Digital Commons Network^™

Teaching Swimming To Children With Disabilities: A Qualitative Analysis Of Swim Instructorstea, Stephanie S. Garcia-Hidalgo, Martin E. Block

International Journal of Aquatic Research and Education

When teaching children with disabilities, swim instructors need to be able to assess the unique strengths and needs of each child to determine modifications needed to instruction, equipment, and the setting and then be flexible enough to make changes in real-time to ensure success for the child. Unfortunately, many swim instructors only work seasonally and have the occasional child with a disability, and as a result are likely to have limited training and experiences with children with disabilities. The purpose of this pilot qualitative study is to examine backgrounds, training, and experiences of six swim instructors who work with children …

Promising Practices For Increasing The Number Of Equity-Owed Lifeguards In Canada And The United States Of America, Sofia Pantano, Audrey R. Giles

International Journal of Aquatic Research and Education

Currently a shortage of lifeguards exists in Canada and the United States (US) (Frommer, 2023; Santucci, 2024), and those who are working as lifeguards often do not reflect the diversity of the communities they serve (Martinez, 2020). Increasing the number of lifeguards from equity-owed groups is a potential way of increasing the lifeguard workforce and decreasing the shortage of workers in these important roles, as well as a moral imperative. In this paper I explore challenges to and promising practices aimed at increasing the representation of members equity-owed groups in lifeguarding. I begin with an overview of lifeguarding in Canada …

Sociology Between The Gaps Volume 10 (2025)

Sociology Between the Gaps: Forgotten and Neglected Topics

No abstract provided.

Reliability Targeted Snow Loads And Winter Wind Parameters For Locations Outside Of The Conterminous United States, Brennan L. Bean, Nicholas Brimhall, Bikram Bhusal, Marc Maguire, Maha Moussa

Browse all Datasets

The national building standard ASCE 7 moved to reliability-targeted snow loads (RTSLs) in the 2022 version. This necessitates the development of RTSLs for international locations. This repository contains the data and code needed to produce RTSLs and Winter Wind Parameters for locations outside of the Conterminous United States (OCONUS). It relies on annual maximum snow loads provided in a separate data release (see Brimhall et al. 2025).

October 15, 2025 Faculty Senate Minutes, University Of South Carolina

Faculty Senate

No abstract provided.

Evidence And Learning Forum: Improving The Measurement Of Social And Gender Norms Change In The Practice Of Fgm, Esther Lwanga Walgwe, Chi-Chi Undie, Dennis Matanda, Stella Muthuri, Francis Obare

Sexual and Reproductive Health, Rights, and Choices

The November 2024 Evidence and Learning Forum: Improving Measurement of Social and Gender Norm Change in the Practice of FGM brought together over 80 participants representing program officers, socio-behavioral experts and scientists from 10 countries in East, West and North Africa. Hosted by the FGM Data Hub in partnership with UNICEF, UNFPA, and WHO, the two-day forum was geared toward sharing and examining tools and approaches, successful strategies, and challenges in measuring shifts in social and gender norms surrounding FGM.

The meeting objectives were to: 1) Review and assess the progress made in developing and using valid measures for evaluating …

College Of Liberal Arts Faculty Bylaws 2025-2026, College Of Liberal Arts Faculty, Rollins College

College of Liberal Arts Bylaws

No abstract provided.

U.S. Water Infrastructure: Diving Into Needs And Recent Policy Developments, Joseph Kane

Brookings Scholar Lecture Series

As part of the Brookings Scholar Lecture Series, Brookings Mountain West presents a lecture titled, "U.S. Water Infrastructure: Diving Into Needs and Recent Policy Developments" by Brookings fellow in Brookings Metro, Joseph Kane. Whether providing drinking water, treating wastewater, or managing stormwater, water infrastructure in the United States spans a wide range of human-made and natural systems. In turn, the enormous scale and variety of these systems is leading to an array of challenges: aging and vulnerable infrastructure; fragmented governance and siloed planning across different geographies; a lack of financial, technical, and managerial capacity; difficulties adapting to new industrial and …

