Digital Commons Network^™

Gastrointestinal Histology Of Systemic Sclerosis: A Systematic Review, Aidan K Strother, Robert M Anderton, Naveen Kalavar, Ali Y Ayla, Tracy Ashby, Amanda Mayer, Roshan Dongre, Francesco Bonomi, Silvia Bellando Randone, Michael Hughes, Zsuzsanna H Mcmahan

Library Staff Publications

Objective: To systematically review and synthesize the histological findings of gastrointestinal (GI) tissue in patients with systemic sclerosis (SSc), aiming to clarify the role of fibrosis and other pathological processes in SSc-related GI disease.

Methods: A comprehensive literature search was conducted across MEDLINE (OVID), Web of Science, and Cochrane Library databases for studies published in English from 1960 to 2025. Inclusion criteria required studies to report qualitative histological findings from GI tissue (esophagus to anorectum) in adult SSc patients, excluding those with overlapping autoimmune diseases or malignancy. Data extraction and appraisal were performed independently by multiple reviewers.

Results: Of 1697 …

Stories From Former Foster Youth College Graduates: The Positive Impact Of K-12 Schooling And Related Educational Policy, Amanda Moon, Kristen D. Seay

Faculty and Staff Publications

Youth in foster care face disproportionate challenges when it comes to education and personal well-being. Many studies use a deficit lens when evaluating these challenges. In contrast, this study is asset-based, centering first-person accounts from five former foster youth college graduates. Using a counter-narrative framework, we conducted semi-structured interviews with participants to reveal key supports in K-12 schooling participants believed helped them achieve academic and life milestones. These were relationships with teachers and coaches, access to extracurricular activities, and literacy-rich environments. We also reviewed 11 relevant federal educational policies to identify provisions and implementation needs that aligned with participant experiences. …

Where Do Latinos Live In The New York City Metropolitan Area? Changing Settlement Patterns, 2000 - 2024, Laird W. Bergad

Center for Latin American, Caribbean, and Latino Studies

This report shows that between 2000 and 2024, the Latino population of the New York metropolitan area increased by 48% from 3,592,542 to 5,316,472 according to the U.S. Census Bureau. Along with population expansion, there was a decisive change in settlement patterns among all Latinos, which, in fact, began before 2000. This was the decline of New York City as the major area of the Latino population concentration, although there were differentiations by nationality.

In 2000, 60% of all Latinos in the region lived in the City. By 2024, this had declined to 46%. And while the City’s Latino population …

Volume Cxlv, Number 10, January 23, 2026, Lawrence University

The Lawrentian

No abstract provided.

2025 Highlights In Non-Invasive Neurostimulation And Neuromodulation For Headache Management, Chai Ching Ng, Hsiangkuo Yuan

Department of Jefferson Headache Center Papers and Presentations

No abstract available

A Universal Of Human Social Cognition: Children From 17 Communities Process Gaze In Similar Ways, Manuel Bohn, Julia Christin Prein, Agnes Ayikoru, Florian M. Bednarski, Ardain Dzabatou, Michael C. Frank, Annette M.E. Henderson, Joan Isabella, Josefine Kalbitz, Patricia Kanngiesser, Dilara Keşşafoğlu, Bahar Köymen, Maira V. Manrique-Hernandez, Shirley Magazi, Lizbeth Mújica-Manrique, Julia Ohlendorf, Damilola Olaoba, Wesley R. Pieters, Sarah Pope-Caldwell, Katie Slocombe, Robert Z. Sparks, Jahnavi Sunderarajan, Wilson Vieira, Zhen Zhang, Yufei Zong, Roman Stengelin, Daniel B.M. Haun

School of Psychology

Theoretical accounts typically assume that key features of human socio-cognitive development are universal. This paper reports a large-scale cross-cultural study (17 communities, diverse ethnicities, N = 1,377, 709 female, mean = 5.50 years, -collected March 2022 to January 2024) on gaze following in early childhood. To test for universality, cognitive processing signatures were derived from a computational model treating gaze following as social vector estimation. Results showed substantial variation between communities and individuals. Yet, the processing signature was found in all communities. Individual differences in performance were related to children's familiarity with the data-collection device but not opportunities for social …

