Therapeutic Potential Of Hookworm Proteins In Promoting Regulatory Immune Responses To Modulate Trypanosoma Cruzi Induced Liver Inflammation And Oxidative Stress, Maria Jose Villar, Cristina Poveda, Bin Zhan, Maya Gonsoulin, Kathryn M Jones

Faculty, Staff and Students Publications

Background: Chronic Trypanosoma cruzi infection causes significant liver pathology, and current antiparasitic treatments often worsen hepatic damage. Hookworm-derived proteins have shown immunomodulatory effects in inflammatory diseases, including T. cruzi-induced myocarditis.

Objective: This study evaluates recombinant hookworm proteins AIP-1 and AIP-2 for treating liver inflammation in a murine model of chronic Chagas disease (CD).

Methods: Female BALB/c mice infected with T. cruzi were treated with AIP-1 or AIP-2 (1 mg/kg) for seven days. Controls were untreated or received aspirin (25 mg/kg) for 14 days. Liver tissues were analyzed for parasite burden (quantitative polymerase chain reaction - qPCR), histopathology (H&E, Picrosirius Red), …

Molecular Heterogeneity Of Hpv-Associated Cancers And Strategies To Overcome Treatment Resistance, Sara Rasouli, Weiyi Gong, Raegan Wood, Danyal Daneshdoust, Anam Khan, Rani Mahyoob, Chongwen Cao, Zihao Yu, Nagireddy Putluri, Gennady Shvets, Haichang Li, Bo Zhao, Xuefeng Liu, Jenny Li

Faculty, Staff and Students Publications

Human papillomavirus (HPV) is a major driver of global cancer incidence, responsible for nearly all cervical cancers and a significant proportion of oropharyngeal, anal, and other anogenital cancers. Despite the availability of effective vaccines, HPV-associated cancers persist due to persistent infection, immune evasion, and the virus's ability to integrate into the host genome, contributing to molecular heterogeneity and therapeutic resistance. Here, we summarize molecular heterogeneity and the emerging combined therapeutic strategies. High-risk HPV types, notably HPV16 and HPV18, initiate carcinogenesis through persistent infection of epithelial basal cells and through the actions of the E6 and E7 oncoproteins, which disrupt the …

Δnp63 Defines An Exocrine-Committed Subset Of Murine Pancreatic Progenitor Cells, Katarina Coolens, Melissa Van Der Vliet, Jente Van Campenhout, Natalia Del Pozo, Alejo Torres-Cano, Catharina Olsen, Jianming Xu, Rose-Anne Romano, Heiko Lickert, Meritxell Rovira, Isabelle Houbracken, Jonathan Baldan, Francisco X Real, Francesca M Spagnoli, Ilse Rooman

Faculty, Staff and Students Publications

No abstract provided.

Injectable Borate/Borosilicate Bioactive Glass Systems For The Regeneration Of Hard Tissue – A Critical Review Of The Literature, S. Sina Mohammadi, Sunjeev S. Phull, Ryan J. Gilbert, Mark R. Towler

Chemical and Biochemical Engineering Faculty Research & Creative Works

Bone defects caused by trauma, infection, or tumor resection remain difficult to treat because successful repair requires both structural restoration and control of the local pathological microenvironment. Osteolysis, defined as pathological bone resorption, is central to many of these conditions and is commonly driven by excessive osteoclast activity. Clinically translated injectable products such as NovaBone® Putty demonstrate the value of moldable bioactiveglass grafts for defect filling; however, conventional silicate bioactive glasses are permanent and provide limited therapeutic ion release. This limitation has motivated the development of injectable borate bioactive glass (B-BGs) and injectable borosilicate bioactive glass (BS-BG) systems as more …

Effect Of Complex Alloying Elements On Oxide Scale Formation And Water-Jet Descaling Performance On Continuously Cast Low-Carbon Steels, Tochukwu P. Ojiako, Tsvetkov Dmitry, Mario Buchely, Haiming Wen, Simon N. Lekakh, Ronald J. O'Malley

Materials Science and Engineering Faculty Research & Creative Works

The formation and evolution of oxide scale in contact with mold flux during continuous casting, subsequent reheating, and hydraulic descaling are strongly governed by steel chemistry. To elucidate the effect of complex alloying elements (Si, Mn, and Cr), two industrially produced continuously cast low-carbon steel grades for manufacturing stamped parts (a base and alloyed steel grade) were investigated. The objective was to determine how alloying elements influence oxidation behavior, scale morphology, interfacial adhesion, and water-jet descaling efficiency. Continuously cast slab specimens were subjected to controlled thermal and atmospheric oxidation cycles simulating multistage industrial practice. Three initial surface conditions (industrial as-cast, …

