Development Of Computational Imaging Pipelines To Advance Virtual Pet Imaging Trials, Suya Li

McKelvey School of Engineering Graduate Student Theses & Dissertations

Positron emission tomography (PET) provides functional information that is essential for disease diagnosis, treatment assessment, and biomedical research. However, the development and validation of PET imaging methods often require simulated imaging data with known ground truth, as well as large clinical datasets that are realistic and scalable. These requirements are difficult to satisfy using clinical studies alone, motivating the development of virtual PET imaging techniques. Physics-based simulation can model PET acquisition with high accuracy, but its computational cost limits its large-scale usage. Meanwhile, conventional digital phantom-based image generation approaches often lack the anatomical diversity and heterogeneous tracer uptake patterns observed …

Talking Teaching For Change: How Productive Teacher Collaborations Contribute To Teacher Efficacy Beliefs And Student Achievement Gains, Xiaohang Zhang

Theses and Dissertations

Teacher collaboration and teacher efficacy beliefs are complex, multifaceted constructs that play critical roles in student learning and influence one another in multiple ways. School collaborative culture, including collegial trust, collective learning, and shared responsibility, has also been identified as an important factor shaping both effective teacher collaboration and teacher efficacy beliefs. This study employed a sequential explanatory mixed-methods design to (a) examine the relationships between features of collaborative discourse and teachers' instructional efficacy beliefs, as well as the extent to which school type and school collaborative culture influence these relationships, and (b) explore how these collaborative discourse features are …

From The Forests With Hopes Of Paradise: Malay Muslims In The Victorian Imagination In Joseph Conrad's Lord Jim, M Irfan Zamzami, Rifka Pratama

Journal of Language, Literature, and Arts

This article examines how Lord Jim constructs and reconfigures Muslim identities within the discourse of British imperialism. While previous scholarship has explored the novel’s colonial politics, less attention has been paid to how its representations of Malay Muslims reveal the instability of Orientalist categories. Using Edward Said’s concept of Orientalism and Homi Bhabha’s theory of colonial ambivalence, the study applies close textual analysis of two key narrative moments: the omniscient narrator’s description of the Muslim pilgrims aboard the Patna and the depiction of Malay Muslims in Patusan. The analysis demonstrates that the Patna pilgrims are initially represented through familiar Orientalist …

Safety Of Early Discharge And Abbreviated Nimodipine Course In Patients With Good-Grade Aneurysmal Subarachnoid Hemorrhage, Patrick R. Toyota, Alexander D. Rebchuk, Michael A. Rizzuto, Hugh Mchugh, Kelsey Cruz, Charles S. Haw, Gary J. Redekop, Peter Gooderham

Department of Neurosurgery Faculty Papers

Aneurysmal subarachnoid hemorrhage (aSAH) remains a devastating cerebrovascular emergency associated with substantial morbidity and mortality. Current guidelines recommend 14-21 days of inpatient monitoring and a 21-day course of nimodipine following aSAH. This retrospective study evaluates early outcomes early discharge (≤14 days post-ictus) and an abbreviated nimodipine course in highly selected patients with good-grade aSAH managed under a standardized institutional protocol. Consecutive patients enrolled in the Vancouver Ruptured Aneurysm Database (VRAD) at Vancouver General Hospital between 2022 and 2025 were included. Inclusion criteria were good-grade aSAH (WFNS Grade I-III) and discharge home within 14 days of ictus. The primary outcome was …

Ƒ(Enlightenment): A Complex Adaptive Systems Model Of Recursive Causality And Human Meaning-Making, Daniel Lambert

Dissertations and Theses

Conflict Resolution has developed as a richly interdisciplinary field; however, its theoretical architecture remains fragmented across distinct bodies of scholarship. Existing approaches offer valuable but often isolated explanations of conflict behavior, limiting their ability to account for its complexity. This thesis addresses this limitation by advancing systems science as an organizing framework for integrating these perspectives. It introduces the Human-Complex Adaptive Systems (H-CAS) framework, which conceptualizes human behavior as a recursive adaptive process operating across interconnected regulatory domains. Within this model, conflict is not treated as a discrete event or purely deliberative process, but as an emergent property arising from …

Pathogenic Myeloid Phenotypes Drive Disease Pathology In A Novel Human Neurohistiocytosis Model, Shivakumar Rajamanickam, Samantha Trescott, Samantha Mak, Anna S Warden, Amanda M Wilpitz, Bing Xia, Celina Nguyen, Hilda Ding, Jennifer Picarsic, Christopher K Glass, Carl E Allen, Nicole G Coufal

