Digital Commons Network^™

Prompting For Multimodal Hateful Meme Classification, Rui Cao, Roy Ka-Wei Lee, Wen-Haw Chong, Jing Jiang

Research Collection School Of Computing and Information Systems

Hateful meme classification is a challenging multimodal task that requires complex reasoning and contextual background knowledge. Ideally, we could leverage an explicit external knowledge base to supplement contextual and cultural information in hateful memes. However, there is no known explicit external knowledge base that could provide such hate speech contextual information. To address this gap, we propose PromptHate, a simple yet effective prompt-based model that prompts pre-trained language models (PLMs) for hateful meme classification. Specifically, we construct simple prompts and provide a few in-context examples to exploit the implicit knowledge in the pretrained RoBERTa language model for hateful meme classification. …

Bank Error In Whose Favor? A Case Study Of Decentralized Finance Misgovernance, Ping Fan Ke, Ka Chung Boris Ng

Research Collection School Of Computing and Information Systems

Decentralized Finance (DeFi) emerged rapidly in recent years and provided open and transparent financial services to the public. Due to its popularity, it is not uncommon to see cybersecurity incidents in the DeFi landscape, yet the impact of such incidents is under-studied. In this paper, we examine two incidents in DeFi protocol that are mainly caused by misgovernance and mistake in the smart contract. By using the synthetic control method, we found that the incident in Alchemix did not have a significant effect on the total value locked (TVL) in the protocol, whereas the incident in Compound caused a 6.13% …

The Employment Situation Of Veterans: November 2022, Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

Veteran employment trends and statistics among various demographics during November 2022

Choosing Penumbra, Christina Melchiorre

Graduate Theses

Amaranthine | adjective

am·a·ran·thine | \ ˌa-mə-ˈran(t)-thən , -ˈran-ˌthīn \

1a : of or relating to an amaranth

b : Eternally beautiful and unfading; everlasting, undying

2 : of the color amaranth; a shade of reddish-rose

My work explores the narrative I have with family in relation to who I am and how I have developed as a result of both positive and negative influences. Despite the dysfunctional dynamics that I experience with my family, I choose to remain connected to them and continue to endure and persevere through the obstacles that they create. I particularly experience these moments through …

Rite Of Identity, Youmee Lee

Theses

Rite of Identity, a graduate thesis film, is a 2D animated visual poem of deaf children’s experiences. The film follows the protagonist’s journey in navigating a visual realm and a black-and-white realm, which represent the deaf world and the hearing world. Childhood experiences of struggling to assimilate into mainstream society are conveyed through the protagonist in the black-and-white realm. The purpose of the film is to encourage the viewers to think about what it is like for a child to be underestimated and to struggle with a soundscape that is not perceived naturally in the realm. Deaf children have a …

A Preliminary Exploration On The Views Of Terrorism Among Indian And U.S. College Students, Eric G. Lambert, Shanhe Jiang, N. Prabha Unnithan, Sudershan Pasupuleti

School of Social Work Faculty Publications

No corner of the world is completely safe from terrorist attacks. Both India and the United States have suffered horrific acts of terrorist-inspired violence. While views of terrorism vary for different reasons, culture certainly plays a role. A total of 918 undergraduate college students, composed of 434 Indian students and 484 U.S. students, were surveyed on their views of terrorism, responses to terrorism, and appropriate punishment of terrorists. Ordered ordinal regression results indicated a significant difference on 20 of the 26 items by nationality. Indian participants were more likely to express strong views on the problem of terrorism for society …

Identity Term Sampling For Measuring Gender Bias In Training Data, Nasim Sobhani, Sarah Jane Delany

Conference Papers

Predictions from machine learning models can reflect biases in the data on which they are trained. Gender bias has been identified in natural language processing systems such as those used for recruitment. The development of approaches to mitigate gender bias in training data typically need to be able to isolate the effect of gender on the output to see the impact of gender. While it is possible to isolate and identify gender for some types of training data, e.g. CVs in recruitment, for most textual corpora there is no obvious gender label. This paper proposes a general approach to measure …

Dendrimer-Based Drug Delivery Systems: History, Challenges, And Latest Developments, Juan Wang, Boxuan Li, Li Qiu, Xin Qiao, Hu Yang

