Digital Commons Network^™

Patient Satisfaction Among Opioid Use Disorder Treatment Sample In An Opioid Treatment Program: A Mixed Method Research Study, Stanley Nkemjika

Department of Psychiatry and Human Behavior Faculty Papers

BACKGROUND/OBJECTIVES: Patient satisfaction is increasingly recognized as a key indicator of the effectiveness of substance use disorder (SUD) treatment. While some studies suggest disparities in satisfaction across treatment settings, there remains limited research examining these differences, particularly among vulnerable populations. This study aimed to assess patient perceptions of satisfaction with opioid use treatment services and explore how demographic and socioeconomic factors influence these experiences.

METHODS: Conducted between 1 February and 31 March 2025, the study took place at a longstanding Opioid Treatment Program in Philadelphia. A total of 217 participants receiving treatment were recruited through convenience sampling during routine clinic …

Quaker Campus, October 30, 2025 (Vol. 24, Issue 5), Whittier College

Quaker Campus

No abstract provided.

Local Group Galaxies From An External Perspective, Stacy S. Mcgaugh

Faculty Scholarship

I discuss Local Group galaxies from the perspective of external galaxies that define benchmark scaling relations. Making use of this information leads to a model for the Milky Way that includes bumps and wiggles due to spiral arms. This model reconciles the terminal velocities observed in the interstellar medium with the rotation curve derived from stars, correctly predicts the gradual decline of the outer rotation curve, and extrapolates well out to 50 kpc. Rotationally supported Local Group galaxies are in excellent agreement with the baryonic Tully-Fisher relation. Pressure supported dwarfs that are the most likely to be in dynamical equilibrium …

Vista: October 30, 2025, University Of San Diego

USD Vista (1965-)

No abstract provided.

Letters, Emotions And The Experience Of Separation In The Early Modern World, James Daybell

School of Law, Humanities and Social Sciences

No abstract provided.

Final Analysis Of The Resonate-2 Study: Up To 10 Years Of Follow-Up Of First-Line Ibrutinib Treatment For Cll/Sll, Jan A Burger, Paul M Barr, Tadeusz Robak, Carolyn Owen, Alessandra Tedeschi, Anita Sarma, Piers E M Patten, Sebastian Grosicki, Helen Mccarthy, Fritz Offner, Edith Szafer-Glusman, Cathy Zhou, Anita Szoke, Lynne Neumayr, James P Dean, Paolo Ghia, Thomas J Kipps

Faculty, Staff and Student Publications

With up to 10 years of follow-up, we report results from the final analysis of RESONATE- 2, a phase 3 study of first-line ibrutinib vs chlorambucil for the treatment of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL). Patients aged ≥65 years with previously untreated CLL/SLL without del(17p) were randomly assigned to receive either single-agent ibrutinib (420 mg/d; n = 136) or chlorambucil (0.5-0.8 mg/kg; ≤12 cycles; n = 133). With a median follow-up of 9.6 years in the ibrutinib arm, the median progression-free survival (PFS) was 8.9 years (95% confidence interval [CI], 7.0 to not estimable [NE]) vs 1.3 years (95% …

Disrupting Latina/X Media Representations: A Performance Art Installation Informed By Autoethnographic And Embodied Explorations, Sandra Cristina Roa

USF Tampa Graduate Theses and Dissertations

In this dissertation I use autoethnography and performance methods to create a performance art installation that examines and re-imagines the role of media representations in shaping how I as a Latina actively negotiates belonging and identifies this concept as always in a processes requiring negotiation. I argue belonging is influenced by how I see myself or don’t see myself in media representation and offer the counter-narrative as a way of asserting agency and disrupting marginalization. In this project, I tend to the tensions felt between being a community member, media maker, and qualitative researcher in order to disrupt media messages. …

Cmc Arthroplasty For Treatment Of The Painful And Arthritic Thumb: A Review Of Surgical Treatment Options With Preferred Technique, Jon E. Hammarstedt, Yehuda A. Masturov, Sebastian D. Arango, Jacob Zeitlin, Samuel H. Payne, Mark S. Rekant

Department of Medicine Faculty Papers

Arthritis of the first carpometacarpal joint is a prevalent and often disabling condition for many older adults. The diagnosis is typically established through a comprehensive patient history, physical examination, and confirmatory radiographs. Nonsurgical management with splinting and anti-inflammatory medication has demonstrated effectiveness. Several surgical options have proven effectiveness for those who fail nonsurgical management. Surgical options include silicone implantation, resection arthroplasty, tendon interposition, ligament reconstruction, denervation, and joint implant arthroplasty. In the following review, we will elaborate upon the array of therapeutic approaches, culminating in the delineation of our preferred method.

