Digital Commons Network^™

Colorectal Cancer Screening In Saudi Arabia: Current Challenges And Future Directions, Abdulrahman A. Aljabri, Abdulrahman G. Alharbi

Saudi Medical Journal

Colorectal cancer has become a major public health concern in Saudi Arabia. It is the most prevalent cancer among men and the third most prevalent among women. Although screening for people aged 45-75 is recommended by national recommendations, screening uptake is still below 10%, and less than 1% of older persons have a colonoscopy. With regional differences that vary from age-standardized rates of 3.2 per 100,000 in Jouf to 21.8 per 100,000 in Riyadh among men, approximately 29% of cases are detected at late stages. Therefore, we assessed the epidemiological, social, and health-related systemic structures preventing effective colorectal cancer screening …

Prevalence Of Carbapenem-Resistant Enterobacteriaceae In Intensive Care Units In Saudi Arabia: A 10-Year Systematic Review, Shadi A. Zakai

Saudi Medical Journal

Objective: To synthesize research on the prevalence and distribution patterns of carbapenem-resistant Enterobacteriaceae (CRE) in Intensive Care Units (ICUs) across Saudi Arabia. It also seeks to evaluate molecular resistance profiles, identify associated risk factors, assess antimicrobial susceptibility, and examine infection control strategies within these critical care settings.

Methods: A systematic analysis was conducted, including cross-sectional, retrospective, and genomic studies from various tertiary hospitals in Saudi Arabia. The review focused on epidemiological trends, molecular characterization of CRE strains, clinical correlates, and the outcomes of implemented intervention strategies.

Results: The findings indicate a high and steadily increasing prevalence of CRE, often exceeding …

The Student Movement Volume 110 Issue 12: Bundled Up And Unburdened, Corinna Bevier, Audrey Lim, Addison Randall, Megan Constantine, Alyssa Caruthers, Kyle Simpson, Ysabella Neves, Isa Demoraes, Trevor O'Reggio, Madison Vath, Nathaniel Reid, Andrew Francis

The Student Movement V. 110 (2025-2026)

ARTS & ENTERTAINMENT

Yet Another Cinderella Story: 'Bridgerton' Season 4 Review, Corinna Bevier

The Honors Department Goes to The Phantom of the Opera, Audrey Lim

Young Artists Prepare to Showcase Their Talents at the Upcoming Orchestra Concert, Addison Randall

HUMANS

"The Father's Love": AUSA Sabbath Recap, Megan Constantine

Student Perspectives on Black History Month, Alyssa Caruthers

NEWS

No Cold Feet at SILA's Annual AU's Got Talent Event, Kyle Simpson

Stuck Abroad: International Students Face Visa Barriers After Break, Ysabella Neves

Speaker Emphasizes Forgiveness During AU Spring Week of Prayer, Isa DeMoraes

IDEAS

Resurgence of Racism, Dr. Trevor O'Reggio

PULSE

Thoughts …

Mutations Altering The Dna Binding Domains Of The Human Rad52 Protein Exert Distinct Effects On Homologous Recombination Repair In Saccharomyces Cerevisiae, Glenn M. Manthey, Elise W. Wolf, Jason Xu, M. Cristina Negritto, Renee A. Bouley, Ruben C. Petreaca, Adam M. Bailis

College of Health Professions Faculty Papers

RAD52 is a conserved member of the homologous recombination repair (HRR) apparatus from yeast to humans. Mutating conserved amino acids in the internal and external DNA binding domains of the human RAD52 protein (HsRAD52) has discrete effects in vitro. Previous studies have shown that HsRAD52 supports multiple mechanisms of HRR in budding yeast, suggesting the utility of this model system for exploring the correspondence between losses of HsRAD52 function in vitro and their impact in vivo. We report that disrupting the internal and external DNA binding domains of HsRAD52 produced distinct effects on the repair of genomic DNA double-strand breaks …

Daily Eastern News: February 04, 2026, Eastern Illinois University

Daily Eastern News: 2025-2026

No abstract provided.