Alejandro Handal V. Innovative Industrial Properties Inc

2025 Decisions

USDC for the District of New Jersey

Miguel Robles Corcuera V. Attorney General United States Of America

2025 Decisions

Agency

Hydralazine Inhibits Cysteamine Dioxygenase To Treat Preeclampsia And Senesce Glioblastoma, Kyosuke Shishikura, Jiasong Li, Yiming Chen, Nate R. Mcknight, Thomas P. Keeley, Katelyn A. Bustin, Eric W. Barr, Snehil R. Chilkamari, Mahaa Ayub, Sun Woo Kim, Zongtao Lin, Ren-Ming Hu, Kelly Hicks, Xie Wang, Donald M. O'Rourke, J. Martin Bollinger, Zev A. Binder, William H. Parsons, Kirill A. Martemyanov, Aimin Liu, Megan L. Matthews

SKMC Student Presentations and Publications

Hydralazine (HYZ), a treatment for preeclampsia and hypertensive crisis, is listed by the World Health Organization as an essential medicine. Its mode of action has remained unknown through its seven decades of clinical use. Here, we identify 2-aminoethanethiol dioxygenase (ADO), a key mediator of targeted protein degradation, as a selective HYZ target. The drug chelates ADO's metallocofactor and can alkylate one of its ligands. The resultant inactivation stabilizes regulators of G protein signaling (RGS4 and RGS5) that ADO normally marks for proteolysis, explaining the drug's vasodilatory activity and comporting with observations of diminished RGS levels in both clinical preeclampsia and …

Large Language Models As Information Providers For Appropriate Antimicrobial Use: Computational Text Analysis And Expert-Rated Comparison Of Chatgpt, Claude And Gemini, Marcello Di Pumpo, Maria Rosaria Gualano, Danilo Buonsenso, Francesca Raffaelli, Daniele Donà, Vittorio Maio, Patrizia Laurenti, Walter Ricciardi, Leonardo Villani

College of Population Health Faculty Papers

OBJECTIVES: Antimicrobial resistance is a critical public health threat. Large language models (LLMs) show great capability for providing health information. This study evaluates the effectiveness of LLMs in providing information on antibiotic use and infection management.

METHODS: Using a mixed-method approach, responses to healthcare expert-designed scenarios from ChatGPT 3.5, ChatGPT 4.0, Claude 2.0 and Gemini 1.0, in both Italian and English, were analysed. Computational text analysis assessed readability, lexical diversity and sentiment, while content quality was assessed by three experts via DISCERN tool.

RESULTS: 16 scenarios were developed. A total of 101 outputs and 5454 Likert-scale (1-5) scores were obtained …

Lecture Series To Feature Exonerated Man Once On Death Row, Marisa C. Atkinson

University of Mississippi News

OXFORD, Miss. – A survivor of wrongful conviction and nearly 30 years on Alabama's death row, Anthony Ray Hinton will share his story as part of the University of Mississippi's Dr. Jeanette Jennings Lecture Series on Oct. 21.

Estrogen-Related Receptor Alpha Promotes Skeletal Muscle Regeneration And Mitigates Muscular Dystrophy, Thi Thu Hao Nguyen, Ya Xiang Huang, Svitlana Poliakova, Citu Citu, Eira Mann, Danesh H Sopariwala, Zhongming Zhao, Ashok Kumar, Vihang A Narkar

The Brown Foundation: Institute of Molecular Medicine

Skeletal muscle regeneration in chronic muscle diseases such as Duchenne Muscular Dystrophy (DMD) has remained clinically unsurmountable. Estrogen‐related receptor alpha (ERRα) plays a critical role in adult skeletal muscle metabolism and exercise fitness. Whether ERRα activation can drive muscle regeneration and mitigate dystrophy in DMD is not known. We have investigated ERRα signaling in pre‐clinical models of acute muscle injury and DMD. ERRα is induced in differentiating C2C12 myoblast and regenerating muscle. ERRα silencing suppressed proliferation and differentiation in C2C12 myoblasts. RNA sequencing revealed that angiogenic factor and proliferation genes were downregulated by ERRα knockdown in proliferating cells, whereas oxidative …