Reply To Fernández Et Al. Comment On "Goudra Et Al. Anesthesia For Bronchoscopy-An Update, Basavana Goudra, Lalitha Sundararaman, Prarthna Chandar, Michael Green

Department of Medicine Faculty Papers

No abstract provided.

A Single-Nucleus Transcriptomic Atlas Of The Adult Aedes Aegypti Mosquito, Olivia V Goldman, Alexandra E Defoe, Yanyan Qi, Yaoyu Jiao, Shih-Che Weng, Brittney Wick, Leah Houri-Zeevi, Priyanka Lakhiani, Takeshi Morita, Jacopo Razzauti, Adriana Rosas-Villegas, Yael N Tsitohay, Madison M Walker, Ben R Hopkins, Aedes Aegypti Mosquito Cell Atlas Consortium, Maximilian Haeussler, Omar S Akbari, Laura B Duvall, Helen White-Cooper, Trevor R Sorrells, Roshan Sharma, Hongjie Li, Leslie B Vosshall, Nadav Shai

Faculty, Staff and Students Publications

The female Aedes aegypti mosquito's remarkable ability to hunt humans and transmit pathogens relies on her unique biology. Here, we present the Aedes aegypti Mosquito Cell Atlas, a comprehensive single-nucleus RNA sequencing dataset of more than 367,000 nuclei from 19 dissected tissues of adult female and male Aedes aegypti, providing cellular-level resolution of mosquito biology. We identify novel cell types and expand our understanding of sensory neuron organization of chemoreceptors across all sensory tissues. Our analysis uncovers male-specific cells and sexually dimorphic gene expression in the antenna and brain. In female mosquitoes, we find that glial cells, rather than neurons, …

Longitudinal Characterization Of Males With X-Linked Creatine Transporter Deficiency: Final Results Of A Multiyear Observational Study, Judith S Miller, Cristan Farmer, Susan Blair, Simona Bianconi, Natacha Akshoomoff, Irina Anselm, Bruce A Barshop, Lindsey Becker, Amanda E Bennett, Leandra N Berry, Elizabeth M Berry-Kravis, Aleksandra Bruchey, Anna W Byars, Tricia Cimms, Kim M Cecil, Maxine Covello, Laura S Cubit, Tanvi Das, Robert J Davis, Madison Drye, Can Ficicioglu, John B Fulton, Robin P Goin-Kochel, Whitney Guthrie, Barbara E Hallinan, Fady Hannah-Shmouni, Kathryn E Gustafson, Dwight D Koeberl, Nicola Longo, Eva Mamak, Saadet Mercimek-Andrews, Claire Michalak, Forbes D Porter, Samar Rahhal, Linda Rees, Gail A Spiridigliozzi, Caitlin Stone, Nancy R Sullivan, V Reid Sutton, Rebecca P Thomas, Manisha Udhnani, Susan Waisbren, Michelle Xu, Lin Zhang, Melanie Brandabur, Audrey Thurm

Faculty, Staff and Students Publications

Background: The purpose of the Vigilan observational study (ClinicalTrials.gov, NCT02931682) was to prospectively assess the natural history and developmental course of creatine transporter deficiency (CTD).

Methods: Males with CTD aged 6 months to 65 years were evaluated at 6-month intervals for up to 4 years. Evaluations included neurodevelopmental assessments of intellectual functioning, adaptive functioning, and challenging behaviors and the onset and progression of medical comorbidities.

Results: Fifty participants (median age, 7.6 years) were enrolled. The predominant CTD phenotype consisted of significant intellectual disabilities and limited skill development over time. Most participants had a history of febrile or nonfebrile seizures, …

Cohesin Haploinsufficiency Is Tolerated In Cbfb::Myh11-Driven Murine Acute Myeloid Leukemia, Shannon E Conneely, Alexis Quezada, Kristen J Kurtz, Nenggang Zhang, Josephine De La Fuente, Nesa Mercer, Jason H Rogers, Rogelio Aguilar, Geraldo Medrano, Margaret A Goodell, Paul P Liu, Debananda Pati, Rachel E Rau