February 4, 2026 Faculty Senate Minutes, University Of South Carolina

Faculty Senate

No abstract provided.

Seeing Beyond The Words: What Interdisciplinary Methodologies Reveal About International Law, Matthew S. Erie, Mark Pollack, Wolfgang Alschner, Beth Simmons, Katerina Linos

Scholarly Articles in Law Reviews & Journals

INTRODUCTION: On April 24, 2025, the International Law and Social Science Interest Group debuted at the ASIL Annual Meeting with a panel that posed a deceptively simple question: how can social science tools advance the work of international lawyers? Chaired by Chantal Thomas, the session brought together Matthew Erie, Wolfgang Alschner, Beth Simmons, and Katerina Linos— scholars who bridge doctrinal and empirical inquiry—to show how ethnography, computational text analysis, counterfactual inference, and mixed-method design can illuminate legal puzzles that doctrine alone cannot solve. The four short essays in this symposium provide parallel illustrations of this core theme: Erie’s ethnographic approach …

A Case Of Dislocation And Successful Reduction Of A Right Anterior Shoulder Inside A Space Suit: Considerations For Future Protocols, Samuel Beger, Curtis Lowery, Nicolas Heft, Amran Asadi, Brandon Trapp, Jaime Mateus, Alejandro Garbino

Faculty, Staff and Student Publications

Shoulder dislocations are prevalent on Earth and pose unique challenges in spaceflight and spaceflight training, particularly during extravehicular activities (EVAs). This case report describes a 50-year-old male who experienced an anterior shoulder dislocation while performing an emergency egress exercise in a SpaceX EVA suit. The report describes the medical thought process, the operational constraints, and the reduction techniques employed to achieve a successful shoulder reduction without fully removing or damaging the suit. NASA estimates a high likelihood of shoulder injuries during long-duration lunar missions, emphasizing the importance of suit designs and rescue protocols. Quick and effective medical intervention is crucial, …

On The Need Of Pluralism And Common Ground In Sla, Simona Pekarek Doehler, Steven L. Thorne, Soren W. Eskildsen, Marije C. Michel

World Languages and Literatures Faculty Publications and Presentations

Hyperbolic claims that SLA is in crisis (!), that a unifying theory is overdue, or that research must be oriented toward pedagogy have resurfaced once again—most recently in the response by Lantolf et al. (2025) to the Special Issue on Synergies in Second Language Acquisition and Teaching (SLA/T) (Atkinson et al., 2025). Our own position is diametrically opposed to such claims.

Theoretical And Conceptual Approaches To Journalism Education, August E. Grant, Jeffrey S. Wilkinson, G. Nathan Carnes

Faculty Publications

Many journalism programs embrace the teaching hospital model because of its practical approach, employing working journalists as journalism educators. However, critics contend a more conceptual model of journalism education is needed. This essay explores the literature on journalism education models and seeks to integrate the teaching hospital and entrepreneurial journalism approaches with the revised Bloom's Taxonomy and Fink's Taxonomy of Significant Learning. Combined, these models provide a solid theoretical foundation for practical, applied journalism education. This essay applies these four models to journalism education, yielding a matrix of dimensions that can guide the creation or modification of curricula as well …

Comparison Of Surgical Treatment Patterns And Temporal Trends For Stage I-Iii Invasive Rectal Adenocarcinoma Among Regions In The United States, Whitney Elks, Declan Feery, Celina Cosme, Kavita Batra, Lance Horner, Charles St Hill, Ovunc Bardakcioglu

School of Medicine Faculty Research

Background: Practice patterns of surgical management of rectal adenocarcinoma vary among US regions. Nationwide, there has been an overall trend toward the performance of anterior resection (AR) over abdominoperineal resection (APR) in the surgical management of invasive rectal adenocarcinoma when feasible. It is suspected that this trend is adopted at a slower rate in underserved regions of the United States. Methods: Data from the NCDB for 2004–2019 was queried for patients with stage I-III rectal adenocarcinoma who underwent anterior resection (AR) or abdominoperineal resection (APR). Comparisons of AR versus APR were made among year, region, approach, and stage. Results: Of …

