Digital Commons Network^™

Crafting Power, Piety, And Memory: The Sabil-Maktab Of 'Abd Al-Rahman Katkhuda In Bayn Al-Qasrayn, Cairo (1157 Ah/ 1744 Ce), Nehal Hany Al-Shamy

Theses and Dissertations

Among hundreds of sabil-maktabs in Cairo, the one ʿAbd al-Rahman Katkhuda built in Bayn al-Qasrayn in 1157/1744 stands out as an iconic jewel, rising to be a symbol of the city itself. However, this sabil is more than just a beautiful building, for its beauty was only a means to channel political, commemorative, and spiritual connotations. This thesis is concerned with analyzing the raisons d’être of constructing the sabil through investigating the historical and political circumstances that influenced its patron at the time, and their reflections in the artistic choices he made. I argue that crafting the sabil as a …

Emergency-Use Vaccine Mandates And Bodily Integrity: Assessing The Validity Of Proportionality Test In Legal Frameworks, Eman Hussien Khalil

Theses and Dissertations

Courts confronting emergency-use vaccine mandates during pandemics have revealed that existing legal frameworks are not equipped to handle the emergency context, as seen in their inconsistent description of government measures and their limited capacity to integrate evolving scientific developments on EUA vaccines into proportionality analysis. This thesis argues that when mandates concern Emergency Use Authorized COVID-19 vaccines, courts must abandon the formalistic distinction between “mandatory” and “compulsory” measures and instead focus on whether the practical consequences of non-compliance remove an individual’s genuine choice; where they do, the measure is coercive in substance and triggers the examination of proportionality. Drawing on …

Journeys Of Emancipation, Struggle, Or Both? Accounts From Professional Egyptian Migrant Women In Germany, Adam Eddouss

Theses and Dissertations

This thesis explores the migration experiences of a group of professional Egyptian migrant women living in Germany. By employing a qualitative approach, primarily through semi-structured interviews, and guided by migration literature, this research attempts to move away from the oversimplistic approach that migration is an ‘either or’ reality. Mainstream migration scholarship, specifically that focusing on migrant women, tends to focus on depicting migration within an emancipation-struggle binary, presenting migrant women either as victims or as heroines. This work, antithetically, describes how migrant women experiences can be complex, highlighting, both instances of strength and struggle. Grounded in the words of the …

Gender, Integration, And Labor Market Access: The Case Of Syrian Refugees In Germany, Feras Al-Mekhlafy

Theses and Dissertations

Germany hosts one of the largest populations of Syrian refugees in Europe, making their successful labor market integration critical for social and economic stability. This study investigates the gender gap among Syrian refugees in Germany within the broader refugee–native labor market gap. Using cross-sectional data from the 2022 SOEP refugee survey, it applies a Heckman two-step selection model to jointly analyze employment and wage outcomes while correcting for selection bias. Results reveal that structural barriers (e.g.: legal and bureaucratic) and compositional factors (e.g.: human capital) rather than wage discrimination drive most observed disparities. Female refugees face significantly lower employment probabilities, …

Global Public Health Feasibility: Digital Dentistry In Geriatric Population, Merna Amr Saleh

Theses and Dissertations

Oral health is a critical yet often overlooked determinant of well-being among older adults in Egypt, where mobility limitations, geographic barriers, and low awareness of preventive practices exacerbate dental disparities. DentalPal, a teledentistry-based mobile application, was developed to provide older adults with remote dental consultations, oral hygiene advice, and triage guidance. The platform enables users to submit oral photographs or radiographs for assessment, seek second opinions, and initiate follow-up chats directly with the healthcare provider. This flexible design allows users to access dental consultations on demand while ensuring continuity of care The question that guided this study was how older …

Facebook Interaction As A Potential Marker Of Cognitive Decline: Pilot Study, Esraa M. Qansuwa

Theses and Dissertations

One of the critical challenges in brain disorder research is the early identification of individuals with mild cognitive impairment (MCI) who may later develop Alzheimer’s disease (AD) or other dementias. MCI in older adults is frequently associated with diminished social engagement and observable behavioral changes. With the rapid expansion of social media platforms and advances in Machine Learning (ML), digital traces from online activity present a novel and scalable avenue for mental health screening. In particular, predictive ML approaches have demonstrated strong potential in building reliable classifiers for early detection of neurocognitive decline. This study introduces an innovative framework that …

