Digital Commons Network^™

Whole-Blood Cellular Responses: A Promising Indicator Of Sars-Cov-2 Immunity Compared To Serology, Lucas M. Zhou, Elizabeth H. Duncan, Rupsa C. Boelig, Margaret Costanzo, Jeffrey R. Currier, Elke S. Bergmann-Leitner

Department of Obstetrics and Gynecology Faculty Papers

Background: Currently available immunological tests for SARS-CoV-2 assess only antibody responses. Despite the growing evidence that T cells play a crucial role in protection, especially against emerging viral variants, no routine test is available to determine T cell immunity. The prognostic value of SARS-CoV-2-specific antibodies for determining whether individuals are immune and protected against disease remains uncertain. This is in part due to the following: (a) specificity and limitations such as the sensitivity of antibody tests, and (b) the lack of correlation between antibody titers (quantity) and the antiviral function of antibodies (quality). Approximately a quarter of SARS-CoV-2-infected patients with …

Uncovering The Pml::Rara Fusion In Cytogenetically Cryptic And Fish-Negative Acute Promyelocytic Leukemia-A Case Report And Comprehensive Literature Review, Busra Delikkaya, Jaime Eberle-Singh, Arianna Morton, Jerald Gong, Jinglan Liu

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

The PML::RARA fusion resulting from t(15;17) is the genetic hallmark of acute promyelocytic leukemia (APL), typically detected by cytogenetics and/or fluorescence in situ hybridization (FISH) studies. Rarely, APL patients present with normal cytogenetics and FISH findings, complicating diagnosis and delaying life-saving therapy. We report a 23-year-old male with clinical, morphologic and immunophenotypic features consistent with APL but negative for FISH studies. Despite prompt initiation of all-trans retinoic acid (ATRA) based on clinical suspicion, the patient succumbed to intracranial hemorrhage. Quantitative reverse transcriptase PCR (qRT-PCR) confirmed a long isoform PML::RARA fusion. A review of 34 published cytogenetics- and FISH-negative cases since …

Land Struggles, Resistance, And Mutual Protection Along The Colorado-New Mexico Border: The Sacred Right Of Self-Preservation, José A. Rivera Ph.D

Faculty Publications

Mutual protection societies proliferated in the American Southwest during a period of rapid social change, 1870-1930, coincident with significant changes in the region’s political economy and increased competition for land and water resources. To resist encroachment and protect their natural resources, hispano communities in Colorado and New Mexico organized mutual benefit and protective associations known as mutualistas, with a large number concentrated in the San Luis Valley of Colorado as well as in many rural counties of northcentral New Mexico. The Costilla Valley of New Mexico is a prototypical hispano settlement initially established as part of the expansive Sangre …

Bay Staters Believe Healey Deserves Re-Election, Oppose Immigration Crackdown In Boston 9/29/2025, Unh Survey Center

All UNH Survey Center Polls

Just over half of Massachusetts residents approve of the job Governor Maura Healey has done and say that she deserves to be re-elected. Many Republican primary voters are largely undecided about the candidate they want to face Healey. In the race for U.S. Senate from Massachusetts, less than half of Bay Staters believe incumbent Ed Markey deserves to be re-elected. Most Massachusetts residents feel safe in Boston, support Boston's immigration policies, and oppose the increased deployment of federal personnel to enforce immigration policies in the city. Majorities support a limit on annual rent increases and Massachusetts officials coordinating with other …

Economics Of Corneal Cross-Linking For Keratoconus Treatment, Christopher J. Rapuano, Richard L. Lindstrom, Eric Donnenfeld, John P. Berdahl, Vance Thompson, David Kratochvil, John Carter

Wills Eye Hospital Papers

AIM: To optimize the real-world applicability of a health economic model estimating the cost-effectiveness of corneal cross-linking for the treatment of keratoconus in the United States.