Understanding The Epidemiology Of Malaria In Zanzibar Through Molecular And Serological Analysis Of Samples Collected During Reactive Case Detection, Vanrun Goel, Wahida Hassan, Caroline Murphy, Barbara B. Choloi, Mohamed Ali, Shija J. Shija, Jeffrey A. Bailey, Anders Björkman, Billey E. Ngasala, Eric Rogier, Jonathan J. Juliano, Jessica T. Lin

Faculty Publications

Background

The Zanzibar archipelago has been a pre-elimination region for malaria thanks to rigorous control interventions, but recent surges in malaria cases have been observed. The contribution of non-falciparum species to the current malaria situation is unknown.

Method

This study investigates the epidemiology of falciparum and non-falciparum malaria species in Zanzibar. Leveraging plasma extracted from dried blood spots (DBS) collected during reactive case detection (RCD) activities across Unguja island from May 2022 to January 2023, we measured immunoglobulin G (IgG) responses to Plasmodium MSP1-19kD antigens using a multiplex bead-based immunoassay. Additionally, active infections were detected using species-specific real-time PCR.

Results …

Efficiency, Concentration, And Diversification: Portfolio Lessons From Indian Technology Equities, Davinder K. Malhotra, Shaurya Batra, Rahul Singh

School of Business Faculty Papers

This study examines the extent to which Indian technology equities generate sufficient returns relative to their inherent volatility and assesses whether intra-sector diversification can improve outcomes in this dynamic, high-risk sector. Drawing on data from January 2020 to April 2025, ten leading firms are analyzed using an integrated approach that incorporates traditional risk-adjusted indicators, downside-sensitive metrics, and a six-factor model featuring momentum. The results show clear heterogeneity in performance. Mid-cap innovators such as Persistent Systems and Coforge deliver positive and, in some cases, statistically significant alphas, while large-cap stocks including Infosys, Tata Consultancy Services (TCS), and Wipro provide stability but …

On The Legal-Theoretical Foundations Of Property Taxation Under State Ownership Of Land, Tianke Ban, Yilin Hou, Ping Zhang

Center for Policy Research

The general public and even some scholars challenge the legitimacy of levying the property tax under conditions where land is state-owned and multi-year land-use fees have already been collected at the time of house sales. This challenge points to the legal- theoretical foundations of property taxation: the core issue is whether the rights and economic utility of China's construction land-use-rights (CLUR) are sufficient to be treated as the object of property tax levy. China's Civil Law stipulates that CLUR holders have the rights to possess, use, and profit from the land during their use period, as well as the right …

New Host And Distributional Records For Helminth Parasites (Monogenoidea, Trematoda, Cestoda, Nematoda) Of Arkansas Reptiles (Testudines, Ophidia), C. T. Mcallister, C. R. Bursey, T. J. Fayton, S. E. Trauth, H. W. Robison

Journal of the Arkansas Academy of Science

Over the last decade or more, our collaborative research has provided noteworthy information on the helminth parasites of reptiles of Arkansas. Because several species still need to be surveyed from the state, some for the first time, there has been a general void of information on their parasites. We therefore examined 10 reptiles, including seven species/subspecies of turtles, as well as three species/subspecies of snakes for helminth parasites. Found were 24 taxa of parasites, including two monogeneans, 14 digeneans, one tapeworm, and seven nematodes. We document several new host and distributional records for these parasites from some reptiles of the …

White Undergraduate Students’ Perceptions Of Faculty Of Color, Jeffrey Cross

Graduate Theses, Dissertations, and Capstones

Despite decades of initiatives that promote the values of diversity, equity, and inclusion in higher education, the percentage of faculty who identify as people of Color still remains low. Experiences of discrimination and marginalization from White faculty colleagues and White students has been commonly reported by faculty of Color. While studies have examined these experiences from the faculty perspective, research addressing White students’ experiences with faculty of Color has been sparse. The purpose of this study was to examine White undergraduate students’ perceptions of faculty of Color at predominately White institutions and how these students understand the influence of racial …

Cmsi Note 19: China’S Blue-Water Research Fleet: Science In Service Of Strategy, Ryan D. Martinson

CMSI Notes

Introduction:
Today, the People’s Republic of China (PRC) owns the world’s largest fleet of blue-water marine scientific research vessels. While their operations are largely concentrated in the Western Pacific, an increasing number are reaching across the globe—from the Indian Ocean to the Arctic, and even the Western Hemisphere. In fact, as of this writing the Chinese research ship Tansuo 1, with its deep-sea manned submersible aboard, is operating in the Atacama Trench off the coast of northern Chile.

