteal phase.” Inclusion criteria were English-language studies involving adult women with full-text availability and examining continuous and/or intermittent SSRI use. Exclusion criteria included non-English publications, unavailable full texts, and pediatric populations.

Sixteen sources were selected: five empirical studies (randomized controlled trials and observational …