MATERIALS AND METHODS: A previously reported discrete-event simulation (DES) model was adapted to reassess the cost-effectiveness of corneal cross-linking (CXL) from the US payer perspective. The simulation of keratoconus progression, which is a key driver of model outcomes, was remodeled to more accurately reflect the real-world relationship between age and the rate of disease progression. All costs were updated to reflect 2025 values. We simulated 4,000 eyes of 2,000 patients diagnosed with keratoconus to …

Draft Final 2025 Residential Metals Abatement Program (Rmap): Cccs Gymnasium Soil Remedial Action Work Plan (Rawp), Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Glucodensity Functional Profiles Outperform Traditional Continuous Glucose Monitoring Metrics, Marcos Matabuena, Rahul Ghosal Ph.D., Javier Enrique Aguilar, Ayya Keshet, Robert Wagner, Carmen Fernández Merino, Juan Sánchez Castro, Vadim Zipunnikov, Jukka-Pekka Onnela, Francisco Gude

Faculty Publications

Continuous glucose monitoring (CGM) data have revolutionized the management of type 1 diabetes, particularly when integrated with insulin pumps to mitigate clinical events such as hypoglycemia. Recently, there has been growing interest in utilizing CGM devices in clinical studies involving healthy and diabetic populations. However, efficiently exploiting the high temporal resolution of CGM profiles remains a significant challenge. Numerous indices—such as time–in–range metrics and glucose variability measures–have been proposed, but evidence suggests these metrics overlook critical aspects of dynamic glucose homeostasis. As an alternative method, this paper explores the clinical value of glucodensity metrics in capturing glucose dynamics—specifically the speed …

Mapeo De La Accesibilidad De Datos De Organizaciones No Lucrativas En Países De América Latina: Primeras Perspectivas De Un Estudio Comparativo Exploratorio, Angie Holzer, Tania Hernandez, Ted Gray Barnes Jr, Noah Ellis, Sumasri Jasti, Hannah Chu, Evan Campione, Louis Ye, Nithin Kumar, Quoc Thai Dinh

Journal of Nonprofit Innovation

Este artículo presenta los hallazgos de un estudio global sobre la accesibilidad de datos de organizaciones no lucrativas, centrado en México y en otros países de América Latina. El análisis explora si existen bases de datos de organizaciones no lucrativas, quién las opera, qué barreras de accesibilidad están presentes, qué requisitos deben cumplir las organizaciones no lucrativas para registrarse, y qué costos de registro enfrentan. Utilizando un diseño comparativo exploratorio, el estudio destaca tanto las similitudes como las diferencias entre países, situando los sistemas de datos de organizaciones no lucrativas dentro de teorías más amplias de transparencia, rendición de cuentas …

Serum Endotrophin Relates To Blood Pressure In Young South Asian Women But Not White Women: Evidence Of Ethnic Variation In Its Early Vascular Implications, Ravi Retnakaran, Dawei Bu, Jiajie Pu, Philip W Connelly, Anthony J Hanley, Ningyan Zhang, Zhiqiang An, Bernard Zinman, Philipp E Scherer

The Brown Foundation: Institute of Molecular Medicine

BACKGROUND: Endotrophin is a novel circulating fibroinflammatory protein that has recently been associated with cardiovascular disease (CVD) and all-cause mortality. However, little is known about its role early in the natural history of vascular disease nor whether it exhibits ethnicity-specific variation. Recognizing that South Asians have an elevated risk of ultimately developing CVD, we sought to address these questions by characterizing endotrophin and its physiologic correlates in young South Asian women as compared to White women.

METHODS: From a cohort recruited in pregnancy and followed to 1-year after delivery, we identified 40 participants of South Asian descent and 40 age- …

The Rider (2025-09-29), Daniela Martinez Salazar

The Rider Archives

Vol. 11, No. 5

Amicus Brief In Support Of Ross Intelligence In Ross Intelligence V. Thomson Reuters, Jess Miers, Bryan L. Frye, Mateusz Blaszczyk

Akron Law Faculty Publications

This amici curiae brief, filed in Thomson Reuters Enterprise Centre GmbH and West Publishing Corp. v. ROSS Intelligence Inc. before the U.S. Court of Appeals for the Third Circuit, argues that Thomson Reuters failed to state a viable claim for copyright infringement against ROSS Intelligence. The amici—law professors specializing in copyright and technology—contend that Westlaw’s headnotes are uncopyrightable factual summaries of judicial opinions and that the West Key Number System has long been in the public domain. The brief distinguishes between AI “pretraining” and “fine-tuning,” emphasizing that ROSS’s fine-tuning process relied on expert-created materials rather than wholesale copying. It cautions …