Key Takeaways:

• China’s marine scientific research fleet is expanding its operations around the world, including the Western hemisphere. Presently, a Chinese …

Gene Regulatory Programs Of Nk Cells Show That Ncam1 (Cd56) And Kirs Are Controlled By Genetically Polymorphic Distal Regulatory Elements, Mariam A. Salem, Aditi Varkey, Matthew D. Estrada, Kruthika Sharma, Caprice D. Eisele, Nitin Chakravarti, Dean A. Lee, Aharon G. Freud, Bethany L. Mundy-Bosse, Patrick L. Collins

Kimmel Cancer Center Faculty Papers

Owing to their immunoprotective properties, natural killer (NK) cells are critical for the innate immune response to pathogens, as well as a new wave of cancer immunotherapy that harnesses natural cytotoxicity. We sought to study the genetic and epigenetic drivers behind human-specific NK cell receptors, so that we can better understand the underlying cellular function. Here, we present a transcriptomic, proteomic (CITE-seq), and chromatin (single nuclei ATAC-seq) profiling of human peripheral NK cell subsets, which was then compared with genomic databases. Through integrative multi-omics, we demonstrate that CD56^bright versus CD56^dim NK cell subsets have differential distal regulatory element …

Relationship Between Perceived Leadership Styles And Millennial Membership Growth In Nonprofit Churches, Larry Latham

Walden Dissertations and Doctoral Studies

Despite the widespread decline in church membership and attendance among all mainline denominations, there was a particular concern about retaining the millennial generation. Church leaders need to understand this concern as a key indicator of millennial retention in nonprofit churches. The purpose of this quantitative study was to examine the relationship between millennial membership growth and perceived leadership styles, including authoritative, partnership, democratic, team oriented, relationship oriented, serving, people oriented, task oriented, and goal oriented leadership. The social exchange theory and resource-based view theory grounded this study. The archival data from 2011 to 2022 comprised 17,012 Millennial participants from 665 …

Doctrinal Intent Versus Institutional Reality: The Gulf Countries' Antitrust Objectives, Nora Memeti

Yearbook of Antitrust and Regulatory Studies

This paper examines the intriguing contrast between the ambitious goals of antitrust laws in the Gulf countries and the reality of their enforcement. While this region seeks to protect competition and curb monopolistic practices, only Kuwait and the Kingdom of Saudi Arabia (KSA) have made significant strides in achieving these ideals.

Through a comparative legal analysis, this paper examines how the statutory objectives of competition law in Qatar, Bahrain, Oman, and the UAE often remain more rhetorical than substantive, with enforcement primarily symbolic. In contrast, Saudi Arabia demonstrates some enforcement activity, although its alignment with legislative objectives remains uncertain. Kuwait's …

Multiparent Recombinant Inbred Lines Crossed To A Tester Provide Novel Insights Into Sources Of Cis And Trans Regulation Of Gene Expression, Fabio Marroni, Alison M Morse, Adalena V Nanni, Nadja Nolte, Patricka Williams-Simon, Luis G León-Novelo, Rita M Graze, Paul Schmidt, Elizabeth King, Lauren M Mcintyre

Faculty, Staff and Student Publications

To understand the relative importance of cis and trans effects on regulation, we crossed multi-parent recombinant-inbred lines (RILs) to a common tester and measured allele-specific gene expression in the offspring. Testing the difference of allelic imbalance between two RIL × Tester crosses is a test of cis or trans, depending on the RIL alleles compared. The study design also enables to separation of two sources of trans variation, genetic and environmental, detected via interactions with cis effects. We demonstrate the effectiveness of this approach in a long-read RNA-seq experiment in female abdominal tissue at two time points in Drosophila melanogaster. …