Communication Disorders Graduate Student: Perspective Of Voice, Maycie Brentney Terrell / Blankenship

Student Theses and Dissertations

This study examined the influence of training in SPEAK OUT!® on the perceptual ratings of voice and speech made by communication disorders (CD) graduate students. The purpose of this study was to investigate the influence of SPEAK OUT!® training by comparing those who have undergone SPEAK OUT!® training with those who have not. To address this, 36 participants who attend communication disorders graduate programs within the United States were recruited. Data were collected through a Qualtrics survey distributed via email and analyzed using the Statistical Package for the Social Sciences (SPSS). The findings indicate that perceptual ratings across most voice …

Investigating The Challenges That Black Female Superintendents Face While Navigating Local School Boards, Eric Dailey

Student Theses and Dissertations

For the past twenty years, Black women have increasingly ascended to the role of school district superintendent. Black female superintendents navigate education systems that were not built with them in mind creating unique challenges. The purpose of this qualitative phenomenological study was to investigate the challenges that Black female superintendents face while navigating local school boards. This study was informed by glass ceiling theory, gendered organizations theory, and a black feminist framework establishing a research base for this study’s focus. Eight Black female superintendents were interviewed using an interview protocol. This study reveals that Black female superintendents experience similar challenges …

A Phenomenological Inquiry Into Kindergarten Teacher Perceptions Of Literacy Skills, Angela Shelton

Student Theses and Dissertations

This qualitative phenomenological study explored kindergarten teachers’ perceptions of the literacy skills of students from households with limited financial resources, compared to students who attended the universal preschool program located in District A with those who did not. The study addressed three research questions: 1. How do teachers perceive the literacy skills of these students? 2. How do teachers describe their experiences teaching literacy to these students? and 3. What resources or professional development do teachers identify as helpful in supporting literacy instruction? Semi-structured interviews with kindergarten teachers were conducted and analyzed to identify common themes. Participants reported that children …

The Impact Of Bilingual Home Literacy Practices On The Emergent Literacy Skills Of Hispanic Youth, Sophie Watkins Roberts

Student Theses and Dissertations

This study examined the impact of bilingual home literacy environments (HLEs) on the emergent literacy skills of Hispanic children enrolled in an after-school program in Jonesboro, Arkansas. Thirteen Spanish–English bilingual children in kindergarten through third grade and their parents participated. Parent-reported data were collected using an adapted Spanish–English Reading Questionnaire (SER-Q), and children’s literacy skills were assessed with the Dynamic Indicators of Basic Early Literacy Skills (DIBELS) and the Spanish Reading Inventory–Second Edition (SRI-2). Descriptive and correlational analyses explored within- and cross-language relationships between HLE practices and early reading performance. Results indicated that even modest access to books and daily …

Factors Affecting Teacher Satisfaction At Two School Districts In North Carolina Post Covid-19 Pandemic, Thomas Young

Student Theses and Dissertations

The COVID-19 pandemic caused an interruption to instruction for teachers and students across the United States and left educators unsure of the future as they returned to in-person classes. This phenomenological qualitative study concluded on the lived experiences of middle school teachers in two North Carolina districts to help uncover the reasons why they are satisfied or dissatisfied with their jobs after returning to the classroom since the pandemic. Inspired by Herzberg’s Motivation-Hygiene Theory, this research investigated the extent to which working conditions influence teacher morale, retention, and job satisfaction. Fourteen teachers of various subject areas, years of experience and …

Black Swans And Safety Nets: Food Aid, Dispersal, And Eugenics In Corbin Hollow, Glenn Davis Stone, Richard K. Robinson

Southern Anthropologist

No abstract provided.

Developing A Sense Of Community In Camp Settings: Insights From Outward Bound Programs, Theresa N. Melton, Sarah Wiley

ACA National Camp Research Forum Abstracts

No abstract provided.