Genome-Wide Association Study And Genome Prediction Of Tallness Trait In Spinach Phenotyping, Ibtisam Alatawi, Haizheng Xiong, Hanan Alkabkabi, Kenani Chiwina, Beiquan Mou, Qun Luo, Yuejun Qu, Renjie Du, Awais Riaz, Derrick J. Harrison

Horticulture Faculty Publications and Presentations

Plant height is a critical agronomic trait in spinach (Spinacia oleracea L.), influencing both mechanical harvesting efficiency and overall yield. In this study, plant height variation was evaluated in 307 United States Department of Agriculture (USDA) germplasm accessions, which were phenotyped and genotyped using 15,058 single-nucleotide polymorphisms (SNPs) obtained from whole-genome resequencing. A genome-wide association study (GWAS) was conducted using the General Linear Model (GLM), Mixed Linear Model (MLM), Multiple Loci Mixed Model (MLMM), Fixed and Random Model Circulating Probability Unification (FarmCPU), and Bayesian-information and Linkage-disequilibrium Iteratively Nested Keyway (BLINK) models implemented in the Genomic Association and Prediction Integrated Tool …

Approval Of Mckee Remains Low In Ri, Few Likely Democratic Primary Voters Back Him Against Foulkes 9/29/2025, Unh Survey Center

All UNH Survey Center Polls

Seven in ten Rhode Islanders disapprove of Governor Dan McKee's job performance, including six in ten Democrats. Many cite his handling of infrastructure or transportation or his leadership as the reason for their disapproval. Looking ahead to 2026, only one in six believe McKee deserves re-election. Prospective voters in the Democratic primary prefer former CVS executive Helena Foulkes, though half remain undecided. In the 2026 race for the U.S. Senate, half of Rhode Islanders think incumbent Jack Reed deserves re-election and Reed is popular among likely primary voters. On state issues, majorities support Rhode Island working with other Northeast states …

ความรับผิดทางแพ่งของบริษัทแม่ต่อผู้เสียหายที่ได้รับผลกระทบจากพื้นที่ปนเปื้อนสารอันตรายของบริษัทลูก (Parent Company’S Civil Liability To Victims Affected By A Subsidiary’S Hazardous Substance Contaminated Site), Patthanith Promarak

Chulalongkorn University Law Journal

งานวิจัยนี้มีวัตถุประสงค์เพื่อศึกษาความรับผิดทางแพ่งของบริษัทแม่ต่อผู้เสียหายที่ได้รับผลกระทบจากพื้นที่ปนเปื้อนสารอันตรายของบริษัทลูก โดยเป็นการศึกษาวิจัยเอกสารจากบทบัญญัติกฎหมาย คำพิพากษาศาล หนังสือตำรา และบทความเชิงวิชาการที่เกี่ยวข้อง ทั้งในประเทศและต่างประเทศ ผลการศึกษาพบว่า ปัจจุบันพระราชบัญญัติส่งเสริมและรักษาคุณภาพสิ่งแวดล้อมแห่งชาติ พ.ศ. 2535 ยังไม่มีบทบัญญัติให้บริษัทแม่เข้ามารับผิดชอบในความเสียหายจากพื้นที่ปนเปื้อนสารอันตรายของบริษัทลูก หากบริษัทแม่มีส่วนร่วมในแหล่งกำเนิดมลพิษหรือกำกับดูแลบริษัทลูก แต่ขาดการยึดถือแหล่งกำเนิดมลพิษทางกายภาพหรือเจตนาเพื่อตนอย่างใดอย่างหนึ่งไป อันไม่ครบองค์ประกอบของการเป็นผู้ครอบครองที่ต้องรับผิดตามมาตรา 96 หากบริษัทแม่มีการกระทำที่ไม่คำนึงถึงความเป็นนิติบุคคลของบริษัทลูกที่ไม่ใช่การกระทำละเมิด หากแต่เป็นการใช้โครงสร้างความเป็นนิติบุคคลของบริษัทลูกในทางมิชอบ อันได้แก่ การใช้นิติบุคคลเป็นเครื่องมือเพื่อหลบเลี่ยงหรือรับหน้าที่หรือความรับผิด และการมีทรัพย์สินปะปนกัน ดังนั้น จึงสมควรกำหนดบทบัญญัติที่เกี่ยวกับความรับผิดของบริษัทแม่ภายใต้พระราชบัญญัติดังกล่าว เพื่อให้ผู้เสียหายในคดีมลพิษจะได้รับความเป็นธรรมในการเยียวยา