Chemical and Biochemical Engineering Faculty Research & Creative Works

Since the first dendrimer was reported in 1978 by Fritz Vögtle, dendrimer research has grown exponentially, from synthesis to application in the past four decades. The distinct structure characteristics of dendrimers include nanoscopic size, multi-functionalized surface, high branching, cavernous interior, and so on, making dendrimers themselves ideal drug delivery vehicles. This mini review article provides a brief overview of dendrimer's history and properties and the latest developments of dendrimers as drug delivery systems. This review focuses on the latest progress in the applications of dendrimers as drug and gene carriers, including 1) active drug release strategies to dissociate drug/gene from …

Should All Car-T Therapy For Acute Lymphoblastic Leukemia Be Consolidated With Allogeneic Stem Cell Transplant?, Alejandro Marinos, Helen E Heslop

Faculty, Staff and Students Publications

Autologous T cells genetically modified with a CD19 chimeric antigen receptor are an effective therapy for children and adults with relapsed or refractory acute lymphoblastic leukemia with initial response rates ranging from 70 to 85%. Unfortunately, about half of these responding patients will subsequently relapse raising the question of whether allogeneic hemopoietic stem cell transplant should be considered as a consolidative therapy. Currently efforts are focused on defining risk factors for relapse to try and develop algorithms predicting which patients may benefit from allogenic transplant.

Psychiatric Comorbidities And Their Treatment Predict Buprenorphine Continuation Among Postpartum People With Opioid Use Disorder, Hannah Shadowen, Stephanie Violante, Andrea Gataric, Alison N Goulding, Caitlin E Martin

Faculty, Staff and Students Publications

BACKGROUND: Opioid use disorder (OUD) is a growing crisis among pregnant and postpartum people. Psychiatric comorbidities are common, yet how they impact OUD treatment outcomes is not well characterized. The aim of this study was to assess the association of psychiatric comorbidities and receipt of psychiatric treatment with buprenorphine continuation through one year postpartum among a sample of people with OUD.

METHODS: A subsample was identified from a larger retrospective cohort of patients receiving buprenorphine for OUD at the time of delivery from an academic medical center between 2017 and 2020. Medical record abstractions were conducted during pregnancy through one …

Standards For Evaluating Neonatal Growth Outcomes Using Individualized Pathological Growth Potential Realization Indices, Russell L Deter, Wesley Lee, Roberto Romero

Faculty, Staff and Students Publications

OBJECTIVE: Provide standards for detecting neonatal growth abnormalities with the average pathological Growth Potential Realization Index (av. pGPRI).

METHODS: Individualized Growth Assessment (IGA) evaluations of 117 neonates with normal growth outcomes were carried out using measurements of WT, HC, AC, ThC and CHL. Growth Potential Realization Index (GPRI) values for each parameter were calculated from predicted and actual birth measurements, the former obtained using Rossavik size models derived from the second-trimester growth potential estimates. Subtraction of either the upper and lower boundaries of GPRI reference ranges from these GPRI measurements gave + pGPRI and - pGPRI measurements. GPRI's within their …

Association Between Cause Of Kidney Failure And Fracture Incidence In A National Us Dialysis Population Cohort Study, Susan Ziolkowski, Sai Liu, Maria E Montez-Rath, Michelle Denburg, Wolfgang C Winkelmayer, Glenn M Chertow, Michelle M O'Shaughnessy

Faculty, Staff and Students Publications

Background: Bradycardia and asystole events are common among patients treated with maintenance hemodialysis. However, triggers of these events in patients on maintenance hemodialysis (HD), particularly during the long interdialytic period when these events cluster, are uncertain.