Introducing Mcodegpt As A Zero-Shot Information Extraction From Clinical Free Text Data Tool For Cancer Research, Kai Zhang, Tongtong Huang, Bradley A Malin, Travis Osterman, Qi Long, Xiaoqian Jiang

Faculty, Staff and Student Publications

Background: The vast amount of natural language clinical notes about patients with cancer presents a challenge for efficient information extraction, standardization, and structuring. Traditional NLP methods require extensive annotation by domain experts for each type of named entity and necessitate model training, highlighting the need for an efficient and accurate extraction method.

Methods: This study introduces a tool based on the Large Language Model (LLM) for zero-shot information extraction from cancer-related clinical notes into structured data aligned with the minimal Common Oncology Data Elements (mCODE™) structure. We utilize the zero-shot learning capabilities of LLMs for information extraction, eliminating the need …

The College Voice, Vol. 62, No. 7 [October 15, 2025], Connecticut College

2025-2026

No abstract provided.

China’S Turn To Domestic-Led Growth: Replacing Consumption Taxes With Land Taxes?, Yilin Hou, Michael Kumhof, Lei Shao

Center for Policy Research

As part of its turn towards domestic-led growth China plans to stimulate consumption, including through a reduction in consumption taxes. We compare two model-based scenarios in which the revenue losses from lower consumption taxes are replaced by higher income taxes or higher land taxes. The model is carefully calibrated to recent Chinese data, including detailed fiscal data. We find that higher income taxes lead to significant losses in output and incomes, while higher land taxes lead to significant gains. These gains are increasing in the share of land in net wealth, a statistic for which better data would be invaluable.

Evaluation Of Hypolipidemic And Hypoglycemic Effects Of Dillenia Indica L. On Alloxan-Induced Diabetic Rats, Md Mahfuj Alam Siddiq

Student Scholarship

Context: Dillenia indica L. a tropical fruit-bearing plant native to South and Southeast Asia, has attracted scientific interest due to its rich phytochemical composition and potential therapeutic benefits in managing diabetes, lipid disorders, and oxidative stress. Objective: The objective of this study was to investigate the potential antidiabetic and lipid-lowering properties of D. indica fruit and bark extracts in a rat model of alloxan-induced type 2 diabetes. Methods: Diabetes was induced in rats using an intraperitoneal injection of alloxan (160 mg/kg) after a 12-hour fast. The chloroform fractions of D. indica fruit and bark (200 mg/kg) were administered intraperitoneally, with …

Front Matter, Editors Of Osgoode Hall Law Journal

Osgoode Hall Law Journal

Volume 62, Number 1

Mortal Writing: Toward Braver Concepts Of “Better Writers,” Peerness, And Nationality, Enrique Paz, Annalee Roustio

The Writing Center Journal

Reflecting on experiences with two Afghan students writing in response to events following the U.S. withdrawal from Afghanistan in 2021, this essay challenges traditional writing center practices in response to the evolving and urgent writing needs of diverse (international) student populations. Focusing on the intersectional identities of student writers and the geopolitical realities they face, we develop further the call to transform writing centers into “brave spaces.” Deploying this framework of bravery, we call for a reevaluation of the concept of “better writers,” of empathy constructed primarily through peerness, and of the current conceptualization of nationality in writing center scholarship. …

“I (Still) Need Help On Many Things”: A Writing Center Replication Study Of First-Generation College Students’ Writing Challenges And Cultural Capital, Red Douglas, Ashley Cerku, Isabelle Lundin, Mary Gallagher, Xavier Iriarte, Sophia E. Williams, Kaylie Williams

The Writing Center Journal

Research has increasingly addressed first-generation (FG) students both in and outside the center (Baelemian & Feng, 2013; Bond, 2019; Denny et al., 2018; Ward et al., 2012), but there remains a need to address this unique student population from the perspective of critical theory. In a replication study of Bond’s 2019 “‘I Need Help on Many Things, Please’: A Case Study Analysis of First-Generation College Students’ Use of the Writing Center,” we examined the needs and perceptions of self-reported FG students in a writing center at a large, regional, public R2 university in the Midwest. We gathered preexisting digital data …

Indiana At A Glance: County Trends, 2025 Edition, Roberto Gallardo

Purdue University Press Books

Indiana at a Glance: County Trends, 2025 Edition provides an overview of macro socioeconomic and demographic trends based on county-level data in ten-year periods in Indiana, the upper Midwest region, and the nation. Analyzing data primarily from 2013 through 2023, this book presents information that contextualizes the design and implementation of specific policies enacted by elected officials and community leaders, and reveals the impact these initiatives have on the public.