A Method For Determining A True National Statistical Distribution Of Building Element U-Values And Its Application To A Dataset Underpinning A Building Stock Energy Model, C. Ahern, Bernard Enright, A. Griffin, B. Norton

Research Outputs: 2025-Present

The presence of default U-values in Energy Performance Certificate (EPC) databases disrupts the natural variability in measured U-value distributions. Default values, often used by assessors when empirical data is unavailable, introduce deterministic artefacts into datasets, creating artificial peaks that obscure underlying statistical patterns. This study examines the impact of these default values and identifies appropriate statistical models – Lognormal, Gamma and Normal – for measured U-values in Ireland’s national EPC dataset, comprising 463,582 dwellings. Lognormal and Gamma distributions aligned better with the central peaks, while the Normal distribution more accurately captured the tails. Although no single distribution perfectly fits the …

Water-Efficient Concrete Curing Using Sap-Infused Nonwoven Blankets: Material Screening And Performance Evaluation, Feras Kafiah, Omar K. Omar, Dr Hani Alkhatib

Research Outputs: 2025-Present

Concrete curing under hot-weather exposure requires sustained surface moisture while minimizing repeated waterapplication. This study develops and evaluates a two-layer external curing blanket comprising a polyethylene (PE) top sheetand a superabsorbent polymer (SAP)-infused needle-punched nonwoven polyester layer. Ten PE sheets, three sodiumpolyacrylate SAP grades, and three nonwoven fabrics were screened sequentially according to optical transmittance, SAPmorphology and absorption behavior, fabric absorptivity, SAP-fiber integration, and qualitative seven-day surface-wetnessobservations. The selected configuration (S7 PE/SAP 3/GT-80) was then demonstrated using a 1 × 2 m2 outdoor prototypeand compared with conventional wet burlap curing. The blanket-cured concrete produced a numerical mean core strengthof 36.5 …

5 "Povero Napoleone" Or The End Of Napoleon, Ilaria Serra

Andante: Chapter 1 The Napoleonic Era

Music for this section

Cover art: Napoleon sitting by Anonymous, Museo Poldi Pezzoli in Milano

Masculine Devotion And Moral Decay: The Paradox Of Chivalry In Malory's Le Morte Darthur, Julia Annunziato

Graduate Studies Theses and Dissertations 2026

This thesis investigates how, within Sir Thomas Malory’s Le Morte Darthur, the concept of chivalry as a literary construct is misunderstood and misrepresented by the knights who attempt to uphold it. Through a close reading of Le Morte, this paper concludes that Malory presents chivalry not as a coherent moral code, but as a paradoxical system that both promotes and undermines the values it claims to uphold. While chivalry is typically meant to emphasize honor, loyalty, and spiritual devotion, Malory’s narrative reveals how these ideals are compromised by structures of masculine competition, performative identity, homosocial desire, and corrupted …

Entre Dos Mundos: A First-Generation Cuban American's Journey Through Identity And Memory, Alessandra M. Gonzalez

Graduate Studies Theses and Dissertations 2026

ENTRE DOS MUNDOS (translated as “between two worlds”) explores the complexities of growing up as the eldest daughter in a Cuban American immigrant family and the tensions of navigating life between cultures. Set in Miami, the collection blends lyrical and prose poetry to examine cultural identity, diaspora, intergenerational memory, and the emotional landscape of young adulthood. Through personal narrative and historical context, ENTRE DOS MUNDOS traces the speaker’s coming-of-age amid the inherited stories of her family’s escape from Cuba and the lingering effects of displacement. The section “Yo” focuses on the psychological challenges of adolescence and early adulthood, reflecting on …

Lucha Libre: Legends Of The Mask, Anthony J. Aguilar

Graduate Studies Theses and Dissertations 2026

Lucha libre, also known as Mexican wrestling, is a cultural phenomenon whose history dates to 1933. Every wrestling match pits flamboyantly costumed and masked wrestlers (luchadores), classified as either the good guys (técnicos) or the bad guys (rudos), against each other in choreographed and dramatized battles. Although lucha libre is often seen as campy or “low brow” due to its exaggerated, theatrical style, this perception overlooks the deeper cultural significance and narrative potential inherent in the form. This thesis will explore the cultural evolution of lucha libre as a highly interactive themed ride attraction. By integrating guest participation through custom …