Half Of Granite Staters Oppose Removal Of Maduro, Trump Foreign Policy Approval Unchanged 1/23/2026, Unh Survey Center

All UNH Survey Center Polls

Approval of President Trump’s handling of foreign policy in New Hampshire remained largely unchanged in the wake of the capture of Venezuela’s President Maduro and pressure to acquire Greenland from Denmark, but is sharply divided by partisanship. Half of New Hampshire residents oppose the capture of Venezuelan President Nicholas Maduro and few support sending ground troops to occupy the country. Very few support launching a military attack on Mexico or Colombia. Four in five Granite Staters believe the United States should play a leading or major role in world affairs and should protect citizens of foreign countries facing violence but …

Vermonters Disapprove Of Trump's Foreign Policy, Believe World Views U.S. Poorly 1/23/2026, Unh Survey Center

All UNH Survey Center Polls

Vermont residents strongly oppose the decision to capture Venezuelan President Nicholas Maduro and less than one-tenth support sending ground troops to occupy the country. Vermonters also oppose occupying Greenland or launching military attacks in Mexico or Colombia. Overall, three-quarters of Vermonters oppose President Trump's handling of foreign policy and rate the reputation of the U.S. among the rest of the world as poor or very poor.

Evaluating Retreat Of The West Antarctic Ice Sheet In Marine Isotope Stage 11 (~400,000 Years Ago) Through Quantification Of Ice Rafted Debris, Natalia Freedman, Madelyn Krischer, Trevor Williams

Making Waves REU

Quantification of ice-rafted debris (IRD) is a method for characterizing past ice-sheet behavior using the sedimentary record (McKay et al., 2022). IRD is a direct property of the sediment allowing for close examination of the ice sheet in relation to glacial and interglacial stages in Earth’s history, which are designated by Oxygen-18 excursions known as Marine Isotope Stages (MIS). Interglacial MIS-11 (~400,000 years ago) is studied as a partial analog to the current warming climate (Tzedakis et al., 2022), and we can use IRD in Antarctic deep sea sediment cores from this time to gain insight into what ice retreat …

Assessing Abuse And Neglect In U.S. Nursing Homes: A Comparative Analysis Across Pre-, During, And Post-Pandemic Periods, Katherine Gane

Theses and Dissertations

Nursing homes are among the most closely regulated providers in the U.S. healthcare system, with both federal and state agencies working together to monitor care and help protect residents. The COVID-19 pandemic, however, introduced unprecedented challenges for facilities and survey agencies alike, disrupting normal operations, limiting in-person visits, and temporarily shifting regulatory priorities. The purpose of this study was to examine how these pandemic-related disruptions were reflected in the severity and reporting patterns of substantiated abuse and neglect deficiencies in U.S. nursing homes. Using publicly available data from the Centers for Medicare & Medicaid Services (CMS), this study analyzed 39,607 …

Multilevel Analysis Of The Food And Physical Activity Environment And Adult Obesity Across U.S. Counties And States, Ann Mary Abraham, Michael D Swartz, Alexandra E Van Den Berg, Stephen H Linder

Faculty, Staff and Student Publications

Adult obesity rates have risen steadily across the United States over the past decade, with more than 40% of adults affected. Persistent geographic and demographic disparities exist in obesity prevalence across the nation. While prior research has examined individual or environmental associated factors of obesity, limited studies have addressed both physical activity and food environments across the nation using multilevel approaches. This cross-sectional ecological study (2014-2024) used a two-level random intercept model to assess the association between county- and state-level factors and adult obesity prevalence across over 3000 U.S. counties nested within 51 states. County-level associated factors included food insecurity, …

2026-01-23 Minutes Of The Executive Committee Of The Academic Senate Senate, University Of Dayton. Academic Senate. Executive Committee

ECAS Minutes

Approved minutes of a meeting of the Executive Committee of the Academic Senate of the University of Dayton.