Methods: The Monitoring in Dialysis Study (MiD) enrolled 66 patients on maintenance HD who were implanted with loop recorders and followed for 6 months. We analyzed associations of predialysis laboratory values with clinically significant bradyarrhythmia or asystole (CSBA) during the 12 hours before an HD session. Associations with CSBA were analyzed with mixed-effect models. Adjusted negative binomial mixed-effect regression was used to estimate incidence …

Dawn-To-Dusk Dry Fasting Induces Anti-Atherosclerotic, Anti-Inflammatory, And Anti-Tumorigenic Proteome In Peripheral Blood Mononuclear Cells In Subjects With Metabolic Syndrome, Ayse L Mindikoglu, Jihwan Park, Antone R Opekun, Mustafa M Abdulsada, Zoe R Wilhelm, Prasun K Jalal, Sridevi Devaraj, Sung Yun Jung

Faculty, Staff and Students Publications

BACKGROUND: Metabolic syndrome characterized by abdominal obesity, high blood pressure, elevated fasting glucose and triglyceride levels and low high-density lipoprotein cholesterol level is associated with pro-inflammatory state, increased risk for atherosclerosis, and multiple cancers. Our previous results on subjects with metabolic syndrome showed that 4-week dawn-to-dusk (sunset) dry fasting resulted in significant changes in the serum proteome and improvement in several metabolic risk factors. Peripheral blood mononuclear cells (PBMC) proteomics is a powerful tool that can provide mechanistic insights into how dawn-to-dusk dry fasting affects protein expression in metabolic pathways at cellular level. In this study, we determined whether dawn-to-dusk …

A Fiber-Optic Sensor-Embedded And Machine Learning Assisted Smart Helmet For Multi-Variable Blunt Force Impact Sensing In Real Time, Yiyang Zhuang, Taihao Han, Qingbo Yang, Ryan O'Malley, Aditya Kumar, Rex E. Gerald, Jie Huang

Materials Science and Engineering Faculty Research & Creative Works

Early on-site diagnosis of mild traumatic brain injury (mTBI) will provide the best guidance for clinical practice. However, existing methods and sensors cannot provide sufficiently detailed physical information related to the blunt force impact. In the present work, a smart helmet with a single embedded fiber Bragg grating (FBG) sensor is developed, which can monitor complex blunt force impact events in real time under both wired and wireless modes. The transient oscillatory signal "fingerprint" can specifically reflect the impact-caused physical deformation of the local helmet structure. By combination with machine learning algorithms, the unknown transient impact can be recognized quickly …

Proteasome Inhibitors Silence Oncogenes In Multiple Myeloma Through Localized Histone Deacetylase 3 (Hdac3) Stabilization And Chromatin Condensation, Laure Maneix, Polina Iakova, Shannon E Moree, Joanne I Hsu, Ragini M Mistry, Fabio Stossi, Premal Lulla, Zheng Sun, Ergun Sahin, Sarvari V Yellapragada, André Catic

Faculty, Staff and Students Publications

Proteasome inhibitors have become the standard of care for multiple myeloma (MM). Blocking protein degradation particularly perturbs the homeostasis of short-lived polypeptides such as transcription factors and epigenetic regulators. To determine how proteasome inhibitors directly impact gene regulation, we performed an integrative genomics study in MM cells. We discovered that proteasome inhibitors reduce the turnover of DNA-associated proteins and repress genes necessary for proliferation through epigenetic silencing. Specifically, proteasome inhibition results in the localized accumulation of histone deacetylase 3 (HDAC3) at defined genomic sites, which reduces H3K27 acetylation and increases chromatin condensation. The loss of active chromatin at super-enhancers critical …

Distinctive Kidney Function Trajectories Following Left Ventricular Assist Device Implantation, Carl P Walther, Julia S Benoit, Harveen K Lamba, Andrew B Civitello, Kevin F Erickson, Nandan K Mondal, Kenneth K Liao, Sankar D Navaneethan

Faculty, Staff and Students Publications

BACKGROUND: The aim of this study was to assess for distinct kidney function trajectories following left ventricular assist device (LVAD) placement. Cohort studies of LVAD recipients demonstrate that kidney function tends to increase early after LVAD placement, followed by decline and limited sustained improvement. Inter-individual differences in kidney function response may be obscured.