Artemisinin Partial Resistance Mutations In Zanzibar And Tanzania Suggest Regional Spread And African Origins, 2023, Sean V. Connelly, Julia G. Muller, Mohamed Ali, Billy E. Ngasala, Wahida Hassan, Bakari Mohamed, Kyaw L. Thwai, Jacob M. Sadler, Jacob Marglous, Abebe A. Fola, Abdallah Zacharia, Shija J. Shija, Safia Mohammed, Dominick C. Msolo, Hamza Said, Editruda E. Peter, Melic Odas, Isaack J. Rutha, Mwanaidi Nwange, Karamoko Naire, Shazia Ruybal-Pesántez, Robert Verity, Rebecca Crudale, Varun Goel, Barbara B. Choloi, Anders Björkman, Jeffrey A. Bailey, Jessica T. Lin, Jonathan J. Juliano

Faculty Publications

Artemisinin partial resistance, driven by Plasmodium falciparum K13 mutations, threatens malaria control. Zanzibar is vulnerable to artemisinin partial resistance spread but lacks recent molecular surveillance. We sequenced samples in Zanzibar and mainland Tanzania collected from 2022 to 2024. K13 mutations were found in 2 of 1440 participants (P441L, A675V) in Zanzibar and 6 of 3762 (R561H, P441L) in mainland Tanzania. Based on whole genome sequencing data, K13 mutations appear to be of African origin with regional spread. Frequent parasite importation appears to maintain partner drug mutation frequencies similar to the mainland, where artemether-lumefantrine selects for mutations favoring artesunate-amodiaquine sensitivity. Ongoing …

Reconfiguring The Category Of 'Sudan' Through The Literary Field: Representation, Disposability, Ambiguity And The 'Magical' In Four Post-Colonial Novels (2002-2022), Mourad Farahat

Theses and Dissertations

In this thesis I shall argue that contemporary African literature, with ‘’both its ethnographic imagination and anthropological complexity’’ (Orock, 2022, p.3), its use of ‘disruptive’ characters, and its focus on the embeddedness of the ‘collective’, the ‘common’ and the ‘vulgar’ in the personal (Mbembe, 2003), may help us mitigate some social scientific limitations on the study of Africa, and may aid us in understanding relations of power within the post-colony. I seek to show how contemporary Sudanese literature has already moved beyond the fixed social categories, lines, and limits which dominate some of the social scientific literature on Sudan. Literature …

Uncovering Potential Therapeutic Targets For Spinal Cord Injury; Insights From Single-Cell And Cross-Species Transcriptomics, Sara Samy Abouzekry

Theses and Dissertations

Central nervous system (CNS) injury remains a devastating healthcare problem. Despite years of research, it remains almost impossible to achieve meaningful functional repair following traumatic brain injury (TBI) and spinal cord injury (SCI). Spinal cord injury (SCI), a highly devastating subset of CNS trauma, is considered a challenge due to the extremely limited regenerative capacity of the nervous system in adult mammals. In contrast, certain species display remarkable repair abilities followed by moderate regenerative ability in neonatal mammals, indicating that regeneration is shaped by the evolutionary context as well as the developmental age.

To uncover the core molecular mediators of …

Research As A Reciprocal Act: How Rural Grade 5 And 6 Co-Researchers Transformed Their Adult Research Mentors, Bonnie Stelmach, Leah Peters, Rae Ann Van Beers

The Qualitative Report

Including children and youth in research contributes to their academic and life skills development, but how do co-researching experiences transform adult mentors?  Walkerdine (1997) stated that research “provides not only ways of seeing others, but ways of understanding ourselves” (p. 15). In this spirit, we report on our experiences to share how co-researching with eight Grade 5 and 6 students in a rural K-9 school in Alberta, Canada, which gave us insights into research and teaching assumptions and practices. Data were collected from observations of the students co-conducting interviews with K-6 research participants, students’ self-assessments of their co-researching experiences, transcripts …