In The Walls, Taylor S. Arnold

Graduate Studies Theses and Dissertations 2026

In the Walls is a collection of short and flash fiction that uses gothic and speculative elements to explore isolation, identity, gender roles, and experiences of women, including pressures of conformity and the persistent draw of the domestic. In “Poltergeist,” a scorned ghost discovers her supernatural abilities when her husband brings home a new woman. “Home For Sale,” an experimental story structured as a Zillow listing, contains the tale of a housewife’s psychological unravelling amid paranormal encounters in her family’s new home. The titular story, “In the Walls,” focuses on a woman who attempts to conform to a homemaker role …

Un Lugar A Donde No Puedo Volver: Perteneciendo En La Distancia, Alberto J. Alonso

Graduate Studies Theses and Dissertations 2026

“A Place I Cannot Return To: Distance and Belonging” investigates how home is not limited to a fixed place, but instead a reconstruction sustained through memory and longing, which focuses on personal experiences of being away from Puerto Rico. I contribute to this broader dialogue by offering a deeply personal perspective shaped by the complexities of cultural belonging. Through photography, collage, and painting, my art practice reconstructs fragmented visual narratives of lived experience to explore homesickness, nostalgia, and displacement, examining how personal and shared histories become anchors to what continually slips away. Although I can physically return to Puerto Rico, …

Wormfood, Susan Mesler-Evans

Graduate Studies Theses and Dissertations 2026

A collection of seven fiction short stories focused on death and mortality, with genres represented including horror, fantasy, science fiction, and literary. The stories include an ecological epistolary narrative set in the near-future, a modern retelling of Hamlet, a Biblical flood narrative, a polyphonic retelling of the Bluebeard myth, a realist drama about abuse and healing, a darkly comic story of a woman planning for her own death, and a sci-fi story about two robots defying their programming to save a flower from destruction.

Teoría Y Creatividad. La Literatura Como Herramienta Educativa En El Aprendizaje Moderno De Textos Clásicos En El Idioma Español, Isabel D. Simon

Graduate Studies Theses and Dissertations 2026

In the following master’s thesis, literature is studied as an educational tool in the modern learning of classical texts in the Spanish language from both theoretical and creative perspectives. The theoretical framework to be used is based on the hermeneutic theory of Jean Grondin. The study is divided into three chapters, each focusing on a different literary piece. First, the medieval period is examined through Poema de Mio Cid (Cantar de Mio Cid) of anonymous authorship. In the second chapter, the Golden Age is analyzed through Don Quijote de la Mancha by Miguel de Cervantes. In the closing …

Passenger Pigeons, Dodos, Neanderthals, Jordan Alexander

Graduate Studies Theses and Dissertations 2026

Passenger Pigeons, Dodos, Neanderthals is a short story collection rooted in Afrofuturism and Southern literature. Passenger Pigeons centers the experiences of queer Black American women in various settings, from Mars to rural Florida. The title story of the collection follows Teri, a human on Mars, attempting to integrate into a society of Martians who exoticize and tokenize her. In this story, I use science fiction as a vehicle to confront the microaggressions and overt racism people of color often experience in professional environments. “Rather Be the Devil,” is a fabulist story detailing the character Man’s journey to find his missing …

The Role Of Cultural Intelligence In Hotel Employee Engagement, Self-Efficacy, Job Satisfaction, Performance, And Intent To Stay, Meaad Eid F Almotairi

Graduate Studies Theses and Dissertations 2026

This research examined how Cultural Intelligence enhanced hotel employees’ engagement, self-efficacy, job satisfaction, performance, and intent to stay. CQ was defined as an individual’s capability to understand, adapt to, and work effectively in culturally diverse situations. This thesis utilized a quantitative methodology based on the Job Demands–Resources (JDR) model and self-efficacy theory. The study focused on the hospitality industry in Saudi Arabia, where increasing diversity has created a need for stronger cross-cultural skills among employees. Data were collected from hotel employees and managers to examine the relationships between CQ and key employee outcomes. The findings indicated that Cultural Intelligence significantly …

Using Inferences From Natural Language Narratives To Improve Video Question Answering, Hoang Bao Truong

Graduate Studies Theses and Dissertations 2026

The purpose of this thesis is to examine how structured narrative representation and reasoning strategies jointly affect the performance of Video Question Answering (VideoQA). Although recent advances in large multimodal and language models have improved video description and retrieval, causal and counterfactual reasoning remain challenging. This thesis studies an inference-only pipeline in which videos are converted into natural-language narratives, and those narratives may optionally be transformed into a structured NarrativeML format before multiple-choice questions are answered without task-specific fine-tuning. NarrativeML is a machine-readable narrative representation that explicitly encodes entities, events, and their causal and temporal relations. Three representational contexts are …