Faculty, Staff and Students Publications

Innate immunity is increasingly recognized as a driver of neurodegeneration, although pathogenic mechanisms are incompletely understood. Langerhans cell histiocytosis (LCH) is an inflammatory myeloid neoplastic disorder caused by activating somatic mutations in MAPK pathway genes, most commonly BRAFV600E, in myeloid precursors. A subset of patients with LCH develop progressive neurodegeneration (LCH-ND). We generated a human induced pluripotent stem cell (iPSC) model from patients with somatic hematologic mosaicism for BRAFV600E. Brain macrophages/microglia from LCH iPSCs exhibit unique disease-specific pathogenic features. Stepwise differentiation identified hematopoietic progenitors as hyperproliferative, whereas brain macrophages were apoptosis resistant. Through application of cerebral organoids and a humanized …

Parental Enculturation And Child Well-Being In Immigrant Families: Examining Peer Relationship Difficulties And Emotional Symptoms In Asian American Youth, Yuxin Yu

LSU Master's Theses

Parents with immigration backgrounds face the dual challenges of maintaining their heritage culture while supporting their children’s adaptation to the mainstream culture. Although previous studies stressed both acculturation and enculturation, these two processes can compete and even conflict, leading to the important question for parents: Does parental enculturation influence children’s peer relationships and emotional functioning? This study examines the associations between parental enculturation and the social and emotional adaptation of Asian American youth by focusing on peer relationship difficulties and emotional symptoms. Participants included 75 Asian American parents of children aged 4 to 17, who completed measures of parental enculturation …

Where Art Thou Resident? Past, Present And Future Of Tax Residency Certificates, Bijal Ajinkya, Anuraag Bukkapatnam

National Law School Business Law Review

A Tax Residency Certificate (‘TRC’) is an essential document enabling non-residents to claim tax treaty benefits in India. However, whether a TRC is sufficient in order to claim such benefits has been the subject matter of litigation, particularly in cases involving treaty shopping/tax fraud allegations. The Supreme Court in the case of Azadi Bachao Andolan endorsed the Government’s circulars, which gave primacy to TRCs while evaluating the tax residency of non-residents. However, a recent decision of the Supreme Court in the case of Tiger Global Investment Holdings has seemingly departed from this principle, citing a change in the underlying law …

Developing A Natural Language Interface For Knowledge Graphs, Ruth Assefa, Sarah Mendoza, Luke Voinov, Oyku Serap Ogut, Nurcan Yuruk

SMU Journal of Undergraduate Research

This paper proposes to solve the challenge of making databases more user-friendly by interfacing them with OpenAI's ChatGPT-3.5 model. We implemented this solution to assist researchers in easily finding others with similar research interests. Our study involves 184 researchers from 14 departments at Southern Methodist University (SMU). We collected researchers' areas of expertise and biographies and stored them in a Neo4j graph database. We used OpenAI's embedding models to create vector representations of the collected data, allowing for accurate similarity assessments via Neo4j's built-in algorithms. By integrating this system with LangChain, we enabled natural language queries. The results demonstrated high …

Stylometric And Formal Patterns In The Scholarly Impact Of Scientific Literature, Joshua Ange, Eric Godat, Rajani Sudan

SMU Journal of Undergraduate Research

Scientific communication is typically tied to promoting public engagement and interest in science, increasing scientific literacy, and playing an essential role in policymaking. The success of public communication of scientific findings is largely associated with secondary characteristics of research (e.g. the style of writing and presentation), rather than the primary content or research quality. But it is unclear to what extent the success of scientific literature intended for working scientists is influenced by those same secondary characteristics. Does the writing style of scientific articles impact their success in academic spheres? In this study, we explore the stylometric and formal characteristics …

Framing Ecclesiastical Issues As Identity Questions: A Comparative Analysis Of Digital Media In North Macedonia And Montenegro, Martin Protogjer

Occasional Papers on Religion in Eastern Europe

This article examines how digital media frame ecclesiastical issues as identity questions in North Macedonia and Montenegro. The analysis compares two distinct but structurally related cases: the media reception of the recognition and normalization of the status of the Macedonian Orthodox Church – Ohrid Archbishopric in North Macedonia in 2022, and the media reception of the Law on Freedom of Religion and the church processions associated with the Serbian Orthodox Church in Montenegro in 2020. The study employs qualitative content analysis with a framing approach, based on two purposively selected digital media corpora consisting of 20 media texts from North …

Book Review - Lindsay Pérez Huber And Susana Muñoz, Why They Hate Us: How Racist Rhetoric Impacts Education, (New York, Ny: Teachers College Press, 2021), 240 Pages, Isbn: 0807764981, Olufemi Oyebade

Global Africa: Journal of African and African Diaspora Studies

No abstract provided.