Psycholinguistic Factors And Technology Appropriation In Efl Learning: An Instrumental Case Study, Marlon Vanegas Rojas, Claudia María Uribe Hoyos

The Qualitative Report

This instrumental case study described the psycholinguistic factors related to technology appropriation and language learning among English as a foreign language university students in Medellín, Colombia. Conducted at a private university’s language department, the 64-hour English course combined traditional and digital teaching methods with 22 participants from diverse undergraduate programs. Employing maximum variation sampling, the study captured perspectives across age, gender, technology appropriation, academic performance, and cultural background. Data collection included interviews, a technology appropriation self-perception survey, language proficiency tests, and classroom observations. Using the analytical framework of Miles et al. (2014) the analysis revealed that students relied on digital …

Clinical, Genetic, And Familial Features Of Pot1 Tumor Predisposition Syndrome, Courtney D Dinardo, Jennifer Croden, Hiam M Abdel-Salam, Tapan Kadia, Matteo Molica, Alexandre Bazinet, Prithviraj Bose, Abhishek Maiti, Fadi Haddad, Jan Burger, Hagop Kantarjian, William Wierda, Nitin Jain, Alessandra Ferrajoli

Faculty, Staff and Student Publications

Background: Protection of telomere 1 (POT1) tumor predisposition syndrome (POT1-TPD) is a hereditary leukemia syndrome that is identified in ∼5% of patients with chronic lymphocytic leukemia (CLL) and is characterized by a predisposition to other cancers, including gliomas, melanomas, and angiosarcomas. This study reports clinical and genetic characteristics of a large cohort of individuals with POT1-TPD.

Materials and methods: Individuals with pathogenic/likely pathogenic germline POT1 variants referred to the Hereditary Hematologic Malignancy Clinic at The University of Texas MD Anderson Cancer Center were included. Individuals with variants of uncertain significance were included if found to have telomeres >90th percentile of …

Control Arm Overperformance In Phase 3 Oncology Clinical Trials, Ansel P Nalin, Pavlos Msaouel, Adam J Grippin, Ramez Kouzy, Joseph Abi Jaoude, Timothy A Lin, Avital M Miller, Noah S Meimoun, Ethan B Ludmir, Alexander D Sherry

Faculty, Staff and Student Publications

Background: In randomized clinical trials (RCTs), anticipating control arm outcomes is important for power calculations and enrollment goals. Unexpected overperformance of the control arm can underpower RCTs. The objective of this study was to estimate the prevalence of control arm overperformance in phase 3 oncology RCTs.

Methods: The authors conducted a meta-epidemiological study of two-arm, superiority-design, phase 3 oncology RCTs. They reviewed articles/publications and protocols for power calculations, justification, and outcomes. Control arm performance was measured as the ratio of observed control arm outcomes relative to pretrial estimates, and overperformance was defined as a 10% improvement.

Results: In total, 385 …

Antidepressant Use In Older Age Bipolar Disorder (Oabd): Results From The Gage-Bd International Consortium, Christina Rigas, Paola Lavin, P J Chen, Susana G Torres-Platas, Chien-Lin Su, Lisa T Eyler, Andrew T Olagunju, Antonio L Teixeira, Annemieke Dols, Martin Alda, Osvaldo P Almeida, Kursat Altinbas, Vicent Balanzá-Martínez, Izabela G Barbosa, Hilary P Blumberg, Farren B S Briggs, Cynthia V Calkin, Brent P Forester, Orestes V Forlenza, Tomas Hajek, Barthomeus C M Haarman, Esther Jimenez, Beny Lafer, Benoit Mulsant, Stephen O Oluwaniyi, Regan Patrick, Joaquim Radua, Kaylee Sarna, Sigfried Schouws, Christian Simhandl, Jair C Soares, Ashley N Sutherland, Shang-Ying Tsai, Eduard Vieta, Luca M Villa, Nicole Fiorelli, Paula Villela Nunes, Joy M Yala, Martha Sajatovic, Soham Rej, All Gage-Bd Investigators

Faculty, Staff and Student Publications

Background: Antidepressants are still commonly prescribed in bipolar disorders, despite ongoing controversy of the potential risk of inducing hypomania/mania. There is limited knowledge about the characteristics of antidepressant use in older age bipolar disorder (OABD; age ≥50) in the current literature.