ปัญหาของการตีความข้อยกเว้นด้านความมั่นคงตามมาตรา Xxi(B) ขององค์การการค้าโลก (Issues With The Interpretation Of Security Exceptions Under Article Xxi(B) Of The World Trade Organization), Nitinun Leethanakul

Chulalongkorn University Law Journal

บทความวิจัยนี้ศึกษาพัฒนาการของการตีความมาตรา XXI(b) ขององค์การการค้าโลก (WTO) เกี่ยวกับข้อยกเว้นด้านความมั่นคง ตั้งแต่ยุค GATT จนถึงปัจจุบัน โดยวิเคราะห์แนวปฏิบัติและคำวินิจฉัยในการยกอ้างข้อยกเว้นนี้ ผลการศึกษาพบว่า ในยุค GATT และ WTO ตอนต้น การตีความมาตรา XXI ยังขาดความชัดเจน โดยมีการอ้างอิงข้อยกเว้นนี้น้อยมาก และในกรณีที่มีการอ้างอิง ส่วนใหญ่มักยุติด้วยการเจรจา ตกลงกันโดยไม่ผ่านกระบวนการวินิจฉัยที่จะก่อให้เกิดบรรทัดฐานหรือแนวปฏิบัติ อย่างไรก็ตาม นับตั้งแต่ยุคสงครามการค้า การอ้างอิงข้อยกเว้นนี้ตามมาตรา XXI(b) ได้แพร่หลายมากขึ้น และคณะกรรมการวินิจฉัยข้อพิพาทแห่ง WTO ได้แสดงแนวโน้มที่ชัดเจนยิ่งขึ้นในหลายประเด็น เช่น การให้รัฐใช้ดุลพินิจในส่วนของบทนำและเป็นอำนาจพิจารณาของคณะกรรมการวินิจฉัยข้อพิพาทในบทเฉพาะ การแบ่งองค์ประกอบของบทบัญญัติและการตีความ “ผลประโยชน์สำคัญในด้านความมั่นคง” แต่ยังคงมีประเด็นที่ไม่ชัดเจน โดยเฉพาะในเรื่องการตีความ “สถานการณ์ฉุกเฉินในความสัมพันธ์ระหว่างประเทศ” และขอบเขตการใช้ดุลพินิจของรัฐที่จะถูกตรวจสอบโดยคณะกรรมการวินิจฉัยข้อพิพาท

Plasmonic Nanoparticle Integration On Fiber Optic: Role Of Organic Linker And Functionalization Length In Refractive Index Sensing, Shela Ilmiyah, Mohamad Syahadi, Muflikhah Muflikhah, Yuwana Pradana, Zainul Arifin Iman Supardi, Iwan Darmadi, Lia Aprilia

Makara Journal of Science

Nanoplasmonic fiber optic sensors leverage the optical fiber’s inherent compactness and surface sensitivity via evanescent-field interactions with the localized surface plasmon resonance of the metallic nanoparticles. One of the popular approaches is self-assembly owing to its relatively low cost. Despite its low cost, the self-assembly technique has low reproducibility and exhibits low sensitivity because of low nanoplasmonic coverage on the fiber optic surface. In this study, several fabrication techniques were explored to assess the refractive index sensitivity by comparing three common organosilanes, i.e., (3-Aminopropyl)triethoxysilane (APTES), (3-Aminopropyl)trimethoxysilane, and (3-Mercaptopropyl)trimethoxysilane. Comparative analyses assessed the anchoring efficiency of the three silanes, sensor reproducibility, …