Language And Culture: Exploring The Links Between Africans And African Americans, Joash J. Gambarage

Global Africa: Journal of African and African Diaspora Studies

Due to the generational distance between contemporary African Americans and the earliest generations of enslaved Africans, the deep cultural connection between these two groups has not been sufficiently explored. Moreover, much of the existing literature on African culture in the Americas primarily focuses on retentions related to religion, music, food, and language, often missing other critical aspects of cultural continuity within the African diaspora, such as African American Vernacular English (AAVE) and Niger-Congo linguistic ties, naming practices, and African epistemologies. This exclusion limits our understanding of how the historical movement of Africans and the persistence of African cultural legacies, have …

“It Was The Women Who Kept It On”: The 1984–85 National Union Of Mineworkers Strike In Wales, Brett Bodily

The Thetean: A Student Journal for Scholarly Historical Writing

On March 3rd, 1984, more than 140,000 miners, all members of the National Union of Mineworkers (NUM) walked out on strike in protest of proposed colliery, or “pit” closures. Years of disputes culminated in a major showdown between the largest labor union in the United Kingdom and a resurgent national conservatism led by Margaret Thatcher— leader of the Tory party. The communities built around coal mining recognized the Tory pit closure plan for what it was—an existential threat to their way of life. Women within these communities rose to the occasion and took on leadership and organizational responsibilities, many for …

Pharmacological Potential Of Pomelo (Citrus Maxima) Peel: A Bibliometric Review Of Global Research Trends And Future Directions, Indah Zunita Sari, Alma Nur Azizah, Fitriana Nur Hanifah, David Fernando, Agung Endro Nugroho, Abdul Rohman

Journal of Food and Drug Analysis

Pomelo (Citrus maxima) is a widely cultivated tropical fruit with global production reaching approximately 8.55 million tons in 2023. This large-scale production generates a substantial amount of peel waste despite the fact that pomelo peel contains secondary metabolites with promising pharmacological potential. This study aimed to evaluate global research trends related to the pharmacological potential of pomelo peel using a bibliometric and review-based approach, as well as to identify future research directions. Data were collected from the Scopus database and filtered for English-language scientific articles, reviews, and conference proceedings. The analysis was performed using the Biblioshiny and VOSviewer …

When Auditors Trust Ai: A Qualitative Study Of Professional Judgment, Data Quality, And Adoption Barriers In Lebanon, Joseph Serghani

Arab Economic and Business Journal

This study explores auditors’ trust in AI in a limited-resource and turbulent context, namely Lebanon. Using semi-structured interviews with 14 junior and senior auditors in Lebanon, this study identifies the factors that make auditors either willing or unwilling to trust in AI-powered audit processes. The results indicate that auditors perceive the potential benefits of AI, such as increased speed, capacity, and ability to detect anomalies. Yet, trust in AI is limited by concerns about implementation costs, the erosion of professional judgment, blockchain complexity, data overload, and reliance on high-quality data. Instead of excluding AI from the equation, auditors perceive it …

The Influence Of Prenatal Exercise On Pregnancy Outcomes, Nadhia M. Manthuruthil

Summer Interdisciplinary Research Symposium

Objective: To evaluate the effects of prenatal exercise among pregnant individuals on pregnancy complications and to determine whether exercise modality influences pregnancy outcomes.

Methods: A narrative literature review was conducted using Research Rabbit and PubMed to identify studies examining exercise during pregnancy and associated maternal and fetal outcomes. Eligible studies included English-language, full-text, peer-reviewed articles and systematic reviews published after 2020 involving healthy pregnant patients, with pregnancy outcomes as the primary outcome measure. Studies without measurable outcomes or involving pre-existing comorbidities were excluded.

Results: Prenatal exercise was consistently found to be safe and associated with improved maternal outcomes. Four studies …

The Therapeutic Effects Of Bee Venom And Its Implication For Future Practice, Anna Speckhard

Summer Interdisciplinary Research Symposium

Objective: Bee venom acupuncture (BVA) has been used in Asia for its anti-inflammatory effects for hundreds of years, and recently it has proposed anti-cancer effects. The purpose of this paper is to evaluate the anti-inflammatory and anti-cancer effects of bee venom to determine its use in future medical practice.