Aim: To describe antidepressant use, sociodemographic and clinical correlates of a global sample of OABD individuals.

Methods: The Global Aging and Geriatric Experiments in Bipolar Disorder (GAGE-BD) consortium provided cross-sectional international data on OABD individuals (n = 746) and younger-age bipolar disorder (YABD, age < 50 years; n = 692) regarding antidepressant use. Multivariate logistic regression was employed to assess the association between AD use with demographic and clinical variables.

Results: Of 1252 participants, 33.1 % of OABD individuals and 38.1 % of YABD individuals …

Beliefs Of Beginner Pedagogical Researchers About Computer-Assisted Qualitative Data Analysis, Kálmán Sántha

The Qualitative Report

This paper explores how computer-assisted qualitative data analysis appears in the beliefs and practical work of beginner researchers. The paper outlines the advantages of computer-assisted qualitative data analysis for beginner researchers, identifies the problems that may arise during this process, and discusses the topics where software capable of analysing multi-coded data can be utilised. The investigation was conducted through structured interviews. The text corpora were processed using a combined method that incorporated theory-driven deductive and data-driven inductive processes.  The following were discussed: advantages and problems with computer-assisted qualitative data analysis, and topics where software for analyzing qualitative data can be …

Neuproio: A Dual-Action Solid Drug Nanoparticle Topical Formulation For Simultaneous Intraocular Pressure Reduction And Neuroprotection For Glaucoma, Lei Xu, Mu Li, Lin Qi, Tzu Chen Wang, Dong Liu, Vimalin Jeyalatha Mani, Hsin Yin Chuang, Qingbo Yang, Ruipu Mu, Samira Mahdi, Da Huang, Honglan Shi, Yang Hu, Hu Yang

Chemical and Biochemical Engineering Faculty Research & Creative Works

Glaucoma is a leading cause of irreversible blindness, primarily due to elevated intraocular pressure (IOP) that damages the retina and optic nerve. Most topical glaucoma treatments focus solely on IOP-lowering without direct neuroprotection, as drug delivery to the posterior eye is challenging. Here, we developed NeuProIO, a dual-action solid drug nanoparticle (NP) eye drop for simultaneous IOP reduction and neuroprotection. Using flash nanoprecipitation in a multi-inlet vortex mixer, we fabricated the first NeuProIO solid drug NPs incorporating the repurposed neuroprotective agent maprotiline (MAP) and the IOP-lowering agent betaxolol (BX), forming MAP/BX NPs for synergistic glaucoma treatment. The NeuProIO improved stability …

Epigenetic Age Acceleration In Young Adults With Congenital Heart Disease, Parag N Jain, Beryl C Zhuang, Joanne Whitehead, Julia L Macisaac, Kristy Dever, Mallory Gahm, Peter Ermis, Thomas W Mcdade, Michael S Kobor, Paul A Checchia

Faculty, Staff and Students Publications

Background: Adults with congenital heart disease (ACHD) having undergone palliative surgery experience chronic stress due to altered physiology and repeated surgical interventions since infancy.

Objectives: To investigate whether ACHD, who had experienced chronic physiological stress from their underlying condition and early-life cardiac surgeries, was associated with epigenetic age acceleration (EAA) and other DNA methylation (DNAm)-based biomarkers, and to assess the potential contribution of derived inflammatory markers to EAA.