Inspired, in part, by the United States Department of Agriculture’s Rural America at a Glance reports, as well as the author’s more than twenty years of work in the field, …

Graphrag-Enabled Local Large Language Model For Gestational Diabetes Mellitus: Development Of A Proof-Of-Concept, Edmund Evangelista, Fathima Ruba, Salman Bukhari, Amril Nazir, Ravishankar Sharma

All Works

Background: Gestational diabetes mellitus (GDM) is a prevalent chronic condition that affects maternal and fetal health outcomes worldwide, increasingly in underserved populations. While generative artificial intelligence (AI) and large language models (LLMs) have shown promise in health care, their application in GDM management remains underexplored. Objective: This study aimed to investigate whether retrieval-augmented generation techniques, when combined with knowledge graphs (KGs), could improve the contextual relevance and accuracy of AI-driven clinical decision support. For this, we developed and validated a graph-based retrieval-augmented generation (GraphRAG)–enabled local LLM as a clinical support tool for GDM management, assessing its performance against open-source LLM …

Front Matter, Georganne Nordstrom, Isaac K. Wang, Sherry Wynn Perdue

The Writing Center Journal

Front matter and introduction for Writing Center Journal 43.2.

Cerebellar Dysfunction In Glaucoma Patients, Anisha Kasi, Ji Won Bang, Vivek Trivedi, Jeannie Au, Ian Conner, Gadi Wollstein, Joel Schuman, Rakie Cham, Kevin Chan

Wills Eye Hospital Papers

Glaucoma patients often have higher injurious fall rates compared to healthy older adults. However, little is known about the underlying neural mechanisms. Recent evidence shows cerebral changes beyond the visual pathway of glaucoma patients, yet it remains unclear whether the cerebellum, which plays an important role in balance and motor control, is involved in glaucoma. In this study, we sought to investigate cerebellar functional connectivity changes in glaucoma by comparing 32 glaucoma subjects and 10 age-matched healthy control subjects who underwent resting-state functional magnetic resonance imaging at 3 Tesla with eyes closed. After conducting both regions-of-interest and seed-to-voxel analyses, we …

A Comprehensive Assessment And Benchmark Studyof Large Atomistic Foundation Models For Phonons, Md Zaibul Anam, Ogheneyoma Aghoghovbia, Mohammed Al-Fahdi, Lingyu Kong, Victor Fung, Ming Hu

Faculty Publications

The rapid development of universal machine learning potentials (uMLPs) has enabled efficient, accurate predictions of diverse material properties across broad chemical spaces. While their capability for modeling phonon properties is emerging, systematic benchmarking across chemically diverse systems remains limited. We evaluate six recent uMLPs—EquiformerV2, MatterSim, MACE, and CHGNet—on 2429 crystalline materials from the Open Quantum Materials Database. Models were used to compute atomic forces in displaced supercells, derive interatomic force constants (IFCs), and predict phonon properties including lattice thermal conductivity (LTC), compared with density functional theory and experimental data. The EquiformerV2 pretrained model trained on the OMat24 dataset exhibits strong …

The Use Of Social Prescribing And Community-Based Wellbeing Activities As A Potential Prevention And Early Intervention Pathway To Improve Adolescent Emotional And Social Development: A Systematic Mapping Review, Siobhan B. Mitchell, Lucy Cartwright, Alex Gude, Alison Bethel, Harriet Hunt, Jane R. Smith, Daniel Hayes, Marcello Bertotti, Paul Jarvis-Beesley, Vashti Berry, Kerryn Husk

Peninsula Medical School

BACKGROUND: Social prescribing (SP) initiatives which aim to connect individuals to community-based assets have received increased research and policy attention, however schemes have mostly centred on adults. There is little research examining how social prescribing might work for children and young people (CYP), and specifically, what pathways into social prescribing look like for this group.