Methods: A literature search was conducted using the databases PubMed and Google Scholar with search terms including bee venom therapy, BVA, pain, cancer, and melittin. Inclusion criteria were studies investigating bee venom in the context of pain or cancer. Exclusion criteria were studies with no evaluation of bee venom and endpoints …

“Beyond Weight Loss: Evaluating The Anti-Inflammatory Potential Of Glp-1 Receptor Agonists In Hidradenitis Suppurativa”, Lindsey Roos

Summer Interdisciplinary Research Symposium

Objective: The purpose of this narrative literature review was to evaluate the role of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) as adjunctive therapy in adults with moderate-to-severe Hidradenitis suppurativa (HS). The clinical question explored whether GLP-1 RAs improve disease severity, flare frequency, quality of life, and metabolic outcomes in patients with obesity or metabolic dysfunction.

Methods: A literature review was conducted using Google Scholar, PubMed Central, Christopher Center Library, NIH resources, Research Rabbit, and JAMA Dermatology. Studies published from 2019 to 2025 were reviewed. Inclusion criteria included adults with clinically confirmed moderate-to-severe HS (Hurley stage II–III), measurable baseline disease severity, …

Cognitive Impairment In Heart Failure: Implications For Clinical Practice And Patient Care, Shiya Kamra

Summer Interdisciplinary Research Symposium

Objective: The purpose of this literature review was to evaluate whether adults with heart failure, compared with adults without heart failure, have an increased risk of cognitive impairment and dementia.

Methods: A narrative literature review used Google Scholar to identify studies evaluating cognitive outcomes in adults with congestive heart failure. Inclusion criteria: English-language full-text articles published since 2020, with one 2018 longitudinal study also selected due to its strong methodology. Studies involving pediatric populations or lacking cognitive outcomes were excluded. Five studies met the inclusion criteria.

Results: The review included three systematic reviews/meta-analyses, one cross-sectional study, and one longitudinal cohort …

Evaluating Academic Outcomes In Healthcare Students: Hybrid Learning Compared To Traditional Instruction, Amanda Willy

Summer Interdisciplinary Research Symposium

Objective

The goal of this study was to evaluate academic performance of students in professional healthcare programs utilizing hybrid learning compared to traditional in-person instruction.

Methods

A narrative literature review using Google Scholar was conducted to identify relevant studies. Inclusion criteria consisted of publication since 2019, English full text, and a focus on students in healthcare education programs participating in hybrid or distance learning models. The primary outcomes were measures of academic performance including test scores and board examination pass rates.

Results

Data regarding board pass rates were significantly limited by a lack of statistical analysis. Raw data on hybrid …

Navigating Topical & Biologic Therapies In Pediatric Patients With Lamellar Ichthyosis, Eileen E. Uthuppan

Summer Interdisciplinary Research Symposium

Objective:

The purpose of this literature review was to evaluate the effectiveness and safety of topical retinoid and biological therapies for pediatric patients with Lamellar Ichthyosis. These therapies were compared with standard keratolytic and emollient treatments in improving scaling severity, dryness, pain, pruritus, quality of life, while minimizing infection rates and adverse effects.

Methods:

A narrative literature review was completed using PubMed, EBSCO, Google Scholar, and Research Rabbit Al. Studies in English, within five years, were included if they evaluated pediatric patients with autosomal recessive congenital ichthyosis and had full-text availability. Studies involving adults, non-hereditary ichthyosis, or patients with comorbidities …

Equivocation Analysis Across Continuous And Discrete Memoryless Channels, Md Munibun Billah

Theses and Dissertations

Physical-layer security uses the noise already present in the channel to keep a message secret without making any assumption about the eavesdropper's computing power. In Wyner's wiretap channel model, coset coding uses randomness to map the message to many codewords and protects against information leakage from an active eavesdropper. The secrecy provided by such codes is measured by their equivocation, which is the eavesdropper's remaining uncertainty about the message after she observes her channel. So computing equivocation is an important aspect of analyzing the wiretap channel model. Many channels of practical interest have no closed-form expression for equivocation, and exact …

Upright: Zheng 正 And The Semantics Of Political Legitimacy, Kaz Wegmuller

Open Educational Resources

This article examines the semantic structure of the left-right political binary in contemporary Anglophone discourse. It argues that the fusion of “right” as directional orientation with “right” as moral correctness produces a form of semantic over-determination that complicates the articulation of democratic legitimacy in periods of political crisis. The claim is not that directional metaphors determine political outcomes, but that they furnish a discursive resource that can be mobilized in struggles over authority, order, and rectitude. To illuminate the contingency of this fusion, the article turns to the East Asian concept of zheng 正 (uprightness), whose semantic independence from handedness …

Bridging The Gap: Using A Regional Pediatric Intensive To Improve Rural Nursing Students’ Self-Efficacy, Hannah J. Sasser, Will Brewer

Theses

Abstract

Introduction: Valuable clinical learning opportunities is essential, yet often an unmet goal in nursing education, especially within rural associate degree nursing (ADN) programs, where access to high-acuity and diverse clinical experiences is limited.