Faculty, Staff and Students Publications

Cohesin gene mutations occur in many malignancies, including acute myeloid leukemia (AML). Loss-of-function mutations in the four major cohesin complex genes (RAD21, SMC3, SMC1a, and STAG2) occur across most major genetic subtypes of AML but are notably absent in AML harboring CBFB::MYH11, suggesting that cohesin mutations yield distinct biological outcomes dependent on the genetic AML driver. We hypothesized that CBFB::MYH11-expressing leukemias would be dependent on intact cohesin genes given their near-mutual exclusivity. To investigate this, we combined either germline or inducible heterozygous deletions in cohesin genes Smc3 or Rad21, respectively, with an inducible murine model of Cbfb::MYH11 AML. This approach …

Distinct Molecular Responses Of Human Intestinal Organoids To Proton And Photon Radiation, Victoria Poplaski, Tajhal D Patel, Hoa Nguyen-Phuc, Amal Kambal, Lawrence Bronk, Mary K Estes, Cristian Coarfa, Sarah E Blutt

Faculty, Staff and Students Publications

Radiation exposure impairs rapidly renewing tissues like the intestinal epithelium, yet translational insights from murine models have been limited by species-specific responses. Here, we use human intestinal organoids (HIOs) derived from jejunal epithelium to evaluate human epithelial responses to low dose proton and photon (gamma) radiation. Gamma irradiation induces a unique developmental and metabolic shift in crypt-like organoids, including enrichment of amino acid metabolism pathways and activation of fetal-associated transcription factors and morphology. Integrated multi-omic profiling reveals serotonin biosynthesis as a central regenerative node. Human intestinal organoids can complement animal models and are emerging as a powerful tool in modeling …

From Face-To-Face To Interface: A Critical Review Of Human Relationships In The Digital Era, Zainb I. Mohammed, Lina M. Shaker

AUIQ Humanities and Social Sciences

The rise of digital technologies has significantly transformed the nature, structure, and experience of human relationships across multiple domains. This review critically examines how digital platforms such as social media, messaging applications, online dating sites, and AI-driven interfaces have reshaped interpersonal connections, including friendships, romantic relationships, and family dynamics. Drawing on interdisciplinary literature from psychology, communication studies, sociology, and media theory, the review explores themes such as digital intimacy, parasocial interactions, performative relationships, remote caregiving, and the ethics of AI-mediated emotional engagement. Special attention is given to underrepresented populations (e.g., older adults, neurodiverse individuals), as well as longitudinal and developmental …

Academic Passion As A Predictor Of Professional Ambition Among Graduate Students In Riyadh, Rasmia F. Alotaibi Dr.

International Journal for Research in Education

The current study aimed to identify the relationship between academic passion and career ambition among graduate students in Riyadh, and to identify the differences between the average scores of male and female students on the two study variables according to gender (male-female). It also aimed to identify the positive impact of academic passion on career ambition among the research sample. The study adopted a descriptive correlational approach, and was conducted on (210) students, divided into (105) male students and (105) female students from graduate studies at an academic institution in Riyadh. The tools used were the Academic Passion Scale and …

Tight Spherical Embeddings (Updated Version), Thomas E. Cecil, Patrick J. Ryan

Mathematics and Computer Science Department Faculty Scholarship

This is an updated version of the paper [14] which appeared in the proceedings of the 1979 Berlin Colloquium on Global Differential Geometry. This paper contains the original exposition together with some notes by the authors made in 2025 (as indicated in the text) that give references to descriptions of progress made in the field since the time of the original version of the paper. The main result of this paper is that every compact isoparametric hypersurface Mⁿ ⊂ Sⁿ⁺¹ ⊂ Rⁿ⁺² is tight, i.e., every non-degenerate linear height function ℓ_p, p ∈ …

Racial Identification Congruence, Ethnic Identity, And Skin Tone: Implications For Well-Being In Latinx Populations, Marisol Orea

ETD Collection

Latinx individuals often navigate complex intersections of race, ethnicity, and phenotype within a sociocultural context that imposes external racial categorizations. This dissertation examines the psychological implications of racial identification congruence—the alignment between an individual's self-identified race and how others perceive them—on life satisfaction, mental health, and minority stress. Specifically, it investigates how racial identification congruence, ethnic identity, and self-identified skin tone relate to these well-being outcomes among Latinx adults. A national sample of 509 Latinx participants completed validated measures, and data were analyzed using hierarchical regression, moderation, and mediation analyses. Ethnic identity emerged as a consistent and significant predictor of …

Flow Structure And Mixing Near A Small River Plume Front: Winyah Bay, Sc, Usa, Christopher Papageorgiou, George Voulgaris, Alexander E. Yankovsky, Diane Bennett Fribance