Navigating Liminality: Building Resources For And With Undocumented Students, Yaneyry Delfin Martinez

Cal Poly Humboldt theses and projects

Rooted in Community-Based Participatory Research (CBPR) and Liberation Sociology, this project outlines an institutional blueprint for the resources and support systems needed to address the lived realities of undocumented students at Cal Poly Humboldt (CPH). Conducted during the second Trump Administration amidst escalating hostility towards immigrants and attacks on DEI initiatives, this work documents both the structural conditions shaping undocumented students’ lives and the collective resistance that emerged in response. Furthermore, it examines how immigration policy, access to and restrictions on federal and state aid, geographic conditions, and on-campus barriers reproduce and maintain legal liminality within higher education. Grounded in …

Decolonizing Restorative Justice: A Teaching Development Project, Lacy Felice Mitchell

Cal Poly Humboldt theses and projects

The coloniality of power serves as a central axis within the matrix of domination that characterizes global capitalist modernity, as Anibal Quijano famously argued. This power is rooted in particular ways of looking, seeing, and understanding social reality, anchored in Eurocentrism as an epistemological paradigm for the hegemonic discourse produced by the West against both internal and external categories of “other.” Such categories still inform the production of knowledge in educational settings. In this project, I engage in a critique of the coloniality of power to explore its implications and potential for critical pedagogical practice within the context of sociology …

Rethinking Belonging In First-Year Student Support: A Mixed-Methods Evaluation Of Eop/Sss Programing At Cal Poly Humboldt, Elizabeth Rose Silver

Cal Poly Humboldt theses and projects

This mixed-methods project examines the role of the Educational Opportunity Program and Student Support Services (EOP/SSS) first-year orientation programs, particularly STEM Summer Bridge, in supporting feelings of belonging and persistence. While institutional efforts often frame student success through metrics such as retention and concepts like sense of belonging, this project interrogates how these are experienced and understood by students themselves. Quantitative analyses compared one-year persistence rates between STEM Summer Bridge participants and multiple comparison groups across three cohorts (2022–2024). Results showed no statistically significant differences in persistence; however, STEM Summer Bridge participants demonstrated persistence rates comparable to or slightly higher …

Taking A Seat In The Circle: Decolonizing Gender Roles That Argue Against The Participation Of Feminine Bodies At The Big Drum, Juli Suzukawa

Cal Poly Humboldt theses and projects

The origins of the Big Drum can be traced back to the 1860s when Tail Feather Woman, a Dakota woman, had a vision of its creation as a tool of resistance. The Big Drum has since expanded and can now be seen at various Indigenous ceremonies and social events. However, there has been controversy regarding the participation of feminine and queer bodies. While reasons for this vary, it has also contributed to harm amongst Indigenous youths that have a more fluid stand on gender identity and may not conform to colonial “gender norms”. In this paper, I will explore how …

Endocranial Lesions: A Paleopathological Study Of Late Medieval Skeletal Remains From Żelewo Poland, Francesca Aleen Meyer

Cal Poly Humboldt theses and projects

The site of Żelewo is located in a rural area of northwestern Poland, a region historically known as Pomerania. Skeletal remains from the cemetery associated with the archaeological site Żelewo 1-3, dating mostly to the 13th-15th centuries, are likely associated with a nearby Cistercian monastery. Numerous individuals from this site show evidence of endocranial lesions. To evaluate potential factors associated with the lesions, a differential diagnosis was performed based on macroscopic observations of endocranial lesion morphology and distribution. This study takes into account estimated age at death, biological sex, and other signs of pathology in the body. Potential confounding factors, …

The Rise Of Global Collaboration In China Policy Research: Evidence From Bibliometric Network Analyses, 2000–2025, Yu Xiao, Aaron Ley, Ping Xu

Political Science Faculty Publications

This study examines the evolution of China policy research and its growing role in global policy scholarship. Using bibliometric and social network analyses of 326 articles published in 20 high-impact political science journals from 2000 to 2025, we trace the field’s expansion, identify key thematic concentrations, and document the emergence of robust international collaboration patterns. Cross-national co-authorship networks reveal a clear transition from a fragmented, Western-centered structure to a dual-hub system anchored by Mainland China and the United States, while institution-level networks show that leading Chinese universities have become central collaborators and Hong Kong institutions continue to serve as critical …