Spectrum, Volume 56, Issue 1, Sacred Heart University

Newspapers (Obelisk & Spectrum)

Highlights include: Debate Grows Over Trump’s Interest in Greenland -- Michael Larobina Named Interim Provost --  WCBT Dean Dr. David Taylor Resigning -- KD Brings Sisterhood and Service to Girl Scouts -- Mahoney Dives into Action

Ubiquitination Of Oncogenic Mutant P53 Via Attenuation Of Ribosome Biogenesis Machinery Effectively Inhibits Pancreatic Tumor Growth, Mudassier Ahmad, Sahir Sultan Alvi, Haider Ahsan, Carlos Perez, Andrew Massey, Vivek K Kashyap, Neeraj Chauhan, Emmanuel Anning, Manish K Tripathi, Dae J Kim, Nirakar Sahoo, Tamer Oraby, Murali M Yallapu, Mohammad Moshahid Khan, Manu M Sebastian, Subhash C Chauhan, Bilal B Hafeez

Faculty, Staff and Student Publications

Dysregulated ribosome biogenesis and p53 mutations are known to play oncogenic roles in various cancers, including pancreatic cancer. In this study, we demonstrated the therapeutic potential of BMH-21, a pharmacologic inhibitor of RNA polymerase I, against pancreatic cancer by uncovering a novel molecular mechanism involving RPA194-mediated ubiquitination of mutant p53 without affecting the ubiquitination of wild-type p53. Our key findings are that (i) BMH-21 selectively induces apoptosis and cell growth inhibition of pancreatic cancer cells with no effect on normal human pancreatic ductal epithelial cells; (ii) BMH-21 degrades RPA194; (iii) BMH-21 inhibits recruitment of both RPA194 and RPA135 on rDNA …

The Next Layer: Augmenting Foundation Models With Structure-Preserving And Attention-Guided Learning For Local Patches To Global Context Awareness In Computational Pathology, Muhammad Waqas, Rukhmini Bandyopadhyay, Eman Showkatian, Amgad Muneer, Anas Zafar, Frank R Alvarez, Maricel Corredor Marin, Wentao Li, David Jaffray, Cara Haymaker, John V Heymach, Natalie Vokes, Luisa M Solis Soto, Jianjun Zhang, Jia Wu

Faculty, Staff and Student Publications

Foundation models have emerged as powerful feature extractors in computational pathology. However, they typically omit mechanisms for leveraging the global spatial structure of tissues and the local contextual relationships among diagnostically relevant regions-key elements for understanding the tumor microenvironment. Multiple instance learning (MIL) remains an essential next step following the foundation model, designing a framework to aggregate patch-level features into slide-level predictions. We present EAGLE-Net, a structure-preserving, attention-guided MIL architecture designed to augment prediction and interpretability. EAGLE-Net integrates multi-scale absolute spatial encoding to capture global tissue architecture, a top-K neighborhood-aware loss to focus attention on local microenvironments, and background suppression …

New Englanders Oppose Iran Attack, Split On Assassination Of Khamenei 3/4/2026, Unh Survey Center

All UNH Survey Center Polls

Majorities in all six New England states oppose recent attacks on Iran by the United States and most believe President Trump should have asked for Congressional approval before conducting the strikes. However, many believe that the Iranian nuclear program represented a serious threat to the United States before the conflict began. New Englanders are divided on the decision to assassinate Ayatollah Ali Khamenei but generally oppose similar assassinations of political figures during armed conflicts.