Faculty Publications

This study presents Eulerian data from Winyah Bay, SC, USA collected during the passage of a tidal plume. The data captured the evolution and structure of the plume and include high-resolution velocity and temperature time series, supplemented by temperature – salinity profiles from a MicroCTD profiler. The observations identified a pre-existing plume extending to 4 m, with a water density of 1023.6 kg m⁻³, laying above denser ambient waters. Upon arrival, the newly discharged tidal plume introduced a fresher layer (1020.7 kg m⁻³) extending to 2.6 m, gradually thinning due to radial spreading. The plume's frontal …

Managing Anticoagulation In A Patient With Calciphylaxis And Mechanical Valve: A Therapeutic Dilemma, Qutaiba Qafisheh, Abdalhakim Shubietah, Mohanad Qwaider, Muath A. Baniowda, Abdalrahman Assaassa, Roaa Aljunaidi, Abubakar Nazir

Division of Cardiology Faculty Papers

BACKGROUND: Calciphylaxis is a rare, life-threatening vasculopathic syndrome most commonly seen in end-stage renal disease (ESRD) and associated with high mortality. Vitamin K antagonists complicate management in patients with mechanical valves by potentially exacerbating vascular calcification while remaining essential for thromboprophylaxis.

CASE PRESENTATION: A 50-year-old woman with ESRD on hemodialysis and a mechanical mitral valve on warfarin presented with severe abdominal pain and rapidly progressive necrotic ulcers. Despite broad-spectrum antibiotics and sodium thiosulfate, lesions worsened. Biopsies were nondiagnostic; however, the clinical phenotype was consistent with calciphylaxis. A multidisciplinary team transitioned anticoagulation from warfarin to subcutaneous unfractionated heparin (UFH) (333 U/kg …

Minutes From October 29 2025, University Senate

University Senate Minutes

Minutes from October 29 2025 University Senate Meeting

Local Journalist Equivalents (Ljes) In The Mountain West, 2025, Taylor Volk, Anthony Arroyo, Yiselle Olivas Ruiz, Olivia K. Cheche, William E. Brown Jr.

Economic Development & Workforce

This fact sheet presents 2025 data on Local Journalist Equivalents (LJEs) for the Mountain West states of Arizona, Colorado, Nevada, New Mexico, and Utah. The data are derived from the Muck Rack report “Local Journalist Index 2025,” which includes data on LJEs for states and counties across the U.S. This fact sheet highlights state-level LJE data among Mountain West states, as well as LJE data for the following 17 Nevada counties: Carson City, Churchill, Clark, Douglas, Elko, Esmeralda, Eureka, Humboldt, Lander, Lincoln, Lyon, Mineral, Nye, Pershing, Storey, Washoe, and White Pine.

English, Lamia Saad Alnomei

USF Tampa Graduate Theses and Dissertations

It is crucial to integrate technologies into childhood education and teaching digital citizenship, but there are certain barriers to this integration in Saudi Arabia. Elicitation interviews were conducted in the context of this study with six participants, including kindergarten teachers and school leaders. They showed different levels of understanding the concept of digital literacy and citizenship and various levels of valuing technologies as tools for education. For instance, some expressed the need for more awareness and training, and other exhibited a deep understanding of digital citizenship. The study used Rogoff’s sociocultural theory, explored the influence of culture and parents on …

Why Aren’T More People Calling 988 For Mental Health Crises?, Michiko Ueda, Colleen M. Heflin, Yanhong Liu, Qingyi Yu, Seethalakshmi Ramanathan

Center for Policy Research

When someone is in a mental health crisis, calling 911 has long been the default response. However, 911 call centers are not well-equipped to handle mental health emergencies, and law enforcement dispatch can result in unnecessary arrests, hospitalizations, or crisis escalation. The 988 Suicide and Crisis Lifeline launched in 2022 is a free, confidential alternative, yet awareness remains low and misconceptions persist. Using data from a 2024 national online survey of nearly 1,900 U.S. adults ages 18-50, this brief summarizes findings about awareness of 988, willingness to use it, and concerns about the service. Results show that only 22% of …

Focus, 2025, Summer, Andrews University

Focus

FOCUS (ISSN 1077-9345) is published quarterly, free of charge, for alumni and friends of Andrews University, an institution owned and operated by the Seventh-day Adventist Church.