Adsorption Of Cu(Ii) Ions From Aqueous Solutions Using A Magnetite Biochar Composite Material, Widi Aprilia Ta'bi, Paulina Taba, Abdul Wahid Wahab, Maming Gappa, Muhammad Zakir, Nur Umriani Permatasari

Makara Journal of Science

Water contamination from heavy metals, such as Cu(II) ions, poses severe threats to human health and the environment. This necessitates the development of efficient and eco-friendly treatment methods. In this study, a magnetite–biochar composite (MBC) was developed as an effective adsorbent for reducing Cu(II) ions from liquid waste. Biochar was produced through the pyrolysis of water hyacinth at 500 °C, while magnetite was synthesized using FeSO₄·7H₂O and FeCl₃·6H₂O with molar ratio of 1:2. The MBC was formed using a co-precipitation method and characterized by Fourier transform Infrared (FTIR) spectroscopy, X-ray diffraction (XRD), Brunauer–Emmett–Teller, and vibration sample magnetometer instruments. FTIR analysis …

Quantifying The Decay Timescale Of Volcanic Sulfur Dioxide In The Stratosphere, Paul A. Nicknish, Kane Stone, Susan Solomon, Simon Carn

Michigan Tech Publications

The injection of sulfur dioxide (SO2) into the stratosphere and its subsequent oxidation to form sulfate aerosols after large volcanic eruptions can have profound effects on Earth's climate. The removal of volcanic SO2 in the stratosphere is thought to be driven by its gas-phase oxidation by the hydroxyl radical (OH); once oxidized, it goes on to form sulfate aerosols. However, it has also been suggested that heterogeneous oxidation on ash could also be important or even dominant, which would imply the faster removal of SO2 and thus the faster formation of aerosols, at least in ash-rich plumes. Additionally, recent work …

Real-World Use Of Classic And Non-Classic Psychedelics In Hispanic/Latino Adults With Obsessive-Compulsive Disorder: International Findings From The Latino Study, David S Mathai, Jill O Robinson, Kevin Wagner, Logan Neitzke-Spruill, Dayan Berrones, Jacey L Anderberg, Renee M Frederick, Vanessa Zavala Cruz, Josselyn S Muñoz, Latin American Trans-Ancestry Initiative For Ocd Genomics, Brazilian Obsessive-Compulsive Spectrum Disorder Working Group;, Carolyn I Rodriguez, Lynnette A Averill, James J Crowley, Eric A Storch, Amy L Mcguire

Center for Medical Ethics and Health Policy Staff Publications

Objective: Despite growing research on the potential mental health benefits of psychedelics, there has been limited study of these drugs in populations with obsessive-compulsive disorder (OCD) and with Hispanic and Latin American (H/L) ancestry.

Methods: Demographic and clinical assessments were conducted as part of the Latin American Trans-ancestry Initiative for OCD genomics (LATINO) Study in H/L participants with OCD living throughout the Americas. Self-reported data on the prevalence of naturalistic psychedelic use and associated outcomes on OCD symptoms were collected in a subsample of 2,639 adults. Descriptive statistics and regression analyses were used to assess psychedelic use, predictors of use, …

Artificial Intelligence-Enabled Automated Analysis Of Transmission Electron Micrographs To Evaluate Chemotherapy Impact On Mitochondrial Morphology In Triple Negative Breast Cancer, Argenis Arriojas, Mokryun L Baek, Mariah J Berner, Jiaqi Wang, Joseph Duraisingh, Alexander Zhurkevich, Antentor Othrell Hinton, Matthew D Meyer, Lacey E Dobrolecki, Michael T Lewis, Kourosh Zarringhalam, Gloria V Echeverria

Faculty, Staff and Students Publications

Advancements in transmission electron microscopy (TEM) have enabled in-depth studies of biological specimens, offering new avenues to large-scale imaging experiments with subcellular resolution. Mitochondrial structure is of growing interest in cancer biology due to its crucial role in regulating the multi-faceted functions of mitochondria. We and others have established the crucial role of mitochondria in triple-negative breast cancer (TNBC), an aggressive subtype of breast cancer with limited therapeutic options. Building upon our previous work demonstrating the regulatory role of mitochondrial structure dynamics in metabolic adaptation and survival of chemotherapy-refractory TNBC cells, we sought to extend those findings to a large-scale …