Leader Perspectives From Policy To Practice: An Exploration Of Deiajb Accreditation Expectations In K-12 International Schools, Jennifer Lea Garzia

LMU Theses and Dissertations

In recent years, various school accreditation bodies have incorporated new standards and processes that focus on diversity, equity, inclusion, access, justice, and belonging (DEIAJB). Yet, how DEIAJB expectations are perceived and implemented remains underexplored. This study examines the perceptions of international school leaders in Brazil and Italy, and how they interpret and enact DEIAJB school accreditation expectations. In this qualitative exploratory study, ten international school leaders were interviewed. Guided by Shields’ Transformative Leadership Theory (2009), data were collected through semi-structured interviews and were analyzed using thematic coding. Findings revealed that leaders viewed DEIAJB accreditation expectations as a legitimizing framework that …

Transforming Dental Education Through Lived Experiences, Casper Jonker, Alex Cresswell-Boyes, Wendy Smith

Peninsula Dental School

No abstract provided.

Women With Moderate Anaemia Prior To Conception Benefited Most From Nutrition Interventions: A Secondary Analysis Of The Women First Preconception Maternal Nutrition Trial, Sumera Aziz Ali, Ka Kahe, Jeanine Genkinger, Linda Valeri, Sarah Saleem, Saleem Jessani, Robert Goldenberg, Jamie Westcott, Jennifer Kemp, Ana Garces, Lester Figueroa, Shivaprasad Goudar, Sangappa Dhaded, Richard Derman, Antoinette Tshefu Kitoto, Adrien Lokangaka, Melissa Bauserman, Elizabeth Mcclure, Marion Koso-Thomas, Louise Kuhn, Nancy Krebs

Global Health Articles

INTRODUCTION: The Women First (WF) Preconception Maternal Nutrition trial found greater benefits of small-quantity lipid-based nutrient supplements (SQ-LNS) for intrauterine growth among anaemic versus non-anaemic women at preconception. We investigated whether the benefits of SQ-LNS in improving markers of intrauterine growth occurred evenly across the mild to moderate spectrum of pre-pregnancy anaemia.

METHODS: We analysed WF data (n=2443 maternal-newborn dyads) from Pakistan, India, Guatemala and the Democratic Republic of Congo. Women received SQ-LNS either ≥3 months preconception through pregnancy (Arm 1); starting in the late first trimester (Arm 2); or not at all (Arm 3: control), with all supplementations discontinued …

Clinical Workflow Of Spine Stereotactic Radiotherapy And Radiosurgery: Insights From A Single-Institution Physics Perspective, Dennis Mackin, Gizem Cifter, Yana Zlateva, Jihong Wang, Yao Ding, Muhammad Shafiq Ul Hassan, Zhiheng Wang, Parmeswaran Diagaradjane, Fada Guan, Travis C Salzillo, Shane Krafft, Jing Li, Martin C Tom, Amol J Ghia, Tina Marie Briere

Faculty, Staff and Student Publications

Spine stereotactic radiotherapy and radiosurgery (SSRS) techniques, encompassing both fractionated stereotactic treatments and single-fraction radiosurgery, are widely used for the management of spinal metastases due to their ability to deliver highly conformal radiation while limiting dose to adjacent critical structures. Clinical outcomes following SSRS, including durable local control and acceptable toxicity, have been reported previously in multiple institutional series. In this manuscript, we describe the clinical workflow used to deliver SSRS at a high-volume academic center, with emphasis on the medical physics processes that support routine clinical practice. Key elements of the workflow include patient selection, treatment region-specific immobilization, CT …

Evaluation Of Vaping Cessation Infographics Among E-Cigarette Users: A Cross-Sectional, Mixed-Methods Study, Hongying Daisy Dai, Chenxi Shi, Sara Reyes, Summer Woolsey

Student Publications

Introduction: This rise in vaping has become a significant public health concern. This mixed-methods study aims to assess the impact of vaping cessation infographics on different cessation motivation and gather feedback regarding how the infographic could be further improved.