Perceptions Of Georgia Elementary School Administrators Toward Elementary Agricultural Education, Addie Tucker

Murray State Theses and Dissertations

Elementary agricultural education (EAE) is a growing component of K-12 agricultural education, yet limited research exists on how school leaders perceive its value. The purpose of this study was to explore the perceptions of Georgia elementary school administrators regarding the implementation and value of EAE programs. Specifically, this study examined elementary principals’ and district superintendents’ views on the benefits, effectiveness, and value of EAE. A descriptive research design was used. Georgia elementary principals and district superintendents with active EAE programs during the 2025-2026 academic year were surveyed in the fall of 2025. The sample consisted of 18 principals and 18 …

Identifying The Knowledge And Skills That Students Enrolled In Agricultural Systems Technology Degree Programs Need: Perspectives From University Faculty, Jerry Blake Kennedy

Murray State Theses and Dissertations

National trends have highlighted the need for a knowledgeable, skilled workforce in advanced agricultural systems. University-level Agricultural Systems Technology (AST) undergraduate degree programs and closely-related degree programs are vital to equipping the agricultural workforce with the knowledge and skills needed to support the industry. Ensuring that AST curricula are relevant and appropriate is vital to equipping undergraduate students in such programs with the knowledge and skills they need to succeed in the modern agricultural workforce. This study sought to identify the essential knowledge and skills needed by undergraduate AST degree program students from the perspectives of university-level faculty across the …

Speaking For The Families: Organizational Socialization Of Military Spouses In Volunteer Leader Positions, Virginia Klaus

Murray State Theses and Dissertations

Military spouses holding volunteer leadership positions in military unit family readiness groups, provide a link between commanders and families of service members. They act within military organizations as the only official voice of spouses, a stakeholder group recognized as influential in retention rates and force readiness. Despite their importance, military spouses are often portrayed in research as passive members, taking on roles to meet the expectations of their peers and military organizations. That contradicts historical evidence of military spouses as active organizational members who have socialized other spouses, and as family advocates who have challenged military organizational practices and policies. …

The Effect That Positive And Negative Self-Concepts Have On Adolescents' Behavior And Personalities, Portia L. Davis

Murray State Theses and Dissertations

Abstract

The development stage of adolescence is a complex process in which adolescents begin to explore their identity and form either a positive or negative self-concept. Self-concept plays a crucial role in shaping adolescents' personalities and behaviors. Self-concept includes how adolescents view themselves and how others see them. An adolescent's self-concept can influence their self-confidence, social relationships, and decision-making abilities. This study examines the relationship between overall self-concept and adolescents' personality traits and behaviors. To gather this information, a quantitative research design is used, in which adolescents complete assessments such as the Tennessee Self-Concept Scale (TSCS), the Woodcock-Johnson IV (WJ-IV), …

Personality Assessment Inventory Profiles In Adults Seeking Autism Spectrum Disorder Assessment, Emily Kinsey

Murray State Theses and Dissertations

The current study aimed to examine differences in interpersonal functioning and response validity among adults presenting for autism spectrum disorder (ASD) assessment compared to those seeking services for other clinical concerns. The study used archival data from 238 client files collected in an outpatient clinical setting. Interpersonal functioning was assessed using the Dominance (DOM), Warmth (WRM), and Nonsupport (NON) subscales of the Personality Assessment Inventory (PAI; Morey, 1991). Response validity was evaluated using the Negative Impression Management (NIM) and Positive Impression Management (PIM) scales. A multivariate analysis of variance (MANOVA) showed no significant group differences across DOM, WRM, and NON …

Soil Nutrient Sufficiency Versus Plant Nutrient Status In Compost-Amended Soils: Plant Tissue Analysis As A Diagnostic Tool, Chandralekha Joga Miss

Murray State Theses and Dissertations

This study evaluated whether Mehlich III soil nutrient sufficiency ratings reliably predict plant nutrient status and chlorophyll response across contrasting compost application histories. A greenhouse pot experiment was conducted with Chijimisai (Brassica rapa) planted in three treatment soils that had no compost (T1), moderate compost history (T2), and long-term hog manure compost application (T3). Plant performance was assessed through weekly shoot length and chlorophyll content (SPAD) measurements, leaf number at maturity, and leaf tissue nutrient analysis conducted at harvest. Soil test results indicated adequate to high nutrient levels across all three treatments. Leaf tissue analysis, however, revealed substantial …