METHODS: We identified continuous flow LVAD implantations in US adults (2016-2017) from INTERMACS (Interagency Registry for Mechanically Assisted Circulatory Support). Primary outcomes were estimated glomerular filtration rate (eGFR) trajectories pre-implantation to ∼12 months. Latent class mixed models were applied to primary and validation samples. Clinical differences among …

Comparative Effectiveness Of Surveillance Colonoscopy Intervals On Colorectal Cancer Outcomes In A National Cohort Of Patients With Inflammatory Bowel Disease, Hyun-Seok Kim, Ruben Hernaez, Shubhada Sansgiry, Akbar K Waljee, Frank I Scott, James D Lewis, Hashem B El-Serag, Jason K Hou

Faculty, Staff and Students Publications

BACKGROUND & AIMS: Surveillance colonoscopy is recommended to reduce colorectal cancer (CRC)-related morbidity and mortality in patients with inflammatory bowel disease (IBD). The comparative effectiveness of varying colonoscopy intervals on CRC outcomes among patients with IBD is unknown.

METHODS: We performed a retrospective cohort study of patients with confirmed CRC within a cohort of 77,824 patients with IBD during 2000 to 2015 in the National Veterans Health Administration. We examined the association between colonoscopy surveillance intervals on CRC stage, treatment, or all-cause and cancer-specific mortality. The interval of colonoscopy prior to CRC diagnosis was categorized as those performed within <1 >year, …

Analysis Of Genome-Wide Knockout Mouse Database Identifies Candidate Ciliopathy Genes, Kendall Higgins, Bret A Moore, Zorana Berberovic, Hibret A Adissu, Mohammad Eskandarian, Ann M Flenniken, Andy Shao, Denise M Imai, Dave Clary, Louise Lanoue, Susan Newbigging, Lauryl M J Nutter, David J Adams, Fatima Bosch, Robert E Braun, Steve D M Brown, Mary E Dickinson, Michael Dobbie, Paul Flicek, Xiang Gao, Sanjeev Galande, Anne Grobler, Jason D Heaney, Yann Herault, Martin Hrabe De Angelis, Hsian-Jean Genie Chin, Fabio Mammano, Chuan Qin, Toshihiko Shiroishi, Radislav Sedlacek, J-K Seong, Ying Xu, Impc Consortium, K C Kent Lloyd, Colin Mckerlie, Ala Moshiri

Faculty, Staff and Students Publications

We searched a database of single-gene knockout (KO) mice produced by the International Mouse Phenotyping Consortium (IMPC) to identify candidate ciliopathy genes. We first screened for phenotypes in mouse lines with both ocular and renal or reproductive trait abnormalities. The STRING protein interaction tool was used to identify interactions between known cilia gene products and those encoded by the genes in individual knockout mouse strains in order to generate a list of "candidate ciliopathy genes." From this list, 32 genes encoded proteins predicted to interact with known ciliopathy proteins. Of these, 25 had no previously described roles in ciliary pathobiology. …

Rsif Senegal Country Report 2022 - English, Regional Scholarship And Innovation Fund (Rsif)

Rsif Country Progress Reports

Senegal is a founding member of PASET and contributed USD 2 million to Rsif in 2020. There are 15 competitively selected Senegalese active Rsif PhD students (53% women) in five thematic areas in five different African Host Universities. University of Gaston Berger was competitively selected as an Rsif African Host University in ICT, including artificial intelligence and data science in 2017. The PhD programme in Computer Science at the African Center of Excellence (MITIC) is hosting 17 Rsif PhD scholars (41% women) from eight African nationalities. There is one Rsif alumni who graduated from UGB and 14 journal publications by …

Rsif Rwanda Country Report 2022, Regional Scholarship And Innovation Fund (Rsif)

Rsif Country Progress Reports

. Rwanda is the current chair of PASET and the first country to make a second additional USD 2 million contribution to Rsif. There are 22 competitively selected Rwandan Rsif PhD students in five thematic areas in eight different African Host Universities across the continent. There are so far four Rwandan Rsif alumni and 39 publications by Rwandan Rsif students. University of Rwanda was competitively selected as an Rsif African host university in ICT, including artificial intelligence and data science in 2019. The ACE Internet of Things (IoT) is hosting 18 Rsif funded students (44% women) from eleven different nationalities. …

Rsif Korea Country Report 2022, Regional Scholarship And Innovation Fund (Rsif)

Rsif Country Progress Reports

Government of Korea contributed USD 9 million to Rsif in 2018. There are 72 competitively selected Korean funded Rsif PhD students (44% women) from twenty Sub-Saharan African nationalities. They study across all five thematic areas in thirteen different African Host Universities. Seven advanced Korean institutions have signed MOUs with PASET to host Rsif students for research placement in Korea. So far 35 PhD students have been matched. There are 4 Rsif graduates who completed their research placement in Korea. Korea also supports 21 Rsif research projects implemented by faculty in African universities and returning Rsif graduates.