Methods: Current e-cigarette users completed an online cross-sectional survey in January 2022 through Prolific®. Participants evaluated a vaping cessation infographic. Eligible participants were adults aged 19-64 years, US residents, fluent in English, and current e-cigarette users. Participants completed a questionnaire with questions regarding demographics, e-cigarette use, and assessment of the liking of infographics. Poisson regressions were conducted to assess the associations …

Women In Law And The Draft, Thomas Helgerman, Benjamin David Pyle

Faculty Scholarship

Between 1964 and 1973, women’s representation in full-time law school programs rose fivefold, from 3.7% to 20.1%. This paper examines whether Vietnam War draft policy contributed to this increase. In 1968, men enrolled in law school lost eligibility for 2-S student deferments, threatening law schools’ tuition revenues and incentivizing schools to admit more women to stabilize enrollment. To test this mechanism, we construct a school-by-year dataset of enrollment counts split by women/men and full-time/part-time status. Using a uniform adoption difference-in-differences design, we find that women’s representation rises by 2 percentage points in full-time programs relative to part-time programs (which were …

Using The Linear References From The Pangenome To Discover Missing Autism Variants, Yang Sui, Jiadong Lin, Michelle D Noyes, Youngjun Kwon, Isaac Wong, Nidhi Koundinya, William T Harvey, Mei Wu, Kendra Hoekzema, Katherine M Munson, Gage H Garcia, Jordan Knuth, Julie Wertz, Tianyun Wang, Kelsey Hennick, Druha Karunakaran, Rafael A Polo Prieto, Rebecca Meyer-Schuman, Fisher Cherry, Davut Pehlivan, Bernhard Suter, Jonas A Gustafson, Danny E Miller, Human Pangenome Reference Consortium (Hprc), Hanna Berk-Rauch, Tomasz J Nowakowski, Aravinda Chakravarti, Huda Y Zoghbi, Evan E Eichler

Duncan NRI Faculty and Staff Publications

To better understand large-effect pathogenic variation associated with autism, we generated long-read sequencing (LRS) data to construct phased and near-complete genome assemblies (average contig N50 = 43 Mbp, QV = 56) for 189 individuals from 51 families with unsolved cases. We applied read- and assembly-based strategies to facilitate comprehensive characterization of de novo mutations, structural variants (SVs), and DNA methylation. Using LRS pangenome controls, we efficiently filtered >97% of common SVs exclusive to 87 offspring. We find no evidence of increased autosomal SV burden for probands when compared to unaffected siblings yet observe a suggestive trend toward an increased SV …

Tead-Independent Mechanisms Of Yap Function In Cardiomyocyte Cell Cycle Reentry, Bing Xie, Jeffrey Steimle, Vaibhav Deshmukh, Lin Liu, Chang-Ru Tsai, Todd R Heallen, Wyatt Paltzer, Yuka Morikawa, Fansen Meng, Jun Wang, James F Martin

Faculty, Staff and Students Publications

Adult mammalian hearts exhibit limited regenerative capacity because of the restricted renewal of cardiomyocytes. Recent studies reveal that mammalian hearts exhibit transient regenerative potential within a short time frame after birth, suggesting a regulatory mechanism that prevents adult hearts from initiating a regenerative response to cardiac injury. Here, we discovered that an active form of YAP, named YAP6SA, which is not inhibited by the Hippo signaling pathway and does not interact with TEADs, induces cardiomyocyte cell cycle reentry. In addition, YAP6SA interacts with scaffold protein MPDZ to regulate Rho GTPases and promote cell cycle progression in cardiomyocytes (CMs). Importantly, YAP6SA …