Methods: A case-control study comparing ACHD patients and healthy adults. Whole blood DNAm profile was used to estimate DNAm-based blood cell type proportions, multiple epigenetic age measures, and interleukin-6 (IL-6) and C-reactive …

Adolescent Math Anxiety: Teachers' Grouping Approach At The Intersection Of Multiple Student Identities, Dara Shifrer, Hannah Sean Ellefritz, David Hernandez-Saca, Allison Roda, Karla Santana Martinez

Sociology Faculty Publications and Presentations

Math anxiety represents a substantial barrier to many students’ math learning. In this paper, we apply interdisciplinary perspectives to data on over 13,200 ninth graders and their math teachers from the High School Longitudinal Study. Results suggest that being perceived as dis/abled relates to heightened math anxiety regardless of adolescents’ gender, or race and ethnicity. Our intersectional approach reveals that adolescents’ expressions of math anxiety do not always correspond with gender, racial, and ethnic stereotypes, with Black girls, Black boys, and Latine boys expressing relatively low levels of math anxiety. Finally, consistent with the principles of inclusion and universal design, …

Ichps Special Issue Introduction, Donna Coffman, Recai M. Yucel

Faculty Publications

No abstract provided.

On Cartan’S Examples Of Isoparametric Hypersurfaces And Their Focal Submanifolds, Thomas E. Cecil, Patrick J. Ryan

Mathematics and Computer Science Department Faculty Scholarship

This paper is a survey of Cartan’s examples of isoparametric hypersurfaces in spheres and their focal submanifolds that were described in his fundamental work on the subject, which appeared in four papers [2]–[5] published during the period 1938–1940.

Integrating Future Factory-To-Factory (F2f) Manufacturing Through System Of Systems Engineering (Sose): A Framework For Capability Beyond Constituent Systems, Polinpapilinho F. Katina, Hengtao Tang Ph.D., Anouar Hallioui

Faculty Publications

System of Systems Engineering (SoSE) is an emerging discipline focused on the design, integration, and evolution of metasystems—composed of multiple autonomous yet interdependent systems. These systems of systems (SoS) offer capabilities that exceed those of any individual constituent systems by enabling synergistic coordination, interoperability, and dynamic adaptation across diverse operational contexts. This study pursued three primary objectives: (i) to examine the role of integration in enabling emergent capabilities beyond those of individual systems, (ii) to explore SoSE as a framework for orchestrating Future Factory-to-Factory (F2F) Manufacturing, and (iii) to assess the implications of SoSE to address volatile, uncertain, complex, and …

Mobility, Migration, And Cultural Political Economy: Personal Narratives Of Immigration Policy, Max Crumley-Effinger

Journal of Comparative & International Higher Education

This study embraces the opportunity to explore students’ immigration experiences from a cultural political economy (CPE) perspective, beginning with a review of literature relevant to understanding students’ perspectives of host nation international student mobility and migration (ISM) policy, followed by an outline of the CPE theoretical framework. The study’s methodology is presented, outlining how findings were obtained through a qualitative content analysis of interviews with 40 international students studying in Australia, Canada, and the United States. Findings are then presented through the words of study participants, highlighting how international students connect their ISM policy experiences with the local CPE contexts …

Delivering Inclusive Cultural Offers For Social Prescribing: A Realist Evaluation Involving Older People From Global Majority Backgrounds And Cultural Sector Providers In The Uk, Debra Westlake, Kamal R. Mahtani, Geoffrey Wong, Jordan Gorenberg, Marta Santillo, Kerryn Husk, Sofia Vougioukalou, Ruthanne Baxter, Shoba Dawson, Caroline M. Potter, Harriet Warburton, Beth Mcdougall, Stephanie Tierney

Peninsula Medical School

Introduction: Research shows cultural activities benefit older people's wellbeing, but little is known about why individuals from global majority (minority ethnic) groups engage less with the mainstream cultural sector, or how it could adapt to meet their needs and encourage engagement. The TOUS study (Tailoring cultural Offers with and for diverse older Users of Social prescribing) investigated the question: What tailoring is needed, how, when and for whom, to optimise cultural offers as part of social prescribing for older people (aged 60+) from global majority groups?. Methods: The TOUS study involved focused ethnographies with six cultural-sector organisations throughout the United …

Navigating Care And Self-Care: Understanding Latina Caregivers’ Prioritization And Engagement In Self-Care Practices, Denise A. Longoria, John M. Gonzalez, Romeo Escobar, Nelda Rodriguez

School of Social Work Faculty Publications

Introduction: Latina caregivers face significant physical and mental health risks due to the demands of caregiving. The decision to become a caregiver is often influenced by various factors including cultural values such as familismo and marianismo. It is essential that caregivers recognize the importance of self-care to prevent burnout. Without self-care, caregivers face an increased risk of stress, which can negatively affect physical and emotional health.