Rsif Ghana Country Report 2022, Regional Scholarship And Innovation Fund (Rsif)

Rsif Country Progress Reports

Ghana contributed USD 2 million to Rsif in 2020. Ghana is the current vice-chair of PASET. There are 22 competitively selected Ghanaian Rsif doctoral scholars (23% women) in four thematic areas in seven different Rsif African Host Universities across the continent. There are so far 1 Ghanaian Rsif alumni and 12 publications by Ghanaian Rsif students. University of Ghana (UG) was competitively selected as an Rsif African Host University in food security and agribusiness in 2019 (PhD Program in Applied Agricultural and Policy/Agribusiness). UG is hosting 29 Rsif funded PhD students (38% women) from ten different nationalities. Seven Rsif funded …

Rsif Benin Country Report 2022 - English, Regional Scholarship And Innovation Fund (Rsif)

Rsif Country Progress Reports

Benin contributed USD 2 million to Rsif in 2021. There are 20 competitively selected Beninese Rsif doctoral scholars (40% women) in five thematic areas in nine different Rsif African host universities across the continent. There are so far 1 Beninese alumnus and 7 publications by Beninese scholars. University of Abomey-Calavi was competitively selected as an Rsif African host university in ICT, including artificial intelligence and data science. In 2022, the PhD programme in Information technologies and communication at Institute of Mathematics and Physical Sciences, admitted eight Rsif funded students from three countries. Three projects in agri-based digital innovation are under …

Rsif Burkina Faso Country Report 2022 – English, Regional Scholarship And Innovation Fund (Rsif)

Rsif Country Progress Reports

Burkina Faso contributed USD 2 million to Rsif in 2020. There are 16 competitively selected Burkinabè Rsif doctoral scholars (1 woman, 15 men) registered in four thematic areas in seven different Rsif African host universities across the continent. Twelve of these started their studies in 2022. There are so far 4 journal publications by Burkinabè Rsif students. Institut International d'Ingénierie de l'Eau et de l'Environnement (2iE) was competitively selected as an Rsif African host university in Energy including renewables and admitted its first cohort of Rsif funded students in 2022. 2iE is hosting 13 Rsif students from five different African …

Rsif Côte D’Ivoire Country Report 2022 - English, Regional Scholarship And Innovation Fund (Rsif)

Rsif Country Progress Reports

Côte d’Ivoire contributed USD 1 million to Rsif in 2019. There are 11 competitively selected Ivorian Rsif PhD students (27% women) in four thematic areas in four different African host universities. Université Félix Houphouët-Boigny (UFHB) was competitively selected as an Rsif African host university in climate change in 2017. The Africa Center of Excellence for Climate Change Biodiversity and Sustainable Agriculture (CCBAD) is hosting 22 Rsif PhD scholars including 16 international students (36% women, 10 nationalities). There are so 1 Rsif alumni who graduated from UFHB and 16 publications by Rsif students at UFHB. An Rsif project for sustainable and …

Exploring Immersive Learning Experiences: A Survey, Mohammad Amin Kuhail, Areej Elsayary, Shahbano Farooq, Ahlam Alghamdi

All Works

Immersive technologies have been shown to significantly improve learning as they can simplify and simulate complicated concepts in various fields. However, there is a lack of studies that analyze the recent evidence-based immersive learning experiences applied in a classroom setting or offered to the public. This study presents a systematic review of 42 papers to understand, compare, and reflect on recent attempts to integrate immersive technologies in education using seven dimensions: application field, the technology used, educational role, interaction techniques, evaluation methods, and challenges. The results show that most studies covered STEM (science, technology, engineering, math) topics and mostly used …