De Novo Variants In The Splicing Factor Gene Sf3b1 Are Associated With Neurodevelopmental Disorders, Kevin Uguen, Tiffany Bergot, Marie-Pier Scott-Boyer, Solène Chapalain, Camille Desdouets, Séverine Commet, Changlian Zhu, Yiran Xu, Yangong Wang, Tony Roscioli, Frederic Tran-Mau-Them, Laurence Faivre, Julien Maraval, Julian Delanne, Anne-Sophie Denommé-Pichon, Antonio Vitobello, Céline Jost, Marc Planes, Susan Hiatt, Patricia Wheeler, Claudia Gonzaga-Jauregui, Heng Wang, Baozhong Xin, Valerie Sency, Michael C Kruer, Somayeh Bakhtiari, Patrick Sulem, Cynthia Curry, Trine Prescott, Gertrud Strobl-Wildemann, Theresa Brunet, Martine Doco Fenzy, Thomas Courtin, Céline Poirsier, Trine Bjørg Hammer, Christina D Fenger, Melissa Macpherson, Kosuke Izumi, Jacqueline Leonard, Dong Li, Elaine H Zackai, Ian A Glass, Scott Ward, Philippe M Campeau, Maria Carla Hermida Borroto, Laurence Le Moigno, Hilde Van Esch, Liesbeth De Waele, Daniel G Calame, James R Lupski, Giulia Barcia, Cristina Peduto, Pauline Planté-Bordeneuve, Lucie Dupuis, Roberto Mendoza-Londono, Dimitri J Stavropoulos, Jennifer Gillibert-Duplantier, Thomas Besnard, Laura Do Souto Ferreira, Benjamin Cogné, Stéphane Bézieau, Arnaud Droit, Laurent Corcos, Eric Lippert, Claude Férec, Sebastien Küry, Delphine G Bernard

Faculty, Staff and Students Publications

SF3B1 is an essential and ubiquitous splicing factor that plays a pivotal role in the early steps of pre-mRNA splicing. Recurrent somatic missense mutations in SF3B1 are frequent in cancers, but no constitutional variant has been reported so far. We describe here a cohort of 26 individuals with neurodevelopmental disorders, harbouring SF3B1 constitutional heterozygous variants that appeared mostly de novo. Patients present with a global developmental delay, associated with variable neurological and facial dysmorphic traits. A dichotomy may emerge between patients harbouring predicted loss of function (n = 9) and missense variants (n = 17), the latter being associated with …

Hiv Vpr Induces Demethylation Of The Snca Antisense Promoter, Leading To Neurocognitive Impairment, Maryline Santerre, Ying Wang, Daniel Kalamarides, Jin Park, Lynn G Kirby, Jeannie Chin, Jaroslav Jelinek, Natalia Shcherbik, Bassel E Sawaya

Faculty, Staff and Students Publications

Human immunodeficiency virus type 1 (HIV-1) alpha-synuclein (α-Syn) aggregation is a hallmark of neurodegenerative diseases. Accumulation and aggregation of α-Syn are often observed in individuals with HIV-1 cognitive impairments. The direct mechanistic link between α-Syn dysregulation and HIV-associated neurocognitive disorders (HAND) remains unclear. Emerging evidence suggests that epigenetic changes, particularly deoxyribonucleic acid (DNA) demethylation, influence α-Syn regulation. We show that the HIV-1 protein viral protein R (Vpr) demethylates the antisense promoter within intron 1 of the alpha-synuclein gene (SNCA), potentially contributing to increased α-Syn expression. Elevated α-Syn promotes aggregation, causing synaptic dysfunction and impaired mitochondrial transport. These processes contribute to …

Saga/Atac Complexes Sustain Aberrant Chromatin Regulation And Promote Tumorigenesis In Diffuse Midline Glioma, Rosemary U Richard, Caitlin Bagnetto, Rebecca L Murdaugh, Brittany R Eberl, Alan L Jiao, Adam F Kebede, Barry M Zee, Margaret M Harrington, Mariella G Filbin, Akdes Serin-Harmanci, Yang Shi, Jamie N Anastas

Faculty, Staff and Students Publications

Diffuse midline gliomas (DMG) are aggressive pediatric brain tumors characterized by chromatin and transcriptional dysregulation induced by H3K27M mutations. Strategies for overcoming epigenetic dysfunction to reduce DMG tumorigenesis remain limited. We identified multiple components of the SAGA and ATAC chromatin regulatory complexes as DMG genetic dependencies and found that genetic or pharmacological inhibition of the SAGA/ATAC-associated chromatin reader SGF29 reduces DMG proliferation. Small molecules targeting SAGA/ATAC-associated histone acetylation, ubiquitination, and methylation similarly suppressed DMG growth. Further chromatin profiling and RNAseq analyses reveal that SGF29 controls H3K9ac and H3K4me3 dynamics at both H3K27M-bound and H3K27M-independent target genes linked to proliferation, differentiation, …