METHODS: We conducted a systematic mapping review to understand what social prescribing pathways look like for CYP. Searches were carried out in February 2022. We reviewed published journal articles and grey literature on pathways for CYP accessing activities or services in the community. We synthesised …

Tng260 Is A Small-Molecule Corest Inhibitor That Sensitizes Stk11-Mutant Tumors To Anti-Pd-1 Immunotherapy, Leanne G Ahronian, Soumyadip Sahu, Minjie Zhang, Ayushi S Patel, Ke Geng, Reshmee Bhattacharya, Gerald S Falchook, Jonathan W Goldman, Alexander I Spira, Salman R Punekar, David R Spigel, Judy S Wang, Ferdinandos Skoulidis, Janaye Stephens, Mary Meynardie, Jaylen M Powell, Alfonso Lopez, Michela Ranieri, Magdalena A Ploszaj, Yi Jer Tan, Yeuan Ting Lee, Yi Yu, Jiehui Deng, Ting Chen, Patrick Mccarren, Alice Tsai, Suleman S Hussain, Brian Doyon, Kenjie Amemiya, Jacques Ermolieff, Preksha Shahagadkar, Nikitha M Das, Lauren R Flynn, Julie A Shields, Laney Danielczyk, Brian J Mcmillan, Andre Mignault, Samuel R Meier, Hsin-Jung Wu, David J Guerin, Douglas A Whittington, Chengyin Min, Iga Sienczylo, John P Maxwell, Heather J Dibenedetto, Hideo Watanabe, Brian B Haines, Alan Huang, Adam Crystal, Jannik N Andersen, Xinyuan Wu, Kwok-Kin Wong

Faculty, Staff and Student Publications

Patients with non–small cell lung cancer (NSCLC) with loss of the tumor suppressor gene STK11 are resistant to immune checkpoint therapies like anti–PD-1. In this study, we conducted an in vivo CRISPR screen that identified histone deacetylase 1 as a target to reverse anti–PD-1 resistance driven by loss of STK11 and developed TNG260, a potent small-molecule inhibitor of the CoREST complex with selectivity exceeding previously generated inhibitors in this class in preclinical studies. Treatment with TNG260 led to increased expression of immunomodulatory genes in STK11-deficient cancer cells. When combined with anti–PD-1, TNG260 induced immune-mediated stasis and/or regression in STK11 …

Conversion Of Failed Anatomic Total Shoulder Arthroplasty To Reverse Shoulder Arthroplasty Yields Similar Pain And Functional Outcomes To Primary Reverse Shoulder Arthroplasty But Has A Higher Baseplate Failure Rate: A Matched Cohort Study., Kevin A Hao, Trevor G Simcox, Keegan M Hones, Jonathan O Wright, Thomas W Wright, Tyler Lamonica, Bradley S Schoch, Joseph J King

Faculty, Staff and Student Publications

Background: To investigate whether patients who initially underwent anatomic total shoulder arthroplasty (aTSA) for glenohumeral osteoarthritis and were subsequently revised to reverse TSA (rTSA) due to rotator cuff failure or glenoid loosening ultimately attained a similar clinical outcome compared with those who underwent primary rTSA and identify predictors of poor outcomes in the former population.

Methods: We did a single-center retrospective review of 63 shoulders who underwent revision rTSA after primary aTSA that failed due to glenoid component loosening (n = 32), rotator cuff failure (n = 24), or recurrent instability (n = 7). Pain and functional outcomes at minimum …

Correction: Román-Ríos Et Al., Gabriel Román-Ríos, Gabriel Rosario-Ortiz, Marcos J Ramos-Benitez, Ricardo A Mosquera, Wilfredo De Jesús-Rojas

Faculty, Staff and Student Publications

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