Sexual Activity And Functioning After Breast Cancer Treatment: Perspectives On The Importance Of Pleasure From A Radiotherapy Cohort, Melanie Besculides, Lauren Carney, Ksenia Gorbenko, Sheryl Green, Melissa Brito, Jezelle Lynch, Carly Feldman, Cindy Munoz, Madhu Mazumdar, Deborah C. Marshall

Student Papers, Posters & Projects

BACKGROUND: Breast cancer affects millions of women and while treatment can be lifesaving, it also has numerous side effects, including those related to sexual function, which often impact the ability to experience pleasure from sex. This study aimed to understand how breast cancer survivors define sexual activity, identify important aspects, and ascertain perceived impacts of treatment on sexual activity and function, particularly related to pleasure.

METHODS: Semi-structured interviews were conducted with women who were breast cancer survivors at least one-year post-radiation. Priority populations were oversampled (racial/ethnic/sexual/gender minorities, those aged over 65 or under 45). The sample included 23 participants: 11 …

A Life Less Difficult, Jennifer L. Holberg

University Faculty Publications and Creative Works

Last week I had the opportunity to speak on a faculty panel to our university’s Board of Trustees. Our topic: shared governance. Perhaps your eyes are already glazing over. So, before you scroll away, I want to reassure you that that won’t be the focus of today’s contribution.

Long-Term Liver-Targeted Aav8 Gene Therapy For Mucopolysaccharidosis Iva, Shaukat A. Khan, Eliana Benincore-Florez, Fnu Nidhi, Jose Victor Álvarez, Dione A. Holder, Shunji Tomatsu

Department of Pediatrics Faculty Papers

Mucopolysaccharidosis IVA (MPS IVA) is a lysosomal storage disease with an autosomal recessive trait caused by the deficiency of N-acetylgalactosamine-6-sulfate sulfatase (GALNS) enzyme, which leads to the accumulation of chondroitin-6-sulfate and keratan sulfate, primarily in cartilage and its extracellular matrix, resulting in a direct impact on cartilage and bone development, as well as subsequent systemic skeletal dysplasia. ERT and HSCT are current treatment options, but they have a limited effect on bone lesions. In this article, we investigated liver-specific AAV8 vectors with a thyroxine-binding globulin promoter in the MPS IVA murine model to evaluate the long-term (24 weeks in males …

Flow Structure And Mixing Near A Small River Plume Front: Winyah Bay, Sc, Usa, Christopher Papageorgiou, George Voulgaris, Alexander E. Yankovsky, Diane Bennett Fribance

Faculty Publications

This study presents Eulerian data from Winyah Bay, SC, USA collected during the passage of a tidal plume. The data captured the evolution and structure of the plume and include high-resolution velocity and temperature time series, supplemented by temperature – salinity profiles from a MicroCTD profiler. The observations identified a pre-existing plume extending to 4 m, with a water density of 1023.6 kg m⁻³, laying above denser ambient waters. Upon arrival, the newly discharged tidal plume introduced a fresher layer (1020.7 kg m⁻³) extending to 2.6 m, gradually thinning due to radial spreading. The plume's frontal …

Scrotal Temperature Change During Running In Naked Humans, Yasuho Takii, Makoto Fukuda, Kazuyuki Kanosue, Tamae Yoda

Children’s Nutrition Research Center Staff Publications

Male reproductive organs are functionally affected by high body temperature. This study aimed to clarify the thermoregulation mechanisms of the human scrotum during running, and experiments were conducted to investigate temperature changes in the whole body and the scrotum. Eleven male long-distance runners performed treadmill running at 60%[Formula: see text] for 60 min in an indoor environment at 27 °C and 40% relative humidity. Immediately after the start of the run, the skin temperatures in areas other than the scrotum decreased or showed a tendency to decrease. In contrast, the scrotal temperature increased immediately after the start of the run. …

Streamflow Reconstruction For The Upper Indus Basin, Syeda Saria Bukhary, Sajjad Ahmad

Civil and Environmental Engineering and Construction Faculty Research

The sustainability of water resources in Pakistan faces mounting challenges due to population growth, climate change, and declining groundwater reserves. The Indus River, vital for the country’s agriculture, energy, and economy, suffers from limited instrumental discharge records that do not capture long-term hydrologic variability or extreme flow events. This study addressed this gap by developing streamflow reconstructions for the Upper Indus Basin (UIB) using tree-ring chronologies (TRC) combined with sea surface temperature (SST) data—an approach not previously applied in this region—for four discharge stations: Partab, Daniyor, Besham Qila, and Kachora. Stepwise linear regression models using TRC and SST predictors explained …