Functional Outcomes In Pediatric Patients On Renal Replacement Therapy In A Worldwide Registry, Kristin J Dolan, Katja M Gist, Abby Basalely, Gabriella Bottari, Abhishek Chakraborty, Mihaela Damian, Dana Fuhrman, Denise C Hasson, Catherine Joseph, Dave Kwiatkowski, Susan Martin, Jenn Nhan, Nicolas Ollberding, David T Selewski, Danielle Soranno, Michelle C Starr, Amy Strong, Sameer Thadani, Huaiyu Zang, Ayse Akcan Arikan

Faculty, Staff and Students Publications

Background and hypothesis: Mortality rates of children supported with continuous renal replacement therapy (CRRT) have improved, yet morbidity remains high. We aimed to evaluate the functional outcomes of children receiving CRRT using Functional Status Scale (FSS). We hypothesized that children receiving CRRT will have worse FSS compared with their baseline and acquire new morbidity at hospital discharge and 6 and 12 months post-discharge, and that lack of renal recovery will contribute to worsening functional status.

Methods: This is a retrospective chart review from The Worldwide Exploration of Renal Replacement Outcomes Collaborate in Kidney Disease (WE-ROCK), an international multi-center registry. Twenty-eight …

Psychiatry Of Intellectual Disability In The Uk: Looking Back, Moving Forward, Rohit Shankar, Richard Laugharne

Peninsula Medical School

In this century, psychiatry for people with intellectual disability in the United Kingdom has undergone profound shifts, shaped by deinstitutionalization, legislative reform, a focus on psychotropic reduction, an increasing recognition of the premature mortality, and a growing recognition of rights-based, person-centred approaches. Despite progress, entrenched challenges remain, including fragmented services, inconsistent outcome measures, inappropriate psychotropic prescribing, and health inequalities. The coming decades promise transformative opportunities through genomics, digital health, and personalized interventions, through integrated management of co-occurring conditions, but risk deepening inequities if inclusion is not intentional. This paper synthesizes past developments, including the impact of abuse scandals, legal reforms, …

Current States In Understanding Oligodendroglia-Mediated Neurological Issues In Neurofibromatosis Type 1 (Nf1), Benjamin E Aghoghovwia, Cheng-En Shen, Sabiha Bano, Nandini Shyamala, Alesandra Echeandia Marrero, Khushboo Irshad, Samer Sharafaldin, Nicole M Brossier, Yuan Pan

Faculty, Staff and Student Publications

Neurofibromatosis type 1 (NF1) is among the most common neurogenetic disorders and is associated with an increased risk of developing tumors in the nervous system. Additionally, up to 80% of patients with NF1 experience neurological complications, including deficits in attention, memory, and executive function. Significant effort has been dedicated to studying how NF1 mutations autonomously dysregulate neuronal function. Increasing evidence indicates that NF1 mutations also dysregulate the oligodendroglial lineage that contributes to neurological issues in NF1. Here, we summarize our current understanding of how NF1 mutations impact the oligodendroglial lineage homeostasis and plasticity. We also discuss gaps in knowledge, potential …

Habeas Mentem: Revisiting Sufficiency-Of-Counsel Standards In Post-Aedpa Habeas Corpus Proceedings, Alejandra S. Alvarez

Florida Law Review

The Antiterrorism and Effective Death Penalty Act of 1996 (AEDPA) has contributed to long-standing complexities in our understanding of habeas corpus and its function as a device for judicial inquiry into the constitutionality of imprisonment. Since its passage and subsequent interpretations by Congress and the courts, criminal defendants have faced heightened challenges in seeking federal review of their state convictions. The United States Supreme Court has yet to recognize a concrete right to counsel for post-conviction proceedings--during which most criminal defendants file their habeas petitions claiming, for example, ineffective assistance of trial counsel-meaning that a large number of defendants file …

Allowing The Tree To Be Cut Down: Quo Warranto Writs In Florida, John W. Wilcox

Florida Law Review

There is no sense in declaring that an action is outside someone's scope of power after the action has already occurred. In much the same way, it does not matter whether someone may chop down a tree after the tree is down. Yet, the Florida Supreme Court's interpretation of the quo warranto writ in League of Women Voters of Florida v. Scott allows the figurative tree to be cut down and then later declares it should have been protected.