Geochemical Fate Of Lead In Contaminated Residential Soils Following Application Of Amendments For Lead Immobilization, Hadeer Saleh, Washington Braida, Zhiming Zhang, Rupali Datta, Dibyendu Sarkar

Michigan Tech Publications

Background: Lead (Pb) persists in urban soils, where its partitioning among geochemical fractions governs mobility, bioavailability, and human health risk. These fractions are strongly controlled by soil physicochemical properties, necessitating site-specific remediation strategies. Methods: This study developed a site-specific Pb immobilization framework linking amendment selection to soil geochemistry and sustainability considerations. Pb-contaminated residential soils from three U.S. cities, San Antonio (alkaline), Baltimore (acidic), and Detroit (near-neutral), were treated with gypsum, biochar + lime, and alum, respectively. Changes in Pb speciation were tracked using sequential extraction over 7, 30, and 90 days. Results: All amendments significantly reduced exchangeable Pb (F1) and …

Early Postnatal Polymerase Chain Reaction Testing In The Identification Of Perinatal Transmission Of Hepatitis C Virus, Mona Prasad, Grecio J Sandoval, George R Saade, Brenna L Hughes, Rebecca G Clifton, Uma M Reddy, Anna Bartholomew, Ashley Salazar, Edward K Chien, Alan T N Tita, John M Thorp, Torri D Metz, Ronald J Wapner, Vishakha Sabharwal, Hyagriv N Simhan, Geeta K Swamy, Kent D Heyborne, Baha M Sibai, William A Grobman, Yasser Y El-Sayed, Brian M Casey, Samuel Parry, George A Macones

Faculty, Staff and Student Publications

In this study, a single hepatitis C virus (HCV) RNA at 2-6 months was sensitive and specific (86.7% and 95% confidence interval [CI], 62.1%-96.3% and 100% and 95% CI, 98.8%-100%, respectively) in identifying perinatal transmission of HCV. No cases of perinatal infection requiring treatment were missed.

Gain Of Function Notch4 Variants Disrupt Angiogenesis In Systemic Sclerosis, Urvashi Kaundal, Pei-Suen Tsou, Mousumi Sahu, Mengqi Huang, Steven E Boyden, Curtis M Woodford, Daniel Shriner, Emilee Stenson, Sarah Ayla Safran, Yuechen Zhou, Taylor A Talley, Kaavya Gudapati, Xuetao Zhang, Yosuke Kunishita, Janet Wang, Ami A Shah, Maureen D Mayes, Ayo P Doumatey, Amy R Bentley, Robyn Domsic, Thomas A Medsger, Paula S Ramos, Richard M Silver, Virginia Steen, John Varga, Vivien Hsu, Lesley Ann Saketkoo, Elena Schiopu, Jessica K Gordon, Lindsey A Criswell, Heather Gladue, Chris Derk, Elana J Bernstein, S Louis Bridges, Victoria Shanmugam, Lorinda Chung, Suzanne Kafaja, Reem Jan, Marcin Trojanowski, Avram Goldberg, Benjamin D Korman, James Mullikin, James W Thomas, Stefania Dell'orso, Davide Randazzo, Adebowale Adeyemo, Elaine F Remmers, Pamela L Schwartzberg, Ivona Aksentijevich, Charles Rotimi, Fredrick M Wigley, Rong A Wang, Francesco Boin, Dinesh Khanna, Robert Lafyatis, Daniel L Kastner, Pravitt Gourh

Faculty, Staff and Student Publications

Objectives: Vasculopathy and fibrosis are central to the pathogenesis of systemic sclerosis (SSc) and their genetic underpinnings are largely unknown. Here, we sought to examine the aetiology of severe vascular phenotypes and poorer outcomes in African American (AA) patients with SSc.

Methods: The study focuses on AA patients with SSc who have more severe vascular phenotypes and poorer outcomes and combines genetics, single-cell RNA sequencing, functional assays, and a mouse model to explore the role of NOTCH4 in SSc vasculopathy and the potential for NOTCH4-directed therapies.

Results: Gene-based testing identified NOTCH4 association at an exome-wide significance with SSc (P = …

2026-02-04 Border Protection Office Of Professional Responsibility Declines Career Fair Invitation, Kean Mathis

The Spectator Online

No abstract provided.

2026-02-04 Catholics Heads, Students Critique U.S. Foreign And Immigration Policy, Julia Pilch

The Spectator Online

No abstract provided.