Background: Nursing students in geographically isolated areas face limited access to specialty clinicals, including pediatrics, creating inadequacies in clinical learning and preparedness (Institute of Pediatric Nursing, 2021).

Purpose: The purpose of this project was to evaluate the effect of a two-day pediatric intensive, incorporating simulation scenarios and micro-learning activities, on the self-efficacy and satisfaction with learning of students in a rural ADN program. …

Enhancing Resilience For Well-Being To Reduce Health Inequity In Global Nursing Professionals, Fiona Yu, Deborah Raphael, Lisa Mackay, Melody Smith, Ritin Santiago Fernandez

International Nursing Research Congress (INRC)

Nurses, as the largest population in the healthcare service, play a critical role in achieving global health equity to sustain the health of the entire population (1). They are key when providing care in health promotion, disease prevention, treatment, and rehabilitation across diverse populations and clinical settings (2). However, nurses face significant challenges, and the COVID-19 pandemic has exacerbated their situations. Specifically, nursing shortages have a significant impact on frontline nurses, contributing to a heavy workload and unsafe practice, and placing them at a high risk of burnout, stress, fatigue, and ill health, thereby increasing turnover (3, 4).

Research shows …

Ecological Momentary Assessment Of Caregiver Distress In Home Hospice Caregivers: A Study Protocol, Tuzhen Xu, Ya-Ching Huang

International Nursing Research Congress (INRC)

Background: Caregivers of hospice patients, often family or close friends, provide continuous support for individuals with a life expectancy of six months or less. In 2022, 1.72 million Medicare beneficiaries received hospice care, most at home, with an average stay of 98 days. Caregivers manage medications, symptoms, personal care, emotional support, and provider coordination, placing them at high risk for fatigue, anxiety, depression, sleep disturbance, and burnout. Traditional surveys or single-point interviews often fail to capture the dynamic nature of distress, especially during nighttime care or crises.

Purpose: To characterize real-time patterns of physical and psychological distress among home hospice …

Hybrid Podcasts And Shadow Play Model For Teaching Medical Taiwanese: A Mixed-Methods Study, Hsiao-Ying Wu, Yu-Huan Chao

International Nursing Research Congress (INRC)

Background: Effective communication in patients’ native languages is vital for patient-centered care in aging, multilingual societies such as Taiwan. Although Taiwanese (Holo) is widely spoken among older adults, systematic instruction in “Medical Taiwanese”—the clinical application of Holo—remains limited. Most studies emphasize English language learning, leaving a gap in culturally grounded healthcare language education.

Aim: To evaluate the effectiveness of integrating podcast-based scenario dialogues and shadow play role-plays into nursing courses compared with traditional lectures.

Design: Quasi-experimental pre–post control group design with explanatory qualitative inquiry.

Setting and Participants: Conducted at a university of science and technology in northern Taiwan with 122 …

Innovations In Educational Leadership To Improve Nursing Student Attendance And Engagement, Ritin Santiago Fernandez, Eleni Kata

International Nursing Research Congress (INRC)

Background: Nurse education is adapting to an evolving healthcare landscape marked by technological advances, resource constraints, and shifting patient demographics (1) Absenteeism among nursing students in classroom and clinical settings poses significant challenges to academic performance, clinical competency, and program completion (2,3). Effective leadership and advances in education are essential to identify underlying causes and implement strategies that foster students’ engagement to improve their learning outcomes thus preparing a competent healthcare workforce (4).

Aim: This scoping review aimed to map the literature on absenteeism among undergraduate nursing students, highlighting leadership and advances in education. Objectives included: (a) identifying factors contributing …

Exploring Caregiving Choice In The Adult Cancer Population, Jennifer L. Huggins

MUSC Theses and Dissertations

ABSTRACT Purpose Although extensive research examines family caregivers (FCs) across populations, less attention has been paid to how lack of choice in assuming the role affects quality of life (QOL) among FCs of adults with cancer. Understanding choice could guide interventions protecting this invaluable, often invisible workforce. Aims (1) Synthesize what is known about perceived choice among informal caregivers of adults with serious illness; (2) assess relationships between caregiving choice and caregiver QOL, burden, sleep, depression, stress, and social determinants of health; (3) describe experiences of FCs of adults with cancer providing care with no, little, or some choice. Design …