Indigenous People Integration Into National Climate Decision Making Process, Omnia Ahmed Ayoub Ahmed

COP30

Our policy paper here is going to explore the urgent need to recognise and enhance the participation and integration of indigenous communities in global climate cases and discussions in decision making processes , despite their contribution now….we are focusing on their case now because they are the most Affected by its impacts , due to their strong connection to natural eco systems , their traditional knowledge and their practices are essential for the biodiversity conservation and sustainable resource management but , unfortunately there was a systemic exclusion due to some factors and limiting and representation in in climate conferences such …

The Formalisation Of The Judiciary In The International Climate Governance Vis-À-Vis A Solution For The Accountability Gap In Political Institutions, Shristi Gautam

COP30

The international governance of climate change has historically been led by political institutions operating under multilateral frameworks, such as the UNFCCC and the Paris Agreement. Under these frameworks, the mitigation ambition and implementation of NDCs remain subject to state discretion, with no binding consequences for non-compliance, creating an enduring enforcement deficit. The paper examines the increasing judicialization of climate governance as a means of addressing this deficit, positioning the judiciary as an active enforcer rather than a passive adjudicator. Drawing on Urgenda v. The Netherlands, Leghari v. Pakistan, Milieudefensie v. Royal Dutch Shell, and the 2025 ICJ Advisory Opinion, the …

Association Of Estimated Plasma Volume Status With Invasive Hemodynamics And Adverse Clinical Outcomes In Patients With Pulmonary Hypertension And Chronic Kidney Disease, Andrew Geller, Jose Manuel Martinez Manzano, Esteban Kosak Lopez, Phuuwadith Wattanachayakul, John Malin, Raul Leguizamon, Tara John, Rasha Khan, Ian Mclaren, Alexander Prendergast, Simone Jarrett, Kevin Bryan Lo, Christian Witzke

Einstein Health Papers

Identifying noninvasive measures to assess intravascular volume status and risk stratify patients with pulmonary hypertension (PH) and chronic kidney disease (CKD) is needed. We assessed the predictive value of estimated plasma volume status (ePVS) using the Strauss-derived Duarte formula in PH-CKD patients. This single-center retrospective cohort analysis included patients with PH and CKD Stage 3b (CKD3b), Stage 4 (CKD4), or Stage 5 (CKD5) who underwent right heart catheterization from 2018 to 2023. Patients were categorized into low ePVS (< 6.2) and high ePVS (≥ 6.2) using Youden's J statistics. We used the Cox-proportional hazards model, adjusting for age, sex, and body mass index, to investigate the association between …

Ole Miss Business School Honors 10 Alumni, Tina H. Hahn

University of Mississippi News

OXFORD, Miss. – The School of Business Administration at the University of Mississippi has honored business giants and innovators by inducting them into the second class of its Hall of Fame.

Evaluation Of Image Quality In Mobile Cone-Beam Ct With Dose Modulation Using Automatic Exposure Control: A Phantom Study, Keita Okazaki, Wenchao Cao, Reza Taleei, Firas Mourtada, Jun Li, Karen Mooney, Pramila Rani Anne, Yingxuan Chen

Department of Radiation Oncology Faculty Papers

BACKGROUND: The integration of mobile cone-beam computed tomography (CBCT) into brachytherapy workflows offers clinical advantages such as immediate verification of applicator placement and adaptive treatment planning. These benefits require sufficient image quality to delineate applicators, target volumes, and organs at risk. A systematic evaluation of automatic exposure control (AEC) settings, radiation dose, and image quality is essential to ensure clinically acceptable imaging while minimizing patient exposure.

PURPOSE: This study evaluates the characteristics of AEC and its impact on image quality and radiation dose in a mobile CBCT system used for brachytherapy.

METHODS: The Elekta ImagingRing CBCT system was used to …