Use Of Fenoldopam In Children With Congenital Heart Disease To Decrease Fluid Balance: A Retrospective, Descriptive Study And Insights Into Predictors Of Decreased Fluid Balance, Jacqueline Rausa, Rohit S Loomba, Vincent Dorsey, Priya Chandra, Jamie S Penk, Saul Flores, Enrique G Villarreal, Stuart L Goldstein

Faculty, Staff and Students Publications

This retrospective study aimed to determine if fenoldopam is associated with a decrease in fluid balance and to define the factors that may promote this in children with a history of congenital heart disease at the cardiac intensive care unit (CICU). Patients cared from January 2014 to December 2018 in the CICU were reviewed, and those on fenoldopam infusion were identified. Patient cohort data included demographics, clinical information, laboratory results, hemodynamic and urine output measurements, and information regarding fenoldopam infusion were compared between those with and without decrease in fluid balance. Forty-six patients were identified. Patients received a starting dose …

A Toddler With New Seizures, Progressive White Matter Lesions, And Multifocal Microhemorrhages, Dana Tlais, Stephanie Fetzko, Nitya Gulati, Huy Brandon D Tran, Sarah Risen, Yi-Chen Lai

Faculty, Staff and Students Publications

A 16-month-old, previously healthy male is hospitalized for new onset seizures. Initial investigation is significant for enterovirus/rhinovirus respiratory infection, abnormal T2 signal predominantly in the white matter and scattered microhemorrhages on brain MRI, transaminitis, and thrombocytopenia. His symptoms initially improve on steroid therapy and he is discharged from the hospital. During the ensuing month with the tapering of the steroids, he develops new motor deficits for which he is rehospitalized. His laboratory investigation on readmission is unremarkable. However, there is significant progression of white matter lesions and microhemorrhages on repeat MRI. While in the hospital, he becomes febrile and has …

Long Read Sequencing And Expression Studies Of Ahdc1 Deletions In Xia-Gibbs Syndrome Reveal A Novel Genetic Regulatory Mechanism, Varuna Chander, Medhat Mahmoud, Jianhong Hu, Zain Dardas, Christopher M Grochowski, Moez Dawood, Michael M Khayat, He Li, Shoudong Li, Shalini Jhangiani, Viktoriya Korchina, Hua Shen, George Weissenberger, Qingchang Meng, Marie-Claude Gingras, Donna M Muzny, Harsha Doddapaneni, Jennifer E Posey, James R Lupski, Aniko Sabo, David R Murdock, Fritz J Sedlazeck, Richard A Gibbs

Faculty, Staff and Students Publications

Xia-Gibbs syndrome (XGS; MIM# 615829) is a rare mendelian disorder characterized by Development Delay (DD), intellectual disability (ID), and hypotonia. Individuals with XGS typically harbor de novo protein-truncating mutations in the AT-Hook DNA binding motif containing 1 (AHDC1) gene, although some missense mutations can also cause XGS. Large de novo heterozygous deletions that encompass the AHDC1 gene have also been ascribed as diagnostic for the disorder, without substantial evidence to support their pathogenicity. We analyzed 19 individuals with large contiguous deletions involving AHDC1, along with other genes. One individual bore the smallest known contiguous AHDC1 deletion (∼350 Kb), encompassing eight …

Natural 2d Layered Mineral Cannizzarite With Anisotropic Optical Responses, Arindam Dasgupta, Xiaodong Yang, Jie Gao

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Cannizzarite is a naturally occurring mineral formed by van der Waals (vdW) stacking of alternating layers of PbS-like and Bi2S3-like two-dimensional (2D) materials. Although the PbS-type and Bi2S3-type 2D material layers are structurally isotropic individually, the forced commensuration between these two types of layers while forming the heterostructure of cannizzarite induces strong structural anisotropy. Here we demonstrate the mechanical exfoliation of natural cannizzarite mineral to obtain thin vdW heterostructures of PbS-type and Bi2S3-type atomic layers. The structural anisotropy induced anisotropic optical properties of thin cannizzarite flakes are explored through angle-resolved polarized Raman scattering, linear dichroism, and polarization-dependent anisotropic third-harmonic generation. …