Methods: A qualitative approach using focus groups to explore Latina caregivers’ understanding and engagement in self-care.

Results: Findings suggested that participants understand the need for self-care; however, family and cultural needs were prioritized. When …

Safety Of Carotid Endarterectomy In The Elderly And Octogenarian Population: A Nationwide Study Including 80,000 Patients, Victor Gabriel El-Hajj, Joanna Roy, Basel Musmar, Wi Jin Kim, Michael Rizzuto, Nathaniel Ellens, Rabab Alshahrani, Victor Staartjes, Adrian Elmi-Terander, Ramachandra Tummala, Stavropoula Tjoumakaris, Michael Gooch, Robert Rosenwasswer, Ziad Khabbaz, Pascal Jabbour

Department of Neurosurgery Faculty Papers

INTRODUCTION: Carotid endarterectomy (CEA) is an established procedure for stroke prevention in patients with carotid artery stenosis. While CEA is considered safe in younger patients, perioperative risks in octogenarians remain debated, with current guidelines classifying the procedure as "high-risk" in this patient population. This study aimed to evaluate short-term outcomes of CEA across age groups and to assess whether comorbidity burden better predicts outcomes than chronological age.

METHODS: The ACS-NSQIP database (2013-2020), was used to identify patients eligible for inclusion. The cohort was stratified based on age <  60, 60-80, and > 80 years. Propensity score matching and multivariable logistic regression were used to compare …

Charting A New Era To Modernize United States Infant Formula Regulation, Douglas G Burrin, Amy B Hair, Sharon M Donovan

Children’s Nutrition Research Center Staff Publications

No abstract provided.

Translator Professional Identity Under Market Demands: A Qualitative Analysis Of Job Advertisements In The Saudi Translation Market, Dr. Saad Salem Alshamrani

UB Journal for Humanities

This study examines how the professional translator identity develops in the Saudi translation market through recruitment discourse. It employs a qualitative analysis approach of Saudi job advertisements to address the research objectives. The researcher compiled a corpus of sixty Arabic and English translation related job advertisements publicly published on certain major platforms across Saudi Arabia. The analysis of these advertisements aims to explore how the employer expectations shape out the professional roles, skills, competencies and values. Equally important, the analysis probed on how the job advertisements meticulously detail the market demands and professional criteria through recurring requirements and evaluative descriptors. …

The Muslim Woman In Diaspora And The Reconstruction Of Identity In Leila Aboulela’S Minaret, Mashhoor Abdu Al-Moghales

UB Journal for Humanities

Identity reconstruction frequently represents a major challenge for immigrants who settle in a new land. Leila Aboulela (b. 1964) presents the complexities faced by the diaspora of Muslim women in constructing a new identity that aligns with their new reality, without forgetting or affecting their original roots. In Minaret (2005), Aboulela highlights the strength and independence of the Muslim woman through her female character, Najwa, presenting Muslim women as successful and resilient, in defiance of prevailing stereotypes. Drawing on Lila Abu-Lughod’s anthropological critique in Do Muslim Women Need Saving? alongside Homi Bhabha’s theories of hybridity and the Third Space, the …

The Language Matters In Restaurant Menus: The Saudi Arabian Marketing Perspective, Abdulaziz Khalid Alotaibi

UB Journal for Humanities

The study investigates the effect of variations of menu language on customer purchasing decisions in Saudi Arabian restaurants operating under fixed price systems. Furthermore, the study examines how different linguistic approaches used in menu descriptions impact customer ordering behaviors within the Saudi hospitality industry’s unique culture and multilingual setting. Thus, a cross-sectional quantitative survey employed experimental vignettes across four language conditions: basic descriptions, sensory-rich descriptions, culturally authentic words, and premium positioning phrases. Hence, through an application of stratified random sampling, data were collected from 447 restaurant customers living in Saudi Arabia’s five most significant metropolitan areas. The findings indicated that …

Afterwords: Make Mine A Double, Anthony Aycock

Creative Nonfiction Magazine

No abstract provided.